Detailed information for compound 316351

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 566.456 | Formula: C26H31BrF3N5O
  • H donors: 2 H acceptors: 2 LogP: 6.97 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: Brc1ccc(c(c1)OC(F)(F)F)CNCC1CCC(CC1)CNc1nc2ccccc2c(n1)N(C)C
  • InChi: 1S/C26H31BrF3N5O/c1-35(2)24-21-5-3-4-6-22(21)33-25(34-24)32-15-18-9-7-17(8-10-18)14-31-16-19-11-12-20(27)13-23(19)36-26(28,29)30/h3-6,11-13,17-18,31H,7-10,14-16H2,1-2H3,(H,32,33,34)
  • InChiKey: UGTJLUOFSLGNDT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens melanin-concentrating hormone receptor 1 Starlite/ChEMBL References
Homo sapiens neuropeptide Y receptor Y5 Starlite/ChEMBL References
Homo sapiens adrenoceptor alpha 2A Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0014 0.0037 0.0052
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0139 0.0141
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0185 0.0203
Onchocerca volvulus 0.0031 0.022 0.04
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Onchocerca volvulus 0.0014 0.0037 0.0052
Onchocerca volvulus 0.022 0.2192 0.4137
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0102 0.0106
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0059 0.0511 0.0511
Plasmodium falciparum heat shock protein 90, putative 0.0931 0.9638 1
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0041 0.0323 0.0323
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0059 0.0511 0.055
Schistosoma mansoni cpg binding protein 0.003 0.0207 0.0222
Echinococcus multilocularis neuropeptides capa receptor 0.0059 0.0511 0.0511
Brugia malayi hypothetical protein 0.0018 0.008 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0286 0.0575
Mycobacterium tuberculosis Probable sulfatase 0.0028 0.0182 0.0314
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0452 0.0452
Schistosoma mansoni tyrosine kinase 0.0185 0.1823 0.1964
Echinococcus granulosus cpg binding protein 0.0032 0.0224 0.0224
Echinococcus granulosus tubulin epsilon chain 0.0255 0.2562 0.2562
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0069 0.061 0.0767
Brugia malayi Cell death specification protein 2 0.0018 0.008 0.0083
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0046 0.0075
Brugia malayi hypothetical protein 0.0028 0.0185 0.0192
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0019 0.0091 0.0094
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0102 0.0093
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0102 0.0193
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0185 0.0192
Echinococcus multilocularis MORC family CW type zinc finger protein 2B 0.002 0.0103 0.0103
Loa Loa (eye worm) carboxylesterase 0.0013 0.0032 0.0057
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0139 0.0143
Schistosoma mansoni gliotactin 0.0013 0.0032 0.0033
Brugia malayi hypothetical protein 0.0048 0.0392 0.0407
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0041 0.0323 0.1168
Leishmania major importin beta-1 subunit, putative 0.0026 0.0164 0.018
Echinococcus multilocularis raf serine:threonine protein kinase 0.005 0.0411 0.0411
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0059 0.0511 0.055
Trypanosoma brucei epsilon tubulin 0.0255 0.2562 0.3358
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.0452 0.0486
Brugia malayi ORL1-like opioid receptor 0.0059 0.0511 0.0531
Echinococcus granulosus protein farnesyltransferase subunit beta 0.002 0.0102 0.0102
Schistosoma mansoni sugar transporter 0.0015 0.0046 0.0049
Echinococcus multilocularis heat shock protein 90 0.0273 0.2744 0.2744
Echinococcus granulosus protocadherin 11 0.0018 0.008 0.008
Onchocerca volvulus Phospholipase A2 homolog 0.0107 0.1012 0.1901
Trypanosoma brucei epsilon tubulin 0.0255 0.2562 0.3358
Loa Loa (eye worm) TOPoisomerase family member 0.0041 0.0323 0.0581
Brugia malayi SRC-1 0.0056 0.0474 0.0494
Echinococcus granulosus neuropeptide Y receptor 0.0059 0.0511 0.0511
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0059 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0012 0.0022 0.004
Brugia malayi Pre-SET motif family protein 0.0028 0.0188 0.0195
Loa Loa (eye worm) hypothetical protein 0.0245 0.246 0.4432
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Loa Loa (eye worm) hypothetical protein 0.0013 0.0032 0.0057
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0048 0.0392 0.0392
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0041 0.0323 0.0608
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0231 0.0459
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0452 0.047
Echinococcus multilocularis G protein coupled receptor 139 0.0059 0.0511 0.0511
Onchocerca volvulus Huntingtin homolog 0.0384 0.3911 0.7396
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0076 0.0076
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Echinococcus multilocularis solute carrier family 22 0.0015 0.0046 0.0046
Brugia malayi putative neuropeptide receptor 0.0059 0.0511 0.0531
Schistosoma mansoni tyrosine kinase 0.0113 0.1078 0.1162
Plasmodium falciparum tubulin delta chain, putative 0.0111 0.1051 0.109
Loa Loa (eye worm) tubulin alpha 2 0.0101 0.0949 0.171
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.002 0.0102 0.0106
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0059 0.0511 0.0511
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0059 0.0511 0.0511
Echinococcus granulosus serotonin receptor 0.0059 0.0511 0.0511
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.0984 0.0984
Echinococcus multilocularis tubulin subunit TubB 0.0356 0.3619 0.3619
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.01 0.0107
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0227 0.0259
Brugia malayi RNA binding protein 0.0262 0.2629 0.2738
Brugia malayi Probable DNA topoisomerase II 0.0041 0.0323 0.0336
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0019 0.0091 0.0163
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0231 0.0459
Brugia malayi SEA domain containing protein 0.0014 0.0037 0.0038
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0036 0.027 0.0315
Schistosoma mansoni nAChR subunit 0.0019 0.0091 0.0097
Mycobacterium ulcerans DNA gyrase subunit B 0.0041 0.0323 0.1168
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0017 0.0073 0.0078
Schistosoma mansoni alpha tubulin 0.0356 0.3619 0.3902
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0048 0.0392 0.0392
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0046 0.0082
Loa Loa (eye worm) hypothetical protein 0.0212 0.2109 0.3799
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Loa Loa (eye worm) hypothetical protein 0.0013 0.0032 0.0057
Trypanosoma cruzi tubulin delta chain 0.0111 0.1051 0.1353
Echinococcus granulosus tubulin subunit TubB 0.0356 0.3619 0.3619
Trypanosoma brucei heat shock protein, putative 0.0273 0.2744 0.36
Trichomonas vaginalis heat shock protein, putative 0.0231 0.2313 0.4789
Loa Loa (eye worm) hypothetical protein 0.0541 0.5551 1
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0231 0.0459
Onchocerca volvulus 0.0015 0.0046 0.0068
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0036 0.0268 0.0268
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0091 0.0094
Brugia malayi nuclear receptor RXR 0.0025 0.0156 0.0162
Plasmodium vivax DNA gyrase subunit B, putative 0.0041 0.0323 0.0289
Leishmania major beta tubulin 0.0471 0.482 0.6538
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0041 0.0323 0.0581
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0323 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0001 0.0001
Schistosoma mansoni amine GPCR 0.0059 0.0511 0.055
Schistosoma mansoni nAChR subunit 0.0019 0.0091 0.0097
Loa Loa (eye worm) hypothetical protein 0.0356 0.3619 0.652
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.003 0.0054
Plasmodium falciparum alpha tubulin 2 0.0356 0.3619 0.3755
Echinococcus granulosus dro:myosuppressin receptor 0.0059 0.0511 0.0511
Leishmania major beta tubulin 0.0471 0.482 0.6538
Trichomonas vaginalis mismatch repair protein Mlh3 (mutL homolog) 0.002 0.0103 0.0194
Giardia lamblia Heat shock protein HSP 90-alpha 0.0273 0.2744 0.336
Schistosoma mansoni tubulin subunit alpha 0.0111 0.1051 0.1133
Brugia malayi Serotonin receptor 0.0594 0.6111 0.6365
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0091 0.0091
Trypanosoma brucei alpha tubulin, putative 0.0144 0.1403 0.1819
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0017 0.0073 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Brugia malayi conserved hypotetical protein 0.0025 0.0156 0.0162
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0036 0.027 0.0541
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Brugia malayi hypothetical protein 0.0059 0.0511 0.0531
Schistosoma mansoni lozenge 0.0065 0.0568 0.0612
Toxoplasma gondii Hsp90 domain-containing protein 0.0931 0.9638 1
Schistosoma mansoni intermediate filament proteins 0.0031 0.022 0.0237
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0053 0.0452 0.0486
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0185 0.0203
Echinococcus granulosus snurportin 1 0.0342 0.3472 0.3472
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus multilocularis para nitrobenzyl esterase 0.0013 0.0032 0.0032
Brugia malayi MH1 domain containing protein 0.0018 0.0076 0.0078
Loa Loa (eye worm) hypothetical protein 0.0053 0.0452 0.0814
Loa Loa (eye worm) isocitrate dehydrogenase 0.0036 0.0268 0.0483
Echinococcus granulosus c src tyrosine kinase 0.0022 0.0119 0.0119
Schistosoma mansoni lamin 0.0031 0.022 0.0237
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0231 0.0263
Onchocerca volvulus 0.0019 0.0091 0.0154
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Entamoeba histolytica tubulin alpha chain, putative 0.0356 0.3619 0.4425
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Mycobacterium tuberculosis Cell division protein FtsZ 0.0111 0.1051 0.2129
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.0032 0.0228 0.0245
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0286 0.0286
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0255 0.2562 0.2658
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0019 0.0091 0.0094
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0048 0.0392 0.0422
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Onchocerca volvulus 0.0013 0.0032 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0511 0.055
Trichomonas vaginalis tubulin, putative 0.0471 0.482 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0392 0.0407
Onchocerca volvulus 0.0059 0.0511 0.095
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0102 0.0093
Echinococcus granulosus alpha 1A adrenergic receptor 0.0059 0.0511 0.0511
Trichomonas vaginalis tubulin epsilon chain, putative 0.0471 0.482 1
Schistosoma mansoni tubulin subunit epsilon 0.0255 0.2562 0.2762
Schistosoma mansoni growth factor receptor-bound protein 0.0017 0.0073 0.0078
Echinococcus granulosus g protein coupled receptor 0.0059 0.0511 0.0511
Echinococcus granulosus tubulin gamma 1 chain 0.0255 0.2562 0.2562
Schistosoma mansoni thyroid hormone receptor 0.0053 0.0452 0.0486
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0156 0.0156
Loa Loa (eye worm) tubulin alpha chain 0.0356 0.3619 0.652
Toxoplasma gondii beta-tubulin, putative 0.0471 0.482 0.5001
Loa Loa (eye worm) hypothetical protein 0.0018 0.008 0.0145
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0059 0.0511 0.092
Onchocerca volvulus Bile acid receptor homolog 0.0053 0.0452 0.0838
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0173 0.1707 0.1707
Leishmania major alpha tubulin 0.0356 0.3619 0.4898
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0028 0.0182 0.0314
Echinococcus granulosus epidermal growth factor receptor 0.035 0.3549 0.3549
Loa Loa (eye worm) hypothetical protein 0.0053 0.0452 0.0814
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0036 0.0268 0.0288
Loa Loa (eye worm) hypothetical protein 0.0018 0.008 0.0145
Toxoplasma gondii sugar transporter ST1 0.0015 0.0046 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0452 0.047
Leishmania major mitochondrial DNA topoisomerase II 0.0041 0.0323 0.0396
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0076 0.0076
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0041 0.0323 0.1168
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.003 0.0054
Leishmania major heat shock protein, putative 0.0173 0.1707 0.2286
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0001 0.0001
Plasmodium falciparum tubulin beta chain 0.0471 0.482 0.5001
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0001 0.0001
Echinococcus multilocularis FTZ F1 alpha 0.0053 0.0452 0.0452
Brugia malayi Carboxylesterase family protein 0.0013 0.0032 0.0032
Schistosoma mansoni tyrosine kinase 0.0013 0.003 0.0032
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0392 0.0407
Echinococcus granulosus tm gpcr rhodopsin 0.0059 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0048 0.0392 0.0706
Echinococcus granulosus G protein signaling modulator 2 0.0013 0.0024 0.0024
Brugia malayi Variant SH3 domain containing protein 0.0017 0.0073 0.0076
Loa Loa (eye worm) TK/EGFR protein kinase 0.035 0.3549 0.6393
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0046 0.0049
Onchocerca volvulus 0.0019 0.0091 0.0154
Leishmania major alpha tubulin 0.0356 0.3619 0.4898
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0392 0.0406
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0053 0.0452 0.0814
Brugia malayi Tubulin beta-1 chain 0.0471 0.482 0.502
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0015 0.0046 0.0029
Brugia malayi MH2 domain containing protein 0.0258 0.2588 0.2694
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0392 0.0422
Entamoeba histolytica DNA mismatch repair protein MLH1, putative 0.002 0.0103 0.0114
Echinococcus multilocularis insulin receptor 0.0113 0.1078 0.1078
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0188 0.0188
Echinococcus granulosus importin subunit beta 1 0.0032 0.0227 0.0227
Leishmania major DNA topoisomerase ii 0.0041 0.0323 0.0396
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0028 0.0188 0.0188
Schistosoma mansoni Microrchidia 2a 0.002 0.0103 0.011
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0036 0.0268 0.0268
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0083 0.0766 0.0766
Trichomonas vaginalis DNA topoisomerase II, putative 0.0041 0.0323 0.0651
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0091 0.0094
Loa Loa (eye worm) tubulin alpha 2 0.0245 0.246 0.4432
Schistosoma mansoni tyrosine kinase 0.0189 0.1869 0.2014
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0041 0.0323 0.0651
Loa Loa (eye worm) hypothetical protein 0.0201 0.1993 0.359
Leishmania major hypothetical protein, conserved 0.0028 0.0185 0.0209
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0041 0.0323 0.1118
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0156 0.0162
Echinococcus multilocularis tubulin alpha chain 0.0356 0.3619 0.3619
Loa Loa (eye worm) hypothetical protein 0.0281 0.2836 0.5108
Toxoplasma gondii isocitrate dehydrogenase 0.0036 0.0268 0.0278
Trypanosoma brucei alpha tubulin 0.0356 0.3619 0.4761
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0053 0.0452 0.0452
Brugia malayi hypothetical protein 0.0015 0.0048 0.0049
Echinococcus granulosus ecdysone induced protein 78C 0.0053 0.0452 0.0452
Trichomonas vaginalis endoplasmin, putative 0.0194 0.1927 0.3985
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0069 0.061 0.1248
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Echinococcus granulosus geminin 0.0897 0.9276 0.9276
Schistosoma mansoni hypothetical protein 0.0083 0.0766 0.0825
Echinococcus multilocularis Tubulin beta 2C chain 0.0471 0.482 0.482
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0036 0.0268 0.0232
Entamoeba histolytica peptidase, C54 family 0.0027 0.0172 0.0199
Loa Loa (eye worm) hypothetical protein 0.0025 0.0156 0.0281
Trypanosoma cruzi tubulin gamma chain 0.0255 0.2562 0.3358
Onchocerca volvulus 0.0014 0.0037 0.0052
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0053 0.0452 0.0814
Loa Loa (eye worm) DOMON domain-containing protein 0.0014 0.0037 0.0067
Schistosoma mansoni tubulin subunit alpha 0.0356 0.3619 0.3902
Brugia malayi major facilitator superfamily protein 0.0015 0.0046 0.0047
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0091 0.0091
Trypanosoma brucei mismatch repair protein MLH1 0.002 0.0103 0.0093
Toxoplasma gondii beta-1 tubulin, putative 0.0471 0.482 0.5001
Schistosoma mansoni zinc finger protein 0.0025 0.0156 0.0168
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0059 0.0511 0.0511
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0069 0.061 0.0657
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.1292
Echinococcus multilocularis somatostatin receptor 0.0059 0.0511 0.0511
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.003 0.0054
Schistosoma mansoni biogenic amine receptor 0.0059 0.0511 0.055
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0036 0.0268 0.0278
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0231 0.0271
Trypanosoma brucei beta tubulin 0.0255 0.2562 0.3358
Brugia malayi AKH receptor 0.0059 0.0511 0.0531
Leishmania major beta tubulin 0.0471 0.482 0.6538
Loa Loa (eye worm) SMO-1 protein 0.0032 0.0228 0.0411
Brugia malayi Variant SH3 domain containing protein 0.0017 0.0073 0.0076
Plasmodium vivax amine transporter, putative 0.0048 0.0392 0.0361
Loa Loa (eye worm) tubulin beta chain 0.0111 0.1051 0.1894
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0046 0.0082
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0012 0.0022 0.0022
Echinococcus granulosus orexin receptor type 2 0.0059 0.0511 0.0511
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Schistosoma mansoni hypothetical protein 0.002 0.0103 0.011
Loa Loa (eye worm) BEN-1 protein 0.0471 0.482 0.8684
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0047 0.0385 0.0385
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0281 0.2836 0.3057
Echinococcus granulosus Tubulin beta 2C chain 0.0471 0.482 0.482
Loa Loa (eye worm) runx1 0.0065 0.0568 0.1024
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0059 0.0511 0.092
Entamoeba histolytica hypothetical protein 0.0018 0.008 0.0087
Toxoplasma gondii DNA mismatch repair protein, C-terminal domain-containing protein 0.002 0.0103 0.0106
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0156 0.0281
Toxoplasma gondii alpha-tubulin I, putative 0.0356 0.3619 0.3755
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0059 0.0511 0.0511
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0019 0.0091 0.0094
Echinococcus multilocularis neuropeptide receptor 0.0059 0.0511 0.0511
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0048 0.0392 0.0706
Trypanosoma cruzi lanosterol synthase, putative 0.0733 0.7566 1
Schistosoma mansoni hypothetical protein 0.0014 0.0037 0.0039
Onchocerca volvulus 0.0015 0.0046 0.0068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0053 0.0452 0.0814
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus granulosus tubulin delta chain 0.0111 0.1051 0.1051
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Plasmodium vivax heat shock protein 90, putative 0.0173 0.1707 0.1732
Echinococcus granulosus Tubulin beta 2C chain 0.0471 0.482 0.482
Schistosoma mansoni nuclear hormone receptor 0.0053 0.0452 0.0486
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0185 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0046 0.0075
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0231 0.0263
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0041 0.0323 0.7611
Plasmodium falciparum heat shock protein 90 0.0273 0.2744 0.2847
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0091 0.0094
Echinococcus multilocularis orexin receptor type 2 0.0059 0.0511 0.0511
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0102 0.0193
Loa Loa (eye worm) tubulin beta-2A chain 0.0471 0.482 0.8684
Echinococcus granulosus hypothetical protein 0.0862 0.8912 0.8912
Loa Loa (eye worm) hypothetical protein 0.0025 0.0156 0.0281
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0013 0.003 0.003
Schistosoma mansoni sodium/chloride dependent transporter 0.0281 0.2836 0.3057
Leishmania major beta tubulin 0.0471 0.482 0.6538
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Brugia malayi Cell death specification protein 2 0.0018 0.008 0.0083
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0036 0.0268 0.0313
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0056 0.0474 0.0474
Entamoeba histolytica peptidase, C54 family 0.0027 0.0172 0.0199
Trypanosoma brucei heat shock protein, putative 0.0273 0.2744 0.36
Schistosoma mansoni hypothetical protein 0.0015 0.0048 0.0051
Trypanosoma brucei zeta tubulin 0.0111 0.1051 0.1353
Brugia malayi hypothetical protein 0.0013 0.003 0.0031
Echinococcus multilocularis Tubulin beta 2C chain 0.0471 0.482 0.482
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Brugia malayi Hepatic leukemia factor 0.0018 0.008 0.0083
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0036 0.027 0.027
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0083 0.0766 0.0797
Schistosoma mansoni protein farnesyltransferase subunit beta 0.002 0.0102 0.011
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0017 0.0073 0.0132
Echinococcus granulosus epidermal growth factor receptor 0.0189 0.1869 0.1869
Leishmania major alpha tubulin 0.0356 0.3619 0.4898
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0156 0.0162
Trypanosoma brucei lanosterol synthase 0.0733 0.7566 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0018 0.008 0.008
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0041 0.0323 0.0608
Schistosoma mansoni coup transcription factor 0.0053 0.0452 0.0486
Onchocerca volvulus 0.0059 0.0511 0.095
Loa Loa (eye worm) hypothetical protein 0.0079 0.0717 0.1292
Loa Loa (eye worm) hypothetical protein 0.0264 0.2653 0.4779
Trichomonas vaginalis receptor histidine kinase, putative 0.0041 0.0323 0.0651
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Brugia malayi Dopamine receptor 0.0059 0.0511 0.0531
Leishmania major alpha tubulin 0.0356 0.3619 0.4898
Trypanosoma cruzi small ubiquitin protein, putative 0.0032 0.0228 0.0259
Echinococcus multilocularis neuropeptides capa receptor 0.0059 0.0511 0.0511
Onchocerca volvulus 0.0059 0.0511 0.095
Echinococcus granulosus peroxisome assembly protein 26 0.0356 0.3619 0.3619
Echinococcus multilocularis heat shock protein 0.0273 0.2744 0.2744
Mycobacterium ulcerans arylsulfatase, AslA 0.0028 0.0182 0.0603
Trypanosoma brucei glucose transporter 1E 0.0032 0.0231 0.0263
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0091 0.0091
Echinococcus granulosus tyrosine protein kinase Fyn 0.0056 0.0474 0.0474
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0155 0.0155
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0392 0.0406
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0452 0.047
Plasmodium falciparum small ubiquitin-related modifier 0.0032 0.0228 0.0236
Schistosoma mansoni tubulin subunit delta 0.0111 0.1051 0.1133
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0059 0.0511 0.055
Loa Loa (eye worm) hypothetical protein 0.002 0.0103 0.0185
Trypanosoma brucei glucose transporter, putative 0.0032 0.0231 0.0263
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0231 0.0459
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0511 0.055
Echinococcus multilocularis Small ubiquitin modifier 2 0.0032 0.0228 0.0228
Schistosoma mansoni opsin-like receptor 0.0059 0.0511 0.055
Onchocerca volvulus 0.0013 0.0032 0.0042
Trichomonas vaginalis mismatch repair protein Mlh1B (mutL homolog) 0.002 0.0103 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0102 0.0106
Echinococcus multilocularis 0.0107 0.1016 0.1016
Loa Loa (eye worm) hypothetical protein 0.0038 0.0286 0.0516
Onchocerca volvulus 0.0015 0.0046 0.0068
Schistosoma mansoni DNA mismatch repair protein PMS2 0.002 0.0103 0.011
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0392 0.0422
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0156 0.0162
Plasmodium vivax DNA mismatch repair protein PMS1, putative 0.002 0.0103 0.006
Loa Loa (eye worm) TK/INSR protein kinase 0.0113 0.1078 0.1942
Echinococcus granulosus Peptidase C54 0.0069 0.061 0.061
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.057 0.0614
Toxoplasma gondii isocitrate dehydrogenase 0.0036 0.0268 0.0278
Toxoplasma gondii transporter, major facilitator family protein 0.0015 0.0046 0.0047
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0048 0.0392 0.0407
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0019 0.0091 0.0097
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0019 0.0091 0.0091
Trypanosoma brucei heat shock protein 84, putative 0.0173 0.1707 0.2222
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.002 0.0102 0.0193
Echinococcus multilocularis peroxisome assembly protein 26 0.0356 0.3619 0.3619
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0036 0.027 0.0541
Schistosoma mansoni alpha tubulin 0.0356 0.3619 0.3902
Loa Loa (eye worm) GoLoco domain-containing protein family protein 0.0013 0.0024 0.0043
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0036 0.027 0.0319
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Onchocerca volvulus 0.0025 0.0156 0.0278
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0188 0.0338
Loa Loa (eye worm) hypothetical protein 0.0107 0.1012 0.1823
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0041 0.0323 0.0385
Leishmania major beta tubulin 0.0471 0.482 0.6538
Echinococcus multilocularis Protein lozenge 0.0065 0.0568 0.0568
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Onchocerca volvulus Putative transporter 0.0015 0.0046 0.0068
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.002 0.0102 0.0102
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0013 0.003 0.003
Echinococcus multilocularis musashi 0.0031 0.022 0.022
Echinococcus multilocularis g protein coupled receptor 0.0059 0.0511 0.0511
Brugia malayi tailless protein 0.0025 0.0156 0.0162
Echinococcus granulosus tubulin beta 1 chain 0.0471 0.482 0.482
Trypanosoma cruzi DNA topoisomerase II, putative 0.0041 0.0323 0.0385
Loa Loa (eye worm) melatonin receptor type 1A 0.0059 0.0511 0.092
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0393 0.0708
Brugia malayi Sulfatase family protein 0.0028 0.0182 0.0189
Echinococcus multilocularis DNA mismatch repair protein Mlh1 0.002 0.0103 0.0103
Toxoplasma gondii sugar transporter ST2 0.0015 0.0046 0.0047
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0185 0.0192
Echinococcus multilocularis cpg binding protein 0.0032 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Brugia malayi ecdysone receptor 0.0025 0.0156 0.0162
Echinococcus granulosus Tubulin beta 2C chain 0.0471 0.482 0.482
Brugia malayi Protein kinase domain containing protein 0.0013 0.003 0.0031
Echinococcus multilocularis heat shock protein 90 0.0231 0.2313 0.2313
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Onchocerca volvulus 0.0015 0.0046 0.0068
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0091 0.0091
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0102 0.0059
Schistosoma mansoni Smad4 0.0018 0.0076 0.0081
Loa Loa (eye worm) hypothetical protein 0.0126 0.1215 0.2189
Schistosoma mansoni tar DNA-binding protein 0.0262 0.2629 0.2834
Brugia malayi GnHR receptor homolog 0.0059 0.0511 0.0531
Trypanosoma brucei alpha tubulin 0.0356 0.3619 0.4761
Leishmania major geranylgeranyltransferase, putative 0.002 0.0102 0.0095
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0036 0.0268 0.0494
Loa Loa (eye worm) hypothetical protein 0.0384 0.3911 0.7045
Leishmania major beta tubulin 0.0471 0.482 0.6538
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0041 0.0323 0.1168
Trypanosoma brucei glucose transporter, putative 0.0032 0.0231 0.0263
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0013 0.003 0.003
Onchocerca volvulus 0.0013 0.003 0.0039
Brugia malayi Peptidase family C54 containing protein 0.0069 0.061 0.0635
Loa Loa (eye worm) hypothetical protein 0.0083 0.0766 0.1379
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.042 0.0437
Schistosoma mansoni survival motor neuron protein 0.005 0.042 0.0452
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0019 0.0091 0.0091
Echinococcus multilocularis ubiquitin 0.0011 0.001 0.001
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0056 0.0474 0.0474
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0083 0.0766 0.0766
Leishmania major beta tubulin 0.0471 0.482 0.6538
Brugia malayi putative neuropeptide receptor NPR1 0.0059 0.0511 0.0531
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Schistosoma mansoni tubulin subunit beta 0.0471 0.482 0.5196
Mycobacterium ulcerans cell division protein FtsZ 0.0111 0.1051 0.4091
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0225 0.2247 0.2742
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0156 0.0168
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0056 0.0474 0.0474
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0043 0.0339 0.0339
Giardia lamblia Alpha-tubulin 0.0356 0.3619 0.4431
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Loa Loa (eye worm) hypothetical protein 0.0028 0.0182 0.0328
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.003 0.0054
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.002 0.0102 0.0106
Giardia lamblia Hypothetical protein 0.0028 0.0182 0.0222
Schistosoma mansoni amine GPCR 0.0059 0.0511 0.055
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0111 0.1051 0.2166
Giardia lamblia Pms1-like protein 0.0041 0.0323 0.0394
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0252 0.2524 0.3402
Leishmania major eukaryotic translation initiation factor-like 0.0036 0.027 0.0324
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0113 0.1078 0.1078
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0036 0.0268 0.0313
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0059 0.0511 0.0511
Onchocerca volvulus 0.0015 0.0046 0.0068
Brugia malayi larval opioid receptor 0.0059 0.0511 0.0531
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0013 0.0032 0.0046
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.002 0.0102 0.0193
Echinococcus multilocularis endoplasmin 0.0252 0.2524 0.2524
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0393 0.0409
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Brugia malayi SH2 domain containing protein 0.0013 0.003 0.0031
Onchocerca volvulus 0.0144 0.1403 0.2641
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0046 0.0075
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0245 0.246 0.4432
Leishmania major farnesyltransferase beta subunit 0.002 0.0102 0.0095
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0041 0.0323 0.0608
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0155 0.0302
Schistosoma mansoni alpha-1 adrenergic receptor 0.0059 0.0511 0.055
Trypanosoma brucei beta tubulin 0.0471 0.482 0.6356
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0228 0.0454
Onchocerca volvulus 0.0059 0.0511 0.095
Loa Loa (eye worm) hypothetical protein 0.0028 0.0188 0.0338
Schistosoma mansoni neuropeptide receptor 0.0059 0.0511 0.055
Schistosoma mansoni tyrosine kinase 0.035 0.3549 0.3826
Echinococcus multilocularis protocadherin 11 0.0018 0.008 0.008
Onchocerca volvulus 0.0059 0.0511 0.095
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Brugia malayi Tubulin beta chain 0.0144 0.1403 0.1461
Onchocerca volvulus 0.0014 0.0037 0.0052
Loa Loa (eye worm) TK protein kinase 0.0038 0.0293 0.0528
Brugia malayi Endoplasmin precursor 0.0273 0.2744 0.2858
Echinococcus multilocularis g protein coupled receptor 0.0059 0.0511 0.0511
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0028 0.0182 0.0327
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0059 0.0511 0.092
Schistosoma mansoni hypothetical protein 0.0018 0.008 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0036 0.0268 0.0268
Echinococcus granulosus solute carrier family 22 0.0015 0.0046 0.0046
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Leishmania major beta tubulin 0.0471 0.482 0.6538
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0041 0.0323 0.0323
Loa Loa (eye worm) endoplasmin 0.0273 0.2744 0.4943
Onchocerca volvulus 0.0059 0.0511 0.095
Trypanosoma cruzi DNA topoisomerase II, putative 0.0041 0.0323 0.0385
Loa Loa (eye worm) TAR-binding protein 0.0262 0.2629 0.4736
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Schistosoma mansoni hypothetical protein 0.0153 0.1491 0.1606
Toxoplasma gondii heat shock protein 90, putative 0.0273 0.2744 0.2847
Schistosoma mansoni glucose transporter 0.0015 0.0046 0.0049
Toxoplasma gondii facilitative glucose transporter GT1 0.0104 0.0984 0.102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0053 0.0452 0.0814
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.0067
Echinococcus granulosus neuropeptide receptor 0.0059 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Brugia malayi hypothetical protein 0.0384 0.3911 0.4073
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0231 0.0263
Brugia malayi Carboxylesterase family protein 0.0013 0.0032 0.0032
Echinococcus granulosus tyrosine protein kinase Blk 0.0047 0.0385 0.0385
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0091 0.0091
Schistosoma mansoni tyrosine kinase 0.0056 0.0474 0.0511
Brugia malayi sulfakinin receptor protein 0.0059 0.0511 0.0531
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0312 0.0628
Loa Loa (eye worm) hypothetical protein 0.0015 0.0045 0.008
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Leishmania major mismatch repair protein PMS1, putative,mismatch repair protein 0.002 0.0103 0.0096
Trypanosoma brucei Heat shock protein 83, putative 0.0273 0.2744 0.36
Onchocerca volvulus 0.0015 0.0046 0.0068
Plasmodium falciparum DNA mismatch repair protein MLH 0.002 0.0103 0.0106
Echinococcus granulosus voltage gated potassium channel 0.0012 0.0022 0.0022
Trypanosoma brucei protein farnesyltransferase beta subunit 0.002 0.0102 0.0093
Trichomonas vaginalis tubulin gamma chain, putative 0.0111 0.1051 0.2166
Echinococcus granulosus tyrosine protein kinase shark 0.0013 0.003 0.003
Schistosoma mansoni tubulin subunit gamma 0.0255 0.2562 0.2762
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0053 0.0452 0.0452
Echinococcus granulosus cysteine protease atg4b 0.0069 0.061 0.061
Loa Loa (eye worm) alpha-tubulin 0.0356 0.3619 0.652
Onchocerca volvulus 0.0014 0.0037 0.0052
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0059 0.0511 0.0511
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0091 0.0163
Loa Loa (eye worm) hypothetical protein 0.0031 0.0214 0.0386
Echinococcus granulosus DNA mismatch repair protein Mlh1 0.002 0.0103 0.0103
Entamoeba histolytica tubulin gamma chain 0.0255 0.2562 0.3129
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0036 0.027 0.027
Brugia malayi Isocitrate dehydrogenase 0.0036 0.0268 0.0279
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0356 0.3619 0.7504
Loa Loa (eye worm) hypothetical protein 0.0041 0.0323 0.0581
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0091 0.0094
Trichomonas vaginalis set domain proteins, putative 0.022 0.2192 0.4535
Schistosoma mansoni opsin-like receptor 0.0059 0.0511 0.055
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0059 0.0511 0.0531
Schistosoma mansoni smad1 5 8 and 0.0018 0.0076 0.0081
Schistosoma mansoni tubulin subunit beta 0.0471 0.482 0.5196
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0027 0.0172 0.0191
Brugia malayi Dopamine receptor protein 1 0.0059 0.0511 0.0531
Loa Loa (eye worm) hypothetical protein 0.018 0.1779 0.3205
Onchocerca volvulus 0.0015 0.0046 0.0068
Loa Loa (eye worm) G-protein coupled receptor 0.0059 0.0511 0.092
Echinococcus granulosus nAChR subunit 0.0019 0.0091 0.0091
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0069 0.061 0.1248
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0189 0.1869 0.1869
Brugia malayi Tubulin alpha chain 0.0356 0.3619 0.3769
Onchocerca volvulus 0.0025 0.0156 0.0278
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0188 0.0195
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0139 0.0169
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0048 0.0392 0.0392
Echinococcus multilocularis X box binding protein 1 0.0568 0.5835 0.5835
Trichomonas vaginalis tubulin gamma chain, putative 0.0255 0.2562 0.5306
Treponema pallidum sodium- and chloride- dependent transporter 0.0281 0.2836 1
Schistosoma mansoni hypothetical protein 0.0015 0.0048 0.0051
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0036 0.027 0.0315
Echinococcus granulosus heat shock protein 0.0273 0.2744 0.2744
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0392 0.0422
Echinococcus multilocularis geminin 0.0897 0.9276 0.9276
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0019 0.0091 0.0094
Brugia malayi hypothetical protein 0.0015 0.0046 0.0047
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0053 0.0452 0.0486
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0059 0.0511 0.055
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0059 0.0511 0.0511
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0286 0.0575
Brugia malayi G protein-coupled receptor 0.0059 0.0511 0.0531
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0036 0.0268 0.0268
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0227 0.0235
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0019 0.0091 0.0094
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0068 0.007
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0156 0.0156
Leishmania major beta tubulin 0.0471 0.482 0.6538
Loa Loa (eye worm) beta-tubulin 0.0471 0.482 0.8684
Brugia malayi hypothetical protein 0.0515 0.5284 0.5503
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0001 0.00000000005127
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0041 0.0323 0.0385
Echinococcus granulosus biogenic amine 5HT receptor 0.0059 0.0511 0.0511
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0056 0.0474 0.0474
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0091 0.0163
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0041 0.0323 0.0608
Onchocerca volvulus 0.0015 0.0046 0.0068
Trypanosoma cruzi tubulin delta chain 0.0111 0.1051 0.1353
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0286 0.0339
Onchocerca volvulus 0.0013 0.003 0.0039
Brugia malayi Calcitonin receptor-like protein seb-1 0.0264 0.2653 0.2762
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0156 0.0156
Echinococcus granulosus MORC family CW type zinc finger protein 2B 0.002 0.0103 0.0103
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0046 0.0047
Brugia malayi MH2 domain containing protein 0.0018 0.0076 0.0078
Loa Loa (eye worm) hypothetical protein 0.0025 0.0156 0.0281
Schistosoma mansoni amine GPCR 0.0059 0.0511 0.055
Brugia malayi hypothetical protein 0.0059 0.0511 0.0531
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0022 0.0119 0.0119
Leishmania major small ubiquitin protein, putative 0.0032 0.0228 0.0267
Schistosoma mansoni smad1 5 8 and 0.0018 0.0076 0.0081
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Echinococcus granulosus heat shock protein 90 0.0231 0.2313 0.2313
Brugia malayi Smad1 0.0018 0.0076 0.0078
Onchocerca volvulus 0.0059 0.0511 0.095
Onchocerca volvulus 0.0019 0.0091 0.0154
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0059 0.0511 0.0511
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0231 0.2313 0.2313
Mycobacterium ulcerans sulfatase 0.0028 0.0182 0.0603
Brugia malayi Sugar transporter family protein 0.0015 0.0046 0.0047
Loa Loa (eye worm) hypothetical protein 0.0393 0.4002 0.721
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus granulosus solute carrier family 22 0.0015 0.0046 0.0046
Plasmodium falciparum transporter, putative 0.0048 0.0392 0.0406
Plasmodium vivax delta tubulin, putative 0.0111 0.1051 0.1049
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0012 0.0022 0.0022
Loa Loa (eye worm) RNA binding protein 0.0262 0.2629 0.4736
Loa Loa (eye worm) hypothetical protein 0.0013 0.0024 0.0043
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.0067
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0185 0.0146
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0102 0.0184
Loa Loa (eye worm) hypothetical protein 0.0025 0.0156 0.0281
Brugia malayi GoLoco motif family protein 0.0013 0.0024 0.0025
Mycobacterium ulcerans sugar transporter 0.0015 0.0046 0.0056
Loa Loa (eye worm) latrophilin receptor protein 2 0.0083 0.0766 0.1379
Entamoeba histolytica heat shock protein 90, putative 0.0273 0.2744 0.3352
Echinococcus granulosus growth factor receptor bound protein 2 0.0017 0.0073 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Loa Loa (eye worm) hypothetical protein 0.0013 0.0032 0.0057
Trypanosoma cruzi epsilon tubulin, putative 0.0255 0.2562 0.3358
Brugia malayi Latrophilin receptor protein 2 0.0083 0.0766 0.0797
Schistosoma mansoni tyrosine kinase 0.0022 0.0119 0.0128
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0036 0.0268 0.0322
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0046 0.0075
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0188 0.0202
Brugia malayi Ubiquitin-like protein SMT3 0.0032 0.0228 0.0237
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0041 0.0323 0.0594
Giardia lamblia Epsilon tubulin 0.0111 0.1051 0.1287
Echinococcus granulosus 7tm_1 domain containing protein 0.0059 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0018 0.008 0.0145
Onchocerca volvulus 0.0019 0.0091 0.0154
Schistosoma mansoni sugar transporter 0.0015 0.0046 0.0049
Loa Loa (eye worm) RecQ helicase 0.0025 0.0155 0.0279
Toxoplasma gondii corepressor complex CRC230 0.002 0.0103 0.0106
Brugia malayi kinase, mitochondrial precursor 0.0041 0.0323 0.0336
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.002 0.0102 0.0114
Onchocerca volvulus 0.0015 0.0046 0.0068
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Onchocerca volvulus 0.0059 0.0511 0.095
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0156 0.0162
Brugia malayi hypothetical protein 0.0018 0.008 0.0083
Onchocerca volvulus 0.0048 0.0392 0.0725
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0068 0.0122
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0511 0.055
Plasmodium falciparum heat shock protein 90, putative 0.0153 0.1496 0.1552
Leishmania major glucose transporter, lmgt1 0.0032 0.0231 0.0271
Trypanosoma cruzi heat shock protein 85, putative 0.0231 0.2313 0.3028
Brugia malayi RNA recognition motif domain containing protein 0.0262 0.2629 0.2738
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0156 0.0156
Schistosoma mansoni biogenic amine (5HT) receptor 0.0201 0.1993 0.2148
Schistosoma mansoni neuropeptide F-like receptor 0.0059 0.0511 0.055
Schistosoma mansoni neuropeptide f receptor 76f 0.0059 0.0511 0.055
Trypanosoma brucei glucose transporter, putative 0.0032 0.0231 0.0263
Schistosoma mansoni growth factor receptor-bound protein 0.0017 0.0073 0.0078
Schistosoma mansoni smad1 5 8 and 0.0018 0.0076 0.0081
Mycobacterium ulcerans two component regulator - sensor kinase 0.0041 0.0323 0.1168
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus multilocularis neuropeptide receptor 0.0059 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Schistosoma mansoni importin beta-1 0.0032 0.0227 0.0245
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0155 0.0302
Loa Loa (eye worm) neuropeptide F receptor 0.0059 0.0511 0.092
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0041 0.0323 0.1168
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0286 0.0308
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0059 0.0511 0.0531
Trypanosoma brucei heat shock protein, putative 0.0273 0.2744 0.36
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0511 0.055
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0164 0.0321
Loa Loa (eye worm) tubulin gamma chain 0.0255 0.2562 0.4616
Brugia malayi excitatory GABA receptor EXP-1A 0.0019 0.0091 0.0094
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.002 0.0102 0.0102
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0393 0.0393
Plasmodium falciparum geranylgeranyltransferase, putative 0.002 0.0102 0.0106
Onchocerca volvulus 0.0018 0.008 0.0134
Echinococcus granulosus tubulin alpha 1C chain 0.0356 0.3619 0.3619
Echinococcus multilocularis hypothetical protein 0.0356 0.3619 0.3619
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0056 0.0474 0.0474
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0188 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Onchocerca volvulus 0.0031 0.022 0.04
Schistosoma mansoni hypothetical protein 0.0059 0.0511 0.055
Loa Loa (eye worm) hypothetical protein 0.0032 0.0227 0.041
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0036 0.027 0.0279
Plasmodium vivax tubulin epsilon chain, putative 0.0255 0.2562 0.2624
Echinococcus granulosus lamin 0.0031 0.022 0.022
Schistosoma mansoni tyrosine kinase 0.0013 0.003 0.0032
Schistosoma mansoni hypothetical protein 0.0059 0.0511 0.055
Echinococcus multilocularis ccaat enhancer binding protein delta ccaat enhancer binding protein beta 0.0018 0.008 0.008
Echinococcus multilocularis tubulin alpha 3 chain 0.0356 0.3619 0.3619
Giardia lamblia Alpha-tubulin 0.0356 0.3619 0.4431
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0252 0.2524 0.5203
Trichomonas vaginalis tubulin beta chain, putative 0.0356 0.3619 0.7504
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0069 0.061 0.1099
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0048 0.0392 0.0422
Echinococcus multilocularis fmrfamide receptor 0.0059 0.0511 0.0511
Schistosoma mansoni neuropeptide receptor 0.0059 0.0511 0.055
Giardia lamblia Prenyltransferase 0.002 0.0102 0.0125
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0227 0.0259
Onchocerca volvulus 0.0013 0.003 0.0039
Echinococcus multilocularis tubulin alpha 0.0255 0.2562 0.2562
Leishmania major gamma-tubulin 0.0255 0.2562 0.3454
Onchocerca volvulus 0.0018 0.008 0.0134
Schistosoma mansoni sodium/chloride dependent transporter 0.0048 0.0392 0.0422
Brugia malayi major facilitator superfamily protein 0.0015 0.0046 0.0047
Echinococcus granulosus tyrosine protein kinase Src64B 0.0056 0.0474 0.0474
Toxoplasma gondii sugar transporter ST3 0.0015 0.0046 0.0047
Leishmania major alpha tubulin 0.0356 0.3619 0.4898
Brugia malayi hypothetical protein 0.0928 0.9601 1
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Echinococcus multilocularis tar DNA binding protein 0.0262 0.2629 0.2629
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0053 0.0452 0.047
Plasmodium falciparum alpha tubulin 1 0.0356 0.3619 0.3755
Echinococcus granulosus 7TM GPCR rhodopsin 0.0059 0.0511 0.0511
Schistosoma mansoni amine GPCR 0.0059 0.0511 0.055
Echinococcus multilocularis lamin 0.0031 0.022 0.022
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0185 0.0192
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0046 0.0046
Toxoplasma gondii alpha tubulin TUBA1 0.0356 0.3619 0.3755
Schistosoma mansoni tubulin subunit beta 0.0471 0.482 0.5196
Echinococcus multilocularis epidermal growth factor receptor 0.0189 0.1869 0.1869
Trypanosoma cruzi heat shock protein, putative 0.0173 0.1707 0.2222
Giardia lamblia Gamma tubulin 0.0255 0.2562 0.3137
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0511 0.055
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0015 0.0045 0.008
Plasmodium vivax heat shock protein, putative 0.0931 0.9638 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0059 0.0511 0.0511
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0164 0.0321
Schistosoma mansoni alpha tubulin 0.0356 0.3619 0.3902
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Echinococcus multilocularis tubulin gamma 1 chain 0.0255 0.2562 0.2562
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0173 0.1707 0.1707
Schistosoma mansoni tyrosine kinase 0.0189 0.1869 0.2014
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0091 0.0091
Treponema pallidum cell division protein FtsZ 0.0111 0.1051 0.3471
Leishmania major beta tubulin 0.0471 0.482 0.6538
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0053 0.0452 0.0452
Loa Loa (eye worm) hypothetical protein 0.0031 0.022 0.0397
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0048 0.0392 0.0392
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Echinococcus multilocularis serotonin receptor 0.0201 0.1993 0.1993
Schistosoma mansoni heat shock protein 0.0273 0.2744 0.2958
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0041 0.0323 0.0385
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0511 0.055
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0041 0.0323 0.0805
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0056 0.0474 0.0474
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0139 0.025
Giardia lamblia Rab geranylgeranyltransferase 0.002 0.0102 0.0125
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0264 0.2653 0.2762
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0043 0.0341 0.0615
Echinococcus granulosus dnaJ subfamily B 0.0428 0.437 0.437
Leishmania major delta tubulin, putative 0.0111 0.1051 0.1391
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0281 0.2836 0.2953
Trypanosoma cruzi small ubiquitin protein, putative 0.0032 0.0228 0.0259
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Echinococcus multilocularis dnaJ subfamily B 0.0428 0.437 0.437
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0036 0.027 0.0319
Loa Loa (eye worm) hypothetical protein 0.0048 0.0392 0.0706
Schistosoma mansoni thyroid hormone receptor 0.0053 0.0452 0.0486
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.0086
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0053 0.0452 0.0486
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0392 0.0422
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0091 0.0091
Brugia malayi TAR-binding protein 0.0262 0.2629 0.2738
Schistosoma mansoni hypothetical protein 0.0568 0.5835 0.629
Trichomonas vaginalis tubulin epsilon chain, putative 0.0356 0.3619 0.7504
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0231 0.0459
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0059 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0048 0.0392 0.0706
Loa Loa (eye worm) hypothetical protein 0.0247 0.2481 0.447
Brugia malayi Dopamine receptor protein 2 0.0059 0.0511 0.0531
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0032 0.0033
Brugia malayi hypothetical protein 0.0018 0.0081 0.0084
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0059 0.0511 0.0511
Brugia malayi Cation transporter family protein 0.0019 0.0091 0.0094
Entamoeba histolytica protein kinase, putative 0.0038 0.0293 0.0348
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0041 0.0323 0.1168
Echinococcus multilocularis tyrosine kinase 0.0013 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Entamoeba histolytica heat shock protein 90, putative 0.0273 0.2744 0.3352
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0036 0.0268 0.0313
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0091 0.0091
Brugia malayi RNA, U transporter 1 0.0091 0.0846 0.088
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0091 0.0094
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0227 0.0227
Brugia malayi Protein kinase domain containing protein 0.0013 0.003 0.0031
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0068 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0046 0.0075
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.002 0.0102 0.011
Trypanosoma cruzi mismatch repair protein MLH1, putative 0.002 0.0103 0.0093
Loa Loa (eye worm) G-protein coupled receptor 0.0059 0.0511 0.092
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Toxoplasma gondii heat shock protein HSP90 0.0273 0.2744 0.2847
Trypanosoma brucei glucose transporter 2A 0.0032 0.0231 0.0263
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0019 0.0091 0.0163
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.0984 0.0984
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0046 0.0046
Echinococcus granulosus allatostatin A receptor 0.0059 0.0511 0.0511
Schistosoma mansoni tubulin subunit alpha 0.0356 0.3619 0.3902
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0091 0.0091
Trypanosoma brucei small ubiquitin-related modifier 0.0032 0.0228 0.0259
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0019 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0053 0.0452 0.0452
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0053 0.0452 0.0814
Trichomonas vaginalis heat shock protein, putative 0.0252 0.2524 0.5227
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0139 0.0143
Echinococcus granulosus para nitrobenzyl esterase 0.0013 0.0032 0.0032
Schistosoma mansoni acetylcholinesterase 0.0013 0.0032 0.0033
Schistosoma mansoni neuropeptide F-like receptor 0.0059 0.0511 0.055
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0041 0.0323 0.0651
Echinococcus multilocularis neuropeptide s receptor 0.0966 1 1
Onchocerca volvulus 0.0015 0.0046 0.0068
Echinococcus granulosus tar DNA binding protein 0.0262 0.2629 0.2629
Schistosoma mansoni BC026374 protein (S09 family) 0.0013 0.0032 0.0033
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0079 0.0717 0.0773
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Brugia malayi hypothetical protein 0.0059 0.0511 0.0531
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0076 0.0076
Trichomonas vaginalis tubulin epsilon chain, putative 0.0356 0.3619 0.7504
Brugia malayi Sex muscle abnormal protein 5 0.0017 0.0073 0.0076
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0028 0.0188 0.0202
Schistosoma mansoni tyrosine kinase 0.0113 0.1078 0.1162
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0059 0.0511 0.0511
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0048 0.0392 0.0392
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0053 0.0452 0.0486
Echinococcus multilocularis cyclic AMP responsive element binding protein 0.0018 0.008 0.008
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0123 0.0127
Mycobacterium ulcerans heat shock protein 90 0.0252 0.2524 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0286 0.0286
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.0984 0.0984
Leishmania major glucose transporter, lmgt2 0.0032 0.0231 0.0271
Brugia malayi nuclear receptor NHR-88 0.0053 0.0452 0.047
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Loa Loa (eye worm) hypothetical protein 0.0025 0.0156 0.0281
Brugia malayi Serotonin receptor 0.0059 0.0511 0.0531
Brugia malayi Protein kinase domain containing protein 0.0013 0.003 0.0031
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0059 0.0511 0.092
Leishmania major lanosterol synthase, putative 0.0713 0.7356 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0053 0.0452 0.047
Plasmodium vivax farnesyltransferase beta subunit, putative 0.002 0.0102 0.0059
Trypanosoma brucei developmentally regulated phosphoprotein 0.0041 0.0323 0.0385
Leishmania major alpha tubulin 0.0356 0.3619 0.4898
Brugia malayi Tyrosine-protein kinase abl-1 0.0022 0.0119 0.0124
Echinococcus granulosus neuropeptides capa receptor 0.0059 0.0511 0.0511
Leishmania major beta tubulin 0.0471 0.482 0.6538
Echinococcus multilocularis tubulin alpha chain 0.0356 0.3619 0.3619
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0156 0.0156
Echinococcus multilocularis Smad4 0.0018 0.0076 0.0076
Echinococcus granulosus tyrosine protein kinase Fyn 0.0056 0.0474 0.0474
Echinococcus multilocularis beta tubulin 0.0471 0.482 0.482
Loa Loa (eye worm) Smad1 0.0018 0.0076 0.0136
Echinococcus granulosus protocadherin 11 0.0018 0.008 0.008
Schistosoma mansoni adenoreceptor 0.0059 0.0511 0.055
Loa Loa (eye worm) neuropeptide F receptor 0.0059 0.0511 0.092
Brugia malayi Sugar transporter family protein 0.0104 0.0984 0.1024
Echinococcus multilocularis neuroligin 0.0013 0.0032 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0053 0.0452 0.047
Leishmania major alpha tubulin 0.0356 0.3619 0.4898
Plasmodium falciparum DNA topoisomerase 2 0.0041 0.0323 0.0334
Brugia malayi hypothetical protein 0.0059 0.0511 0.0531
Loa Loa (eye worm) hypothetical protein 0.0281 0.2836 0.5108
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0102 0.0106
Brugia malayi Carboxylesterase family protein 0.0079 0.0717 0.0747
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0188 0.0202
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0041 0.0323 0.0323
Echinococcus granulosus tyrosine protein kinase HCK 0.0038 0.0293 0.0293
Echinococcus multilocularis serotonin receptor 0.0201 0.1993 0.1993
Leishmania major developmentally regulated phosphoprotein-like protein 0.0041 0.0323 0.0396
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0041 0.0323 0.0336
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0393 0.0423
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.007 0.0025
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0059 0.0511 0.055
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0286 0.0298
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0111 0.1051 0.4058
Echinococcus granulosus carboxylesterase 5A 0.0079 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0028 0.0188 0.0338
Toxoplasma gondii hypothetical protein 0.0048 0.0392 0.0406
Onchocerca volvulus 0.0019 0.0091 0.0154
Loa Loa (eye worm) translation initiation factor 4E 0.0036 0.027 0.0486
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0059 0.0511 0.0511
Loa Loa (eye worm) solute carrier family 6 member 4 0.0281 0.2836 0.5108
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0019 0.0091 0.0091
Echinococcus multilocularis solute carrier family 22 0.0015 0.0046 0.0046
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0028 0.0182 0.0358
Trypanosoma brucei heat shock protein, putative 0.0273 0.2744 0.36
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0155 0.0161
Brugia malayi hypothetical protein 0.0059 0.0511 0.0531
Loa Loa (eye worm) hypothetical protein 0.0028 0.0182 0.0328
Entamoeba histolytica Ran family GTPase 0.0024 0.0139 0.0158
Echinococcus granulosus Smad4 0.0018 0.0076 0.0076
Schistosoma mansoni transcription factor LCR-F1 0.0153 0.1491 0.1606
Echinococcus multilocularis Tubulin beta 2C chain 0.0471 0.482 0.482
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.002 0.0102 0.0193
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Brugia malayi MH1 domain containing protein 0.0018 0.0076 0.0078
Echinococcus granulosus endoplasmin 0.0252 0.2524 0.2524
Onchocerca volvulus 0.0048 0.0392 0.0725
Echinococcus multilocularis acetylcholinesterase 0.0079 0.0717 0.0717
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0102 0.0193
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Echinococcus granulosus tyrosine protein kinase Src42A 0.0043 0.0339 0.0339
Echinococcus multilocularis protocadherin 11 0.0018 0.008 0.008
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0069 0.061 0.0789
Echinococcus granulosus tyrosine protein kinase ABL1 0.0013 0.003 0.003
Loa Loa (eye worm) TK/ALK protein kinase 0.0019 0.0094 0.017
Schistosoma mansoni sugar transporter 0.0015 0.0046 0.0049
Brugia malayi heat shock protein 90 0.0273 0.2744 0.2858
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0083 0.0766 0.0766
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0053 0.0452 0.047
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.002 0.0102 0.0106
Schistosoma mansoni pyruvate dehydrogenase 0.0041 0.0323 0.0347
Echinococcus multilocularis tubulin alpha chain 0.0356 0.3619 0.3619
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0102 0.0193
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0069 0.061 0.0657
Loa Loa (eye worm) hypothetical protein 0.0025 0.0156 0.0281
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0041 0.0323 0.1168
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0028 0.0182 0.0358
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0048 0.0392 1
Echinococcus multilocularis c src tyrosine kinase 0.0022 0.0119 0.0119
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0012 0.0022 0.0023
Echinococcus multilocularis Tubulin alpha 1 chain 0.0356 0.3619 0.3619
Schistosoma mansoni tyrosine kinase 0.0185 0.1823 0.1964
Loa Loa (eye worm) hypothetical protein 0.0013 0.0032 0.0057
Schistosoma mansoni hypothetical protein 0.0428 0.437 0.4711
Giardia lamblia Hexose transporter 0.0015 0.0046 0.0055
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0144 0.1403 0.2896
Echinococcus granulosus tubulin subunit beta 0.0471 0.482 0.482
Trichomonas vaginalis tubulin alpha chain, putative 0.0144 0.1403 0.2896
Echinococcus multilocularis tubulin alpha chain 0.0356 0.3619 0.3619
Brugia malayi alpha-tubulin 0.0356 0.3619 0.3769
Leishmania major beta tubulin 0.0471 0.482 0.6538
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0033 0.0048
Trichomonas vaginalis tubulin gamma chain, putative 0.0255 0.2562 0.5306
Echinococcus multilocularis conserved hypothetical protein 0.0803 0.8293 0.8293
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0036 0.0268 0.0313
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0059 0.0511 0.0511
Entamoeba histolytica tubulin family protein 0.0471 0.482 0.5897
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0286 0.0337
Schistosoma mansoni hypothetical protein 0.018 0.1779 0.1918
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0041 0.0323 0.0608
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0091 0.0094
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.002 0.0102 0.0114
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.002 0.0102 0.0093
Brugia malayi hypothetical protein 0.0025 0.0156 0.0162
Trichomonas vaginalis tubulin beta chain, putative 0.0356 0.3619 0.7504
Mycobacterium ulcerans two component sensor kinase MprB 0.0041 0.0323 0.1168
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0036 0.027 0.0324
Echinococcus multilocularis nAChR subunit 0.0019 0.0091 0.0091
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0043 0.0341 0.0355
Loa Loa (eye worm) hypothetical protein 0.0025 0.0156 0.0281
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0018 0.008 0.008
Loa Loa (eye worm) TK protein kinase 0.0047 0.0385 0.0694
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0207 0.0372
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0041 0.0323 0.0651
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Trypanosoma brucei alpha tubulin 0.0356 0.3619 0.4761
Onchocerca volvulus 0.0059 0.0511 0.095
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0156 0.0168
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.003 0.0054
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0053 0.0452 0.0452
Trichomonas vaginalis tubulin gamma chain, putative 0.0471 0.482 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0153 0.1491 0.1491
Schistosoma mansoni hypothetical protein 0.0342 0.3472 0.3742
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0393 0.0423
Echinococcus multilocularis allatostatin A receptor 0.0059 0.0511 0.0511
Echinococcus multilocularis MAM 0.0015 0.0048 0.0048
Brugia malayi hypothetical protein 0.0059 0.0511 0.0531
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0156 0.0281
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0393 0.0423
Schistosoma mansoni tyrosine kinase 0.0056 0.0474 0.0511
Leishmania major eukaryotic translation initiation factor-like protein 0.0036 0.027 0.0324
Trypanosoma brucei glucose transporter, putative 0.0032 0.0231 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0059 0.0511 0.055
Schistosoma mansoni tyrosine kinase 0.0185 0.1823 0.1964
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus granulosus tm gpcr rhodopsin 0.0059 0.0511 0.0511
Brugia malayi hypothetical protein 0.0153 0.1491 0.1552
Schistosoma mansoni heat shock protein 0.0173 0.1707 0.1839
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0033 0.0028
Echinococcus granulosus neuroligin 0.0013 0.0032 0.0032
Plasmodium falciparum tubulin gamma chain 0.0255 0.2562 0.2658
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0091 0.0094
Brugia malayi hypothetical protein 0.0013 0.0032 0.0032
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0452 0.0452
Trypanosoma brucei mismatch repair protein PMS1, putative 0.002 0.0103 0.0093
Schistosoma mansoni thyrotroph embryonic factor related 0.0018 0.008 0.0086
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Brugia malayi Protein kinase domain containing protein 0.0013 0.003 0.0031
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Brugia malayi SH2 domain containing protein 0.0013 0.003 0.0031
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0153 0.1491 0.1491
Trichomonas vaginalis heat shock protein, putative 0.0194 0.1927 0.3985
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0139 0.0139
Echinococcus multilocularis isocitrate dehydrogenase 0.0036 0.0268 0.0268
Echinococcus granulosus tubulin alpha 0.0255 0.2562 0.2562
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0036 0.027 0.0541
Brugia malayi tubulin alpha chain - mouse 0.0356 0.3619 0.3769
Plasmodium vivax heat shock protein 86, putative 0.0273 0.2744 0.2813
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0041 0.0323 0.0336
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Trypanosoma brucei epsilon tubulin 0.0255 0.2562 0.3358
Schistosoma mansoni retinoic acid receptor RXR 0.0053 0.0452 0.0486
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0076 0.0136
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Onchocerca volvulus 0.0048 0.0392 0.0725
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0028 0.0188 0.0188
Brugia malayi Cell division protein ftsZ 0.0111 0.1051 0.1095
Loa Loa (eye worm) hypothetical protein 0.0541 0.5551 1
Giardia lamblia DNA repair protein RAD52 0.0791 0.8167 1
Onchocerca volvulus 0.0059 0.0511 0.095
Brugia malayi Carboxylesterase family protein 0.0013 0.0032 0.0032
Echinococcus granulosus serotonin transporter 0.0281 0.2836 0.2836
Leishmania major alpha tubulin 0.0356 0.3619 0.4898
Entamoeba histolytica peptidase, C54 family 0.0069 0.061 0.0736
Loa Loa (eye worm) hypothetical protein 0.002 0.0103 0.0185
Onchocerca volvulus 0.0059 0.0511 0.095
Echinococcus granulosus tubulin alpha 3 chain 0.0356 0.3619 0.3619
Plasmodium falciparum hexose transporter 0.0104 0.0984 0.102
Echinococcus granulosus heat shock protein 90 0.0273 0.2744 0.2744
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0139 0.0141
Trypanosoma brucei beta tubulin 0.0471 0.482 0.6356
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0059 0.0511 0.0531
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Plasmodium vivax endoplasmin, putative 0.0273 0.2744 0.2813
Leishmania major zeta tubulin, putative 0.0111 0.1051 0.1391
Onchocerca volvulus 0.0059 0.0511 0.095
Schistosoma mansoni hypothetical protein 0.0013 0.0024 0.0025
Giardia lamblia Mlh1-like protein 0.002 0.0103 0.0125
Schistosoma mansoni hypothetical protein 0.0083 0.0766 0.0825
Toxoplasma gondii DNA mismatch repair protein, C-terminal domain-containing protein 0.002 0.0103 0.0106
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0027 0.0172 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Schistosoma mansoni nuclear receptor 0.0025 0.0156 0.0168
Loa Loa (eye worm) hypothetical protein 0.0013 0.003 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.1051 0.2166
Echinococcus multilocularis tyrosine protein kinase Abl 0.0022 0.0119 0.0119
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0013 0.003 0.0025
Schistosoma mansoni neuroligin 3 (S09 family) 0.0013 0.0032 0.0033
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0053 0.0452 0.0486
Onchocerca volvulus 0.0059 0.0511 0.095
Loa Loa (eye worm) hypothetical protein 0.002 0.0102 0.0184
Schistosoma mansoni cpg binding protein 0.0032 0.0224 0.0241
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0041 0.0323 0.0608
Brugia malayi Cation transporter family protein 0.0019 0.0091 0.0094
Echinococcus granulosus tubulin alpha 1C chain 0.0356 0.3619 0.3619
Echinococcus granulosus histone lysine methyltransferase setb 0.0028 0.0188 0.0188
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.002 0.0102 0.0102
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0452 0.047
Onchocerca volvulus 0.0013 0.003 0.0039
Echinococcus granulosus sodium and chloride dependent glycine 0.0048 0.0392 0.0392
Echinococcus multilocularis voltage gated potassium channel 0.0012 0.0022 0.0022
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0392 0.0406
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0102 0.0093
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.002 0.0102 0.0114
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0027 0.0172 0.0185
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0019 0.0091 0.0091
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0041 0.0323 0.0334
Entamoeba histolytica hypothetical protein 0.0153 0.1491 0.1815
Echinococcus multilocularis tubulin delta chain 0.0111 0.1051 0.1051
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0018 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0018 0.008 0.0145
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0019 0.0091 0.0097
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.0086
Schistosoma mansoni DNA topoisomerase II 0.0041 0.0323 0.0347
Schistosoma mansoni sugar transporter 0.0015 0.0046 0.0049
Loa Loa (eye worm) hypothetical protein 0.0515 0.5284 0.9519
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Onchocerca volvulus 0.0059 0.0511 0.095
Plasmodium vivax SET domain protein, putative 0.0028 0.0188 0.0148
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0156 0.0281
Schistosoma mansoni tubulin subunit beta 0.0111 0.1051 0.1133
Schistosoma mansoni hypothetical protein 0.0059 0.0511 0.055
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0053 0.0452 0.047
Entamoeba histolytica hypothetical protein 0.0153 0.1491 0.1815
Trichomonas vaginalis tubulin epsilon chain, putative 0.0471 0.482 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0139 0.0097
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0312 0.0628
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0053 0.0452 0.0814
Echinococcus granulosus tubulin beta 4A class IVa 0.0471 0.482 0.482
Echinococcus multilocularis fmrfamide receptor 0.0059 0.0511 0.0511
Echinococcus granulosus tyrosine protein kinase Fyn 0.0056 0.0474 0.0474
Onchocerca volvulus Phospholipase A2 homolog 0.0509 0.5213 0.9864
Trypanosoma cruzi heat shock protein 85, putative 0.0273 0.2744 0.36
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0059 0.0511 0.055
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.0984 0.0984
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0048 0.0392 0.0706
Trypanosoma brucei glucose transporter, putative 0.0032 0.0231 0.0263
Trypanosoma brucei zeta tubulin, putative 0.0111 0.1051 0.1353
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0156 0.0156
Trypanosoma brucei sugar transporter, putative 0.0015 0.0046 0.0017
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.002 0.0102 0.0093
Trypanosoma cruzi mismatch repair protein MLH1, putative 0.002 0.0103 0.0093
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0059 0.0511 0.055
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.002 0.0102 0.0106
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0059 0.0511 0.0511
Leishmania major beta tubulin 0.0471 0.482 0.6538
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0022 0.0119 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0452 0.047
Echinococcus granulosus neuropeptides capa receptor 0.0059 0.0511 0.0511
Leishmania major hypothetical protein, conserved 0.0015 0.0046 0.0018
Mycobacterium ulcerans arylsulfatase AtsB 0.0028 0.0182 0.0603
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0032 0.0033
Brugia malayi beta-tubulin, identical 0.0471 0.482 0.502
Loa Loa (eye worm) hypothetical protein 0.0025 0.0156 0.0281
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.003 0.0054
Brugia malayi G protein-coupled receptor F59B2.13 0.0059 0.0511 0.0531
Echinococcus multilocularis Peptidase C54 0.0069 0.061 0.061
Brugia malayi tubulin alpha-2 chain 0.0356 0.3619 0.3769
Loa Loa (eye worm) hypothetical protein 0.0018 0.008 0.0145
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0286 0.0347
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0264 0.2653 0.4779
Brugia malayi hypothetical protein 0.0028 0.0188 0.0195
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0041 0.0323 0.0805
Echinococcus multilocularis sodium and chloride dependent glycine 0.0048 0.0392 0.0392
Echinococcus multilocularis neuropeptide Y receptor 0.0059 0.0511 0.0511
Schistosoma mansoni biogenic amine receptor 0.0059 0.0511 0.055
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0041 0.0323 0.0608
Loa Loa (eye worm) hypothetical protein 0.0037 0.0282 0.0508
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0019 0.0091 0.0163
Schistosoma mansoni amine GPCR 0.0059 0.0511 0.055
Trichomonas vaginalis tubulin beta chain, putative 0.0356 0.3619 0.7504
Loa Loa (eye worm) TK/ABL protein kinase 0.0013 0.003 0.0054
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Echinococcus granulosus X box binding protein 1 0.0568 0.5835 0.5835
Brugia malayi MH2 domain containing protein 0.0018 0.0076 0.0078
Echinococcus multilocularis acetylcholinesterase 0.0079 0.0717 0.0717
Brugia malayi nuclear receptor NHR-88 0.0025 0.0156 0.0162
Trypanosoma cruzi heat shock protein 85, putative 0.0273 0.2744 0.36
Entamoeba histolytica DNA mismatch repair protein PMS1, putative 0.002 0.0103 0.0114
Leishmania major hypothetical protein, conserved 0.0041 0.0323 0.0396
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0041 0.0323 0.0334
Echinococcus multilocularis Tubulin beta 2C chain 0.0471 0.482 0.482
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0111 0.1051 0.109
Mycobacterium leprae cell division protein FtsZ 0.0111 0.1051 0.331
Trichomonas vaginalis receptor histidine kinase, putative 0.0041 0.0323 0.0651
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0393 0.0393
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.002 0.0102 0.0184
Echinococcus multilocularis G protein signaling modulator 2 0.0013 0.0024 0.0024
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0091 0.0091
Loa Loa (eye worm) LGC-31 protein 0.0019 0.0091 0.0163
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.2481 0.2481
Brugia malayi Tachykinin-like peptides receptor 99D 0.0059 0.0511 0.0531
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0059 0.0511 0.0531
Brugia malayi hypothetical protein 0.0028 0.0182 0.0189
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0059 0.0511 0.095
Entamoeba histolytica tubulin family protein 0.0471 0.482 0.5897
Echinococcus granulosus tubulin alpha chain 0.0356 0.3619 0.3619
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0041 0.0323 0.1118
Loa Loa (eye worm) hypothetical protein 0.0025 0.0156 0.0281
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0059 0.0511 0.0511
Brugia malayi hypothetical protein 0.0059 0.0511 0.0531
Trypanosoma brucei tubulin gamma chain 0.0255 0.2562 0.3358
Loa Loa (eye worm) intermediate filament protein 0.0031 0.022 0.0397
Echinococcus granulosus peptide allatostatin:somatostatin 0.0059 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0025 0.0156 0.0281
Echinococcus multilocularis transcriptional factor nfil3:e4bp4 0.0018 0.008 0.008
Brugia malayi Protein kinase domain containing protein 0.0113 0.1078 0.1122
Echinococcus multilocularis Tubulin alpha 1 chain 0.0356 0.3619 0.3619
Loa Loa (eye worm) hypothetical protein 0.0048 0.0392 0.0706
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0342 0.3472 0.6254
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Trypanosoma cruzi alpha tubulin, putative 0.0356 0.3619 0.4761
Loa Loa (eye worm) hypothetical protein 0.0025 0.0156 0.0281
Onchocerca volvulus 0.0019 0.0091 0.0154
Trichomonas vaginalis mismatch repair protein Pms1 (mutL homolog) 0.002 0.0103 0.0194
Brugia malayi Carboxylesterase family protein 0.0079 0.0717 0.0747
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0231 0.0459
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.022 0.0229
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0059 0.0511 0.055
Echinococcus multilocularis g protein coupled receptor 0.0059 0.0511 0.0511
Loa Loa (eye worm) DR-78 0.0025 0.0156 0.0281
Echinococcus granulosus sex peptide receptor 0.0059 0.0511 0.0511
Trichomonas vaginalis tubulin alpha chain, putative 0.0255 0.2562 0.5306
Echinococcus granulosus beta tubulin 0.0471 0.482 0.482
Plasmodium falciparum importin beta, putative 0.0032 0.0227 0.0235
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Loa Loa (eye worm) transcription factor SMAD2 0.0258 0.2588 0.4661
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0015 0.0046 0.0047
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0041 0.0323 0.0594
Onchocerca volvulus 0.0013 0.0032 0.0042
Echinococcus multilocularis growth factor receptor bound protein 2 0.0017 0.0073 0.0073
Giardia lamblia Beta tubulin 0.0471 0.482 0.5902
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.0086
Echinococcus multilocularis G-protein coupled receptor, putative 0.0059 0.0511 0.0511
Echinococcus multilocularis NCK adaptor protein 0.0017 0.0073 0.0073
Echinococcus multilocularis smad 0.0018 0.0076 0.0076
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0046 0.0047
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0069 0.061 0.0767
Brugia malayi isocitrate dehydrogenase 0.0036 0.0268 0.0279
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Toxoplasma gondii beta tubulin 0.0471 0.482 0.5001
Loa Loa (eye worm) tubulin beta-1 chain 0.0471 0.482 0.8684
Trichomonas vaginalis tubulin beta chain, putative 0.0356 0.3619 0.7504
Echinococcus granulosus ubiquitin 0.0011 0.001 0.001
Leishmania major beta tubulin 0.0471 0.482 0.6538
Schistosoma mansoni lamin 0.0031 0.022 0.0237
Giardia lamblia Beta tubulin 0.0471 0.482 0.5902
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0286 0.0337
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0027 0.017 0.017
Echinococcus multilocularis snurportin 1 0.0342 0.3472 0.3472
Loa Loa (eye worm) bZIP transcription factor family protein 0.0018 0.008 0.0145
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0041 0.0323 0.0608
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.003 0.0054
Schistosoma mansoni tar DNA-binding protein 0.0262 0.2629 0.2834
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0156 0.0168
Brugia malayi hypothetical protein 0.0015 0.0046 0.0047
Trypanosoma brucei beta tubulin 0.0471 0.482 0.6356
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Trichomonas vaginalis heat shock protein, putative 0.0153 0.1496 0.309
Schistosoma mansoni ran 0.0024 0.0139 0.0149
Trypanosoma brucei tubulin delta chain 0.0111 0.1051 0.1353
Schistosoma mansoni hypothetical protein 0.0897 0.9276 1
Mycobacterium tuberculosis Possible hydrolase 0.0028 0.0182 0.0314
Loa Loa (eye worm) acetylcholinesterase 1 0.0079 0.0717 0.1292
Plasmodium vivax tubulin beta chain, putative 0.0471 0.482 0.4978
Echinococcus granulosus acetylcholinesterase 0.0079 0.0717 0.0717
Echinococcus granulosus raf serine:threonine protein kinase 0.005 0.0411 0.0411
Brugia malayi hypothetical protein 0.0025 0.0156 0.0162
Schistosoma mansoni nuclear receptor 0.0025 0.0156 0.0168
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0327 0.3311 0.5964
Mycobacterium ulcerans hydrolase 0.0028 0.0182 0.0603
Brugia malayi nuclear hormone receptor 0.0025 0.0156 0.0162
Onchocerca volvulus 0.0013 0.003 0.0039
Echinococcus granulosus intermediate filament protein 0.0031 0.022 0.022
Schistosoma mansoni sodium-dependent amino acid transporter 0.0048 0.0392 0.0422
Loa Loa (eye worm) hypothetical protein 0.0053 0.0452 0.0814
Echinococcus granulosus tubulin alpha 3 chain 0.0356 0.3619 0.3619
Giardia lamblia Hypothetical protein 0.0018 0.008 0.0098
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0188 0.0202
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0156 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.1403 0.2896
Brugia malayi bZIP transcription factor family protein 0.0018 0.008 0.0083
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Schistosoma mansoni tubulin subunit alpha 0.0356 0.3619 0.3902
Brugia malayi latrophilin 2 splice variant baaae 0.018 0.1779 0.1853
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.0984 0.0984
Loa Loa (eye worm) hypothetical protein 0.0025 0.0156 0.0281
Giardia lamblia Sugar-proton symporter 0.0015 0.0046 0.0055
Onchocerca volvulus 0.0028 0.0188 0.0338
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0286 0.035
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0041 0.0323 0.0385
Loa Loa (eye worm) hypothetical protein 0.0013 0.0032 0.0057
Echinococcus granulosus GPCR family 2 0.0083 0.0766 0.0766
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0019 0.0091 0.0094
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Trichomonas vaginalis mismatch repair protein Mlh2 (mutL homolog) 0.002 0.0103 0.0194
Entamoeba histolytica peptidase, C54 family 0.0027 0.0172 0.0199
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Trichomonas vaginalis tubulin alpha chain, putative 0.0471 0.482 1
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0019 0.0091 0.0163
Echinococcus granulosus beta tubulin 0.0471 0.482 0.482
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0511 0.055
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0056 0.0474 0.0474
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0053 0.0452 0.0452
Schistosoma mansoni hypothetical protein 0.002 0.0103 0.011
Schistosoma mansoni cpg binding protein 0.0032 0.0224 0.0241
Brugia malayi Hsp90 protein 0.0173 0.1707 0.1777
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0019 0.0091 0.0097
Loa Loa (eye worm) hypothetical protein 0.0053 0.0452 0.0814
Loa Loa (eye worm) hypothetical protein 0.0025 0.0156 0.0281
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0053 0.0452 0.0452
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0022 0.0119 0.0128
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Loa Loa (eye worm) tubulin alpha chain 0.0356 0.3619 0.652
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0041 0.0323 0.1168
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0156 0.0278
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0056 0.0474 0.0474
Brugia malayi steroid hormone receptor 0.0053 0.0452 0.047
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0452 0.0452
Plasmodium vivax geranylgeranyltransferase, putative 0.002 0.0102 0.0059
Entamoeba histolytica peptidase, C54 family 0.0027 0.0172 0.0199
Plasmodium vivax tubulin gamma chain, putative 0.0255 0.2562 0.2624
Plasmodium vivax importin-beta 2, putative 0.0032 0.0227 0.019
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0091 0.0091
Echinococcus multilocularis epidermal growth factor receptor 0.035 0.3549 0.3549
Trypanosoma cruzi beta tubulin, putative 0.0471 0.482 0.6356
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0024 0.0024
Giardia lamblia Beta tubulin 0.0471 0.482 0.5902
Onchocerca volvulus 0.0015 0.0046 0.0068
Entamoeba histolytica hypothetical protein 0.0026 0.0164 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0048 0.0392 0.0392
Schistosoma mansoni neuropeptide receptor 0.0059 0.0511 0.055
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Onchocerca volvulus 0.0013 0.0032 0.0042
Trichomonas vaginalis sensor histidine kinase, putative 0.0041 0.0323 0.0651
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0046 0.0075
Trichomonas vaginalis tubulin alpha chain, putative 0.0144 0.1403 0.2896
Plasmodium falciparum amino acid transporter, putative 0.0048 0.0392 0.0406
Loa Loa (eye worm) hypothetical protein 0.0013 0.0032 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0511 0.055
Leishmania major beta tubulin 0.0471 0.482 0.6538
Schistosoma mansoni tyrosine kinase 0.0022 0.0119 0.0128
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0024 0.0024
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0041 0.0323 0.0608
Brugia malayi Furin-like cysteine rich region family protein 0.035 0.3549 0.3696
Plasmodium falciparum DNA gyrase subunit B 0.0041 0.0323 0.0334
Loa Loa (eye worm) tubulin beta chain 0.0471 0.482 0.8684
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0041 0.0323 0.0323
Brugia malayi translation initiation factor 4E 0.0036 0.027 0.028
Brugia malayi follicle stimulating hormone receptor 0.0327 0.3311 0.3448
Loa Loa (eye worm) heat shock protein 90 0.0273 0.2744 0.4943
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0382 0.0412
Wolbachia endosymbiont of Brugia malayi DNA mismatch repair protein 0.002 0.0103 0.0231
Chlamydia trachomatis DNA gyrase subunit B 0.0041 0.0323 0.7611
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0041 0.0323 0.0385
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Echinococcus multilocularis Tubulin beta 2C chain 0.0471 0.482 0.482
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.0341 0.0341
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0036 0.027 0.0541
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0059 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0281 0.2836 0.5108
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0212 0.2109 0.4363
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0027 0.0172 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0452 0.047
Loa Loa (eye worm) hypothetical protein 0.0509 0.5213 0.939
Loa Loa (eye worm) alpha-tubulin 0.0356 0.3619 0.652
Echinococcus multilocularis tyrosine protein kinase Srms 0.0047 0.0385 0.0385
Loa Loa (eye worm) hypothetical protein 0.0053 0.0452 0.0814
Leishmania major epsilon tubulin, putative 0.0255 0.2562 0.3454
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0041 0.0323 0.0334
Trichomonas vaginalis tubulin epsilon chain, putative 0.0111 0.1051 0.2166
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0041 0.0323 0.0594
Brugia malayi hypothetical protein 0.0028 0.0188 0.0195
Trypanosoma cruzi heat shock protein 85, putative 0.0273 0.2744 0.36
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0041 0.0323 0.1118
Schistosoma mansoni autophagin-1 (C54 family) 0.0069 0.061 0.0657
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0393 0.0393
Mycobacterium tuberculosis Conserved protein 0.0041 0.0323 0.0608
Echinococcus granulosus neuropeptide FF receptor 2 0.0059 0.0511 0.0511
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0139 0.0141
Entamoeba histolytica ubiquitin like protein 0.0032 0.0228 0.0268
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0019 0.0091 0.0091
Trypanosoma brucei glucose transporter, putative 0.0032 0.0231 0.0263
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus multilocularis tubulin alpha 1C chain 0.0356 0.3619 0.3619
Loa Loa (eye worm) heat shock protein 75 0.0173 0.1707 0.3075
Schistosoma mansoni tar DNA-binding protein 0.0262 0.2629 0.2834
Loa Loa (eye worm) tubulin alpha-2 chain 0.0356 0.3619 0.652
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0041 0.0323 0.0651
Loa Loa (eye worm) hypothetical protein 0.0041 0.0323 0.0581
Brugia malayi protein-tyrosine kinase 0.0047 0.0385 0.04
Echinococcus granulosus Small ubiquitin modifier 2 0.0032 0.0228 0.0228
Toxoplasma gondii hypothetical protein 0.0048 0.0392 0.0406
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Mycobacterium ulcerans arylsulfatase AtsD 0.0028 0.0182 0.0603
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0036 0.0268 0.0268
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0382 0.0412
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0041 0.0323 0.0385
Giardia lamblia Grp94/Hsp90 0.0252 0.2524 0.309
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.0984 0.0984
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0091 0.0091
Plasmodium falciparum DNA mismatch repair protein PMS1, putative 0.002 0.0103 0.0106
Trypanosoma brucei glucose transporter, putative 0.0032 0.0231 0.0263
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.003 0.0054
Onchocerca volvulus 0.005 0.042 0.0778
Toxoplasma gondii small ubiquitin family modifier, putative 0.0032 0.0228 0.0236
Echinococcus granulosus tyrosine protein kinase Lyn 0.0056 0.0474 0.0474
Echinococcus granulosus Tubulin alpha 1 chain 0.0356 0.3619 0.3619
Loa Loa (eye worm) hypothetical protein 0.0028 0.0188 0.0338
Brugia malayi hypothetical protein 0.0011 0.001 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0102 0.0093
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0452 0.0452
Plasmodium vivax DNA mismatch repair protein MLH, putative 0.002 0.0103 0.006
Onchocerca volvulus 0.0015 0.0048 0.0073
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0069 0.061 0.1248
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.002 0.0102 0.0184
Onchocerca volvulus 0.0013 0.0032 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0059 0.0511 0.055
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0188 0.0195
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0392 0.0422
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0019 0.0091 0.0163
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0083 0.0766 0.0766
Brugia malayi Cell death specification protein 2 0.0018 0.008 0.0083
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0001 0.0001
Echinococcus granulosus acetylcholinesterase 0.0079 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Brugia malayi Protein kinase domain containing protein 0.0019 0.0094 0.0098
Echinococcus granulosus solute carrier family 22 0.0015 0.0046 0.0046
Trypanosoma cruzi zeta tubulin, putative 0.0111 0.1051 0.1353
Chlamydia trachomatis DNA gyrase subunit B 0.0041 0.0323 0.7611
Echinococcus granulosus g protein coupled receptor 0.0059 0.0511 0.0511
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0091 0.0094
Mycobacterium ulcerans putative regultory protein 0.0041 0.0323 0.1168
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0041 0.0323 0.0334
Giardia lamblia Delta tubulin 0.0111 0.1051 0.1287
Loa Loa (eye worm) hypothetical protein 0.0201 0.1993 0.359
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0036 0.027 0.0315
Loa Loa (eye worm) hypothetical protein 0.0018 0.008 0.0145
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Schistosoma mansoni endoplasmin 0.0273 0.2744 0.2958
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0164 0.0321
Trypanosoma cruzi epsilon tubulin, putative 0.0255 0.2562 0.3358
Loa Loa (eye worm) carboxylesterase 0.0013 0.0032 0.0057
Trypanosoma brucei heat shock protein, putative 0.0273 0.2744 0.36
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0393 0.0393
Onchocerca volvulus 0.0053 0.0452 0.0838
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.0341 0.0341
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0156 0.0156
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0018 0.008 0.008
Loa Loa (eye worm) steroid hormone receptor 0.0053 0.0452 0.0814
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0091 0.0094
Onchocerca volvulus Neuropeptide F receptor homolog 0.0059 0.0511 0.095
Onchocerca volvulus 0.003 0.0207 0.0373
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0059 0.0511 0.0511
Leishmania major mismatch repair protein, putative 0.002 0.0103 0.0096
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0286 0.0308
Brugia malayi Tubulin alpha-2 chain 0.0356 0.3619 0.3769
Trichomonas vaginalis spcc417.12 protein, putative 0.0013 0.0032 0.0046
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0156 0.0168
Leishmania major alpha tubulin 0.0356 0.3619 0.4898
Trichomonas vaginalis tubulin, putative 0.0111 0.1051 0.2166
Echinococcus multilocularis lamin dm0 0.0031 0.022 0.022
Loa Loa (eye worm) TYRA-2 protein 0.0059 0.0511 0.092
Loa Loa (eye worm) hypothetical protein 0.0028 0.0185 0.0334
Brugia malayi Phospholipase A2 family protein 0.0107 0.1012 0.1054
Brugia malayi Steroid receptor seven-up type 2 0.0053 0.0452 0.047
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0028 0.0188 0.0194
Echinococcus multilocularis tyrosine protein kinase shark 0.0013 0.003 0.003
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0104 0.0984 0.0984
Brugia malayi Pre-SET motif family protein 0.0193 0.1913 0.1992
Entamoeba histolytica hypothetical protein 0.0153 0.1491 0.1815
Echinococcus multilocularis Tubulin alpha 1 chain 0.0356 0.3619 0.3619
Trypanosoma brucei heat shock protein, putative 0.0273 0.2744 0.36
Echinococcus granulosus ccaat enhancer binding protein delta 0.0018 0.008 0.008
Echinococcus granulosus tyrosine kinase 0.0047 0.0385 0.0385
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0113 0.1078 0.1078
Loa Loa (eye worm) hypothetical protein 0.0028 0.0188 0.0338
Echinococcus granulosus tubulin alpha chain 0.0356 0.3619 0.3619
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0019 0.0091 0.0091
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0022 0.0023
Loa Loa (eye worm) hypothetical protein 0.0053 0.0452 0.0814
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0041 0.0323 0.0608
Echinococcus multilocularis cysteine protease atg4b 0.0069 0.061 0.061
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0139 0.0139
Echinococcus granulosus Tubulin alpha 1 chain 0.0356 0.3619 0.3619
Loa Loa (eye worm) tubulin alpha-3 chain 0.0212 0.2109 0.3799
Trichomonas vaginalis heat shock protein, putative 0.0252 0.2524 0.5227
Mycobacterium ulcerans arylsulfatase AtsD 0.0028 0.0182 0.0603
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0046 0.0056
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0053 0.0452 0.0814
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0027 0.0172 0.0178
Trichomonas vaginalis tubulin, putative 0.0144 0.1403 0.2896
Loa Loa (eye worm) hypothetical protein 0.0048 0.0392 0.0706
Schistosoma mansoni nck2/grb4 0.0017 0.0073 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0053 0.0452 0.047
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.022 0.0397
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Schistosoma mansoni nAChR subunit 0.0019 0.0091 0.0097
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0245 0.246 0.5094
Brugia malayi photoreceptor-specific nuclear receptor 0.0053 0.0452 0.047
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0498 0.0517
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0231 0.0263
Trypanosoma cruzi Heat shock protein 83, putative 0.0273 0.2744 0.36
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0076 0.0081
Leishmania major alpha tubulin 0.0356 0.3619 0.4898
Brugia malayi Tubulin alpha chain 0.0111 0.1051 0.1095
Trichomonas vaginalis tubulin beta chain, putative 0.0471 0.482 1
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0019 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0384 0.3911 0.7045
Schistosoma mansoni adapter molecule crk 0.0017 0.0073 0.0078
Brugia malayi Melatonin receptor type 1A 0.0059 0.0511 0.0531
Leishmania major beta tubulin 0.0471 0.482 0.6538
Plasmodium falciparum tubulin epsilon chain, putative 0.0255 0.2562 0.2658
Schistosoma mansoni hypothetical protein 0.0018 0.008 0.0086
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0231 0.0459
Brugia malayi intermediate filament protein 0.0031 0.022 0.0229
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0156 0.0156
Entamoeba histolytica DNA topoisomerase II, putative 0.0041 0.0323 0.0384
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0028 0.0182 0.0314
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0056 0.0474 0.0474
Plasmodium vivax DNA topoisomerase II, putative 0.0041 0.0323 0.0289
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0471 0.482 0.482
Toxoplasma gondii heat shock protein 75, putative 0.0173 0.1707 0.177
Schistosoma mansoni par domain protein 0.0018 0.008 0.0086
Schistosoma mansoni steroid hormone receptor ad4bp 0.0053 0.0452 0.0486
Loa Loa (eye worm) cell death specification protein 2 0.0018 0.008 0.0145
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.003 0.0054
Echinococcus multilocularis neuropeptide receptor A26 0.0966 1 1
Schistosoma mansoni nAChR subunit 0.0019 0.0091 0.0097
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0452 0.047
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0056 0.0474 0.0474
Onchocerca volvulus 0.0059 0.0511 0.095
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0077 0.0059
Echinococcus granulosus solute carrier family 22 0.0015 0.0046 0.0046
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0015 0.0046 0.0029
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0059 0.0511 0.0511
Trypanosoma cruzi heat shock protein 90, putative 0.0119 0.114 0.147
Schistosoma mansoni RAR-like nuclear receptor 0.0053 0.0452 0.0486
Onchocerca volvulus 0.0015 0.0046 0.0068
Echinococcus multilocularis tubulin alpha 3 chain 0.0356 0.3619 0.3619
Mycobacterium tuberculosis Possible two component sensor kinase 0.0041 0.0323 0.0608
Plasmodium vivax tubulin alpha chain, putative 0.0356 0.3619 0.3726
Schistosoma mansoni nAChR subunit 0.0019 0.0091 0.0097
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0286 0.0337
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Schistosoma mansoni opsin-like receptor 0.0059 0.0511 0.055
Brugia malayi DNA mismatch repair protein MutL containing protein 0.002 0.0103 0.0106
Onchocerca volvulus Protein ultraspiracle homolog 0.0053 0.0452 0.0838
Brugia malayi Protein kinase domain containing protein 0.0013 0.003 0.0031
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0056 0.0474 0.0474
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0102 0.0193
Echinococcus granulosus neuropeptide receptor 0.0059 0.0511 0.0511
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0041 0.0323 0.0323
Schistosoma mansoni histamine h1 receptor 0.0059 0.0511 0.055
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0111 0.1051 0.109
Echinococcus multilocularis BC026374 protein (S09 family) 0.0013 0.0032 0.0032
Onchocerca volvulus 0.0015 0.0046 0.0068
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0511 0.055
Onchocerca volvulus Putative nachr subunit 0.0019 0.0091 0.0154
Echinococcus granulosus MAM 0.0015 0.0048 0.0048
Schistosoma mansoni hypothetical protein 0.0059 0.0511 0.055
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus granulosus tubulin alpha chain 0.0356 0.3619 0.3619
Schistosoma mansoni nAChR subunit 0.0019 0.0091 0.0097
Mycobacterium tuberculosis Probable two component sensor kinase 0.0041 0.0323 0.0608
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0091
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0046 0.0075
Echinococcus granulosus G protein coupled receptor 139 0.0059 0.0511 0.0511
Loa Loa (eye worm) sugar transporter 0.0104 0.0984 0.1772
Brugia malayi nuclear receptor NHR-67 0.0025 0.0156 0.0162
Schistosoma mansoni hypothetical protein 0.0083 0.0766 0.0825
Echinococcus granulosus alpha tubulin 0.0356 0.3619 0.3619
Echinococcus granulosus NCK adaptor protein 0.0017 0.0073 0.0073
Echinococcus granulosus somatostatin receptor 0.0059 0.0511 0.0511
Trypanosoma brucei alpha tubulin 0.0356 0.3619 0.4761
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0069 0.061 0.1248
Echinococcus granulosus General substrate transporter 0.009 0.083 0.083
Leishmania major beta tubulin 0.0471 0.482 0.6538
Leishmania major GTP-binding protein, putative 0.0024 0.0139 0.0145
Loa Loa (eye worm) BEN-1 protein 0.0471 0.482 0.8684
Echinococcus multilocularis tubulin epsilon chain 0.0255 0.2562 0.2562
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.0984 0.0984
Onchocerca volvulus 0.0059 0.0511 0.095
Echinococcus multilocularis tubulin alpha 1C chain 0.0356 0.3619 0.3619
Onchocerca volvulus 0.0059 0.0511 0.095
Brugia malayi Tubulin beta chain 0.0111 0.1051 0.1095
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0046 0.0017
Schistosoma mansoni ran 0.0024 0.0139 0.0149
Echinococcus multilocularis neuropeptide FF receptor 2 0.0059 0.0511 0.0511
Echinococcus granulosus insulin receptor 0.0113 0.1078 0.1078
Schistosoma mansoni glucose transport protein 0.0104 0.0984 0.106
Echinococcus multilocularis ecdysone induced protein 78C 0.0053 0.0452 0.0452
Echinococcus multilocularis solute carrier family 22 0.0015 0.0046 0.0046
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.2481 0.2481
Loa Loa (eye worm) sugar transporter 0.0015 0.0046 0.0082
Brugia malayi Importin beta-1 subunit 0.0032 0.0227 0.0236
Trypanosoma cruzi mismatch repair protein PMS1, putative 0.002 0.0103 0.0093
Echinococcus multilocularis g-protein coupled receptor 0.0059 0.0511 0.0511
Echinococcus granulosus biogenic amine 5HT receptor 0.0201 0.1993 0.1993
Echinococcus multilocularis tubulin subunit beta 0.0471 0.482 0.482
Brugia malayi hypothetical protein 0.0059 0.0511 0.0531
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0091 0.0091
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0252 0.2524 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0059 0.0511 0.055
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.002 0.0102 0.0102
Brugia malayi hypothetical protein 0.0059 0.0511 0.0531
Brugia malayi Tubulin gamma chain 0.0255 0.2562 0.2668
Echinococcus multilocularis solute carrier family 22 0.0015 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0053 0.0452 0.0814
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus multilocularis General substrate transporter 0.009 0.083 0.083
Schistosoma mansoni hypothetical protein 0.0104 0.0984 0.106
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0091 0.0097
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0046 0.0017
Trichomonas vaginalis tubulin beta chain, putative 0.0356 0.3619 0.7504
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Trypanosoma cruzi heat shock protein 90, putative 0.0231 0.2313 0.3028
Echinococcus multilocularis thyroid hormone receptor alpha 0.0053 0.0452 0.0452
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus granulosus transcriptional factor nfil3:e4bp4 0.0018 0.008 0.008
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0053 0.0452 0.0452
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Echinococcus granulosus sodium and chloride dependent glycine 0.0048 0.0392 0.0392
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0028 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0511 0.0511
Echinococcus granulosus bloom syndrome protein 0.0025 0.0155 0.0155
Plasmodium vivax hexose transporter 0.0104 0.0984 0.0978
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0069 0.061 0.1248
Schistosoma mansoni myosin xvIII 0.0059 0.0511 0.055
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0139 0.0144
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0091 0.0097
Brugia malayi RE15519p 0.0059 0.0511 0.0531
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0156 0.0168
Loa Loa (eye worm) hypothetical protein 0.0013 0.0032 0.0057
Echinococcus multilocularis tubulin alpha chain 0.0356 0.3619 0.3619
Echinococcus granulosus g protein coupled receptor 0.0059 0.0511 0.0511
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0059 0.0511 0.055
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0001 0.0001
Brugia malayi Carboxylesterase family protein 0.0013 0.0032 0.0032
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0041 0.0323 0.0385
Loa Loa (eye worm) hypothetical protein 0.0028 0.0188 0.0338
Trypanosoma cruzi lanosterol synthase, putative 0.0733 0.7566 1
Brugia malayi G-protein coupled receptor 0.0059 0.0511 0.0531
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Brugia malayi hypothetical protein 0.0247 0.2481 0.2584
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0046 0.0056
Giardia lamblia Sentrin 0.0032 0.0228 0.0278
Trypanosoma brucei heat shock protein 90, putative 0.0273 0.2744 0.36
Schistosoma mansoni hypothetical protein 0.0897 0.9276 1
Entamoeba histolytica hypothetical protein 0.0153 0.1491 0.1815
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Echinococcus granulosus tachykinin peptides receptor 99D 0.0059 0.0511 0.0511
Loa Loa (eye worm) raf kinase 0.0045 0.0364 0.0656
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0051 0.0051
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0059 0.0511 0.055
Echinococcus granulosus Tubulin alpha 1 chain 0.0356 0.3619 0.3619
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0252 0.2524 1
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0053 0.0452 0.0838
Echinococcus granulosus neuropeptide Y receptor 0.0059 0.0511 0.0511
Brugia malayi ecdysteroid receptor 0.0053 0.0452 0.047
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0017
Schistosoma mansoni neuropeptide receptor 0.0059 0.0511 0.055
Echinococcus granulosus Tubulin beta 2C chain 0.0471 0.482 0.482
Schistosoma mansoni tar DNA-binding protein 0.0262 0.2629 0.2834
Entamoeba histolytica hypothetical protein 0.0225 0.2247 0.2742
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0156 0.0156
Brugia malayi neuropeptide F receptor 0.0059 0.0511 0.0531
Trichomonas vaginalis tubulin, putative 0.0144 0.1403 0.2896
Echinococcus granulosus g-protein coupled receptor 0.0059 0.0511 0.0511
Onchocerca volvulus 0.0515 0.5284 1
Brugia malayi hypothetical protein 0.0059 0.0511 0.0531
Trypanosoma cruzi zeta tubulin, putative 0.0111 0.1051 0.1353
Schistosoma mansoni nAChR subunit 0.0019 0.0091 0.0097
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Brugia malayi hypothetical protein 0.0015 0.0046 0.0047
Schistosoma mansoni biogenic amine (5HT) receptor 0.0059 0.0511 0.055
Brugia malayi DNA mismatch repair protein MutL containing protein 0.002 0.0103 0.0106
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.002 0.0102 0.011
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0286 0.0286
Leishmania major glucose transporter, lmgt3 0.0032 0.0231 0.0271
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Plasmodium vivax small ubiquitin-related modifier, putative 0.0032 0.0228 0.019
Schistosoma mansoni tubulin subunit beta 0.0471 0.482 0.5196
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0032 0.0033
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0019 0.0091 0.0094
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0019 0.0091 0.0091
Schistosoma mansoni hypothetical protein 0.0083 0.0766 0.0825
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0411 0.0442
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0046 0.0017
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0262 0.2629 0.4736
Loa Loa (eye worm) carboxylesterase 0.0079 0.0717 0.1292
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0041 0.0323 0.1168
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Plasmodium falciparum endoplasmin, putative 0.0194 0.1927 0.1999
Trichomonas vaginalis tubulin beta chain, putative 0.0356 0.3619 0.7504
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0193 0.1913 0.3447
Brugia malayi Muscle positioning protein 4 0.0014 0.0037 0.0038
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Toxoplasma gondii DNA topoisomerase 2, putative 0.0041 0.0323 0.0334
Echinococcus granulosus FTZ F1 alpha 0.0053 0.0452 0.0452
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0019 0.0091 0.0163
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0156 0.0156
Echinococcus multilocularis tyrosine protein kinase HCK 0.0038 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Brugia malayi Cation transporter family protein 0.0019 0.0091 0.0094
Schistosoma mansoni sodium/chloride dependent transporter 0.0048 0.0392 0.0422
Onchocerca volvulus 0.0013 0.003 0.0039
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0046 0.0056
Entamoeba histolytica tubulin alpha-1 chain 0.0356 0.3619 0.4425
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.1051 0.2166
Schistosoma mansoni hypothetical protein 0.006 0.0522 0.0562
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0392 0.0422
Schistosoma mansoni heat shock protein 0.0273 0.2744 0.2958
Leishmania major heat shock protein 83-1 0.0273 0.2744 0.3703
Schistosoma mansoni transcriptional factor nfil3/e4bp4 0.0018 0.008 0.0086
Schistosoma mansoni glucose transport protein 0.0104 0.0984 0.106
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0046 0.0017
Brugia malayi Raf kinase 0.005 0.0411 0.0427
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0091 0.0097
Brugia malayi nuclear hormone receptor 0.0053 0.0452 0.047
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0188 0.0202
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Onchocerca volvulus 0.0018 0.008 0.0134
Trypanosoma brucei beta tubulin 0.0471 0.482 0.6356
Echinococcus multilocularis neuropeptide Y receptor 0.0059 0.0511 0.0511
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0046 0.0075
Loa Loa (eye worm) TK/FER protein kinase 0.0013 0.003 0.0054
Onchocerca volvulus 0.0015 0.0046 0.0068
Echinococcus multilocularis carboxylesterase 5A 0.0079 0.0717 0.0717
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0164 0.0175
Giardia lamblia Hypothetical protein 0.0028 0.0182 0.0222
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0013 0.0032 0.0032
Brugia malayi G-protein coupled receptor 0.0059 0.0511 0.0531
Echinococcus granulosus lamin dm0 0.0031 0.022 0.022
Echinococcus granulosus tubulin alpha chain 0.0356 0.3619 0.3619
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0163
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0046 0.0046
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0156 0.0162
Onchocerca volvulus Huntingtin homolog 0.0384 0.3911 0.7396
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0156 0.0278
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0984 0.2025
Echinococcus multilocularis sodium and chloride dependent glycine 0.0048 0.0392 0.0392
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Echinococcus granulosus tyrosine kinase 0.0013 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0013 0.0032 0.0032
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0231 0.0263
Schistosoma mansoni tar DNA-binding protein 0.0262 0.2629 0.2834
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0173 0.1707 0.3218
Schistosoma mansoni DNA mismatch repair protein MLH1 0.002 0.0103 0.011
Onchocerca volvulus 0.0015 0.0048 0.0073
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.002 0.0102 0.0193
Trypanosoma cruzi heat shock protein 90, putative 0.0273 0.2744 0.36
Schistosoma mansoni microrchidia 2a 0.002 0.0103 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Brugia malayi hypothetical protein 0.0018 0.008 0.0083
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0188 0.0188
Schistosoma mansoni endoplasmin 0.0273 0.2744 0.2958
Brugia malayi Tubulin alpha-2 chain 0.0356 0.3619 0.3769
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus granulosus neuropeptide receptor A26 0.0966 1 1
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0048 0.0392 0.0392
Plasmodium falciparum protein farnesyltransferase subunit beta 0.002 0.0102 0.0106
Loa Loa (eye worm) serotonin transporter b 0.0281 0.2836 0.5108
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0046 0.0046
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0392 0.0407
Trypanosoma cruzi hexose transporter 0.0032 0.0231 0.0263
Echinococcus granulosus tyrosine protein kinase Srms 0.0013 0.003 0.003
Treponema pallidum heat shock protein 90 0.0252 0.2524 0.886
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0059 0.0511 0.055
Loa Loa (eye worm) hypothetical protein 0.0028 0.0188 0.0338
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Echinococcus granulosus fmrfamide receptor 0.0059 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Leishmania major myo-inositol/proton symporter (MIT) 0.0015 0.0046 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0053 0.0452 0.0814
Schistosoma mansoni hypothetical protein 0.005 0.042 0.0452
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0036 0.027 0.029
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0156 0.0156
Brugia malayi nuclear receptor RXR 0.0028 0.0188 0.0195
Loa Loa (eye worm) hypothetical protein 0.0515 0.5284 0.9519
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0076 0.0076
Loa Loa (eye worm) SRC-1 0.0056 0.0474 0.0855
Loa Loa (eye worm) hypothetical protein 0.0048 0.0392 0.0706
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.002 0.0102 0.011
Echinococcus multilocularis serotonin transporter 0.0281 0.2836 0.2836
Loa Loa (eye worm) hypothetical protein 0.0048 0.0392 0.0706
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0231 0.0263
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0156 0.0162
Loa Loa (eye worm) hypothetical protein 0.0017 0.0073 0.0132
Plasmodium vivax tubulin alpha chain, putative 0.0356 0.3619 0.3726
Echinococcus granulosus tm gpcr rhodopsin 0.0059 0.0511 0.0511
Trypanosoma brucei glucose transporter, putative 0.0032 0.0231 0.0263
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Schistosoma mansoni biogenic amine receptor 0.0059 0.0511 0.055
Echinococcus multilocularis GPCR, family 2 0.0083 0.0766 0.0766
Onchocerca volvulus 0.0015 0.0046 0.0068
Trypanosoma brucei heat shock protein 90, putative 0.0273 0.2744 0.36
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0053 0.0452 0.0452
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0358
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0041 0.0323 0.0651
Schistosoma mansoni hypothetical protein 0.0013 0.0024 0.0025
Schistosoma mansoni tubulin subunit beta 0.0471 0.482 0.5196
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0046 0.0075
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0286 0.0575
Onchocerca volvulus 0.0018 0.008 0.0134
Leishmania major beta tubulin 0.0471 0.482 0.6538
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Echinococcus multilocularis beta tubulin 0.0471 0.482 0.482
Echinococcus granulosus Tubulin beta 2C chain 0.0471 0.482 0.482
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0392 0.0361
Brugia malayi neuropeptide F receptor 0.0059 0.0511 0.0531
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0173 0.1707 0.208
Echinococcus granulosus tyrosine protein kinase Src42A 0.0056 0.0474 0.0474
Brugia malayi CXXC zinc finger family protein 0.003 0.0207 0.0215
Echinococcus multilocularis tyrosine protein kinase Blk 0.0047 0.0385 0.0385
Trichomonas vaginalis heat shock protein, putative 0.0273 0.2744 0.5684
Echinococcus multilocularis sex peptide receptor 0.0059 0.0511 0.0511
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0059 0.0511 0.0531
Trypanosoma brucei heat shock protein, putative 0.0273 0.2744 0.36
Giardia lamblia Heat shock protein HSP 90-alpha 0.0231 0.2313 0.2832
Loa Loa (eye worm) MH2 domain-containing protein 0.0258 0.2588 0.4661
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0046 0.0047
Schistosoma mansoni tubulin subunit beta 0.0471 0.482 0.5196
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0051 0.0051
Plasmodium falciparum cysteine protease ATG4, putative 0.0027 0.0172 0.0178
Loa Loa (eye worm) tubulin alpha 2 0.0245 0.246 0.4432
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0022 0.0023
Echinococcus granulosus BC026374 protein S09 family 0.0013 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Trypanosoma brucei heat shock protein, putative 0.0273 0.2744 0.36
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0041 0.0323 0.0608
Brugia malayi Sugar transporter family protein 0.0015 0.0046 0.0047
Leishmania major alpha tubulin 0.0356 0.3619 0.4898
Brugia malayi GoLoco motif family protein 0.0013 0.0024 0.0025
Leishmania major alpha tubulin 0.0356 0.3619 0.4898
Loa Loa (eye worm) hypothetical protein 0.0059 0.0511 0.092
Loa Loa (eye worm) norepinephrine transporter 0.0281 0.2836 0.5108
Trichomonas vaginalis tubulin alpha chain, putative 0.0144 0.1403 0.2896
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0076 0.0136
Schistosoma mansoni smad 0.0018 0.0076 0.0081
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0791 0.8167 1
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0471 0.4823 1
Schistosoma mansoni glucose transport protein 0.0104 0.0984 0.106
Trypanosoma brucei DNA topoisomerase ii 0.0041 0.0323 0.0385
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0053 0.0452 0.047
Onchocerca volvulus 0.0015 0.0046 0.0068
Echinococcus multilocularis tubulin beta 1 chain 0.0471 0.482 0.482
Echinococcus granulosus smad 0.0018 0.0076 0.0076
Echinococcus granulosus tubulin alpha chain 0.0356 0.3619 0.3619
Loa Loa (eye worm) tubulin beta-4 chain 0.0471 0.482 0.8684
Onchocerca volvulus 0.0281 0.2836 0.5358
Trichomonas vaginalis ran, putative 0.0024 0.0139 0.0269
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0385 0.0385
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0082

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 31 nM Inhibitory activity against alpha-2A adrenergic receptor by using [3H]-MK912 as radioligand expressed in COS-1 cells ChEMBL. 16002290
IC50 (binding) = 31 nM Inhibitory activity against alpha-2A adrenergic receptor by using [3H]-MK912 as radioligand expressed in COS-1 cells ChEMBL. 16002290
IC50 (binding) = 560 nM Inhibitory activity against neuropeptide Y receptor type 5 by using [125I]-PYY as radioligand expressed in COS-1 cells ChEMBL. 16002290
IC50 (binding) = 560 nM Inhibitory activity against neuropeptide Y receptor type 5 by using [125I]-PYY as radioligand expressed in COS-1 cells ChEMBL. 16002290
IC50 (binding) = 960 nM Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HEK293 cells ChEMBL. 16002290
IC50 (binding) = 960 nM Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HEK293 cells ChEMBL. 16002290

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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