Detailed information for compound 289770

Basic information

Technical information
  • TDR Targets ID: 289770
  • Name: 4-[(E)-3-(3-hydroxy-5,5,8,8-tetramethyl-6,7-d ihydronaphthalen-2-yl)-3-oxoprop-1-enyl]benzo ic acid
  • MW: 378.461 | Formula: C24H26O4
  • H donors: 2 H acceptors: 4 LogP: 6.54 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1cc2c(cc1O)C(C)(C)CCC2(C)C)/C=C/c1ccc(cc1)C(=O)O
  • InChi: 1S/C24H26O4/c1-23(2)11-12-24(3,4)19-14-21(26)17(13-18(19)23)20(25)10-7-15-5-8-16(9-6-15)22(27)28/h5-10,13-14,26H,11-12H2,1-4H3,(H,27,28)/b10-7+
  • InChiKey: COJYSQDHRBWLLU-JXMROGBWSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-[(E)-3-(7-hydroxy-1,1,4,4-tetramethyl-tetralin-6-yl)-3-oxo-prop-1-enyl]benzoic acid
  • 4-[(E)-3-(7-hydroxy-1,1,4,4-tetramethyl-6-tetralinyl)-3-oxoprop-1-enyl]benzoic acid
  • 4-[(E)-3-(3-hydroxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-3-oxo-prop-1-enyl]benzoic acid
  • 4-[(E)-3-(7-hydroxy-1,1,4,4-tetramethyl-tetralin-6-yl)-3-keto-prop-1-enyl]benzoic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0098 0.024 0.0308
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0065 0.0147 0.0147
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0029 0.0037
Brugia malayi Animal haem peroxidase family protein 0.2727 0.7781 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0065 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Brugia malayi glutathione reductase 0.005 0.0101 0.013
Brugia malayi Sugar transporter family protein 0.0014 0.0001 0.0001
Schistosoma mansoni notch 0.0485 0.1351 0.1351
Schistosoma mansoni hypothetical protein 0.0485 0.1351 0.1351
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0051 0.0106 0.0106
Trichomonas vaginalis aldo/keto reductase, putative 0.0111 0.0279 0.1384
Plasmodium vivax unspecified product 0.0026 0.0034 0.0306
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0086 0.0424
Echinococcus granulosus Ankyrin 0.0015 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.014 0.0362 0.0465
Echinococcus granulosus protein jagged 1 0.0485 0.1351 0.1351
Onchocerca volvulus Peroxidase homolog 0.2727 0.7781 1
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0001 0.0003
Echinococcus granulosus L aminoadipate semialdehyde 0.0173 0.0456 0.0456
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0051 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0249 0.0673 0.0673
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0437 0.2169
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0065 0.0147 0.0147
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0108 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0038 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0037 0.0064 0.0339
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0003 0.0003
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0108 0.027 0.027
Mycobacterium ulcerans short chain dehydrogenase 0.0044 0.0084 0.0443
Schistosoma mansoni histone deacetylase 0.0398 0.1101 0.1101
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.009 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0075 0.0397
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0059 0.0291
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0002 0.0002
Mycobacterium ulcerans oxidoreductase 0.0111 0.0279 0.1474
Echinococcus multilocularis dnaJ subfamily B 0.0427 0.1183 0.1183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0035 0.017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0017
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.0013 0.0017
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0065 0.0147 0.0147
Echinococcus multilocularis cathepsin L 0.0026 0.0034 0.0034
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0105 0.0135
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0008 0.0039
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.0383 0.0493
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0017
Onchocerca volvulus 0.0485 0.1351 0.1735
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.0059 0.0313
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Onchocerca volvulus 0.0044 0.0084 0.0108
Entamoeba histolytica alcohol dehydrogenase, putative 0.0045 0.0089 0.0804
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0057 0.0124 0.0124
Schistosoma mansoni ap endonuclease 0.0056 0.0121 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.006 0.0295
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0075 0.0397
Schistosoma mansoni histamine h1 receptor 0.0065 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.007 0.0372
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0783 0.389
Echinococcus granulosus phd:f box containing protein 0.0015 0.0003 0.0003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0065 0.0147 0.0189
Echinococcus multilocularis neuropeptide Y receptor 0.0065 0.0147 0.0147
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.007 0.0346
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0002 0.0002
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0001 0.0003
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.0375 0.0375
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0019 0.0098
Brugia malayi ORL1-like opioid receptor 0.0065 0.0147 0.0189
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0065 0.0147 0.0147
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0008 0.0045
Plasmodium falciparum glutathione reductase 0.0017 0.0008 0.0071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0783 0.389
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0105 0.0953
Brugia malayi Animal haem peroxidase family protein 0.2727 0.7781 1
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0075 0.0394
Loa Loa (eye worm) hypothetical protein 0.0108 0.027 0.0347
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0065 0.0147 0.0147
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0008 0.0045
Echinococcus multilocularis neuropeptide s receptor 0.1956 0.5569 0.5569
Brugia malayi jmjC domain containing protein 0.0058 0.0125 0.0161
Trichomonas vaginalis histone deacetylase, putative 0.0398 0.1101 0.5472
Brugia malayi Sugar transporter family protein 0.0014 0.0001 0.0001
Echinococcus granulosus methionine synthase reductase 0.0016 0.0006 0.0006
Brugia malayi EGF-like domain containing protein 0.0485 0.1351 0.1736
Echinococcus granulosus dna polymerase kappa 0.004 0.0075 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0053 0.0263
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0108 0.027 0.027
Schistosoma mansoni nuclear receptor 0.0051 0.0106 0.0106
Brugia malayi major facilitator superfamily protein 0.0014 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.006 0.0295
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Loa Loa (eye worm) cytochrome P450 0.0037 0.0064 0.0082
Echinococcus granulosus lipoxygenase domain containing protein 0.014 0.0362 0.0362
Echinococcus granulosus 7tm_1 domain containing protein 0.0065 0.0147 0.0147
Echinococcus granulosus lipoxygenase domain containing protein 0.014 0.0362 0.0362
Schistosoma mansoni zinc finger protein 0.0051 0.0106 0.0106
Echinococcus multilocularis neurogenic locus notch protein 0.0485 0.1351 0.1351
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0028 0.0134
Onchocerca volvulus 0.0065 0.0147 0.0188
Plasmodium vivax aldehyde reductase, putative 0.0045 0.0089 0.0799
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Toxoplasma gondii glyoxalase I, putative 0.0189 0.0501 0.3708
Brugia malayi nuclear receptor NHR-67 0.0051 0.0106 0.0136
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0194 0.0515 0.0515
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0075 0.0397
Brugia malayi Intermediate filament tail domain containing protein 0.011 0.0276 0.0355
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0147
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0783 0.389
Schistosoma mansoni intermediate filament proteins 0.011 0.0276 0.0276
Trypanosoma cruzi histone deacetylase, putative 0.0143 0.0368 0.1952
Echinococcus granulosus Solute carrier family 22 5 0.2033 0.5792 0.5792
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Echinococcus granulosus neural cadherin 0.0485 0.1351 0.1351
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0017 0.0007 0.0009
Schistosoma mansoni sugar transporter 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0028 0.0134
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Loa Loa (eye worm) notch protein 0.0485 0.1351 0.1736
Echinococcus granulosus cathepsin L 0.0026 0.0034 0.0034
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0001 0.0001
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0125 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0108 0.027 0.0347
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0034 0.0181
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0008 0.0042
Onchocerca volvulus 0.0044 0.0084 0.0108
Brugia malayi major facilitator superfamily protein 0.0014 0.0001 0.0001
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0002 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0105 0.0556
Echinococcus multilocularis lipoxygenase domain containing protein 0.014 0.0362 0.0362
Schistosoma mansoni myosin xvIII 0.0065 0.0147 0.0147
Schistosoma mansoni polycystin 1-related 0.014 0.0362 0.0362
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0044 0.0084 0.0108
Schistosoma mansoni hypothetical protein 0.0346 0.0953 0.0953
Schistosoma mansoni hypothetical protein 0.0098 0.024 0.024
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Brugia malayi Phospholipase A2 family protein 0.0274 0.0746 0.0959
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0019 0.0098
Brugia malayi steroid hormone receptor 0.0108 0.027 0.0347
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0001 0.0001
Onchocerca volvulus 0.0065 0.0147 0.0188
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0108 0.027 0.0347
Brugia malayi Tachykinin-like peptides receptor 99D 0.0065 0.0147 0.0189
Schistosoma mansoni histone deacetylase hda2 0.0143 0.0368 0.0368
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0147
Trypanosoma brucei glucose transporter, putative 0.0014 0.0001 0.0003
Loa Loa (eye worm) histone deacetylase 7A 0.0143 0.0368 0.0473
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0045 0.0089 0.0469
Schistosoma mansoni opsin-like receptor 0.0065 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0189 0.0501 0.0644
Echinococcus granulosus RUN 0.014 0.0362 0.0362
Plasmodium falciparum pyruvate kinase 0.0035 0.0059 0.0531
Schistosoma mansoni cpg binding protein 0.0063 0.0141 0.0141
Onchocerca volvulus 0.0051 0.0105 0.0134
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Leishmania major hypothetical protein, conserved 0.0026 0.0033 0.0172
Onchocerca volvulus 0.0099 0.0245 0.0313
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0006 0.0031
Onchocerca volvulus 0.0065 0.0147 0.0188
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0026 0.0035 0.0183
Schistosoma mansoni adenoreceptor 0.0065 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Echinococcus granulosus neuropeptide receptor A26 0.1956 0.5569 0.5569
Trypanosoma brucei glucose transporter, putative 0.0014 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0002 0.0002
Echinococcus granulosus fibropellin Ia 0.0485 0.1351 0.1351
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Loa Loa (eye worm) CYP4Cod1 0.0046 0.009 0.0116
Leishmania major cathepsin L-like protease 0.0193 0.0514 0.2724
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0001 0.0003
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0101 0.0537
Onchocerca volvulus 0.0173 0.0456 0.0585
Brugia malayi Doublecortin family protein 0.014 0.0362 0.0465
Schistosoma mansoni histone deacetylase hda2 0.0143 0.0368 0.0368
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0037
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0001 0.0003
Leishmania major cytochrome p450-like protein 0.0037 0.0064 0.0339
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0035 0.017
Echinococcus granulosus notch 0.0485 0.1351 0.1351
Loa Loa (eye worm) hypothetical protein 0.0108 0.027 0.0347
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0099 0.0893
Echinococcus granulosus hypothetical protein 0.0111 0.0279 0.0279
Leishmania major pyruvate kinase 0.0035 0.0059 0.0313
Brugia malayi EGF-like domain containing protein 0.0485 0.1351 0.1736
Echinococcus granulosus arachidonate 5 lipoxygenase 0.084 0.237 0.237
Brugia malayi hypothetical protein 0.014 0.0362 0.0465
Mycobacterium ulcerans glyoxalase GloA 0.0044 0.0085 0.0445
Mycobacterium ulcerans hypothetical protein 0.0044 0.0085 0.0445
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0189 0.0501 0.2655
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0437 0.2169
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0003 0.0004
Brugia malayi Serotonin receptor 0.0065 0.0147 0.0189
Schistosoma mansoni pol-related 0.0111 0.0279 0.0279
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0038 0.0048
Echinococcus granulosus cysteine protease 0.0026 0.0034 0.0034
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0038 0.0049
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0059 0.0291
Schistosoma mansoni histone deacetylase 0.0398 0.1101 0.1101
Loa Loa (eye worm) histone deacetylase 0.0143 0.0368 0.0473
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0783 0.389
Trichomonas vaginalis sulfite reductase, putative 0.0026 0.0035 0.0169
Loa Loa (eye worm) TYRA-2 protein 0.0065 0.0147 0.0189
Brugia malayi hypothetical protein 0.0065 0.0147 0.0189
Brugia malayi Dopamine receptor protein 2 0.0065 0.0147 0.0189
Giardia lamblia Pyruvate kinase 0.0035 0.0059 0.0433
Plasmodium falciparum thioredoxin reductase 0.0017 0.0008 0.0071
Onchocerca volvulus 0.0027 0.0038 0.0048
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0026 0.0035 0.0183
Entamoeba histolytica aldose reductase, putative 0.0111 0.0279 0.2532
Onchocerca volvulus 0.0051 0.0105 0.0134
Schistosoma mansoni biogenic amine receptor 0.0065 0.0147 0.0147
Echinococcus granulosus neuropeptide FF receptor 2 0.0065 0.0147 0.0147
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0075 0.0397
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0023 0.0026 0.0126
Plasmodium vivax multidomain scavenger receptor, putative 0.014 0.0362 0.3287
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0044 0.0217
Echinococcus granulosus tm gpcr rhodopsin 0.0065 0.0147 0.0147
Trypanosoma brucei THT1 - hexose transporter, putative 0.0014 0.0001 0.0003
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0065 0.0147 0.0147
Echinococcus multilocularis fatty acid binding protein FABP2 0.0034 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0514 0.2724
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0037 0.0064 0.0335
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0059 0.0076
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0082 0.0403
Loa Loa (eye worm) hypothetical protein 0.0035 0.0059 0.0076
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.0783 1
Schistosoma mansoni hypothetical protein 0.014 0.0362 0.0362
Echinococcus granulosus survival motor neuron protein 1 0.0471 0.1309 0.1309
Brugia malayi FAD binding domain containing protein 0.0016 0.0006 0.0007
Echinococcus multilocularis 0.0045 0.0089 0.0089
Loa Loa (eye worm) oxidoreductase 0.0111 0.0279 0.0358
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0026 0.0035 0.0183
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0086 0.0086
Onchocerca volvulus Phospholipase A2 homolog 0.0274 0.0746 0.0958
Loa Loa (eye worm) hypothetical protein 0.0091 0.0221 0.0284
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0065 0.0147 0.0147
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0049 0.0099 0.052
Brugia malayi intermediate filament protein 0.011 0.0276 0.0355
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0053 0.0263
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0008 0.0071
Brugia malayi Histone deacetylase family protein 0.0143 0.0368 0.0473
Schistosoma mansoni hypothetical protein 0.0065 0.0147 0.0147
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0108 0.027 0.027
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0001 0.0001
Echinococcus multilocularis lamin 0.011 0.0276 0.0276
Echinococcus granulosus solute carrier family 22 0.0014 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0108 0.027 0.0347
Schistosoma mansoni amine GPCR 0.0065 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Plasmodium falciparum nitric oxide synthase, putative 0.0026 0.0035 0.0308
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0026 0.0035 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0089 0.0437
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0108 0.027 0.0347
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0485 0.1351 0.1735
Echinococcus multilocularis epidermal growth factor receptor 0.0079 0.0185 0.0185
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.018 0.018
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0108 0.027 0.027
Brugia malayi Cathepsin L-like precursor 0.0034 0.0057 0.0073
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0082 0.0736
Onchocerca volvulus Lactoylglutathione lyase homolog 0.0189 0.0501 0.0643
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.018 0.018
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0462 0.2297
Brugia malayi jmjC domain containing protein 0.0015 0.0003 0.0004
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0125 0.0125
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0002 0.0009
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0003 0.0003
Brugia malayi Histone deacetylase 1 0.0398 0.1101 0.1414
Brugia malayi Cathepsin L-like precursor 0.0034 0.0057 0.0073
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0059 0.0076
Echinococcus granulosus protein jagged 2 0.0485 0.1351 0.1351
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0279 0.1384
Loa Loa (eye worm) ctsf protein 0.0051 0.0105 0.0135
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0034 0.0167
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0437 0.2169
Echinococcus multilocularis histone deacetylase 6 0.0143 0.0368 0.0368
Echinococcus multilocularis lamin dm0 0.011 0.0276 0.0276
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0147
Trypanosoma cruzi hexose transporter 0.0014 0.0001 0.0003
Loa Loa (eye worm) doublecortin family protein 0.014 0.0362 0.0465
Plasmodium vivax glyoxalase I, putative 0.0044 0.0085 0.0764
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0086 0.0455
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0065 0.0147 0.0189
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0037 0.0064 0.0339
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0065 0.0147 0.0147
Brugia malayi Latrophilin receptor protein 2 0.0098 0.024 0.0308
Mycobacterium ulcerans pyruvate kinase 0.0035 0.0059 0.0309
Trypanosoma brucei glucose transporter 1E 0.0014 0.0001 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0009 0.0044
Brugia malayi Furin-like cysteine rich region family protein 0.0146 0.0379 0.0488
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0009
Echinococcus multilocularis cysteine protease 0.0051 0.0105 0.0105
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0037 0.0064 0.0335
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0212 0.0212
Entamoeba histolytica cysteine proteinase 2 0.0026 0.0034 0.0311
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0137
Brugia malayi hypothetical protein 0.0057 0.0124 0.0159
Brugia malayi tailless protein 0.0051 0.0106 0.0136
Onchocerca volvulus 0.0111 0.0279 0.0357
Brugia malayi FAD binding domain containing protein 0.0026 0.0035 0.0044
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0049 0.0099 0.0728
Loa Loa (eye worm) hypothetical protein 0.0274 0.0746 0.0959
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Echinococcus multilocularis voltage gated potassium channel subunit 0.0045 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0084 0.0108
Schistosoma mansoni nuclear receptor 0.0051 0.0106 0.0106
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0086 0.0455
Echinococcus granulosus neuropeptide receptor 0.0065 0.0147 0.0147
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0279 0.0279
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0221 0.0221
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0006 0.0031
Brugia malayi Histone deacetylase family protein 0.0143 0.0368 0.0473
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0038 0.0049
Onchocerca volvulus 0.0065 0.0147 0.0188
Brugia malayi hypothetical protein 0.0065 0.0147 0.0189
Echinococcus granulosus aldo keto reductase 0.0111 0.0279 0.0279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0004
Schistosoma mansoni glucose transport protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.0059 0.0076
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0033 0.029
Onchocerca volvulus Protein ultraspiracle homolog 0.0108 0.027 0.0346
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0279 0.1384
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0034 0.0056 0.0073
Brugia malayi hypothetical protein 0.0014 0.0001 0.0001
Brugia malayi hypothetical protein 0.0065 0.0147 0.0189
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0003 0.0003
Plasmodium falciparum LCCL domain-containing protein 0.014 0.0362 0.3287
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0108 0.027 0.0347
Leishmania major histone deacetylase, putative 0.0398 0.1101 0.5831
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0003 0.0003
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.001 0.0073
Schistosoma mansoni RAR-like nuclear receptor 0.0108 0.027 0.027
Brugia malayi Cathepsin L-like precursor 0.0051 0.0105 0.0135
Onchocerca volvulus 0.0485 0.1351 0.1735
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0108 0.027 0.0347
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0514 0.2724
Onchocerca volvulus 0.0065 0.0147 0.0188
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0046 0.009 0.0474
Brugia malayi Animal haem peroxidase family protein 0.2727 0.7781 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0002 0.0009
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0059 0.0313
Echinococcus multilocularis aldo keto reductase 0.0111 0.0279 0.0279
Brugia malayi Nuclear hormone receptor-like 1 0.0108 0.027 0.0347
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0057 0.0515
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.0059 0.0313
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0279 0.1384
Schistosoma mansoni loxhd1 0.014 0.0362 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0108 0.027 0.0347
Brugia malayi hypothetical protein 0.0014 0.0001 0.0001
Echinococcus multilocularis notch 0.0485 0.1351 0.1351
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0065 0.0147 0.0147
Schistosoma mansoni nuclear hormone receptor 0.0108 0.027 0.027
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0047 0.0093 0.0093
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0147 0.0147
Echinococcus granulosus neuropeptide Y receptor 0.0065 0.0147 0.0147
Brugia malayi CXXC zinc finger family protein 0.006 0.0131 0.0168
Schistosoma mansoni organic anion transporter 0.0027 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0049
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0037 0.0064 0.0339
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0065 0.0147 0.0147
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0075 0.0397
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0051 0.0106 0.0106
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0037 0.0064 0.0335
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0105 0.0519
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0687 0.3414
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0105 0.0105
Echinococcus granulosus 7TM GPCR rhodopsin 0.0065 0.0147 0.0147
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0398 0.1101 0.5472
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0065 0.0147 0.0147
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0105 0.0135
Schistosoma mansoni hypothetical protein 0.0485 0.1351 0.1351
Trypanosoma cruzi histone deacetylase 1, putative 0.0398 0.1101 0.5831
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0037 0.0064 0.0339
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Echinococcus granulosus delta-like protein 1 0.0485 0.1351 0.1351
Schistosoma mansoni hypothetical protein 0.0077 0.0181 0.0181
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0514 0.2724
Echinococcus granulosus FTZ F1 alpha 0.0108 0.027 0.027
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0003 0.0003
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0051 0.0106 0.0136
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.003 0.0147
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Entamoeba histolytica hypothetical protein 0.0077 0.0181 0.1642
Loa Loa (eye worm) TK/EGFR protein kinase 0.0146 0.0379 0.0488
Echinococcus granulosus cathepsin l1 0.0051 0.0105 0.0105
Schistosoma mansoni neuropeptide f receptor 76f 0.0065 0.0147 0.0147
Onchocerca volvulus 0.0044 0.0084 0.0108
Onchocerca volvulus 0.0065 0.0147 0.0188
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0004
Brugia malayi EGF-like domain containing protein 0.0485 0.1351 0.1736
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0008 0.0011
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0011 0.0011
Loa Loa (eye worm) blistered cuticle protein 3 0.2727 0.7781 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0003 0.0003
Schistosoma mansoni histone deacetylase 1 2 3 0.0143 0.0368 0.0368
Brugia malayi N-terminal motif family protein 0.0192 0.0511 0.0657
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Echinococcus granulosus G protein coupled receptor 139 0.0065 0.0147 0.0147
Brugia malayi Cadherin domain containing protein 0.0485 0.1351 0.1736
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0029 0.0262
Trypanosoma brucei histone deacetylase, putative 0.0143 0.0368 0.1952
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0026 0.0035 0.0183
Brugia malayi hypothetical protein 0.016 0.0419 0.0538
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.0124 0.0159
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0514 0.2724
Entamoeba histolytica aldose reductase, putative 0.0111 0.0279 0.2532
Mycobacterium ulcerans glyoxalase GloA 0.0044 0.0085 0.0445
Brugia malayi Serotonin receptor 0.0065 0.0147 0.0189
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0059 0.0076
Echinococcus multilocularis nuclear receptor nhr 48 0.0051 0.0106 0.0106
Echinococcus granulosus fmrfamide receptor 0.0065 0.0147 0.0147
Brugia malayi Protein kinase domain containing protein 0.0015 0.0002 0.0003
Trichomonas vaginalis aldo-keto reductase, putative 0.0045 0.0089 0.0437
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0361 0.1915
Loa Loa (eye worm) sugar transporter 0.0014 0.0001 0.0001
Loa Loa (eye worm) histone deacetylase 1 0.0398 0.1101 0.1414
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0045 0.0089 0.0651
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0013 0.0013
Onchocerca volvulus 0.0027 0.0038 0.0048
Plasmodium vivax unspecified product 0.0017 0.0007 0.0061
Brugia malayi hypothetical protein 0.0065 0.0147 0.0189
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0106 0.0106
Brugia malayi SET domain containing protein 0.0016 0.0005 0.0006
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0065 0.0147 0.0147
Onchocerca volvulus 0.014 0.0362 0.0465
Trypanosoma brucei THT1 - hexose transporter, putative 0.0014 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0135
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0065 0.0147 0.0189
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0065 0.0147 0.0189
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Brugia malayi prostaglandin transporter 0.0027 0.0038 0.0049
Brugia malayi SPARC precursor 0.0019 0.0013 0.0017
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0279 0.0358
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0019 0.0101
Schistosoma mansoni rab6-interacting 0.014 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Echinococcus multilocularis serotonin receptor 0.0065 0.0147 0.0147
Brugia malayi ecdysone receptor 0.0051 0.0106 0.0136
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0098 0.024 0.024
Schistosoma mansoni glucose transport protein 0.0014 0.0001 0.0001
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0398 0.1101 0.5472
Schistosoma mansoni pyruvate kinase 0.0035 0.0059 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0075 0.0397
Trypanosoma cruzi p450 reductase, putative 0.0026 0.0035 0.0183
Echinococcus granulosus histone deacetylase 3 0.0398 0.1101 0.1101
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0037 0.0064 0.0339
Onchocerca volvulus 0.0111 0.0279 0.0357
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0279 0.0279
Brugia malayi cytoplasmic intermediate filament protein 0.0059 0.0129 0.0166
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Echinococcus granulosus neuropeptides capa receptor 0.0065 0.0147 0.0147
Trypanosoma cruzi aldo-keto reductase 0.0111 0.0279 0.1477
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Echinococcus granulosus neuropeptides capa receptor 0.0065 0.0147 0.0147
Brugia malayi hypothetical protein 0.0026 0.0033 0.0042
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0121 0.0641
Echinococcus multilocularis pyruvate kinase 0.0027 0.0038 0.0038
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0008 0.0058
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0108 0.027 0.0347
Trypanosoma brucei glucose transporter, putative 0.0014 0.0001 0.0003
Echinococcus granulosus follistatin 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0034 0.0044
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.0059 0.0076
Giardia lamblia Aldose reductase 0.0111 0.0279 0.206
Trichomonas vaginalis histone deacetylase, putative 0.0398 0.1101 0.5472
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Echinococcus granulosus pyruvate kinase 0.0018 0.001 0.001
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0101 0.013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0147 0.0147
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0212 0.0212
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0061 0.0318
Trypanosoma brucei glucose transporter, putative 0.0014 0.0001 0.0003
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0194 0.0515 0.0662
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0101 0.0101
Schistosoma mansoni sugar transporter 0.0014 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0462 0.2297
Onchocerca volvulus 0.0065 0.0147 0.0188
Onchocerca volvulus 0.0065 0.0147 0.0188
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0065 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Loa Loa (eye worm) hypothetical protein 0.0398 0.1101 0.1414
Mycobacterium leprae Conserved hypothetical protein 0.0066 0.0149 0.2999
Onchocerca volvulus 0.0045 0.0089 0.0113
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0105 0.0519
Echinococcus granulosus histone deacetylase 7 0.0143 0.0368 0.0368
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0108 0.027 0.0347
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0045 0.0089 0.0799
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0033 0.0172
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0221 0.0221
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0121 0.0599
Plasmodium falciparum glutathione reductase 0.005 0.0101 0.0915
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0437 0.2169
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0514 0.2724
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0108 0.027 0.0347
Brugia malayi putative neuropeptide receptor 0.0065 0.0147 0.0189
Onchocerca volvulus 0.0027 0.0038 0.0048
Loa Loa (eye worm) G-protein coupled receptor 0.0065 0.0147 0.0189
Loa Loa (eye worm) hypothetical protein 0.0108 0.027 0.0347
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0235 0.0301
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0783 0.389
Echinococcus multilocularis solute carrier family 22 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0034 0.0057 0.0073
Onchocerca volvulus 0.0065 0.0147 0.0188
Brugia malayi Sugar transporter family protein 0.0014 0.0001 0.0001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0181 0.0181
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0014 0.0001 0.0001
Trichomonas vaginalis histone deacetylase, putative 0.0398 0.1101 0.5472
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0113 0.0283 0.1501
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Echinococcus granulosus ecdysone induced protein 78C 0.0108 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0057 0.0124 0.0159
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0075 0.0397
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0002 0.0003
Brugia malayi hypothetical protein 0.0057 0.0124 0.0159
Entamoeba histolytica hypothetical protein 0.0049 0.0099 0.0898
Schistosoma mansoni hypothetical protein 0.0346 0.0953 0.0953
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0028 0.0134
Plasmodium vivax SET domain protein, putative 0.0091 0.0221 0.2004
Brugia malayi RE15519p 0.0065 0.0147 0.0189
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0065 0.0147 0.0147
Schistosoma mansoni follistatin 0.0019 0.0013 0.0013
Brugia malayi nuclear receptor NHR-88 0.0108 0.027 0.0347
Echinococcus granulosus neurogenic locus notch protein 0.0485 0.1351 0.1351
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0105 0.0519
Schistosoma mansoni potassium channel beta 0.0045 0.0089 0.0089
Brugia malayi histone deacetylase 11 0.0143 0.0368 0.0473
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Echinococcus multilocularis neurogenic locus notch protein 0.0485 0.1351 0.1351
Echinococcus granulosus intermediate filament protein 0.011 0.0276 0.0276
Echinococcus multilocularis cysteine protease 0.0051 0.0105 0.0105
Echinococcus granulosus tm gpcr rhodopsin 0.0065 0.0147 0.0147
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.007 0.0372
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0001 0.0001
Brugia malayi photoreceptor-specific nuclear receptor 0.0108 0.027 0.0347
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0094
Entamoeba histolytica alcohol dehydrogenase, putative 0.0045 0.0089 0.0804
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0057 0.0279
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0086 0.011
Toxoplasma gondii histone deacetylase HDAC1 0.0143 0.0368 0.2725
Loa Loa (eye worm) oxidoreductase 0.0111 0.0279 0.0358
Onchocerca volvulus 0.0065 0.0147 0.0188
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0001 0.0001
Schistosoma mansoni neuropeptide F-like receptor 0.0065 0.0147 0.0147
Echinococcus granulosus geminin 0.0346 0.0953 0.0953
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0045 0.0089 0.0651
Schistosoma mansoni hypothetical protein 0.0485 0.1351 0.1351
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0057 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0053 0.0263
Schistosoma mansoni laminin gamma-3 chain 0.0485 0.1351 0.1351
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0065 0.0147 0.0147
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0026 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0485 0.1351 0.1351
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0108 0.027 0.027
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0051 0.0106 0.0106
Brugia malayi ecdysteroid receptor 0.0108 0.027 0.0347
Loa Loa (eye worm) hypothetical protein 0.0108 0.027 0.0347
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0279 0.0279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0041 0.0203
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0189 0.0501 0.2655
Echinococcus granulosus serotonin receptor 0.0065 0.0147 0.0147
Schistosoma mansoni tyrosine kinase 0.0078 0.0183 0.0183
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0034 0.0034
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0053 0.0112 0.0112
Onchocerca volvulus 0.2727 0.7781 1
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0514 0.2724
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0051 0.0106 0.0135
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0082 0.0403
Echinococcus multilocularis protein jagged 1 0.0485 0.1351 0.1351
Brugia malayi hypothetical protein 0.0077 0.0181 0.0232
Echinococcus multilocularis neuropeptide receptor 0.0065 0.0147 0.0147
Mycobacterium ulcerans hypothetical protein 0.0044 0.0085 0.0445
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0094
Schistosoma mansoni amine GPCR 0.0065 0.0147 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Entamoeba histolytica cysteine protease, putative 0.0026 0.0034 0.0311
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0071 0.0649
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0672 0.1888 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0065 0.0147 0.0147
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0051 0.0106 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0005
Schistosoma mansoni opsin-like receptor 0.0065 0.0147 0.0147
Schistosoma mansoni neuropeptide F-like receptor 0.0065 0.0147 0.0147
Schistosoma mansoni biogenic amine receptor 0.0065 0.0147 0.0147
Brugia malayi Cathepsin L-like precursor 0.0051 0.0105 0.0135
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0108 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0001 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0075 0.0397
Echinococcus granulosus aldo keto reductase 0.0111 0.0279 0.0279
Echinococcus multilocularis thyroid hormone receptor alpha 0.0357 0.0984 0.0984
Mycobacterium ulcerans hypothetical protein 0.0044 0.0085 0.0445
Trichomonas vaginalis histone deacetylase, putative 0.0398 0.1101 0.5472
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0026 0.0035 0.0035
Schistosoma mansoni neuropeptide receptor 0.0065 0.0147 0.0147
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Schistosoma mansoni amine GPCR 0.0065 0.0147 0.0147
Echinococcus granulosus epidermal growth factor receptor 0.0079 0.0185 0.0185
Loa Loa (eye worm) 4-hydroxyphenylpyruvate dioxygenase 0.0044 0.0085 0.0109
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Brugia malayi Cadherin domain containing protein 0.0485 0.1351 0.1736
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0108 0.027 0.027
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0087 0.0208 0.0208
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0173 0.0456 0.0456
Brugia malayi histone deacetylase 3 (HD3) 0.0398 0.1101 0.1414
Brugia malayi Cathepsin L-like precursor 0.0051 0.0105 0.0135
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0049
Brugia malayi hypothetical protein 0.0065 0.0147 0.0189
Echinococcus granulosus histone deacetylase 6 0.0143 0.0368 0.0368
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.006
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0003 0.0018
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0279 0.0358
Schistosoma mansoni slit 0.0485 0.1351 0.1351
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0037 0.0064 0.0339
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0034 0.0181
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Echinococcus multilocularis g-protein coupled receptor 0.0065 0.0147 0.0147
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.007 0.0346
Echinococcus granulosus solute carrier family 22 0.0014 0.0001 0.0001
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0008 0.0042
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0051 0.0105 0.0948
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0049
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0009
Onchocerca volvulus Neurogenic locus notch homolog 0.0485 0.1351 0.1735
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0121 0.0155
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0037 0.0064 0.0335
Echinococcus granulosus neuropeptide s receptor 0.1956 0.5569 0.5569
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0279 0.1384
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0014 0.0001 0.0001
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.0059 0.0433
Echinococcus multilocularis solute carrier family 22 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Schistosoma mansoni hypothetical protein 0.0096 0.0235 0.0235
Schistosoma mansoni biogenic amine (5HT) receptor 0.0065 0.0147 0.0147
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0514 0.2724
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0121 0.1453
Brugia malayi Cytochrome P450 family protein 0.0046 0.009 0.0116
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0017
Trypanosoma cruzi cruzipain precursor, putative 0.0193 0.0514 0.2724
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0783 0.389
Brugia malayi follicle stimulating hormone receptor 0.0065 0.0147 0.0189
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0105 0.0519
Echinococcus multilocularis G protein coupled receptor 139 0.0065 0.0147 0.0147
Leishmania major pyruvate kinase 0.0035 0.0059 0.0313
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0485 0.1351 0.1736
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0001 0.0001
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0065 0.0147 0.0189
Echinococcus multilocularis insulin receptor 0.0047 0.0093 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Echinococcus multilocularis g protein coupled receptor 0.0065 0.0147 0.0147
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0034 0.0311
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0003 0.0003
Echinococcus granulosus allatostatin A receptor 0.0065 0.0147 0.0147
Leishmania major cathepsin L-like protease 0.0051 0.0105 0.0556
Schistosoma mansoni fatty acid binding protein 0.0034 0.0056 0.0056
Leishmania major p450 reductase, putative 0.0026 0.0035 0.0183
Loa Loa (eye worm) hypothetical protein 0.0192 0.0511 0.0657
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0045 0.0089 0.0437
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0013 0.0091
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0221 0.0221
Echinococcus multilocularis neuropeptide receptor 0.0065 0.0147 0.0147
Echinococcus multilocularis dna polymerase kappa 0.004 0.0075 0.0075
Brugia malayi Calcitonin receptor-like protein seb-1 0.0309 0.0846 0.1088
Echinococcus granulosus neurogenic locus notch protein 4 0.0485 0.1351 0.1351
Entamoeba histolytica cysteine protease, putative 0.0026 0.0034 0.0311
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0053 0.0112 0.0112
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0309 0.0846 0.1088
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.0212 0.0212
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.0059 0.0014
Echinococcus granulosus agrin 0.0019 0.0013 0.0013
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0098 0.024 0.024
Brugia malayi nuclear receptor NHR-88 0.0051 0.0106 0.0136
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Trypanosoma brucei glucose transporter, putative 0.0014 0.0001 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0105 0.0519
Echinococcus granulosus insulin receptor 0.0047 0.0093 0.0093
Schistosoma mansoni glucose transporter 0.0014 0.0001 0.0001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0194 0.0515 0.0662
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0135 0.0135
Schistosoma mansoni tyrosine kinase 0.0047 0.0093 0.0093
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0091 0.0221 0.0221
Schistosoma mansoni neuropeptide receptor 0.0065 0.0147 0.0147
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0148 0.0384 0.0384
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0108 0.027 0.0347
Loa Loa (eye worm) G-protein coupled receptor 0.0065 0.0147 0.0189
Echinococcus granulosus nuclear receptor nhr 48 0.0051 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Onchocerca volvulus Peroxidasin homolog 0.2727 0.7781 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0009
Echinococcus granulosus epidermal growth factor receptor 0.0146 0.0379 0.0379
Loa Loa (eye worm) DR-78 0.0051 0.0106 0.0136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0514 0.2724
Echinococcus granulosus histone deacetylase 6 0.0143 0.0368 0.0368
Brugia malayi flavodoxin family protein 0.0026 0.0035 0.0044
Echinococcus granulosus aldo keto reductase 0.0111 0.0279 0.0279
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0084 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0108 0.027 0.0347
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0065 0.0147 0.0147
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0161 0.042 0.2223
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0051 0.0106 0.0136
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0057 0.0279
Schistosoma mansoni hypothetical protein 0.0065 0.0147 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Plasmodium vivax histone deacetylase, putative 0.0143 0.0368 0.3344
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0147
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0279 0.1384
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0002 0.0002
Leishmania major aldo-keto reductase-like protein 0.0111 0.0279 0.1477
Schistosoma mansoni hypothetical protein 0.0065 0.0147 0.0147
Giardia lamblia GTOR 0.0044 0.0086 0.0631
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Brugia malayi lactoylglutathione lyase 0.0189 0.0501 0.0644
Loa Loa (eye worm) hypothetical protein 0.0057 0.0124 0.0159
Loa Loa (eye worm) hypothetical protein 0.0026 0.0035 0.0044
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0086 0.078
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0279 0.1384
Onchocerca volvulus 0.0065 0.0147 0.0188
Brugia malayi dehydrogenases, short chain protein 2 0.0044 0.0084 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0028 0.0134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0034 0.0181
Loa Loa (eye worm) hypothetical protein 0.0026 0.0033 0.0042
Echinococcus granulosus protein jagged 2 0.0485 0.1351 0.1351
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0101 0.0537
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0026 0.0035 0.0183
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0135 0.0135
Plasmodium vivax vivapain-3 0.0026 0.0034 0.0306
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0147 0.0147
Leishmania major protein kinase, putative 0.0017 0.0007 0.0036
Echinococcus multilocularis histone deacetylase 8 0.0143 0.0368 0.0368
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0086 0.0455
Mycobacterium tuberculosis Probable oxidoreductase 0.0126 0.032 0.1693
Onchocerca volvulus 0.014 0.0362 0.0465
Brugia malayi Cytochrome P450 family protein 0.0075 0.0175 0.0225
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0034 0.0181
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0126 0.032 0.8615
Loa Loa (eye worm) hypothetical protein 0.0057 0.0124 0.0159
Schistosoma mansoni alpha-1 adrenergic receptor 0.0065 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Trichomonas vaginalis aldo/keto reductase, putative 0.0111 0.0279 0.1384
Onchocerca volvulus 0.0485 0.1351 0.1735
Mycobacterium tuberculosis Conserved protein TB27.3 0.0044 0.0085 0.0448
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0002 0.0002
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0079 0.0185 0.0185
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0065 0.0147 0.0147
Plasmodium vivax histone deacetylase 2, putative 0.0143 0.0368 0.3344
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Echinococcus multilocularis g protein coupled receptor 0.0065 0.0147 0.0147
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0105 0.0105
Onchocerca volvulus 0.0065 0.0147 0.0188
Echinococcus multilocularis expressed protein 0.0019 0.0013 0.0013
Echinococcus granulosus pyruvate kinase 0.0018 0.001 0.001
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0111 0.0279 0.1477
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Schistosoma mansoni hypothetical protein 0.0098 0.024 0.024
Plasmodium vivax histone deacetylase, putative 0.0143 0.0368 0.3344
Onchocerca volvulus 0.0099 0.0245 0.0313
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0045 0.0089 0.0114
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0105 0.0105
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0398 0.1101 0.5472
Schistosoma mansoni hypothetical protein 0.0427 0.1183 0.1183
Schistosoma mansoni biogenic amine (5HT) receptor 0.0065 0.0147 0.0147
Echinococcus multilocularis survival motor neuron protein 1 0.0471 0.1309 0.1309
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Entamoeba histolytica cysteine protease, putative 0.0026 0.0034 0.0311
Echinococcus multilocularis aldo keto reductase 0.0111 0.0279 0.0279
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.007 0.0516
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0131 0.0168
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Giardia lamblia Pyruvate kinase 0.0018 0.001 0.0073
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0105 0.0134
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0033 0.0236
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0121 0.1094
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0038 0.0038
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0011 0.0011
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0003 0.0021
Schistosoma mansoni retinoic acid receptor RXR 0.0205 0.0548 0.0548
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0008
Echinococcus granulosus death domain containing protein 0.0015 0.0002 0.0002
Echinococcus multilocularis methionine synthase reductase 0.0016 0.0006 0.0006
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0014 0.0001 0.0003
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0309 0.0846 0.1088
Toxoplasma gondii exonuclease III APE 0.0056 0.0121 0.0891
Echinococcus multilocularis pyruvate kinase 0.0035 0.0059 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0005
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0121 1
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0037 0.0064 0.0335
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0105 0.0105
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0437 0.2169
Plasmodium vivax glutathione reductase, putative 0.005 0.0101 0.0915
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0008 0.0058
Brugia malayi M-phase phosphoprotein, mpp8 0.0099 0.0245 0.0314
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0108 0.027 0.0347
Echinococcus granulosus dro:myosuppressin receptor 0.0065 0.0147 0.0147
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0037 0.0064 0.0335
Schistosoma mansoni agrin 0.0019 0.0013 0.0013
Mycobacterium tuberculosis Probable reductase 0.0113 0.0283 0.1501
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0111 0.0279 0.1384
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0194 0.0515 0.0515
Echinococcus granulosus histone deacetylase 8 0.0143 0.0368 0.0368
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0057 0.0124 0.0159
Trichomonas vaginalis histone deacetylase, putative 0.0398 0.1101 0.5472
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0037 0.0064 0.0339
Loa Loa (eye worm) oxidoreductase 0.0111 0.0279 0.0358
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0003 0.0018
Echinococcus multilocularis pyruvate kinase 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0471 0.1309 0.1682
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0033 0.0172
Loa Loa (eye worm) hypothetical protein 0.0053 0.0112 0.0144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0134
Schistosoma mansoni aldo-keto reductase 0.0111 0.0279 0.0279
Onchocerca volvulus Chorion peroxidase homolog 0.2727 0.7781 1
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0034 0.0167
Onchocerca volvulus 0.0715 0.2011 0.2584
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0113 0.0283 0.1501
Onchocerca volvulus 0.0034 0.0057 0.0072
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0065 0.0147 0.0189
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0192 0.0511 0.0656
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.007 0.0638
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0065 0.0147 0.0147
Trypanosoma cruzi cysteine protease, putative 0.0026 0.0034 0.0181
Leishmania major cytochrome p450-like protein 0.0046 0.009 0.0477
Trypanosoma brucei unspecified product 0.0034 0.0056 0.0298
Brugia malayi AKH receptor 0.0065 0.0147 0.0189
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0037 0.0064 0.0335
Trichomonas vaginalis set domain proteins, putative 0.0715 0.2011 1
Mycobacterium tuberculosis Conserved protein 0.0044 0.0085 0.0448
Onchocerca volvulus 0.0051 0.0105 0.0134
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0108 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0075 0.0397
Echinococcus multilocularis orexin receptor type 2 0.0065 0.0147 0.0147
Schistosoma mansoni hypothetical protein 0.0249 0.0673 0.0673
Echinococcus multilocularis fmrfamide receptor 0.0065 0.0147 0.0147
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0437 0.2169
Entamoeba histolytica cysteine protease, putative 0.0026 0.0034 0.0311
Mycobacterium ulcerans epoxide hydrolase EphA 0.0161 0.042 0.2221
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0279 0.0279
Loa Loa (eye worm) inositol-1 0.0039 0.007 0.009
Onchocerca volvulus 0.0051 0.0105 0.0134
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0113 0.0283 0.7421
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.006 0.0295
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0013 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0147 0.0147
Mycobacterium leprae Conserved hypothetical protein 0.0037 0.0064 0.0176
Leishmania major histone deacetylase, putative 0.0398 0.1101 0.5831
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0008 0.0652
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0008 0.0045
Brugia malayi Calcium binding EGF domain containing protein 0.0485 0.1351 0.1736
Loa Loa (eye worm) animal heme peroxidase 0.2727 0.7781 1
Brugia malayi neuropeptide F receptor 0.0065 0.0147 0.0189
Brugia malayi nuclear hormone receptor family member odr-7 0.0051 0.0106 0.0136
Echinococcus multilocularis neuropeptide FF receptor 2 0.0065 0.0147 0.0147
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0008 0.0652
Toxoplasma gondii histone deacetylase HDAC5 0.0143 0.0369 0.2727
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0106 0.0106
Brugia malayi hypothetical protein 0.0027 0.0038 0.0049
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0006 0.0031
Schistosoma mansoni hypothetical protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.011 0.0276 0.0355
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0082 0.06
Giardia lamblia Histone deacetylase 0.0398 0.1101 0.8148
Onchocerca volvulus 0.2727 0.7781 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.0783 0.5793
Echinococcus granulosus cathepsin l cysteine peptidase 0.0051 0.0105 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0037 0.0064 0.0339
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0147
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0049
Brugia malayi nuclear receptor RXR 0.0057 0.0124 0.0159
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0004
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0135 0.0135
Echinococcus multilocularis histone deacetylase 6 0.0143 0.0368 0.0368
Loa Loa (eye worm) hypothetical protein 0.0211 0.0566 0.0727
Echinococcus multilocularis sex peptide receptor 0.0065 0.0147 0.0147
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0194 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0783 0.7111
Brugia malayi Muscle positioning protein 4 0.0485 0.1351 0.1736
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Entamoeba histolytica cysteine protease, putative 0.0026 0.0034 0.0311
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0003 0.0018
Brugia malayi Calcium binding EGF domain containing protein 0.0485 0.1351 0.1736
Brugia malayi Protein kinase domain containing protein 0.0047 0.0093 0.012
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0034 0.0044
Onchocerca volvulus 0.2727 0.7781 1
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0057 0.0057
Loa Loa (eye worm) histone deacetylase 3 0.0398 0.1101 0.1414
Schistosoma mansoni tyrosine kinase 0.0047 0.0093 0.0093
Mycobacterium tuberculosis Conserved protein 0.0045 0.0089 0.0469
Entamoeba histolytica cysteine protease, putative 0.0026 0.0034 0.0311
Echinococcus granulosus lamin dm0 0.011 0.0276 0.0276
Schistosoma mansoni hypothetical protein 0.0211 0.0566 0.0566
Plasmodium falciparum glyoxalase I 0.0189 0.0501 0.4551
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0047 0.0248
Schistosoma mansoni single-minded 0.0048 0.0096 0.0096
Echinococcus multilocularis FTZ F1 alpha 0.0108 0.027 0.027
Giardia lamblia Hypothetical protein 0.0023 0.0026 0.0188
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0111 0.0279 0.1384
Echinococcus granulosus cathepsin L cysteine proteinase 0.0051 0.0105 0.0105
Brugia malayi nuclear hormone receptor 0.0108 0.027 0.0347
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0051 0.0106 0.0106
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.009 0.0477
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Entamoeba histolytica cysteine protease, putative 0.0026 0.0034 0.0311
Mycobacterium ulcerans hypothetical protein 0.0044 0.0085 0.0445
Echinococcus granulosus aldehyde reductase 0.0066 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0026 0.0035 0.0183
Loa Loa (eye worm) hypothetical protein 0.0108 0.027 0.0347
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0026 0.0035 0.0308
Leishmania major cathepsin L-like protease 0.0193 0.0514 0.2724
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0007 0.0039
Brugia malayi hypothetical protein 0.0051 0.0106 0.0136
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0086 0.0086
Schistosoma mansoni tyrosine kinase 0.0078 0.0183 0.0183
Entamoeba histolytica cysteine protease, putative 0.0026 0.0034 0.0311
Onchocerca volvulus Histone deacetylase 10 homolog 0.0143 0.0368 0.0473
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0011 0.0011
Trypanosoma brucei aldo-keto reductase, putative 0.0111 0.0279 0.1477
Brugia malayi neuropeptide F receptor 0.0065 0.0147 0.0189
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Mycobacterium tuberculosis Probable oxidoreductase 0.0111 0.0279 0.1477
Plasmodium falciparum aldo-keto reductase, putative 0.0045 0.0089 0.0799
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0037 0.0064 0.0335
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0105 0.0519
Schistosoma mansoni microtubule-associated protein tau 0.3501 1 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0065 0.0147 0.0147
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0075 0.0397
Toxoplasma gondii histone lysine methyltransferase SET1 0.012 0.0304 0.2248
Echinococcus multilocularis epidermal growth factor receptor 0.0146 0.0379 0.0379
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0121 0.0641
Loa Loa (eye worm) nuclear receptor NHR-67 0.0051 0.0106 0.0136
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0038 0.0048
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0106 0.0106
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0045 0.0089 0.0089
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0687 0.3414
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0047 0.0248
Onchocerca volvulus 0.0111 0.0279 0.0357
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0105 0.0519
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0001 0.0001
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0098 0.024 0.024
Giardia lamblia High cysteine protein 0.0485 0.1351 1
Plasmodium vivax JmjC domain containing protein 0.0015 0.0003 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0005
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0181 0.0181
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0135 0.0173
Echinococcus multilocularis ecdysone induced protein 78C 0.0108 0.027 0.027
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0008 0.0071
Schistosoma mansoni aldo-keto reductase 0.0111 0.0279 0.0279
Schistosoma mansoni sugar transporter 0.0014 0.0001 0.0001
Schistosoma mansoni notch 0.0485 0.1351 0.1351
Echinococcus multilocularis solute carrier family 22 0.0014 0.0001 0.0001
Schistosoma mansoni cell polarity protein 0.0485 0.1351 0.1351
Onchocerca volvulus 0.0065 0.0147 0.0188
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0022 0.0022
Toxoplasma gondii aldo-keto reductase 0.0045 0.0089 0.0651
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0053 0.0263
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0061 0.0078
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Brugia malayi Pre-SET motif family protein 0.0091 0.0221 0.0284
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0057 0.0124 0.0124
Onchocerca volvulus 0.0096 0.0235 0.0301
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0003 0.0003
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0126 0.032 0.1693
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.009 0.0116
Brugia malayi EGF-like domain containing protein 0.0485 0.1351 0.1736
Trypanosoma brucei glucose transporter 2A 0.0014 0.0001 0.0003
Onchocerca volvulus 0.0065 0.0147 0.0188
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0086 0.0455
Entamoeba histolytica hypothetical protein 0.0077 0.0181 0.1642
Loa Loa (eye worm) glutathione reductase 0.005 0.0101 0.013
Brugia malayi jmjC domain containing protein 0.0015 0.0003 0.0004
Echinococcus multilocularis neuropeptides capa receptor 0.0065 0.0147 0.0147
Plasmodium falciparum cysteine proteinase falcipain 1 0.0026 0.0034 0.0306
Brugia malayi polk-prov protein 0.0031 0.0047 0.006
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0086 0.011
Trypanosoma brucei glucose transporter, putative 0.0014 0.0001 0.0003
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0065 0.0147 0.0147
Schistosoma mansoni nuclear receptor nhr-48 0.0051 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0094
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0173 0.0456 0.0586
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0108 0.027 0.027
Brugia malayi Steroid receptor seven-up type 2 0.0108 0.027 0.0347
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0108 0.027 0.0347
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0105 0.0519
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0065 0.0147 0.0147
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0033 0.029
Echinococcus granulosus sex peptide receptor 0.0065 0.0147 0.0147
Loa Loa (eye worm) steroid hormone receptor 0.0108 0.027 0.0347
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0037 0.0064 0.0335
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0075 0.037
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0108 0.027 0.027
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.0124 0.0159
Echinococcus granulosus tm gpcr rhodopsin 0.0065 0.0147 0.0147
Brugia malayi hypothetical protein 0.0065 0.0147 0.0189
Loa Loa (eye worm) hypothetical protein 0.014 0.0362 0.0465
Onchocerca volvulus 0.0051 0.0105 0.0134
Leishmania major glyoxalase I,trypanothione-dependent glyoxalase I 0.0189 0.0501 0.2655
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0014 0.0001 0.0001
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0008 0.0039
Onchocerca volvulus 0.0027 0.0038 0.0048
Echinococcus multilocularis RUN 0.014 0.0362 0.0362
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0002 0.0002
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0012 0.0063
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0279 0.1384
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0014 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0108 0.027 0.0347
Echinococcus granulosus biogenic amine 5HT receptor 0.0065 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0037 0.0064 0.0339
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0037 0.0064 0.0335
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0514 0.2724
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0001 0.0001
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0121 0.1094
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0008 0.0071
Loa Loa (eye worm) neuropeptide F receptor 0.0065 0.0147 0.0189
Onchocerca volvulus 0.0111 0.0279 0.0357
Schistosoma mansoni opsin-like receptor 0.0065 0.0147 0.0147
Trypanosoma cruzi histone deacetylase, putative 0.0143 0.0368 0.1952
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.0212 0.0212
Echinococcus granulosus cpg binding protein 0.0063 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Leishmania major cysteine peptidase A (CPA) 0.0051 0.0105 0.0556
Entamoeba histolytica cysteine protease, putative 0.0026 0.0034 0.0311
Brugia malayi nuclear hormone receptor 0.0051 0.0106 0.0136
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0037 0.0064 0.0339
Brugia malayi Cytochrome P450 family protein 0.0046 0.009 0.0116
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0065 0.0147 0.0147
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0003 0.0021
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0051 0.0105 0.0948
Onchocerca volvulus 0.0051 0.0106 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0134
Brugia malayi cytochrome P450 0.0037 0.0064 0.0082
Onchocerca volvulus 0.0111 0.0279 0.0357
Schistosoma mansoni tyrosine kinase 0.0078 0.0183 0.0183
Echinococcus multilocularis microtubule associated protein 2 0.3501 1 1
Entamoeba histolytica cysteine protease, putative 0.0026 0.0034 0.0311
Brugia malayi hypothetical protein 0.0065 0.0147 0.0189
Onchocerca volvulus Putative protein 0.0044 0.0085 0.0108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0514 0.2724
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0034 0.0167
Leishmania major cytochrome P450 reductase, putative 0.0023 0.0026 0.0138
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0008 0.0045
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0125 0.0125
Leishmania major phosphopantetheinyl transferase-like protein 0.0049 0.0099 0.0524
Echinococcus multilocularis follistatin 0.0019 0.0013 0.0013
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0108 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0009
Echinococcus granulosus peroxidasin 0.2727 0.7781 0.7781
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0687 0.3414
Entamoeba histolytica cysteine protease, putative 0.0051 0.0105 0.0953
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0038 0.02
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0067 0.0332
Brugia malayi Nuclear hormone receptor E75 0.0051 0.0106 0.0136
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0279 0.0358
Brugia malayi Cathepsin L-like precursor 0.0051 0.0105 0.0135
Plasmodium vivax pyruvate kinase, putative 0.0035 0.0059 0.0531
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0108 0.027 0.0346
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0075 0.0397
Echinococcus multilocularis aldo keto reductase 0.0111 0.0279 0.0279
Trichomonas vaginalis aldo-keto reductase, putative 0.0045 0.0089 0.0437
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0181 0.0181
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.006 0.0318
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0026 0.0035 0.0183
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.084 0.237 0.237
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0056 0.0298
Toxoplasma gondii cytochrome p450 superfamily protein 0.0037 0.0064 0.0469
Echinococcus granulosus neuropeptide Y receptor 0.0065 0.0147 0.0147
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0121 0.0155
Onchocerca volvulus 0.0102 0.0253 0.0325
Loa Loa (eye worm) hypothetical protein 0.0034 0.0057 0.0073
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0034 0.0311
Brugia malayi Cathepsin L-like precursor 0.0051 0.0105 0.0135
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0037 0.0064 0.0339
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0037 0.0064 0.0335
Schistosoma mansoni hypothetical protein 0.0485 0.1351 0.1351
Brugia malayi Thioredoxin reductase 0.005 0.0101 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0058
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0111 0.0279 0.7268
Leishmania major glucose transporter, lmgt3 0.0014 0.0001 0.0003
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0071 0.0525
Echinococcus multilocularis fat cadherin tumor suppressor 0.0485 0.1351 0.1351
Echinococcus multilocularis pyruvate kinase 0.0018 0.001 0.001
Schistosoma mansoni neuropeptide receptor 0.0065 0.0147 0.0147
Mycobacterium ulcerans biphenyl-2,3-diol 1,2-dioxygenase 0.0044 0.0085 0.0445
Echinococcus granulosus solute carrier family 22 0.0014 0.0001 0.0001
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0047 0.0093 0.0093
Echinococcus multilocularis histone deacetylase 3 0.0398 0.1101 0.1101
Toxoplasma gondii protease inhibitor PI2 0.0019 0.0013 0.0091
Leishmania major glucose transporter, lmgt1 0.0014 0.0001 0.0003
Loa Loa (eye worm) animal heme peroxidase 0.2727 0.7781 1
Onchocerca volvulus 0.0035 0.0061 0.0077
Brugia malayi jmjC domain containing protein 0.0061 0.0135 0.0173
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0019 0.0098
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0309 0.0846 0.1088
Echinococcus granulosus fatty acid binding protein FABP2 0.0034 0.0056 0.0056
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0008 0.0045
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0061 0.0061
Brugia malayi sulfakinin receptor protein 0.0065 0.0147 0.0189
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0065 0.0147 0.0147
Mycobacterium tuberculosis Probable dehydrogenase 0.0113 0.0283 0.1501
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0065 0.0147 0.0147
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0075 0.0397
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0014 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0037 0.0064 0.0335
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0049 0.0099 0.1167
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0075 0.0397
Loa Loa (eye worm) animal heme peroxidase 0.2727 0.7781 1
Brugia malayi EGF-like domain containing protein 0.0485 0.1351 0.1736
Echinococcus multilocularis allatostatin A receptor 0.0065 0.0147 0.0147
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0099 0.0893
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0147 0.0147
Brugia malayi putative neuropeptide receptor NPR1 0.0065 0.0147 0.0189
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.007 0.0369
Schistosoma mansoni hypothetical protein 0.0098 0.024 0.024
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0177 0.0466 0.2469
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0121 0.0599
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0003 0.0003
Brugia malayi Delta serrate ligand family protein 0.0485 0.1351 0.1736
Echinococcus granulosus slit 2 protein 0.0485 0.1351 0.1351
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0672 0.1888 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0013 0.0013
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0121 0.0641
Schistosoma mansoni cathepsin s 0.0017 0.0007 0.0007
Echinococcus multilocularis 0.0037 0.0064 0.0064
Schistosoma mansoni steroid hormone receptor ad4bp 0.0108 0.027 0.027
Giardia lamblia Aldose reductase 0.0111 0.0279 0.206
Brugia malayi Cytochrome P450 family protein 0.0037 0.0064 0.0082
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0049
Echinococcus granulosus histone deacetylase 0.0143 0.0368 0.0368
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0075 0.0394
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0037 0.0064 0.0339
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.006 0.0318
Echinococcus multilocularis histone deacetylase 6 0.0143 0.0368 0.0368
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0045
Brugia malayi hypothetical protein 0.2727 0.7781 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0279 0.1384
Onchocerca volvulus Bile acid receptor homolog 0.0108 0.027 0.0346
Brugia malayi Blistered cuticle protein 3 0.2727 0.7781 1
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0026 0.0035 0.0183
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Loa Loa (eye worm) TK/INSR protein kinase 0.0047 0.0093 0.012
Echinococcus multilocularis pyruvate kinase 0.0018 0.001 0.001
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0038 0.0049
Loa Loa (eye worm) cysteine protease 0.0051 0.0105 0.0135
Schistosoma mansoni amine GPCR 0.0065 0.0147 0.0147
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0003 0.0004
Entamoeba histolytica hypothetical protein 0.0077 0.0181 0.1642
Trypanosoma cruzi aldo/keto reductase, putative 0.0045 0.0089 0.0469
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Echinococcus multilocularis histone deacetylase 7 0.0143 0.0368 0.0368
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0147
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0672 0.1888 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0049
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0013 0.0091
Brugia malayi Dopamine receptor protein 1 0.0065 0.0147 0.0189
Toxoplasma gondii aldose reductase, putative 0.0111 0.0279 0.206
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0147 0.0147
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0011 0.0011
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0014 0.0001 0.0001
Loa Loa (eye worm) intermediate filament protein 0.011 0.0276 0.0355
Echinococcus multilocularis peroxidasin 0.2727 0.7781 0.7781
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0034 0.0167
Schistosoma mansoni lipoxygenase 0.0587 0.1644 0.1644
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0672 0.1888 1
Echinococcus granulosus pyruvate kinase 0.0018 0.001 0.001
Echinococcus multilocularis fibropellin Ia 0.0485 0.1351 0.1351
Onchocerca volvulus 0.0051 0.0105 0.0134
Echinococcus multilocularis neuropeptides capa receptor 0.0065 0.0147 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0134
Schistosoma mansoni sugar transporter 0.0014 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0044 0.0085 0.0445
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0013 0.0017
Loa Loa (eye worm) nuclear hormone receptor 0.0051 0.0106 0.0136
Schistosoma mansoni cpg binding protein 0.0063 0.0141 0.0141
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.0013 0.0017
Plasmodium falciparum histone deacetylase 1 0.0398 0.1101 1
Schistosoma mansoni coup transcription factor 0.0108 0.027 0.027
Trypanosoma cruzi aldo/keto reductase, putative 0.0111 0.0279 0.1477
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0361 0.1912
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0057 0.0124 0.0124
Echinococcus multilocularis fmrfamide receptor 0.0065 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Echinococcus granulosus cytochrome P450 2K1 0.0037 0.0064 0.0064
Loa Loa (eye worm) acetyltransferase 0.0145 0.0375 0.0483
Loa Loa (eye worm) hypothetical protein 0.0034 0.0057 0.0073
Brugia malayi jmjC domain containing protein 0.0015 0.0003 0.0004
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0026 0.0034 0.0181
Toxoplasma gondii EGF family domain-containing protein 0.0485 0.1351 1
Entamoeba histolytica aldose reductase, putative 0.0111 0.0279 0.2532
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0011 0.0011
Brugia malayi nuclear hormone receptor family member nhr-6 0.0051 0.0106 0.0136
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0147 0.0147
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0013 0.0017
Echinococcus multilocularis somatostatin receptor 0.0065 0.0147 0.0147
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0113 0.0283 0.1501
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0687 0.3414
Brugia malayi G protein-coupled receptor F59B2.13 0.0065 0.0147 0.0189
Echinococcus granulosus g protein coupled receptor 0.0065 0.0147 0.0147
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0037 0.0064 0.0339
Trichomonas vaginalis aldo-keto reductase, putative 0.0045 0.0089 0.0437
Echinococcus granulosus GPCR family 2 0.0098 0.024 0.024
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0065 0.0147 0.0189
Schistosoma mansoni inositol monophosphatase 0.0039 0.007 0.007
Echinococcus granulosus Nuclear hormone receptor HR96 0.0051 0.0106 0.0106
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0037 0.0064 0.0339
Schistosoma mansoni peroxidasin 0.2727 0.7781 0.7781
Onchocerca volvulus Neuropeptide F receptor homolog 0.0065 0.0147 0.0188
Trypanosoma brucei trypanothione reductase 0.005 0.0101 0.0537
Brugia malayi hypothetical protein 0.0065 0.0147 0.0189
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0008 0.0058
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0034 0.0034
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0051 0.0106 0.0106
Schistosoma mansoni organic anion transporter 0.0027 0.0038 0.0038
Onchocerca volvulus 0.0044 0.0084 0.0108
Brugia malayi NADH-dependent xylose reductase 0.0045 0.0089 0.0114
Loa Loa (eye worm) hypothetical protein 0.0108 0.027 0.0347
Loa Loa (eye worm) FAD binding domain-containing protein 0.0016 0.0006 0.0007
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0106 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0086 0.0424
Loa Loa (eye worm) hypothetical protein 0.0057 0.0124 0.0159
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Brugia malayi hypothetical protein 0.0017 0.0007 0.0008
Brugia malayi Uncoordinated protein 44 0.0015 0.0002 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0687 0.3414
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0137
Brugia malayi hypothetical protein 0.0065 0.0147 0.0189
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.0437 0.056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.006 0.0318
Entamoeba histolytica histone deacetylase, putative 0.0398 0.1101 1
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0108 0.027 0.0347
Onchocerca volvulus Putative cubilin 0.0485 0.1351 0.1735
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0026 0.0035 0.018
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0016 0.0006 0.0006
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0057 0.0124 0.0124
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.007 0.0372
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0065 0.0147 0.0147
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0098 0.024 0.024
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0001 0.0003
Trypanosoma brucei glucose transporter, putative 0.0014 0.0001 0.0003
Leishmania major cytochrome p450-like protein 0.0037 0.0064 0.0339
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0059 0.0313
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0045 0.0089 0.0114
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0037 0.0064 0.0339
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Echinococcus granulosus biogenic amine 5HT receptor 0.0065 0.0147 0.0147
Schistosoma mansoni neuropeptide receptor 0.0065 0.0147 0.0147
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Leishmania major hypothetical protein, conserved 0.0014 0.0001 0.0003
Trypanosoma brucei histone deacetylase 4 0.0143 0.0368 0.1952
Loa Loa (eye worm) hypothetical protein 0.016 0.0419 0.0538
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0033 0.0172
Schistosoma mansoni notch 0.0485 0.1351 0.1351
Mycobacterium leprae Possible oxidoreductase 0.0045 0.0089 0.0989
Brugia malayi 4-hydroxyphenylpyruvate dioxygenase family protein 0.0044 0.0085 0.0109
Loa Loa (eye worm) sugar transporter 0.0014 0.0001 0.0001
Schistosoma mansoni peroxidasin 0.2727 0.7781 0.7781
Toxoplasma gondii transporter, major facilitator family protein 0.0027 0.0038 0.0275
Echinococcus multilocularis dro:myosuppressin receptor 0.0065 0.0147 0.0147
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0014 0.0001 0.0001
Plasmodium falciparum glyoxalase I 0.0044 0.0085 0.0764
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Brugia malayi histone deacetylase 1 (HD1) 0.0398 0.1101 0.1414
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0002 0.0003
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0075 0.037
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0485 0.1351 0.1351
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0086 0.0455
Echinococcus multilocularis neurogenic locus notch protein 4 0.0485 0.1351 0.1351
Toxoplasma gondii thioredoxin reductase 0.005 0.0101 0.0746
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Schistosoma mansoni notch 0.0485 0.1351 0.1351
Onchocerca volvulus Peroxidasin homolog 0.2727 0.7781 1
Leishmania major DNA polymerase kappa, putative 0.0021 0.0019 0.0098
Leishmania major histone deacetylase, putative 0.0143 0.0368 0.1952
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.006 0.0295
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Brugia malayi hypothetical protein 0.0027 0.0038 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Brugia malayi Inositol-1 0.0039 0.007 0.009
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0049 0.0099 0.052
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0126 0.032 0.1693
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0038 0.0049
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0045
Leishmania major cathepsin L-like protease 0.0051 0.0105 0.0556
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0037 0.0064 0.0335
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0008 0.0045
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.003 0.0147
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Loa Loa (eye worm) hypothetical protein 0.0108 0.027 0.0347
Schistosoma mansoni thyroid hormone receptor 0.0357 0.0984 0.0984
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0111 0.0279 0.1384
Echinococcus multilocularis musashi 0.011 0.0276 0.0276
Toxoplasma gondii histone deacetylase HDAC3 0.0398 0.1101 0.8148
Schistosoma mansoni hypothetical protein 0.0485 0.1351 0.1351
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0022 0.0022
Schistosoma mansoni rab6-interacting 0.014 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0108 0.027 0.0347
Loa Loa (eye worm) oxidoreductase 0.0111 0.0279 0.0358
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0003 0.0003
Trypanosoma cruzi histone deacetylase, putative 0.0143 0.0368 0.1952
Brugia malayi Dopamine receptor 0.0065 0.0147 0.0189
Trypanosoma brucei pyruvate kinase 1 0.0035 0.0059 0.0313
Brugia malayi Cathepsin L-like precursor 0.0051 0.0105 0.0135
Brugia malayi jmjC domain containing protein 0.0015 0.0003 0.0004
Mycobacterium leprae conserved hypothetical protein 0.0044 0.0085 0.0861
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0254 0.0687 0.0883
Mycobacterium leprae conserved hypothetical protein 0.0049 0.0099 0.1329
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0279 0.0279
Onchocerca volvulus 0.0065 0.0147 0.0188
Echinococcus granulosus orexin receptor type 2 0.0065 0.0147 0.0147
Schistosoma mansoni survival motor neuron protein 0.0096 0.0235 0.0235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0035 0.017
Entamoeba histolytica cysteine protease, putative 0.0026 0.0034 0.0311
Loa Loa (eye worm) fibroinase 0.0051 0.0105 0.0135
Entamoeba histolytica cysteine protease, putative 0.0026 0.0034 0.0311
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0065 0.0147 0.0188
Toxoplasma gondii histone deacetylase HDAC2 0.0398 0.1101 0.8148
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0001 0.0001
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0013 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0108 0.027 0.0347
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0037 0.0064 0.0339
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0075 0.0397
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0105 0.0519
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0364 0.0364
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0279 0.0279
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0007 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Trypanosoma cruzi histone deacetylase 1, putative 0.0398 0.1101 0.5831
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Schistosoma mansoni notch 0.0485 0.1351 0.1351
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0065 0.0147 0.0147
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0194 0.0515 0.0515
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0249 0.0673 0.0673
Toxoplasma gondii histone deacetylase HDAC4 0.0143 0.0368 0.2725
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0783 0.7111
Entamoeba histolytica cysteine proteinase 1, putative 0.0026 0.0034 0.0311
Echinococcus multilocularis protein jagged 1 0.0485 0.1351 0.1351
Brugia malayi notch-like transmembrane receptor 0.0485 0.1351 0.1736
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0279 0.0279
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0051 0.0105 0.0135
Echinococcus granulosus neurogenic locus protein delta 0.0485 0.1351 0.1351
Plasmodium falciparum histone deacetylase 2 0.0143 0.0368 0.3344
Echinococcus multilocularis aldehyde reductase 0.0066 0.0149 0.0149
Mycobacterium tuberculosis Cadmium inducible protein CadI 0.0044 0.0085 0.0448
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0022 0.0028
Onchocerca volvulus 0.0111 0.0279 0.0357
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0037 0.0064 0.0339
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0002 0.0002
Onchocerca volvulus 0.011 0.0276 0.0354
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0045
Chlamydia trachomatis pyruvate kinase 0.0035 0.0059 0.5724
Schistosoma mansoni cpg binding protein 0.006 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Plasmodium vivax vivapain-2 0.0051 0.0105 0.0948
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0086 0.0086
Brugia malayi hypothetical protein 0.0014 0.0001 0.0001
Brugia malayi GnHR receptor homolog 0.0065 0.0147 0.0189
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0065 0.0147 0.0147
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0049 0.0099 0.0728
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0279 0.1384
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0037 0.0064 0.0335
Schistosoma mansoni histone deacetylase 4 5 0.0143 0.0368 0.0368
Schistosoma mansoni notch 0.0485 0.1351 0.1351
Onchocerca volvulus Peroxidase homolog 0.2727 0.7781 1
Echinococcus granulosus g-protein coupled receptor 0.0065 0.0147 0.0147
Schistosoma mansoni 4-hydroxyphenylpyruvate dioxygenase 0.0044 0.0085 0.0085
Trypanosoma brucei prostaglandin f synthase 0.0111 0.0279 0.1477
Brugia malayi PAS domain containing protein 0.0048 0.0096 0.0124
Echinococcus granulosus neuropeptide receptor 0.0065 0.0147 0.0147
Loa Loa (eye worm) Notch2 0.0485 0.1351 0.1736
Onchocerca volvulus 0.0065 0.0147 0.0188
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0084 0.062
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0037 0.0064 0.0339
Schistosoma mansoni inositol monophosphatase 0.0039 0.007 0.007
Brugia malayi hypothetical protein 0.0471 0.1309 0.1682
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0783 0.389
Loa Loa (eye worm) latrophilin receptor protein 2 0.0098 0.024 0.0308
Echinococcus multilocularis neuropeptide receptor A26 0.1956 0.5569 0.5569
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0003 0.0025
Echinococcus multilocularis slit 2 protein 0.0485 0.1351 0.1351
Schistosoma mansoni lamin 0.011 0.0276 0.0276
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0514 0.2724
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0034 0.0311
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0002 0.0002
Brugia malayi latrophilin 2 splice variant baaae 0.0211 0.0566 0.0727
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0514 0.2724
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0026 0.0035 0.0035
Trypanosoma brucei sugar transporter, putative 0.0014 0.0001 0.0003
Echinococcus multilocularis Ankyrin 0.0015 0.0003 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Echinococcus multilocularis solute carrier family 22 0.0014 0.0001 0.0001
Brugia malayi GCC2 and GCC3 family protein 0.0485 0.1351 0.1736
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0086 0.0424
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0279 0.0279
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0085 0.0418
Brugia malayi Peroxidasin 0.2727 0.7781 1
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0001 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Trypanosoma brucei THT1 - hexose transporter, putative 0.0014 0.0001 0.0003
Echinococcus granulosus cathepsin l1 0.0034 0.0057 0.0057
Echinococcus granulosus histone lysine methyltransferase setb 0.0091 0.0221 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Echinococcus multilocularis aldo keto reductase 0.0111 0.0279 0.0279
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0111 0.0279 0.1477
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0279 0.0279
Loa Loa (eye worm) melatonin receptor type 1A 0.0065 0.0147 0.0189
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0049 0.0099 1
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0037 0.0064 0.0335
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0105 0.0105
Echinococcus multilocularis Polycystic kidney disease protein 0.014 0.0362 0.0362
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0279 0.0279
Onchocerca volvulus 0.0051 0.0106 0.0135
Leishmania major glucose transporter/membrane transporter D2, putative 0.0014 0.0001 0.0003
Trypanosoma brucei histone deacetylase 2 0.0143 0.0368 0.1952
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Loa Loa (eye worm) hypothetical protein 0.0143 0.0368 0.0473
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0783 0.389
Leishmania major prostaglandin f synthase, putative 0.0111 0.0279 0.1477
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0221 0.0221
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.001 0.0089
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0108 0.027 0.027
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0121 0.0638
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0279 0.0279
Mycobacterium ulcerans hypothetical protein 0.0045 0.0089 0.0466
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0279 0.0279
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Echinococcus granulosus pyruvate kinase 0.0035 0.0059 0.0059
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Echinococcus multilocularis geminin 0.0346 0.0953 0.0953
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3444 0.9838 0.9838
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0001 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0065 0.0147 0.0147
Schistosoma mansoni netrin receptor unc5 0.0015 0.0002 0.0002
Echinococcus granulosus Nuclear hormone receptor HR96 0.0051 0.0106 0.0106
Brugia malayi Pre-SET motif family protein 0.0629 0.1762 0.2265
Schistosoma mansoni lipoxygenase 0.084 0.237 0.237
Plasmodium vivax glyoxalase I, putative 0.0189 0.0501 0.4551
Echinococcus multilocularis pyruvate kinase 0.0035 0.0059 0.0059
Trypanosoma cruzi major cysteine proteinase, putative 0.0152 0.0395 0.2095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0105 0.0519
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0034 0.0034
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0096 0.0096
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0254 0.0687 0.0883
Onchocerca volvulus 0.0027 0.0038 0.0048
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0014 0.0001 0.0001
Schistosoma mansoni lamin 0.011 0.0276 0.0276
Schistosoma mansoni tyrosine kinase 0.0146 0.0379 0.0379
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Echinococcus granulosus neurogenic locus notch protein 0.0485 0.1351 0.1351
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0059 0.0129 0.0166
Schistosoma mansoni tyrosine kinase 0.0079 0.0185 0.0185
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0065 0.0147 0.0147
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0008 0.0045
Trichomonas vaginalis histone deacetylase, putative 0.0398 0.1101 0.5472
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0672 0.1888 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Echinococcus granulosus fatty acid binding protein FABP2 0.0034 0.0056 0.0056
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0361 1
Echinococcus granulosus hypothetical protein 0.0065 0.0147 0.0147
Plasmodium falciparum thioredoxin reductase 0.005 0.0101 0.0915
Schistosoma mansoni pyruvate kinase 0.0035 0.0059 0.0059
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0629 0.1762 0.2265
Loa Loa (eye worm) neuropeptide F receptor 0.0065 0.0147 0.0189
Echinococcus granulosus dnaJ subfamily B 0.0427 0.1183 0.1183
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0008 0.0071
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0065 0.0147 0.0147
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0014 0.0001 0.0003
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Echinococcus granulosus lamin 0.011 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.01 0.0245 0.0315
Onchocerca volvulus 0.0019 0.0013 0.0016
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0002 0.0002
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0105 0.0134
Brugia malayi nuclear receptor RXR 0.0051 0.0106 0.0136
Leishmania major cathepsin L-like protease 0.0051 0.0105 0.0556
Echinococcus multilocularis L aminoadipate semialdehyde 0.0173 0.0456 0.0456
Onchocerca volvulus 0.011 0.0276 0.0354
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0086 0.0455
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0075 0.0397
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0049 0.0099 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.006 0.0295
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0105 0.0953
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0003 0.0003
Echinococcus granulosus single minded 2 0.0035 0.0061 0.0061
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0065 0.0147 0.0147
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0045
Schistosoma mansoni tyrosine kinase 0.0079 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0108 0.027 0.0347
Trypanosoma cruzi histone deacetylase, putative 0.0143 0.0368 0.1952
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0085 0.0418
Brugia malayi Animal haem peroxidase family protein 0.2727 0.7781 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0045
Brugia malayi orphan nuclear receptor NR2E1 0.0051 0.0106 0.0136
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0001 0.0003
Schistosoma mansoni glucose transport protein 0.0014 0.0001 0.0001
Echinococcus granulosus alpha 1A adrenergic receptor 0.0065 0.0147 0.0147
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0045
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0108 0.027 0.027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0687 0.3414
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0108 0.027 0.0347
Trypanosoma brucei glucose transporter, putative 0.0014 0.0001 0.0003
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0037 0.0064 0.0335
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0113 0.0283 0.1501
Leishmania major cathepsin L-like protease 0.0051 0.0105 0.0556
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0094
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0002 0.0002
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0038 0.0048
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0279 0.1384
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0065 0.0147 0.0189
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0672 0.1888 1
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0514 0.2724
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Echinococcus multilocularis neural cadherin 0.0485 0.1351 0.1351
Loa Loa (eye worm) hypothetical protein 0.0057 0.0124 0.0159
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0013 0.0017
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0108 0.027 0.027
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.0375 0.0483
Echinococcus granulosus solute carrier family 22 0.0014 0.0001 0.0001
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0279 0.1384
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Plasmodium vivax flavodoxin domain containing protein 0.0023 0.0026 0.023
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0012 0.0058
Toxoplasma gondii glyoxalase family protein 0.0044 0.0085 0.0622
Echinococcus multilocularis neurogenic locus protein delta 0.0485 0.1351 0.1351
Brugia malayi Nuclear hormone receptor E75 0.0051 0.0106 0.0136
Loa Loa (eye worm) cytochrome P450 family protein 0.0075 0.0175 0.0225
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0125 0.0125
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.007 0.007
Schistosoma mansoni cytochrome P450 0.0037 0.0064 0.0064
Onchocerca volvulus 0.006 0.0131 0.0167
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0059 0.0075
Echinococcus multilocularis histone deacetylase 0.0143 0.0368 0.0368
Brugia malayi EGF-like domain containing protein 0.0485 0.1351 0.1736
Schistosoma mansoni pyruvate kinase 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Onchocerca volvulus 0.0485 0.1351 0.1735
Loa Loa (eye worm) hypothetical protein 0.011 0.0276 0.0355
Echinococcus granulosus rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0194 0.0515 0.0515
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0105 0.0519
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0021 0.0027
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0121 0.0891
Schistosoma mansoni biogenic amine receptor 0.0065 0.0147 0.0147
Schistosoma mansoni cytochrome P450 reductase 0.0026 0.0035 0.0035
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0279 0.1384
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0053 0.0391
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0005
Onchocerca volvulus 0.0108 0.027 0.0346
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0034 0.0311
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Echinococcus multilocularis protein jagged 2 0.0485 0.1351 0.1351
Echinococcus multilocularis cpg binding protein 0.0063 0.0141 0.0141
Brugia malayi cathepsin L-like precursor 0.0034 0.0057 0.0073
Trichomonas vaginalis aldo/keto reductase, putative 0.0111 0.0279 0.1384
Brugia malayi Calcium binding EGF domain containing protein 0.0485 0.1351 0.1736
Echinococcus granulosus g protein coupled receptor 0.0065 0.0147 0.0147
Loa Loa (eye worm) animal heme peroxidase 0.2727 0.7781 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0194 0.0515 0.0515
Echinococcus multilocularis serotonin receptor 0.0065 0.0147 0.0147
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0065 0.0147 0.0147
Onchocerca volvulus 0.0044 0.0084 0.0108
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0101 0.0915
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0002 0.0009
Echinococcus multilocularis neurogenic locus protein delta 0.0485 0.1351 0.1351
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0065 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0111 0.0279 0.0358
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0108 0.027 0.0347
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0102 0.0253 0.0253
Brugia malayi conserved hypotetical protein 0.0051 0.0106 0.0136
Schistosoma mansoni gynecophoral canal protein 0.0044 0.0085 0.0085
Brugia malayi G protein-coupled receptor 0.0065 0.0147 0.0189
Mycobacterium leprae putative cytochrome p450 0.0037 0.0064 0.0176
Mycobacterium tuberculosis Conserved protein 0.0044 0.0085 0.0448
Brugia malayi hypothetical protein 0.0044 0.0084 0.0108
Trypanosoma cruzi cruzipain precursor, putative 0.0017 0.0007 0.0039
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0037 0.0064 0.0335
Echinococcus granulosus histone deacetylase 6 0.0143 0.0368 0.0368
Giardia lamblia DINP protein human, muc B family 0.0021 0.0019 0.0133
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0044 0.0084 0.0443
Plasmodium vivax vivapain-1 0.0026 0.0034 0.0306
Echinococcus multilocularis lipoxygenase domain containing protein 0.014 0.0362 0.0362
Brugia malayi G-protein coupled receptor 0.0065 0.0147 0.0189
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0038 0.0038
Trypanosoma cruzi cysteine peptidase, putative 0.0026 0.0034 0.0181
Onchocerca volvulus Slit protein homolog 0.0485 0.1351 0.1735
Echinococcus granulosus tachykinin peptides receptor 99D 0.0065 0.0147 0.0147
Echinococcus granulosus histone deacetylase 1 0.0398 0.1101 0.1101
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.007 0.0372
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0049
Echinococcus granulosus pyruvate kinase 0.0035 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0274 0.0746 0.0959
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0045
Loa Loa (eye worm) histone deacetylase 11 0.0143 0.0368 0.0473
Echinococcus granulosus Polycystic kidney disease protein 0.014 0.0362 0.0362
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0121 0.1099
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0082 0.06
Loa Loa (eye worm) hypothetical protein 0.0099 0.0245 0.0314
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0221 0.1633
Brugia malayi Animal haem peroxidase family protein 0.2727 0.7781 1
Plasmodium falciparum histone deacetylase, putative 0.0143 0.0368 0.3344
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0053 0.0263
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0037 0.0064 0.0335
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0059 0.0075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0065 0.0147 0.0147
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0108 0.027 0.027
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.007 0.5783
Brugia malayi G-protein coupled receptor 0.0065 0.0147 0.0189
Onchocerca volvulus 0.0485 0.1351 0.1735
Entamoeba histolytica cysteine protease, putative 0.0026 0.0034 0.0311
Onchocerca volvulus 0.0051 0.0105 0.0134
Schistosoma mansoni fatty acid binding protein 0.0034 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0003
Trypanosoma brucei aldo/keto reductase, putative 0.0045 0.0089 0.0469
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0033 0.029
Leishmania major glucose transporter, lmgt2 0.0014 0.0001 0.0003
Schistosoma mansoni ap endonuclease 0.0056 0.0121 0.0121
Leishmania major hypothetical protein, conserved 0.0015 0.0003 0.0018
Plasmodium falciparum cysteine proteinase falcipain 3 0.0051 0.0105 0.0948
Trypanosoma brucei cytochrome P450, putative 0.0046 0.009 0.0477
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0108 0.027 0.027
Giardia lamblia Nitric oxide synthase, inducible 0.0023 0.0026 0.0188
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0013 0.0017
Onchocerca volvulus Cathepsin F homolog 0.0051 0.0105 0.0134
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0279 0.0279
Entamoeba histolytica hypothetical protein 0.0077 0.0181 0.1642
Onchocerca volvulus 0.0065 0.0147 0.0188
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.0085 0.0448
Loa Loa (eye worm) FAD binding domain-containing protein 0.0026 0.0035 0.0044
Brugia malayi Melatonin receptor type 1A 0.0065 0.0147 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0053 0.0263
Brugia malayi hypothetical protein 0.0065 0.0147 0.0189
Echinococcus granulosus g protein coupled receptor 0.0065 0.0147 0.0147
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.0375 0.0375
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0049 0.0099 0.8161
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Loa Loa (eye worm) hypothetical protein 0.2727 0.7781 1
Echinococcus granulosus voltage gated potassium channel subunit 0.0045 0.0089 0.0089
Plasmodium falciparum aldehyde reductase, putative 0.0045 0.0089 0.0799
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Loa Loa (eye worm) hypothetical protein 0.0173 0.0456 0.0586
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0108 0.027 0.0347
Trypanosoma brucei histone deacetylase 1 0.0398 0.1101 0.5831
Echinococcus multilocularis GPCR, family 2 0.0098 0.024 0.024
Echinococcus granulosus thyroid hormone receptor alpha 0.0051 0.0106 0.0106
Onchocerca volvulus 0.0044 0.0084 0.0108
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0279 0.0279
Brugia malayi larval opioid receptor 0.0065 0.0147 0.0189
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Schistosoma mansoni amine GPCR 0.0065 0.0147 0.0147
Plasmodium vivax vivapain-2 0.0051 0.0105 0.0948
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0279 0.0358
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0037 0.0064 0.0339
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0034 0.0056 0.0073
Echinococcus multilocularis histone deacetylase 1 0.0398 0.1101 0.1101
Schistosoma mansoni hypothetical protein 0.0485 0.1351 0.1351
Leishmania major cathepsin L-like protease 0.0193 0.0514 0.2724
Plasmodium vivax histone deacetylase 1, putative 0.0398 0.1101 1
Schistosoma mansoni histone deacetylase 4 5 0.0143 0.0368 0.0368
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0108 0.027 0.027
Echinococcus multilocularis agrin 0.0019 0.0013 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0105 0.0519
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0053 0.0263
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0037 0.0064 0.0339
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0065 0.0147 0.0147
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0279 0.0279
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0038 0.0038
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0045
Leishmania major trypanothione reductase 0.005 0.0101 0.0537
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0065 0.0147 0.0189
Echinococcus multilocularis fatty acid binding protein FABP2 0.0034 0.0056 0.0056
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.007 0.0346
Schistosoma mansoni hypothetical protein 0.0098 0.024 0.024
Brugia malayi hypoxia-induced factor 1 0.0148 0.0383 0.0493
Schistosoma mansoni hypothetical protein 0.0015 0.0002 0.0002
Plasmodium falciparum pyruvate kinase 2 0.0018 0.001 0.0089
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0001 0.0001
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0279 0.0279
Trypanosoma brucei histone deacetylase 3 0.0143 0.0368 0.1952
Brugia malayi CHD4 protein 0.0015 0.0001 0.0001
Echinococcus multilocularis neuropeptide Y receptor 0.0065 0.0147 0.0147
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0065 0.0147 0.0147
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0121 0.0121
Brugia malayi hypothetical protein 0.014 0.0362 0.0465
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0008 0.0045
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0121 0.0641
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0121 0.0641
Echinococcus multilocularis g protein coupled receptor 0.0065 0.0147 0.0147
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0065 0.0147 0.0189
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0071 0.0644
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0037 0.0064 0.0064
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0279 0.0279
Brugia malayi Death domain containing protein 0.0015 0.0002 0.0003
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0008 0.0295
Echinococcus granulosus cathepsin L cysteine protease 0.0026 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0098 0.024 0.0308
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0279 0.0279
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0037 0.0064 0.0335
Schistosoma mansoni thyroid hormone receptor 0.0357 0.0984 0.0984
Trypanosoma cruzi histone deacetylase, putative 0.0143 0.0368 0.1952
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0205 0.0548 0.0548
Echinococcus granulosus somatostatin receptor 0.0065 0.0147 0.0147
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0279 0.0279
Loa Loa (eye worm) oxidoreductase 0.0044 0.0084 0.0108
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0003 0.0003
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.009 0.0477
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0514 0.2724
Mycobacterium ulcerans hypothetical protein 0.0044 0.0085 0.0445
Toxoplasma gondii cathepsin CPL 0.0051 0.0105 0.0772
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Onchocerca volvulus Phospholipase A2 homolog 0.0274 0.0746 0.0958
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0059 0.031
Brugia malayi hypothetical protein 0.01 0.0245 0.0315
Echinococcus granulosus protein jagged 1 0.0485 0.1351 0.1351
Loa Loa (eye worm) hypothetical protein 0.0065 0.0147 0.0189
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0099 0.0524
Onchocerca volvulus Dual oxidase homolog 0.2727 0.7781 1
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0485 0.1351 0.1736
Brugia malayi cathepsin F-like cysteine proteinase 0.0017 0.0007 0.0009
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0065 0.0147 0.0147
Brugia malayi hypothetical protein 0.0051 0.0106 0.0136
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0279 0.0279
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0086 0.078
Brugia malayi EGF-like domain containing protein 0.0485 0.1351 0.1736
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0059 0.0075
Loa Loa (eye worm) oxidoreductase 0.0111 0.0279 0.0358
Leishmania major histone deacetylase, putative 0.0143 0.0368 0.1952
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0002 0.0009
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0084 0.0108
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0194 0.0515 0.0515
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0013 0.0091
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0437 0.2169
Schistosoma mansoni septate junction protein 0.0485 0.1351 0.1351
Leishmania major cathepsin L-like protease 0.0051 0.0105 0.0556
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.0333 0.0333

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 0.00000000015 M Differentiation inducing activity towards human promyelocytic leukemia cell line HL-60 assayed by nitroblue tetrazolium reduction ChEMBL. 2704028
ED50 (functional) = 0.00000000015 M Differentiation inducing activity towards human promyelocytic leukemia cell line HL-60 assayed by nitroblue tetrazolium reduction ChEMBL. 2704028
Relative activity (functional) = 1.4 Activity of the compound relative to retinoic acid in differentiating promyelocytic leukemic HL-60 cells ChEMBL. 2704028

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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