Detailed information for compound 145092

Basic information

Technical information
  • TDR Targets ID: 145092
  • Name: 2-phenylquinoline
  • MW: 205.255 | Formula: C15H11N
  • H donors: 0 H acceptors: 1 LogP: 3.85 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc(cc1)c1ccc2c(n1)cccc2
  • InChi: 1S/C15H11N/c1-2-6-12(7-3-1)15-11-10-13-8-4-5-9-14(13)16-15/h1-11H
  • InChiKey: FSEXLNMNADBYJU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 612-96-4
  • AIDS-167239
  • AIDS167239
  • .alpha.-Phenylquinoline
  • NSC118137
  • Quinoline, 2-phenyl-
  • ST5306928
  • Bionet2_001089
  • 299650_ALDRICH
  • ZINC01395181
  • EINECS 210-326-7

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens parathyroid hormone 1 receptor Starlite/ChEMBL No references
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K04588 secretin receptor, putative Get druggable targets OG5_139196 All targets in OG5_139196
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0043 0.0127 0.0138
Trypanosoma brucei multidrug resistance protein E 0.003 0.0059 0.0281
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0393 0.1897 0.2059
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0047 0.0147 0.016
Echinococcus granulosus lipoxygenase domain containing protein 0.0054 0.0184 0.0184
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0043 0.0127 0.0127
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0026 0.0039 0.0174
Echinococcus multilocularis protein jagged 2 0.0334 0.1596 0.1732
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0393 0.1897 0.2059
Brugia malayi ABC transporter transmembrane region family protein 0.0019 0.0002 0.0003
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0019 0.0006 0.0024
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0172 0.0778 0.0778
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0177 0.0192
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0011 0.0028
Schistosoma mansoni notch 0.0334 0.1597 0.1734
Echinococcus granulosus dro:myosuppressin receptor 0.002 0.0009 0.0009
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0047 0.0147 0.016
Loa Loa (eye worm) hypothetical protein 0.0098 0.0402 0.0437
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0009 0.0009
Onchocerca volvulus 0.0098 0.0402 0.0435
Echinococcus granulosus multidrug resistance associated protein 7 0.003 0.0059 0.0059
Echinococcus multilocularis BC026374 protein (S09 family) 0.0031 0.0064 0.0069
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0033 0.0077 0.0083
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0055 0.0184 0.02
Loa Loa (eye worm) hypothetical protein 0.0026 0.0041 0.0044
Schistosoma mansoni phd/f-box containing protein 0.0024 0.0031 0.0034
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0049 0.0156 0.0815
Giardia lamblia ABC transporter, putative 0.003 0.0059 0.0221
Loa Loa (eye worm) hypothetical protein 0.0027 0.0044 0.0048
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0032 0.0071 0.0343
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0031 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0024 0.0031 0.0135
Loa Loa (eye worm) notch protein 0.0334 0.1596 0.1732
Echinococcus granulosus multidrug resistance protein 1 0.0055 0.0184 0.0184
Schistosoma mansoni amine GPCR 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Plasmodium vivax flavodoxin domain containing protein 0.0023 0.0024 0.011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0038 0.0041
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0176 0.0928
Onchocerca volvulus 0.1841 0.9215 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0176 0.09
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0194 0.0194
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0148 0.0148
Onchocerca volvulus 0.002 0.0009 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0024 0.0031 0.0135
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0334 0.1596 0.1732
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0023 0.0026 0.0028
Onchocerca volvulus 0.0466 0.2266 0.2458
Echinococcus multilocularis notch 0.0334 0.1596 0.1732
Schistosoma mansoni cytochrome P450 0.0024 0.0031 0.0034
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0024 0.0031 0.0135
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0087 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0154
Schistosoma mansoni jumonji domain containing protein 0.0131 0.0569 0.0618
Echinococcus multilocularis thyroid hormone receptor alpha 0.0219 0.1016 0.1103
Schistosoma mansoni nuclear receptor 0.0046 0.0141 0.0154
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0109 0.0544
Onchocerca volvulus 0.0031 0.0064 0.0068
Echinococcus multilocularis sex peptide receptor 0.002 0.0009 0.0009
Brugia malayi Death domain containing protein 0.0023 0.0026 0.0028
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0073 0.0408
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0024 0.0031 0.0135
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0031 0.0165
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0028
Leishmania major 4-coumarate:coa ligase-like protein 0.002 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0044 0.0048
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0085 0.045
Schistosoma mansoni pyruvate kinase 0.0033 0.0073 0.0079
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.002 0.0009 0.0009
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0073 0.0385
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0052 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0022 0.0085
Onchocerca volvulus 0.002 0.0009 0.0008
Mycobacterium tuberculosis Carboxylesterase LipT 0.0031 0.0064 0.0307
Schistosoma mansoni phosphatidylserine receptor 0.0024 0.0031 0.0034
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0098 0.0402 0.0437
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.003 0.0059 0.0281
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0172 0.067
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.0456 0.2378
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0085 0.0421
Schistosoma mansoni pol-related 0.0393 0.1897 0.2059
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0172 0.0778 0.4096
Echinococcus multilocularis pyruvate kinase 0.0033 0.0073 0.0079
Loa Loa (eye worm) hypothetical protein 0.0137 0.0599 0.065
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0176 0.09
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0058 0.02 0.0217
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.002 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0163 0.0734 0.287
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0035 0.0087 0.1279
Echinococcus granulosus cytochrome P450 2K1 0.0024 0.0031 0.0031
Echinococcus multilocularis Polycystic kidney disease protein 0.0054 0.0184 0.0199
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0061 0.0216 0.0235
Echinococcus granulosus peptide allatostatin:somatostatin 0.002 0.0009 0.0009
Echinococcus granulosus neurogenic locus notch protein 4 0.0334 0.1596 0.1596
Toxoplasma gondii TIM10 family protein, putative 0.0058 0.02 0.1048
Giardia lamblia Aldose reductase 0.0393 0.1897 0.7411
Brugia malayi larval opioid receptor 0.002 0.0009 0.0009
Trichomonas vaginalis adenylate cyclase, putative 0.0035 0.0087 0.0341
Echinococcus multilocularis peregrin 0.0028 0.0052 0.0057
Entamoeba histolytica ATP-binding cassette protein, putative 0.003 0.0059 0.0231
Brugia malayi EGF-like domain containing protein 0.0334 0.1596 0.1732
Schistosoma mansoni slit 0.0334 0.1596 0.1732
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) Notch2 0.0334 0.1596 0.1732
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0205 0.0223
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0613 0.3234
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0032 0.0071 0.0343
Schistosoma mansoni follistatin 0.0018 0.0001 0.0001
Echinococcus granulosus neural cadherin 0.0334 0.1596 0.1596
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Loa Loa (eye worm) FAD binding domain-containing protein 0.0026 0.0039 0.0042
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0062 0.0343
Trichomonas vaginalis aldo-keto reductase, putative 0.0172 0.0778 0.3039
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0141 0.0622 0.0675
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0205 0.0223
Echinococcus multilocularis g protein coupled receptor 0.002 0.0009 0.0009
Brugia malayi nuclear receptor RXR 0.0046 0.0141 0.0154
Plasmodium vivax SET domain protein, putative 0.0059 0.0205 0.1211
Echinococcus granulosus hypothetical protein 0.0393 0.1897 0.1897
Loa Loa (eye worm) TK/EGFR protein kinase 0.0144 0.0635 0.069
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0024 0.0031 0.0135
Schistosoma mansoni hypothetical protein 0.002 0.0009 0.0009
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0393 0.1897 0.2059
Onchocerca volvulus Glucosylceramidase homolog 0.0163 0.0734 0.0796
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0044 0.0234
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0024 0.0031 0.0034
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0024 0.0031 0.0135
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0058 0.02 0.0217
Echinococcus multilocularis RUN 0.0054 0.0184 0.0199
Onchocerca volvulus Peroxidase homolog 0.1841 0.9215 1
Brugia malayi hypothetical protein 0.002 0.0009 0.0009
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0098 0.0402 0.0437
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0137 0.0599 0.065
Schistosoma mansoni multidrug resistance protein 0.0055 0.0184 0.02
Echinococcus multilocularis lysine specific demethylase 6a 0.0024 0.0031 0.0034
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0052 0.0282
Echinococcus multilocularis neuropeptide receptor 0.002 0.0009 0.0009
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0024 0.0031 0.0159
Echinococcus multilocularis fmrfamide receptor 0.002 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0024 0.0031 0.0135
Onchocerca volvulus 0.0334 0.1596 0.1731
Schistosoma mansoni glucose transport protein 0.0047 0.0147 0.016
Loa Loa (eye worm) hypothetical protein 0.0031 0.0064 0.0069
Echinococcus multilocularis biogenic amine (5HT) receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0098 0.0402 0.0437
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0032 0.0072 0.035
Onchocerca volvulus 0.0101 0.0418 0.0452
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0019 0.0006 0.0023
Brugia malayi bHLH-PAS transcription factor 0.0101 0.0418 0.0453
Echinococcus multilocularis serine protein kinase ATM 0.0032 0.0072 0.0078
Trypanosoma brucei multidrug resistance-associated protein, putative 0.003 0.0059 0.0281
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0035 0.0087 0.046
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0251 0.1176 0.1276
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0009 0.0009
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0148 0.0865
Echinococcus granulosus multidrug resistance protein 1 0.0036 0.009 0.009
Echinococcus multilocularis lamin 0.0053 0.0177 0.0192
Echinococcus granulosus serine protein kinase ATM 0.0032 0.0072 0.0072
Echinococcus granulosus tumor protein p63 0.0408 0.1971 0.1971
Mycobacterium ulcerans hypothetical protein 0.002 0.0008 0.0011
Onchocerca volvulus 0.002 0.0009 0.0008
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0326 0.1555 0.1688
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0022 0.0085
Echinococcus multilocularis voltage gated potassium channel subunit 0.0172 0.0778 0.0844
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0019 0.0002 0.001
Schistosoma mansoni single-minded 0.0136 0.0596 0.0647
Leishmania major prostaglandin f synthase, putative 0.0393 0.1897 1
Trypanosoma brucei trypanothione reductase 0.0047 0.0148 0.0753
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0024 0.0031 0.0135
Trypanosoma brucei aldo-keto reductase, putative 0.0393 0.1897 1
Brugia malayi Uncoordinated protein 44 0.0023 0.0026 0.0028
Trichomonas vaginalis abcb9, putative 0.0055 0.0184 0.0721
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0022 0.0022 0.0109
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0073 0.0079
Echinococcus granulosus delta-like protein 1 0.0334 0.1596 0.1596
Toxoplasma gondii exonuclease III APE 0.0034 0.0079 0.041
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0098 0.0402 0.0437
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0022 0.0022 0.0024
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0076 0.0082
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0207 0.0207
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.016 0.0626
Onchocerca volvulus 0.0055 0.0184 0.0199
Plasmodium vivax glyoxalase I, putative 0.0345 0.1653 1
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0312 0.122
Entamoeba histolytica acyl-CoA synthetase, putative 0.002 0.0008 0.0031
Entamoeba histolytica hypothetical protein 0.0123 0.0529 0.2068
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0164 0.0863
Echinococcus multilocularis 0.0024 0.0031 0.0034
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0024 0.0031 0.0159
Trichomonas vaginalis aldo-keto reductase, putative 0.0393 0.1897 0.7413
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0024 0.0031 0.0135
Brugia malayi Animal haem peroxidase family protein 0.1841 0.9215 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0144 0.0156
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0055 0.0184 0.0184
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0393 0.1897 0.2059
Brugia malayi hypothetical protein 0.002 0.0009 0.0009
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0613 0.3213
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0018 0.0001 0.0001
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.002 0.0009 0.0009
Plasmodium vivax multidrug resistance protein 1, putative 0.0055 0.0184 0.1084
Brugia malayi Thioredoxin reductase 0.0047 0.0148 0.0161
Plasmodium falciparum hexose transporter 0.0047 0.0147 0.0858
Brugia malayi M-phase phosphoprotein, mpp8 0.0109 0.046 0.0499
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0009 0.0009
Echinococcus multilocularis neuroligin 0.0031 0.0064 0.0069
Mycobacterium leprae conserved hypothetical protein 0.008 0.0312 0.162
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0031 0.0064 0.0069
Trichomonas vaginalis ABC transporter, putative 0.0055 0.0184 0.0721
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.002 0.0009 0.0009
Brugia malayi Animal haem peroxidase family protein 0.1841 0.9215 1
Trichomonas vaginalis ap endonuclease, putative 0.0034 0.0079 0.0309
Trichomonas vaginalis spcc417.12 protein, putative 0.0031 0.0064 0.0249
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0098 0.0402 0.0437
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0046 0.0141 0.0154
Brugia malayi AMP-binding enzyme family protein 0.002 0.0008 0.0009
Plasmodium vivax aldehyde reductase, putative 0.0172 0.0778 0.4686
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0052 0.0057
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0061 0.0216 0.0216
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0024
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0038 0.0038
Echinococcus multilocularis alpha 1A adrenergic receptor 0.002 0.0009 0.0009
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0009 0.0009
Plasmodium falciparum JmjC domain-containing protein, putative 0.0024 0.0031 0.0155
Brugia malayi Carboxylesterase family protein 0.0031 0.0064 0.0069
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0207 0.0225
Schistosoma mansoni steroid hormone receptor ad4bp 0.0098 0.0402 0.0437
Leishmania major 4-coumarate:coa ligase-like protein 0.002 0.0008 0.0011
Echinococcus multilocularis G protein coupled receptor 139 0.002 0.0009 0.0009
Onchocerca volvulus 0.0027 0.0044 0.0047
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0073 0.0079
Trichomonas vaginalis aldo-keto reductase, putative 0.0393 0.1897 0.7413
Echinococcus granulosus g protein coupled receptor 0.002 0.0009 0.0009
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0019 0.0006 0.0031
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0076 0.0082
Mycobacterium leprae Conserved hypothetical protein 0.0221 0.1028 0.5403
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0524 0.2559 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0393 0.1897 0.1897
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.016 0.0626
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0055 0.0184 0.02
Echinococcus granulosus sex peptide receptor 0.002 0.0009 0.0009
Echinococcus granulosus lipoxygenase domain containing protein 0.0054 0.0184 0.0184
Brugia malayi Animal haem peroxidase family protein 0.1841 0.9215 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.016 0.0626
Echinococcus granulosus protein jagged 1 0.0334 0.1596 0.1596
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0115 0.0451
Onchocerca volvulus 0.0393 0.1897 0.2058
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0184 0.0721
Brugia malayi 4-hydroxyphenylpyruvate dioxygenase family protein 0.008 0.0312 0.0339
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0035 0.0087 0.046
Loa Loa (eye worm) hypothetical protein 0.0043 0.0127 0.0138
Schistosoma mansoni hypothetical protein 0.0123 0.0529 0.0574
Brugia malayi AKH receptor 0.002 0.0009 0.0009
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0087 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0172 0.067
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0334 0.1596 0.1732
Loa Loa (eye worm) oxidoreductase 0.0393 0.1897 0.2059
Brugia malayi MH2 domain containing protein 0.0099 0.041 0.0445
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0116 0.0452
Schistosoma mansoni hypothetical protein 0.0334 0.1596 0.1732
Toxoplasma gondii ABC transporter, putative 0.0019 0.0006 0.0024
Schistosoma mansoni chromobox protein 0.0081 0.0317 0.0345
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0085 0.0093
Loa Loa (eye worm) hypothetical protein 0.0027 0.0044 0.0048
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0022 0.0085
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0009 0.0009
Mycobacterium tuberculosis Conserved protein 0.008 0.0312 0.162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0176 0.09
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0024 0.0031 0.0135
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0071 0.0373
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0184 0.0721
Brugia malayi EGF-like domain containing protein 0.0334 0.1596 0.1732
Brugia malayi Carboxylesterase family protein 0.0031 0.0064 0.0069
Loa Loa (eye worm) hypothetical protein 0.0027 0.0044 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0312 0.122
Loa Loa (eye worm) hypothetical protein 0.0457 0.2216 0.2405
Echinococcus multilocularis epidermal growth factor receptor 0.0144 0.0635 0.069
Entamoeba histolytica aldose reductase, putative 0.0393 0.1897 0.7413
Mycobacterium leprae Possible regulatory protein 0.0035 0.0087 0.043
Loa Loa (eye worm) animal heme peroxidase 0.1841 0.9215 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0176 0.09
Echinococcus multilocularis multidrug resistance associated protein 7 0.003 0.0059 0.0064
Entamoeba histolytica hypothetical protein 0.0022 0.0022 0.0085
Brugia malayi exodeoxyribonuclease III family protein 0.0034 0.0079 0.0086
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0035 0.0087 0.0095
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0026 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0087 0.0341
Loa Loa (eye worm) sugar transporter 0.0047 0.0147 0.016
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0154
Echinococcus granulosus JmjC domain containing protein 4 0.0024 0.0031 0.0031
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0076 0.0082
Toxoplasma gondii ABC1 family protein 0.0035 0.0085 0.0444
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0098 0.0402 0.0437
Schistosoma mansoni cellular tumor antigen P53 0.006 0.021 0.0228
Trichomonas vaginalis glucosylceramidase, putative 0.0163 0.0734 0.287
Echinococcus granulosus neuropeptide receptor 0.002 0.0009 0.0009
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0256 0.1203 0.6331
Schistosoma mansoni notch 0.0334 0.1596 0.1732
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0176 0.0928
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0101 0.0394
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0034 0.0079 0.0387
Schistosoma mansoni hypothetical protein 0.0043 0.0127 0.0138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0172 0.067
Brugia malayi CHD4 protein 0.0022 0.0022 0.0024
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0061 0.0216 0.1141
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0009 0.0009
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0085 0.0334
Loa Loa (eye worm) hypothetical protein 0.0053 0.0177 0.0192
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0141 0.0141
Echinococcus granulosus aldo keto reductase 0.0393 0.1897 0.1897
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0098 0.0402 0.0437
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0118 0.0622
Onchocerca volvulus 0.006 0.021 0.0227
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0098 0.0402 0.0435
Brugia malayi G protein-coupled receptor 0.002 0.0009 0.0009
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0098 0.0402 0.0437
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0216 0.0846
Leishmania major pentamidine resistance protein 1 0.003 0.0059 0.0281
Echinococcus granulosus 7TM GPCR rhodopsin 0.002 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0022 0.0022 0.0024
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0009 0.0009
Onchocerca volvulus 0.0109 0.046 0.0498
Entamoeba histolytica hypothetical protein 0.0123 0.0529 0.2068
Schistosoma mansoni tyrosine kinase 0.0077 0.0299 0.0325
Onchocerca volvulus 0.0031 0.0064 0.0068
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0031 0.0034
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0184 0.0721
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0393 0.1897 0.1897
Echinococcus granulosus thyroid hormone receptor alpha 0.0046 0.0141 0.0141
Schistosoma mansoni notch 0.0334 0.1596 0.1732
Toxoplasma gondii target of rapamycin (TOR), putative 0.005 0.016 0.0839
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0393 0.1897 0.7413
Echinococcus granulosus Polycystic kidney disease protein 0.0054 0.0184 0.0184
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0524 0.2559 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0106 0.0115
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Toxoplasma gondii facilitative glucose transporter GT1 0.0047 0.0147 0.077
Brugia malayi conserved hypotetical protein 0.0046 0.0141 0.0154
Schistosoma mansoni multidrug resistance protein 0.0055 0.0184 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0087 0.0341
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0778 0.3039
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0141 0.0154
Echinococcus granulosus neuroligin 0.0031 0.0064 0.0064
Brugia malayi FAD binding domain containing protein 0.0026 0.0039 0.0042
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0034 0.0079 0.0444
Loa Loa (eye worm) heterochromatin protein 1 0.0081 0.0317 0.0345
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0109 0.0544
Echinococcus granulosus lysine specific demethylase 5A 0.0091 0.0369 0.0369
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0073 0.0285
Loa Loa (eye worm) hypothetical protein 0.0031 0.0064 0.0069
Echinococcus granulosus neurogenic locus protein delta 0.0334 0.1596 0.1596
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.002 0.0009 0.0009
Echinococcus granulosus acetylcholinesterase 0.0182 0.0828 0.0828
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0023 0.0027 0.0029
Echinococcus multilocularis allatostatin A receptor 0.002 0.0009 0.0009
Schistosoma mansoni BC026374 protein (S09 family) 0.0031 0.0064 0.0069
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Loa Loa (eye worm) hypothetical protein 0.0031 0.0064 0.0069
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0393 0.1897 1
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0073 0.0355
Schistosoma mansoni hypothetical protein 0.002 0.0009 0.0009
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0148 0.0161
Echinococcus multilocularis aldehyde reductase 0.0221 0.1028 0.1115
Entamoeba histolytica ABC transporter, putative 0.003 0.0059 0.0231
Echinococcus granulosus hypothetical protein 0.002 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.016 0.0626
Brugia malayi hypothetical protein 0.0027 0.0044 0.0048
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0022 0.0022 0.0024
Entamoeba histolytica P-glycoprotein-2 0.0055 0.0184 0.0721
Loa Loa (eye worm) hypothetical protein 0.0054 0.0181 0.0196
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.002 0.0009 0.0009
Onchocerca volvulus Slit protein homolog 0.0334 0.1596 0.1731
Loa Loa (eye worm) hypothetical protein 0.0039 0.0106 0.0115
Echinococcus granulosus agrin 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0154
Loa Loa (eye worm) hypothetical protein 0.0031 0.0064 0.0069
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0046 0.0141 0.0154
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0026 0.0039 0.0174
Echinococcus granulosus fatty acid binding protein FABP2 0.0033 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Echinococcus granulosus jumonji domain containing protein 0.004 0.0109 0.0109
Echinococcus multilocularis multidrug resistance protein 1 0.0036 0.009 0.0098
Trichomonas vaginalis glucosylceramidase, putative 0.0163 0.0734 0.287
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Loa Loa (eye worm) hypothetical protein 0.0318 0.1518 0.1647
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0082 0.0324 0.0324
Echinococcus multilocularis neurogenic locus protein delta 0.0334 0.1596 0.1732
Leishmania major trypanothione reductase 0.0047 0.0148 0.0753
Loa Loa (eye worm) hypothetical protein 0.0035 0.0087 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0109 0.0544
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Echinococcus granulosus somatostatin receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0044 0.0048
Brugia malayi follicle stimulating hormone receptor 0.0251 0.1176 0.1276
Schistosoma mansoni aldo-keto reductase 0.0393 0.1897 0.2059
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0026 0.0028
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0098 0.0402 0.0437
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0085 0.0421
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.016 0.0626
Trypanosoma brucei unspecified product 0.0033 0.0076 0.0373
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0216 0.0846
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0024 0.0031 0.0135
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0018 0.0001 0.0001
Schistosoma mansoni multidrug resistance protein 0.003 0.0059 0.0064
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0032 0.0071 0.0077
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0047 0.0147 0.0147
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.002 0.0008 0.0011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0524 0.2559 1
Schistosoma mansoni hypothetical protein 0.0121 0.0522 0.0567
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0059 0.0205 0.1077
Brugia malayi nuclear receptor NHR-67 0.0046 0.0141 0.0154
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0073 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0002 0.001
Plasmodium vivax heterochromatin protein 1, putative 0.0022 0.0022 0.0097
Onchocerca volvulus 0.0046 0.0141 0.0152
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0085
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.002 0.0012 0.0061
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0024 0.0031 0.0135
Onchocerca volvulus 0.0109 0.046 0.0498
Mycobacterium leprae Possible oxidoreductase 0.0172 0.0778 0.4082
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.0613 0.3213
Brugia malayi hypothetical protein 0.0031 0.0064 0.0069
Mycobacterium ulcerans biphenyl-2,3-diol 1,2-dioxygenase 0.008 0.0312 0.162
Onchocerca volvulus Heterochromatin protein 1 homolog 0.005 0.0162 0.0175
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0034 0.0079 0.0299
Loa Loa (eye worm) glutathione reductase 0.0047 0.0148 0.0161
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Onchocerca volvulus 0.0047 0.0144 0.0155
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0085 0.0421
Brugia malayi hypothetical protein 0.1841 0.9215 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0024
Echinococcus multilocularis lipoxygenase domain containing protein 0.0054 0.0184 0.0199
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0046 0.0141 0.0152
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0098 0.0402 0.0402
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0071 0.0277
Brugia malayi hypothetical protein 0.0046 0.0141 0.0154
Echinococcus granulosus para nitrobenzyl esterase 0.0031 0.0064 0.0064
Entamoeba histolytica aldose reductase, putative 0.0393 0.1897 0.7413
Brugia malayi Sugar transporter family protein 0.0047 0.0147 0.016
Echinococcus multilocularis tumor protein p63 0.0408 0.1971 0.2139
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0019 0.0002 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0163 0.0734 0.287
Plasmodium vivax hexose transporter 0.0047 0.0147 0.0858
Brugia malayi hypothetical protein 0.0052 0.0169 0.0184
Schistosoma mansoni chromobox protein 0.0081 0.0317 0.0345
Onchocerca volvulus Protein ultraspiracle homolog 0.0098 0.0402 0.0435
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0009 0.0009
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.002 0.0009 0.0009
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0073 0.0079
Onchocerca volvulus 0.0334 0.1596 0.1731
Echinococcus granulosus lamin 0.0053 0.0177 0.0177
Onchocerca volvulus 0.0047 0.0144 0.0155
Giardia lamblia Multidrug resistance-associated protein 1 0.003 0.0059 0.0221
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0109 0.0544
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0109 0.0424
Loa Loa (eye worm) hypothetical protein 0.0026 0.0039 0.0042
Echinococcus multilocularis musashi 0.0053 0.0177 0.0192
Echinococcus multilocularis aldo keto reductase 0.0393 0.1897 0.2059
Loa Loa (eye worm) hypothetical protein 0.0098 0.0402 0.0437
Brugia malayi hypothetical protein 0.0109 0.0461 0.05
Trypanosoma cruzi aldo-keto reductase 0.0393 0.1897 1
Loa Loa (eye worm) hypothetical protein 0.0098 0.0402 0.0437
Schistosoma mansoni notch 0.0334 0.1596 0.1732
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0009 0.0009
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0073 0.0355
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0022 0.0022 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0022 0.0085
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0049 0.0156 0.091
Schistosoma mansoni gliotactin 0.0031 0.0064 0.0069
Brugia malayi EGF-like domain containing protein 0.0334 0.1596 0.1732
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0024 0.0031 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0116 0.0452
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0034 0.0079 0.0416
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0062 0.0298
Brugia malayi jmjC domain containing protein 0.0024 0.0031 0.0034
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0052 0.0172 0.0877
Brugia malayi ABC transporter family protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0098 0.0402 0.0437
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0023 0.0024 0.0093
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0109 0.0544
Leishmania major ABC-thiol transporter 0.003 0.0059 0.0281
Brugia malayi Carboxylesterase family protein 0.0182 0.0828 0.0899
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0034 0.0079 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.002 0.0009 0.0009
Entamoeba histolytica P-glycoprotein-2, putative 0.0019 0.0002 0.001
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Onchocerca volvulus 0.0027 0.0044 0.0047
Onchocerca volvulus Netrin receptor homolog 0.0023 0.0026 0.0027
Echinococcus granulosus ATP binding cassette sub family B 0.0019 0.0002 0.0002
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0026 0.0039 0.0204
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Echinococcus multilocularis chromobox protein 1 0.0081 0.0317 0.0345
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.002 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1167 0.4562
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.002 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0022 0.0085
Echinococcus multilocularis ATP binding cassette sub family B 0.0019 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0109 0.0544
Echinococcus granulosus orexin receptor type 2 0.002 0.0009 0.0009
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0184 0.0721
Onchocerca volvulus 0.0081 0.0319 0.0345
Loa Loa (eye worm) hypothetical protein 0.003 0.0059 0.0064
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0098 0.0402 0.0437
Loa Loa (eye worm) cytochrome P450 family protein 0.0081 0.0318 0.0345
Echinococcus multilocularis neurogenic locus protein delta 0.0334 0.1596 0.1732
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.0456 0.2378
Echinococcus multilocularis ATP binding cassette sub family B 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0176 0.09
Brugia malayi AMP-binding enzyme family protein 0.002 0.0008 0.0009
Brugia malayi putative neuropeptide receptor 0.002 0.0009 0.0009
Leishmania major 4-coumarate:coa ligase-like protein 0.002 0.0008 0.0011
Schistosoma mansoni aryl hydrocarbon receptor 0.0136 0.0596 0.0647
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.002 0.0009 0.0009
Mycobacterium ulcerans oxidoreductase 0.0393 0.1897 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0059 0.0207 0.1066
Echinococcus granulosus aryl hydrocarbon receptor 0.0035 0.0087 0.0087
Echinococcus granulosus microtubule associated protein 2 0.0666 0.3272 0.3272
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0047 0.0144 0.0729
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.0456 0.2378
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0085 0.0334
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0093
Schistosoma mansoni hypothetical protein 0.002 0.0009 0.0009
Echinococcus multilocularis dro:myosuppressin receptor 0.002 0.0009 0.0009
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Schistosoma mansoni neuropeptide receptor 0.002 0.0009 0.0009
Brugia malayi hypothetical protein 0.0054 0.0184 0.0199
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0073 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0098 0.0402 0.0437
Schistosoma mansoni hypothetical protein 0.0334 0.1596 0.1732
Onchocerca volvulus 0.0393 0.1897 0.2058
Onchocerca volvulus Peroxidasin homolog 0.1841 0.9215 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0249 0.1167 0.1267
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0393 0.1897 0.2059
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0326 0.1555 0.1555
Trypanosoma brucei p-glycoprotein 0.003 0.0059 0.0281
Plasmodium vivax multidomain scavenger receptor, putative 0.0054 0.0184 0.108
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0317 0.1241
Onchocerca volvulus 0.0047 0.0144 0.0155
Loa Loa (eye worm) hypoxia-induced factor 1 0.0421 0.2038 0.2211
Entamoeba histolytica alcohol dehydrogenase, putative 0.0172 0.0778 0.3039
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0024 0.0031 0.0135
Brugia malayi Latrophilin receptor protein 2 0.0043 0.0127 0.0138
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0032 0.0071 0.0077
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0019 0.0006 0.0024
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0035 0.0087 0.0341
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0024 0.0031 0.0135
Loa Loa (eye worm) agrin synaptic family protein 0.0018 0.0001 0.0001
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0019 0.0006 0.0024
Echinococcus granulosus neuropeptide receptor A26 0.0464 0.2251 0.2251
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0024 0.0031 0.0135
Echinococcus multilocularis fatty acid binding protein FABP2 0.0033 0.0077 0.0083
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0009 0.0009
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0043 0.0127 0.0138
Schistosoma mansoni ap endonuclease 0.0034 0.0079 0.0086
Onchocerca volvulus 0.0393 0.1897 0.2058
Loa Loa (eye worm) animal heme peroxidase 0.1841 0.9215 1
Echinococcus multilocularis orexin receptor type 2 0.002 0.0009 0.0009
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0085 0.0421
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.002 0.0009 0.0009
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0026 0.0039 0.0174
Brugia malayi G-protein coupled receptor 0.002 0.0009 0.0009
Brugia malayi hypothetical protein 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0009 0.0009
Brugia malayi Muscle positioning protein 4 0.0334 0.1596 0.1732
Onchocerca volvulus 0.002 0.0009 0.0008
Brugia malayi EGF-like domain containing protein 0.0334 0.1596 0.1732
Loa Loa (eye worm) nuclear hormone receptor 0.0046 0.0141 0.0154
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0061 0.0216 0.1113
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0032 0.0072 0.0078
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0076 0.0373
Echinococcus granulosus chromobox protein 2 0.0022 0.0022 0.0022
Echinococcus multilocularis multidrug resistance protein 1 0.0055 0.0184 0.02
Brugia malayi Nuclear hormone receptor E75 0.0046 0.0141 0.0154
Leishmania major pyruvate kinase 0.0033 0.0073 0.0355
Trichomonas vaginalis glucosylceramidase, putative 0.0163 0.0734 0.287
Brugia malayi Nuclear hormone receptor E75 0.0046 0.0141 0.0154
Schistosoma mansoni organic anion transporter 0.0027 0.0044 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0022 0.0085
Entamoeba histolytica P-glycoprotein-2, putative 0.0055 0.0184 0.0721
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0085 0.0483
Echinococcus granulosus histone lysine methyltransferase setb 0.0059 0.0205 0.0205
Plasmodium vivax glutathione reductase, putative 0.0047 0.0148 0.0865
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0059 0.0207 0.0225
Echinococcus multilocularis chromobox protein 1 0.0081 0.0317 0.0345
Echinococcus granulosus thyrotropin releasing hormone receptor 0.002 0.0009 0.0009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0085
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0034 0.0079 0.0086
Trichomonas vaginalis aldo/keto reductase, putative 0.0393 0.1897 0.7413
Echinococcus multilocularis para nitrobenzyl esterase 0.0031 0.0064 0.0069
Echinococcus granulosus ecdysone induced protein 78C 0.0098 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0024
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0207 0.0225
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0022 0.0024
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0034
Trichomonas vaginalis aldo-keto reductase, putative 0.0393 0.1897 0.7413
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0082 0.0324 0.0351
Brugia malayi ABC transporter family protein 0.0019 0.0006 0.0006
Trichomonas vaginalis guanylate cyclase, putative 0.0035 0.0087 0.0341
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0085 0.045
Echinococcus multilocularis pyruvate kinase 0.0033 0.0073 0.0079
Echinococcus granulosus carboxylesterase 5A 0.0182 0.0828 0.0828
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0207 0.1066
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0034 0.0079 0.0086
Trichomonas vaginalis Heterochromatin protein, putative 0.0022 0.0022 0.0085
Brugia malayi ABC transporter transmembrane region family protein 0.0019 0.0006 0.0006
Schistosoma mansoni intermediate filament proteins 0.0053 0.0177 0.0192
Loa Loa (eye worm) cytochrome P450 0.0024 0.0031 0.0034
Schistosoma mansoni tyrosine kinase 0.0046 0.0141 0.0153
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0098 0.0402 0.0437
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0073 0.0079
Echinococcus multilocularis somatostatin receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0052 0.0172 0.0186
Schistosoma mansoni organic anion transporter 0.0027 0.0044 0.0048
Brugia malayi AMP-binding enzyme family protein 0.002 0.0008 0.0009
Schistosoma mansoni retinoic acid receptor RXR 0.0193 0.0883 0.0958
Brugia malayi hypothetical protein 0.003 0.0062 0.0068
Schistosoma mansoni tyrosine kinase 0.0076 0.0295 0.032
Echinococcus multilocularis ATP binding cassette sub family B 0.0019 0.0006 0.0006
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0524 0.2559 1
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0046 0.0141 0.0153
Leishmania major protein kinase, putative 0.0035 0.0087 0.043
Echinococcus granulosus protein jagged 1 0.0334 0.1596 0.1596
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0035 0.0087 0.0087
Echinococcus granulosus protein jagged 2 0.0334 0.1596 0.1596
Trypanosoma cruzi cruzipain precursor, putative 0.0053 0.0176 0.0928
Leishmania major pyruvate kinase 0.0033 0.0073 0.0355
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0035 0.0087 0.0341
Trypanosoma cruzi p450 reductase, putative 0.0026 0.0039 0.0204
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Brugia malayi hypothetical protein 0.002 0.0009 0.0009
Echinococcus multilocularis g protein coupled receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0046 0.0141 0.0154
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0334 0.1596 0.1731
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0071 0.0277
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0044 0.0048
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0144 0.0729
Schistosoma mansoni adenoreceptor 0.002 0.0009 0.0009
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0052 0.0169 0.0184
Trichomonas vaginalis ABC transporter, putative 0.0055 0.0184 0.0721
Brugia malayi steroid hormone receptor 0.0098 0.0402 0.0437
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0115 0.0451
Mycobacterium ulcerans hypothetical protein 0.008 0.0312 0.162
Toxoplasma gondii FATC domain-containing protein 0.0032 0.0072 0.0373
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0044 0.0048
Brugia malayi nuclear receptor RXR 0.0052 0.0169 0.0184
Trichomonas vaginalis chromobox protein, putative 0.0053 0.0177 0.0692
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0022 0.0085
Brugia malayi prostaglandin transporter 0.0027 0.0044 0.0048
Echinococcus multilocularis 0.0019 0.0006 0.0006
Echinococcus multilocularis protein jagged 1 0.0334 0.1596 0.1732
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.002 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0147 0.0575
Onchocerca volvulus 0.002 0.0008 0.0007
Mycobacterium ulcerans hypothetical protein 0.0172 0.0778 0.4082
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0205 0.0223
Brugia malayi hypothetical protein 0.0052 0.0169 0.0184
Schistosoma mansoni lipoxygenase 0.0228 0.106 0.115
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0046 0.0141 0.0141
Echinococcus granulosus follistatin 0.0018 0.0001 0.0001
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0026 0.0039 0.02
Loa Loa (eye worm) steroid hormone receptor 0.0098 0.0402 0.0437
Schistosoma mansoni ankyrin 23/unc44 0.0023 0.0026 0.0028
Trichomonas vaginalis glucosylceramidase, putative 0.0163 0.0734 0.287
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0109 0.0544
Schistosoma mansoni tyrosine kinase 0.0077 0.0299 0.0325
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0098 0.0402 0.0437
Schistosoma mansoni jumonji/arid domain-containing protein 0.0091 0.0369 0.0401
Echinococcus multilocularis protein jagged 1 0.0334 0.1596 0.1732
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0176 0.09
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0024 0.0031 0.0135
Echinococcus granulosus phd:f box containing protein 0.0024 0.0031 0.0031
Brugia malayi jmjC domain containing protein 0.015 0.0666 0.0723
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0109 0.0544
Echinococcus granulosus epidermal growth factor receptor 0.0144 0.0635 0.0635
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0087 0.0341
Toxoplasma gondii MAPEG family protein 0.0093 0.038 0.1998
Mycobacterium ulcerans carboxylesterase, LipT 0.0031 0.0064 0.0307
Trichomonas vaginalis aldo-keto reductase, putative 0.0393 0.1897 0.7413
Echinococcus multilocularis acetylcholinesterase 0.0182 0.0828 0.0899
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0347 0.0376
Echinococcus granulosus Nuclear hormone receptor HR96 0.0046 0.0141 0.0141
Leishmania major cathepsin L-like protease 0.0053 0.0176 0.09
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.003 0.0059 0.0311
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0082 0.0324 0.0324
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0184 0.0721
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0031 0.0064 0.0069
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0177 0.0192
Onchocerca volvulus 0.0035 0.0087 0.0093
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0144 0.0156
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0052 0.0169 0.0184
Echinococcus multilocularis JmjC domain containing protein 4 0.0024 0.0031 0.0034
Schistosoma mansoni polycystin 1-related 0.0054 0.0184 0.0199
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0054 0.0184 0.0199
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0071 0.0077
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0009 0.0009
Mycobacterium tuberculosis Conserved hypothetical protein 0.008 0.0312 0.162
Brugia malayi small heat shock protein 0.0355 0.17 0.1845
Brugia malayi Blistered cuticle protein 3 0.1841 0.9215 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0184 0.0721
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0184 0.0721
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0032 0.0072 0.0281
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0024 0.0031 0.0165
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0779 0.3044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0176 0.09
Entamoeba histolytica aldose reductase, putative 0.0393 0.1897 0.7413
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0071 0.0077
Schistosoma mansoni gynecophoral canal protein 0.008 0.0312 0.0339
Echinococcus granulosus Ankyrin 0.0023 0.0027 0.0027
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0055 0.0184 0.0944
Echinococcus granulosus neurogenic locus notch protein 0.0334 0.1596 0.1596
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0085
Leishmania major aldo-keto reductase-like protein 0.0393 0.1897 1
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0022 0.0085
Brugia malayi neuropeptide F receptor 0.002 0.0009 0.0009
Schistosoma mansoni acetylcholinesterase 0.0031 0.0064 0.0069
Echinococcus multilocularis tachykinin peptides receptor 99D 0.002 0.0009 0.0009
Onchocerca volvulus Neuropeptide F receptor homolog 0.002 0.0009 0.0008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0207 0.1066
Echinococcus granulosus aldo keto reductase 0.0393 0.1897 0.1897
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0046 0.0141 0.0154
Trichomonas vaginalis aldo-keto reductase, putative 0.0393 0.1897 0.7413
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0154
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0184 0.0721
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1167 0.4562
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0334 0.1596 0.1732
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0109 0.046 0.0499
Echinococcus multilocularis chromobox protein 2 0.0022 0.0022 0.0024
Schistosoma mansoni fatty acid binding protein 0.0033 0.0077 0.0083
Schistosoma mansoni neuropeptide receptor 0.002 0.0009 0.0009
Echinococcus multilocularis neurogenic locus notch protein 0.0334 0.1596 0.1732
Entamoeba histolytica ATP-binding cassette protein, putative 0.003 0.0059 0.0231
Brugia malayi nuclear receptor NHR-88 0.0098 0.0402 0.0437
Echinococcus multilocularis pyruvate kinase 0.0026 0.0038 0.0042
Onchocerca volvulus 0.002 0.0009 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0022 0.0085
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.017 0.0184
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0055 0.0184 0.0184
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.015 0.0666 0.0723
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0049 0.0156 0.0169
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0144 0.0156
Echinococcus multilocularis acetylcholinesterase 0.0182 0.0828 0.0899
Loa Loa (eye worm) hypothetical protein 0.0055 0.0184 0.02
Trichomonas vaginalis aldo/keto reductase, putative 0.0393 0.1897 0.7413
Leishmania major cathepsin L-like protease 0.0053 0.0176 0.09
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0109 0.0118
Echinococcus multilocularis aryl hydrocarbon receptor 0.0035 0.0087 0.0095
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0009 0.0009
Brugia malayi nuclear hormone receptor 0.0098 0.0402 0.0437
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0055 0.0184 0.0721
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0052 0.0169 0.0184
Schistosoma mansoni neuroligin 3 (S09 family) 0.0031 0.0064 0.0069
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0008 0.0011
Loa Loa (eye worm) beta-lactamase 0.0035 0.0085 0.0093
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0031 0.0064 0.0069
Brugia malayi EGF-like domain containing protein 0.0334 0.1596 0.1732
Echinococcus multilocularis lipoxygenase domain containing protein 0.0054 0.0184 0.0199
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0148 0.0782
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0024 0.0031 0.0135
Onchocerca volvulus 0.0053 0.0177 0.019
Onchocerca volvulus 0.0031 0.0064 0.0068
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0347 0.0376
Trichomonas vaginalis glucosylceramidase, putative 0.0163 0.0734 0.287
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0055 0.0184 0.02
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0047 0.0147 0.0147
Onchocerca volvulus Peroxidase homolog 0.1841 0.9215 1
Schistosoma mansoni hypothetical protein 0.0049 0.0156 0.0169
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0032 0.0071 0.0343
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0046 0.0141 0.0152
Brugia malayi Carboxylesterase family protein 0.0031 0.0064 0.0069
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0009 0.0009
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.003 0.0059 0.0281
Trichomonas vaginalis aldo-keto reductase, putative 0.0393 0.1897 0.7413
Loa Loa (eye worm) melatonin receptor type 1A 0.002 0.0009 0.0009
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0022 0.0022 0.0022
Echinococcus multilocularis neuropeptide receptor A26 0.0464 0.2251 0.2443
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1167 0.4562
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0085 0.0421
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0127 0.0496
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0052 0.0057
Leishmania major cytochrome P450 reductase, putative 0.0023 0.0024 0.0096
Brugia malayi Animal haem peroxidase family protein 0.1841 0.9215 1
Giardia lamblia GTOR 0.0061 0.0216 0.0837
Echinococcus granulosus voltage gated potassium channel subunit 0.0172 0.0778 0.0778
Loa Loa (eye worm) oxidoreductase 0.0393 0.1897 0.2059
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0034 0.0079 0.0309
Leishmania major cytochrome p450-like protein 0.0024 0.0031 0.0135
Echinococcus granulosus insulin receptor 0.0046 0.0141 0.0141
Echinococcus multilocularis microtubule associated protein 2 0.0666 0.3272 0.3551
Leishmania major mitochondrial DNA polymerase beta 0.0295 0.1398 0.7362
Schistosoma mansoni multidrug resistance protein 0.003 0.0059 0.0064
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Onchocerca volvulus 0.0047 0.0144 0.0155
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0109 0.0573
Plasmodium vivax JmjC domain containing protein 0.0024 0.0031 0.0155
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0032 0.0071 0.0071
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0008 0.0011
Schistosoma mansoni hypothetical protein 0.0024 0.0031 0.0034
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0098 0.0402 0.0402
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0061 0.0216 0.1113
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0044 0.0048
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0184 0.0721
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0022 0.0097
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0172 0.0778 0.3039
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0009 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0009 0.0009
Echinococcus multilocularis General substrate transporter 0.003 0.0059 0.0064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0009 0.0009
Leishmania major DNA polymerase kappa, putative 0.002 0.0011 0.0028
Echinococcus granulosus 7tm_1 domain containing protein 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0393 0.1897 0.2059
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0035 0.0087 0.043
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0031 0.0064 0.0064
Schistosoma mansoni rab6-interacting 0.0054 0.0184 0.0199
Echinococcus granulosus lysine specific demethylase 6a 0.0024 0.0031 0.0031
Trichomonas vaginalis aldo-keto reductase, putative 0.0393 0.1897 0.7413
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0098 0.0402 0.0437
Mycobacterium tuberculosis Probable oxidoreductase 0.0393 0.1897 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.002 0.0009 0.0009
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0256 0.1203 0.6331
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0098 0.0402 0.0437
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0062 0.0328
Loa Loa (eye worm) hypothetical protein 0.0049 0.0156 0.0169
Echinococcus granulosus protein jagged 2 0.0334 0.1596 0.1596
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0085 0.0334
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0393 0.1897 0.2059
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0022 0.0022 0.0024
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.0693 0.3634
Onchocerca volvulus 0.0334 0.1596 0.1731
Mycobacterium leprae Probable lipase LipE 0.0035 0.0085 0.0421
Echinococcus multilocularis G-protein coupled receptor, putative 0.002 0.0009 0.0009
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.003 0.0059 0.0311
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.0517 0.2701
Brugia malayi Cadherin domain containing protein 0.0334 0.1596 0.1732
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0033 0.0077 0.0083
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0022 0.0085
Schistosoma mansoni amine GPCR 0.002 0.0009 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.006 0.0286
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0024
Onchocerca volvulus Dual oxidase homolog 0.1841 0.9215 1
Brugia malayi EGF-like domain containing protein 0.0334 0.1596 0.1732
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0345 0.1653 0.8715
Schistosoma mansoni hypothetical protein 0.0093 0.0381 0.0413
Echinococcus granulosus chromobox protein 1 0.0081 0.0317 0.0317
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0034 0.0079 0.0387
Echinococcus granulosus neuropeptide FF receptor 2 0.002 0.0009 0.0009
Echinococcus granulosus fatty acid binding protein FABP2 0.0033 0.0077 0.0077
Echinococcus multilocularis neural cadherin 0.0334 0.1596 0.1732
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0076 0.0399
Loa Loa (eye worm) doublecortin family protein 0.0054 0.0184 0.0199
Echinococcus granulosus acetylcholinesterase 0.0182 0.0828 0.0828
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0009 0.0009
Loa Loa (eye worm) ABC transporter 0.0019 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0116 0.0452
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0089 0.035
Loa Loa (eye worm) hypothetical protein 0.0098 0.0402 0.0437
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Echinococcus multilocularis serotonin receptor 0.002 0.0009 0.0009
Echinococcus granulosus allatostatin A receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0009
Loa Loa (eye worm) acetylcholinesterase 1 0.0182 0.0828 0.0899
Schistosoma mansoni biogenic amine receptor 0.002 0.0009 0.0009
Trichomonas vaginalis sulfite reductase, putative 0.0026 0.0039 0.0151
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0172 0.0778 0.4082
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0393 0.1897 0.1897
Brugia malayi cytochrome P450 0.0024 0.0031 0.0034
Giardia lamblia Nitric oxide synthase, inducible 0.0023 0.0024 0.0084
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.002 0.0008 0.0011
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0029 0.0123
Giardia lamblia Pyruvate kinase 0.0033 0.0073 0.0276
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0009 0.0009
Onchocerca volvulus 0.0031 0.0064 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.002 0.001 0.0041
Brugia malayi Dopamine receptor protein 1 0.002 0.0009 0.0009
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0059 0.0207 0.1066
Brugia malayi RE15519p 0.002 0.0009 0.0009
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0184 0.0721
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0393 0.1897 1
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0162 0.0634
Loa Loa (eye worm) hypothetical protein 0.0098 0.0402 0.0437
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0085 0.0093
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.1398 0.737
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0047 0.0147 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0049 0.019
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0022 0.0022 0.0109
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0779 0.3044
Loa Loa (eye worm) hypothetical protein 0.0182 0.0828 0.0899
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0026 0.0039 0.0174
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0031 0.0165
Echinococcus multilocularis neurogenic locus notch protein 4 0.0334 0.1596 0.1732
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0091 0.0369 0.0401
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0031 0.0064 0.0249
Onchocerca volvulus Neurogenic locus notch homolog 0.0334 0.1597 0.1732
Brugia malayi nuclear hormone receptor family member odr-7 0.0046 0.0141 0.0154
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0123 0.0529 0.0529
Brugia malayi beta-lactamase family protein 0.0035 0.0085 0.0093
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0035 0.0087 0.046
Giardia lamblia DINP protein human, muc B family 0.002 0.0011 0.0034
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0524 0.2559 1
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0087 0.0347 0.0376
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.002 0.0008 0.0011
Mycobacterium tuberculosis Conserved protein 0.0035 0.0085 0.0421
Loa Loa (eye worm) hypothetical protein 0.0098 0.0402 0.0437
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0009 0.0009
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0044 0.0047
Schistosoma mansoni peroxidasin 0.1841 0.9215 1
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0093 0.038 0.0412
Entamoeba histolytica hypothetical protein 0.0022 0.0022 0.0085
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0098 0.0402 0.0437
Trichomonas vaginalis ABC transporter, putative 0.0055 0.0184 0.0721
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0009 0.0009
Echinococcus granulosus death domain containing protein 0.0023 0.0026 0.0026
Brugia malayi Nuclear hormone receptor-like 1 0.0098 0.0402 0.0437
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0098 0.0402 0.0437
Brugia malayi beta-lactamase family protein 0.0035 0.0085 0.0093
Echinococcus multilocularis epidermal growth factor receptor 0.0077 0.0299 0.0325
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0184 0.0721
Leishmania major cytochrome p450-like protein 0.0024 0.0031 0.0135
Echinococcus granulosus netrin receptor unc 5 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0031 0.0064 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0098 0.0402 0.0437
Toxoplasma gondii hypothetical protein 0.0048 0.0149 0.0778
Schistosoma mansoni laminin gamma-3 chain 0.0334 0.1596 0.1732
Loa Loa (eye worm) hypothetical protein 0.003 0.0062 0.0068
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0076 0.037
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.002 0.0009 0.0009
Echinococcus multilocularis dna polymerase kappa 0.004 0.0109 0.0118
Loa Loa (eye worm) transcription factor SMAD2 0.0099 0.041 0.0445
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0055 0.0184 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0019 0.0006 0.0024
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0073 0.0078
Schistosoma mansoni notch 0.0334 0.1596 0.1732
Echinococcus granulosus g-protein coupled receptor 0.002 0.0009 0.0009
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0035 0.0087 0.0341
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0393 0.1897 0.1897
Leishmania major protein kinase, putative 0.0035 0.0087 0.043
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0249 0.1167 0.1267
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0036
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0024 0.0031 0.0135
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0044 0.0048
Brugia malayi intermediate filament protein 0.0053 0.0177 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0172 0.067
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0022 0.0097
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0182 0.0828 0.0899
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0141 0.0154
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0024 0.0031 0.0135
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0085 0.0421
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0031 0.0165
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0022 0.0022 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0111 0.0435
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0098 0.0402 0.0402
Schistosoma mansoni hypothetical protein 0.002 0.0009 0.0009
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0055 0.0184 0.0184
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0169 0.0184
Schistosoma mansoni potassium channel beta 0.0172 0.0778 0.0844
Echinococcus multilocularis g-protein coupled receptor 0.002 0.0009 0.0009
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0098 0.0402 0.0437
Loa Loa (eye worm) carboxylesterase 0.0031 0.0064 0.0069
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0393 0.1897 0.2059
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0393 0.1897 0.7413
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0098 0.0402 0.0437
Schistosoma mansoni lamin 0.0053 0.0177 0.0192
Schistosoma mansoni growth hormone secretagogue receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0052 0.0057
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0055 0.0184 0.0721
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0172 0.0778 0.0844
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0393 0.1897 0.2059
Brugia malayi Calcium binding EGF domain containing protein 0.0334 0.1596 0.1732
Trichomonas vaginalis aldo-keto reductase, putative 0.0393 0.1897 0.7413
Echinococcus multilocularis fibropellin Ia 0.0334 0.1596 0.1732
Leishmania major p450 reductase, putative 0.0026 0.0039 0.0174
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.0456 0.2378
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0003
Echinococcus granulosus serotonin receptor 0.002 0.0009 0.0009
Echinococcus multilocularis 0.0045 0.0133 0.0145
Schistosoma mansoni hypothetical protein 0.0334 0.1596 0.1732
Brugia malayi Cytochrome P450 family protein 0.0024 0.0031 0.0034
Schistosoma mansoni nuclear receptor nhr-48 0.0046 0.0141 0.0154
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.0517 0.2701
Loa Loa (eye worm) DR-78 0.0046 0.0141 0.0154
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0024 0.0031 0.0135
Echinococcus granulosus expressed protein 0.0058 0.02 0.02
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0073 0.0078
Leishmania major hypothetical protein, conserved 0.0035 0.0085 0.0421
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0077 0.0299 0.0299
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1167 0.4562
Brugia malayi hypothetical protein 0.0046 0.0141 0.0154
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0052 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0162 0.0634
Echinococcus granulosus geminin 0.0205 0.0943 0.0943
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0146 0.0569
Echinococcus multilocularis lamin dm0 0.0053 0.0177 0.0192
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0032 0.0072 0.0379
Brugia malayi Pre-SET motif family protein 0.0059 0.0205 0.0223
Mycobacterium tuberculosis Conserved protein 0.0035 0.0085 0.0421
Schistosoma mansoni biogenic amine receptor 0.002 0.0009 0.0009
Onchocerca volvulus 0.002 0.0009 0.0008
Leishmania major phosphatidylinositol 3-kinase, putative 0.0032 0.0071 0.0343
Trichomonas vaginalis aldo-keto reductase, putative 0.0393 0.1897 0.7413
Brugia malayi Protein kinase domain containing protein 0.0023 0.0026 0.0028
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0098 0.0402 0.0437
Brugia malayi hypothetical protein 0.0044 0.0132 0.0143
Leishmania major glyoxalase I,trypanothione-dependent glyoxalase I 0.0345 0.1653 0.8711
Schistosoma mansoni transcription factor LCR-F1 0.0123 0.0529 0.0574
Brugia malayi ABC transporter family protein 0.0055 0.0184 0.02
Echinococcus granulosus GPCR family 2 0.0043 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0052 0.0169 0.0184
Onchocerca volvulus Lactoylglutathione lyase homolog 0.0345 0.1653 0.1793
Toxoplasma gondii glyoxalase I, putative 0.0345 0.1653 0.8714
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0118 0.0622
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0073 0.0378
Loa Loa (eye worm) hypothetical protein 0.0064 0.0231 0.0251
Loa Loa (eye worm) oxidoreductase 0.0393 0.1897 0.2059
Onchocerca volvulus 0.0047 0.0144 0.0155
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0055 0.0184 0.02
Onchocerca volvulus 0.0031 0.0064 0.0068
Echinococcus granulosus multidrug resistance protein 1 0.0055 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Trypanosoma brucei prostaglandin f synthase 0.0393 0.1897 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0055 0.0184 0.02
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0393 0.1897 0.2059
Brugia malayi ORL1-like opioid receptor 0.002 0.0009 0.0009
Echinococcus multilocularis geminin 0.0205 0.0943 0.1023
Mycobacterium ulcerans hypothetical protein 0.0035 0.0085 0.0421
Loa Loa (eye worm) hypothetical protein 0.006 0.021 0.0228
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0345 0.1653 0.8715
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0172 0.0778 0.4096
Brugia malayi ABC transporter 0.0019 0.0002 0.0003
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0046 0.0141 0.0141
Echinococcus granulosus ATP binding cassette sub family B 0.0019 0.0006 0.0006
Echinococcus multilocularis multidrug resistance protein 1 0.0055 0.0184 0.02
Brugia malayi photoreceptor-specific nuclear receptor 0.0098 0.0402 0.0437
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.0517 0.2701
Echinococcus multilocularis lysine specific demethylase 5A 0.0091 0.0369 0.0401
Onchocerca volvulus 0.0046 0.0141 0.0152
Brugia malayi Cytochrome P450 family protein 0.0033 0.0076 0.0082
Brugia malayi ABC transporter family protein 0.0019 0.0006 0.0006
Brugia malayi Melatonin receptor type 1A 0.002 0.0009 0.0009
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0026 0.0039 0.0039
Brugia malayi jmjC domain containing protein 0.0024 0.0031 0.0034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Brugia malayi dehydrogenases, short chain protein 2 0.0047 0.0144 0.0156
Echinococcus multilocularis aldo keto reductase 0.0393 0.1897 0.2059
Schistosoma mansoni notch 0.0334 0.1596 0.1732
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0073 0.0385
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Schistosoma mansoni thyroid hormone receptor 0.0219 0.1016 0.1103
Loa Loa (eye worm) CHromoDomain protein family member 0.0022 0.0022 0.0024
Onchocerca volvulus Putative protein 0.008 0.0312 0.0337
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0044 0.0047
Plasmodium falciparum glyoxalase I 0.008 0.0312 0.186
Toxoplasma gondii aldo-keto reductase 0.0172 0.0778 0.4096
Loa Loa (eye worm) hypothetical protein 0.0033 0.0073 0.0079
Trichomonas vaginalis ABC transporter, putative 0.0055 0.0184 0.0721
Schistosoma mansoni neuropeptide receptor 0.002 0.0009 0.0009
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0022 0.0022 0.0024
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0184 0.0721
Brugia malayi Serotonin receptor 0.002 0.0009 0.0009
Brugia malayi hypothetical protein 0.0457 0.2216 0.2405
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0055 0.0184 0.0721
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0009 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0009 0.0009
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0026 0.0039 0.0204
Toxoplasma gondii EGF family domain-containing protein 0.0334 0.1596 0.8414
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.006 0.0286
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0052 0.0169 0.0169
Echinococcus granulosus Chromobox protein 3 0.0022 0.0022 0.0022
Onchocerca volvulus 0.0027 0.0044 0.0047
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0393 0.1897 0.2059
Loa Loa (eye worm) TYRA-2 protein 0.002 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0172 0.067
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0109 0.0424
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.002 0.0009 0.0009
Brugia malayi G protein-coupled receptor F59B2.13 0.002 0.0009 0.0009
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0061 0.0216 0.1113
Toxoplasma gondii aldose reductase, putative 0.0393 0.1897 1
Onchocerca volvulus 0.0172 0.0778 0.0843
Brugia malayi ABC transporter transmembrane region family protein 0.003 0.0059 0.0064
Trichomonas vaginalis aldo-keto reductase, putative 0.0393 0.1897 0.7413
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.002 0.0009 0.0009
Mycobacterium ulcerans hypothetical protein 0.0155 0.0693 0.3634
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0055 0.0184 0.0721
Brugia malayi sulfakinin receptor protein 0.002 0.0009 0.0009
Brugia malayi P-glycoprotein-like protein 0.0019 0.0006 0.0006
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0011 0.0028
Echinococcus granulosus single minded 2 0.0101 0.0418 0.0418
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0176 0.0928
Mycobacterium ulcerans hypothetical protein 0.008 0.0312 0.162
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0023 0.0026 0.0026
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0024 0.0031 0.0135
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0081 0.0319 0.0346
Entamoeba histolytica multidrug resistance protein, putative 0.003 0.0059 0.0231
Loa Loa (eye worm) hypothetical protein 0.005 0.0162 0.0176
Schistosoma mansoni loxhd1 0.0054 0.0184 0.0199
Loa Loa (eye worm) hypothetical protein 0.0027 0.0044 0.0048
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0034
Schistosoma mansoni multidrug resistance protein 0.0055 0.0184 0.02
Echinococcus granulosus General substrate transporter 0.003 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0154
Echinococcus multilocularis expressed protein 0.0018 0.0001 0.0001
Trichomonas vaginalis ap endonuclease, putative 0.0034 0.0079 0.0309
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0024 0.0031 0.0135
Trypanosoma cruzi multidrug resistance protein E, putative 0.003 0.0059 0.0311
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0085 0.0421
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0019 0.0006 0.0024
Mycobacterium ulcerans lipase LipD 0.0035 0.0085 0.0421
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0098 0.0402 0.0437
Trichomonas vaginalis taga, putative 0.0055 0.0184 0.0721
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0109 0.0544
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0055 0.0184 0.0721
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0022 0.0085
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0119 0.051 0.0554
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.003 0.0059 0.0281
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0043 0.0127 0.0127
Trichomonas vaginalis set domain proteins, putative 0.0466 0.2265 0.885
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0022 0.0085
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0031 0.0034
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0055 0.0184 0.0721
Echinococcus multilocularis Ankyrin 0.0023 0.0027 0.0029
Echinococcus granulosus chromobox protein 1 0.0081 0.0317 0.0317
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0098 0.0402 0.0437
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0009 0.0009
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0052 0.0057
Onchocerca volvulus 0.0393 0.1897 0.2058
Onchocerca volvulus 0.0027 0.0044 0.0047
Brugia malayi Tachykinin-like peptides receptor 99D 0.002 0.0009 0.0009
Brugia malayi gonadotropin-releasing hormone receptor 2 0.002 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0024 0.0031 0.0135
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0022 0.0085
Giardia lamblia Hypothetical protein 0.0023 0.0024 0.0084
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0085
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0043 0.0127 0.0138
Brugia malayi ecdysteroid receptor 0.0098 0.0402 0.0437
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1167 0.4562
Onchocerca volvulus 0.002 0.0009 0.0008
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0044 0.0047
Echinococcus granulosus pyruvate kinase 0.0033 0.0073 0.0073
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0085 0.0085
Trypanosoma brucei multidrug resistance-associated protein, putative 0.003 0.0059 0.0281
Mycobacterium ulcerans epoxide hydrolase EphA 0.0158 0.0705 0.3698
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0085 0.0093
Brugia malayi Cytochrome P450 family protein 0.0033 0.0076 0.0082
Schistosoma mansoni hypothetical protein 0.0023 0.0026 0.0028
Plasmodium falciparum nitric oxide synthase, putative 0.0026 0.0039 0.02
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0137 0.0599 0.065
Onchocerca volvulus 0.0027 0.0044 0.0047
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.002 0.0009 0.0008
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0059 0.0205 0.0223
Brugia malayi nuclear hormone receptor 0.0046 0.0141 0.0154
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0154
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0098 0.0402 0.0437
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.016 0.0626
Toxoplasma gondii transporter, major facilitator family protein 0.0027 0.0044 0.0227
Schistosoma mansoni histamine h1 receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0031 0.0064 0.0069
Schistosoma mansoni multidrug resistance protein 0.0019 0.0006 0.0006
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0024 0.0031 0.0031
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0043 0.0127 0.0138
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0022 0.0085
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.0407 0.1966 0.2134
Echinococcus multilocularis FTZ F1 alpha 0.0098 0.0402 0.0437
Schistosoma mansoni amine GPCR 0.002 0.0009 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0024 0.0031 0.0135
Brugia malayi Calcium binding EGF domain containing protein 0.0334 0.1596 0.1732
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0009 0.0009
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.002 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0024 0.0031 0.0135
Onchocerca volvulus 0.002 0.0009 0.0008
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0024 0.0031 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.016 0.0626
Echinococcus granulosus g protein coupled receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) phosphatidylinositol 3 0.0061 0.0216 0.0235
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0053 0.0177 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0127 0.0496
Echinococcus multilocularis neuropeptide FF receptor 2 0.002 0.0009 0.0009
Schistosoma mansoni smdr1 0.0019 0.0006 0.0006
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.002 0.0009 0.0009
Brugia malayi G-protein coupled receptor 0.002 0.0009 0.0009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0022 0.0085
Brugia malayi Calcium binding EGF domain containing protein 0.0334 0.1596 0.1732
Echinococcus multilocularis phd:f box containing protein 0.0024 0.0031 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0116 0.0452
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0093
Onchocerca volvulus 0.0054 0.0184 0.0198
Schistosoma mansoni tyrosine kinase 0.0076 0.0295 0.032
Brugia malayi Pre-SET motif family protein 0.041 0.1979 0.2147
Brugia malayi hypothetical protein 0.0122 0.0526 0.0571
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0109 0.0573
Brugia malayi notch-like transmembrane receptor 0.0334 0.1596 0.1732
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0076 0.037
Schistosoma mansoni hypothetical protein 0.0334 0.1596 0.1732
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0061 0.0216 0.1141
Loa Loa (eye worm) multidrug resistance protein 3 0.0055 0.0184 0.02
Echinococcus granulosus nuclear receptor nhr 48 0.0046 0.0141 0.0141
Schistosoma mansoni microsomal glutathione s-transferase 0.0093 0.038 0.0412
Schistosoma mansoni septate junction protein 0.0334 0.1596 0.1732
Entamoeba histolytica hypothetical protein 0.0123 0.0529 0.2068
Schistosoma mansoni opsin-like receptor 0.002 0.0009 0.0009
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0055 0.0184 0.0944
Loa Loa (eye worm) hypothetical protein 0.0052 0.0169 0.0184
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0055 0.0184 0.0966
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0024 0.0031 0.0135
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.002 0.0009 0.0009
Giardia lamblia Fructose-bisphosphate aldolase 0.0524 0.2559 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0059 0.0064
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0093
Echinococcus granulosus pyruvate kinase 0.0033 0.0073 0.0073
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0085 0.0093
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0049 0.0156 0.091
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0009 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0009 0.0009
Trypanosoma cruzi aldo/keto reductase, putative 0.0172 0.0778 0.41
Schistosoma mansoni jumonji/arid domain-containing protein 0.0091 0.0369 0.0401
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0035 0.0087 0.046
Loa Loa (eye worm) hypothetical protein 0.0345 0.1653 0.1794
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Plasmodium falciparum heterochromatin protein 1 0.0022 0.0022 0.0097
Onchocerca volvulus 0.0035 0.0085 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0071 0.0277
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0041 0.0215
Brugia malayi hypoxia-induced factor 1 0.0421 0.2038 0.2211
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0022 0.0022 0.0097
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0024 0.0031 0.0135
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0029 0.0055 0.0261
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0055 0.0184 0.0721
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.041 0.1979 0.2147
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0055 0.0184 0.02
Giardia lamblia PHD finger protein 15 0.0028 0.0052 0.0195
Brugia malayi hypothetical protein 0.0044 0.0132 0.0143
Schistosoma mansoni glucose transport protein 0.0047 0.0147 0.016
Schistosoma mansoni netrin receptor unc5 0.0023 0.0026 0.0028
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0393 0.1897 0.2059
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0093
Schistosoma mansoni RAR-like nuclear receptor 0.0098 0.0402 0.0437
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0024 0.0031 0.0135
Trichomonas vaginalis aldo/keto reductase, putative 0.0393 0.1897 0.7413
Schistosoma mansoni cell polarity protein 0.0334 0.1596 0.1732
Echinococcus granulosus aldehyde reductase 0.0221 0.1028 0.1028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0176 0.09
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Leishmania major p-glycoprotein e 0.003 0.0059 0.0281
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0061 0.0216 0.0846
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0035 0.0087 0.046
Loa Loa (eye worm) hypothetical protein 0.0059 0.0205 0.0223
Echinococcus multilocularis expressed protein 0.0058 0.02 0.0217
Brugia malayi neuropeptide F receptor 0.002 0.0009 0.0009
Mycobacterium tuberculosis Conserved protein 0.0172 0.0778 0.4082
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0121 0.0522 0.0567
Plasmodium falciparum LCCL domain-containing protein 0.0054 0.0184 0.108
Trichomonas vaginalis chromobox protein, putative 0.0053 0.0177 0.0692
Mycobacterium ulcerans glyoxalase GloA 0.008 0.0312 0.162
Loa Loa (eye worm) nuclear receptor NHR-67 0.0046 0.0141 0.0154
Brugia malayi Serotonin receptor 0.002 0.0009 0.0009
Schistosoma mansoni multidrug resistance protein 0.003 0.0059 0.0064
Brugia malayi Valyl-tRNA synthetase 0.0022 0.0022 0.0024
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0073 0.0285
Brugia malayi SPARC precursor 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Brugia malayi Cytochrome P450 family protein 0.0081 0.0318 0.0345
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0295 0.1398 0.7362
Brugia malayi multidrug resistance related protein 1 0.003 0.0059 0.0064
Echinococcus multilocularis jumonji domain containing 1A 0.0024 0.0031 0.0034
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0009 0.0009
Schistosoma mansoni aldo-keto reductase 0.0393 0.1897 0.2059
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0073 0.0355
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0026 0.0039 0.0039
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0062 0.0322
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0172 0.0778 0.4686
Plasmodium falciparum aldo-keto reductase, putative 0.0172 0.0778 0.4686
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0118 0.0622
Echinococcus multilocularis agrin 0.0018 0.0001 0.0001
Trichomonas vaginalis aldo-keto reductase, putative 0.0172 0.0778 0.3039
Loa Loa (eye worm) carboxylesterase 0.0182 0.0828 0.0899
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0026 0.0039 0.0042
Echinococcus granulosus jumonji domain containing 1A 0.0024 0.0031 0.0031
Echinococcus granulosus fmrfamide receptor 0.002 0.0009 0.0009
Schistosoma mansoni smdr2 0.0055 0.0184 0.02
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.002 0.0009 0.0009
Schistosoma mansoni amine GPCR 0.002 0.0009 0.0009
Brugia malayi hypothetical protein 0.0054 0.0184 0.0199
Loa Loa (eye worm) hypothetical protein 0.0029 0.0056 0.006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0085
Loa Loa (eye worm) hypothetical protein 0.003 0.006 0.0065
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0024 0.0031 0.0135
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0024 0.0031 0.0135
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0393 0.1897 0.2059
Brugia malayi secreted modular calcium-binding protein 1 0.0018 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.008 0.0312 0.162
Echinococcus granulosus neuropeptide s receptor 0.0464 0.2251 0.2251
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0038 0.0041
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0085 0.0334
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0193 0.0883 0.0883
Brugia malayi GnHR receptor homolog 0.002 0.0009 0.0009
Echinococcus multilocularis carboxylesterase 5A 0.0182 0.0828 0.0899
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0098 0.0402 0.0437
Brugia malayi flavodoxin family protein 0.0026 0.0039 0.0042
Echinococcus granulosus neurogenic locus notch protein 0.0334 0.1596 0.1596
Echinococcus granulosus neuropeptide receptor 0.002 0.0009 0.0009
Onchocerca volvulus 0.002 0.0009 0.0008
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0024 0.0031 0.0135
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0009 0.0009
Schistosoma mansoni 4-hydroxyphenylpyruvate dioxygenase 0.008 0.0312 0.0339
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0034 0.0079 0.0387
Mycobacterium ulcerans putative regulatory protein 0.0101 0.0418 0.2177
Schistosoma mansoni amine GPCR 0.002 0.0009 0.0009
Brugia malayi Doublecortin family protein 0.0054 0.0184 0.0199
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0022 0.0024
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0062 0.0343
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0055 0.0184 0.0721
Echinococcus granulosus peroxidasin 0.1841 0.9215 0.9215
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0085 0.0093
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0009 0.0009
Brugia malayi Protein cec-1. 0.0022 0.0022 0.0024
Echinococcus granulosus G protein coupled receptor 139 0.002 0.0009 0.0009
Brugia malayi ABC transporter 0.0019 0.0006 0.0006
Trichomonas vaginalis abcb9, putative 0.0055 0.0184 0.0721
Brugia malayi chromobox protein homolog 3 0.005 0.0162 0.0176
Onchocerca volvulus Peroxidasin homolog 0.1841 0.9215 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0524 0.2559 1
Brugia malayi jmjC domain containing protein 0.0024 0.0031 0.0034
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0024 0.0031 0.0135
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0061 0.0216 0.0235
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0085 0.0421
Schistosoma mansoni hypothetical protein 0.0205 0.0943 0.1023
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0098 0.0402 0.0402
Schistosoma mansoni pyruvate kinase 0.0033 0.0073 0.0079
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0393 0.1897 0.1897
Echinococcus multilocularis fatty acid binding protein FABP2 0.0033 0.0077 0.0083
Schistosoma mansoni zinc finger protein 0.0046 0.0141 0.0154
Entamoeba histolytica alcohol dehydrogenase, putative 0.0172 0.0778 0.3039
Giardia lamblia MRP-like ABC transporter 0.003 0.0059 0.0221
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0072 0.0281
Echinococcus granulosus intermediate filament protein 0.0053 0.0177 0.0177
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0184 0.0721
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0036 0.009 0.0353
Trichomonas vaginalis hypothetical protein 0.0022 0.0022 0.0085
Brugia malayi ecdysone receptor 0.0046 0.0141 0.0154
Brugia malayi PAS domain containing protein 0.0136 0.0596 0.0647
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.0022 0.0097
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.1398 0.737
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.4857 0.5271
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0025
Schistosoma mansoni hypothetical protein 0.0334 0.1596 0.1732
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Brugia malayi glutathione reductase 0.0047 0.0148 0.0161
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0154
Schistosoma mansoni nuclear receptor 0.0046 0.0141 0.0154
Mycobacterium tuberculosis Conserved protein TB27.3 0.008 0.0312 0.162
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0524 0.2559 1
Brugia malayi hypothetical protein 0.0123 0.0529 0.0574
Brugia malayi Furin-like cysteine rich region family protein 0.0144 0.0635 0.069
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.0456 0.2378
Onchocerca volvulus Alhambra homolog 0.0028 0.0052 0.0055
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.0517 0.2701
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.003 0.0059 0.0305
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0044 0.0048
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0026 0.0039 0.0204
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0018 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0024 0.0031 0.0135
Onchocerca volvulus 0.0393 0.1897 0.2058
Onchocerca volvulus Putative cubilin 0.0334 0.1596 0.1731
Schistosoma mansoni alpha-1 adrenergic receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0098 0.0402 0.0437
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.003 0.0059 0.0281
Schistosoma mansoni hypothetical protein 0.0028 0.0052 0.0057
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0035 0.0087 0.0095
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0062 0.0328
Brugia malayi hypothetical protein 0.002 0.0009 0.0009
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0054 0.0181 0.0181
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0022 0.0085
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0118 0.0593
Echinococcus multilocularis Chromobox protein 3 0.0022 0.0022 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0109 0.0544
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0393 0.1897 0.2059
Mycobacterium tuberculosis Probable reductase 0.0108 0.0456 0.2378
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0154
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0082 0.0324 0.0351
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0024 0.0031 0.0135
Loa Loa (eye worm) animal heme peroxidase 0.1841 0.9215 1
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0093
Echinococcus multilocularis g protein coupled receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) ABC transporter 0.0019 0.0006 0.0006
Schistosoma mansoni glucose transport protein 0.0047 0.0147 0.016
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Schistosoma mansoni nuclear hormone receptor 0.0098 0.0402 0.0437
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0055 0.0184 0.02
Loa Loa (eye worm) hypothetical protein 0.0035 0.0085 0.0093
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0172 0.0778 0.0844
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0098 0.0402 0.0437
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0121 0.0522 0.0522
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0036
Echinococcus granulosus notch 0.0334 0.1596 0.1596
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0109 0.0461 0.05
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0022 0.0085
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.002 0.0009 0.0009
Brugia malayi putative neuropeptide receptor NPR1 0.002 0.0009 0.0009
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0009 0.0009
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0085 0.0421
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0048 0.0153 0.0805
Loa Loa (eye worm) helicase 0.0022 0.0022 0.0024
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0061 0.0216 0.0235
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0317 0.1241
Brugia malayi multidrug resistance protein 3 0.0055 0.0184 0.02
Echinococcus multilocularis transfer RNA-Lys 0.0101 0.0418 0.0453
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0019 0.0002 0.001
Brugia malayi nuclear receptor NHR-88 0.0046 0.0141 0.0154
Brugia malayi PHD-finger family protein 0.0028 0.0052 0.0057
Trichomonas vaginalis abcb9, putative 0.0055 0.0184 0.0721
Brugia malayi nuclear hormone receptor family member nhr-6 0.0046 0.0141 0.0154
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0524 0.2559 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.002 0.0008 0.0031
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0028 0.0052 0.0057
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0009 0.0009
Schistosoma mansoni fatty acid binding protein 0.0033 0.0077 0.0083
Entamoeba histolytica P-glycoprotein-2 0.0055 0.0184 0.0721
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0158 0.0705 0.3698
Plasmodium falciparum phd finger protein, putative 0.0028 0.0052 0.0282
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0026 0.0039 0.0042
Echinococcus multilocularis aldo keto reductase 0.0393 0.1897 0.2059
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0049 0.0156 0.0169
Brugia malayi hypothetical protein 0.002 0.0009 0.0009
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0047 0.0144 0.0751
Loa Loa (eye worm) hypothetical protein 0.0039 0.0106 0.0115
Trypanosoma cruzi target of rapamycin kinase 3 0.0052 0.0172 0.0905
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0009 0.0009
Brugia malayi Calcitonin receptor-like protein seb-1 0.0137 0.0599 0.065
Onchocerca volvulus 0.002 0.0009 0.0008
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0055 0.0184 0.0966
Echinococcus multilocularis aldo keto reductase 0.0393 0.1897 0.2059
Trichomonas vaginalis esterase, putative 0.0035 0.0085 0.0334
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Schistosoma mansoni cytochrome P450 reductase 0.0026 0.0039 0.0042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0524 0.2559 1
Echinococcus granulosus FTZ F1 alpha 0.0098 0.0402 0.0402
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Echinococcus granulosus lamin dm0 0.0053 0.0177 0.0177
Leishmania major cathepsin L-like protease 0.0053 0.0176 0.09
Brugia malayi tailless protein 0.0046 0.0141 0.0154
Echinococcus multilocularis slit 2 protein 0.0334 0.1596 0.1732
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0154
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0176 0.09
Echinococcus granulosus g protein coupled receptor 0.002 0.0009 0.0009
Onchocerca volvulus 0.0047 0.0144 0.0155
Leishmania major p-glycoprotein 0.0055 0.0184 0.0944
Echinococcus multilocularis peroxidasin 0.1841 0.9215 1
Trypanosoma cruzi aldo/keto reductase, putative 0.0393 0.1897 1
Brugia malayi Carboxylesterase family protein 0.0031 0.0064 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0176 0.09
Schistosoma mansoni hypothetical protein 0.0047 0.0147 0.016
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0009 0.0009
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0047 0.0147 0.0147
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0393 0.1897 0.1897
Loa Loa (eye worm) hypothetical protein 0.0054 0.0184 0.0199
Onchocerca volvulus 0.1841 0.9215 1
Brugia malayi Peroxidasin 0.1841 0.9215 1
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0024 0.0031 0.0135
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0008 0.0011
Entamoeba histolytica hypothetical protein 0.003 0.0059 0.0231
Onchocerca volvulus Bile acid receptor homolog 0.0098 0.0402 0.0435
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0034 0.0079 0.0444
Brugia malayi hypothetical protein 0.002 0.0009 0.0009
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0031 0.0064 0.0307
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Plasmodium falciparum glyoxalase I 0.0345 0.1653 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0072 0.0078
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0009 0.0009
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0061 0.0216 0.1113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0176 0.09
Mycobacterium tuberculosis Conserved protein 0.0035 0.0085 0.0421
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0058 0.02 0.1048
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0044 0.0044
Schistosoma mansoni lipoxygenase 0.0326 0.1555 0.1688
Plasmodium falciparum thioredoxin reductase 0.0047 0.0148 0.0865
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0154
Schistosoma mansoni opsin-like receptor 0.002 0.0009 0.0009
Echinococcus granulosus Nuclear hormone receptor HR96 0.0046 0.0141 0.0141
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0052 0.0057
Giardia lamblia Aldose reductase 0.0393 0.1897 0.7411
Echinococcus multilocularis follistatin 0.0018 0.0001 0.0001
Echinococcus granulosus multidrug resistance protein 1 0.0036 0.009 0.009
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0098 0.0402 0.0437
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0046 0.0141 0.0154
Leishmania major phosphatidylinositol kinase related protein, putative 0.002 0.0012 0.0031
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.003 0.0059 0.0064
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Brugia malayi hypothetical protein 0.0027 0.0044 0.0048
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0177 0.0192
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.002 0.0009 0.0009
Schistosoma mansoni peptide (allatostatin)-like receptor 0.002 0.0009 0.0009
Entamoeba histolytica P-glycoprotein 5, putative 0.0019 0.0002 0.001
Brugia malayi SET domain containing protein 0.0025 0.0033 0.0036
Brugia malayi latrophilin 2 splice variant baaae 0.0093 0.0381 0.0413
Trypanosoma cruzi major cysteine proteinase, putative 0.0042 0.0119 0.0626
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0052 0.0172 0.0877
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0058 0.02 0.0217
Brugia malayi Protein kinase domain containing protein 0.0046 0.0141 0.0153
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0393 0.1897 0.7413
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Entamoeba histolytica P-glycoprotein-5 0.0055 0.0184 0.0721
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0058 0.02 0.1178
Onchocerca volvulus 0.002 0.0009 0.0008
Schistosoma mansoni opsin-like receptor 0.002 0.0009 0.0009
Mycobacterium tuberculosis Conserved protein 0.008 0.0312 0.162
Brugia malayi orphan nuclear receptor NR2E1 0.0046 0.0141 0.0154
Brugia malayi Cadherin domain containing protein 0.0334 0.1596 0.1732
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0035 0.0087 0.0341
Plasmodium falciparum multidrug resistance protein 1 0.0055 0.0184 0.1084
Brugia malayi beta-lactamase 0.0035 0.0085 0.0093
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0009 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0109 0.0544
Echinococcus multilocularis ATP binding cassette sub family B 0.0019 0.0006 0.0006
Brugia malayi Carboxylesterase family protein 0.0182 0.0828 0.0899
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0061 0.0216 0.0846
Loa Loa (eye worm) hypothetical protein 0.0027 0.0044 0.0048
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Echinococcus granulosus Chromo domain 0.0022 0.0022 0.0022
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0046 0.0141 0.0154
Onchocerca volvulus 0.0334 0.1596 0.1731
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0031 0.0064 0.0307
Loa Loa (eye worm) hypothetical protein 0.0334 0.1596 0.1732
Echinococcus multilocularis neurogenic locus notch protein 0.0334 0.1596 0.1732
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0034 0.0079 0.0387
Brugia malayi Dopamine receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0154
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0109 0.0573
Brugia malayi polk-prov protein 0.003 0.006 0.0065
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0009 0.0009
Brugia malayi Heterochromatin protein 1 0.0081 0.0317 0.0345
Giardia lamblia High cysteine protein 0.0334 0.1596 0.6235
Schistosoma mansoni hypothetical protein 0.0205 0.0943 0.1023
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0034 0.0079 0.0416
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0169 0.0184
Schistosoma mansoni tyrosine kinase 0.0046 0.0141 0.0153
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0256 0.1203 0.6331
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0009 0.0009
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.0456 0.2378
Loa Loa (eye worm) blistered cuticle protein 3 0.1841 0.9215 1
Mycobacterium leprae putative cytochrome p450 0.0024 0.0031 0.0135
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0035 0.0087 0.0341
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0009 0.0009
Entamoeba histolytica P-glycoprotein 5, putative 0.0055 0.0184 0.0721
Brugia malayi Animal haem peroxidase family protein 0.1841 0.9215 1
Brugia malayi EGF-like domain containing protein 0.0334 0.1596 0.1732
Schistosoma mansoni thyroid hormone receptor 0.0219 0.1016 0.1103
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0098 0.0402 0.0437
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0393 0.1897 0.2059
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0009 0.0009
Echinococcus granulosus ATP binding cassette sub family B 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0052 0.0169 0.0184
Echinococcus granulosus BC026374 protein S09 family 0.0031 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0098 0.0402 0.0402
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0082 0.0324 0.0351
Mycobacterium ulcerans hypothetical protein 0.008 0.0312 0.162
Onchocerca volvulus 0.002 0.0009 0.0008
Entamoeba histolytica hypothetical protein 0.0123 0.0529 0.2068
Loa Loa (eye worm) ABC transporter 0.0019 0.0006 0.0006
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0148 0.0753
Echinococcus multilocularis Chromo domain 0.0022 0.0022 0.0024
Leishmania major hypothetical protein, conserved 0.003 0.0062 0.0298
Toxoplasma gondii ABC transporter family protein 0.0019 0.0006 0.0024
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0098 0.0402 0.0437
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0123 0.0529 0.0574
Echinococcus multilocularis GPCR, family 2 0.0043 0.0127 0.0138
Brugia malayi jmjC domain containing protein 0.0091 0.0369 0.0401
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0047 0.0147 0.016
Entamoeba histolytica P-glycoprotein-1 0.0055 0.0184 0.0721
Onchocerca volvulus 0.0393 0.1897 0.2058
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0019 0.0002 0.0003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0009 0.0009
Entamoeba histolytica P-glyco protein 6, putative 0.0055 0.0184 0.0721
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0082 0.0324 0.0351
Entamoeba histolytica hypothetical protein 0.0022 0.0022 0.0085
Trichomonas vaginalis aldo-keto reductase, putative 0.0172 0.0778 0.3039
Echinococcus multilocularis netrin receptor unc 5 0.0023 0.0026 0.0028
Loa Loa (eye worm) carboxylesterase 0.0031 0.0064 0.0069
Loa Loa (eye worm) oxidoreductase 0.0393 0.1897 0.2059
Brugia malayi GCC2 and GCC3 family protein 0.0334 0.1596 0.1732
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0141 0.0154
Loa Loa (eye worm) 4-hydroxyphenylpyruvate dioxygenase 0.008 0.0312 0.0339
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0019 0.0006 0.0024
Schistosoma mansoni chromobox protein 0.0022 0.0022 0.0024
Loa Loa (eye worm) oxidoreductase 0.0393 0.1897 0.2059
Echinococcus multilocularis neuropeptide s receptor 0.0464 0.2251 0.2443
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0026 0.0039 0.0174
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0052 0.0052
Brugia malayi lactoylglutathione lyase 0.0345 0.1653 0.1794
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0024 0.0031 0.0135
Echinococcus granulosus microsomal glutathione S transferase 3 0.0093 0.038 0.038
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0023 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0022 0.0085
Echinococcus multilocularis fmrfamide receptor 0.002 0.0009 0.0009
Schistosoma mansoni microtubule-associated protein tau 0.0666 0.3272 0.3551
Echinococcus multilocularis insulin receptor 0.0046 0.0141 0.0153
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0393 0.1897 0.1897
Brugia malayi Dopamine receptor protein 2 0.002 0.0009 0.0009
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0071 0.0373
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0026 0.0039 0.0174
Schistosoma mansoni hypothetical protein 0.0334 0.1596 0.1732
Onchocerca volvulus Chorion peroxidase homolog 0.1841 0.9215 1
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0062 0.0343
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0076 0.0399
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0024 0.0031 0.0135
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0393 0.1897 0.1897
Schistosoma mansoni jumonji domain containing protein 0.0024 0.0031 0.0034
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0024 0.0031 0.0135
Schistosoma mansoni hypothetical protein 0.0054 0.0184 0.0199
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0393 0.1897 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0054 0.0181 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0115 0.0451
Loa Loa (eye worm) hypothetical protein 0.0039 0.0106 0.0115
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0009 0.0009
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0055 0.0184 0.0184
Brugia malayi jmjC domain containing protein 0.0024 0.0031 0.0034
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0008 0.0011
Schistosoma mansoni peroxidasin 0.1841 0.9215 1
Brugia malayi Delta serrate ligand family protein 0.0334 0.1596 0.1732
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0024 0.0031 0.0135
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.015 0.0666 0.0666
Loa Loa (eye worm) hypothetical protein 0.0031 0.0064 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0071 0.0277
Schistosoma mansoni tyrosine kinase 0.0076 0.0295 0.032
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0393 0.1897 0.1897
Echinococcus granulosus slit 2 protein 0.0334 0.1596 0.1596
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0044 0.0048
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0022 0.0085
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0082 0.0324 0.0351
Onchocerca volvulus 0.002 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0029
Brugia malayi hypothetical protein 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0052 0.0169 0.0184
Plasmodium falciparum glutathione reductase 0.0047 0.0148 0.0865
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0055 0.0184 0.0721
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.002 0.0009 0.0009
Mycobacterium tuberculosis Cadmium inducible protein CadI 0.008 0.0312 0.162
Loa Loa (eye worm) animal heme peroxidase 0.1841 0.9215 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Schistosoma mansoni neuropeptide receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0205 0.0223
Loa Loa (eye worm) hypothetical protein 0.0052 0.0169 0.0184
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0085 0.0421
Schistosoma mansoni biogenic amine receptor 0.002 0.0009 0.0009
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0085 0.0334
Onchocerca volvulus 0.0035 0.0085 0.0091
Echinococcus multilocularis ecdysone induced protein 78C 0.0098 0.0402 0.0437
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Onchocerca volvulus 0.0031 0.0064 0.0068
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0089 0.035
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.002 0.0008 0.0011
Treponema pallidum fructose-bisphosphate aldolase 0.0524 0.2559 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0082 0.0324 0.0351
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Echinococcus granulosus RUN 0.0054 0.0184 0.0184
Brugia malayi hypothetical protein 0.002 0.0009 0.0009
Trypanosoma brucei aldo/keto reductase, putative 0.0172 0.0778 0.4082
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0023 0.0025
Echinococcus granulosus multidrug resistance protein 1 0.0055 0.0184 0.0184
Loa Loa (eye worm) TK/INSR protein kinase 0.0046 0.0141 0.0153
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Echinococcus granulosus dna polymerase kappa 0.004 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Onchocerca volvulus 0.002 0.0009 0.0008
Mycobacterium ulcerans hypothetical protein 0.008 0.0312 0.162
Loa Loa (eye worm) hypothetical protein 0.0093 0.0381 0.0413
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0085
Schistosoma mansoni rab6-interacting 0.0054 0.0184 0.0199
Toxoplasma gondii non-specific serine/threonine protein kinase 0.002 0.001 0.0049
Onchocerca volvulus 0.0053 0.0177 0.019
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0154
Schistosoma mansoni agrin 0.0018 0.0001 0.0001
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0047 0.0147 0.016
Entamoeba histolytica ATP-binding cassette protein, putative 0.003 0.0059 0.0231
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0046 0.0141 0.0154
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.1039 0.5462
Trichomonas vaginalis aldo-keto reductase, putative 0.0393 0.1897 0.7413
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0011 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0009 0.0009
Brugia malayi Associated with TFs and helicases family protein 0.0022 0.0022 0.0024
Schistosoma mansoni lamin 0.0053 0.0177 0.0192
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0022 0.0022 0.0024
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0024 0.0031 0.0135
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0182 0.0828 0.0899
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0031 0.0064 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0216 0.0846
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0049 0.0156 0.0169
Echinococcus multilocularis fat cadherin tumor suppressor 0.0334 0.1596 0.1732
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0098 0.0402 0.0437
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Echinococcus granulosus multidrug resistance associated protein 1 0.003 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0001
Toxoplasma gondii glyoxalase family protein 0.008 0.0312 0.164
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0044 0.0044
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0022 0.0085
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0024 0.0031 0.0135
Echinococcus multilocularis multidrug resistance associated protein 1 0.003 0.0059 0.0064
Schistosoma mansoni ap endonuclease 0.0034 0.0079 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0098 0.0402 0.0437
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0009 0.0009
Echinococcus granulosus peregrin 0.0028 0.0052 0.0052
Echinococcus multilocularis serotonin receptor 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0046 0.0141 0.0154
Schistosoma mansoni tyrosine kinase 0.0144 0.0635 0.069
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0073 0.0355
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0082 0.0324 0.0351
Entamoeba histolytica acyl-coA synthetase, putative 0.002 0.0008 0.0031
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0034 0.0079 0.0079
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0043 0.0127 0.0138
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0085 0.0421
Schistosoma mansoni multidrug resistance protein 0.0019 0.0002 0.0003
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0073 0.0355
Toxoplasma gondii cytochrome p450 superfamily protein 0.0024 0.0031 0.0159
Loa Loa (eye worm) latrophilin receptor protein 2 0.0043 0.0127 0.0138
Leishmania major cytochrome p450-like protein 0.0033 0.0076 0.037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0089 0.035
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0024 0.0031 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0049 0.019
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.002 0.0009 0.0009
Schistosoma mansoni multidrug resistance protein 0.003 0.0059 0.0064
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0031 0.0064 0.0069
Echinococcus granulosus aldo keto reductase 0.0393 0.1897 0.1897
Onchocerca volvulus 0.0035 0.0085 0.0091
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0052 0.0169 0.0184
Brugia malayi hypothetical protein 0.0047 0.0144 0.0156
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Schistosoma mansoni coup transcription factor 0.0098 0.0402 0.0437
Echinococcus granulosus tachykinin peptides receptor 99D 0.002 0.0009 0.0009
Entamoeba histolytica P-glycoprotein 6, putative 0.0019 0.0006 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1167 0.4562
Loa Loa (eye worm) oxidoreductase 0.0047 0.0144 0.0156
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0019 0.0006 0.0031
Onchocerca volvulus 0.0054 0.0184 0.0198
Brugia malayi Steroid receptor seven-up type 2 0.0098 0.0402 0.0437
Schistosoma mansoni hypothetical protein 0.0043 0.0127 0.0138
Loa Loa (eye worm) MH2 domain-containing protein 0.0099 0.041 0.0445
Schistosoma mansoni chromobox protein 0.0022 0.0022 0.0024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0524 0.2559 1
Giardia lamblia Multidrug resistance-associated protein 1 0.0029 0.0056 0.0208
Loa Loa (eye worm) hypothetical protein 0.1841 0.9215 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0109 0.0544
Entamoeba histolytica ATP-binding cassette protein, putative 0.003 0.0059 0.0231
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0047 0.0144 0.0156
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0071 0.0277
Loa Loa (eye worm) hypothetical protein 0.0355 0.17 0.1845
Entamoeba histolytica P-glycoprotein 6, putative 0.0019 0.0006 0.0023
Onchocerca volvulus 0.002 0.0009 0.0008
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0049 0.0156 0.0169
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Mycobacterium ulcerans hypothetical protein 0.008 0.0312 0.162
Mycobacterium leprae Conserved hypothetical protein 0.0024 0.0031 0.0135
Echinococcus granulosus fibropellin Ia 0.0334 0.1596 0.1596
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0024 0.0031 0.0135
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0098 0.0402 0.0402
Onchocerca volvulus 0.002 0.0009 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0098 0.0402 0.0437
Brugia malayi Bromodomain containing protein 0.0028 0.0052 0.0057
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0031 0.0165
Giardia lamblia Multidrug resistance-associated protein 1 0.003 0.0059 0.0221
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0109 0.0573
Toxoplasma gondii thioredoxin reductase 0.0047 0.0148 0.0776
Echinococcus granulosus epidermal growth factor receptor 0.0077 0.0299 0.0299
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0058 0.02 0.1178
Plasmodium falciparum pyruvate kinase 0.0033 0.0073 0.0408
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0035 0.0087 0.046
Brugia malayi hypothetical protein 0.0019 0.0006 0.0006
Onchocerca volvulus 0.1841 0.9215 1
Echinococcus granulosus nuclear factor of activated T cells 5 0.0119 0.051 0.051
Schistosoma mansoni neuropeptide f receptor 76f 0.002 0.0009 0.0009
Schistosoma mansoni protein phosphatase 2C 0.0024 0.0031 0.0034
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0393 0.1897 0.2059
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0148 0.0161
Schistosoma mansoni myosin xvIII 0.002 0.0009 0.0009
Mycobacterium ulcerans glyoxalase GloA 0.008 0.0312 0.162
Mycobacterium ulcerans beta-lactamase 0.0035 0.0085 0.0421
Onchocerca volvulus 0.002 0.0009 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0085
Plasmodium vivax glyoxalase I, putative 0.008 0.0312 0.186
Echinococcus multilocularis neuropeptide receptor 0.002 0.0009 0.0009
Onchocerca volvulus 0.0334 0.1596 0.1731
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0109 0.0544
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0059 0.0205 0.0223
Brugia malayi NADH-dependent xylose reductase 0.0172 0.0778 0.0844
Trichomonas vaginalis aldo-keto reductase, putative 0.0393 0.1897 0.7413
Plasmodium falciparum aldehyde reductase, putative 0.0172 0.0778 0.4686
Brugia malayi hypothetical protein 0.002 0.0009 0.0009
Echinococcus multilocularis nuclear receptor nhr 48 0.0046 0.0141 0.0154

Activities

Activity type Activity value Assay description Source Reference
IC90 (functional) = 100 ug ml-1 Antileishmanial activity against Leishmania braziliensis 2903 ChEMBL. No reference
IC90 (functional) = 100 ug ml-1 Antitrypanosomal activity against Trypanosoma cruzi Tulahuen ChEMBL. No reference
Inhibition (functional) = 0 % Inhibitory activity against human T-lymphotropic virus type 1 (HTLV-1) infected HUT-102 cells at 10 microM. ChEMBL. 12617915
Inhibition (functional) = 0 % Antimicrobial activity against Candida albicans ATCC 10231 at 100 ug/ml after 24 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Candida albicans ATCC 10231 at 50 ug/ml after 24 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Candida albicans ATCC 10231 at 25 ug/ml after 24 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Candida albicans ATCC 10231 at 12.5 ug/ml after 24 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Candida albicans ATCC 10231 at 6.25 ug/ml after 24 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans ATCC 32264 at 6.25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 983040 isolate at 6.25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 972724 isolate at 6.25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 042074 isolate at 6.25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 983036 isolate at 25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 983036 isolate at 12.5 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 983036 isolate at 6.25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 00319 isolate at 12.5 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 00319 isolate at 6.25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 972751 isolate at 12.5 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 972751 isolate at 6.25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 031631 isolate at 6.25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 031706 isolate at 12.5 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 031706 isolate at 6.25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 961951 isolate at 12.5 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 961951 isolate at 6.25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 0 % Antimicrobial activity against Cryptococcus neoformans IM 052470 isolate at 6.25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 4 % Antimicrobial activity against Cryptococcus neoformans IM 983040 isolate at 12.5 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 5 % Antimicrobial activity against Cryptococcus neoformans IM 031631 isolate at 12.5 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 7 % Antimicrobial activity against Cryptococcus neoformans IM 042074 isolate at 12.5 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 10 % Antimicrobial activity against Cryptococcus neoformans IM 961951 isolate at 25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 12 % Antimicrobial activity against Cryptococcus neoformans IM 983036 isolate at 50 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 13 % Antimicrobial activity against Cryptococcus neoformans IM 983040 isolate at 25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 13 % Antimicrobial activity against Cryptococcus neoformans IM 972724 isolate at 12.5 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 14 % Antimicrobial activity against Cryptococcus neoformans IM 00319 isolate at 25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 15 % Antimicrobial activity against Cryptococcus neoformans IM 031631 isolate at 25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 17 % Antimicrobial activity against Cryptococcus neoformans IM 031706 isolate at 25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 21 % Antimicrobial activity against Cryptococcus neoformans IM 052470 isolate at 12.5 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 22 % Antimicrobial activity against Cryptococcus neoformans IM 972751 isolate at 25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 29 % Antimicrobial activity against Cryptococcus neoformans IM 983040 isolate at 50 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 32 % Antimicrobial activity against Cryptococcus neoformans ATCC 32264 at 12.5 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 32 % Antimicrobial activity against Cryptococcus neoformans IM 983036 isolate at 100 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 32 % Antimicrobial activity against Cryptococcus neoformans IM 961951 isolate at 50 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 33 % Antimicrobial activity against Cryptococcus neoformans IM 042074 isolate at 25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 34 % Antimicrobial activity against Cryptococcus neoformans IM 00319 isolate at 50 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 34 % Antimicrobial activity against Cryptococcus neoformans IM 031631 isolate at 50 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 35 % Antimicrobial activity against Cryptococcus neoformans IM 972724 isolate at 25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 35 % Antimicrobial activity against Cryptococcus neoformans IM 052470 isolate at 25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 45 % Antimicrobial activity against Cryptococcus neoformans IM 961951 isolate at 100 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 46 % Antimicrobial activity against Cryptococcus neoformans IM 031706 isolate at 50 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 47 % Antimicrobial activity against Cryptococcus neoformans IM 00319 isolate at 100 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 50 % Antimicrobial activity against Cryptococcus neoformans IM 983040 isolate at 100 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 54 % Antimicrobial activity against Cryptococcus neoformans IM 972751 isolate at 50 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 67 % Antimicrobial activity against Cryptococcus neoformans IM 031706 isolate at 100 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 74 % Antimicrobial activity against Cryptococcus neoformans IM 031631 isolate at 100 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 76 % Antimicrobial activity against Cryptococcus neoformans IM 052470 isolate at 50 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 77 % Antimicrobial activity against Cryptococcus neoformans ATCC 32264 at 25 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 77 % Antimicrobial activity against Cryptococcus neoformans IM 042074 isolate at 50 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 83 % Antimicrobial activity against Cryptococcus neoformans IM 972751 isolate at 100 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 84 % Antimicrobial activity against Cryptococcus neoformans IM 042074 isolate at 100 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 87 % Antimicrobial activity against Cryptococcus neoformans IM 972724 isolate at 50 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 88 % Antimicrobial activity against Cryptococcus neoformans IM 052470 isolate at 100 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 99 % Antimicrobial activity against Cryptococcus neoformans IM 972724 isolate at 100 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 100 % Antimicrobial activity against Cryptococcus neoformans ATCC 32264 at 100 ug/ml after 48 hrs ChEMBL. 18752959
Inhibition (functional) = 100 % Antimicrobial activity against Cryptococcus neoformans ATCC 32264 at 50 ug/ml after 48 hrs ChEMBL. 18752959
Ki (binding) > 35000 nM Binding affinity against N-methyl-D-aspartate glutamate receptor using [3H]-25-6981 as radioligand. ChEMBL. 12182873
Ki (binding) > 35000 nM Binding affinity against N-methyl-D-aspartate glutamate receptor using [3H]-25-6981 as radioligand. ChEMBL. 12182873
MIC (functional) = 31.2 ug ml-1 Antifungal activity against Cryptococcus neoformans ATCC 32264 after 48 hrs by broth microdilution technique ChEMBL. 18752959
MIC (functional) = 125 ug ml-1 Antifungal activity against Saccharomyces cerevisiae ATCC 9763 after 48 hrs by broth microdilution technique ChEMBL. 18752959
MIC (functional) = 250 ug ml-1 Antifungal activity against Candida albicans ATCC 10231 after 48 hrs by broth microdilution technique ChEMBL. 18752959
pKa (binding) = 5.2 The compound was tested for its binding affinity against N-methyl-D-aspartate glutamate receptor using potentiometric method. ChEMBL. 12182873
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS of Nrf2 Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5962 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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