Detailed information for compound 404636

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1034.23 | Formula: C49H71N13O10S
  • H donors: 12 H acceptors: 11 LogP: -1.28 Rotable bonds: 35
    Rule of 5 violations (Lipinski): 4
  • SMILES: CNCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(SC)(C)C)C(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)O)Cc1ccccc1)Cc1nc[nH]c1)Cc1ccc(cc1)O)C(C)C)CCCN=C(N)N
  • InChi: 1S/C49H71N13O10S/c1-28(2)39(60-41(65)33(56-38(64)26-52-5)14-10-20-54-48(50)51)44(68)57-34(22-30-16-18-32(63)19-17-30)42(66)61-40(49(3,4)73-6)45(69)58-35(24-31-25-53-27-55-31)46(70)62-21-11-15-37(62)43(67)59-36(47(71)72)23-29-12-8-7-9-13-29/h7-9,12-13,16-19,25,27-28,33-37,39-40,52,63H,10-11,14-15,20-24,26H2,1-6H3,(H,53,55)(H,56,64)(H,57,68)(H,58,69)(H,59,67)(H,60,65)(H,61,66)(H,71,72)(H4,50,51,54)
  • InChiKey: UCJANQXUYWVSGJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0015 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0014 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0156 0.0319 0.0319
Onchocerca volvulus 0.0298 0.0628 1
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0011 0.0004 0.0004
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0045 0.008 0.008
Mycobacterium ulcerans transcriptional regulatory protein 0.0018 0.0021 0.1376
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0199 0.0199
Schistosoma mansoni biogenic amine receptor 0.0018 0.0019 0.0019
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0875 0.1876 0.1876
Trichomonas vaginalis esterase, putative 0.0023 0.003 0.003
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0036 0.0036
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0056 0.0103 0.0102
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0067 0.0066
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.003 0.003
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0298 0.0628 0.0628
Schistosoma mansoni acetylcholine receptor subunit beta 0.0015 0.0014 0.0014
Leishmania major hypothetical protein, unknown function 0.0018 0.0021 0.002
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0298 0.0628 0.0628
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0018 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Echinococcus granulosus inositol monophosphatase 1 0.0023 0.0032 0.0032
Onchocerca volvulus 0.0257 0.0539 0.8586
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0045 0.008 0.1255
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0026 0.0038 0.0038
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0011 0.0004 0.0004
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0033 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0019 0.0019
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0009 0.0002 0.0024
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0019 0.0019
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0018 0.0021 0.0021
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0045 0.008 0.008
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0298 0.0628 1
Schistosoma mansoni nAChR subunit 0.0015 0.0014 0.0014
Echinococcus granulosus single minded 2 0.0011 0.0004 0.0004
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.002 0.0025 0.0025
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.3441 0.7433 0.7433
Schistosoma mansoni hypothetical protein 0.0499 0.1061 0.1061
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0021 0.0021
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0009 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0019 0.0019
Mycobacterium ulcerans transmembrane transport protein 0.0018 0.0021 0.1376
Brugia malayi putative neuropeptide receptor NPR1 0.0018 0.0019 0.0019
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0025 0.0036 0.0036
Loa Loa (eye worm) beta-lactamase 0.0023 0.003 0.003
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0018 0.002 0.002
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0056 0.0103 0.0103
Schistosoma mansoni cpg binding protein 0.0019 0.0022 0.0022
Loa Loa (eye worm) phosphatidylinositol 3 0.0298 0.0628 0.0628
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0077 0.0148 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0875 0.1876 0.1876
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0446 0.0946 0.0946
Brugia malayi RNA recognition motif domain containing protein 0.0037 0.0061 0.0061
Mycobacterium leprae conserved hypothetical protein 0.0023 0.003 0.0416
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0156 0.0319 0.5084
Schistosoma mansoni synaptojanin 0.0009 0.0001 0.0001
Brugia malayi mothers against decapentaplegic homolog 3 0.0009 0.0002 0.0002
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0056 0.0103 0.0103
Trichomonas vaginalis ap endonuclease, putative 0.0045 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.002 0.0024 0.0024
Echinococcus multilocularis neuropeptide FF receptor 2 0.0018 0.0019 0.0019
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0298 0.0628 1
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0018 0.0021 0.0021
Mycobacterium tuberculosis Conserved protein 0.0023 0.003 0.0464
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0033 0.0053 0.0053
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0018 0.0019 0.0019
Schistosoma mansoni lozenge 0.0032 0.0051 0.0051
Entamoeba histolytica hypothetical protein 0.0298 0.0628 0.0628
Trichomonas vaginalis PIKK family atypical protein kinase 0.2737 0.5908 0.5908
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0067 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.1551 0.3341 0.3341
Schistosoma mansoni hypothetical protein 0.0032 0.005 0.005
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0033 0.0053 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0067 0.0066
Echinococcus multilocularis dna polymerase eta 0.0059 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Mycobacterium tuberculosis Conserved protein 0.0023 0.003 0.0464
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.02 0.0414 0.0414
Loa Loa (eye worm) solute carrier family 6 member 4 0.015 0.0306 0.0306
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0298 0.0628 0.0628
Leishmania major hypothetical protein, unknown function 0.0298 0.0628 0.0627
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0032 0.003
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0199 0.0199
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0019 0.0019
Schistosoma mansoni cpg binding protein 0.0018 0.002 0.002
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0298 0.0628 0.0628
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1551 0.3341 0.334
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0022
Echinococcus granulosus cGMP dependent protein kinase 0.0019 0.0022 0.0022
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Entamoeba histolytica protein kinase rad3, putative 0.0875 0.1876 0.1876
Schistosoma mansoni transcription factor LCR-F1 0.0028 0.0042 0.0042
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0045 0.008 0.008
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.4626 1 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.002 0.002
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0028 0.0042 0.0055
Schistosoma mansoni fkbp-rapamycin associated protein 0.0875 0.1876 0.1876
Brugia malayi hypothetical protein 0.002 0.0024 0.0024
Loa Loa (eye worm) intermediate filament protein 0.0016 0.0017 0.0017
Schistosoma mansoni nAChR subunit 0.0033 0.0053 0.0053
Brugia malayi beta-lactamase family protein 0.0023 0.003 0.003
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0025 0.0036 0.0581
Trichomonas vaginalis PIKK family atypical protein kinase 0.2764 0.5968 0.5968
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0032 0.005 0.005
Echinococcus granulosus lamin 0.0016 0.0017 0.0017
Brugia malayi G protein-coupled receptor 0.0018 0.0019 0.0019
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0019 0.0019
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.02 0.0414 0.0414
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0009 0.0001 0.0001
Plasmodium vivax ataxin-2 like protein, putative 0.002 0.0024 0.0362
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0018 0.0019 0.0019
Plasmodium falciparum flap endonuclease 1 0.002 0.0025 0.0384
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0875 0.1876 0.1876
Echinococcus granulosus mothers against decapentaplegic 6 0.0009 0.0002 0.0002
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0018 0.0019 0.0019
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0033 0.0053 0.0053
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0033 0.0053 0.0053
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0015 0.0014 0.0014
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0033 0.0053 0.0053
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Schistosoma mansoni intermediate filament proteins 0.0016 0.0017 0.0017
Echinococcus granulosus smad 0.0021 0.0026 0.0026
Schistosoma mansoni sodium/chloride dependent transporter 0.015 0.0306 0.0306
Echinococcus granulosus serotonin transporter 0.015 0.0306 0.0306
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0018 0.0021 0.002
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0298 0.0628 0.0628
Brugia malayi RE15519p 0.0018 0.0019 0.0019
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0008 0.0007
Brugia malayi follicle stimulating hormone receptor 0.0018 0.0019 0.0019
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0039 0.0065 0.0065
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0036 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.3441 0.7433 0.7433
Mycobacterium ulcerans esterase/lipase LipP 0.0023 0.003 0.2354
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0046 0.006
Echinococcus multilocularis hyperpolarization activated cyclic 0.0026 0.0038 0.0038
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0298 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0048 0.0086 0.0086
Echinococcus multilocularis hyperpolarization activated cyclic 0.0026 0.0038 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0018 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0009 0.0001 0.0001
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0067 0.0067
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0056 0.0103 0.3333
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0045 0.008 1
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.4626 1 1
Echinococcus multilocularis flap endonuclease 1 0.002 0.0025 0.0025
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0009 0.0001 0.0001
Brugia malayi hypothetical protein 0.0122 0.0245 0.0245
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0036 0.0036
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0023 0.003 0.003
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) ACC-1 protein 0.0033 0.0053 0.0053
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0015 0.0014 0.0014
Trichomonas vaginalis adenylate cyclase type, putative 0.0011 0.0004 0.0004
Schistosoma mansoni smad1 5 8 and 0.0021 0.0026 0.0026
Echinococcus multilocularis neutral sphingomyelinase 0.0009 0.0001 0.0001
Schistosoma mansoni nAChR subunit 0.0033 0.0053 0.0053
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0021 0.0026 0.04
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0008 0.0007
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0298 0.0628 0.0627
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0018 0.0021 0.0021
Loa Loa (eye worm) RNA binding protein 0.0037 0.0061 0.0061
Onchocerca volvulus 0.0018 0.0019 0.0308
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.003 0.003
Echinococcus granulosus 7tm_1 domain containing protein 0.0018 0.0019 0.0019
Echinococcus granulosus flap endonuclease 1 0.002 0.0025 0.0025
Onchocerca volvulus 0.0018 0.002 0.0319
Echinococcus granulosus mothers against decapentaplegic 2 0.0009 0.0002 0.0002
Echinococcus multilocularis neuropeptide s receptor 0.0018 0.0019 0.0019
Brugia malayi Cyclic-nucleotide gated cation channel 0.0026 0.0038 0.0038
Brugia malayi Ets-domain containing protein 0.0044 0.0077 0.0077
Loa Loa (eye worm) MH1 domain-containing protein 0.0009 0.0002 0.0002
Schistosoma mansoni opsin-like receptor 0.0018 0.0019 0.0019
Onchocerca volvulus 0.0018 0.0019 0.0308
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis CMGC family protein kinase 0.0028 0.0042 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.4626 1 1
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0018 0.0021 0.0027
Onchocerca volvulus 0.0018 0.0019 0.0308
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0298 0.0628 0.0627
Trypanosoma cruzi importin beta-1 subunit, putative 0.0015 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0576 0.123 0.123
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0009 0.0001 0.0001
Echinococcus granulosus hypothetical protein 0.0018 0.0019 0.0019
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0298 0.0628 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.02 0.0414 0.0414
Schistosoma mansoni Smad4 0.0009 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0067 0.0066
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0298 0.0628 1
Onchocerca volvulus 0.0018 0.0019 0.0308
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0298 0.0628 0.0628
Echinococcus multilocularis nAChR subunit 0.0018 0.002 0.002
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0033 0.0053 0.0053
Brugia malayi hypothetical protein 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0154 0.0316 0.0316
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0018 0.0019 0.0308
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0298 0.0628 0.0627
Trichomonas vaginalis PIKK family atypical protein kinase 0.368 0.795 0.795
Trichomonas vaginalis ran, putative 0.0014 0.0011 0.0011
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0067 0.0067
Brugia malayi hypothetical protein 0.0018 0.0019 0.0019
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0018 0.0021 0.0027
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0019 0.0019
Echinococcus granulosus glycine receptor subunit alpha 1 0.0033 0.0053 0.0053
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0033 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0019 0.0019
Schistosoma mansoni importin beta-1 0.0019 0.0022 0.0022
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0298 0.0628 0.0627
Trichomonas vaginalis PIKK family atypical protein kinase 0.1551 0.3341 0.3341
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0018 0.0021 0.0021
Schistosoma mansoni voltage-gated potassium channel 0.0129 0.0262 0.0262
Schistosoma mansoni histamine h1 receptor 0.0018 0.0019 0.0019
Echinococcus granulosus peptide allatostatin:somatostatin 0.0018 0.0019 0.0019
Brugia malayi hypothetical protein 0.0018 0.0019 0.0019
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.4626 1 1
Schistosoma mansoni hypothetical protein 0.0032 0.005 0.005
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0014 0.0011 0.001
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0009 0.0001 0.0001
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0298 0.0628 1
Schistosoma mansoni neuropeptide receptor 0.0018 0.0019 0.0019
Schistosoma mansoni acetylcholine receptor-related 0.0015 0.0014 0.0014
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0046 0.0046
Echinococcus granulosus mitogen activated protein kinase 0.0028 0.0042 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.368 0.795 0.795
Entamoeba histolytica hypothetical protein 0.0298 0.0628 0.0628
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0019 0.0019
Trypanosoma brucei protein kinase A regulatory subunit 0.0018 0.0021 0.002
Echinococcus multilocularis traf and tnf receptor associated protein 0.0009 0.0001 0.0001
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0018 0.0019 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Brugia malayi Dopamine receptor protein 2 0.0018 0.0019 0.0019
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.015 0.0306 0.0306
Echinococcus multilocularis mothers against decapentaplegic 6 0.0009 0.0002 0.0002
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0033 0.0053 0.0053
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0018 0.0021 0.002
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0061 0.0061
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Schistosoma mansoni survival motor neuron protein 0.0085 0.0166 0.0166
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0018 0.0021 0.002
Onchocerca volvulus 0.0018 0.0019 0.0308
Loa Loa (eye worm) LGC-31 protein 0.0033 0.0053 0.0053
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0009 0.0001 0.0001
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.4626 1 1
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0036 0.0036
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0012 0.0007 0.0007
Schistosoma mansoni neutral sphingomyelinase 0.0009 0.0001 0.0001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0015 0.0014 0.0014
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0019 0.0019
Echinococcus granulosus tar DNA binding protein 0.0037 0.0061 0.0061
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0033 0.0053 0.0053
Mycobacterium tuberculosis Probable lipase LipE 0.0023 0.003 0.0464
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.4626 1 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0298 0.0628 0.0628
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0085 0.0166 0.0166
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0019 0.0019
Schistosoma mansoni metabotropic glutamate receptor 0.0098 0.0195 0.0195
Brugia malayi MH1 domain containing protein 0.0021 0.0026 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0019 0.0019
Giardia lamblia DINP protein human, muc B family 0.004 0.0067 0.0066
Onchocerca volvulus 0.0015 0.0014 0.0231
Loa Loa (eye worm) hypothetical protein 0.0149 0.0304 0.0304
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0019 0.0019
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0009 0.0001 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.02 0.0414 0.0414
Entamoeba histolytica Ran family GTPase 0.0014 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.002
Loa Loa (eye worm) Smad1 0.0021 0.0026 0.0026
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Echinococcus multilocularis GPCR, family 2 0.0032 0.005 0.005
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0111 0.0222 0.0222
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0298 0.0628 0.0628
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0033 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Mycobacterium ulcerans hypothetical protein 0.0018 0.0021 0.1376
Echinococcus multilocularis mothers against decapentaplegic 5 0.0021 0.0026 0.0026
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Schistosoma mansoni DNA polymerase IV / kappa 0.0012 0.0008 0.0008
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0018 0.0021 0.0316
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0023 0.0032 0.0032
Schistosoma mansoni inositol monophosphatase 0.0023 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Leishmania major protein kinase, putative 0.0019 0.0022 0.002
Echinococcus granulosus g-protein coupled receptor 0.0018 0.0019 0.0019
Onchocerca volvulus Neuropeptide F receptor homolog 0.0018 0.0019 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0045 0.008 0.1255
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Onchocerca volvulus 0.0033 0.0053 0.0846
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0046 0.0046
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0045 0.008 0.0079
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0023 0.003 0.0464
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0298 0.0628 0.0628
Onchocerca volvulus 0.0009 0.0001 0.002
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0298 0.0628 0.0628
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0033 0.0053 0.0053
Onchocerca volvulus Putative neutral sphingomyelinase 0.0009 0.0001 0.002
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0018 0.0021 0.002
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0045 0.008 0.1255
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0026 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Schistosoma mansoni gabp alpha 0.0044 0.0077 0.0077
Loa Loa (eye worm) runx1 0.0032 0.0051 0.0051
Brugia malayi Dopamine receptor 0.0018 0.0019 0.0019
Entamoeba histolytica hypothetical protein 0.0028 0.0042 0.0042
Brugia malayi hypothetical protein 0.0015 0.0014 0.0014
Schistosoma mansoni smad1 5 8 and 0.0021 0.0026 0.0026
Brugia malayi CCR4 0.0009 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Onchocerca volvulus 0.0018 0.002 0.0317
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0021 0.002
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Echinococcus multilocularis 0.0298 0.0628 0.0628
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0298 0.0628 0.0628
Echinococcus granulosus neuropeptide receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0011 0.0004 0.0004
Brugia malayi Intermediate filament tail domain containing protein 0.0016 0.0017 0.0017
Loa Loa (eye worm) TYRA-2 protein 0.0018 0.0019 0.0019
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0056 0.0103 0.0102
Loa Loa (eye worm) nuclear factor I 0.0011 0.0006 0.0006
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0015 0.0014 0.0014
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.003 0.003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Mycobacterium ulcerans lipase LipD 0.0023 0.003 0.2354
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0019 0.0019
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0875 0.1876 0.1875
Trypanosoma brucei unspecified product 0.004 0.0067 0.0066
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Schistosoma mansoni ap endonuclease 0.0045 0.008 0.008
Echinococcus granulosus dnaJ subfamily B 0.0253 0.053 0.053
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0018 0.0021 0.0316
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0018 0.0021 0.0316
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0056 0.0103 0.0103
Brugia malayi Cation transporter family protein 0.0033 0.0053 0.0053
Echinococcus granulosus hyperpolarization activated cyclic 0.0026 0.0038 0.0038
Brugia malayi MH1 domain containing protein 0.0011 0.0006 0.0006
Onchocerca volvulus Huntingtin homolog 0.0149 0.0304 0.4849
Giardia lamblia DNA damage repair protein 0.0012 0.0008 0.0007
Schistosoma mansoni hypothetical protein 0.0253 0.053 0.053
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0119 0.0238 0.0238
Mycobacterium tuberculosis Conserved hypothetical protein 0.0018 0.0021 0.0316
Echinococcus multilocularis snurportin 1 0.0198 0.0411 0.0411
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0008 0.0007
Echinococcus granulosus tachykinin peptides receptor 99D 0.0018 0.0019 0.0019
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0298 0.0628 0.0628
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0119 0.0238 0.0238
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0018 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0576 0.123 0.123
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0056 0.0103 0.0103
Brugia malayi G-protein coupled receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0015 0.0014 0.0014
Onchocerca volvulus Putative nachr subunit 0.0033 0.0053 0.0846
Trichomonas vaginalis PIKK family atypical protein kinase 0.2737 0.5908 0.5908
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0067 0.0066
Echinococcus granulosus 7TM GPCR rhodopsin 0.0018 0.0019 0.0019
Trypanosoma cruzi protein kinase A regulatory subunit 0.0018 0.0021 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0067 0.0066
Trypanosoma brucei importin beta-1 subunit, putative 0.0019 0.0022 0.002
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0045 0.008 0.0079
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0026 0.0038 0.0038
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0033 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Onchocerca volvulus 0.0015 0.0014 0.0231
Echinococcus multilocularis musashi 0.0016 0.0017 0.0017
Schistosoma mansoni smad1 5 8 and 0.0021 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.005
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0036 0.0036
Toxoplasma gondii hypothetical protein 0.0025 0.0036 0.0047
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0067 0.0067
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0018 0.0021 0.0021
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1551 0.3341 0.3341
Schistosoma mansoni amine GPCR 0.0018 0.0019 0.0019
Brugia malayi beta-lactamase 0.0023 0.003 0.003
Trichomonas vaginalis fk506-binding protein, putative 0.0056 0.0103 0.0103
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0026 0.0038 0.0038
Entamoeba histolytica hypothetical protein 0.0015 0.0014 0.0014
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0067 0.0067
Mycobacterium tuberculosis Probable lipase LipD 0.0023 0.003 0.0464
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0018 0.0021 0.0021
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0015 0.0014 0.0014
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Schistosoma mansoni 60S ribosomal protein L21 0.0018 0.0021 0.0021
Leishmania major phosphatidylinositol kinase related protein, putative 0.0298 0.0628 0.0627
Trichomonas vaginalis PIKK family atypical protein kinase 0.0298 0.0628 0.0628
Echinococcus granulosus glycine receptor subunit beta 0.0033 0.0053 0.0053
Echinococcus multilocularis G-protein coupled receptor, putative 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Onchocerca volvulus 0.0018 0.0021 0.0335
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0019 0.0019
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0199 0.0199
Schistosoma mansoni biogenic amine receptor 0.0018 0.0019 0.0019
Brugia malayi MH2 domain containing protein 0.0305 0.0642 0.0642
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0019 0.0019
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0036 0.0036
Trypanosoma cruzi Flagellar Member 6 0.0018 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0067 0.0066
Brugia malayi hypothetical protein 0.0015 0.0014 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.2494 0.5383 0.5383
Trichomonas vaginalis adenylate cyclase type, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) phosphatidylinositol kinase 0.0298 0.0628 0.0628
Echinococcus granulosus geminin 0.0499 0.1061 0.1061
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0018 0.0019 0.0019
Onchocerca volvulus 0.0016 0.0017 0.027
Brugia malayi Cation transporter family protein 0.0154 0.0316 0.0316
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0875 0.1876 0.1876
Brugia malayi hypothetical protein 0.0018 0.0019 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0008 0.0007
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.003 0.003
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0018 0.0021 0.0021
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.015 0.0306 0.0306
Leishmania major flap endonuclease-1 (FEN-1), putative 0.002 0.0025 0.0024
Brugia malayi polk-prov protein 0.0012 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0018 0.002 0.002
Echinococcus granulosus importin subunit beta 1 0.0019 0.0022 0.0022
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0676 0.1446 0.1446
Leishmania major GTP-binding protein, putative 0.0014 0.0011 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0067 0.0066
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0025 0.0036 0.0036
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Echinococcus multilocularis g-protein coupled receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0011 0.0004 0.0004
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0033 0.0053 0.0053
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0018 0.0021 0.0021
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.0425 0.0425
Toxoplasma gondii LsmAD domain-containing protein 0.002 0.0024 0.003
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0036 0.0036
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0021 0.0021
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0298 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.4626 1 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0059 0.011 0.0109
Schistosoma mansoni amine GPCR 0.0018 0.0019 0.0019
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0023 0.0032 0.0032
Schistosoma mansoni DNA polymerase eta 0.0059 0.011 0.011
Onchocerca volvulus 0.0018 0.0019 0.0308
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0009 0.0001 0.0001
Mycobacterium ulcerans regulatory protein 0.0018 0.0021 0.1376
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0033 0.0053 0.0053
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0298 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Loa Loa (eye worm) CXXC zinc finger family protein 0.0018 0.002 0.002
Leishmania major hypothetical protein, conserved 0.0018 0.0021 0.002
Schistosoma mansoni tar DNA-binding protein 0.0037 0.0061 0.0061
Echinococcus granulosus G protein coupled receptor 139 0.0018 0.0019 0.0019
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0036 0.0036
Echinococcus granulosus somatostatin receptor 0.0018 0.0019 0.0019
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0298 0.0628 0.0628
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0033 0.0053 0.0053
Echinococcus multilocularis dro:myosuppressin receptor 0.0018 0.0019 0.0019
Schistosoma mansoni immunophilin 0.0048 0.0086 0.0086
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0018 0.0019 0.0019
Echinococcus multilocularis synaptojanin 1 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0122 0.0245 0.0245
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0298 0.0628 0.0628
Brugia malayi putative neuropeptide receptor 0.0018 0.0019 0.0019
Leishmania major phosphatidylinositol 3-kinase, putative 0.0298 0.0628 0.0627
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0056 0.0103 0.0103
Mycobacterium ulcerans hypothetical protein 0.0018 0.0021 0.1376
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.4626 1 1
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0056 0.0103 0.1621
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0018 0.0021 0.0316
Trypanosoma brucei protein kinase, putative 0.0028 0.0042 0.0041
Schistosoma mansoni tar DNA-binding protein 0.0037 0.0061 0.0061
Trypanosoma brucei target of rapamycin kinase 3, putative 0.3683 0.7958 0.7958
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0036 0.0036
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0011 0.0004 0.0004
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0048 0.0086 0.0086
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0067 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0041 0.0039
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0009 0.0001 0.0001
Echinococcus granulosus GPCR family 2 0.0032 0.005 0.005
Leishmania major regulatory subunit of protein kinase a-like protein 0.0018 0.0021 0.002
Schistosoma mansoni ets-related 0.0135 0.0273 0.0273
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0037 0.0061 0.0061
Echinococcus granulosus orexin receptor type 2 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Brugia malayi hypothetical protein 0.0418 0.0887 0.0887
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0033 0.0053 0.0053
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0298 0.0628 0.0628
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0022 0.0022
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0009 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0067 0.0066
Echinococcus granulosus allatostatin A receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) flap endonuclease-1 0.002 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0499 0.1061 0.1061
Loa Loa (eye worm) hypothetical protein 0.0139 0.0283 0.0283
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0008 0.0007
Brugia malayi hypothetical protein 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Brugia malayi neuropeptide F receptor 0.0018 0.0019 0.0019
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Echinococcus granulosus serine protein kinase ATM 0.0875 0.1876 0.1876
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.003
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0018 0.0021 0.0021
Echinococcus granulosus lamin dm0 0.0016 0.0017 0.0017
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1551 0.3341 0.3341
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0021 0.0021
Echinococcus multilocularis tar DNA binding protein 0.0037 0.0061 0.0061
Loa Loa (eye worm) fli-1 protein 0.0135 0.0273 0.0273
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0298 0.0628 1
Echinococcus multilocularis serotonin transporter 0.015 0.0306 0.0306
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0026 0.0038 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0067 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.1551 0.3341 0.3341
Schistosoma mansoni cpg binding protein 0.0019 0.0022 0.0022
Onchocerca volvulus 0.0018 0.0019 0.0308
Echinococcus multilocularis orexin receptor type 2 0.0018 0.0019 0.0019
Treponema pallidum catabolite gene activator (Crp) 0.0018 0.0021 0.0649
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0013
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0056 0.0103 0.0102
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0298 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0033 0.0053 0.0053
Onchocerca volvulus 0.0016 0.0017 0.027
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0067 0.0066
Schistosoma mansoni immunophilin 0.0056 0.0103 0.0103
Mycobacterium leprae Probable lipase LipE 0.0023 0.003 0.0416
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.3003 0.6485 0.6485
Schistosoma mansoni nAChR subunit 0.0033 0.0053 0.0053
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0018 0.0021 0.0027
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0045 0.008 0.008
Onchocerca volvulus 0.0015 0.0014 0.0231
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.4626 1 1
Echinococcus multilocularis importin subunit beta 1 0.0019 0.0022 0.0022
Brugia malayi RNA, U transporter 1 0.0053 0.0096 0.0096
Trichomonas vaginalis CMGC family protein kinase 0.0028 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Echinococcus multilocularis deoxyribonuclease 1 2 0.0009 0.0001 0.0001
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0019 0.0019
Onchocerca volvulus 0.0018 0.0019 0.0308
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1551 0.3341 0.3341
Echinococcus granulosus snurportin 1 0.0198 0.0411 0.0411
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0198 0.0411 0.0411
Treponema pallidum catabolite gene activator 0.0018 0.0021 0.0649
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Toxoplasma gondii HEAT repeat-containing protein 0.0019 0.0022 0.0027
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.2188 0.4719 0.4719
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0061 0.0061
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0014 0.0011 0.0011
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0011 0.0004 0.0004
Echinococcus multilocularis Smad4 0.0021 0.0026 0.0026
Entamoeba histolytica hypothetical protein 0.0875 0.1876 0.1876
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0298 0.0628 0.0628
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0298 0.0628 0.0628
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0021 0.0026 0.0352
Brugia malayi Dopamine receptor protein 1 0.0018 0.0019 0.0019
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0298 0.0628 0.0628
Brugia malayi Pre-SET motif family protein 0.003 0.0046 0.0046
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0018 0.0019 0.0019
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0298 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Brugia malayi hypothetical protein 0.0257 0.0539 0.0539
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0032 0.003
Schistosoma mansoni myosin xvIII 0.0018 0.0019 0.0019
Echinococcus multilocularis Protein lozenge 0.0032 0.0051 0.0051
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0298 0.0628 0.0628
Trichomonas vaginalis adenylate cyclase type III, putative 0.0011 0.0004 0.0004
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0875 0.1876 0.1876
Trypanosoma cruzi target of rapamycin kinase 3 0.3683 0.7958 0.7958
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0298 0.0628 0.0843
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0046 0.0046
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0298 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0026 0.0038 0.0038
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0033 0.0053 0.0053
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0298 0.0628 0.0627
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0298 0.0628 0.0628
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1551 0.3341 0.334
Giardia lamblia Kinase, CMGC MAPK 0.0028 0.0042 0.0041
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0018 0.0021 0.0021
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.003
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Schistosoma mansoni ran 0.0014 0.0011 0.0011
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0023 0.0032 0.0041
Leishmania major phosphatidylinositol 3-kinase, putative 0.1551 0.3341 0.334
Echinococcus granulosus serotonin receptor 0.0018 0.0019 0.0019
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0298 0.0628 0.0843
Loa Loa (eye worm) ACC-1 protein 0.0033 0.0053 0.0053
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0036 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.368 0.795 0.795
Trypanosoma brucei unspecified product 0.0027 0.0041 0.0039
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0033 0.0053 0.0053
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0298 0.0628 0.0628
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0009 0.0001 0.0001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0298 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Schistosoma mansoni nAChR subunit 0.0033 0.0053 0.0053
Echinococcus granulosus GA binding protein alpha chain 0.0044 0.0077 0.0077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0019 0.0019
Brugia malayi Serotonin receptor 0.0018 0.0019 0.0019
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.005 0.005
Mycobacterium tuberculosis Probable hydrolase 0.0023 0.003 0.0464
Trichomonas vaginalis PIKK family atypical protein kinase 0.3441 0.7433 0.7433
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0298 0.0628 0.0628
Treponema pallidum sodium- and chloride- dependent transporter 0.015 0.0306 1
Toxoplasma gondii ABC1 family protein 0.0023 0.003 0.0039
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0067 0.0066
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0067 0.0066
Echinococcus granulosus cGMP dependent protein kinase 1 0.0019 0.0022 0.0022
Trichomonas vaginalis set domain proteins, putative 0.0233 0.0486 0.0486
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.0008 0.0009
Loa Loa (eye worm) phosphatidylinositol 3 0.0298 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Brugia malayi Sodium:neurotransmitter symporter family protein 0.015 0.0306 0.0306
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0298 0.0628 0.0628
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0154 0.0316 0.0316
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0019 0.0019
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0018 0.0021 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0042 0.0042
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0033 0.0053 0.0053
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0036 0.0047
Onchocerca volvulus 0.0018 0.0019 0.0308
Echinococcus granulosus neuropeptide FF receptor 2 0.0018 0.0019 0.0019
Schistosoma mansoni smad 0.0009 0.0002 0.0002
Brugia malayi beta-lactamase family protein 0.0023 0.003 0.003
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0019 0.0019
Brugia malayi Fli-1 protein 0.0135 0.0273 0.0273
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.005 0.005
Leishmania major hypothetical protein, conserved 0.002 0.0024 0.0023
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0011 0.0004 0.0004
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0033 0.0053 0.0053
Echinococcus granulosus neuropeptide s receptor 0.0018 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0676 0.1446 0.1446
Trichomonas vaginalis PIKK family atypical protein kinase 0.3441 0.7433 0.7433
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Treponema pallidum cyclic nucleotide binding protein 0.0018 0.0021 0.0649
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0298 0.0628 0.0628
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0015 0.0014 0.0014
Brugia malayi ORL1-like opioid receptor 0.0018 0.0019 0.0019
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0018 0.0019 0.0019
Onchocerca volvulus 0.0018 0.0019 0.0308
Trichomonas vaginalis Phospholipase C precursor, putative 0.0009 0.0001 0.0001
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0056 0.0103 0.0102
Loa Loa (eye worm) inositol-1 0.0023 0.0032 0.0032
Mycobacterium ulcerans hypothetical protein 0.0018 0.0021 0.1376
Mycobacterium tuberculosis Conserved hypothetical protein 0.0298 0.0628 1
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0021
Loa Loa (eye worm) acetylcholine receptor protein 0.0015 0.0014 0.0014
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0875 0.1876 0.1876
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0018 0.0019 0.0019
Onchocerca volvulus 0.0025 0.0036 0.0581
Trichomonas vaginalis PIKK family atypical protein kinase 0.368 0.795 0.795
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0018 0.0021 0.0021
Loa Loa (eye worm) MH2 domain-containing protein 0.0009 0.0002 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0037 0.0061 0.0061
Mycobacterium ulcerans hypothetical protein 0.0023 0.003 0.2354
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0009 0.0001 0.0001
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0014 0.0011 0.001
Schistosoma mansoni hypothetical protein 0.0018 0.0019 0.0019
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0019 0.0019
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0051 0.0067
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0018 0.0021 0.0316
Brugia malayi hypothetical protein 0.0018 0.0019 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0041 0.0039
Schistosoma mansoni immunophilin 0.0056 0.0103 0.0103
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0018 0.0019 0.0019
Entamoeba histolytica hypothetical protein 0.0028 0.0042 0.0042
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0019 0.0019
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0298 0.0628 0.0627
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0046 0.0046
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0037 0.0061 0.0061
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Echinococcus multilocularis neuropeptide receptor A26 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0021
Brugia malayi Latrophilin receptor protein 2 0.0032 0.005 0.005
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0298 0.0628 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Echinococcus multilocularis geminin 0.0499 0.1061 0.1061
Loa Loa (eye worm) hypothetical protein 0.0943 0.2023 0.2023
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0028 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Schistosoma mansoni nAChR subunit 0.0033 0.0053 0.0053
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0144 0.0294 0.4672
Giardia lamblia Flap structure-specific endonuclease 0.002 0.0025 0.0024
Onchocerca volvulus 0.0018 0.0019 0.0308
Schistosoma mansoni voltage-gated potassium channel 0.0129 0.0262 0.0262
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0119 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Loa Loa (eye worm) transcription factor SMAD2 0.0305 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0056 0.0103 0.0102
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Schistosoma mansoni Smad4 0.0021 0.0026 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.395 0.8535 0.8535
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0298 0.0628 0.0843
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0033 0.0053 0.0053
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0067 0.0067
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0298 0.0628 0.0628
Brugia malayi larval opioid receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.368 0.795 0.795
Loa Loa (eye worm) phosphatidylinositol 3 0.0298 0.0628 0.0628
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0018 0.0021 0.0021
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.2498 0.5391 0.5391
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0875 0.1876 0.1875
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.02 0.0414 0.0414
Loa Loa (eye worm) phosphatidylinositol 3 0.4626 1 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0019 0.0019
Brugia malayi neuropeptide F receptor 0.0018 0.0019 0.0019
Leishmania major hypothetical protein, conserved 0.0023 0.003 0.0029
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0018 0.002 0.002
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.002
Entamoeba histolytica hypothetical protein 0.0298 0.0628 0.0628
Echinococcus granulosus metabotropic glutamate receptor 5 0.0015 0.0013 0.0013
Schistosoma mansoni opsin-like receptor 0.0018 0.0019 0.0019
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0033 0.0053 0.0053
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0009 0.0001 0.0001
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.002 0.0025 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.2764 0.5968 0.5968
Brugia malayi Ets-domain containing protein 0.0044 0.0077 0.0077
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0576 0.123 0.1229
Schistosoma mansoni cript-related 0.0009 0.0001 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0019 0.0019
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0015 0.0014 0.0014
Echinococcus multilocularis dnaJ subfamily B 0.0253 0.053 0.053
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0298 0.0628 0.0627
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Trichomonas vaginalis hypothetical protein 0.0011 0.0004 0.0004
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0257 0.0539 0.0539
Schistosoma mansoni hypothetical protein 0.0018 0.0019 0.0019
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0019 0.0019
Onchocerca volvulus 0.0233 0.0486 0.7739
Echinococcus granulosus mothers against decapentaplegic 5 0.0021 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0975 0.2093 0.2093
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0033 0.0053 0.0053
Brugia malayi N-terminal motif family protein 0.0156 0.0319 0.0319
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0018 0.0019 0.0019
Brugia malayi Tachykinin-like peptides receptor 99D 0.0018 0.0019 0.0019
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0298 0.0628 0.0843
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0018 0.0021 0.002
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0044 0.0077 0.0077
Echinococcus granulosus GTP binding nuclear protein Ran 0.0014 0.0011 0.0011
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0011 0.0004 0.0004
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.002 0.0025 0.0032
Brugia malayi G-protein coupled receptor 0.0018 0.0019 0.0019
Brugia malayi sulfakinin receptor protein 0.0122 0.0245 0.0245
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0018 0.0019 0.0308
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Echinococcus multilocularis sex peptide receptor 0.0018 0.0019 0.0019
Plasmodium vivax importin-beta 2, putative 0.0019 0.0022 0.0325
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.003 0.0029
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0298 0.0628 0.0627
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.1551 0.3341 0.334
Schistosoma mansoni hypothetical protein 0.0018 0.0019 0.0019
Brugia malayi hypothetical protein 0.0013 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Trypanosoma brucei cAMP binding protein, putative 0.0018 0.0021 0.002
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0056 0.0103 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0022 0.0022
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0014 0.0011 0.0156
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0046 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.2494 0.5383 0.5383
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0019 0.0019
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0059 0.011 0.011
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0018 0.0021 0.0021
Treponema pallidum cyclic nucleotide binding protein 0.0018 0.0021 0.0649
Schistosoma mansoni amine GPCR 0.0018 0.0019 0.0019
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0056 0.0103 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0576 0.123 0.123
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0026 0.0038 0.0038
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0033 0.0053 0.0053
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0019 0.0019
Schistosoma mansoni nAChR subunit 0.0033 0.0053 0.0053
Plasmodium vivax flap endonuclease 1, putative 0.002 0.0025 0.0384
Trypanosoma cruzi cAMP binding protein, putative 0.0018 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.4626 1 1
Onchocerca volvulus 0.0154 0.0316 0.503
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Brugia malayi Cation transporter family protein 0.0033 0.0053 0.0053
Leishmania major DNA polymerase eta, putative 0.0059 0.011 0.0109
Schistosoma mansoni hypothetical protein 0.0011 0.0004 0.0004
Schistosoma mansoni growth hormone secretagogue receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0033 0.0053 0.0053
Echinococcus multilocularis GA binding protein alpha chain 0.0044 0.0077 0.0077
Toxoplasma gondii exonuclease III APE 0.0045 0.008 0.0106
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0056 0.0103 1
Mycobacterium leprae conserved hypothetical protein 0.0298 0.0628 1
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.003 0.003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0046 0.0046
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0032 0.003
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0018 0.0021 0.0027
Plasmodium falciparum amino acid transporter, putative 0.0025 0.0036 0.0562
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Schistosoma mansoni neuropeptide receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) MH1 domain-containing protein 0.0021 0.0026 0.0026
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0019 0.0019
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0037 0.0061 0.0061
Leishmania major fk506-binding protein 1-like protein 0.0056 0.0103 0.0102
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0298 0.0628 0.0628
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0026 0.0038 0.0038
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0033 0.0053 0.0053
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0024 0.0362
Onchocerca volvulus 0.0298 0.0628 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0018 0.0019 0.0019
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0018 0.0019 0.0019
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0067 0.0066
Schistosoma mansoni amine GPCR 0.0111 0.0221 0.0221
Plasmodium falciparum DNA repair protein REV1, putative 0.0012 0.0008 0.0107
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.005 0.005
Mycobacterium ulcerans hypothetical protein 0.0018 0.0021 0.1376
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0033 0.0053 0.0053
Onchocerca volvulus 0.0018 0.0019 0.0308
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0298 0.0628 0.0628
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0067 0.0066
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Plasmodium vivax DNA repair protein REV1, putative 0.0012 0.0008 0.0107
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Onchocerca volvulus 0.0154 0.0316 0.503
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.1921 0.4143 0.4142
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0033 0.0053 0.0053
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0009 0.0001 0.0001
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0067 0.6238
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0032 0.003
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0056 0.0103 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.1551 0.3341 0.3341
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0018 0.0021 0.0021
Brugia malayi Serotonin receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Echinococcus granulosus glycine receptor subunit beta 0.0033 0.0053 0.0053
Mycobacterium tuberculosis Probable esterase LipL 0.0023 0.003 0.0464
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0056 0.0103 0.1621
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0298 0.0628 0.0628
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.01 0.0199 0.0199
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0041 0.0039
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0033 0.0053 0.0053
Schistosoma mansoni sodium/chloride dependent transporter 0.0026 0.0037 0.0037
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0018 0.0019 0.0019
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0011 0.0004 0.0004
Mycobacterium leprae Conserved hypothetical protein 0.0018 0.0021 0.0267
Schistosoma mansoni neuropeptide receptor 0.0018 0.0019 0.0019
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0036 0.0047
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0026 0.0038 0.0038
Echinococcus granulosus dna polymerase kappa 0.004 0.0067 0.0067
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0067 0.0067
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0019 0.0019
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.4626 1 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.003 0.0029
Brugia malayi hypothetical protein 0.0018 0.0019 0.0019
Leishmania major hypothetical protein, conserved 0.0298 0.0628 0.0627
Brugia malayi excitatory GABA receptor EXP-1A 0.0033 0.0053 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0154 0.0316 0.0316
Brugia malayi Egg laying defective protein 4 0.0019 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0298 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0018 0.0021 0.0021
Echinococcus granulosus hyperpolarization activated cyclic 0.0026 0.0038 0.0038
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0036 0.0036
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0018 0.0021 0.0316
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0036 0.0036
Echinococcus multilocularis smad 0.0021 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Brugia malayi exodeoxyribonuclease III family protein 0.0045 0.008 0.008
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0017
Onchocerca volvulus 0.0033 0.0053 0.0846
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) melatonin receptor type 1A 0.0018 0.0019 0.0019
Echinococcus granulosus nAChR subunit 0.0018 0.002 0.002
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0014 0.0011 0.001
Schistosoma mansoni tar DNA-binding protein 0.0037 0.0061 0.0061
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0298 0.0628 0.0628
Echinococcus granulosus g protein coupled receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Echinococcus granulosus neuropeptide receptor 0.0018 0.0019 0.0019
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0298 0.0628 0.0628
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0056 0.0103 0.0103
Leishmania major hypothetical protein, conserved 0.0018 0.0021 0.002
Echinococcus granulosus sex peptide receptor 0.0018 0.0019 0.0019
Echinococcus multilocularis Zinc finger, PHD finger 0.0298 0.0628 0.0628
Mycobacterium tuberculosis Conserved protein 0.0018 0.0021 0.0316
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0028 0.0042 0.0042
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0045 0.008 0.0079
Brugia malayi TAR-binding protein 0.0037 0.0061 0.0061
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.0051 0.005
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0018 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.2764 0.5968 0.5968
Onchocerca volvulus 0.0025 0.0036 0.0581
Schistosoma mansoni lamin 0.0016 0.0017 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.02 0.0414 0.0414
Toxoplasma gondii hypothetical protein 0.0025 0.0036 0.0047
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0298 0.0628 0.0627
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0025 0.0036 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0045 0.008 0.0079
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0008 0.0009
Schistosoma mansoni biogenic amine receptor 0.0018 0.0019 0.0019
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0018 0.0019 0.0019
Schistosoma mansoni carbon catabolite repressor protein 0.0009 0.0001 0.0001
Leishmania major DNA polymerase eta, putative 0.0032 0.0051 0.005
Trichomonas vaginalis CMGC family protein kinase 0.0028 0.0042 0.0042
Echinococcus granulosus alpha 1A adrenergic receptor 0.0018 0.0019 0.0019
Onchocerca volvulus 0.0154 0.0316 0.503
Leishmania major cyclic nucleotide-binding protein-like protein 0.0018 0.0021 0.002
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0021 0.0026 0.0026
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0298 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0056 0.0103 0.0102
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0033 0.0053 0.0053
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0033 0.0053 0.0053
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.3441 0.7433 0.7433
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Giardia lamblia GTOR 0.4626 1 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0045 0.008 0.258
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0008 0.0007
Schistosoma mansoni nocturnin 0.0009 0.0001 0.0001
Schistosoma mansoni sodium/chloride dependent transporter 0.0025 0.0036 0.0036
Echinococcus granulosus neutral sphingomyelinase 0.0009 0.0001 0.0001
Loa Loa (eye worm) MH2 domain-containing protein 0.0305 0.0642 0.0642
Echinococcus multilocularis lamin dm0 0.0016 0.0017 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.02 0.0414 0.0414
Echinococcus granulosus survival motor neuron protein 1 0.0418 0.0887 0.0887
Echinococcus multilocularis voltage gated potassium channel 0.0037 0.0061 0.0061
Onchocerca volvulus 0.0018 0.0019 0.0308
Brugia malayi hypothetical protein 0.0018 0.0019 0.0019
Brugia malayi Melatonin receptor type 1A 0.0018 0.0019 0.0019
Trichomonas vaginalis immunophilin, putative 0.0056 0.0103 0.0103
Echinococcus multilocularis mothers against decapentaplegic 2 0.0009 0.0002 0.0002
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0257 0.0539 0.0539
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0023 0.0032 0.2487
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0019 0.0019
Brugia malayi Smad1 0.0021 0.0026 0.0026
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0018 0.0019 0.0019
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0036 0.0036
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0036 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0022 0.0022
Onchocerca volvulus 0.0018 0.002 0.0319
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0676 0.1446 0.1446
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0067 0.0066
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0298 0.0628 0.0628
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0033 0.0053 0.0053
Trypanosoma cruzi cAMP response protein 1 0.0018 0.0021 0.002
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0033 0.0053 0.0053
Echinococcus granulosus tm gpcr rhodopsin 0.0446 0.0946 0.0946
Echinococcus multilocularis lamin 0.0016 0.0017 0.0017
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Onchocerca volvulus 0.0023 0.003 0.0483
Trichomonas vaginalis PIKK family atypical protein kinase 0.3441 0.7433 0.7433
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0033 0.0053 0.0053
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0067 0.1051
Schistosoma mansoni tar DNA-binding protein 0.0037 0.0061 0.0061
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0011 0.0005 0.0004
Trichomonas vaginalis inositol monophosphatase, putative 0.0023 0.0032 0.0032
Loa Loa (eye worm) glutamate receptor 0.0012 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.2498 0.5391 0.5391
Onchocerca volvulus 0.0085 0.0166 0.2647
Trichomonas vaginalis PIKK family atypical protein kinase 0.2494 0.5383 0.5383
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0024 0.0023
Onchocerca volvulus 0.0009 0.0001 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0875 0.1876 0.1876
Echinococcus granulosus fmrfamide receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1551 0.3341 0.3341
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0028 0.0042 0.0041
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Trypanosoma brucei PAB1-binding protein , putative 0.002 0.0024 0.0023
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0028 0.0042 0.0041
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0298 0.0628 0.0628
Schistosoma mansoni voltage-gated potassium channel 0.0026 0.0038 0.0038
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0024 0.0362
Echinococcus granulosus glycine receptor subunit alpha 1 0.0033 0.0053 0.0053
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0025 0.0036 0.0036
Echinococcus granulosus cGMP dependent protein kinase 1 0.0019 0.0022 0.0022
Brugia malayi metabotropic glutamate receptor type 2 0.0015 0.0013 0.0013
Onchocerca volvulus 0.0018 0.0021 0.0335
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0036 0.0562
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Trypanosoma brucei Flagellar Member 6 0.0018 0.0021 0.002
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0011 0.0004 0.0004
Brugia malayi hypothetical protein 0.0018 0.0019 0.0019
Schistosoma mansoni alpha-1 adrenergic receptor 0.0018 0.0019 0.0019
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0033 0.0053 0.0053
Echinococcus multilocularis mitogen activated protein kinase 0.0028 0.0042 0.0042
Echinococcus multilocularis mitogen activated protein kinase 3 0.0028 0.0042 0.0042
Leishmania major DNA damage repair protein, putative 0.0012 0.0008 0.0007
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0026 0.0038 0.0038
Echinococcus multilocularis cpg binding protein 0.0019 0.0022 0.0022
Leishmania major protein kinase, putative 0.0019 0.0022 0.002
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0015 0.0014 0.0014
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0119 0.0238 0.0238
Trichomonas vaginalis PIKK family atypical protein kinase 0.1241 0.2669 0.2669
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0045 0.008 0.7582
Brugia malayi hypothetical protein 0.0028 0.0042 0.0042
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0025 0.0036 0.0036
Echinococcus multilocularis inositol monophosphatase 1 0.0023 0.0032 0.0032
Brugia malayi RNA binding protein 0.0037 0.0061 0.0061
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0298 0.0628 0.0627
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0018 0.0021 0.0316
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0038 0.0064 0.0064
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0015 0.0014 0.0014
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0067 0.0067
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0023 0.003 0.003
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0011 0.0004 0.0004
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0015 0.0014 0.0014
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0023 0.003 0.2354
Echinococcus granulosus neuropeptide receptor A26 0.0018 0.0019 0.0019
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0298 0.0628 0.0628
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0298 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0011 0.0004 0.0004
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0036 0.0036
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.4626 1 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0298 0.0628 0.0628
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0056 0.0103 0.0103
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0009 0.0001 0.0001
Brugia malayi FAT domain containing protein 0.0676 0.1446 0.1446
Echinococcus granulosus dro:myosuppressin receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.002
Schistosoma mansoni sodium-dependent amino acid transporter 0.0025 0.0036 0.0036
Onchocerca volvulus 0.0033 0.0053 0.0846
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0015 0.0014 0.0014
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0026 0.0038 0.0038
Loa Loa (eye worm) TAR-binding protein 0.0037 0.0061 0.0061
Mycobacterium tuberculosis Conserved hypothetical protein 0.0018 0.0021 0.0316
Trypanosoma cruzi cAMP response protein 1, putative 0.0018 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0019 0.0019
Schistosoma mansoni neurotransmitter gated ion channel 0.0015 0.0014 0.0014
Trypanosoma brucei importin beta-1 subunit, putative 0.0019 0.0022 0.002
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Brugia malayi G protein-coupled receptor F59B2.13 0.0018 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0069 0.013 0.013
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0014 0.0011 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.3441 0.7433 0.7433
Echinococcus granulosus synaptojanin 1 0.0009 0.0001 0.0001
Trichomonas vaginalis adenylate cyclase type, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis flap endonuclease-1, putative 0.002 0.0025 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.2498 0.5391 0.5391
Echinococcus granulosus beta LACTamase domain containing family member 0.0023 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0418 0.0887 0.0887
Loa Loa (eye worm) hypothetical protein 0.015 0.0306 0.0306
Echinococcus granulosus voltage gated potassium channel 0.0037 0.0061 0.0061
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0018 0.0019 0.0019
Schistosoma mansoni neurotransmitter gated ion channel 0.0015 0.0014 0.0014
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.02 0.0414 0.0414
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0011 0.0004 0.0004
Schistosoma mansoni adenoreceptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0021 0.0026 0.0026
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0018 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0676 0.1446 0.1446
Schistosoma mansoni hypothetical protein 0.0298 0.0628 0.0628
Schistosoma mansoni neurotransmitter gated ion channel 0.0018 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Schistosoma mansoni synaptojanin 0.0009 0.0001 0.0001
Schistosoma mansoni neuropeptide receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1551 0.3341 0.334
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.003 0.0046 0.0046
Brugia malayi MH2 domain containing protein 0.0021 0.0026 0.0026
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0026 0.0038 0.0038
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0045 0.008 0.0079
Schistosoma mansoni amine GPCR 0.0018 0.0019 0.0019
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0024 0.0023
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0028 0.0042 0.0041
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0015 0.0014 0.0014
Plasmodium falciparum transporter, putative 0.0025 0.0036 0.0562
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0009 0.0001 0.0001
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0036 0.0036
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Echinococcus multilocularis glycine receptor subunit beta 0.0033 0.0053 0.0053
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0018 0.0019 0.0019
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0033 0.0053 0.0053
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0298 0.0628 0.0627
Leishmania major peptidylprolyl isomerase-like protein 0.0056 0.0103 0.0102
Echinococcus granulosus g protein coupled receptor 0.0018 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0028 0.0042 0.0042
Schistosoma mansoni inositol monophosphatase 0.0023 0.0032 0.0032
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0018 0.0021 0.0021
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0298 0.0628 0.0627
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0875 0.1876 0.1876
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0046 0.0046
Leishmania major importin beta-1 subunit, putative 0.0015 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Brugia malayi MH1 domain containing protein 0.0021 0.0026 0.0026
Trichomonas vaginalis ap endonuclease, putative 0.0045 0.008 0.008
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.3683 0.7958 0.7958
Plasmodium vivax SET domain protein, putative 0.003 0.0046 0.0709
Trichomonas vaginalis CMGC family protein kinase 0.0028 0.0042 0.0042
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0271 0.0568 0.0568
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0018 0.0021 0.0021
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0019 0.0019
Brugia malayi GnHR receptor homolog 0.0018 0.0019 0.0019
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0009 0.0001 0.0001
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0298 0.0628 0.0628
Trichomonas vaginalis penicillin-binding protein, putative 0.0023 0.003 0.003
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0298 0.0628 0.0627
Echinococcus multilocularis serotonin receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0033 0.0053 0.0053
Entamoeba histolytica Flap nuclease, putative 0.002 0.0025 0.0025
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0011 0.0004 0.0004
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0023 0.0032 0.0032
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0019 0.0022 0.0022
Onchocerca volvulus 0.0018 0.0019 0.0308
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0026 0.0038 0.0038
Echinococcus granulosus g protein coupled receptor 0.0018 0.0019 0.0019
Onchocerca volvulus 0.003 0.0046 0.0728
Trichomonas vaginalis importin beta-1, putative 0.0015 0.0014 0.0014
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0067 0.1051
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0056 0.0103 0.0103
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0018 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0875 0.1876 0.1876
Giardia lamblia DNA repair protein RAD52 0.0271 0.0568 0.0567
Loa Loa (eye worm) phosphatidylinositol 3 0.0298 0.0628 0.0628
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.002 0.002
Echinococcus granulosus TGF beta signal transducer SmadC 0.0021 0.0026 0.0026
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.002 0.002
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0056 0.0103 0.0103
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0036 0.0036
Plasmodium vivax hypothetical protein, conserved 0.0298 0.0628 1
Leishmania major protein kinase A regulatory subunit, putative 0.0018 0.0021 0.002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0033 0.0053 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.003 0.0029
Brugia malayi CXXC zinc finger family protein 0.0018 0.002 0.002
Brugia malayi MH2 domain containing protein 0.0021 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0008
Onchocerca volvulus 0.0023 0.003 0.0483
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0028 0.0042 0.0041
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0298 0.0628 0.0628
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0298 0.0628 0.0628
Echinococcus granulosus mitogen activated protein kinase 3 0.0028 0.0042 0.0042
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0298 0.0628 0.0627
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Echinococcus multilocularis serotonin receptor 0.0018 0.0019 0.0019
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.4626 1 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0016
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0028 0.0042 0.0041
Brugia malayi MH2 domain containing protein 0.0009 0.0002 0.0002
Trypanosoma brucei chrX additional, unordered contigs 0.0012 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0298 0.0628 0.0843
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0026 0.0038 0.0038
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0298 0.0628 0.0628
Brugia malayi Pre-SET motif family protein 0.0205 0.0425 0.0425
Trichomonas vaginalis adenylate cyclase type III, putative 0.0011 0.0004 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.0085 0.0166 0.0166
Plasmodium falciparum importin beta, putative 0.0019 0.0022 0.0325
Loa Loa (eye worm) hypothetical protein 0.0101 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.002
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0009 0.0001 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.02 0.0414 0.0414
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0111 0.0222 0.0222
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0019 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0019 0.0019
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0019 0.0019
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0014 0.0011 0.0156
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.1551 0.3341 0.3341
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.002
Brugia malayi hypothetical protein 0.0149 0.0304 0.0304
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0298 0.0628 0.0628
Leishmania major hypothetical protein, conserved 0.0018 0.0021 0.002
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0033 0.0053 0.0053
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0018 0.0019 0.0019
Schistosoma mansoni nAChR subunit 0.0015 0.0014 0.0014
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) MH2 domain-containing protein 0.0021 0.0026 0.0026
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0015 0.0014 0.0014
Echinococcus granulosus cpg binding protein 0.0019 0.0022 0.0022
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0067 0.6238
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0019 0.0022 0.0027
Trichomonas vaginalis guanylate cyclase, putative 0.0011 0.0004 0.0004
Echinococcus multilocularis beta LACTamase domain containing family member 0.0023 0.003 0.003
Onchocerca volvulus 0.0023 0.003 0.0483
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Onchocerca volvulus 0.015 0.0306 0.4873
Loa Loa (eye worm) AGC/PKG protein kinase 0.0019 0.0022 0.0022
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0028 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Echinococcus granulosus Smad4 0.0021 0.0026 0.0026
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0033 0.0053 0.0053
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0018 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0149 0.0304 0.0304
Echinococcus granulosus patatin phospholipase domain containing protein 0.0018 0.0021 0.0021
Trypanosoma brucei unspecified product 0.0027 0.0041 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Brugia malayi AKH receptor 0.0018 0.0019 0.0019
Brugia malayi intermediate filament protein 0.0016 0.0017 0.0017
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.2498 0.5391 0.5391
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0008 0.0007
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0009 0.0001 0.0001
Loa Loa (eye worm) serotonin transporter b 0.015 0.0306 0.0306
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0008 0.0007
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0019 0.0019
Loa Loa (eye worm) FKBP5 protein 0.0056 0.0103 0.0103
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0298 0.0628 0.0627
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0298 0.0628 0.0628
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Toxoplasma gondii FATC domain-containing protein 0.0875 0.1876 0.2523
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0018 0.0021 0.002
Loa Loa (eye worm) norepinephrine transporter 0.015 0.0306 0.0306
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0019 0.0019
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0023 0.003 0.0464
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0875 0.1876 0.1876
Trypanosoma brucei cAMP response protein 1, putative 0.0018 0.0021 0.002
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0048 0.0086 0.0086
Plasmodium vivax amine transporter, putative 0.0025 0.0036 0.0562
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0033 0.0053 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0019 0.0019
Echinococcus multilocularis somatostatin receptor 0.0018 0.0019 0.0019
Schistosoma mansoni Smad4 0.0009 0.0002 0.0002
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0014 0.0011 0.0013
Onchocerca volvulus Huntingtin homolog 0.0149 0.0304 0.4849
Loa Loa (eye worm) GABA receptor subunit 0.0018 0.002 0.002
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0298 0.0628 0.0627
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0019 0.0022 0.0022
Mycobacterium tuberculosis Conserved protein 0.0023 0.003 0.0464
Leishmania major DNA polymerase kappa, putative 0.004 0.0067 0.0066
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0014 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Echinococcus multilocularis nAChR subunit 0.0033 0.0053 0.0053
Echinococcus multilocularis fk506 binding protein 0.0056 0.0103 0.0103
Onchocerca volvulus 0.0018 0.0019 0.0308
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.015 0.0306 0.0306
Echinococcus multilocularis dna polymerase kappa 0.004 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Echinococcus granulosus traf and tnf receptor associated protein 0.0009 0.0001 0.0001
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0018 0.0019 0.0019
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0026 0.0038 0.0038
Echinococcus multilocularis glycine receptor subunit beta 0.0033 0.0053 0.0053
Leishmania major phosphatidylinositol kinase, putative 0.0298 0.0628 0.0627
Leishmania major phosphatidylinositol 3-related kinase, putative 0.1551 0.3341 0.334
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Mycobacterium ulcerans beta-lactamase 0.0023 0.003 0.2354
Loa Loa (eye worm) phosphatidylinositol 3 0.1551 0.3341 0.3341
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0033 0.0053 0.0053
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0028 0.0042 0.0041
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0028 0.0042 0.0041
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0011 0.0004 0.0004
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0009 0.0001 0.0001
Toxoplasma gondii target of rapamycin (TOR), putative 0.3441 0.7433 1
Plasmodium vivax hypothetical protein 0.0298 0.0628 1
Entamoeba histolytica hypothetical protein 0.0298 0.0628 0.0628
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0019 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.003
Entamoeba histolytica hypothetical protein 0.0028 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0975 0.2093 0.2814
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.002 0.0025 0.0024
Schistosoma mansoni smad 0.0021 0.0026 0.0026
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0023 0.003 0.0464
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0019
Brugia malayi Inositol-1 0.0023 0.0032 0.0032
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0019 0.0019
Echinococcus granulosus dna polymerase eta 0.0059 0.011 0.011
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0018 0.002 0.002
Echinococcus granulosus glycine receptor subunit alpha 1 0.0033 0.0053 0.0053
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.4626 1 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.003
Brugia malayi MH1 domain containing protein 0.0011 0.0006 0.0006
Echinococcus multilocularis G protein coupled receptor 139 0.0018 0.0019 0.0019
Schistosoma mansoni lamin 0.0016 0.0017 0.0017
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0018 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Echinococcus multilocularis survival motor neuron protein 1 0.0418 0.0887 0.0887
Giardia lamblia Phosphatidylinositol 4-kinase 0.0298 0.0628 0.0627
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0018 0.0021 0.0027
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0875 0.1876 0.1875
Trichomonas vaginalis conserved hypothetical protein 0.0975 0.2093 0.2093
Trypanosoma brucei DNA polymerase eta, putative 0.0059 0.011 0.0109
Plasmodium falciparum cGMP-dependent protein kinase 0.0019 0.0022 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.3103 0.6702 0.6702
Loa Loa (eye worm) hypothetical protein 0.0298 0.0628 0.0628
Echinococcus multilocularis expressed conserved protein 0.0019 0.0022 0.0022
Echinococcus multilocularis allatostatin A receptor 0.0018 0.0019 0.0019
Echinococcus granulosus intermediate filament protein 0.0016 0.0017 0.0017
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0018 0.0019 0.0019
Leishmania major DNA polymerase kappa, putative 0.0012 0.0008 0.0007
Schistosoma mansoni opsin-like receptor 0.0018 0.0019 0.0019
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0061 0.0061
Schistosoma mansoni flap endonuclease-1 0.0018 0.0021 0.0021
Brugia malayi hypothetical protein 0.0025 0.0036 0.0036
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0056 0.0103 0.0102
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0009 0.0001 0.0001
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0298 0.0628 0.0628
Brugia malayi hypothetical protein 0.0015 0.0014 0.0014
Echinococcus multilocularis serine protein kinase ATM 0.0875 0.1876 0.1876
Brugia malayi hypothetical protein 0.0015 0.0014 0.0014
Leishmania major phosphatidylinositol 4-kinase, putative 0.0298 0.0628 0.0627
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0298 0.0628 0.0627
Schistosoma mansoni hypothetical protein 0.0198 0.0411 0.0411
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0016 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.0028 0.0042 0.0042
Schistosoma mansoni neuropeptide f receptor 76f 0.0018 0.0019 0.0019
Giardia lamblia Hypothetical protein 0.0298 0.0628 0.0627
Brugia malayi Importin beta-1 subunit 0.0019 0.0022 0.0022
Schistosoma mansoni ran 0.0014 0.0011 0.0011
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0298 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0069 0.013 0.013
Echinococcus granulosus nAChR subunit 0.0033 0.0053 0.0053
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0018 0.0019 0.0019
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Brugia malayi ImpB/MucB/SamB family protein 0.0059 0.011 0.011
Brugia malayi Flap endonuclease-1 0.002 0.0025 0.0025
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0154 0.0316 0.0316
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0026 0.0038 0.0038
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0019 0.0019
Brugia malayi MAP kinase sur-1 0.0028 0.0042 0.0042
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0026 0.0038 0.0038
Entamoeba histolytica hypothetical protein 0.0077 0.0148 0.0148
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0067 0.0066
Schistosoma mansoni ap endonuclease 0.0045 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0676 0.1446 0.1446
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0067 0.0066
Trichomonas vaginalis adenylate cyclase, putative 0.0011 0.0004 0.0004
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0018 0.0021 0.0021
Toxoplasma gondii histone lysine methyltransferase SET1 0.0035 0.0057 0.0075
Plasmodium vivax hypothetical protein, conserved 0.0023 0.003 0.0464
Schistosoma mansoni hypothetical protein 0.0032 0.005 0.005
Schistosoma mansoni nAChR subunit 0.0033 0.0053 0.0053
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0025 0.0036 0.0036
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0015 0.0014 0.0014
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0015 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.003
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0298 0.0628 0.0628
Trichomonas vaginalis penicillin-binding protein, putative 0.0023 0.003 0.003
Onchocerca volvulus 0.0018 0.0019 0.0308

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 80 % In vitro agonistic activity of the compound against angiotensin II in the rabbit aorta ChEMBL. 2913307
BP (functional) = 60 mmHg In vivo angiotensin II like activity determined in rat blood pressure assay measured as increase in BP by 1 ug iv of compound ChEMBL. 2913307

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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