Detailed information for compound 176022

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 301.319 | Formula: C11H15N3O5S
  • H donors: 4 H acceptors: 5 LogP: -1.65 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1NC(=O)C)O)c1scc(n1)C(=O)N
  • InChi: 1S/C11H15N3O5S/c1-4(16)13-7-6(2-15)19-9(8(7)17)11-14-5(3-20-11)10(12)18/h3,6-9,15,17H,2H2,1H3,(H2,12,18)(H,13,16)/t6-,7-,8-,9-/m1/s1
  • InChiKey: FJUCDRWGPMQXKK-FNCVBFRFSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Toxoplasma gondii histone lysine methyltransferase SET1 0.0037 0.0074 0.0074
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0158 0.0158
Schistosoma mansoni BC026374 protein (S09 family) 0.0029 0.0051 0.005
Echinococcus granulosus 7TM GPCR rhodopsin 0.0218 0.0592 0.0592
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0111 0.0286 0.036
Brugia malayi hypothetical protein 0.0218 0.0592 0.0747
Schistosoma mansoni hypothetical protein 0.0063 0.0147 0.0146
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0038 0.0038
Trypanosoma brucei unspecified product 0.0019 0.0022 0.0027
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0158 0.0199
Loa Loa (eye worm) hypothetical protein 0.0062 0.0146 0.0183
Echinococcus granulosus g-protein coupled receptor 0.0218 0.0592 0.0592
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0952 0.2691 0.2691
Schistosoma mansoni hypothetical protein 0.0063 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Brugia malayi hypothetical protein 0.0123 0.0321 0.0404
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0012 0.0003 0.0003
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.005 0.0111 0.0111
Echinococcus multilocularis neuroligin 0.0029 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.022 0.0597 0.0753
Schistosoma mansoni tyrosine kinase 0.0083 0.0206 0.0206
Loa Loa (eye worm) CYP4Cod1 0.014 0.0369 0.0465
Echinococcus granulosus Chromobox protein 3 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Echinococcus multilocularis importin subunit beta 1 0.0043 0.0091 0.009
Trichomonas vaginalis penicillin-binding protein, putative 0.0085 0.0211 0.1882
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.022 0.0597 0.0753
Echinococcus granulosus neural cadherin 0.0063 0.0147 0.0146
Echinococcus granulosus biogenic amine 5HT receptor 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0001 0.0001
Brugia malayi Sodium Bile acid symporter family protein 0.012 0.0311 0.0393
Schistosoma mansoni hypothetical protein 0.0075 0.0182 0.0181
Loa Loa (eye worm) histone deacetylase 0.0018 0.002 0.0024
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0035 0.0068 0.0086
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0218 0.0592 0.1611
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0013 0.008
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0218 0.0592 0.0592
Echinococcus multilocularis peroxidasin 0.0463 0.1293 0.1293
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0012 0.0002 0.0026
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0094 0.0255
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0017 0.0015 0.0018
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0082 0.0203 0.474
Echinococcus multilocularis voltage gated potassium channel 0.0017 0.0015 0.0015
Schistosoma mansoni transient receptor potential channel 0.0043 0.009 0.0089
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0069 0.0612
Echinococcus multilocularis hormone sensitive lipase 0.022 0.0598 0.0597
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0027 0.0233
Onchocerca volvulus 0.0063 0.0147 0.0399
Brugia malayi Cytochrome P450 family protein 0.014 0.0369 0.0465
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0017 0.0018 0.0022
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.013 0.0163
Loa Loa (eye worm) beta-lactamase 0.0085 0.0211 0.0266
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0002 0.0026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0013 0.0114
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0002 0.0053
Echinococcus multilocularis neurogenic locus notch protein 4 0.0063 0.0147 0.0146
Echinococcus multilocularis serotonin receptor 0.0218 0.0592 0.0592
Echinococcus granulosus Solute carrier family 22 5 0.2174 0.6191 0.6191
Mycobacterium leprae Conserved hypothetical protein 0.0082 0.0203 0.6872
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0082 0.0203 0.1329
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0076 0.0075
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.002 0.0024
Echinococcus multilocularis fmrfamide receptor 0.0218 0.0592 0.0592
Echinococcus multilocularis neuropeptides capa receptor 0.0218 0.0592 0.0592
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0218 0.0592 0.0592
Brugia malayi Cyclic-nucleotide gated cation channel 0.0013 0.0006 0.0007
Echinococcus multilocularis Chromo domain 0.0012 0.0002 0.0002
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0015 0.0097
Schistosoma mansoni zinc finger protein 0.0022 0.003 0.0029
Onchocerca volvulus 0.0085 0.0211 0.0573
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0035 0.0068 0.0445
Toxoplasma gondii hypothetical protein 0.0038 0.0076 0.0076
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0031 0.0707
Mycobacterium tuberculosis Conserved hypothetical protein 0.0027 0.0046 0.03
Brugia malayi Protein cec-1. 0.0012 0.0002 0.0002
Onchocerca volvulus 0.022 0.0597 0.1624
Echinococcus multilocularis 0.0082 0.0203 0.0202
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0027 0.0026
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0017 0.0018 0.0384
Entamoeba histolytica hypothetical protein 0.0075 0.0181 0.6143
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0035 0.0068 0.0067
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0027 0.0233
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0082 0.0203 0.1329
Leishmania major hypothetical protein, conserved 0.0085 0.0211 0.0266
Echinococcus granulosus sodium bile acid cotransporter 0.012 0.0311 0.0311
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.022 0.0597 0.0753
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0135 0.017
Brugia malayi Tachykinin-like peptides receptor 99D 0.0218 0.0592 0.0747
Onchocerca volvulus 0.022 0.0597 0.1624
Brugia malayi EGF-like domain containing protein 0.0063 0.0147 0.0185
Echinococcus multilocularis chromobox protein 2 0.0012 0.0002 0.0002
Echinococcus multilocularis lipoxygenase domain containing protein 0.0082 0.0201 0.0201
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0027 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0218 0.0592 0.0592
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0016 0.0014 0.0014
Entamoeba histolytica hypothetical protein 0.0021 0.0027 0.0886
Brugia malayi latrophilin 2 splice variant baaae 0.0162 0.0431 0.0543
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0019
Plasmodium vivax heterochromatin protein 1, putative 0.0012 0.0002 0.0029
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0056 0.0702
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0084 0.0209 0.0208
Brugia malayi neuropeptide F receptor 0.0218 0.0592 0.0747
Echinococcus granulosus tm gpcr rhodopsin 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Echinococcus multilocularis carboxylesterase 5A 0.0171 0.0458 0.0457
Schistosoma mansoni cpg binding protein 0.0017 0.0017 0.0017
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0082 0.0203 0.1329
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Echinococcus granulosus Chromo domain 0.0012 0.0002 0.0002
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0082 0.0203 0.1329
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0052
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Echinococcus multilocularis neurogenic locus notch protein 0.0063 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0022 0.0031 0.0202
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Brugia malayi GCC2 and GCC3 family protein 0.0063 0.0147 0.0185
Entamoeba histolytica hypothetical protein 0.0012 0.0002 0.0053
Loa Loa (eye worm) latrophilin receptor protein 2 0.0075 0.0182 0.0229
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0082 0.0203 0.474
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.013 0.1156
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0027 0.0026
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0082 0.0203 0.474
Schistosoma mansoni hypothetical protein 0.0162 0.0431 0.043
Schistosoma mansoni z-protein (S1r protein) 0.0026 0.0042 0.0041
Schistosoma mansoni neuropeptide F-like receptor 0.0218 0.0592 0.0592
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0235 0.0639 0.0807
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0002 0.0002
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0171 0.0458 0.0457
Echinococcus granulosus GTP binding nuclear protein Ran 0.0032 0.0058 0.0058
Loa Loa (eye worm) RecQ helicase 0.0017 0.0016 0.0019
Schistosoma mansoni transcription factor LCR-F1 0.0075 0.0181 0.0181
Echinococcus multilocularis protein jagged 2 0.0063 0.0147 0.0146
Loa Loa (eye worm) MH2 domain-containing protein 0.0072 0.0173 0.0218
Brugia malayi glutaminase DH11.1 0.016 0.0427 0.0538
Trypanosoma brucei histone deacetylase 4 0.0018 0.002 0.0024
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0056 0.1889
Brugia malayi putative neuropeptide receptor 0.0218 0.0592 0.0747
Brugia malayi Cytochrome P450 family protein 0.0082 0.0203 0.0256
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0085 0.0211 0.4936
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0218 0.0592 0.0747
Echinococcus multilocularis notch 0.0063 0.0147 0.0146
Loa Loa (eye worm) isocitrate dehydrogenase 0.0022 0.0029 0.0037
Echinococcus multilocularis zinc finger protein 0.0022 0.003 0.0029
Schistosoma mansoni amine GPCR 0.0577 0.1619 0.1619
Onchocerca volvulus Peroxidasin homolog 0.0463 0.1293 0.352
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0033
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0032 0.0058 0.0971
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.0295 1
Schistosoma mansoni slit 0.0063 0.0147 0.0146
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0023 0.0033 0.0041
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.022 0.0597 0.0596
Schistosoma mansoni lipoxygenase 0.0488 0.1363 0.1363
Onchocerca volvulus 0.0023 0.0033 0.0088
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Plasmodium falciparum amino acid transporter, putative 0.022 0.0597 1
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0013 0.0006 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0082 0.0203 0.1329
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.022 0.0597 0.0596
Schistosoma mansoni amine GPCR 0.0218 0.0592 0.0592
Schistosoma mansoni ran 0.0032 0.0058 0.0058
Onchocerca volvulus 0.0218 0.0592 0.1611
Brugia malayi cytoplasmic intermediate filament protein 0.0035 0.0067 0.0084
Echinococcus granulosus expressed protein 0.04 0.1112 0.1112
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Echinococcus granulosus sex peptide receptor 0.0218 0.0592 0.0592
Entamoeba histolytica hypothetical protein 0.0021 0.0027 0.0886
Loa Loa (eye worm) neuropeptide F receptor 0.0218 0.0592 0.0747
Echinococcus multilocularis sodium bile acid cotransporter 0.012 0.0311 0.0311
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0012 0.0001 0.0005
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0019 0.0019
Echinococcus multilocularis bloom syndrome protein 0.0017 0.0016 0.0015
Onchocerca volvulus 0.0063 0.0147 0.0399
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0135 0.017
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.004 0.0083 0.0104
Brugia malayi polk-prov protein 0.004 0.0081 0.0102
Echinococcus multilocularis neuropeptide s receptor 0.0218 0.0592 0.0592
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0135 0.017
Echinococcus granulosus chromobox protein 1 0.0073 0.0177 0.0177
Echinococcus granulosus fatty acid binding protein FABP2 0.0036 0.0072 0.0071
Echinococcus granulosus serotonin receptor 0.0218 0.0592 0.0592
Schistosoma mansoni cpg binding protein 0.002 0.0026 0.0025
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0022 0.0029 0.0029
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0027 0.0026
Schistosoma mansoni notch 0.0063 0.0147 0.0146
Loa Loa (eye worm) glutaminase 0.016 0.0427 0.0538
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0218 0.0592 0.0592
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0218 0.0592 0.0592
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0013 0.0114
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0082 0.0203 0.0256
Loa Loa (eye worm) glutaminase 2 0.016 0.0427 0.0538
Brugia malayi 6-phosphofructokinase 0.0114 0.0295 0.0371
Trypanosoma cruzi hypothetical protein, conserved 0.0085 0.0211 0.0266
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0019
Brugia malayi hypothetical protein 0.0218 0.0592 0.0747
Echinococcus multilocularis transient receptor potential ion channel A 0.0056 0.0128 0.0127
Onchocerca volvulus 0.0029 0.0051 0.0136
Brugia malayi hypothetical protein 0.0082 0.0201 0.0253
Schistosoma mansoni hypothetical protein 0.0063 0.0147 0.0146
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.0295 0.1932
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0031 0.0202
Trypanosoma brucei DNA polymerase IV, putative 0.0051 0.0113 0.0142
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0218 0.0592 0.0592
Onchocerca volvulus Dual oxidase homolog 0.0463 0.1293 0.352
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0295 0.0371
Loa Loa (eye worm) hypothetical protein 0.022 0.0597 0.0753
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0218 0.0592 0.0592
Schistosoma mansoni biogenic amine receptor 0.0218 0.0592 0.0592
Brugia malayi EGF-like domain containing protein 0.0063 0.0147 0.0185
Brugia malayi Calcitonin receptor-like protein seb-1 0.0237 0.0645 0.0814
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0063 0.0147 0.0399
Echinococcus multilocularis rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0218 0.0592 0.0747
Brugia malayi 6-phosphofructokinase 0.0114 0.0295 0.0371
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0029 0.0051 0.005
Brugia malayi Carboxylesterase family protein 0.0029 0.0051 0.0063
Schistosoma mansoni histone deacetylase hda2 0.0018 0.002 0.0019
Leishmania major mitochondrial DNA polymerase beta 0.0235 0.0639 0.0807
Brugia malayi larval opioid receptor 0.0218 0.0592 0.0747
Loa Loa (eye worm) cytochrome P450 family protein 0.014 0.0369 0.0465
Echinococcus granulosus survival motor neuron protein 1 0.0111 0.0287 0.0286
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0085 0.0211 0.0266
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0016 0.0012 0.0379
Trypanosoma cruzi importin beta-1 subunit, putative 0.0035 0.0067 0.0085
Onchocerca volvulus 0.0218 0.0592 0.1611
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0014
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0031 0.0039
Echinococcus granulosus neuroligin 0.0029 0.0051 0.005
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0017 0.0018 0.0022
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0002 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0027 0.0233
Giardia lamblia DINP protein human, muc B family 0.0035 0.0068 0.4623
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0008 0.0068
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0075 0.0182 0.0181
Schistosoma mansoni sodium-bile acid cotransporter related 0.012 0.0311 0.0311
Onchocerca volvulus Slit protein homolog 0.0063 0.0147 0.0399
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0228 0.0227
Echinococcus multilocularis serotonin receptor 0.0218 0.0592 0.0592
Echinococcus granulosus peroxidasin 0.0463 0.1293 0.1293
Leishmania major cytochrome p450-like protein 0.0082 0.0203 0.0256
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0218 0.0592 0.0592
Brugia malayi ORL1-like opioid receptor 0.0218 0.0592 0.0747
Brugia malayi Inositol-1 0.0017 0.0018 0.0022
Leishmania major hypothetical protein, conserved 0.0015 0.0011 0.0013
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.022 0.0597 0.0596
Echinococcus granulosus transient receptor potential ion channel A 0.0056 0.0128 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0027 0.0233
Brugia malayi Delta serrate ligand family protein 0.0063 0.0147 0.0185
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0022 0.0029 0.0037
Onchocerca volvulus 0.0218 0.0592 0.1611
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0027 0.0233
Schistosoma mansoni notch 0.0063 0.0147 0.0146
Echinococcus granulosus sodium and chloride dependent glycine 0.022 0.0597 0.0596
Echinococcus granulosus tm gpcr rhodopsin 0.0218 0.0592 0.0592
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0218 0.0592 0.0592
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0218 0.0592 0.0592
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0295 0.0371
Loa Loa (eye worm) hypothetical protein 0.022 0.0597 0.0753
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0.0011 0.0169
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0295 0.2627
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0082 0.0203 0.474
Brugia malayi Sodium:neurotransmitter symporter family protein 0.022 0.0597 0.0753
Loa Loa (eye worm) hypothetical protein 0.0029 0.0051 0.0063
Loa Loa (eye worm) hypothetical protein 0.0064 0.015 0.0189
Brugia malayi Animal haem peroxidase family protein 0.0463 0.1293 0.1633
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0354 0.098 0.1237
Leishmania major hypothetical protein, conserved 0.0016 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.014 0.0369 0.864
Echinococcus multilocularis transient receptor potential gamma protein 0.0062 0.0146 0.0145
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0022 0.0029 0.019
Echinococcus granulosus GPCR family 2 0.0075 0.0182 0.0181
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0029
Entamoeba histolytica Ran family GTPase 0.0032 0.0058 0.1963
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.022 0.0597 1
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0094 0.0836
Echinococcus granulosus hyperpolarization activated cyclic 0.0013 0.0006 0.0005
Echinococcus multilocularis survival motor neuron protein 1 0.0111 0.0287 0.0286
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Onchocerca volvulus 0.0014 0.0007 0.0017
Brugia malayi Cytochrome P450 family protein 0.0119 0.0307 0.0388
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.002 0.0024
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0027 0.0033
Trichomonas vaginalis glutaminase, putative 0.016 0.0427 0.3806
Echinococcus granulosus fatty acid binding protein FABP2 0.0036 0.0072 0.0071
Trichomonas vaginalis D-aminoacylase, putative 0.0085 0.0211 0.1882
Schistosoma mansoni cytochrome P450 0.0082 0.0203 0.0202
Onchocerca volvulus 0.0218 0.0592 0.1611
Schistosoma mansoni neuropeptide receptor 0.0218 0.0592 0.0592
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0218 0.0592 0.0592
Echinococcus granulosus neurogenic locus protein delta 0.0063 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0218 0.0592 0.0592
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0001 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Brugia malayi hypothetical protein 0.0029 0.0051 0.0063
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0013 0.0006 0.0007
Echinococcus granulosus hypothetical protein 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Loa Loa (eye worm) animal heme peroxidase 0.0463 0.1293 0.1633
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0056 0.0935
Schistosoma mansoni transient receptor potential channel 0.0062 0.0146 0.0145
Schistosoma mansoni microsomal glutathione s-transferase 0.3506 1 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0218 0.0592 0.0592
Echinococcus multilocularis geminin 0.0576 0.1615 0.1615
Schistosoma mansoni hypothetical protein 0.0082 0.0203 0.0202
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0002 0.0002
Brugia malayi EGF-like domain containing protein 0.0063 0.0147 0.0185
Loa Loa (eye worm) hypothetical protein 0.1419 0.403 0.5091
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0162 0.0431 0.0543
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0027 0.0033
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0027 0.0046 0.0046
Loa Loa (eye worm) cytochrome P450 family protein 0.0119 0.0307 0.0388
Echinococcus multilocularis orexin receptor type 2 0.0218 0.0592 0.0592
Echinococcus granulosus dna polymerase eta 0.0027 0.0046 0.0046
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0031 0.0039
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0013 0.0114
Onchocerca volvulus 0.012 0.0311 0.0846
Giardia lamblia High cysteine protein 0.0063 0.0147 1
Echinococcus multilocularis sodium bile acid cotransporter 0.012 0.0311 0.0311
Onchocerca volvulus 0.0218 0.0592 0.1611
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0056 0.0702
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0006 0.0005
Echinococcus granulosus histone deacetylase 0.0018 0.002 0.0019
Loa Loa (eye worm) matrixin family protein 0.0023 0.0034 0.0043
Echinococcus multilocularis fat cadherin tumor suppressor 0.0063 0.0147 0.0146
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Loa Loa (eye worm) hypothetical protein 0.0111 0.0287 0.0361
Leishmania major importin beta-1 subunit, putative 0.0035 0.0067 0.0085
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0033 0.0062 0.0078
Mycobacterium ulcerans esterase/lipase LipP 0.0085 0.0211 0.4936
Schistosoma mansoni hypothetical protein 0.0218 0.0592 0.0592
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.013 0.085
Loa Loa (eye worm) hypothetical protein 0.0085 0.0211 0.0266
Echinococcus granulosus protein jagged 2 0.0063 0.0147 0.0146
Leishmania major GTP-binding protein, putative 0.0032 0.0058 0.0073
Trypanosoma cruzi C-8 sterol isomerase, putative 0.2777 0.7916 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0085 0.0211 0.0266
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Loa Loa (eye worm) cytochrome P450 0.0082 0.0203 0.0256
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0158 0.0158
Schistosoma mansoni blooms syndrome DNA helicase 0.0013 0.0006 0.0005
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0056 0.0496
Schistosoma mansoni hypothetical protein 0.0063 0.0147 0.0146
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0218 0.0592 0.0592
Echinococcus granulosus TRP transient receptor potential channel 0.0026 0.0042 0.0041
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Brugia malayi Serotonin receptor 0.0218 0.0592 0.0747
Echinococcus granulosus cytochrome P450 2K1 0.0082 0.0203 0.0202
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0158 0.0158
Trypanosoma brucei importin beta-1 subunit, putative 0.0043 0.0091 0.0114
Plasmodium falciparum transporter, putative 0.022 0.0597 1
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.0295 0.6897
Brugia malayi Transient-receptor-potential like protein 0.0026 0.0042 0.0052
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.0295 0.0294
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0082 0.0203 0.1329
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0056 0.0932
Echinococcus granulosus tar DNA binding protein 0.0067 0.0158 0.0158
Brugia malayi hypothetical protein 0.0218 0.0592 0.0747
Loa Loa (eye worm) animal heme peroxidase 0.0463 0.1293 0.1633
Onchocerca volvulus 0.0063 0.0147 0.0399
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0007 0.006
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0075 0.0182 0.0229
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0013 0.0006 0.0005
Schistosoma mansoni neuropeptide f receptor 76f 0.0218 0.0592 0.0592
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0002 0.0002
Schistosoma mansoni notch 0.0063 0.0147 0.0146
Plasmodium falciparum heterochromatin protein 1 0.0012 0.0002 0.0026
Echinococcus multilocularis insulin receptor 0.005 0.0111 0.0111
Treponema pallidum sodium- and chloride- dependent transporter 0.1295 0.3673 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0022 0.0029 0.0037
Brugia malayi Intermediate filament tail domain containing protein 0.0065 0.0154 0.0194
Onchocerca volvulus Chorion peroxidase homolog 0.0463 0.1293 0.352
Schistosoma mansoni transient receptor potential channel 4 0.0062 0.0146 0.0145
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0024
Brugia malayi follicle stimulating hormone receptor 0.0817 0.2306 0.2912
Schistosoma mansoni zinc finger protein 0.0016 0.0014 0.0013
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0031 0.0039
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.0135 0.3147
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0019 0.0019
Onchocerca volvulus 0.0218 0.0592 0.1611
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0135 0.017
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0082 0.0203 0.1329
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0081 0.0102
Schistosoma mansoni hypothetical protein 0.0063 0.0147 0.0146
Loa Loa (eye worm) animal heme peroxidase 0.0463 0.1293 0.1633
Echinococcus multilocularis inositol monophosphatase 1 0.0017 0.0018 0.0017
Schistosoma mansoni chromobox protein 0.0012 0.0002 0.0002
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0011 0.001
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0082 0.0203 0.474
Brugia malayi PXA domain containing protein 0.0021 0.0027 0.0033
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0295 0.0371
Plasmodium vivax histone deacetylase, putative 0.0018 0.002 0.0324
Schistosoma mansoni tyrosine kinase 0.0083 0.0206 0.0206
Schistosoma mansoni growth hormone secretagogue receptor 0.0218 0.0592 0.0592
Toxoplasma gondii isocitrate dehydrogenase 0.0022 0.0029 0.0029
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.022 0.0597 0.0753
Schistosoma mansoni lamin 0.0065 0.0154 0.0153
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0015 0.025
Loa Loa (eye worm) hypothetical protein 0.0171 0.0458 0.0577
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0026 0.0042 0.0041
Schistosoma mansoni lipoxygenase 0.0341 0.0943 0.0943
Trichomonas vaginalis DNA helicase recq1, putative 0.0017 0.0016 0.0138
Trypanosoma cruzi ISWI complex protein 0.0016 0.0014 0.0017
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0029 0.0051 0.0329
Trichomonas vaginalis importin beta-1, putative 0.0035 0.0067 0.0598
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0002 0.0002
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0158 0.0158
Loa Loa (eye worm) carboxylesterase 0.0029 0.0051 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0014
Onchocerca volvulus 0.0063 0.0147 0.0399
Toxoplasma gondii isocitrate dehydrogenase 0.0022 0.0029 0.0029
Leishmania major C-8 sterol isomerase-like protein 0.2777 0.7916 1
Plasmodium falciparum LCCL domain-containing protein 0.0082 0.0201 0.3364
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0001 0.0001
Brugia malayi hypothetical protein 0.0128 0.0334 0.0421
Echinococcus multilocularis microsomal glutathione S transferase 3 0.3506 1 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0543 0.1522 1
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0111 0.0286 0.036
Echinococcus multilocularis lamin dm0 0.0065 0.0154 0.0153
Echinococcus granulosus dna polymerase kappa 0.0058 0.0135 0.0135
Loa Loa (eye worm) carboxylesterase 0.0171 0.0458 0.0577
Entamoeba histolytica hypothetical protein 0.0075 0.0181 0.6143
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Echinococcus multilocularis neuropeptides capa receptor 0.0218 0.0592 0.0592
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.022 0.0598 0.0597
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0031 0.0707
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0082 0.0203 0.474
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0235 0.0639 0.0807
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Echinococcus granulosus neuropeptide Y receptor 0.0218 0.0592 0.0592
Schistosoma mansoni fatty acid binding protein 0.0036 0.0072 0.0071
Loa Loa (eye worm) solute carrier family 6 member 4 0.1295 0.3673 0.464
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0015 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0082 0.0203 0.1329
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0075 0.0182 0.0181
Echinococcus multilocularis neuropeptide Y receptor 0.0218 0.0592 0.0592
Brugia malayi CHD4 protein 0.0015 0.0011 0.0013
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0017 0.0018 0.0152
Echinococcus multilocularis histone deacetylase 6 0.0018 0.002 0.0019
Echinococcus multilocularis fmrfamide receptor 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) CXXC zinc finger family protein 0.0017 0.0017 0.0021
Trypanosoma brucei cytochrome P450, putative 0.014 0.0369 0.0465
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0085 0.0211 0.0266
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0013 0.008
Loa Loa (eye worm) hypothetical protein 0.0041 0.0085 0.0107
Brugia malayi hypothetical protein 0.0021 0.0027 0.0033
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0082 0.0203 0.0256
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0017 0.0018 0.0152
Brugia malayi EGF-like domain containing protein 0.0063 0.0147 0.0185
Brugia malayi hypothetical protein 0.0075 0.0181 0.0228
Onchocerca volvulus 0.0218 0.0592 0.1611
Schistosoma mansoni opsin-like receptor 0.0218 0.0592 0.0592
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0135 0.017
Loa Loa (eye worm) hypothetical protein 0.0069 0.0165 0.0208
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0033 0.0062 0.0078
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0458 0.1279 0.1616
Echinococcus multilocularis epidermal growth factor receptor 0.0157 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0085 0.0211 0.0266
Plasmodium falciparum histone deacetylase 2 0.0018 0.002 0.0321
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0056 0.0932
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0031 0.0707
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0002 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0082 0.0203 0.1329
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0052
Schistosoma mansoni tyrosine kinase 0.005 0.0111 0.0111
Schistosoma mansoni sodium/chloride dependent transporter 0.1295 0.3673 0.3673
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0017 0.0015 0.0015
Brugia malayi CXXC zinc finger family protein 0.0017 0.0017 0.0021
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0056 0.0496
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Echinococcus granulosus beta LACTamase domain containing family member 0.0085 0.0211 0.0211
Brugia malayi neuropeptide F receptor 0.0218 0.0592 0.0747
Loa Loa (eye worm) hypothetical protein 0.0029 0.0051 0.0063
Echinococcus granulosus insulin receptor 0.005 0.0111 0.0111
Echinococcus granulosus cpg binding protein 0.002 0.0026 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0135 0.017
Brugia malayi regulator of G-protein signaling egl-10 0.0026 0.0042 0.0052
Loa Loa (eye worm) hypothetical protein 0.022 0.0597 0.0753
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0002 0.0002
Loa Loa (eye worm) G-protein coupled receptor 0.0218 0.0592 0.0747
Onchocerca volvulus 0.0017 0.0017 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0135 0.017
Echinococcus multilocularis short transient receptor potential channel 6 0.0043 0.009 0.0089
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0218 0.0592 0.0592
Onchocerca volvulus Neurogenic locus notch homolog 0.0063 0.0147 0.0399
Brugia malayi Carboxylesterase family protein 0.0171 0.0458 0.0577
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0135 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0014
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1295 0.3673 0.464
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0027 0.0026
Mycobacterium ulcerans hypothetical protein 0.0022 0.0031 0.0707
Trichomonas vaginalis set domain proteins, putative 0.0402 0.112 1
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0006 0.0005
Schistosoma mansoni sodium/chloride dependent transporter 0.022 0.0597 0.0596
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Brugia malayi Animal haem peroxidase family protein 0.0463 0.1293 0.1633
Onchocerca volvulus 0.0402 0.112 0.3047
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0038 0.0038
Brugia malayi Cadherin domain containing protein 0.0063 0.0147 0.0185
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0027 0.0026
Plasmodium falciparum histone deacetylase, putative 0.0018 0.002 0.0321
Echinococcus multilocularis expressed protein 0.04 0.1112 0.1112
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.022 0.0597 0.0596
Brugia malayi hypothetical protein 0.0218 0.0592 0.0747
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0027 0.0026
Echinococcus granulosus delta-like protein 1 0.0063 0.0147 0.0146
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0017 0.0018 0.0022
Loa Loa (eye worm) hypothetical protein 0.0043 0.0091 0.0114
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0218 0.0592 0.0747
Mycobacterium tuberculosis Probable lipase LipD 0.0085 0.0211 0.1384
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0011 0.001
Brugia malayi GnHR receptor homolog 0.0218 0.0592 0.0747
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0029 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0082 0.0203 0.1329
Schistosoma mansoni amine GPCR 0.0218 0.0592 0.0592
Onchocerca volvulus 0.0029 0.0051 0.0136
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0027 0.0033
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0087 0.0086
Onchocerca volvulus 0.0032 0.006 0.0161
Plasmodium vivax amine transporter, putative 0.022 0.0597 1
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Schistosoma mansoni bromodomain containing protein 0.0067 0.0161 0.016
Schistosoma mansoni septate junction protein 0.0063 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Trichomonas vaginalis DNA helicase recq, putative 0.0017 0.0016 0.0138
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0022 0.0031 0.0707
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0018
Leishmania major cytochrome p450-like protein 0.0082 0.0203 0.0256
Brugia malayi Calcium binding EGF domain containing protein 0.0063 0.0147 0.0185
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.013 0.0163
Schistosoma mansoni histamine h1 receptor 0.0218 0.0592 0.0592
Echinococcus multilocularis g protein coupled receptor 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0124
Plasmodium vivax hypothetical protein, conserved 0.022 0.0597 1
Echinococcus granulosus short transient receptor potential channel 6 0.0043 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0019
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.0002 0.0002
Brugia malayi Animal haem peroxidase family protein 0.0463 0.1293 0.1633
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0031 0.0039
Onchocerca volvulus Peroxidase homolog 0.0463 0.1293 0.352
Echinococcus granulosus neurogenic locus notch protein 0.0063 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0218 0.0592 0.0592
Echinococcus granulosus g protein coupled receptor 0.0218 0.0592 0.0592
Echinococcus granulosus fibropellin Ia 0.0063 0.0147 0.0146
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.013 0.0352
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0035 0.0067 0.0598
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0082 0.0203 0.1329
Loa Loa (eye worm) hypothetical protein 0.1295 0.3673 0.464
Schistosoma mansoni hypothetical protein 0.0458 0.1279 0.1279
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0017 0.0015 0.0015
Brugia malayi hypothetical protein 0.0218 0.0592 0.0747
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0056 0.3794
Brugia malayi Blistered cuticle protein 3 0.0463 0.1293 0.1633
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0218 0.0592 0.0592
Leishmania major histone deacetylase, putative 0.0018 0.002 0.0024
Brugia malayi Dopamine receptor protein 1 0.0218 0.0592 0.0747
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0113 0.0292 0.0792
Echinococcus granulosus uncharacterized sodium dependent transporter 0.022 0.0597 0.0596
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0014
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0031 0.0058 0.0057
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Onchocerca volvulus 0.0218 0.0592 0.1611
Echinococcus granulosus histone deacetylase 6 0.0018 0.002 0.0019
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0063 0.0147 0.0185
Toxoplasma gondii MAPEG family protein 0.3506 1 1
Schistosoma mansoni gliotactin 0.0029 0.0051 0.005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0013 0.0114
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.0295 0.0801
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.003 0.0037
Echinococcus granulosus neurogenic locus notch protein 4 0.0063 0.0147 0.0146
Brugia malayi Carboxylesterase family protein 0.0171 0.0458 0.0577
Schistosoma mansoni hypothetical protein 0.0075 0.0181 0.0181
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0218 0.0592 0.0592
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0082 0.0203 0.474
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.022 0.0597 0.0597
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0082 0.0203 0.0256
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0029 0.0051 0.005
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0295 0.2627
Trichomonas vaginalis Heterochromatin protein, putative 0.0012 0.0002 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0218 0.0592 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0051 0.045
Onchocerca volvulus 0.0012 0.0002 0.0004
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0022 0.0029 0.0029
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0032 0.0058 0.3941
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0085 0.0757
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0056 0.0496
Brugia malayi RNA, U transporter 1 0.0122 0.0317 0.04
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.022 0.0597 0.0596
Brugia malayi Heterochromatin protein 1 0.0073 0.0177 0.0223
Echinococcus granulosus epidermal growth factor receptor 0.0084 0.0209 0.0208
Brugia malayi isocitrate dehydrogenase 0.0022 0.0029 0.0037
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0002 0.0014
Echinococcus granulosus neuropeptide FF receptor 2 0.0218 0.0592 0.0592
Schistosoma mansoni opsin-like receptor 0.0218 0.0592 0.0592
Brugia malayi N-terminal motif family protein 0.0113 0.0292 0.0368
Loa Loa (eye worm) hypothetical protein 0.0022 0.0031 0.0039
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0031 0.0039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0218 0.0592 0.0592
Loa Loa (eye worm) matrixin family protein 0.0021 0.0029 0.0036
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0032 0.0058 0.0073
Echinococcus granulosus protein jagged 1 0.0063 0.0147 0.0146
Echinococcus granulosus orexin receptor type 2 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0085 0.021 0.0265
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0011 0.0001 0.0003
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0082 0.0203 0.474
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0817 0.2306 0.2912
Loa Loa (eye worm) Notch2 0.0063 0.0147 0.0185
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0027 0.0026
Echinococcus granulosus zinc finger protein 0.0022 0.003 0.0029
Trypanosoma brucei DNA polymerase eta, putative 0.0027 0.0046 0.0058
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0228 0.0287
Trypanosoma brucei importin beta-1 subunit, putative 0.0043 0.0091 0.0114
Trypanosoma brucei histone deacetylase, putative 0.0018 0.002 0.0024
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0085 0.0211 0.0211
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0013 0.008
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0085 0.0211 0.0266
Brugia malayi Muscle positioning protein 4 0.0063 0.0147 0.0185
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.015 0.015
Brugia malayi Carboxylesterase family protein 0.0029 0.0051 0.0063
Mycobacterium tuberculosis Probable hydrolase 0.0085 0.0211 0.1384
Brugia malayi beta-lactamase 0.0085 0.0211 0.0266
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0085 0.0211 0.0211
Echinococcus granulosus G protein coupled receptor 139 0.0218 0.0592 0.0592
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0135 0.017
Trichomonas vaginalis ran, putative 0.0032 0.0058 0.0516
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0024
Entamoeba histolytica hypothetical protein 0.0021 0.0027 0.0886
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0002 0.0014
Plasmodium vivax exodeoxyribonuclease III, putative 0.0011 0.0001 0.0003
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.013 0.0163
Echinococcus multilocularis neuropeptide FF receptor 2 0.0218 0.0592 0.0592
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0044 0.0055
Echinococcus granulosus neuropeptide receptor 0.0218 0.0592 0.0592
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0218 0.0592 0.0592
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0075 0.0181 0.0181
Schistosoma mansoni notch 0.0063 0.0147 0.0146
Entamoeba histolytica hypothetical protein 0.0012 0.0002 0.0053
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.0013
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0022 0.0031 0.0707
Brugia malayi Protein kinase domain containing protein 0.005 0.0111 0.014
Loa Loa (eye worm) hypothetical protein 0.0333 0.0921 0.1163
Echinococcus granulosus dnaJ subfamily B 0.0246 0.0671 0.0671
Echinococcus multilocularis acetylcholinesterase 0.0171 0.0458 0.0457
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0096 0.0096
Onchocerca volvulus 0.0085 0.0211 0.0573
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0082 0.0203 0.474
Brugia malayi Matrixin family protein 0.0023 0.0034 0.0043
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0082 0.0203 0.474
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0027 0.0026
Plasmodium vivax SET domain protein, putative 0.0051 0.0114 0.1904
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Entamoeba histolytica acyl-CoA synthetase, putative 0.0022 0.0031 0.1048
Onchocerca volvulus 0.0218 0.0592 0.1611
Brugia malayi hypothetical protein 0.0082 0.0201 0.0253
Loa Loa (eye worm) hypothetical protein 0.0043 0.009 0.0113
Mycobacterium leprae putative cytochrome p450 0.0082 0.0203 0.6872
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0022 0.0029 0.0485
Plasmodium vivax importin-beta 2, putative 0.0043 0.0091 0.1514
Echinococcus granulosus rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Leishmania major histone deacetylase, putative 0.0018 0.002 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0082 0.0203 0.1329
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.3506 1 1
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0082 0.0203 0.474
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0295 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0015 0.033
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0033 0.0062 0.0078
Schistosoma mansoni hypothetical protein 0.0014 0.0007 0.0006
Echinococcus granulosus acetylcholinesterase 0.0171 0.0458 0.0457
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0032 0.0058 0.0968
Echinococcus granulosus bloom syndrome protein 0.0017 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0029 0.0051 0.0063
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0002 0.0014
Echinococcus granulosus neurogenic locus notch protein 0.0063 0.0147 0.0146
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0056 0.0496
Schistosoma mansoni neuropeptide receptor 0.0218 0.0592 0.0592
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1295 0.3673 0.3673
Toxoplasma gondii ABC1 family protein 0.0085 0.0211 0.0211
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0295 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0085 0.0757
Echinococcus granulosus g protein coupled receptor 0.0218 0.0592 0.0592
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0013 0.0114
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0015 0.001 0.016
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0148 0.0148
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0085 0.0211 0.1384
Loa Loa (eye worm) hypothetical protein 0.0123 0.0321 0.0404
Echinococcus granulosus regulator of G protein signaling 7 0.0026 0.0042 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0068 0.0086
Trichomonas vaginalis inositol monophosphatase, putative 0.0017 0.0018 0.0152
Entamoeba histolytica acyl-CoA synthetase, putative 0.0022 0.0031 0.1048
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0135 0.017
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0033 0.0062 0.0078
Schistosoma mansoni sodium-dependent amino acid transporter 0.022 0.0597 0.0596
Leishmania major DNA polymerase kappa, putative 0.0035 0.0068 0.0086
Loa Loa (eye worm) TK/INSR protein kinase 0.005 0.0111 0.014
Echinococcus granulosus lipoxygenase domain containing protein 0.0082 0.0201 0.0201
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Echinococcus multilocularis lamin 0.0065 0.0154 0.0153
Echinococcus multilocularis Polycystic kidney disease protein 0.0082 0.0201 0.0201
Echinococcus granulosus snurportin 1 0.0458 0.1279 0.1279
Toxoplasma gondii LsmAD domain-containing protein 0.0015 0.0011 0.0011
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0058 0.0135 0.1202
Brugia malayi Carboxylesterase family protein 0.0029 0.0051 0.0063
Echinococcus granulosus rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0012 0.0001 0.0001
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0035 0.0068 0.0067
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0063 0.0147 0.0146
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.0135 0.3147
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0022 0.0029 0.0488
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0056 0.0496
Brugia malayi Hemopexin family protein 0.0014 0.0007 0.0008
Trypanosoma cruzi ISWI complex protein 0.0016 0.0014 0.0017
Brugia malayi Peroxidasin 0.0463 0.1293 0.1633
Onchocerca volvulus Huntingtin homolog 0.0123 0.0321 0.0872
Schistosoma mansoni fatty acid binding protein 0.0036 0.0072 0.0071
Echinococcus multilocularis sodium and chloride dependent glycine 0.022 0.0597 0.0596
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus multilocularis fatty acid binding protein FABP2 0.0036 0.0072 0.0071
Schistosoma mansoni inositol monophosphatase 0.0017 0.0018 0.0017
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.013 0.0163
Trypanosoma cruzi PAB1-binding protein , putative 0.0015 0.0011 0.0013
Brugia malayi Bromodomain containing protein 0.008 0.0196 0.0247
Schistosoma mansoni biogenic amine receptor 0.0218 0.0592 0.0592
Echinococcus granulosus neuropeptide Y receptor 0.0218 0.0592 0.0592
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0022 0.0029 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0076 0.0075
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0158 0.0199
Brugia malayi cytochrome P450 0.0082 0.0203 0.0256
Echinococcus multilocularis protein jagged 1 0.0063 0.0147 0.0146
Onchocerca volvulus 0.0218 0.0592 0.1611
Trypanosoma cruzi cytochrome P450, putative 0.014 0.0369 0.0465
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.022 0.0597 0.0596
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Brugia malayi Carboxylesterase family protein 0.0029 0.0051 0.0063
Schistosoma mansoni intermediate filament proteins 0.0065 0.0154 0.0153
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0002 0.0029
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Mycobacterium tuberculosis Carboxylesterase LipT 0.0029 0.0051 0.0329
Brugia malayi RNA binding protein 0.0067 0.0158 0.0199
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0027 0.0026
Mycobacterium tuberculosis Probable lipase LipE 0.0085 0.0211 0.1384
Mycobacterium ulcerans glutaminase 0.016 0.0427 1
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0027 0.0026
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.013 0.8833
Loa Loa (eye worm) hypothetical protein 0.0123 0.0321 0.0404
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0033
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Echinococcus granulosus g protein coupled receptor 0.0218 0.0592 0.0592
Onchocerca volvulus 0.0065 0.0154 0.0417
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0033
Brugia malayi Isocitrate dehydrogenase 0.0022 0.0029 0.0037
Echinococcus granulosus neuropeptide s receptor 0.0218 0.0592 0.0592
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0049 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0068
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0031 0.1026
Loa Loa (eye worm) hypothetical protein 0.1295 0.3673 0.464
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0035 0.0067 0.0598
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0082 0.0203 0.0256
Echinococcus multilocularis hyperpolarization activated cyclic 0.0013 0.0006 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0135 0.017
Echinococcus granulosus RUN 0.0082 0.0201 0.0201
Schistosoma mansoni amine GPCR 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0036 0.0072 0.009
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.022 0.0597 0.0597
Echinococcus multilocularis histone deacetylase 6 0.0018 0.002 0.0019
Schistosoma mansoni hypothetical protein 0.0218 0.0592 0.0592
Schistosoma mansoni polycystin 1-related 0.0082 0.0201 0.0201
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0135 0.017
Brugia malayi hypothetical protein 0.0021 0.0027 0.0033
Loa Loa (eye worm) neuropeptide F receptor 0.0218 0.0592 0.0747
Echinococcus granulosus fmrfamide receptor 0.0218 0.0592 0.0592
Onchocerca volvulus 0.0029 0.0051 0.0136
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Brugia malayi Animal haem peroxidase family protein 0.0463 0.1293 0.1633
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0056 0.0935
Mycobacterium ulcerans lipase LipD 0.0085 0.0211 0.4936
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0158 0.0158
Schistosoma mansoni rab6-interacting 0.0082 0.0201 0.0201
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0094 0.0836
Schistosoma mansoni hypothetical protein 0.0576 0.1615 0.1615
Brugia malayi phosphofructokinase 0.0114 0.0295 0.0371
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0017 0.0018 0.0022
Brugia malayi hypothetical protein 0.0218 0.0592 0.0747
Brugia malayi EGF-like domain containing protein 0.0063 0.0147 0.0185
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0065 0.0154 0.0194
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0218 0.0592 0.0747
Schistosoma mansoni amine GPCR 0.0218 0.0592 0.0592
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0027 0.0046 0.0046
Brugia malayi PXA domain containing protein 0.0021 0.0027 0.0033
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0082 0.0203 0.1329
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0082 0.0203 0.1329
Loa Loa (eye worm) G-protein coupled receptor 0.0218 0.0592 0.0747
Onchocerca volvulus 0.0218 0.0592 0.1611
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.022 0.0597 0.0596
Brugia malayi Bromodomain containing protein 0.004 0.0083 0.0104
Echinococcus multilocularis hyperpolarization activated cyclic 0.0013 0.0006 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0081 0.0102
Schistosoma mansoni alpha-1 adrenergic receptor 0.0218 0.0592 0.0592
Schistosoma mansoni hypothetical protein 0.0218 0.0592 0.0592
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.004 0.0081 0.0102
Echinococcus multilocularis dna polymerase eta 0.0027 0.0046 0.0046
Onchocerca volvulus 0.0218 0.0592 0.1611
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0082 0.0203 0.474
Echinococcus multilocularis neuropeptide receptor 0.0218 0.0592 0.0592
Onchocerca volvulus 0.0218 0.0592 0.1611
Echinococcus multilocularis neuropeptide receptor 0.0218 0.0592 0.0592
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0027 0.0026
Brugia malayi intermediate filament protein 0.0065 0.0154 0.0194
Echinococcus multilocularis 0.0048 0.0107 0.0106
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0026 0.0042 0.0052
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0235 0.0639 0.0807
Schistosoma mansoni tyrosine kinase 0.005 0.0111 0.0111
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0135 0.017
Brugia malayi PHD-finger family protein 0.0027 0.0046 0.0057
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.022 0.0597 0.0596
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Brugia malayi notch-like transmembrane receptor 0.0063 0.0147 0.0185
Loa Loa (eye worm) doublecortin family protein 0.0082 0.0201 0.0253
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0027 0.0026
Brugia malayi Cytochrome P450 family protein 0.014 0.0369 0.0465
Onchocerca volvulus 0.022 0.0597 0.1624
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0165 0.0165
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0087 0.0109
Entamoeba histolytica hypothetical protein 0.0075 0.0181 0.6143
Schistosoma mansoni hypothetical protein 0.0022 0.003 0.0029
Schistosoma mansoni hypothetical protein 0.0012 0.0002 0.0002
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0017 0.0018 0.0018
Echinococcus multilocularis chromobox protein 1 0.0073 0.0177 0.0177
Echinococcus granulosus somatostatin receptor 0.0218 0.0592 0.0592
Echinococcus multilocularis RUN 0.0082 0.0201 0.0201
Onchocerca volvulus 0.0218 0.0592 0.1611
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Schistosoma mansoni sodium/chloride dependent transporter 0.022 0.0597 0.0596
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0488 0.1363 0.1363
Loa Loa (eye worm) RNA binding protein 0.0067 0.0158 0.0199
Onchocerca volvulus 0.0218 0.0592 0.1611
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0006 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0044 0.0055
Schistosoma mansoni inositol monophosphatase 0.0017 0.0018 0.0017
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.0295 0.0294
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Schistosoma mansoni biogenic amine (5HT) receptor 0.0218 0.0592 0.0592
Onchocerca volvulus 0.0063 0.0147 0.0399
Schistosoma mansoni ap endonuclease 0.0057 0.013 0.0129
Schistosoma mansoni histone deacetylase 4 5 0.0018 0.002 0.0019
Schistosoma mansoni tyrosine kinase 0.0084 0.0209 0.0208
Loa Loa (eye worm) hypothetical protein 0.0029 0.0051 0.0063
Entamoeba histolytica deoxycytidyl transferase, putative 0.0027 0.0046 0.1553
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0463 0.1293 0.1633
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0013 0.0114
Schistosoma mansoni notch 0.0063 0.0147 0.0146
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0228 0.0227
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0013 0.008
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0082 0.0203 0.1329
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Trypanosoma cruzi DNA polymerase eta, putative 0.0027 0.0046 0.0058
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0016 0.0012 0.0078
Loa Loa (eye worm) acetylcholinesterase 1 0.0171 0.0458 0.0577
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0036 0.0072 0.009
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0218 0.0592 0.0747
Echinococcus granulosus sodium bile acid cotransporter 0.012 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0019
Brugia malayi hypothetical protein 0.0218 0.0592 0.0747
Echinococcus multilocularis short transient receptor potential channel 6 0.0043 0.009 0.0089
Loa Loa (eye worm) cytochrome P450 family protein 0.014 0.0369 0.0465
Echinococcus granulosus 7tm_1 domain containing protein 0.0218 0.0592 0.0592
Echinococcus multilocularis rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Onchocerca volvulus 0.0218 0.0592 0.1611
Brugia malayi SET domain containing protein 0.0014 0.0009 0.001
Echinococcus multilocularis neurogenic locus protein delta 0.0063 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0085 0.0211 0.0266
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0002 0.0002
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0085 0.0231
Echinococcus multilocularis para nitrobenzyl esterase 0.0029 0.0051 0.005
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.015 0.015
Onchocerca volvulus Neuropeptide F receptor homolog 0.0218 0.0592 0.1611
Schistosoma mansoni laminin gamma-3 chain 0.0063 0.0147 0.0146
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.013 0.0129
Plasmodium falciparum importin beta, putative 0.0043 0.0091 0.1512
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0295 0.2627
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0029 0.0051 0.005
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0295 0.0294
Schistosoma mansoni survival motor neuron protein 0.0023 0.0033 0.0032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0007
Echinococcus granulosus neuropeptides capa receptor 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0074 0.018 0.0227
Echinococcus granulosus Polycystic kidney disease protein 0.0082 0.0201 0.0201
Schistosoma mansoni hypothetical protein 0.0023 0.0033 0.0032
Loa Loa (eye worm) serotonin transporter b 0.1295 0.3673 0.464
Leishmania major cytochrome p450-like protein 0.014 0.0369 0.0465
Brugia malayi Melatonin receptor type 1A 0.0218 0.0592 0.0747
Brugia malayi Latrophilin receptor protein 2 0.0075 0.0182 0.0229
Echinococcus granulosus notch 0.0063 0.0147 0.0146
Mycobacterium ulcerans carboxylesterase, LipT 0.0029 0.0051 0.116
Echinococcus multilocularis chromobox protein 1 0.0073 0.0177 0.0177
Echinococcus multilocularis neuropeptide receptor A26 0.0218 0.0592 0.0592
Onchocerca volvulus 0.0082 0.0201 0.0546
Brugia malayi ImpB/MucB/SamB family protein 0.0027 0.0046 0.0058
Brugia malayi Dopamine receptor 0.0218 0.0592 0.0747
Loa Loa (eye worm) inositol-1 0.0017 0.0018 0.0022
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0019 0.0019
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0008 0.0068
Brugia malayi AKH receptor 0.0218 0.0592 0.0747
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0082 0.0203 0.0256
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0084
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.013 0.2169
Loa Loa (eye worm) hypothetical protein 0.1295 0.3673 0.464
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0218 0.0592 0.0592
Echinococcus granulosus acetylcholinesterase 0.0171 0.0458 0.0457
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0014
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0022 0.0029 0.0037
Echinococcus granulosus importin subunit beta 1 0.0043 0.0091 0.009
Toxoplasma gondii histone deacetylase HDAC1 0.0018 0.002 0.002
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0087 0.0109
Trichomonas vaginalis esterase, putative 0.0085 0.0211 0.1882
Echinococcus granulosus sodium and chloride dependent glycine 0.022 0.0597 0.0596
Onchocerca volvulus 0.0218 0.0592 0.1611
Brugia malayi Serotonin receptor 0.0218 0.0592 0.0747
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0082 0.0203 0.474
Schistosoma mansoni sodium-bile acid cotransporter 0.0056 0.0129 0.0128
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0002 0.0002
Schistosoma mansoni neuropeptide F-like receptor 0.0218 0.0592 0.0592
Brugia malayi Doublecortin family protein 0.0082 0.0201 0.0253
Mycobacterium tuberculosis Probable esterase LipL 0.0085 0.0211 0.1384
Schistosoma mansoni neuroligin 3 (S09 family) 0.0029 0.0051 0.005
Brugia malayi Sodium:neurotransmitter symporter family protein 0.022 0.0597 0.0753
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0228 0.0227
Onchocerca volvulus 0.0082 0.0201 0.0546
Echinococcus granulosus lamin 0.0065 0.0154 0.0153
Toxoplasma gondii cytochrome p450 superfamily protein 0.0082 0.0203 0.0203
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0218 0.0592 0.0592
Plasmodium vivax multidomain scavenger receptor, putative 0.0082 0.0201 0.3366
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0022 0.0029 0.0029
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0228 0.0227
Echinococcus multilocularis allatostatin A receptor 0.0218 0.0592 0.0592
Schistosoma mansoni acetylcholinesterase 0.0029 0.0051 0.005
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0027 0.0026
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0082 0.0203 0.474
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0218 0.0592 0.0592
Onchocerca volvulus 0.0029 0.0051 0.0136
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0135 0.017
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.013 0.3025
Echinococcus granulosus rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.013 0.1156
Echinococcus multilocularis neurogenic locus notch protein 0.0063 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0085 0.0211 0.0266
Onchocerca volvulus 0.0012 0.0002 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0082 0.0203 0.1329
Echinococcus granulosus dro:myosuppressin receptor 0.0218 0.0592 0.0592
Loa Loa (eye worm) melatonin receptor type 1A 0.0218 0.0592 0.0747
Echinococcus granulosus regulator of G protein signaling 7 0.0026 0.0042 0.0041
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0036 0.0072 0.009
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0029 0.0051 0.0329
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0295 0.0294
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0228 0.0287
Mycobacterium ulcerans beta-lactamase 0.0085 0.0211 0.4936
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0032 0.0058 0.0058
Onchocerca volvulus 0.0085 0.0211 0.0573
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0237 0.0645 0.0814
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.013 0.2171
Schistosoma mansoni hypothetical protein 0.0246 0.0671 0.0671
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0002 0.0053
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0002 0.0002
Trypanosoma brucei histone deacetylase 3 0.0018 0.002 0.0024
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0027 0.0046 0.0058
Echinococcus granulosus biogenic amine 5HT receptor 0.0218 0.0592 0.0592
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0488 0.1363 0.1363
Echinococcus multilocularis fatty acid binding protein FABP2 0.0036 0.0072 0.0071
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0082 0.0203 0.474
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0218 0.0592 0.0592
Brugia malayi EGF-like domain containing protein 0.0063 0.0147 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0228 0.0227
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0015 0.0247
Toxoplasma gondii EGF family domain-containing protein 0.0063 0.0147 0.0147
Schistosoma mansoni DNA polymerase eta 0.0027 0.0046 0.0046
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.022 0.0597 0.0596
Loa Loa (eye worm) hypothetical protein 0.0113 0.0292 0.0368
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Loa Loa (eye worm) TYRA-2 protein 0.0218 0.0592 0.0747
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0022 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0237 0.0645 0.0814
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0031 0.0707
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0218 0.0592 0.0592
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0158 0.0199
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0114 0.0113
Echinococcus granulosus sodium bile acid cotransporter 0.012 0.0311 0.0311
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0002 0.0029
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0027 0.0033
Loa Loa (eye worm) histone deacetylase 7A 0.0018 0.002 0.0024
Onchocerca volvulus 0.0463 0.1293 0.352
Echinococcus granulosus para nitrobenzyl esterase 0.0029 0.0051 0.005
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0082 0.0201 0.0253
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0068
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0075 0.0181 0.0181
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0177 0.1579
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.013 1
Brugia malayi putative neuropeptide receptor NPR1 0.0218 0.0592 0.0747
Schistosoma mansoni neuropeptide receptor 0.0218 0.0592 0.0592
Onchocerca volvulus Matrilysin homolog 0.0021 0.0029 0.0077
Echinococcus multilocularis dnaJ subfamily B 0.0246 0.0671 0.0671
Echinococcus granulosus carboxylesterase 5A 0.0171 0.0458 0.0457
Loa Loa (eye worm) hypothetical protein 0.0075 0.0182 0.0229
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0218 0.0592 0.0592
Trichomonas vaginalis hypothetical protein 0.0012 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0069 0.0612
Brugia malayi sulfakinin receptor protein 0.0218 0.0592 0.0747
Echinococcus granulosus rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Echinococcus granulosus lipoxygenase domain containing protein 0.0082 0.0201 0.0201
Trichomonas vaginalis D-aminoacylase, putative 0.0085 0.0211 0.1882
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0044 0.0055
Loa Loa (eye worm) blistered cuticle protein 3 0.0463 0.1293 0.1633
Echinococcus granulosus chromobox protein 1 0.0073 0.0177 0.0177
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.022 0.0598 0.0597
Brugia malayi Bloom's syndrome protein homolog 0.0017 0.0016 0.0019
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0031 0.0058 0.0057
Echinococcus granulosus lamin dm0 0.0065 0.0154 0.0153
Echinococcus multilocularis histone deacetylase 6 0.0018 0.002 0.0019
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0027 0.0026
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.013 0.4399
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0082 0.0203 0.474
Loa Loa (eye worm) hypothetical protein 0.022 0.0597 0.0753
Brugia malayi Furin-like cysteine rich region family protein 0.0157 0.0416 0.0525
Plasmodium vivax histone deacetylase 2, putative 0.0018 0.002 0.0324
Mycobacterium leprae conserved hypothetical protein 0.0085 0.0211 0.7157
Echinococcus granulosus hormone sensitive lipase 0.022 0.0598 0.0597
Schistosoma mansoni ran 0.0032 0.0058 0.0058
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0069 0.0165 0.0165
Schistosoma mansoni chromobox protein 0.0073 0.0177 0.0177
Schistosoma mansoni chromobox protein 0.0073 0.0177 0.0177
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0027 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Echinococcus multilocularis musashi 0.0065 0.0154 0.0153
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0085 0.0211 0.1384
Brugia malayi hypothetical protein 0.0111 0.0287 0.0361
Trichomonas vaginalis D-aminoacylase, putative 0.0085 0.0211 0.1882
Loa Loa (eye worm) transcription factor SMAD2 0.0072 0.0173 0.0218
Toxoplasma gondii HEAT repeat-containing protein 0.0043 0.0091 0.0091
Echinococcus granulosus alpha 1A adrenergic receptor 0.0218 0.0592 0.0592
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0082 0.0203 0.474
Echinococcus granulosus neuropeptide receptor A26 0.0218 0.0592 0.0592
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.002 0.0024
Brugia malayi hypothetical protein 0.0012 0.0002 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0085 0.0211 0.3534
Echinococcus multilocularis sodium and chloride dependent glycine 0.022 0.0597 0.0596
Loa Loa (eye worm) hypothetical protein 0.0082 0.0201 0.0253
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0082 0.0203 0.474
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0228 0.0227
Loa Loa (eye worm) hypothetical protein 0.0029 0.0051 0.0063
Echinococcus granulosus tachykinin peptides receptor 99D 0.0218 0.0592 0.0592
Schistosoma mansoni hypothetical protein 0.0576 0.1615 0.1615
Echinococcus granulosus chromobox protein 2 0.0012 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0063 0.0147 0.0146
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0002 0.0014
Brugia malayi Cadherin domain containing protein 0.0063 0.0147 0.0185
Echinococcus multilocularis G-protein coupled receptor, putative 0.0218 0.0592 0.0592
Echinococcus granulosus histone deacetylase 7 0.0018 0.002 0.0019
Schistosoma mansoni hypothetical protein 0.0063 0.0147 0.0146
Brugia malayi TAR-binding protein 0.0067 0.0158 0.0199
Echinococcus granulosus epidermal growth factor receptor 0.0157 0.0416 0.0416
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0042 0.0041
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0022 0.0029 0.0037
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0002 0.0053
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0295 0.2627
Echinococcus granulosus transient receptor potential gamma protein 0.0062 0.0146 0.0145
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0218 0.0592 0.0592
Schistosoma mansoni loxhd1 0.0082 0.0201 0.0201
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0027 0.0233
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Echinococcus granulosus inositol monophosphatase 1 0.0017 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.012 0.0311 0.0393
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0027 0.0033
Brugia malayi G-protein coupled receptor 0.0218 0.0592 0.0747
Echinococcus multilocularis rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Schistosoma mansoni myosin xvIII 0.0218 0.0592 0.0592
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0013 0.0006 0.0005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0013 0.0114
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0013 0.0006 0.0047
Brugia malayi Histone deacetylase family protein 0.0018 0.002 0.0024
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0027 0.0026
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0032 0.0058 0.0073
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0027 0.0026
Echinococcus granulosus uncharacterized sodium dependent transporter 0.022 0.0597 0.0596
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0027 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0056 0.0496
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0022 0.0029 0.0037
Schistosoma mansoni biogenic amine (5HT) receptor 0.0218 0.0592 0.0592
Trichomonas vaginalis DNA polymerase eta, putative 0.0058 0.0135 0.1202
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0032 0.0058 0.0058
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0295 1
Schistosoma mansoni tyrosine kinase 0.0157 0.0416 0.0416
Schistosoma mansoni hypothetical protein 0.0075 0.0182 0.0181
Trypanosoma brucei unspecified product 0.0051 0.0113 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Schistosoma mansoni cell polarity protein 0.0063 0.0147 0.0146
Schistosoma mansoni rab6-interacting 0.0082 0.0201 0.0201
Schistosoma mansoni glutaminase 0.016 0.0427 0.0426
Echinococcus multilocularis rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Echinococcus multilocularis dro:myosuppressin receptor 0.0218 0.0592 0.0592
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0111 0.0286 0.036
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Onchocerca volvulus 0.0029 0.0051 0.0136
Mycobacterium ulcerans hypothetical protein 0.0124 0.0321 0.7528
Toxoplasma gondii hypothetical protein 0.022 0.0597 0.0597
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0013 0.0006 0.0005
Echinococcus granulosus tm gpcr rhodopsin 0.0952 0.2691 0.2691
Leishmania major pantothenate kinase subunit, putative 0.0012 0.0003 0.0003
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0218 0.0592 0.0747
Schistosoma mansoni transient receptor potential channel 0.0043 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0029 0.0051 0.0063
Schistosoma mansoni hypothetical protein 0.0082 0.0201 0.0201
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0013 0.0114
Brugia malayi ImpB/MucB/SamB family protein 0.0027 0.0046 0.0058
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0013 0.0006 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0082 0.0203 0.1329
Toxoplasma gondii exonuclease III APE 0.0057 0.013 0.013
Trypanosoma cruzi PAB1-binding protein , putative 0.0015 0.0011 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0027 0.0233
Echinococcus granulosus protein jagged 1 0.0063 0.0147 0.0146
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0027 0.0026
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0218 0.0592 0.0592
Trypanosoma cruzi cytochrome P450, putative 0.014 0.0369 0.0465
Echinococcus granulosus hyperpolarization activated cyclic 0.0013 0.0006 0.0005
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0002 0.0002
Trypanosoma brucei hypothetical protein, conserved 0.0085 0.0211 0.0266
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.0295 0.0371
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0.0011 0.0169
Trypanosoma brucei C-8 sterol isomerase, putative 0.2777 0.7916 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0031 0.0039
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.013 0.0163
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0218 0.0592 0.0592
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0017 0.0018 0.058
Schistosoma mansoni sodium-bile acid cotransporter related 0.0064 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0002 0.0014
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0096 0.0096
Schistosoma mansoni notch 0.0063 0.0147 0.0146
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0031 0.1026
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0177 0.0223
Brugia malayi beta-lactamase family protein 0.0085 0.0211 0.0266
Echinococcus multilocularis dna polymerase kappa 0.0058 0.0135 0.0135
Echinococcus multilocularis slit 2 protein 0.0063 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.022 0.0597 0.0753
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0228 0.0227
Schistosoma mansoni chromobox protein 0.0012 0.0002 0.0002
Mycobacterium tuberculosis Conserved hypothetical protein 0.0124 0.0321 0.2108
Schistosoma mansoni tyrosine kinase 0.0083 0.0206 0.0206
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0011 0.001
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0011 0.0001 0.0003
Trichomonas vaginalis spcc417.12 protein, putative 0.0029 0.0051 0.0447
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0029 0.0051 0.0447
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0029 0.0051 0.005
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0085 0.0211 0.1384
Brugia malayi G-protein coupled receptor 0.0218 0.0592 0.0747
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0032 0.0058 0.0073
Mycobacterium leprae Probable lipase LipE 0.0085 0.0211 0.7157
Brugia malayi RE15519p 0.0218 0.0592 0.0747
Mycobacterium tuberculosis Conserved protein 0.0085 0.0211 0.1384
Echinococcus multilocularis g protein coupled receptor 0.0218 0.0592 0.0592
Entamoeba histolytica hypothetical protein 0.0075 0.0181 0.6143
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0218 0.0592 0.0592
Onchocerca volvulus 0.0463 0.1293 0.352
Echinococcus granulosus slit 2 protein 0.0063 0.0147 0.0146
Echinococcus granulosus allatostatin A receptor 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Onchocerca volvulus Putative cubilin 0.0063 0.0147 0.0399
Echinococcus multilocularis serotonin transporter 0.1295 0.3673 0.3673
Brugia malayi Pre-SET motif family protein 0.0051 0.0114 0.0143
Onchocerca volvulus 0.0463 0.1293 0.352
Trypanosoma brucei unspecified product 0.0019 0.0022 0.0027
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0001 0.0001
Echinococcus multilocularis isocitrate dehydrogenase 0.0022 0.0029 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Schistosoma mansoni opsin-like receptor 0.0218 0.0592 0.0592
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0027 0.0033
Leishmania major DNA polymerase eta, putative 0.0027 0.0046 0.0058
Brugia malayi Calcium binding EGF domain containing protein 0.0063 0.0147 0.0185
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0013 0.0006 0.0047
Echinococcus multilocularis GPCR, family 2 0.0075 0.0182 0.0181
Onchocerca volvulus Matrix metalloproteinase homolog 0.0021 0.0029 0.0077
Loa Loa (eye worm) TK/EGFR protein kinase 0.0157 0.0416 0.0525
Echinococcus granulosus rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Echinococcus granulosus short transient receptor potential channel 6 0.0043 0.009 0.0089
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.022 0.0597 0.0596
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Brugia malayi Calcium binding EGF domain containing protein 0.0063 0.0147 0.0185
Brugia malayi G protein-coupled receptor 0.0218 0.0592 0.0747
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0056 0.0056
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0031 0.0058 0.0072
Schistosoma mansoni hypothetical protein 0.0016 0.0014 0.0013
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0056 0.0151
Brugia malayi Histone deacetylase family protein 0.0018 0.002 0.0024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0165 0.0165
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0056 0.0056
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0082 0.0203 0.474
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.022 0.0597 0.0596
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0032 0.0058 0.0073
Trichomonas vaginalis penicillin-binding protein, putative 0.0085 0.0211 0.1882
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0218 0.0592 0.0592
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0082 0.0203 0.474
Brugia malayi hypothetical protein 0.022 0.0597 0.0753
Echinococcus granulosus BC026374 protein S09 family 0.0029 0.0051 0.005
Brugia malayi G protein-coupled receptor F59B2.13 0.0218 0.0592 0.0747
Trypanosoma brucei PAB1-binding protein , putative 0.0015 0.0011 0.0013
Echinococcus multilocularis snurportin 1 0.0458 0.1279 0.1279
Loa Loa (eye worm) hypothetical protein 0.0029 0.0051 0.0063
Loa Loa (eye worm) hypothetical protein 0.0065 0.0154 0.0194
Brugia malayi hypothetical protein 0.0218 0.0592 0.0747
Echinococcus multilocularis sodium bile acid cotransporter 0.012 0.0311 0.0311
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0006 0.0005
Entamoeba histolytica acyl-coA synthetase, putative 0.0022 0.0031 0.1048
Echinococcus granulosus histone deacetylase 6 0.0018 0.002 0.0019
Brugia malayi Dopamine receptor protein 2 0.0218 0.0592 0.0747
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0027 0.0026
Brugia malayi beta-lactamase family protein 0.0085 0.0211 0.0266
Echinococcus granulosus voltage gated potassium channel 0.0017 0.0015 0.0015
Loa Loa (eye worm) helicase 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0022 0.0031 0.0084
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0021 0.0026
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0013 0.0006 0.0005
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.022 0.0597 0.0596
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0032 0.0058 0.0073
Brugia malayi MH2 domain containing protein 0.0072 0.0173 0.0218
Onchocerca volvulus Huntingtin homolog 0.0123 0.0321 0.0872
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0027 0.0046 0.0046
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0237 0.0645 0.0814
Brugia malayi Pre-SET motif family protein 0.0354 0.098 0.1237
Echinococcus multilocularis regulator of G protein signaling 7 0.0026 0.0042 0.0041
Echinococcus multilocularis BC026374 protein (S09 family) 0.0029 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.2777 0.7916 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0134 0.0168
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0082 0.0203 0.1329
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.013 0.0163
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.022 0.0597 0.0596
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0177 0.1579
Echinococcus multilocularis epidermal growth factor receptor 0.0084 0.0209 0.0208
Schistosoma mansoni adenoreceptor 0.0218 0.0592 0.0592
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0218 0.0592 0.0747
Schistosoma mansoni terminal deoxycytidyl transferase 0.0027 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Brugia malayi hypothetical protein 0.0463 0.1293 0.1633
Brugia malayi Sodium:neurotransmitter symporter family protein 0.022 0.0597 0.0753
Echinococcus multilocularis sex peptide receptor 0.0218 0.0592 0.0592
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0032 0.006 0.0075
Schistosoma mansoni tyrosine kinase 0.0084 0.0209 0.0208
Echinococcus granulosus histone deacetylase 6 0.0018 0.002 0.0019
Entamoeba histolytica hypothetical protein 0.0012 0.0002 0.0053
Onchocerca volvulus Peroxidase homolog 0.0463 0.1293 0.352
Brugia malayi hypothetical protein 0.0218 0.0592 0.0747
Brugia malayi Importin beta-1 subunit 0.0043 0.0091 0.0114
Schistosoma mansoni peroxidasin 0.0463 0.1293 0.1293
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0135 0.017
Echinococcus multilocularis histone deacetylase 7 0.0018 0.002 0.0019
Echinococcus multilocularis beta LACTamase domain containing family member 0.0085 0.0211 0.0211
Echinococcus granulosus neuropeptide receptor 0.0218 0.0592 0.0592
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0019 0.0019
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0035 0.0067 0.0084
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0051 0.0114 0.0114
Loa Loa (eye worm) notch protein 0.0063 0.0147 0.0185
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0022 0.0029 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Onchocerca volvulus 0.1295 0.3673 1
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.022 0.0598 0.0755
Echinococcus multilocularis rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Brugia malayi EGF-like domain containing protein 0.0063 0.0147 0.0185
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0218 0.0592 0.0592
Trypanosoma brucei ISWI complex protein 0.0016 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0006 0.0005
Onchocerca volvulus 0.0063 0.0148 0.0402
Schistosoma mansoni ap endonuclease 0.0057 0.013 0.0129
Schistosoma mansoni hypothetical protein 0.0218 0.0592 0.0592
Echinococcus multilocularis histone deacetylase 0.0018 0.002 0.0019
Onchocerca volvulus 0.0065 0.0154 0.0417
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0051 0.045
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0013 0.0006 0.0005
Schistosoma mansoni histone deacetylase 4 5 0.0018 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.004 0.0083 0.0104
Brugia malayi chromobox protein homolog 3 0.0041 0.0085 0.0107
Brugia malayi ERG2 and Sigma1 receptor like protein 0.2777 0.7916 1
Schistosoma mansoni neuropeptide receptor 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0056 0.0496
Echinococcus granulosus intermediate filament protein 0.0065 0.0154 0.0153
Echinococcus multilocularis lipoxygenase domain containing protein 0.0082 0.0201 0.0201
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0218 0.0592 0.0747
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0015 0.0015
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0075 0.0182 0.0181
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.013 0.0129
Mycobacterium ulcerans hypothetical protein 0.0085 0.0211 0.4936
Mycobacterium tuberculosis Conserved protein 0.0085 0.0211 0.1384
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0218 0.0592 0.0592
Echinococcus multilocularis fibropellin Ia 0.0063 0.0147 0.0146
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0038 0.0078 0.0077
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0082 0.0203 0.1329
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0218 0.0592 0.0592
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0082 0.0203 0.1329
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0051 0.0114 0.0113
Echinococcus multilocularis neurogenic locus protein delta 0.0063 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0058
Echinococcus granulosus insulin growth factor 1 receptor beta 0.005 0.0111 0.0111
Brugia malayi hypothetical protein 0.0015 0.0011 0.0013
Echinococcus multilocularis g-protein coupled receptor 0.0218 0.0592 0.0592
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0218 0.0592 0.0592
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0022 0.0031 0.0707
Schistosoma mansoni lamin 0.0065 0.0154 0.0153
Echinococcus multilocularis somatostatin receptor 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.022 0.0598 0.0597
Loa Loa (eye worm) carboxylesterase 0.0029 0.0051 0.0063
Echinococcus granulosus protein jagged 2 0.0063 0.0147 0.0146
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.022 0.0597 0.0597
Echinococcus granulosus geminin 0.0576 0.1615 0.1615
Brugia malayi Animal haem peroxidase family protein 0.0463 0.1293 0.1633
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Loa Loa (eye worm) phosphofructokinase 0.0114 0.0295 0.0371
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0218 0.0592 0.0592
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0295 0.0371
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0027 0.0026
Echinococcus multilocularis g protein coupled receptor 0.0218 0.0592 0.0592
Echinococcus granulosus histone lysine methyltransferase setb 0.0069 0.0165 0.0165
Entamoeba histolytica hypothetical protein 0.0035 0.0067 0.2276
Echinococcus multilocularis neuropeptide Y receptor 0.0218 0.0592 0.0592
Echinococcus multilocularis cpg binding protein 0.002 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0063 0.0147 0.0185
Trypanosoma cruzi hypothetical protein, conserved 0.0085 0.0211 0.0266
Schistosoma mansoni importin beta-1 0.0043 0.0091 0.009
Echinococcus multilocularis protein jagged 1 0.0063 0.0147 0.0146
Schistosoma mansoni cpg binding protein 0.002 0.0026 0.0025
Echinococcus granulosus neuropeptides capa receptor 0.0218 0.0592 0.0592
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0027 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0218 0.0592 0.0592
Loa Loa (eye worm) animal heme peroxidase 0.0463 0.1293 0.1633
Onchocerca volvulus Peroxidasin homolog 0.0463 0.1293 0.352
Plasmodium vivax ataxin-2 like protein, putative 0.0015 0.0011 0.0173
Echinococcus multilocularis acetylcholinesterase 0.0171 0.0458 0.0457
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0001 0.0001
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0006 0.0005
Schistosoma mansoni hypothetical protein 0.0075 0.0182 0.0181
Schistosoma mansoni hypothetical protein 0.0075 0.0182 0.0181
Echinococcus multilocularis neural cadherin 0.0063 0.0147 0.0146
Brugia malayi hypothetical protein 0.0218 0.0592 0.0747
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0218 0.0592 0.0592
Schistosoma mansoni biogenic amine receptor 0.0218 0.0592 0.0592
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0013 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0171 0.0458 0.0577
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0011 0.0001 0.0001
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0075 0.0182 0.0181
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Echinococcus granulosus peptide allatostatin:somatostatin 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0022 0.0031 0.0039
Loa Loa (eye worm) norepinephrine transporter 0.1295 0.3673 0.464
Toxoplasma gondii hypothetical protein 0.022 0.0597 0.0597
Schistosoma mansoni peroxidasin 0.0463 0.1293 0.1293
Echinococcus granulosus serotonin transporter 0.1295 0.3673 0.3673
Loa Loa (eye worm) intermediate filament protein 0.0065 0.0154 0.0194
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0023 0.0033 0.0032
Mycobacterium tuberculosis Conserved protein 0.0085 0.0211 0.1384
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.022 0.0597 0.0753
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0019
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0218 0.0592 0.0747
Echinococcus multilocularis G protein coupled receptor 139 0.0218 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0218 0.0592 0.0747
Echinococcus multilocularis regulator of G protein signaling 7 0.0026 0.0042 0.0041

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 0.095 uM Concentration required to inhibit K562 cell growth ChEMBL. 12951086
IC50 (functional) = 0.095 uM Concentration required to inhibit K562 cell growth ChEMBL. 12951086
IC50 (functional) = 1 uM Concentration required to inhibit HT-29 cell growth ChEMBL. 12951086
IC50 (functional) = 1 uM Concentration required to inhibit HT-29 cell growth ChEMBL. 12951086
IC50 (functional) = 89.7 uM Concentration required to inhibit MRC-5 cell growth ChEMBL. 12951086
IC50 (functional) = 89.7 uM Concentration required to inhibit MRC-5 cell growth ChEMBL. 12951086
IC50 (functional) = 1000 uM Concentration required to inhibit HL-60 cell growth ChEMBL. 12951086
IC50 (functional) > 1000 uM Concentration required to inhibit MCF-7 cell growth ChEMBL. 12951086
IC50 (functional) = 1000 uM Concentration required to inhibit HL-60 cell growth ChEMBL. 12951086
IC50 (functional) > 1000 uM Concentration required to inhibit MCF-7 cell growth ChEMBL. 12951086

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 12951086

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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