Detailed information for compound 1406890

Basic information

Technical information
  • TDR Targets ID: 1406890
  • Name: T0400-2025
  • MW: 430.451 | Formula: C22H26N2O7
  • H donors: 2 H acceptors: 2 LogP: 1.48 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Nc1ccc2c(c1)OCCOCCOc1c(OCCO2)ccc(c1)NC(=O)C
  • InChi: 1S/C22H26N2O7/c1-15(25)23-17-3-5-19-21(13-17)30-9-7-27-8-10-31-22-14-18(24-16(2)26)4-6-20(22)29-12-11-28-19/h3-6,13-14H,7-12H2,1-2H3,(H,23,25)(H,24,26)
  • InChiKey: NKJAIYNYGWCZQV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • MLS001005636
  • SMR000348945

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Giardia lamblia Fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Treponema pallidum fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.8 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Mycobacterium ulcerans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 26.9 %
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi RNA, U transporter 1 0.0256 0.0398 0.3282
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0027 0.0005 0.0015
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.2197 0.3733 1
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0112 0.015 0.1934
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0014 0.0014
Echinococcus granulosus cathepsin l1 0.0028 0.0007 0.0007
Entamoeba histolytica hypothetical protein 0.0223 0.0342 0.438
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0047 0.0047
Schistosoma mansoni retinoic acid receptor RXR 0.0062 0.0064 0.0064
Echinococcus multilocularis transcription factor btf3 0.0034 0.0017 0.0017
Echinococcus granulosus tubulin beta 1 chain 0.0476 0.0777 0.0777
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0017 0.0122
Leishmania major p-glycoprotein 0.0086 0.0106 0.1314
Trypanosoma brucei p-glycoprotein 0.0027 0.0005 0.0015
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0052 0.0048 0.0567
Mycobacterium tuberculosis Probable reductase 0.0233 0.036 0.095
Mycobacterium ulcerans cell division protein FtsZ 0.011 0.0148 0.0383
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0051 0.0655
Leishmania major importin beta-1 subunit, putative 0.0073 0.0084 0.1033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.035 0.035
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0066 0.0072 0.0883
Echinococcus granulosus survival motor neuron protein 1 0.0548 0.09 0.09
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0027 0.0005 0.0015
Entamoeba histolytica P-glyco protein 6, putative 0.0086 0.0106 0.1331
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0565 0.4774
Trichomonas vaginalis tubulin alpha chain, putative 0.0144 0.0206 0.1723
Schistosoma mansoni hypothetical protein 0.0961 0.161 0.161
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0066 0.0072 0.0578
Echinococcus multilocularis ATP binding cassette sub family B 0.0027 0.0005 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0318 0.0504 0.0504
Echinococcus multilocularis neuropeptide s receptor 0.1982 0.3363 0.3363
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0383
Toxoplasma gondii hypothetical protein 0.0112 0.015 0.1892
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0046 0.054
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0008 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0086 0.1065
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0078 0.0956
Plasmodium vivax thioredoxin reductase, putative 0.0102 0.0134 0.1728
Onchocerca volvulus Protein ultraspiracle homolog 0.0062 0.0064 0.0541
Loa Loa (eye worm) hypothetical protein 0.024 0.0372 0.2297
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.0051 0.0655
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0212 0.0323 0.0854
Schistosoma mansoni nuclear receptor 0.0029 0.0008 0.0008
Leishmania major cathepsin L-like protease 0.0028 0.0007 0.0033
Schistosoma mansoni tubulin subunit beta 0.0476 0.0777 0.0777
Entamoeba histolytica P-glycoprotein-2, putative 0.0086 0.0106 0.1331
Plasmodium falciparum glutathione reductase 0.0102 0.0134 0.1728
Plasmodium vivax multidrug resistance protein 1, putative 0.0086 0.0106 0.1359
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0076 0.0089 0.0225
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0248 0.0384 0.2376
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0038 0.0025 0.0025
Trypanosoma brucei beta tubulin 0.0476 0.0777 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0008 0.0068
Schistosoma mansoni tubulin subunit delta 0.011 0.0148 0.0148
Echinococcus granulosus beta tubulin 0.0476 0.0777 0.0777
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0027 0.0005 0.0015
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0078 0.0956
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0112 0.015 0.1424
Loa Loa (eye worm) DR-78 0.0029 0.0008 0.0036
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0062 0.0064 0.0064
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0014 0.0014
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0027 0.0005 0.0021
Schistosoma mansoni hypothetical protein 0.0223 0.0342 0.0342
Trichomonas vaginalis tubulin epsilon chain, putative 0.0351 0.0561 0.4743
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0035 0.0019 0.0198
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0046 0.0367
Loa Loa (eye worm) tubulin alpha chain 0.0351 0.0561 0.3476
Schistosoma mansoni protein phosphatase 2C 0.0052 0.0048 0.0048
Schistosoma mansoni hypothetical protein 0.0122 0.0167 0.0167
Entamoeba histolytica P-glycoprotein-5 0.0086 0.0106 0.1331
Loa Loa (eye worm) alpha-tubulin 0.0351 0.0561 0.3476
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.027 0.0422 0.3479
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.005 0.0045 0.0527
Trichomonas vaginalis tubulin beta chain, putative 0.0351 0.0561 0.4743
Trypanosoma brucei tubulin delta chain 0.011 0.0148 0.1863
Trypanosoma brucei protein kinase, putative 0.0051 0.0046 0.054
Echinococcus multilocularis neuropeptide receptor A26 0.1982 0.3363 0.3363
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0086 0.0107 0.0107
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0062 0.0064 0.0064
Leishmania major trypanothione reductase 0.0102 0.0134 0.1685
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0086 0.0106 0.0875
Entamoeba histolytica P-glycoprotein-1 0.0086 0.0106 0.1331
Echinococcus multilocularis dnaJ subfamily B 0.0833 0.139 0.139
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0041 0.0323
Loa Loa (eye worm) tubulin beta-1 chain 0.0476 0.0777 0.4818
Leishmania major zeta tubulin, putative 0.011 0.0148 0.1863
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0022 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0086 0.1065
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0036
Leishmania major beta tubulin 0.0476 0.0777 1
Leishmania major beta tubulin 0.0476 0.0777 1
Echinococcus multilocularis zinc finger protein 0.0063 0.0066 0.0066
Entamoeba histolytica hypothetical protein 0.0223 0.0342 0.438
Echinococcus granulosus lamin 0.0085 0.0104 0.0104
Entamoeba histolytica hypothetical protein 0.0027 0.0005 0.0033
Echinococcus granulosus tubulin beta 4A class IVa 0.0476 0.0777 0.0777
Loa Loa (eye worm) transcription factor SMAD2 0.0727 0.1208 0.7503
Giardia lamblia Epsilon tubulin 0.011 0.0148 0.1879
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0086 0.1065
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0422 0.3561
Brugia malayi AMP-binding enzyme family protein 0.007 0.0078 0.0625
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0086 0.1065
Leishmania major beta tubulin 0.0476 0.0777 1
Schistosoma mansoni hypothetical protein 0.1387 0.2342 0.2342
Schistosoma mansoni tubulin subunit beta 0.0476 0.0777 0.0777
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0076 0.0089 0.0225
Loa Loa (eye worm) hypothetical protein 0.0086 0.0106 0.0641
Trypanosoma cruzi beta tubulin, putative 0.0476 0.0777 1
Loa Loa (eye worm) hypothetical protein 0.0548 0.09 0.5583
Trichomonas vaginalis ABC transporter, putative 0.0086 0.0106 0.0875
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0086 0.0106 0.0875
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0008 0.0008
Schistosoma mansoni Smad4 0.005 0.0044 0.0044
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.0084 0.069
Loa Loa (eye worm) multidrug resistance protein 3 0.0086 0.0106 0.0641
Leishmania major cathepsin L-like protease 0.0028 0.0007 0.0033
Echinococcus multilocularis cysteine protease 0.0028 0.0007 0.0007
Trypanosoma brucei importin beta-1 subunit, putative 0.009 0.0113 0.1412
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0036 0.0275
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0028 0.0007 0.0085
Echinococcus multilocularis ATP binding cassette sub family B 0.0027 0.0005 0.0005
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0233 0.036 0.095
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.018 0.0267 0.0267
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0324 0.0515 0.6632
Loa Loa (eye worm) alpha-tubulin 0.0351 0.0561 0.3476
Onchocerca volvulus Netrin receptor homolog 0.0029 0.0008 0.0063
Leishmania major delta tubulin, putative 0.011 0.0148 0.1863
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Trichomonas vaginalis chromobox protein, putative 0.0079 0.0095 0.0782
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0052 0.0047 0.0047
Loa Loa (eye worm) MH1 domain-containing protein 0.005 0.0044 0.0255
Loa Loa (eye worm) tubulin alpha 2 0.024 0.0372 0.2297
Schistosoma mansoni smad1 5 8 and 0.005 0.0044 0.0044
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0086 0.0106 0.0875
Leishmania major beta tubulin 0.0476 0.0777 1
Loa Loa (eye worm) inositol-1 0.0037 0.0022 0.0117
Giardia lamblia Multidrug resistance-associated protein 1 0.0027 0.0005 0.0033
Loa Loa (eye worm) hypothetical protein 0.0116 0.0158 0.0966
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.0078 0.0973
Trypanosoma brucei zeta tubulin 0.011 0.0148 0.1863
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0117 0.0159 0.0159
Onchocerca volvulus 0.0062 0.0064 0.0541
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.0019 0.0198
Echinococcus multilocularis tubulin alpha 1C chain 0.0351 0.0561 0.0561
Loa Loa (eye worm) jmjC domain-containing protein 0.013 0.0182 0.1118
Schistosoma mansoni hypothetical protein 0.0029 0.0008 0.0008
Schistosoma mansoni RAR-like nuclear receptor 0.0062 0.0064 0.0064
Echinococcus multilocularis snurportin 1 0.0961 0.161 0.161
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0076 0.0089 0.1145
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.0078 0.0714
Echinococcus multilocularis tubulin subunit TubB 0.0351 0.0561 0.0561
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0027 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0016
Brugia malayi Pre-SET motif family protein 0.0625 0.1032 0.854
Brugia malayi ABC transporter 0.0027 0.0005 0.0021
Echinococcus granulosus chromobox protein 1 0.0079 0.0095 0.0095
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0008 0.0008
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0004 0.0012
Schistosoma mansoni hypothetical protein 0.0063 0.0067 0.0067
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0324 0.0515 0.9091
Echinococcus multilocularis musashi 0.0085 0.0104 0.0104
Brugia malayi MH1 domain containing protein 0.005 0.0044 0.034
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0318 0.0504 0.3122
Plasmodium falciparum tubulin delta chain, putative 0.011 0.0148 0.1906
Echinococcus multilocularis tubulin alpha chain 0.0351 0.0561 0.0561
Leishmania major beta tubulin 0.0476 0.0777 1
Echinococcus multilocularis smad 0.005 0.0044 0.0044
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0027 0.0005 0.0015
Schistosoma mansoni survival motor neuron protein 0.0112 0.0151 0.0151
Brugia malayi CHE-14 protein 0.0041 0.0029 0.022
Echinococcus multilocularis ATP binding cassette sub family G 0.005 0.0045 0.0045
Echinococcus multilocularis Tubulin beta 2C chain 0.0476 0.0777 0.0777
Loa Loa (eye worm) hypothetical protein 0.0128 0.0178 0.1088
Loa Loa (eye worm) hypothetical protein 0.0207 0.0314 0.1939
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0086 0.0106 0.0875
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0045 0.0036 0.0036
Echinococcus multilocularis tubulin alpha 0.0254 0.0395 0.0395
Schistosoma mansoni multidrug resistance protein 0.0086 0.0106 0.0106
Echinococcus granulosus geminin 0.1387 0.2342 0.2342
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0048 0.0041 0.0525
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0062 0.0064 0.0511
Echinococcus multilocularis tubulin alpha chain 0.0351 0.0561 0.0561
Schistosoma mansoni phd/f-box containing protein 0.0052 0.0048 0.0048
Echinococcus granulosus lysine specific demethylase 5A 0.0204 0.0309 0.0309
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.005 0.0045 0.0527
Trypanosoma cruzi tubulin gamma chain 0.0254 0.0395 0.506
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.007 0.0078 0.0195
Loa Loa (eye worm) hypothetical protein 0.0039 0.0026 0.0145
Onchocerca volvulus 0.0028 0.0007 0.0053
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0061 0.0064 0.0064
Leishmania major epsilon tubulin, putative 0.0254 0.0395 0.506
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0027 0.0005 0.0005
Toxoplasma gondii melibiase subfamily protein 0.0117 0.0159 0.2003
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.006 0.0062 0.05
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0048 0.0041 0.0342
Plasmodium vivax importin-beta 2, putative 0.009 0.0113 0.1456
Echinococcus granulosus JmjC domain containing protein 4 0.0052 0.0048 0.0048
Brugia malayi Protein kinase domain containing protein 0.0029 0.0009 0.005
Loa Loa (eye worm) heterochromatin protein 1 0.0079 0.0095 0.0573
Brugia malayi jmjC domain containing protein 0.0204 0.0309 0.2544
Loa Loa (eye worm) hypothetical protein 0.007 0.0078 0.0469
Schistosoma mansoni inositol monophosphatase 0.0037 0.0022 0.0022
Brugia malayi conserved hypotetical protein 0.0029 0.0008 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0062 0.0064 0.0511
Plasmodium vivax ABC transporter B family member 7, putative 0.0027 0.0005 0.0067
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0223 0.0342 0.0342
Echinococcus multilocularis multidrug resistance associated protein 1 0.0027 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0007 0.0034
Echinococcus granulosus tubulin delta chain 0.011 0.0148 0.0148
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0017 0.0218
Brugia malayi Bromodomain containing protein 0.007 0.0079 0.0635
Trichomonas vaginalis tubulin gamma chain, putative 0.011 0.0148 0.1235
Onchocerca volvulus 0.0029 0.0008 0.0068
Schistosoma mansoni cpg binding protein 0.0068 0.0075 0.0075
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0567 0.0933 0.5791
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.0194 0.0194
Brugia malayi Importin beta-1 subunit 0.009 0.0113 0.0917
Brugia malayi beta-tubulin, identical 0.0476 0.0777 0.6422
Echinococcus multilocularis ATP binding cassette sub family B 0.0027 0.0005 0.0005
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0008 0.0008
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0086 0.0106 0.0875
Schistosoma mansoni jumonji/arid domain-containing protein 0.0204 0.0309 0.0309
Onchocerca volvulus 0.0028 0.0007 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0064 0.0511
Schistosoma mansoni zinc finger protein 0.0046 0.0038 0.0038
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0066 0.0072 0.093
Echinococcus granulosus intermediate filament protein 0.0085 0.0104 0.0104
Onchocerca volvulus 0.0085 0.0104 0.0877
Echinococcus multilocularis FTZ F1 alpha 0.0062 0.0064 0.0064
Loa Loa (eye worm) BEN-1 protein 0.0476 0.0777 0.4818
Loa Loa (eye worm) hypothetical protein 0.0052 0.0048 0.0281
Echinococcus multilocularis thioredoxin glutathione reductase 0.0102 0.0134 0.0134
Brugia malayi Cathepsin L-like precursor 0.0028 0.0007 0.0033
Echinococcus granulosus TNFR CD27 30 40 95 cysteine rich region 0.0044 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0036 0.0282
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.027 0.0422 0.0422
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0045 0.0036 0.021
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0062 0.0064 0.0064
Echinococcus granulosus peregrin 0.007 0.0079 0.0079
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0004 0.0008
Schistosoma mansoni importin beta-1 0.009 0.0113 0.0113
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0142 0.0203 0.0203
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0035 0.0019 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0422 0.3561
Echinococcus multilocularis PHD finger protein rhinoceros 0.0063 0.0067 0.0067
Echinococcus multilocularis cathepsin L cysteine protease 0.0028 0.0007 0.0007
Toxoplasma gondii NADPH-glutathione reductase 0.0035 0.0019 0.0198
Loa Loa (eye worm) hypothetical protein 0.0123 0.017 0.1042
Echinococcus multilocularis lipoxygenase domain containing protein 0.0122 0.0167 0.0167
Trypanosoma brucei epsilon tubulin 0.0254 0.0395 0.506
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0017 0.0122
Echinococcus granulosus expressed conserved protein 0.009 0.0113 0.0113
Schistosoma mansoni patched 1 0.0041 0.0029 0.0029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.035 0.035
Trypanosoma cruzi alpha tubulin, putative 0.0351 0.0561 0.721
Schistosoma mansoni steroid hormone receptor ad4bp 0.0062 0.0064 0.0064
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0062 0.0064 0.0383
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0324 0.0515 0.0515
Brugia malayi F/Y-rich N-terminus family protein 0.0048 0.004 0.0312
Trypanosoma cruzi zeta tubulin, putative 0.011 0.0148 0.1863
Entamoeba histolytica P-glycoprotein-2 0.0086 0.0106 0.1331
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0383
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0046 0.0367
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0072 0.0081 0.0081
Trichomonas vaginalis ABC transporter, putative 0.0086 0.0106 0.0875
Echinococcus multilocularis ubiquitin specific protease 41 0.0045 0.0036 0.0036
Echinococcus granulosus death domain containing protein 0.0029 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0036
Toxoplasma gondii ABC transporter, putative 0.0027 0.0005 0.0015
Echinococcus multilocularis Tubulin beta 2C chain 0.0476 0.0777 0.0777
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0036
Entamoeba histolytica P-glycoprotein 5, putative 0.0086 0.0106 0.1331
Trichomonas vaginalis importin beta-1, putative 0.0073 0.0084 0.069
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0026 0.0003 0.0005
Echinococcus multilocularis tubulin epsilon chain 0.0254 0.0395 0.0395
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0041 0.0476
Echinococcus granulosus ubiquitin specific protease 41 0.0045 0.0036 0.0036
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0086 0.0106 0.0106
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0109 0.0145 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0086 0.1065
Plasmodium falciparum ABC transporter B family member 3, putative 0.0027 0.0005 0.0067
Leishmania major alpha tubulin 0.0351 0.0561 0.721
Brugia malayi photoreceptor-specific nuclear receptor 0.0062 0.0064 0.0511
Brugia malayi nuclear hormone receptor 0.0029 0.0008 0.0048
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.018 0.0267 0.0267
Trichomonas vaginalis ABC transporter, putative 0.0086 0.0106 0.0875
Echinococcus multilocularis tubulin alpha chain 0.0351 0.0561 0.0561
Echinococcus granulosus tubulin alpha chain 0.0351 0.0561 0.0561
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0086 0.0106 0.0875
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.005 0.0045 0.0045
Entamoeba histolytica ATP-binding cassette protein, putative 0.0027 0.0005 0.0033
Loa Loa (eye worm) hypothetical protein 0.0084 0.0103 0.0625
Giardia lamblia Alpha-tubulin 0.0351 0.0561 0.7215
Schistosoma mansoni multidrug resistance protein 0.0086 0.0106 0.0106
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0062 0.0064 0.0383
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0324 0.0515 0.0515
Echinococcus granulosus Tubulin alpha 1 chain 0.0351 0.0561 0.0561
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0004 0.0052
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0008 0.0048
Trypanosoma cruzi multidrug resistance protein E, putative 0.0027 0.0005 0.0015
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0014 0.0014
Echinococcus granulosus lysine specific demethylase 6a 0.0052 0.0048 0.0048
Brugia malayi Tubulin alpha-2 chain 0.0351 0.0561 0.4633
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0033
Brugia malayi follicle stimulating hormone receptor 0.0248 0.0384 0.3166
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0086 0.1065
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0036 0.0411
Echinococcus granulosus tubulin alpha chain 0.0351 0.0561 0.0561
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0027 0.0005 0.0015
Brugia malayi Nuclear hormone receptor-like 1 0.0062 0.0064 0.0511
Plasmodium falciparum multidrug resistance-associated protein 1 0.0027 0.0005 0.0067
Loa Loa (eye worm) hypothetical protein 0.0033 0.0014 0.0073
Entamoeba histolytica hypothetical protein 0.0223 0.0342 0.438
Echinococcus multilocularis tubulin alpha 3 chain 0.0351 0.0561 0.0561
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.018 0.0267 0.0267
Leishmania major beta tubulin 0.0476 0.0777 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0085 0.0104 0.063
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0027 0.0005 0.0015
Brugia malayi CXXC zinc finger family protein 0.0059 0.0059 0.0468
Leishmania major gamma-tubulin 0.0254 0.0395 0.506
Plasmodium falciparum thioredoxin reductase 0.0035 0.0019 0.0249
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0019 0.0198
Trichomonas vaginalis ran, putative 0.0066 0.0072 0.0592
Brugia malayi ABC transporter family protein 0.0043 0.0032 0.0243
Trichomonas vaginalis abcb9, putative 0.0086 0.0106 0.0875
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0062 0.0064 0.0383
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0565 0.4774
Trichomonas vaginalis mercuric reductase, putative 0.0035 0.0019 0.0142
Brugia malayi Papain family cysteine protease containing protein 0.0028 0.0007 0.0033
Loa Loa (eye worm) hypothetical protein 0.0039 0.0026 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0035 0.0274
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0008 0.0008
Giardia lamblia ABC transporter 0.0049 0.0042 0.0511
Loa Loa (eye worm) intermediate filament protein 0.0085 0.0104 0.063
Brugia malayi Cathepsin L-like precursor 0.0028 0.0007 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0148 0.1235
Trypanosoma brucei trypanothione reductase 0.0102 0.0134 0.1685
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0066 0.0072 0.0883
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0027 0.0005 0.0015
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.0255 0.0669
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0008 0.0008
Leishmania major beta tubulin 0.0476 0.0777 1
Schistosoma mansoni tubulin subunit beta 0.0476 0.0777 0.0777
Schistosoma mansoni lipoxygenase 0.0508 0.0832 0.0832
Schistosoma mansoni tar DNA-binding protein 0.0318 0.0504 0.0504
Loa Loa (eye worm) tubulin alpha 2 0.024 0.0372 0.2297
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0086 0.1065
Loa Loa (eye worm) hypothetical protein 0.0064 0.0068 0.0406
Loa Loa (eye worm) steroid hormone receptor 0.0062 0.0064 0.0383
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0036
Giardia lamblia Alpha-tubulin 0.0351 0.0561 0.7215
Trichomonas vaginalis tubulin beta chain, putative 0.0351 0.0561 0.4743
Loa Loa (eye worm) hypothetical protein 0.0122 0.0167 0.1024
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.0051 0.0607
Leishmania major beta tubulin 0.0476 0.0777 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0072 0.0081 0.0081
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0036 0.0036
Brugia malayi tubulin alpha-2 chain 0.0351 0.0561 0.4633
Echinococcus granulosus Tubulin beta 2C chain 0.0476 0.0777 0.0777
Brugia malayi Probable ClpP-like protease 0.0324 0.0515 0.4252
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0027 0.0005 0.0015
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0017 0.0186
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0086 0.0106 0.0875
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0028 0.0007 0.0085
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0035 0.0019 0.0198
Schistosoma mansoni rab6-interacting 0.0122 0.0167 0.0167
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0028 0.0007 0.0025
Brugia malayi Isocitrate dehydrogenase 0.0048 0.0041 0.0317
Plasmodium vivax vivapain-2 0.0028 0.0007 0.0085
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0036
Schistosoma mansoni tar DNA-binding protein 0.0318 0.0504 0.0504
Echinococcus multilocularis Tubulin alpha 1 chain 0.0351 0.0561 0.0561
Echinococcus multilocularis Tubulin alpha 1 chain 0.0351 0.0561 0.0561
Schistosoma mansoni polycystin 1-related 0.0122 0.0167 0.0167
Schistosoma mansoni zinc finger protein 0.0029 0.0008 0.0008
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0027 0.0005 0.0067
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0324 0.0515 0.6615
Brugia malayi nuclear receptor RXR 0.0033 0.0014 0.0097
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.062 0.1024 0.2733
Schistosoma mansoni smad1 5 8 and 0.005 0.0044 0.0044
Leishmania major beta tubulin 0.0476 0.0777 1
Schistosoma mansoni smad1 5 8 and 0.005 0.0044 0.0044
Plasmodium falciparum flap endonuclease 1 0.0027 0.0004 0.0052
Echinococcus granulosus peptidase Clp S14 family 0.0212 0.0323 0.0323
Loa Loa (eye worm) glutathione reductase 0.0102 0.0134 0.0819
Trypanosoma brucei ATP-binding cassette protein, putative 0.005 0.0045 0.0527
Brugia malayi Cathepsin L-like precursor 0.0028 0.0007 0.0033
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0324 0.0515 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.0019 0.0198
Echinococcus granulosus Polycystic kidney disease protein 0.0122 0.0167 0.0167
Entamoeba histolytica tubulin family protein 0.0476 0.0777 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0233 0.036 0.095
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0035 0.0019 0.0019
Echinococcus multilocularis importin subunit beta 1 0.009 0.0113 0.0113
Leishmania major beta tubulin 0.0476 0.0777 1
Brugia malayi hypothetical protein 0.0029 0.0008 0.0048
Plasmodium falciparum LCCL domain-containing protein 0.0122 0.0167 0.2152
Echinococcus granulosus thymidine phosphorylase 0.2197 0.3733 0.3733
Brugia malayi nuclear receptor NHR-88 0.0062 0.0064 0.0511
Echinococcus granulosus multidrug resistance associated protein 7 0.0027 0.0005 0.0005
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0086 0.0106 0.0875
Echinococcus multilocularis ATP binding cassette sub family G 0.005 0.0045 0.0045
Brugia malayi ABC transporter family protein 0.0027 0.0005 0.0021
Loa Loa (eye worm) nuclear factor I 0.0027 0.0006 0.0018
Trichomonas vaginalis tubulin beta chain, putative 0.0351 0.0561 0.4743
Trypanosoma cruzi trypanothione reductase, putative 0.0102 0.0134 0.1685
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0076 0.0089 0.1145
Trichomonas vaginalis set domain proteins, putative 0.0711 0.118 1
Echinococcus multilocularis netrin receptor unc 5 0.0029 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0112 0.0151 0.0151
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0177 0.0177
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.0019 0.0278
Echinococcus multilocularis tubulin beta 1 chain 0.0476 0.0777 0.0777
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0064 0.0511
Plasmodium falciparum cysteine proteinase falcipain 3 0.0028 0.0007 0.0085
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0007 0.0034
Plasmodium vivax tubulin beta chain, putative 0.0476 0.0777 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0036 0.0429
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0043 0.0101
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.035 0.035
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0062 0.0064 0.0064
Leishmania major beta tubulin 0.0476 0.0777 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0052 0.0048 0.0048
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0035 0.0019 0.0038
Loa Loa (eye worm) hypothetical protein 0.0033 0.0014 0.0073
Echinococcus granulosus mothers against decapentaplegic 5 0.005 0.0044 0.0044
Echinococcus granulosus tumor necrosis factor receptor superfamily 0.0044 0.0034 0.0034
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0324 0.0515 1
Plasmodium falciparum alpha tubulin 2 0.0351 0.0561 0.7224
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0046 0.0558
Plasmodium falciparum cysteine proteinase falcipain 1 0.012 0.0164 0.2114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0086 0.1065
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0062 0.0064 0.0779
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0035 0.0019 0.0249
Plasmodium falciparum ABC transporter B family member 4, putative 0.0027 0.0005 0.0067
Echinococcus multilocularis protein dispatched 1 0.0047 0.0039 0.0039
Echinococcus granulosus GTP binding nuclear protein Ran 0.0066 0.0072 0.0072
Entamoeba histolytica hypothetical protein 0.0073 0.0084 0.105
Trichomonas vaginalis glutathione reductase, putative 0.0035 0.0019 0.0142
Loa Loa (eye worm) hypothetical protein 0.0033 0.0014 0.0073
Loa Loa (eye worm) hypothetical protein 0.0122 0.0167 0.1024
Entamoeba histolytica ATP-binding cassette protein, putative 0.0027 0.0005 0.0033
Schistosoma mansoni TGF-beta signal transducer Smad2 0.005 0.0044 0.0044
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0026 0.0003 0.0003
Trypanosoma cruzi ATP-binding cassette protein, putative 0.005 0.0045 0.0527
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0008 0.0008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0172 0.0254 0.0668
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0035 0.0019 0.0038
Trypanosoma brucei tubulin gamma chain 0.0254 0.0395 0.506
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0327 0.052 0.6679
Echinococcus granulosus Tubulin alpha 1 chain 0.0351 0.0561 0.0561
Trichomonas vaginalis tubulin epsilon chain, putative 0.0476 0.0777 0.6574
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0022 0.0226
Brugia malayi jmjC domain containing protein 0.0052 0.0048 0.0375
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0259 0.0404 0.107
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.0008 0.0008
Brugia malayi Tubulin alpha chain 0.011 0.0148 0.1206
Echinococcus granulosus snurportin 1 0.0961 0.161 0.161
Entamoeba histolytica P-glycoprotein 6, putative 0.0027 0.0005 0.0033
Brugia malayi Pre-SET motif family protein 0.0091 0.0114 0.0927
Echinococcus granulosus Tubulin beta 2C chain 0.0476 0.0777 0.0777
Trypanosoma brucei alpha tubulin 0.0351 0.0561 0.721
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0086 0.0106 0.1314
Schistosoma mansoni peptidase Clp (S14 family) 0.0324 0.0515 0.0515
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0062 0.0064 0.0064
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.0255 0.2449
Trypanosoma brucei ABC transporter, putative 0.005 0.0045 0.0527
Giardia lamblia DNA repair protein RAD52 0.0354 0.0567 0.7288
Schistosoma mansoni ran 0.0066 0.0072 0.0072
Schistosoma mansoni transcription factor LCR-F1 0.0223 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.007 0.0078 0.0469
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0022 0.0022
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0123 0.1558
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0078 0.0195
Loa Loa (eye worm) tubulin alpha-3 chain 0.0207 0.0314 0.1939
Brugia malayi Tubulin beta-1 chain 0.0476 0.0777 0.6422
Schistosoma mansoni hypothetical protein 0.0207 0.0314 0.0314
Echinococcus granulosus tubulin alpha 3 chain 0.0351 0.0561 0.0561
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.005 0.0045 0.0106
Echinococcus granulosus multidrug resistance protein 1 0.006 0.0062 0.0062
Schistosoma mansoni multidrug resistance protein 0.0027 0.0005 0.0005
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0036 0.0036
Schistosoma mansoni alpha tubulin 0.0351 0.0561 0.0561
Echinococcus multilocularis multidrug resistance associated protein 7 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0052 0.0048 0.0282
Echinococcus granulosus tubulin alpha 0.0254 0.0395 0.0395
Onchocerca volvulus Cathepsin F homolog 0.0028 0.0007 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0062 0.0064 0.0511
Brugia malayi Smad1 0.005 0.0044 0.034
Mycobacterium ulcerans hypothetical protein 0.0172 0.0254 0.0668
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0051 0.0607
Echinococcus multilocularis tubulin alpha 3 chain 0.0351 0.0561 0.0561
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0008 0.0043
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0086 0.0106 0.0106
Echinococcus granulosus dnaJ subfamily B 0.0833 0.139 0.139
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0052 0.0048 0.0567
Echinococcus multilocularis protein patched 0.0041 0.0029 0.0029
Brugia malayi chromobox protein homolog 3 0.0044 0.0035 0.0268
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0064 0.0511
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0263 0.2208
Brugia malayi hypothetical protein 0.0223 0.0342 0.2813
Echinococcus granulosus Ankyrin 0.0029 0.0008 0.0008
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0086 0.0106 0.0106
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0022 0.0226
Brugia malayi N-terminal motif family protein 0.0183 0.0273 0.224
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0046 0.054
Schistosoma mansoni rab6-interacting 0.0122 0.0167 0.0167
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0027 0.0005 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0064 0.0064
Echinococcus granulosus chromobox protein 1 0.0079 0.0095 0.0095
Trichomonas vaginalis taga, putative 0.0086 0.0106 0.0875
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.0019 0.0198
Echinococcus granulosus multidrug resistance protein 1 0.006 0.0062 0.0062
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0027 0.0005 0.0067
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0036 0.0411
Echinococcus granulosus peroxisome assembly protein 26 0.0351 0.0561 0.0561
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0062 0.0064 0.0383
Trypanosoma brucei zeta tubulin, putative 0.011 0.0148 0.1863
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0028 0.0007 0.0007
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0086 0.0106 0.0875
Onchocerca volvulus Glucosylceramidase homolog 0.0177 0.0263 0.2223
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0007 0.0034
Echinococcus granulosus phd:f box containing protein 0.0052 0.0048 0.0048
Schistosoma mansoni alpha tubulin 0.0351 0.0561 0.0561
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.0019 0.0198
Brugia malayi PHD-finger family protein 0.003 0.001 0.0058
Echinococcus multilocularis Tubulin beta 2C chain 0.0476 0.0777 0.0777
Onchocerca volvulus 0.0122 0.0167 0.1414
Echinococcus multilocularis tubulin subunit beta 0.0476 0.0777 0.0777
Brugia malayi latrophilin 2 splice variant baaae 0.0388 0.0625 0.516
Trichomonas vaginalis tubulin gamma chain, putative 0.0254 0.0395 0.3333
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0066 0.0072 0.0883
Schistosoma mansoni tubulin subunit alpha 0.0351 0.0561 0.0561
Plasmodium falciparum glutathione reductase 0.0035 0.0019 0.0249
Schistosoma mansoni ankyrin 23/unc44 0.0029 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0165
Brugia malayi steroid hormone receptor 0.0062 0.0064 0.0511
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0027 0.0005 0.0015
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0066 0.0072 0.0883
Brugia malayi Flap endonuclease-1 0.0027 0.0004 0.0012
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0022 0.0044
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0062 0.0064 0.0064
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.011 0.0148 0.1863
Plasmodium vivax ABC transporter B family member 5, putative 0.0027 0.0005 0.0067
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0041 0.0476
Schistosoma mansoni tubulin subunit alpha 0.0351 0.0561 0.0561
Echinococcus granulosus RUN 0.0122 0.0167 0.0167
Plasmodium falciparum acyl-CoA synthetase 0.0052 0.0048 0.0614
Echinococcus multilocularis expressed conserved protein 0.009 0.0113 0.0113
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.006 0.0146
Trypanosoma brucei beta tubulin 0.0476 0.0777 1
Loa Loa (eye worm) tubulin beta chain 0.0476 0.0777 0.4818
Echinococcus granulosus ATP binding cassette sub family B 0.0026 0.0003 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0043 0.0101
Echinococcus multilocularis tumor necrosis factor receptor superfamily 0.0044 0.0034 0.0034
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0301 0.0476 0.3925
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0019 0.0198
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0383
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0048 0.0041 0.0096
Echinococcus granulosus fetal alzheimer antigen falz 0.0072 0.0081 0.0081
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0076 0.0089 0.1275
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0062 0.0064 0.0383
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0062 0.0064 0.0064
Loa Loa (eye worm) BEN-1 protein 0.0476 0.0777 0.4818
Brugia malayi hypothetical protein 0.0033 0.0014 0.0097
Plasmodium falciparum JmjC domain-containing protein, putative 0.0052 0.0048 0.0616
Toxoplasma gondii beta-1 tubulin, putative 0.0476 0.0777 1
Brugia malayi hypothetical protein 0.0035 0.0018 0.0129
Echinococcus granulosus jumonji domain containing protein 0.0088 0.0109 0.0109
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0086 0.0106 0.0875
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0052 0.0048 0.0281
Plasmodium falciparum tubulin beta chain 0.0476 0.0777 1
Giardia lamblia Delta tubulin 0.011 0.0148 0.1879
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0565 0.4774
Leishmania major alpha tubulin 0.0351 0.0561 0.721
Loa Loa (eye worm) ABC transporter 0.0027 0.0005 0.0016
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0155 0.0224 0.285
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0029 0.0165
Schistosoma mansoni jumonji/arid domain-containing protein 0.0204 0.0309 0.0309
Schistosoma mansoni hypothetical protein 0.018 0.0267 0.0267
Entamoeba histolytica ATP-binding cassette protein, putative 0.0027 0.0005 0.0033
Brugia malayi MH2 domain containing protein 0.005 0.0044 0.034
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0046 0.0046
Loa Loa (eye worm) tubulin alpha 2 0.0097 0.0125 0.0759
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0052 0.0048 0.0114
Schistosoma mansoni cathepsin F (C01 family) 0.0028 0.0007 0.0007
Echinococcus granulosus cathepsin L cysteine proteinase 0.0028 0.0007 0.0007
Echinococcus granulosus beta tubulin 0.0476 0.0777 0.0777
Onchocerca volvulus Cathepsin L homolog 0.0028 0.0007 0.0053
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.006 0.0146
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0059 0.006 0.006
Echinococcus multilocularis RUN 0.0122 0.0167 0.0167
Entamoeba histolytica ABC transporter, putative 0.0027 0.0005 0.0033
Trichomonas vaginalis tubulin gamma chain, putative 0.0254 0.0395 0.3333
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0123 0.0123
Loa Loa (eye worm) ABC transporter 0.0027 0.0005 0.0016
Entamoeba histolytica P-glycoprotein 6, putative 0.0027 0.0005 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0038 0.0432
Plasmodium vivax vivapain-2 0.0028 0.0007 0.0085
Schistosoma mansoni hypothetical protein 0.0046 0.0038 0.0038
Schistosoma mansoni multidrug resistance protein 0.0026 0.0003 0.0003
Toxoplasma gondii beta tubulin 0.0476 0.0777 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0017 0.0168
Brugia malayi Calcitonin receptor-like protein seb-1 0.0567 0.0933 0.7718
Schistosoma mansoni lamin 0.0085 0.0104 0.0104
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0092 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0017 0.0122
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0008 0.0036
Toxoplasma gondii histone lysine methyltransferase SET1 0.0121 0.0167 0.2107
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0254 0.0395 0.506
Onchocerca volvulus 0.0028 0.0007 0.0053
Trypanosoma cruzi cruzipain precursor, putative 0.0074 0.0086 0.1065
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0008 0.0008
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0035 0.0292
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0036 0.0282
Brugia malayi ABC transporter transmembrane region family protein 0.0027 0.0005 0.0021
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0004 0.0019
Loa Loa (eye worm) hypothetical protein 0.0132 0.0186 0.114
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0029 0.0008 0.0033
Schistosoma mansoni ran 0.0066 0.0072 0.0072
Entamoeba histolytica tubulin alpha-1 chain 0.0351 0.0561 0.7215
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0036 0.0282
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0067 0.086
Mycobacterium tuberculosis Probable oxidoreductase 0.0259 0.0404 0.107
Schistosoma mansoni hypothetical protein 0.1387 0.2342 0.2342
Brugia malayi MH1 domain containing protein 0.005 0.0044 0.034
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0045 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0388 0.0625 0.0625
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0036
Echinococcus granulosus tar DNA binding protein 0.0318 0.0504 0.0504
Loa Loa (eye worm) hypothetical protein 0.027 0.0422 0.2612
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0565 0.4774
Echinococcus multilocularis multidrug resistance protein 1 0.0086 0.0106 0.0106
Toxoplasma gondii PHD-finger domain-containing protein 0.0063 0.0067 0.0813
Onchocerca volvulus 0.0122 0.0167 0.1414
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0019 0.0198
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0062 0.0064 0.0064
Schistosoma mansoni jumonji domain containing protein 0.0052 0.0048 0.0048
Echinococcus multilocularis chromobox protein 1 0.0079 0.0095 0.0095
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0046 0.054
Brugia malayi jmjC domain containing protein 0.0052 0.0048 0.0375
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0046 0.054
Brugia malayi tailless protein 0.0029 0.0008 0.0048
Echinococcus multilocularis ecdysone induced protein 78C 0.0062 0.0064 0.0064
Echinococcus granulosus L aminoadipate semialdehyde 0.027 0.0422 0.0422
Brugia malayi Cathepsin L-like precursor 0.0028 0.0007 0.0033
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0383
Leishmania major alpha tubulin 0.0351 0.0561 0.721
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0008 0.0048
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0048 0.0041 0.0041
Echinococcus multilocularis L aminoadipate semialdehyde 0.027 0.0422 0.0422
Trypanosoma cruzi tubulin delta chain 0.011 0.0148 0.1863
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0027 0.0005 0.0015
Leishmania major hypothetical protein, conserved 0.0054 0.0051 0.0607
Plasmodium falciparum ABC transporter B family member 6, putative 0.0027 0.0005 0.0067
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0035 0.0019 0.0249
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0184 0.0274 0.0274
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0035 0.0019 0.0038
Loa Loa (eye worm) ABC transporter 0.0043 0.0032 0.0182
Echinococcus multilocularis Ankyrin 0.0029 0.0008 0.0008
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0027 0.0005 0.0015
Brugia malayi ABC transporter family protein 0.0086 0.0106 0.0854
Loa Loa (eye worm) thioredoxin reductase 0.0102 0.0134 0.0819
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0109 0.0145 0.0145
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0022 0.016
Echinococcus multilocularis lamin dm0 0.0085 0.0104 0.0104
Echinococcus granulosus histone lysine methyltransferase setb 0.0142 0.0203 0.0203
Leishmania major beta tubulin 0.0476 0.0777 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Echinococcus multilocularis tubulin alpha chain 0.0351 0.0561 0.0561
Mycobacterium ulcerans hypothetical protein 0.007 0.0078 0.0195
Echinococcus granulosus flap endonuclease 1 0.0027 0.0004 0.0004
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0041 0.0476
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.007 0.0078 0.0195
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0036 0.0411
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0004 0.0008
Entamoeba histolytica hypothetical protein 0.0034 0.0017 0.0186
Echinococcus granulosus Tubulin beta 2C chain 0.0476 0.0777 0.0777
Echinococcus granulosus tubulin alpha chain 0.0351 0.0561 0.0561
Leishmania major GTP-binding protein, putative 0.0066 0.0072 0.0883
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.0565 0.7262
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0027 0.0005 0.0015
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0059 0.006 0.0146
Schistosoma mansoni nuclear receptor 0.0029 0.0008 0.0008
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0259 0.0404 0.107
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0046 0.0046
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0027 0.0005 0.0015
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0027 0.0005 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0233 0.036 0.095
Entamoeba histolytica P-glycoprotein-2 0.0086 0.0106 0.1331
Brugia malayi hypothetical protein 0.0336 0.0535 0.4416
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0056 0.0055 0.0656
Schistosoma mansoni multidrug resistance protein 0.0027 0.0005 0.0005
Trypanosoma brucei alpha tubulin 0.0351 0.0561 0.721
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0022 0.0319
Echinococcus multilocularis ATP binding cassette sub family G 0.005 0.0045 0.0045
Echinococcus multilocularis jumonji domain containing 1A 0.0052 0.0048 0.0048
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0008 0.0036
Trichomonas vaginalis abcb9, putative 0.0086 0.0106 0.0875
Brugia malayi Bromodomain containing protein 0.023 0.0354 0.2913
Leishmania major cathepsin L-like protease 0.0074 0.0086 0.1065
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0007 0.0034
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0324 0.0515 0.1368
Entamoeba histolytica tubulin gamma chain 0.0254 0.0395 0.507
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0062 0.0064 0.0064
Plasmodium falciparum phd finger protein, putative 0.0063 0.0067 0.086
Brugia malayi PHD-finger family protein 0.0079 0.0094 0.0755
Echinococcus multilocularis JmjC domain containing protein 4 0.0052 0.0048 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0104 0.0137 0.0137
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0066 0.0072 0.093
Schistosoma mansoni tubulin subunit gamma 0.0254 0.0395 0.0395
Brugia malayi P-glycoprotein-like protein 0.0027 0.0005 0.0021
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0086 0.0106 0.0875
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0086 0.1065
Echinococcus granulosus importin subunit beta 1 0.009 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0052 0.0048 0.0282
Echinococcus granulosus FTZ F1 alpha 0.0062 0.0064 0.0064
Leishmania major alpha tubulin 0.0351 0.0561 0.721
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0027 0.0005 0.0022
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.062 0.1024 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0036
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0046 0.054
Schistosoma mansoni lipoxygenase 0.0727 0.1207 0.1207
Echinococcus multilocularis geminin 0.1387 0.2342 0.2342
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0035 0.0019 0.0198
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0117 0.0159 0.0159
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0007 0.0034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0004 0.0008
Entamoeba histolytica multidrug resistance protein, putative 0.0027 0.0005 0.0033
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0008 0.0008
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0212 0.0323 0.3124
Leishmania major cathepsin L-like protease 0.0028 0.0007 0.0033
Mycobacterium leprae conserved hypothetical protein 0.0076 0.0089 0.0822
Mycobacterium leprae cell division protein FtsZ 0.011 0.0148 0.1402
Brugia malayi jmjC domain containing protein 0.0052 0.0048 0.0375
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0029 0.0029
Brugia malayi Thioredoxin reductase 0.0102 0.0134 0.1092
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0007 0.0034
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0159 0.0159
Brugia malayi hypothetical protein 0.0027 0.0005 0.0021
Brugia malayi Bromodomain containing protein 0.0116 0.0158 0.1284
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0035 0.0019 0.0019
Leishmania major hypothetical protein, conserved 0.0046 0.0038 0.0439
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0112 0.015 0.1934
Trichomonas vaginalis tubulin beta chain, putative 0.0351 0.0561 0.4743
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0048 0.0041 0.0476
Plasmodium vivax tubulin alpha chain, putative 0.0351 0.0561 0.7224
Loa Loa (eye worm) beta-tubulin 0.0476 0.0777 0.4818
Echinococcus granulosus TGF beta signal transducer SmadC 0.005 0.0044 0.0044
Echinococcus granulosus lipoxygenase domain containing protein 0.0122 0.0167 0.0167
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0086 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0096 0.0123 0.0751
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0279 0.2347
Leishmania major alpha tubulin 0.0351 0.0561 0.721
Brugia malayi hypothetical protein 0.0122 0.0167 0.1365
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0028 0.0007 0.0025
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0076 0.0089 0.1099
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0263 0.2208
Entamoeba histolytica hypothetical protein 0.0223 0.0342 0.438
Loa Loa (eye worm) tubulin beta chain 0.011 0.0148 0.0905
Schistosoma mansoni hypothetical protein 0.0041 0.0029 0.0029
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0086 0.0106 0.0106
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0086 0.0106 0.0875
Schistosoma mansoni alpha tubulin 0.0351 0.0561 0.0561
Brugia malayi ecdysone receptor 0.0029 0.0008 0.0048
Trypanosoma brucei epsilon tubulin 0.0254 0.0395 0.506
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0114 0.0114
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0027 0.0005 0.0016
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0086 0.0106 0.0875
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0625 0.1032 0.6408
Echinococcus granulosus GPCR family 2 0.018 0.0267 0.0267
Schistosoma mansoni hypothetical protein 0.018 0.0267 0.0267
Loa Loa (eye worm) MH2 domain-containing protein 0.005 0.0044 0.0255
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0027 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.0018
Brugia malayi RNA binding protein 0.0318 0.0504 0.4161
Brugia malayi Intermediate filament tail domain containing protein 0.0085 0.0104 0.084
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0102 0.0134 0.0346
Brugia malayi ecdysteroid receptor 0.0062 0.0064 0.0511
Trypanosoma cruzi importin beta-1 subunit, putative 0.0073 0.0084 0.1033
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0078 0.0195
Echinococcus granulosus tumor protein p63 0.0399 0.0643 0.0643
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0114 0.1428
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0064 0.0064
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0046 0.0269
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0008 0.0008
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.0051 0.0601
Brugia malayi tubulin alpha chain - mouse 0.0351 0.0561 0.4633
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0086 0.0106 0.0875
Echinococcus multilocularis peregrin 0.007 0.0079 0.0079
Echinococcus granulosus neuropeptide receptor A26 0.1982 0.3363 0.3363
Leishmania major basic transcription factor 3a, putative 0.0034 0.0017 0.0168
Schistosoma mansoni intermediate filament proteins 0.0085 0.0104 0.0104
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0007 0.0052
Brugia malayi Inositol-1 0.0037 0.0022 0.0156
Onchocerca volvulus 0.0086 0.0106 0.0892
Schistosoma mansoni nuclear hormone receptor 0.0062 0.0064 0.0064
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.007 0.0078 0.0195
Schistosoma mansoni cpg binding protein 0.0068 0.0075 0.0075
Leishmania major phosphopantetheinyl transferase-like protein 0.0076 0.0089 0.1099
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0263 0.2208
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0047 0.0047
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0029 0.0029
Plasmodium vivax ABC transporter G family member 2, putative 0.005 0.0045 0.0576
Echinococcus granulosus tubulin subunit TubB 0.0351 0.0561 0.0561
Brugia malayi nuclear hormone receptor 0.0062 0.0064 0.0511
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.035 0.035
Brugia malayi Tubulin beta chain 0.011 0.0148 0.1206
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0076 0.0089 0.0225
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0048 0.0041 0.0525
Schistosoma mansoni bromodomain containing protein 0.0195 0.0293 0.0293
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0046 0.0046
Loa Loa (eye worm) jmjC domain-containing protein 0.0052 0.0048 0.0282
Brugia malayi alpha-tubulin 0.0351 0.0561 0.4633
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0035 0.0019 0.0139
Plasmodium falciparum multidrug resistance-associated protein 2 0.0027 0.0005 0.0067
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0048 0.0041 0.0041
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0086 0.0106 0.0875
Onchocerca volvulus 0.007 0.0078 0.0658
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0028 0.0007 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0062 0.0064 0.0511
Echinococcus multilocularis cysteine protease 0.0028 0.0007 0.0007
Leishmania major cathepsin L-like protease 0.0028 0.0007 0.0033
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0014 0.0097
Leishmania major p-glycoprotein e 0.0027 0.0005 0.0015
Brugia malayi nuclear receptor NHR-88 0.0029 0.0008 0.0048
Echinococcus granulosus tubulin alpha 3 chain 0.0351 0.0561 0.0561
Brugia malayi MH2 domain containing protein 0.0727 0.1208 1
Echinococcus granulosus lamin dm0 0.0085 0.0104 0.0104
Onchocerca volvulus 0.027 0.0422 0.3576
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0028 0.0007 0.0034
Schistosoma mansoni cpg binding protein 0.0059 0.0059 0.0059
Echinococcus multilocularis GPCR, family 2 0.018 0.0267 0.0267
Echinococcus granulosus zinc finger protein 0.0063 0.0066 0.0066
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0086 0.0106 0.1314
Echinococcus granulosus multidrug resistance protein 1 0.0086 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0033 0.0014 0.0073
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0029 0.0029
Echinococcus multilocularis tumor protein p63 0.0399 0.0643 0.0643
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0035 0.0019 0.0198
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0007 0.0033
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0029 0.0008 0.0008
Schistosoma mansoni chromobox protein 0.0079 0.0095 0.0095
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0062 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0016
Leishmania major mitochondrial DNA polymerase beta 0.0327 0.052 0.6679
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.011 0.0147 0.0147
Onchocerca volvulus 0.0028 0.0007 0.0053
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0036
Schistosoma mansoni zinc finger protein 0.0063 0.0066 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0046 0.0367
Brugia malayi AMP-binding enzyme family protein 0.007 0.0078 0.0625
Echinococcus granulosus Tubulin beta 2C chain 0.0476 0.0777 0.0777
Echinococcus multilocularis chromobox protein 1 0.0079 0.0095 0.0095
Plasmodium falciparum tubulin epsilon chain, putative 0.0254 0.0395 0.5086
Echinococcus granulosus ecdysone induced protein 78C 0.0062 0.0064 0.0064
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0027 0.0005 0.0015
Brugia malayi multidrug resistance related protein 1 0.0027 0.0005 0.0021
Brugia malayi jmjC domain containing protein 0.0052 0.0048 0.0375
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.011 0.0148 0.1863
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0027 0.0005 0.0015
Echinococcus granulosus tubulin alpha 1C chain 0.0351 0.0561 0.0561
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0325 0.0518 0.0518
Brugia malayi nuclear receptor NHR-67 0.0029 0.0008 0.0048
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.035 0.035
Plasmodium vivax delta tubulin, putative 0.011 0.0148 0.1906
Loa Loa (eye worm) ABC transporter 0.0027 0.0005 0.0016
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0064 0.0064
Giardia lamblia MRP-like ABC transporter 0.0027 0.0005 0.0033
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0228 0.035 0.288
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0422 0.3561
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0007 0.0034
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0727 0.1207 0.1207
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0036
Toxoplasma gondii beta-tubulin, putative 0.0476 0.0777 1
Brugia malayi PHD-finger family protein 0.0063 0.0067 0.0533
Trypanosoma brucei multidrug resistance protein E 0.0027 0.0005 0.0015
Trypanosoma brucei alpha tubulin 0.0351 0.0561 0.721
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.035 0.035
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.0019 0.0278
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0162
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0041 0.0323
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0008 0.0048
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0041 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0008 0.0036
Echinococcus multilocularis ATP binding cassette sub family B 0.0084 0.0103 0.0103
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0035 0.0019 0.0019
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0101 0.0132 0.1666
Entamoeba histolytica hypothetical protein 0.0076 0.0089 0.1115
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0062 0.0064 0.0511
Mycobacterium tuberculosis Probable dehydrogenase 0.0233 0.036 0.095
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0062 0.0064 0.0541
Loa Loa (eye worm) hypothetical protein 0.0028 0.0007 0.0025
Schistosoma mansoni tubulin subunit beta 0.011 0.0148 0.0148
Trichomonas vaginalis tubulin alpha chain, putative 0.0476 0.0777 0.6574
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0008 0.0008
Loa Loa (eye worm) tubulin alpha-2 chain 0.0351 0.0561 0.3476
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0383
Loa Loa (eye worm) hypothetical protein 0.018 0.0267 0.1644
Loa Loa (eye worm) hypothetical protein 0.0086 0.0106 0.0641
Plasmodium vivax unspecified product 0.012 0.0164 0.2114
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.0078 0.0973
Loa Loa (eye worm) ctsf protein 0.0028 0.0007 0.0025
Giardia lamblia Beta tubulin 0.0476 0.0777 1
Brugia malayi ABC transporter family protein 0.0027 0.0005 0.0021
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0086 0.0106 0.0875
Entamoeba histolytica ATP-binding cassette protein, putative 0.0027 0.0005 0.0033
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0046 0.0046
Onchocerca volvulus 0.0028 0.0007 0.0053
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0014 0.0073
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0066 0.0072 0.09
Echinococcus granulosus ATP binding cassette sub family G 0.005 0.0045 0.0045
Schistosoma mansoni phosphatidylserine receptor 0.0052 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0383
Brugia malayi Steroid receptor seven-up type 2 0.0062 0.0064 0.0511
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0041 0.0476
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0027 0.0005 0.0015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0064 0.0064
Onchocerca volvulus 0.0112 0.0151 0.1272
Echinococcus granulosus alpha tubulin 0.0351 0.0561 0.0561
Echinococcus multilocularis lipoxygenase domain containing protein 0.0122 0.0167 0.0167
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0036 0.0036
Echinococcus multilocularis peroxisome assembly protein 26 0.0351 0.0561 0.0561
Loa Loa (eye worm) hypothetical protein 0.0063 0.0067 0.04
Brugia malayi Melibiase family protein 0.0078 0.0092 0.0742
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0008 0.0048
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0052 0.0048 0.0567
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0064 0.0511
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0159 0.0159
Echinococcus granulosus multidrug resistance protein 1 0.0086 0.0106 0.0106
Loa Loa (eye worm) isocitrate dehydrogenase 0.0048 0.0041 0.0238
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0015 0.0095
Echinococcus multilocularis tar DNA binding protein 0.0318 0.0504 0.0504
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0159 0.0159
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0223 0.0342 0.0342
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0048 0.0041 0.0476
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0052 0.0048 0.0048
Echinococcus granulosus transcription factor btf3 0.0034 0.0017 0.0017
Brugia malayi Latrophilin receptor protein 2 0.018 0.0267 0.2192
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0086 0.0106 0.0875
Plasmodium vivax glutathione reductase, putative 0.0102 0.0134 0.1728
Onchocerca volvulus 0.0336 0.0535 0.4531
Onchocerca volvulus 0.0028 0.0007 0.0053
Loa Loa (eye worm) fibroinase 0.0028 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0051 0.0655
Leishmania major cathepsin L-like protease 0.0028 0.0007 0.0033
Brugia malayi hypothetical protein 0.0122 0.0167 0.1365
Brugia malayi hypothetical protein 0.0548 0.09 0.7441
Toxoplasma gondii PHD-finger domain-containing protein 0.0063 0.0067 0.0813
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0036
Echinococcus granulosus tubulin alpha 1C chain 0.0351 0.0561 0.0561
Schistosoma mansoni tubulin subunit alpha 0.0351 0.0561 0.0561
Giardia lamblia Gamma tubulin 0.0254 0.0395 0.507
Trichomonas vaginalis tubulin epsilon chain, putative 0.0351 0.0561 0.4743
Echinococcus multilocularis Smad4 0.005 0.0044 0.0044
Echinococcus granulosus Tubulin alpha 1 chain 0.0351 0.0561 0.0561
Brugia malayi Cell division protein ftsZ 0.011 0.0148 0.1206
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0027 0.0005 0.0015
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0036 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0064 0.0511
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0014 0.0097
Trichomonas vaginalis tubulin alpha chain, putative 0.0144 0.0206 0.1723
Plasmodium vivax vivapain-1 0.012 0.0164 0.2114
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0038 0.0432
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0064 0.0064
Trypanosoma cruzi ABC transporter, putative 0.005 0.0045 0.0527
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0117 0.0159 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4278 0.7309 0.7309
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0086 0.0106 0.0106
Echinococcus granulosus tubulin alpha chain 0.0351 0.0561 0.0561
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0059 0.006 0.0719
Trichomonas vaginalis tubulin, putative 0.0144 0.0206 0.1723
Echinococcus multilocularis tubulin alpha chain 0.0351 0.0561 0.0561
Leishmania major beta tubulin 0.0476 0.0777 1
Schistosoma mansoni netrin receptor unc5 0.0029 0.0008 0.0008
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0086 0.0106 0.0875
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0324 0.0515 0.1368
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0022 0.016
Echinococcus multilocularis tubulin alpha 1C chain 0.0351 0.0561 0.0561
Echinococcus multilocularis 0.0027 0.0005 0.0005
Plasmodium vivax tubulin gamma chain, putative 0.0254 0.0395 0.5086
Trichomonas vaginalis tubulin epsilon chain, putative 0.011 0.0148 0.1235
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0007 0.0052
Brugia malayi Cathepsin L-like precursor 0.0028 0.0007 0.0033
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0086 0.0106 0.0641
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0017 0.0168
Loa Loa (eye worm) hypothetical protein 0.0052 0.0048 0.0281
Echinococcus multilocularis TGF beta signal transducer SmadC 0.005 0.0044 0.0044
Trypanosoma brucei importin beta-1 subunit, putative 0.009 0.0113 0.1412
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0259 0.0404 0.3917
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0052 0.0048 0.0114
Echinococcus granulosus smad 0.005 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0214 0.0326 0.2012
Loa Loa (eye worm) hypothetical protein 0.0083 0.0101 0.0614
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0008 0.0048
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.006 0.0473
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.005 0.0045 0.0106
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0565 0.4774
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.005 0.0045 0.0527
Giardia lamblia NADH oxidase lateral transfer candidate 0.0035 0.0019 0.0217
Loa Loa (eye worm) latrophilin receptor protein 2 0.018 0.0267 0.1644
Loa Loa (eye worm) hypothetical protein 0.0237 0.0366 0.2263
Schistosoma mansoni tumor necrosis factor receptor related 0.0044 0.0034 0.0034
Schistosoma mansoni smdr1 0.0027 0.0005 0.0005
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0062 0.0064 0.0064
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0035 0.0019 0.0198
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0053 0.0312
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0036
Plasmodium falciparum thioredoxin reductase 0.0102 0.0134 0.1728
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0052 0.0048 0.0567
Echinococcus granulosus tubulin alpha chain 0.0351 0.0561 0.0561
Echinococcus multilocularis mothers against decapentaplegic 5 0.005 0.0044 0.0044
Brugia malayi hypothetical protein 0.0054 0.0051 0.0401
Brugia malayi AMP-binding enzyme family protein 0.007 0.0078 0.0625
Brugia malayi MH1 domain containing protein 0.0027 0.0006 0.0025
Brugia malayi nuclear receptor RXR 0.0029 0.0008 0.0048
Echinococcus multilocularis thyroid hormone receptor alpha 0.0062 0.0064 0.0064
Schistosoma mansoni tubulin subunit beta 0.0476 0.0777 0.0777
Echinococcus granulosus Smad4 0.005 0.0044 0.0044
Brugia malayi Tubulin beta chain 0.0144 0.0206 0.1683
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0086 0.0106 0.0875
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.0565 0.7262
Brugia malayi isocitrate dehydrogenase 0.0048 0.0041 0.0317
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0052 0.0048 0.0567
Schistosoma mansoni cathepsin F (C01 family) 0.0028 0.0007 0.0007
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0004 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0019 0.0198
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0263 0.2208
Trichomonas vaginalis tubulin, putative 0.011 0.0148 0.1235
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0038 0.0432
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0035 0.0019 0.0249
Leishmania major cathepsin L-like protease 0.0074 0.0086 0.1065
Loa Loa (eye worm) hypothetical protein 0.0078 0.0092 0.0557
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0279 0.2347
Loa Loa (eye worm) hypothetical protein 0.009 0.0113 0.0688
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0017 0.0168
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0476 0.0777 0.0777
Brugia malayi RNA recognition motif domain containing protein 0.0318 0.0504 0.4161
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0155 0.0224 0.285
Leishmania major alpha tubulin 0.0351 0.0561 0.721
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.018 0.0267 0.2192
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0727 0.1207 0.1207
Echinococcus granulosus multidrug resistance protein 1 0.0086 0.0106 0.0106
Trypanosoma cruzi ISWI complex protein 0.0046 0.0038 0.0439
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0062 0.0064 0.0064
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0207 0.0314 0.2646
Loa Loa (eye worm) hypothetical protein 0.0388 0.0625 0.3872
Loa Loa (eye worm) jmjC domain-containing protein 0.0204 0.0309 0.1909
Plasmodium falciparum ABC transporter B family member 5, putative 0.0027 0.0005 0.0067
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0086 0.0106 0.0875
Trypanosoma brucei epsilon tubulin 0.0254 0.0395 0.506
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0086 0.0106 0.0106
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.0084 0.069
Leishmania major alpha tubulin 0.0351 0.0561 0.721
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0013 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0062 0.0064 0.0511
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0017 0.009
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0233 0.036 0.095
Loa Loa (eye worm) hypothetical protein 0.0033 0.0014 0.0073
Brugia malayi Doublecortin family protein 0.0122 0.0167 0.1365
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0565 0.4774
Loa Loa (eye worm) hypothetical protein 0.007 0.0078 0.0469
Onchocerca volvulus 0.0058 0.0059 0.0494
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0422 0.3561
Plasmodium vivax ABC transporter B family member 3, putative 0.0027 0.0005 0.0067
Echinococcus multilocularis peptidase Clp (S14 family) 0.0212 0.0323 0.0323
Trypanosoma brucei ISWI complex protein 0.0046 0.0038 0.0439
Schistosoma mansoni multidrug resistance protein 0.0027 0.0005 0.0005
Leishmania major beta tubulin 0.0476 0.0777 1
Echinococcus granulosus tubulin epsilon chain 0.0254 0.0395 0.0395
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0324 0.0515 0.6615
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0567 0.0933 0.7718
Onchocerca volvulus Alhambra homolog 0.0063 0.0067 0.0563
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0041 0.0476
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0961 0.161 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0233 0.036 0.3477
Loa Loa (eye worm) tubulin beta-2A chain 0.0476 0.0777 0.4818
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0078 0.0195
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0114 0.0114
Entamoeba histolytica acyl-coA synthetase, putative 0.007 0.0078 0.0973
Echinococcus multilocularis ATP binding cassette sub family B 0.0027 0.0005 0.0005
Entamoeba histolytica cysteine protease, putative 0.0028 0.0007 0.0052
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0004 0.0008
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.062 0.1024 0.2733
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0028 0.0007 0.0007
Echinococcus multilocularis tubulin delta chain 0.011 0.0148 0.0148
Leishmania major beta tubulin 0.0476 0.0777 1
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0052 0.0048 0.0572
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0008 0.0068
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.005 0.0045 0.0106
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0007 0.0034
Toxoplasma gondii HEAT repeat-containing protein 0.009 0.0113 0.1412
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.006 0.006
Brugia malayi TAR-binding protein 0.0318 0.0504 0.4161
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.0194 0.0194
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0184 0.0274 0.0274
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0046 0.0367
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0126 0.0126
Schistosoma mansoni multidrug resistance protein 0.0027 0.0005 0.0005
Toxoplasma gondii alpha tubulin TUBA1 0.0351 0.0561 0.721
Echinococcus granulosus jumonji domain containing 1A 0.0052 0.0048 0.0048
Schistosoma mansoni tubulin subunit beta 0.0476 0.0777 0.0777
Loa Loa (eye worm) alpha-tubulin isotype 2 0.024 0.0372 0.2297
Onchocerca volvulus Cathepsin L homolog 0.0028 0.0007 0.0053
Mycobacterium tuberculosis Cell division protein FtsZ 0.011 0.0148 0.0383
Trichomonas vaginalis tubulin alpha chain, putative 0.0254 0.0395 0.3333
Loa Loa (eye worm) hypothetical protein 0.0027 0.0005 0.0016
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0144 0.0206 0.1723
Trypanosoma cruzi zeta tubulin, putative 0.011 0.0148 0.1863
Brugia malayi intermediate filament protein 0.0085 0.0104 0.084
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0004 0.0008
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0228 0.035 0.2161
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0086 0.0106 0.0106
Schistosoma mansoni tubulin subunit epsilon 0.0254 0.0395 0.0395
Schistosoma mansoni cellular tumor antigen P53 0.0058 0.0059 0.0059
Echinococcus granulosus ATP binding cassette sub family B 0.0027 0.0005 0.0005
Echinococcus multilocularis beta tubulin 0.0476 0.0777 0.0777
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.0078 0.0714
Schistosoma mansoni tar DNA-binding protein 0.0318 0.0504 0.0504
Schistosoma mansoni hypothetical protein 0.0062 0.0066 0.0066
Echinococcus multilocularis TNFR CD27 30 40 95 cysteine rich region 0.0044 0.0034 0.0034
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0027 0.0005 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0142 0.0203 0.0203
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0092 0.0092
Plasmodium vivax SET domain protein, putative 0.0091 0.0114 0.1472
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.005 0.0045 0.0264
Giardia lamblia Beta tubulin 0.0476 0.0777 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0046 0.054
Echinococcus granulosus Tubulin beta 2C chain 0.0476 0.0777 0.0777
Schistosoma mansoni tubulin subunit beta 0.0476 0.0777 0.0777
Loa Loa (eye worm) hypothetical protein 0.0183 0.0273 0.1681
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0078 0.0956
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0422 0.3561
Echinococcus multilocularis Tubulin beta 2C chain 0.0476 0.0777 0.0777
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0029 0.0008 0.0008
Leishmania major alpha tubulin 0.0351 0.0561 0.721
Leishmania major pentamidine resistance protein 1 0.0027 0.0005 0.0015
Trypanosoma cruzi epsilon tubulin, putative 0.0254 0.0395 0.506
Brugia malayi hypothetical protein 0.0033 0.0014 0.0097
Loa Loa (eye worm) hypothetical protein 0.0085 0.0104 0.063
Trypanosoma cruzi tubulin delta chain 0.011 0.0148 0.1863
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.0019 0.0198
Loa Loa (eye worm) TAR-binding protein 0.0318 0.0504 0.3122
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0076 0.0089 0.1642
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0422 0.3561
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.035 0.035
Loa Loa (eye worm) doublecortin family protein 0.0122 0.0167 0.1024
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0059 0.0351
Schistosoma mansoni ABC transporter 0.0043 0.0032 0.0032
Leishmania major beta tubulin 0.0476 0.0777 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0195 0.0294 0.0294
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0041 0.0041
Trypanosoma brucei beta tubulin 0.0476 0.0777 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0066 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0045 0.0036 0.0207
Treponema pallidum cell division protein FtsZ 0.011 0.0148 0.2359
Loa Loa (eye worm) tubulin gamma chain 0.0254 0.0395 0.2443
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0324 0.0515 0.5007
Loa Loa (eye worm) PHD-finger family protein 0.0062 0.0066 0.0392
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0062 0.0064 0.0064
Onchocerca volvulus 0.0711 0.118 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0051 0.0607
Brugia malayi Cathepsin L-like precursor 0.0028 0.0007 0.0033
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0029 0.0029
Echinococcus granulosus cathepsin l cysteine peptidase 0.0028 0.0007 0.0007
Loa Loa (eye worm) bromodomain containing protein 0.0053 0.005 0.0296
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0019 0.0198
Loa Loa (eye worm) hypothetical protein 0.0351 0.0561 0.3476
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0022 0.0226
Brugia malayi multidrug resistance protein 3 0.0086 0.0106 0.0854
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0022 0.0226
Schistosoma mansoni hypothetical protein 0.004 0.0027 0.0027
Plasmodium falciparum importin beta, putative 0.009 0.0113 0.1456
Onchocerca volvulus 0.0104 0.0137 0.1155
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0026 0.0003 0.0005
Leishmania major hypothetical protein, conserved 0.0052 0.0048 0.0567
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0014 0.0014
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0035 0.0019 0.0249
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0046 0.054
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0022 0.0226
Entamoeba histolytica hypothetical protein 0.0101 0.0132 0.1666
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0084 0.0103 0.0103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0086 0.1065
Echinococcus granulosus ATP binding cassette sub family G 0.005 0.0045 0.0045
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0062 0.0064 0.0064
Echinococcus multilocularis Tubulin alpha 1 chain 0.0351 0.0561 0.0561
Echinococcus granulosus neuropeptide s receptor 0.1982 0.3363 0.3363
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0043 0.0101
Schistosoma mansoni hypothetical protein 0.018 0.0267 0.0267
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0064 0.0064
Schistosoma mansoni tubulin subunit alpha 0.011 0.0148 0.0148
Echinococcus multilocularis lamin 0.0085 0.0104 0.0104
Plasmodium falciparum tubulin gamma chain 0.0254 0.0395 0.5086
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0004 0.0004
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.0565 0.7262
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.004 0.0027 0.0027
Plasmodium vivax ABC transporter B family member 4, putative 0.0027 0.0005 0.0067
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0324 0.0515 0.6632
Entamoeba histolytica ABC transporter, putative 0.005 0.0045 0.0544
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0022 0.0244
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0212 0.0323 0.0854
Trichomonas vaginalis tubulin alpha chain, putative 0.0144 0.0206 0.1723
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0048 0.0041 0.0041
Trypanosoma brucei RNA helicase, putative 0.0207 0.0314 0.4008
Trichomonas vaginalis chromobox protein, putative 0.0079 0.0095 0.0782
Echinococcus granulosus methyl CpG binding domain protein 2 0.0052 0.0047 0.0047
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0045 0.0036 0.0411
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.0051 0.0607
Loa Loa (eye worm) MH2 domain-containing protein 0.0727 0.1208 0.7503
Toxoplasma gondii cathepsin CPL 0.0028 0.0007 0.0033
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0325 0.0518 0.0518
Brugia malayi cytoplasmic intermediate filament protein 0.0045 0.0036 0.028
Loa Loa (eye worm) Smad1 0.005 0.0044 0.0255
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0327 0.052 0.6679
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0086 0.1065
Brugia malayi Tubulin alpha chain 0.0351 0.0561 0.4633
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0351 0.0561 0.4743
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0086 0.0106 0.0875
Loa Loa (eye worm) hypothetical protein 0.0567 0.0933 0.5791
Brugia malayi Death domain containing protein 0.0029 0.0008 0.0043
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0086 0.0106 0.0875
Echinococcus multilocularis beta tubulin 0.0476 0.0777 0.0777
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0019 0.0198
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0008 0.0008
Brugia malayi ABC transporter family protein 0.0027 0.0005 0.0021
Schistosoma mansoni multidrug resistance protein 0.0027 0.0005 0.0005
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0089 0.1099
Echinococcus granulosus PHD finger protein rhinoceros 0.0063 0.0067 0.0067
Echinococcus granulosus tubulin gamma 1 chain 0.0254 0.0395 0.0395
Echinococcus granulosus multidrug resistance associated protein 1 0.0027 0.0005 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0052 0.0048 0.0282
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0004 0.0019
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0004 0.0008
Trichomonas vaginalis tubulin, putative 0.0144 0.0206 0.1723
Trichomonas vaginalis tubulin gamma chain, putative 0.0476 0.0777 0.6574
Echinococcus granulosus thioredoxin glutathione reductase 0.0102 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0035 0.0018 0.0098
Echinococcus multilocularis multidrug resistance protein 1 0.006 0.0062 0.0062
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.024 0.0372 0.3134
Plasmodium falciparum multidrug resistance protein 1 0.0086 0.0106 0.1359
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0565 0.4774
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0004 0.0008
Schistosoma mansoni inositol monophosphatase 0.0037 0.0022 0.0022
Plasmodium vivax multidomain scavenger receptor, putative 0.0122 0.0167 0.2152
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0029 0.0008 0.0008
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0045 0.0036 0.0429
Loa Loa (eye worm) hypothetical protein 0.0336 0.0535 0.3313
Brugia malayi MH2 domain containing protein 0.005 0.0044 0.034
Mycobacterium ulcerans fatty-acid-CoA ligase 0.007 0.0078 0.0195
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0086 0.1065
Echinococcus granulosus netrin receptor unc 5 0.0029 0.0008 0.0008
Brugia malayi beta-NAC-like protein 0.0034 0.0017 0.0119
Plasmodium vivax ABC transporter B family member 6, putative 0.0027 0.0005 0.0067
Echinococcus multilocularis phd:f box containing protein 0.0052 0.0048 0.0048
Brugia malayi Tubulin gamma chain 0.0254 0.0395 0.3255
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0062 0.0064 0.0383
Echinococcus multilocularis hypothetical protein 0.0351 0.0561 0.0561
Toxoplasma gondii hypothetical protein 0.0053 0.0049 0.0583
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0263 0.2208
Entamoeba histolytica Ran family GTPase 0.0066 0.0072 0.09
Loa Loa (eye worm) hypothetical protein 0.0052 0.0048 0.0281
Echinococcus multilocularis Tubulin beta 2C chain 0.0476 0.0777 0.0777
Trichomonas vaginalis abcb9, putative 0.0086 0.0106 0.0875
Entamoeba histolytica tubulin alpha chain, putative 0.0351 0.0561 0.7215
Leishmania major alpha tubulin 0.0351 0.0561 0.721
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.0206 0.1723
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0043 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0064 0.0511
Schistosoma mansoni multidrug resistance protein 0.0086 0.0106 0.0106
Loa Loa (eye worm) jmjC domain-containing protein 0.0052 0.0048 0.0282
Trypanosoma brucei alpha tubulin 0.0351 0.0561 0.721
Loa Loa (eye worm) PHD-finger family protein 0.0063 0.0067 0.04
Echinococcus multilocularis isocitrate dehydrogenase 0.0048 0.0041 0.0041
Echinococcus multilocularis multidrug resistance protein 1 0.0086 0.0106 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0013 0.0085
Trichomonas vaginalis tubulin beta chain, putative 0.0351 0.0561 0.4743
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0029 0.0029
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0076 0.0089 0.1099
Trypanosoma cruzi trypanothione reductase, putative 0.0035 0.0019 0.0198
Echinococcus granulosus cpg binding protein 0.0068 0.0075 0.0075
Loa Loa (eye worm) RNA binding protein 0.0318 0.0504 0.3122
Giardia lamblia Multidrug resistance-associated protein 1 0.0027 0.0005 0.0033
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0008 0.0008
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.007 0.0078 0.0195
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0041 0.0041
Schistosoma mansoni jumonji domain containing protein 0.0283 0.0445 0.0445
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0112 0.015 0.24
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0015 0.0026
Schistosoma mansoni transcription factor btf3 0.0034 0.0017 0.0017
Onchocerca volvulus 0.0029 0.0008 0.0068
Leishmania major alpha tubulin 0.0351 0.0561 0.721
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0086 0.1065
Onchocerca volvulus 0.0028 0.0007 0.0053
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.0019 0.0198
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0159 0.0159
Brugia malayi MH1 domain containing protein 0.0027 0.0006 0.0025
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0327 0.052 0.6679
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0183 0.0273 0.2308
Echinococcus multilocularis thymidine phosphorylase 0.2197 0.3733 0.3733
Plasmodium vivax tubulin alpha chain, putative 0.0351 0.0561 0.7224
Mycobacterium ulcerans thymidine phosphorylase 0.2197 0.3733 1
Leishmania major beta tubulin 0.0476 0.0777 1
Brugia malayi jmjC domain containing protein 0.0325 0.0518 0.427
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0263 0.2208
Onchocerca volvulus 0.0085 0.0104 0.0877
Giardia lamblia PHD finger protein 15 0.0063 0.0067 0.083
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0086 0.0106 0.1739
Schistosoma mansoni smdr2 0.0086 0.0106 0.0106
Leishmania major ABC-thiol transporter 0.0027 0.0005 0.0015
Brugia malayi ABC transporter transmembrane region family protein 0.0027 0.0005 0.0021
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0086 0.0106 0.1314
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Echinococcus granulosus lipoxygenase domain containing protein 0.0122 0.0167 0.0167
Plasmodium vivax multidrug resistance protein 2, putative 0.0027 0.0005 0.0067
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.018 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0052 0.0048 0.0281
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0076 0.0089 0.1403
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0022 0.016
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0383
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.018 0.0267 0.0267
Echinococcus granulosus tubulin subunit beta 0.0476 0.0777 0.0777
Echinococcus multilocularis tubulin gamma 1 chain 0.0254 0.0395 0.0395
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0066 0.0072 0.0434
Schistosoma mansoni tar DNA-binding protein 0.0318 0.0504 0.0504
Plasmodium falciparum ABC transporter G family member 2 0.005 0.0045 0.0576
Brugia malayi Uncoordinated protein 44 0.0029 0.0008 0.0043
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0004 0.0008
Brugia malayi hypothetical protein 0.0029 0.0008 0.0048
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0046 0.054
Trichomonas vaginalis tubulin epsilon chain, putative 0.0476 0.0777 0.6574
Toxoplasma gondii alpha-tubulin I, putative 0.0351 0.0561 0.721
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.0043
Onchocerca volvulus Bile acid receptor homolog 0.0062 0.0064 0.0541
Schistosoma mansoni hypothetical protein 0.004 0.0027 0.0027
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0062 0.0064 0.0064
Plasmodium falciparum ABC transporter B family member 7, putative 0.0027 0.0005 0.0067
Trypanosoma brucei beta tubulin 0.0254 0.0395 0.506
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0324 0.0515 1
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.0255 0.0669
Plasmodium vivax JmjC domain containing protein 0.0052 0.0048 0.0616
Echinococcus granulosus ATP binding cassette sub family G 0.005 0.0045 0.0045
Brugia malayi glutathione reductase 0.0102 0.0134 0.1092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0007 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0035 0.0274
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.004 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0058 0.0059 0.0349
Brugia malayi Tubulin alpha-2 chain 0.0351 0.0561 0.4633
Leishmania major alpha tubulin 0.0351 0.0561 0.721
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.0565 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0062 0.0064 0.0511
Giardia lamblia ABC transporter, putative 0.0027 0.0005 0.0033
Brugia malayi Heterochromatin protein 1 0.0079 0.0095 0.0764
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0017 0.0168
Plasmodium vivax acyl-CoA synthetase, putative 0.0052 0.0048 0.0614
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0036
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0063 0.0067 0.0067
Loa Loa (eye worm) tubulin beta-4 chain 0.0476 0.0777 0.4818
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0078 0.0092 0.076
Echinococcus multilocularis survival motor neuron protein 1 0.0548 0.09 0.09
Echinococcus multilocularis Polycystic kidney disease protein 0.0122 0.0167 0.0167
Loa Loa (eye worm) cysteine protease 0.0028 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0383
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0123 0.1001
Echinococcus multilocularis cathepsin L cysteine protease 0.0028 0.0007 0.0007
Leishmania major cysteine peptidase A (CPA) 0.0028 0.0007 0.0033
Trypanosoma brucei beta tubulin 0.0476 0.0777 1
Onchocerca volvulus 0.0144 0.0206 0.1739
Trypanosoma cruzi epsilon tubulin, putative 0.0254 0.0395 0.506
Loa Loa (eye worm) hypothetical protein 0.0044 0.0035 0.0201
Loa Loa (eye worm) hypothetical protein 0.0054 0.0051 0.0301
Echinococcus multilocularis jumonji domain containing protein 0.0088 0.0109 0.0109
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0565 0.4774
Loa Loa (eye worm) hypothetical protein 0.014 0.0199 0.122
Plasmodium vivax unspecified product 0.0107 0.0142 0.183
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0017 0.0218
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0086 0.0106 0.0269
Brugia malayi MAP kinase sur-1 0.0051 0.0046 0.0358
Trichomonas vaginalis tubulin beta-1 chain, putative 0.011 0.0148 0.1235
Schistosoma mansoni chromobox protein 0.0079 0.0095 0.0095
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.006 0.006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0142 0.0203 0.0203
Trichomonas vaginalis tubulin beta chain, putative 0.0351 0.0561 0.4743
Schistosoma mansoni hypothetical protein 0.0833 0.139 0.139
Leishmania major beta tubulin 0.0476 0.0777 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0086 0.0106 0.0106
Trypanosoma cruzi ISWI complex protein 0.0046 0.0038 0.0439
Plasmodium falciparum multidrug resistance protein 2 0.0027 0.0005 0.0067
Leishmania major cathepsin L-like protease 0.0074 0.0086 0.1065
Loa Loa (eye worm) tubulin alpha chain 0.0351 0.0561 0.3476
Trichomonas vaginalis tubulin beta chain, putative 0.0476 0.0777 0.6574
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0061 0.0064 0.0064
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0155 0.0224 0.285
Entamoeba histolytica tubulin family protein 0.0476 0.0777 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0038 0.0432
Giardia lamblia Beta tubulin 0.0476 0.0777 1
Onchocerca volvulus 0.0059 0.0059 0.0497
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.011 0.0148 0.2801
Toxoplasma gondii ABC transporter family protein 0.0027 0.0005 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0148 0.1235
Schistosoma mansoni coup transcription factor 0.0062 0.0064 0.0064
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0078 0.0195
Toxoplasma gondii thioredoxin reductase 0.0102 0.0134 0.1685
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0086 0.1065
Loa Loa (eye worm) hypothetical protein 0.0142 0.0203 0.1247
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.027 0.0422 0.3481
Trypanosoma brucei alpha tubulin, putative 0.0144 0.0206 0.2607
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0354 0.0567 0.7288
Plasmodium vivax tubulin epsilon chain, putative 0.0254 0.0395 0.5086
Loa Loa (eye worm) hypothetical protein 0.0324 0.0515 0.319
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0041 0.0029 0.0065
Schistosoma mansoni lamin 0.0085 0.0104 0.0104
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0062 0.0064 0.0383
Trichomonas vaginalis tubulin, putative 0.0476 0.0777 0.6574
Plasmodium falciparum alpha tubulin 1 0.0351 0.0561 0.7224
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0263 0.2208
Schistosoma mansoni loxhd1 0.0122 0.0167 0.0167
Leishmania major alpha tubulin 0.0351 0.0561 0.721
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0112 0.0151 0.1226
Echinococcus multilocularis cpg binding protein 0.0068 0.0075 0.0075
Schistosoma mansoni smad 0.005 0.0044 0.0044
Echinococcus granulosus ATP binding cassette sub family B 0.0027 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0226
Onchocerca volvulus 0.0035 0.0018 0.0153
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0033
Trichomonas vaginalis ABC transporter, putative 0.0086 0.0106 0.0875
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.027 0.0422 0.261

Activities

Activity type Activity value Assay description Source Reference
Potency (binding) = 7.9433 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Vif-A3F Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 12.5594 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 21.3313 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 35.4813 uM PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1484, AID504370, AID504374, AID504375] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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