Detailed information for compound 165698

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 400.508 | Formula: C24H32O5
  • H donors: 0 H acceptors: 0 LogP: 1.8 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: C1COC2(O1)CCC1C(=CCC3C1[C@H]1C[C@@]4([C@]5(C1)C3CCC15OCCO1)CO4)C2
  • InChi: 1S/C24H32O5/c1-2-18-19-4-6-24(27-9-10-28-24)23(19)13-16(11-21(23)14-29-21)20(18)17-3-5-22(12-15(1)17)25-7-8-26-22/h1,16-20H,2-14H2/t16-,17?,18?,19?,20?,21-,23-/m0/s1
  • InChiKey: JZGACHMDOXRHHL-LLTOKDNCSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0313 0.0499
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Onchocerca volvulus Big bang homolog 0.0009 0.0013 0.0013
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0174 0.2301 0.3702
Trichomonas vaginalis sulfite reductase, putative 0.0455 0.6207 0.6208
Brugia malayi PDZ domain containing protein 0.0009 0.0013 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.0178 0.0424
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0011 0.0032 0.0047
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0349 0.0553
Loa Loa (eye worm) hypothetical protein 0.0009 0.0005 0.0006
Loa Loa (eye worm) cytochrome b5 reductase 4 0.0052 0.06 0.0685
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.1478 0.2381
Loa Loa (eye worm) programmed cell death 8 0.0009 0.0005 0.0006
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0093 0.0144
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0403 0.5488 0.5489
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0165 0.0183
Schistosoma mansoni importin beta-1 0.003 0.0303 0.0484
Brugia malayi Thioredoxin reductase 0.0097 0.123 0.1402
Brugia malayi 6-phosphofructokinase 0.0115 0.1478 0.1685
Mycobacterium ulcerans electron transfer protein FdxB 0.0052 0.06 0.0967
Leishmania major hypothetical protein, conserved 0.0028 0.0275 0.0436
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.0178 0.0424
Echinococcus granulosus flap endonuclease GEN 1 0.0011 0.0032 0.0047
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0349 0.0557
Brugia malayi hypothetical protein 0.0121 0.1564 0.1784
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0009 0.0013 0.0016
Plasmodium vivax ferredoxin--NADP reductase, putative 0.0052 0.06 0.096
Chlamydia trachomatis sulfite reductase 0.0281 0.3788 1
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0349 0.0349
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0165 0.0392
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0032 0.0043
Schistosoma mansoni alkaline phosphatase 0.0352 0.4773 0.7688
Schistosoma mansoni sulfide quinone reductase 0.0009 0.0005 0.0004
Echinococcus multilocularis importin subunit beta 1 0.003 0.0303 0.0484
Echinococcus granulosus ligand of numb protein x 2 0.0009 0.0013 0.0016
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0349 0.0553
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0052 0.06 0.096
Loa Loa (eye worm) flavodoxin family protein 0.0174 0.2301 0.2623
Echinococcus granulosus pdz domain containing protein 0.0009 0.0013 0.0016
Trichomonas vaginalis protein phosphatase 2C, putative 0.0013 0.0058 0.0058
Brugia malayi glutamate synthase 0.0009 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0275 0.0903
Giardia lamblia hypothetical protein 0.0013 0.0058 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0165 0.0257
Plasmodium falciparum importin beta, putative 0.003 0.0303 0.0484
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0165 0.0257
Schistosoma mansoni sulfide quinone reductase 0.0009 0.0005 0.0004
Schistosoma mansoni cytochrome P450 reductase 0.0455 0.6207 1
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0192 0.0301
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0009 0.0005 0.0007
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0311 0.4203 1
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0053 0.0624 0.2058
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0009 0.0005 0.0007
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.1478 0.2375
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0174 0.2301 0.3704
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0455 0.6207 1
Treponema pallidum fructose-bisphosphate aldolase 0.0636 0.8728 1
Leishmania major NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0192 0.0219
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0052 0.06 0.096
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0352 0.4773 0.7688
Schistosoma mansoni multiple pdz domain protein 0.0009 0.0013 0.0016
Mycobacterium tuberculosis Probable oxidoreductase 0.0246 0.33 0.7853
Loa Loa (eye worm) hypothetical protein 0.0315 0.4268 0.4866
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0349 0.0562
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0053 0.0624 0.0997
Schistosoma mansoni lim domain 0.0009 0.0013 0.0016
Schistosoma mansoni cpg binding protein 0.0029 0.0278 0.0444
Entamoeba histolytica type A flavoprotein, putative 0.0174 0.2301 0.2632
Toxoplasma gondii exonuclease III APE 0.002 0.0158 0.0512
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0165 0.0266
Toxoplasma gondii flavodoxin domain-containing protein 0.0226 0.302 1
Entamoeba histolytica type A flavoprotein, putative 0.0174 0.2301 0.2632
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0009 0.0013 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0313 0.0313
Leishmania major DNA polymerase kappa, putative 0.002 0.0165 0.0257
Chlamydia trachomatis tail-specific protease 0.0009 0.0013 0.002
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0165 0.0188
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.0178 0.0287
Entamoeba histolytica type A flavoprotein, putative 0.0174 0.2301 0.2632
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0009 0.0005 0.0005
Plasmodium falciparum nitric oxide synthase, putative 0.0455 0.6207 1
Loa Loa (eye worm) glutathione reductase 0.0097 0.123 0.1402
Echinococcus multilocularis geminin 0.0341 0.4623 0.7446
Brugia malayi C2 domain containing protein 0.0009 0.0013 0.0015
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.0178 0.0287
Loa Loa (eye worm) CYP4Cod1 0.0031 0.0307 0.035
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0165 0.0261
Echinococcus multilocularis MAGUK p55 subfamily 0.0009 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0009 0.0003 0.0004
Brugia malayi XPG I-region family protein 0.0011 0.0032 0.0037
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0009 0.0013 0.0016
Brugia malayi Shank2E 0.0009 0.0013 0.0015
Loa Loa (eye worm) thioredoxin reductase 0.0097 0.123 0.1402
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.1478 0.2378
Schistosoma mansoni afadin (af-6 protein) 0.0009 0.0013 0.0016
Echinococcus granulosus amyloid beta A4 protein 0.0009 0.0013 0.0016
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0009 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Onchocerca volvulus 0.0009 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0009 0.0013 0.0016
Plasmodium vivax DNA repair protein RAD2, putative 0.0011 0.0032 0.0043
Plasmodium falciparum DNA repair protein RAD2, putative 0.0011 0.0032 0.0047
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0009 0.0005 0.0004
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0009 0.0013 0.0016
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0052 0.06 0.096
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0077 0.0115
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0636 0.8728 0.8729
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0078 0.0963 0.1547
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0455 0.6207 1
Mycobacterium ulcerans NADH dehydrogenase 0.0009 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0092 0.1164 0.1327
Trypanosoma cruzi trypanothione reductase, putative 0.0097 0.123 0.1974
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0165 0.0257
Schistosoma mansoni hypothetical protein 0.0341 0.4623 0.7446
Plasmodium falciparum thioredoxin reductase 0.0097 0.123 0.1977
Echinococcus granulosus multiple pdz domain protein 0.0009 0.0013 0.0016
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0093 0.0144
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0178 0.0279
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.1478 0.3509
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.1478 0.1478
Schistosoma mansoni Patj homolog 0.0009 0.0013 0.0016
Mycobacterium ulcerans hypothetical protein 0.0009 0.0005 0.0009
Loa Loa (eye worm) PDZ-domain-containing protein scribble 0.0009 0.0013 0.0015
Brugia malayi hypothetical protein 0.0009 0.0013 0.0015
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0165 0.0266
Echinococcus multilocularis exonuclease 1 0.0011 0.0032 0.0047
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0051 0.0077
Loa Loa (eye worm) PX domain-containing protein 0.0009 0.0013 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0032 0.0043
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0165 0.0257
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0009 0.0005 0.0005
Schistosoma mansoni dishevelled 0.0009 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0026 0.0246 0.0281
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0176 0.0176
Echinococcus granulosus partitioning defective 3 0.0009 0.0013 0.0016
Echinococcus granulosus bloom syndrome protein 0.0021 0.0176 0.0279
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Brugia malayi Cytochrome P450 family protein 0.0098 0.124 0.1414
Brugia malayi hypothetical protein 0.0018 0.0136 0.0155
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0352 0.4773 0.7688
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0009 0.0013 0.0016
Loa Loa (eye worm) XPG I-region family protein 0.0011 0.0032 0.0037
Loa Loa (eye worm) AGC/MAST/MAST protein kinase 0.0009 0.0013 0.0015
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.1478 0.2378
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0349 0.0399
Brugia malayi hypothetical protein 0.0009 0.0013 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0307 0.035
Echinococcus multilocularis glutamate receptor interacting protein 1 0.0009 0.0013 0.0016
Loa Loa (eye worm) WD domain-containing protein 0.0026 0.0246 0.0281
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0032 0.0032
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0158 0.0158
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0225 0.0256
Onchocerca volvulus 0.0009 0.0013 0.0013
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0053 0.0624 0.0997
Schistosoma mansoni PDZ domain protein 0.0009 0.0013 0.0016
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.1478 0.3517
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0009 0.0013 0.0016
Echinococcus granulosus pdz domain containing protein 0.0009 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0009 0.0005 0.0006
Schistosoma mansoni syntenin 0.0009 0.0013 0.0016
Echinococcus multilocularis dnaJ subfamily B 0.0407 0.5537 0.8919
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0009 0.0005 0.0005
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0349 0.1145
Schistosoma mansoni hypothetical protein 0.0009 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.002 0.0165 0.0188
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0009 0.0005 0.0013
Trichomonas vaginalis flap endonuclease-1, putative 0.0053 0.0624 0.0624
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0053 0.0624 0.0997
Loa Loa (eye worm) peripheral plasma membrane protein CASK 0.0009 0.0013 0.0015
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0165 0.0257
Loa Loa (eye worm) hypothetical protein 0.003 0.0303 0.0346
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.068 0.2245
Brugia malayi Cytochrome P450 family protein 0.0021 0.0178 0.0203
Echinococcus granulosus disks large 1 0.0009 0.0013 0.0016
Echinococcus granulosus histone lysine methyltransferase setb 0.0092 0.1164 0.1871
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0158 0.0175
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Loa Loa (eye worm) diaphorase 0.0052 0.06 0.0685
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.0178 0.0287
Echinococcus granulosus exonuclease 1 0.0011 0.0032 0.0047
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0009 0.0005 0.0009
Mycobacterium ulcerans monoxygenase 0.0009 0.0005 0.0009
Brugia malayi RasGEF domain containing protein 0.0009 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Brugia malayi syntenin 0.0009 0.0013 0.0015
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0009 0.0005 0.0004
Toxoplasma gondii melibiase subfamily protein 0.0108 0.1386 0.4584
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0013 0.0016
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0005 0.0005
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0009 0.0005 0.0007
Leishmania major nitrate reductase, putative 0.0052 0.06 0.096
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0003 0.0004
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0313 0.0499
Schistosoma mansoni alkaline phosphatase 0.0352 0.4773 0.7688
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0108 0.1386 0.2229
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0223 0.0352
Echinococcus granulosus geminin 0.0341 0.4623 0.7446
Treponema pallidum NADH oxidase 0.0034 0.0349 0.0394
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.0178 0.0287
Brugia malayi DIX domain containing protein 0.0009 0.0013 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.1164 0.1871
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0349 0.0553
Trypanosoma brucei NADH-dependent fumarate reductase 0.0052 0.06 0.096
Schistosoma mansoni hypothetical protein 0.0009 0.0013 0.0016
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0313 0.0813
Echinococcus multilocularis pdz domain containing protein 0.0009 0.0013 0.0016
Schistosoma mansoni hypothetical protein 0.0013 0.0058 0.0089
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.1478 0.2378
Schistosoma mansoni cytochrome P450 0.0021 0.0178 0.0282
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Schistosoma mansoni multiple pdz domain protein 0.0009 0.0013 0.0016
Leishmania major hypothetical protein, conserved 0.0011 0.0032 0.0043
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0158 0.0254
Loa Loa (eye worm) hypothetical protein 0.0455 0.6207 0.7077
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0349 0.0553
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0349 0.1145
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0027 0.0038
Schistosoma mansoni pdz domain containing protein 0.0009 0.0013 0.0016
Echinococcus multilocularis rho guanine nucleotide exchange factor 12 0.0009 0.0013 0.0016
Loa Loa (eye worm) cytochrome P450 0.0021 0.0178 0.0203
Schistosoma mansoni hypothetical protein 0.0009 0.0013 0.0016
Brugia malayi CXXC zinc finger family protein 0.0029 0.0278 0.0317
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0009 0.0013 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0165 0.0257
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0158 0.018
Echinococcus multilocularis Na(+):H(+) exchange regulatory cofactor NHE RF2 0.0009 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0003 0.00000000018384
Loa Loa (eye worm) guanylate kinase 0.0009 0.0013 0.0015
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0165 0.0257
Schistosoma mansoni multiple pdz domain protein 0.0009 0.0013 0.0016
Echinococcus multilocularis 0.0009 0.0013 0.0016
Toxoplasma gondii PUL domain-containing protein 0.0039 0.0423 0.1393
Brugia malayi hypothetical protein 0.0028 0.0275 0.0314
Schistosoma mansoni rab3 interacting molecule (rim)-related 0.0009 0.0013 0.0016
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0015 0.0093 0.0105
Echinococcus multilocularis dna polymerase eta 0.002 0.0165 0.0261
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0352 0.4773 0.7688
Brugia malayi hypothetical protein 0.0009 0.0013 0.0015
Echinococcus granulosus 55 kDa erythrocyte membrane protein 0.0009 0.0013 0.0016
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.1478 0.1689
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0165 0.0257
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0011 0.0032 0.0047
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0349 0.0553
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0349 0.0349
Brugia malayi glutathione reductase 0.0097 0.123 0.1402
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.0178 0.0287
Mycobacterium ulcerans glutamate synthase subunit beta 0.0009 0.0005 0.0009
Mycobacterium ulcerans ferredoxin reductase 0.0009 0.0005 0.0009
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0108 0.1386 0.2229
Plasmodium falciparum exonuclease I, putative 0.0011 0.0032 0.0047
Leishmania major oxidoreductase-like protein 0.0052 0.06 0.096
Loa Loa (eye worm) guanylate kinase 0.0009 0.0013 0.0015
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0192 0.0301
Schistosoma mansoni cell polarity protein 0.0009 0.0013 0.0016
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0158 0.0249
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0313 0.0358
Leishmania major cytochrome P450 reductase, putative 0.0403 0.5488 0.884
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0052 0.06 0.1574
Echinococcus granulosus cytochrome b5 reductase 4 0.0052 0.06 0.0963
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.0178 0.0424
Schistosoma mansoni hypothetical protein 0.0009 0.0013 0.0016
Echinococcus multilocularis pdz domain containing protein 0.0009 0.0013 0.0016
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0003 0.0004
Brugia malayi Flap endonuclease-1 0.0053 0.0624 0.0711
Onchocerca volvulus 0.0009 0.0013 0.0013
Brugia malayi 9ORF binding protein 1 0.0009 0.0013 0.0015
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0349 0.0562
Treponema pallidum ferredoxin-NADP(+) reductase subunit alpha 0.0052 0.06 0.0682
Schistosoma mansoni leucine-rich repeat protein 0.0009 0.0013 0.0016
Mycobacterium tuberculosis Probable monooxygenase 0.0052 0.06 0.1429
Plasmodium falciparum ferredoxin--NADP reductase 0.0052 0.06 0.0963
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0313 0.0352
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0052 0.06 0.096
Echinococcus multilocularis tight junction protein ZO 3 0.0009 0.0013 0.0016
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0176 0.0176
Echinococcus granulosus MAGUK p55 subfamily 0.0009 0.0013 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0165 0.0257
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0013 0.0016
Echinococcus granulosus tight junction protein ZO 3 0.0009 0.0013 0.0016
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.001 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0275 0.0436
Trypanosoma cruzi nitrate reductase, putative 0.0052 0.06 0.096
Schistosoma mansoni ran 0.0022 0.0192 0.0304
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0165 0.0392
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0311 0.4203 1
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0009 0.0005 0.0004
Brugia malayi PDZ-domain protein scribble 0.0009 0.0013 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0165 0.0257
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.1478 0.2378
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0221 0.2957 0.7033
Echinococcus granulosus protein lin 7 B 0.0009 0.0013 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0636 0.8728 0.8729
Mycobacterium tuberculosis Possible oxygenase 0.0052 0.06 0.1429
Schistosoma mansoni maguk P55 subfamily member 26 0.0009 0.0013 0.0016
Echinococcus granulosus nuclear factor of activated T cells 5 0.0078 0.0963 0.1547
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0092 0.1164 0.1871
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0052 0.06 0.0967
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0349 0.0553
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0313 0.1026
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0009 0.0013 0.0016
Echinococcus granulosus NADH cytochrome b5 reductase 3 0.0052 0.06 0.0963
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0011 0.0032 0.0047
Echinococcus granulosus death domain containing protein 0.0015 0.0093 0.0144
Brugia malayi Cytochrome P450 family protein 0.0031 0.0307 0.035
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0013 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.0178 0.0424
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0349 0.0553
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0165 0.0188
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0005 0.0005
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0009 0.0005 0.0006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0027 0.0038
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0108 0.1386 0.2229
Echinococcus multilocularis beta 1 syntrophin 0.0009 0.0013 0.0016
Onchocerca volvulus 0.0009 0.0013 0.0013
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0165 0.0261
Loa Loa (eye worm) syntrophin-1 0.0009 0.0013 0.0015
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0078 0.025
Echinococcus multilocularis phospholipase A 2 activating protein 0.0039 0.0423 0.0677
Schistosoma mansoni glutamate synthase 0.0009 0.0005 0.0004
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.0178 0.0424
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.0178 0.0287
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.1478 0.1478
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0051 0.0058
Onchocerca volvulus 0.0009 0.0013 0.0013
Loa Loa (eye worm) RecQ helicase 0.0021 0.0176 0.0201
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0455 0.6207 1
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.1478 0.1478
Brugia malayi Pre-SET motif family protein 0.0092 0.1164 0.1327
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Echinococcus multilocularis ligand of numb protein x 2 0.0009 0.0013 0.0016
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.0178 0.0287
Mycobacterium tuberculosis Probable reductase 0.0221 0.2957 0.7036
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0192 0.0304
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0009 0.0013 0.0016
Brugia malayi Partitioning defective-6 homolog alpha 0.0009 0.0013 0.0015
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0174 0.2301 0.2302
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0009 0.0013 0.0015
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.1478 0.1689
Brugia malayi Peripheral plasma membrane protein CASK 0.0009 0.0013 0.0015
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.0178 0.0287
Schistosoma mansoni pdz and lim domain protein 0.0009 0.0013 0.0016
Schistosoma mansoni regulator of G protein signaling 0.0009 0.0013 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0349 0.0553
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.1478 0.1689
Schistosoma mansoni hypothetical protein 0.0009 0.0013 0.0016
Schistosoma mansoni ap endonuclease 0.002 0.0158 0.0249
Trypanosoma cruzi reductase, putative 0.0052 0.06 0.096
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0108 0.1386 0.2229
Leishmania major cytochrome-b5 reductase, putative 0.0052 0.06 0.096
Schistosoma mansoni glutamate synthase 0.0009 0.0005 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0636 0.8728 0.8729
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0009 0.0005 0.0004
Echinococcus multilocularis neurabin 1 0.0009 0.0013 0.0016
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0005 0.0005
Echinococcus granulosus dna polymerase kappa 0.002 0.0165 0.0261
Leishmania major hypothetical protein, conserved 0.0174 0.2301 0.3702
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Schistosoma mansoni disulfide oxidoreductase 0.0009 0.0005 0.0004
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0032 0.0032
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0192 0.022
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0011
Giardia lamblia Fructose-bisphosphate aldolase 0.0636 0.8728 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0275 0.0439
Loa Loa (eye worm) hypothetical protein 0.0015 0.0094 0.0108
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0141 0.0221
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0158 0.0181
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0636 0.8728 1
Trypanosoma cruzi p450 reductase, putative 0.0052 0.06 0.096
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0349 0.0553
Echinococcus multilocularis snurportin 1 0.0324 0.4385 0.7063
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0174 0.2301 0.3704
Entamoeba histolytica type A flavoprotein, putative 0.0174 0.2301 0.2632
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0349 0.0553
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0246 0.33 0.7853
Plasmodium vivax hypothetical protein, conserved 0.0174 0.2301 0.3702
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0037
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0176 0.0279
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0349 0.0908
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0192 0.0301
Brugia malayi PX domain containing protein 0.0009 0.0013 0.0015
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0313 0.0313
Echinococcus multilocularis PRKCA binding protein 0.0009 0.0013 0.0016
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.0178 0.0424
Loa Loa (eye worm) hypothetical protein 0.0028 0.0275 0.0314
Echinococcus multilocularis methionine synthase reductase 0.0281 0.3788 0.61
Echinococcus multilocularis microtubule associated serine:threonine protein 0.0009 0.0013 0.0016
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.0027 0.0038
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0246 0.33 0.7853
Entamoeba histolytica hypothetical protein 0.0025 0.0235 0.0263
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0052 0.06 0.1429
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0303 0.048
Echinococcus granulosus pdz domain containing protein 0.0009 0.0013 0.0016
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0313 0.0352
Trichomonas vaginalis phospholipase A-2-activating protein, putative 0.0026 0.0246 0.0246
Brugia malayi flavodoxin family protein 0.0174 0.2301 0.2623
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0039 0.0054
Plasmodium vivax flavodoxin domain containing protein 0.0403 0.5488 0.884
Loa Loa (eye worm) cell junction protein LIN-7 0.0009 0.0013 0.0015
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0009 0.0005 0.0009
Echinococcus multilocularis glutamate synthase 0.0009 0.0005 0.0004
Schistosoma mansoni hypothetical protein 0.0183 0.2423 0.3901
Schistosoma mansoni cpg binding protein 0.003 0.0301 0.048
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.077 0.1237
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0009 0.0005 0.0013
Brugia malayi PDZ domain 0.0009 0.0013 0.0015
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0636 0.8728 1
Echinococcus multilocularis syndecan binding protein (syntenin) 0.0009 0.0013 0.0016
Schistosoma mansoni maguk P55 subfamily member 35 0.0009 0.0013 0.0016
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0313 0.0496
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0039 0.0054
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.0178 0.0424
Leishmania major trypanothione reductase 0.0097 0.123 0.1974
Echinococcus granulosus flap endonuclease 1 0.0053 0.0624 0.1001
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0158 0.4436
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0223 0.0223
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0093 0.0105
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.0178 0.0424
Onchocerca volvulus 0.0092 0.1164 0.1164
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0009 0.0005 0.0013
Plasmodium vivax thioredoxin reductase, putative 0.0097 0.123 0.1974
Schistosoma mansoni MAGUK homolog 0.0009 0.0013 0.0016
Giardia lamblia hypothetical protein 0.0011 0.0032 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0077 0.0115
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0455 0.6207 1
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0158 0.0158
Schistosoma mansoni ap endonuclease 0.002 0.0158 0.0249
Entamoeba histolytica type A flavoprotein, putative 0.0174 0.2301 0.2632
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0009 0.0005 0.0004
Schistosoma mansoni glutamate synthase 0.0009 0.0005 0.0004
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0009 0.0005 0.0013
Brugia malayi PDZ domain containing protein 0.0009 0.0013 0.0015
Leishmania major cytochrome-b5 reductase, putative 0.0052 0.06 0.096
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0009 0.0013 0.0016
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0005 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0165 0.0257
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0349 0.0557
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0092 0.1164 0.1871
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0349 0.0553
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0275 0.0436
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0039 0.0039
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0307 0.0486
Loa Loa (eye worm) cytochrome P450 family protein 0.0098 0.124 0.1414
Onchocerca volvulus Arc homolog 0.0009 0.0013 0.0013
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0313 0.0813
Plasmodium vivax flap endonuclease 1, putative 0.0053 0.0624 0.0997
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0039 0.0054
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0324 0.4385 0.5
Onchocerca volvulus 0.0009 0.0013 0.0013
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0349 0.0829
Giardia lamblia Glutamate synthase 0.0009 0.0005 0.0006
Trypanosoma brucei NADH-dependent fumarate reductase 0.0052 0.06 0.096
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0455 0.6207 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0246 0.33 0.785
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0303 0.048
Brugia malayi interleukin-16 0.0009 0.0013 0.0015
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0165 0.0261
Brugia malayi Syntrophin-1 0.0009 0.0013 0.0015
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0165 0.0257
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0009 0.0013 0.0016
Echinococcus multilocularis membrane associated guanylate kinase, WW and PDZ 0.0009 0.0013 0.0016
Brugia malayi Death domain containing protein 0.0015 0.0093 0.0105
Brugia malayi Cytochrome P450 family protein 0.0031 0.0307 0.035
Echinococcus granulosus membrane associated guanylate kinase, WW and PDZ 0.0009 0.0013 0.0016
Trichomonas vaginalis ran, putative 0.0022 0.0192 0.0192
Schistosoma mansoni sap-97 0.0009 0.0013 0.0016
Brugia malayi hypothetical protein 0.0009 0.0013 0.0015
Trypanosoma brucei exonuclease, putative 0.0011 0.0032 0.0043
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0349 0.0553
Plasmodium vivax importin-beta 2, putative 0.003 0.0303 0.048
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0455 0.6207 1
Leishmania major cytochrome p450-like protein 0.0031 0.0307 0.0486
Trypanosoma brucei unspecified product 0.0014 0.0077 0.0115
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0058 0.0089
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0165 0.0257
Brugia malayi FAD binding domain containing protein 0.0455 0.6207 0.7077
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0009 0.0005 0.0006
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0032 0.0097
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.0178 0.0282
Echinococcus multilocularis multiple pdz domain protein 0.0009 0.0013 0.0016
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0003 0.0004
Echinococcus granulosus beta 1 syntrophin 0.0009 0.0013 0.0016
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0221 0.2957 0.7036
Schistosoma mansoni NADPH flavin oxidoreductase 0.0229 0.3068 0.4941
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0349 0.0553
Brugia malayi Melibiase family protein 0.0072 0.0885 0.1009
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0077 0.0115
Loa Loa (eye worm) hypothetical protein 0.0015 0.0093 0.0105
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0303 0.0995
Echinococcus multilocularis protein piccolo 0.0009 0.0013 0.0016
Loa Loa (eye worm) RasGEF domain-containing protein 0.0009 0.0013 0.0015
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0349 0.0553
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.1164 0.1871
Schistosoma mansoni hypothetical protein 0.0021 0.0178 0.0282
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0093 0.0105
Echinococcus granulosus partitioning defective 3 0.0009 0.0013 0.0016
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0278 0.0317
Brugia malayi Neurabin protein 1 0.0009 0.0013 0.0015
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0108 0.1386 0.2229
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0307 0.0486
Brugia malayi PDZ domain containing protein 0.0009 0.0013 0.0015
Schistosoma mansoni cell polarity protein 0.0009 0.0013 0.0016
Brugia malayi cytochrome P450 0.0021 0.0178 0.0203
Leishmania major importin beta-1 subunit, putative 0.0025 0.0223 0.0352
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0636 0.8728 0.8729
Echinococcus granulosus syndecan binding protein syntenin 0.0009 0.0013 0.0016
Onchocerca volvulus 0.0009 0.0013 0.0013
Echinococcus granulosus Ankyrin 0.0015 0.0094 0.0147
Trypanosoma brucei trypanothione reductase 0.0097 0.123 0.1974
Brugia malayi PDZ domain 0.0009 0.0013 0.0015
Schistosoma mansoni hypothetical protein 0.0013 0.0058 0.0089
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0009 0.0005 0.0004
Leishmania major p450 reductase, putative 0.0455 0.6207 1
Schistosoma mansoni amyloid beta A4 protein related 0.0009 0.0013 0.0016
Loa Loa (eye worm) gopc protein 0.0009 0.0013 0.0015
Echinococcus multilocularis MAGUK p55 subfamily 0.0009 0.0013 0.0016
Echinococcus multilocularis glutamate receptor interacting protein 1 0.0009 0.0013 0.0016
Schistosoma mansoni hypothetical protein 0.0015 0.0093 0.0144
Brugia malayi microtubule-associated serine/threonine protein kinase 2 (MAST2) 0.0009 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Echinococcus granulosus glutamate receptor interacting protein 1 0.0009 0.0013 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0313 0.0313
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.0178 0.0424
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.1478 0.1685
Brugia malayi Patj homolog 0.0009 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Leishmania major cytochrome p450-like protein 0.0021 0.0178 0.0279
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0009 0.0013 0.0016
Echinococcus multilocularis disks large 1 0.0009 0.0013 0.0016
Echinococcus granulosus Partitioning defective 3 protein B 0.0009 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Mycobacterium leprae Conserved hypothetical protein 0.0021 0.0178 0.0412
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0052 0.06 0.096
Schistosoma mansoni hypothetical protein 0.0009 0.0013 0.0016
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0455 0.6207 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0639 0.8771 1
Treponema pallidum flavodoxin 0.0174 0.2301 0.2632
Toxoplasma gondii Alpha-galactosidase 0.0015 0.0094 0.0302
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0009 0.0005 0.0004
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.0178 0.0287
Schistosoma mansoni flap endonuclease-1 0.0048 0.0553 0.0886
Echinococcus granulosus MAGUK p55 subfamily 0.0009 0.0013 0.0016
Onchocerca volvulus 0.0009 0.0013 0.0013
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0313 0.0313
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0011 0.0032 0.0043
Loa Loa (eye worm) PDZ domain-containing protein 0.0009 0.0013 0.0015
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0174 0.2301 0.3702
Schistosoma mansoni dishevelled 0.0009 0.0013 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0636 0.8728 0.8729
Echinococcus granulosus Rho GTPase activating protein 21 0.0009 0.0013 0.0016
Schistosoma mansoni sh3 and multiple ankyrin repeat domains protein 12 (shank12) 0.001 0.0015 0.0019
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0009 0.0005 0.0013
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0174 0.2301 0.2302
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.0003 0.0004
Giardia lamblia Exonuclease 1 0.0011 0.0032 0.0037
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0052 0.06 0.096
Loa Loa (eye worm) phosphofructokinase 0.0115 0.1478 0.1685
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0165 0.0261
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0005 0.0005
Giardia lamblia Hypothetical protein 0.0403 0.5488 0.6288
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0032 0.0032
Leishmania major NADH-dependent fumarate reductase-like protein 0.0052 0.06 0.096
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Echinococcus granulosus disks large 3 0.0009 0.0013 0.0016
Echinococcus multilocularis Partitioning defective 3 protein B 0.0009 0.0013 0.0016
Schistosoma mansoni discs lost-related 0.0009 0.0013 0.0016
Echinococcus granulosus rho guanine nucleotide exchange factor 12 0.0009 0.0013 0.0016
Echinococcus granulosus glutamate synthase 0.0009 0.0005 0.0004
Leishmania major cytochrome p450-like protein 0.0021 0.0178 0.0279
Leishmania major hypothetical protein, conserved 0.0039 0.0423 0.0674
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.0178 0.0424
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0009 0.0005 0.0007
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0072 0.0885 0.1421
Mycobacterium ulcerans dehydrogenase 0.0009 0.0005 0.0009
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0165 0.0257
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0013 0.0016
Echinococcus multilocularis protein lin 7 B 0.0009 0.0013 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.0178 0.0424
Echinococcus multilocularis multiple pdz domain protein 0.0009 0.0013 0.0016
Trichomonas vaginalis apoptosis inducing factor, putative 0.0009 0.0005 0.0005
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.1478 0.1689
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0032 0.0097
Entamoeba histolytica Flap nuclease, putative 0.0053 0.0624 0.0709
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0158 0.0175
Leishmania major reductase, putative 0.0052 0.06 0.096
Brugia malayi gamma-syntrophin-like protein SYN2 0.0009 0.0013 0.0015
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0165 0.0257
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0072 0.0885 0.0885
Loa Loa (eye worm) X11 protein 0.0009 0.0013 0.0015
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.1478 0.2375
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0009 0.0005 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.0178 0.0424
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.0178 0.0424
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Mycobacterium tuberculosis Probable oxidoreductase 0.0052 0.06 0.1429
Plasmodium falciparum glutathione reductase 0.0034 0.0349 0.0557
Schistosoma mansoni multiple pdz domain protein 0.0009 0.0013 0.0016
Brugia malayi Pre-SET motif family protein 0.0639 0.8771 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0275 0.0436
Brugia malayi Synapse defective protein 1 0.0009 0.0013 0.0015
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0009 0.0005 0.0009
Echinococcus granulosus multiple pdz domain protein 0.0009 0.0013 0.0016
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0108 0.1386 0.2229
Echinococcus granulosus cell polarity protein 0.0009 0.0013 0.0016
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0158 0.0245
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0158 0.0245
Toxoplasma gondii NADH-cytochrome b5 reductase 1, putative 0.0052 0.06 0.198
Schistosoma mansoni leucine-rich repeat protein 0.0009 0.0013 0.0016
Schistosoma mansoni hypothetical protein 0.0009 0.0013 0.0016
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0165 0.0188
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0223 0.0223
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0349 1
Giardia lamblia Flavohemoprotein lateral transfer candidate 0.0052 0.06 0.0688
Brugia malayi RNA, U transporter 1 0.0086 0.1081 0.1233
Echinococcus granulosus dnaJ subfamily B 0.0407 0.5537 0.8919
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0052 0.06 0.096
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0032 0.0097
Plasmodium falciparum ferrodoxin reductase-like protein 0.0009 0.0005 0.0004
Echinococcus granulosus MAGUK p55 subfamily 0.0009 0.0013 0.0016
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.0178 0.0287
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0009 0.0005 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0636 0.8728 0.8729
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0052 0.06 0.096
Trichomonas vaginalis phospholipase A-2-activating protein, putative 0.0039 0.0423 0.0423
Brugia malayi PDZ domain containing protein 0.0009 0.0013 0.0015
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.0178 0.058
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0165 0.0257
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.1478 0.1478
Toxoplasma gondii thioredoxin reductase 0.0097 0.123 0.4066
Plasmodium falciparum flap endonuclease 1 0.0053 0.0624 0.1001
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0092 0.1164 0.1871
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0158 0.0245
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0011 0.0032 0.0047
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0005 0.0005
Loa Loa (eye worm) flap endonuclease-1 0.0053 0.0624 0.0711
Brugia malayi Importin beta-1 subunit 0.003 0.0303 0.0346
Echinococcus multilocularis alkaline phosphatase 0.0352 0.4773 0.7688
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0165 0.0165
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0093 0.0144
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0097 0.123 0.2926
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0636 0.8728 0.8729
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0009 0.0013 0.0016
Leishmania major GTP-binding protein, putative 0.0022 0.0192 0.0301
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0192 0.0625
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.0178 0.0287
Schistosoma mansoni hypothetical protein 0.0407 0.5537 0.8919
Echinococcus granulosus Microtubule-associated serine/threonine-protein kinase 0.0009 0.0013 0.0016
Schistosoma mansoni discs large 0.0009 0.0013 0.0016
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0455 0.6207 1
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0174 0.2301 0.2302
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.0178 0.0287
Brugia malayi Ferm domain 0.0009 0.0013 0.0015
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0009 0.0005 0.0007
Leishmania major NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0009 0.0005 0.0013
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0176 0.0201
Onchocerca volvulus 0.0009 0.0013 0.0013
Echinococcus multilocularis flap endonuclease GEN 1 0.0011 0.0032 0.0047
Schistosoma mansoni lin-7-like proteins 0.0009 0.0013 0.0016
Echinococcus multilocularis partitioning defective 3 0.0009 0.0013 0.0016
Schistosoma mansoni cell polarity protein 0.0009 0.0013 0.0016
Brugia malayi diaphorase 0.0052 0.06 0.0685
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0009 0.0013 0.0016
Echinococcus granulosus myeloid:lymphoid or mixed lineage leukemia 0.0009 0.0013 0.0016
Brugia malayi Uncoordinated protein 44 0.0015 0.0093 0.0105
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0165 0.0257
Echinococcus multilocularis cytochrome b5 reductase 4 0.0052 0.06 0.0963
Schistosoma mansoni hypothetical protein 0.0009 0.0005 0.0004
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0455 0.6207 1
Trypanosoma brucei DNA repair protein RAD2, putative 0.0011 0.0032 0.0043
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0158 0.0249
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0349 0.0397
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.0178 0.0287
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0009 0.0013 0.0016
Echinococcus granulosus dna polymerase eta 0.002 0.0165 0.0261
Trypanosoma cruzi WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0039 0.0423 0.0674
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0158 0.018
Brugia malayi WD domain containing protein 0.0039 0.0423 0.0483
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0275 0.0436
Trichomonas vaginalis glutamate synthase, putative 0.0009 0.0005 0.0005
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0072 0.0885 0.1421
Trichomonas vaginalis glutamate synthase, putative 0.0009 0.0005 0.0005
Trypanosoma brucei unspecified product 0.002 0.0165 0.0257
Brugia malayi phosphofructokinase 0.0115 0.1478 0.1685
Schistosoma mansoni cell polarity protein 0.0009 0.0013 0.0016
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.0178 0.0279
Echinococcus multilocularis Ankyrin 0.0015 0.0094 0.0147
Loa Loa (eye worm) DIX domain-containing protein 0.0009 0.0013 0.0015
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0158 0.0375
Schistosoma mansoni protein kinase C alpha binding protein 0.0009 0.0013 0.0016
Entamoeba histolytica exonuclease, putative 0.0011 0.0032 0.0031
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0165 0.0165
Giardia lamblia DINP protein human, muc B family 0.002 0.0165 0.0189
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0009 0.0005 0.0004
Onchocerca volvulus 0.0029 0.0278 0.0278
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0192 0.0301
Schistosoma mansoni netrin receptor unc5 0.0015 0.0093 0.0144
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0009 0.0005 0.0004
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.0027 0.0038
Echinococcus multilocularis pdz domain containing protein 0.0009 0.0013 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0313 0.0313
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0165 0.0257
Loa Loa (eye worm) 9ORF binding protein 1 0.0009 0.0013 0.0015
Echinococcus multilocularis cell polarity protein leucine rich repeat 0.0009 0.0013 0.0016
Schistosoma mansoni hypothetical protein 0.0009 0.0013 0.0016
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0049 0.0056
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.0178 0.0424
Plasmodium vivax exonuclease I, putative 0.0011 0.0032 0.0043
Echinococcus multilocularis disks large 3 0.0009 0.0013 0.0016
Schistosoma mansoni ran 0.0022 0.0192 0.0304
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.1164 0.1871
Echinococcus multilocularis thioredoxin glutathione reductase 0.0097 0.123 0.1977
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0013 0.0015
Trypanosoma cruzi p450 reductase, putative 0.0455 0.6207 1
Echinococcus multilocularis partitioning defective protein 6 0.0009 0.0013 0.0016
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0032 0.0032
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.0178 0.0287
Echinococcus granulosus multiple pdz domain protein 0.0009 0.0013 0.0016
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0081 0.0122
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0052 0.06 0.096
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0313 0.1026
Schistosoma mansoni hypothetical protein 0.0324 0.4385 0.7063
Brugia malayi gopc protein 0.0009 0.0013 0.0015
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0052 0.06 0.096
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0009 0.0013 0.0013
Schistosoma mansoni diflavin oxidoreductase 0.0226 0.302 0.4863
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0223 0.0223
Entamoeba histolytica hypothetical protein 0.0025 0.0223 0.025
Brugia malayi protein kinase C-binding protein PICK1 0.0009 0.0013 0.0015
Trypanosoma brucei WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0026 0.0246 0.0389
Echinococcus granulosus intestinal type alkaline phosphatase 0.0352 0.4773 0.7688
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0037
Loa Loa (eye worm) PAR-6 protein 0.0009 0.0013 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.0178 0.0424
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0009 0.0013 0.0016
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0015 0.0094 0.0147
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0313 0.0313
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0275 0.0439
Entamoeba histolytica DNA-repair protein, putative 0.0011 0.0032 0.0031
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.0178 0.0424
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0009 0.0005 0.0006
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0009 0.0005 0.0004
Schistosoma mansoni cytochrome B5 0.0052 0.06 0.0963
Brugia malayi 6-phosphofructokinase 0.0115 0.1478 0.1685
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.0178 0.0287
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Brugia malayi follicle stimulating hormone receptor 0.0478 0.6521 0.7435
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.0178 0.0279
Plasmodium vivax SET domain protein, putative 0.0092 0.1164 0.1868
Echinococcus multilocularis Rho GTPase activating protein 21 0.0009 0.0013 0.0016
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0455 0.6207 1
Schistosoma mansoni DNA polymerase eta 0.002 0.0165 0.0261
Brugia malayi cell junction protein LIN-7 0.0009 0.0013 0.0015
Brugia malayi Protein-tyrosine phosphatase 1 0.0009 0.0013 0.0015
Trichomonas vaginalis set domain proteins, putative 0.0728 0.9998 1
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0011 0.0032 0.0043
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0039 0.0039
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0027 0.0038
Echinococcus granulosus phospholipase A 2 activating protein 0.0039 0.0423 0.0677
Entamoeba histolytica exonuclease, putative 0.0011 0.0032 0.0031
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0052 0.06 0.096
Loa Loa (eye worm) FAD binding domain-containing protein 0.0455 0.6207 0.7077
Echinococcus multilocularis PDZ domain containing protein GIPC3 0.0009 0.0013 0.0016
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0009 0.0013 0.0016
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.0178 0.0424
Mycobacterium leprae putative cytochrome p450 0.0021 0.0178 0.0412
Mycobacterium ulcerans monooxygenase 0.0052 0.06 0.0967
Echinococcus multilocularis cpg binding protein 0.003 0.0301 0.048
Echinococcus multilocularis NADH cytochrome b5 reductase 3 0.0052 0.06 0.0963
Schistosoma mansoni pdz domain containing protein 0.0009 0.0013 0.0016
Echinococcus granulosus methionine synthase reductase 0.0281 0.3788 0.61
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0311 0.4203 0.6771
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.1478 0.1685
Schistosoma mansoni multiple pdz domain protein 0.0009 0.0013 0.0016
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0009 0.0013 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.0178 0.0424
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0051 0.0077
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.0178 0.0287
Plasmodium falciparum NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.0963
Leishmania major NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Onchocerca volvulus 0.0009 0.0013 0.0013
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.0178 0.0287
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.1478 0.2375
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0165 0.0257
Brugia malayi flavodoxin family protein 0.0455 0.6207 0.7077
Giardia lamblia Thioredoxin reductase 0.0009 0.0005 0.0006
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0455 0.6207 1
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.0178 0.0424
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Echinococcus granulosus pdz domain containing protein 0.0009 0.0013 0.0016
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0009 0.0005 0.0005
Brugia malayi Abnormal embryonic partitioning of cytoplasm protein 3 0.0009 0.0013 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.0178 0.0424
Plasmodium falciparum thioredoxin reductase 0.0034 0.0349 0.0557
Echinococcus multilocularis dna polymerase kappa 0.002 0.0165 0.0261
Schistosoma mansoni cpg binding protein 0.003 0.0301 0.048
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0108 0.1386 0.2229
Echinococcus multilocularis multiple pdz domain protein 0.0009 0.0013 0.0016
Trypanosoma brucei nitrate reductase, putative 0.0052 0.06 0.096
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0009 0.0005 0.0006
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0093 0.0144
Echinococcus granulosus snurportin 1 0.0324 0.4385 0.7063
Schistosoma mansoni syntrophin 0.0009 0.0013 0.0016
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0094 0.0147
Brugia malayi hypothetical protein 0.0009 0.0013 0.0015
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0455 0.6207 1
Toxoplasma gondii flavodoxin domain-containing protein 0.0226 0.302 1
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0009 0.0005 0.0004
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Schistosoma mansoni MAGUK homolog 0.0009 0.0013 0.0016
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0349 0.0557
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0349 0.0553
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0313 0.1026
Echinococcus multilocularis flap endonuclease 1 0.0053 0.0624 0.1001
Plasmodium vivax glutathione reductase, putative 0.0097 0.123 0.1974
Trypanosoma brucei oxidoreductase-protein, putative 0.0052 0.06 0.096
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0058 0.0089
Loa Loa (eye worm) hypothetical protein 0.0017 0.0117 0.0133
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0009 0.0013 0.0016
Echinococcus multilocularis 55 kDa erythrocyte membrane protein 0.0009 0.0013 0.0016
Brugia malayi Cytochrome b5-like Heme/Steroid binding domain containing protein 0.0052 0.06 0.0685
Onchocerca volvulus 0.0009 0.0005 0.0005
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0032 0.0097
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0349 0.0553
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0352 0.4773 0.7688
Echinococcus granulosus cytochrome b5 reductase 4 0.0052 0.06 0.0963
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0092 0.1164 0.3847
Leishmania major DNA polymerase eta, putative 0.002 0.0165 0.0257
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0052 0.06 0.1429
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.0178 0.0279
Echinococcus multilocularis membrane associated guanylate kinase ww and pdz 0.0009 0.0013 0.0016
Giardia lamblia Flap structure-specific endonuclease 0.0053 0.0624 0.0715
Trypanosoma brucei unspecified product 0.0014 0.0077 0.0115
Mycobacterium ulcerans oxygenase 0.0052 0.06 0.0967
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0455 0.6207 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0349 0.0553
Trypanosoma cruzi WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0039 0.0423 0.0674
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0349 1
Schistosoma mansoni hypothetical protein 0.0341 0.4623 0.7446
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0307 0.035
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0009 0.0013 0.0016
Brugia malayi Guanylate kinase family protein 0.0009 0.0013 0.0015
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0174 0.2301 0.2302
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0178 0.0279
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0349 0.0557
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0636 0.8728 0.8729
Giardia lamblia Nitric oxide synthase, inducible 0.0403 0.5488 0.6288
Schistosoma mansoni NADH-cytochrome B5 reductase 0.0052 0.06 0.0963
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0031 0.0307 0.0494
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Brugia malayi Hypothetical 13.5 kDa protein C45G9.7 in chromosome III 0.0009 0.0013 0.0015
Plasmodium falciparum glutathione reductase 0.0097 0.123 0.1977
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0352 0.4773 0.7688
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0174 0.2301 0.3702
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0009 0.0013 0.0015
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0158 0.0245
Trypanosoma brucei cytochrome P450, putative 0.0031 0.0307 0.0486
Echinococcus granulosus thioredoxin glutathione reductase 0.0097 0.123 0.1977
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Leishmania major NADH-dependent fumarate reductase, putative 0.0052 0.06 0.096
Echinococcus multilocularis amyloid beta A4 protein 0.0009 0.0013 0.0016
Trichomonas vaginalis exonuclease%2C+putative 0.0011 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0072 0.0885 0.1009
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0221 0.2957 0.7036
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0349 0.0562
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.0178 0.0287
Echinococcus multilocularis pdz domain containing protein 0.0009 0.0013 0.0016
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0174 0.2301 0.3702
Echinococcus granulosus alkaline phosphatase 0.0352 0.4773 0.7688
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0349 0.0553
Echinococcus granulosus Na:H exchange regulatory cofactor NHE RF2 0.0009 0.0013 0.0016
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0349 0.0553
Onchocerca volvulus 0.0009 0.0013 0.0013
Schistosoma mansoni ATP-dependent RNA Helicase 0.0009 0.0013 0.0016
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Echinococcus multilocularis 0.0021 0.0178 0.0282
Entamoeba histolytica Ran family GTPase 0.0022 0.0192 0.0214
Brugia malayi rho guanine nucleotide exchange factor 12 0.0009 0.0013 0.0015
Echinococcus granulosus importin subunit beta 1 0.003 0.0303 0.0484
Loa Loa (eye worm) FAD binding domain-containing protein 0.0281 0.3788 0.4318
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0313 0.0496
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0158 0.0249
Schistosoma mansoni phospholipase A-2-activating protein 0.0026 0.0246 0.0392
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0478 0.6521 0.7435
Schistosoma mansoni hypothetical protein 0.0009 0.0013 0.0016
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0158 0.0245
Plasmodium vivax oxidoreductase NAD-binding domain containing protein 0.0052 0.06 0.096
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0009 0.0005 0.0004
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0225 0.0256
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0165 0.0257
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0349 0.0557
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0093 0.0144
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0192 0.0304
Echinococcus granulosus 3'partial|membrane associated guanylate kinase ww and pdz 0.0009 0.0013 0.0016
Echinococcus multilocularis myeloid:lymphoid or mixed lineage leukemia 0.0009 0.0013 0.0016
Toxoplasma gondii ferredoxin NADP+ oxidoreductase FNR 0.0052 0.06 0.198
Schistosoma mansoni hypothetical protein 0.0009 0.0013 0.0016
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0192 0.0219
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0015
Trypanosoma cruzi oxidoreductase-protein, putative 0.0052 0.06 0.096
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0009 0.0013 0.0016
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.0178 0.0287
Echinococcus multilocularis MAGUK p55 subfamily 0.0009 0.0013 0.0016
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0114 0.0179
Schistosoma mansoni tight junction protein 0.0009 0.0013 0.0016
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0052 0.06 0.096
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0221 0.2957 0.7036
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0009 0.0013 0.0016
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.0178 0.0287
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0313 0.0313
Schistosoma mansoni hypothetical protein 0.0009 0.0013 0.0016
Brugia malayi FAD binding domain containing protein 0.0281 0.3788 0.4318
Brugia malayi Guanylate kinase family protein 0.0009 0.0013 0.0015
Plasmodium falciparum polyubiquitin binding protein, putative 0.0039 0.0423 0.0677
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0052 0.06 0.0967
Brugia malayi hypothetical protein 0.0009 0.0013 0.0015
Mycobacterium tuberculosis Probable dehydrogenase 0.0221 0.2957 0.7036
Echinococcus granulosus cpg binding protein 0.003 0.0301 0.048
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0009 0.0013 0.0016
Onchocerca volvulus 0.0052 0.06 0.06
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0192 0.0304
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0455 0.6207 1
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0009 0.0005 0.0009
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0221 0.2957 0.7036
Schistosoma mansoni exonuclease 0.0011 0.0032 0.0047
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0009 0.0005 0.0009
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0088 0.1108 0.1781
Mycobacterium ulcerans oxidoreductase 0.0052 0.06 0.0967
Toxoplasma gondii selenide, water dikinase 0.0009 0.0005 0.0007
Echinococcus granulosus neurabin 1 0.0009 0.0013 0.0016
Echinococcus multilocularis partitioning defective 3 0.0009 0.0013 0.0016
Echinococcus granulosus PRKCA binding protein 0.0009 0.0013 0.0016
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0281 0.3788 0.61
Trypanosoma brucei NADH-cytochrome b5 reductase-like protein 0.0052 0.06 0.096
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0009 0.0005 0.0004

Activities

Activity type Activity value Assay description Source Reference
ED2 (functional) > 4000 ug kg-1 In vivo activity using McPhail test after oral dose ChEMBL. No reference
RBA (binding) = 1 Relative binding affinity (RBA) to progesterone receptor of MCF-7 cytosol ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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