Detailed information for compound 546479

Basic information

Technical information
  • TDR Targets ID: 546479
  • Name: 2-(2-naphthyl)ethanol
  • MW: 172.223 | Formula: C12H12O
  • H donors: 1 H acceptors: 1 LogP: 2.75 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCc1ccc2c(c1)cccc2
  • InChi: 1S/C12H12O/c13-8-7-10-5-6-11-3-1-2-4-12(11)9-10/h1-6,9,13H,7-8H2
  • InChiKey: VCZANYLMPFRUHG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(2-naphthalenyl)ethanol
  • 2-naphthalen-2-ylethanol
  • 1-(2-naphthyl)ethanol
  • 1485-07-0
  • ZINC01577328
  • 2-Naphthaleneethanol
  • NSC21040
  • 188107_ALDRICH
  • EINECS 216-061-3
  • Naphthalen-2-ethanol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0043 0.0042 0.0319
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.004 0.0294
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0058 0.0472
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0079
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0028 0.0282
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0028 0.0011 0.0017
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.004 0.026
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0041 0.0065
Trichomonas vaginalis helicase, putative 0.0033 0.0021 0.0136
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0084 0.0133
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0041 0.0065
Mycobacterium ulcerans hypothetical protein 0.045 0.0877 0.8754
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0049 0.0053 0.0053
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0266 0.0499 0.0794
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0266 0.0499 0.0794
Schistosoma mansoni transcription factor LCR-F1 0.0303 0.0576 0.0915
Brugia malayi hypothetical protein 0.0303 0.0576 0.0915
Echinococcus granulosus nuclear receptor nhr 48 0.0047 0.0049 0.0079
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0064 0.0085 0.0134
Plasmodium vivax importin-beta 2, putative 0.0031 0.0017 0.0261
Schistosoma mansoni survival motor neuron protein 0.0151 0.0263 0.0418
Leishmania major glycerol uptake protein, putative 0.0266 0.0499 0.4093
Loa Loa (eye worm) hypothetical protein 0.1532 0.3098 0.4924
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0079
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0266 0.0499 0.7764
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0035 0.0285
Onchocerca volvulus 0.077 0.1533 1
Schistosoma mansoni aldehyde dehydrogenase 0.0028 0.0011 0.0017
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0028 0.0045
Loa Loa (eye worm) hypothetical protein 0.0336 0.0643 0.1022
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0028 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0011
Schistosoma mansoni aldehyde dehydrogenase 0.051 0.1001 0.159
Loa Loa (eye worm) hypothetical protein 0.0053 0.0061 0.0097
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.011 0.0179 0.1465
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0029 0.0237
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0028 0.0011 0.0088
Schistosoma mansoni inositol monophosphatase 0.0037 0.0028 0.0045
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0116 0.0191 0.2082
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0099 0.0157 0.025
Loa Loa (eye worm) hypothetical protein 0.0028 0.0011 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0099 0.0157 0.025
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0035 0.0604
Trypanosoma brucei glycerol uptake protein, putative 0.0266 0.0499 0.4093
Loa Loa (eye worm) hypothetical protein 0.0099 0.0157 0.025
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0043 0.0042 0.0073
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0058 0.0091
Schistosoma mansoni hypothetical protein 0.0046 0.0048 0.0077
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0477 0.0933 0.1483
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0047 0.0049 0.0079
Onchocerca volvulus 0.0043 0.0041 0.0215
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.004 0.026
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0008 0.0013
Schistosoma mansoni hypothetical protein 0.0303 0.0576 0.0915
Echinococcus multilocularis ornithine aminotransferase 0.0064 0.0085 0.0085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0099 0.0157 0.025
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0087 0.0131 0.1076
Loa Loa (eye worm) bromodomain containing protein 0.0026 0.0006 0.0009
Toxoplasma gondii histone lysine methyltransferase SET1 0.0289 0.0547 0.5469
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.0042 0.0348
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0029 0.0189
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0201 0.0365 0.0365
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0477 0.0933 0.0933
Loa Loa (eye worm) hypothetical protein 0.0099 0.0157 0.025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0477 0.0933 0.1483
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0099 0.0157 0.025
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0301 0.057 0.0907
Entamoeba histolytica hypothetical protein 0.0303 0.0576 1
Trypanosoma brucei DNA polymerase eta, putative 0.004 0.0035 0.0285
Echinococcus granulosus fetal alzheimer antigen falz 0.0031 0.0017 0.0028
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0041 0.0816
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0028 0.0011 0.0088
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0035 0.0285
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0266 0.0499 0.867
Entamoeba histolytica hypothetical protein 0.0025 0.0005 0.0083
Trypanosoma cruzi cytochrome P450, putative 0.0063 0.0083 0.0681
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0043 0.0042 0.0319
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0084 0.0133
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0151 0.0263 0.0418
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0028 0.0011 0.0187
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0035 0.0285
Toxoplasma gondii exonuclease III APE 0.0042 0.004 0.0399
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0031 0.0017 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0266 0.0499 0.3257
Loa Loa (eye worm) hypothetical protein 0.0266 0.0499 0.0794
Echinococcus multilocularis FTZ F1 alpha 0.0099 0.0157 0.0157
Loa Loa (eye worm) CYP4Cod1 0.0063 0.0083 0.0132
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0008 0.0013
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0266 0.0499 0.0794
Entamoeba histolytica vacuolar protein sorting 26 0.0266 0.0499 0.867
Brugia malayi hypothetical protein 0.0067 0.009 0.0143
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0028 0.0231
Mycobacterium leprae putative cytochrome p450 0.0043 0.0042 0.0365
Mycobacterium ulcerans acetylornithine aminotransferase 0.0064 0.0085 0.0745
Schistosoma mansoni loxhd1 0.0043 0.0041 0.0065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0099 0.0157 0.025
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0029 0.0289
Brugia malayi hypothetical protein 0.0053 0.0061 0.0097
Loa Loa (eye worm) hypothetical protein 0.004 0.0035 0.0055
Echinococcus granulosus zinc finger protein 0.0036 0.0027 0.0043
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0079
Loa Loa (eye worm) hypothetical protein 0.0053 0.0061 0.0097
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0043 0.0042 0.0319
Brugia malayi Inositol-1 0.0037 0.0028 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0179 0.1166
Brugia malayi follicle stimulating hormone receptor 0.1165 0.2346 0.3728
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0179 0.1465
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0035 0.0285
Brugia malayi ecdysone receptor 0.0047 0.0049 0.0079
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0201 0.0365 0.058
Brugia malayi acetyltransferase, GNAT family protein 0.0316 0.0602 0.0957
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0095 0.0147 0.1474
Schistosoma mansoni lipoxygenase 0.0115 0.019 0.0302
Schistosoma mansoni aldehyde dehydrogenase 0.0028 0.0011 0.0017
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0077 0.0111 0.0111
Echinococcus multilocularis mitogen activated protein kinase 0.011 0.0179 0.0179
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0201 0.0365 0.058
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0266 0.0499 0.867
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0099 0.0157 0.025
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0043 0.0042 0.0319
Toxoplasma gondii LsmAD domain-containing protein 0.0103 0.0165 0.1648
Echinococcus multilocularis GPCR, family 2 0.0095 0.0148 0.0148
Brugia malayi beta-lactamase family protein 0.0336 0.0643 0.1022
Echinococcus granulosus RUN 0.0043 0.0041 0.0065
Onchocerca volvulus 0.0336 0.0643 0.4164
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.0061 0.0097
Schistosoma mansoni nuclear receptor 0.0047 0.0049 0.0079
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.051 0.1001 0.1001
Brugia malayi Steroid receptor seven-up type 2 0.0099 0.0157 0.025
Echinococcus multilocularis cpg binding protein 0.0156 0.0273 0.0273
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0099 0.0157 0.025
Schistosoma mansoni hypothetical protein 0.0331 0.0633 0.1006
Loa Loa (eye worm) hypothetical protein 0.0266 0.0499 0.0794
Trypanosoma brucei hypothetical protein, conserved 0.0336 0.0643 0.5271
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0021 0.0136
Echinococcus granulosus tar DNA binding protein 0.0064 0.0084 0.0133
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0043 0.0042 0.0319
Echinococcus granulosus dnaJ subfamily B 0.125 0.252 0.4005
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.011 0.0179 0.0284
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0266 0.0499 0.0794
Schistosoma mansoni polycystin 1-related 0.0043 0.0041 0.0065
Schistosoma mansoni thyroid hormone receptor 0.0099 0.0157 0.025
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0008 0.0013
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.004 0.0327
Loa Loa (eye worm) hhat protein 0.0266 0.0499 0.0794
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0029 0.0189
Trichomonas vaginalis set domain proteins, putative 0.077 0.1533 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.0148 0.0236
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0029 0.0189
Onchocerca volvulus Huntingtin homolog 0.0378 0.0729 0.473
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1165 0.2346 0.3728
Loa Loa (eye worm) hypothetical protein 0.0336 0.0643 0.1022
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0029 0.0189
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0303 0.0576 0.0915
Trypanosoma brucei glycerol uptake protein, putative 0.0266 0.0499 0.4093
Loa Loa (eye worm) hypothetical protein 0.1532 0.3098 0.4924
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0028 0.0011 0.0088
Echinococcus granulosus thyroid hormone receptor alpha 0.0047 0.0049 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0009 0.0077
Onchocerca volvulus 0.0099 0.0157 0.0979
Echinococcus granulosus Nuclear hormone receptor HR96 0.0047 0.0049 0.0079
Brugia malayi Cytochrome P450 family protein 0.0171 0.0304 0.0483
Loa Loa (eye worm) cytochrome P450 family protein 0.0063 0.0083 0.0132
Echinococcus granulosus FTZ F1 alpha 0.0099 0.0157 0.025
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0047 0.0049 0.0049
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0166 0.0295 0.0468
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0179 0.1166
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0099 0.0157 0.025
Schistosoma mansoni zinc finger protein 0.0036 0.0027 0.0043
Mycobacterium tuberculosis Conserved protein 0.0336 0.0643 0.1453
Echinococcus granulosus o acyltransferase membrane bound domain 0.0266 0.0499 0.0794
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0336 0.0643 0.1022
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0116 0.0191 0.0415
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0477 0.0933 0.1483
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0053 0.0061 0.0061
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0043 0.0042 0.0319
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0079
Onchocerca volvulus 0.0336 0.0643 0.4164
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0079
Mycobacterium ulcerans esterase/lipase LipP 0.0336 0.0643 0.6389
Mycobacterium leprae Probable lipase LipE 0.0336 0.0643 0.7298
Loa Loa (eye worm) hypothetical protein 0.0378 0.0729 0.1159
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0099 0.0157 0.025
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.002 0.011
Entamoeba histolytica hypothetical protein, conserved 0.0266 0.0499 0.867
Brugia malayi hypothetical protein 0.0103 0.0165 0.0262
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0201 0.0365 0.0365
Schistosoma mansoni hypothetical protein 0.0095 0.0148 0.0236
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.051 0.1001 0.8201
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0295 0.0295
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0336 0.0643 0.1022
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0021 0.0136
Entamoeba histolytica hypothetical protein 0.0303 0.0576 1
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0028 0.0011 0.0088
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0028 0.0184
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0043 0.0042 0.0073
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0043 0.0042 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0021 0.0136
Schistosoma mansoni intermediate filament proteins 0.0027 0.0008 0.0013
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.0042 0.0348
Echinococcus multilocularis RUN 0.0043 0.0041 0.0041
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0035 0.0055
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0043 0.0042 0.0319
Schistosoma mansoni ap endonuclease 0.0042 0.004 0.0063
Brugia malayi MBOAT family protein 0.0266 0.0499 0.0794
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0017 0.0138
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.045 0.0877 1
Brugia malayi Importin beta-1 subunit 0.0031 0.0017 0.0027
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0677 0.1342 0.2134
Echinococcus granulosus o acyltransferase membrane bound domain 0.0266 0.0499 0.0794
Loa Loa (eye worm) latrophilin receptor protein 2 0.0095 0.0148 0.0236
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0099 0.0157 0.025
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0035 0.0035
Onchocerca volvulus 0.0047 0.0049 0.0272
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0058 0.0894
Brugia malayi ecdysteroid receptor 0.0099 0.0157 0.025
Plasmodium vivax ornithine aminotransferase, putative 0.0064 0.0085 0.1314
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0053 0.0061 0.0097
Brugia malayi aldehyde dehydrogenase 0.0028 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0336 0.0643 0.1022
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0028 0.0011 0.0011
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0099 0.0157 0.025
Echinococcus granulosus zinc finger protein 0.2822 0.5745 0.9132
Brugia malayi nuclear hormone receptor family member odr-7 0.0047 0.0049 0.0079
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0047 0.0049 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0099 0.0157 0.025
Echinococcus multilocularis musashi 0.0027 0.0008 0.0008
Echinococcus multilocularis sterol O acyltransferase 1 0.0266 0.0499 0.0499
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0035 0.0055
Loa Loa (eye worm) MBOAT family protein 0.3088 0.6291 1
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0029 0.0189
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0028 0.0011 0.0108
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0266 0.0499 0.0499
Brugia malayi nuclear hormone receptor family member nhr-6 0.0047 0.0049 0.0079
Trichomonas vaginalis penicillin-binding protein, putative 0.0336 0.0643 0.4195
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0316 0.0602 0.0957
Brugia malayi Bromodomain containing protein 0.0093 0.0143 0.0228
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0028 0.0011 0.0019
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0331 0.0633 0.1006
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0028 0.0176
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.0165 0.1352
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0029 0.0503
Entamoeba histolytica hypothetical protein 0.0303 0.0576 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0201 0.0365 1
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0028 0.0045
Plasmodium falciparum thioredoxin reductase 0.0051 0.0058 0.1152
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0043 0.0042 0.0348
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0201 0.0365 0.058
Brugia malayi beta-lactamase family protein 0.0336 0.0643 0.1022
Loa Loa (eye worm) hypothetical protein 0.0099 0.0157 0.025
Plasmodium vivax SET domain protein, putative 0.01 0.0158 0.2457
Loa Loa (eye worm) hypothetical protein 0.0099 0.0157 0.025
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0099 0.0157 0.025
Onchocerca volvulus 0.02 0.0364 0.2337
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0017 0.0017
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0099 0.0157 0.025
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0064 0.0085 0.0169
Echinococcus granulosus dna polymerase kappa 0.004 0.0035 0.0055
Toxoplasma gondii hypothetical protein 0.01 0.0157 0.1574
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0099 0.0157 0.0979
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0336 0.0643 0.6389
Brugia malayi PHD-finger family protein 0.0041 0.0038 0.0061
Leishmania major hypothetical protein, conserved 0.0336 0.0643 0.5271
Mycobacterium tuberculosis Conserved protein 0.0336 0.0643 0.1453
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0005 0.0039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0117 0.0194 0.0308
Loa Loa (eye worm) hypothetical protein 0.0336 0.0643 0.1022
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0336 0.0643 0.1453
Echinococcus granulosus mitogen activated protein kinase 0.011 0.0179 0.0284
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0047 0.0049 0.0079
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0095 0.0147 0.0962
Echinococcus multilocularis muscleblind protein 0.1532 0.3098 0.3098
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0079
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0064 0.0085 0.0745
Echinococcus granulosus lysosomal alpha glucosidase 0.0166 0.0295 0.0468
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.0165 0.1352
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.045 0.0877 0.1992
Brugia malayi nuclear receptor RXR 0.0047 0.0049 0.0079
Brugia malayi MBOAT family protein 0.0266 0.0499 0.0794
Onchocerca volvulus Bile acid receptor homolog 0.0099 0.0157 0.0979
Echinococcus granulosus histone acetyltransferase KAT2B 0.0095 0.0147 0.0234
Schistosoma mansoni zinc finger protein 0.0047 0.0049 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0035 0.0285
Echinococcus multilocularis zinc finger protein 0.2822 0.5745 0.5745
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0028 0.0011 0.0187
Loa Loa (eye worm) steroid hormone receptor 0.0099 0.0157 0.025
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0028 0.0184
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0266 0.0499 0.0794
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0064 0.0085 0.0169
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0043 0.0042 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0266 0.0499 0.3257
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0035 0.0055
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.004 0.0621
Loa Loa (eye worm) hypothetical protein 0.0099 0.0157 0.025
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0336 0.0643 0.1022
Echinococcus granulosus sterol O acyltransferase 1 0.0266 0.0499 0.0794
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0017 0.0138
Mycobacterium tuberculosis Probable hydrolase 0.0336 0.0643 0.1453
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0013
Mycobacterium ulcerans aldehyde dehydrogenase 0.051 0.1001 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0005 0.0031
Brugia malayi photoreceptor-specific nuclear receptor 0.0099 0.0157 0.025
Trichomonas vaginalis porcupine, putative 0.0266 0.0499 0.3257
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0043 0.0042 0.0319
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0028 0.0011 0.0108
Brugia malayi Doublecortin family protein 0.0043 0.0041 0.0065
Trypanosoma brucei PAB1-binding protein , putative 0.0103 0.0165 0.1352
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.045 0.0877 0.8754
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0617 0.122 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0192 0.0348 0.0348
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0049 0.0079
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0266 0.0499 0.0794
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0116 0.0191 0.0415
Onchocerca volvulus Protein ultraspiracle homolog 0.0099 0.0157 0.0979
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0043 0.0042 0.0319
Echinococcus granulosus mitogen activated protein kinase 3 0.011 0.0179 0.0284
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0043 0.0042 0.0073
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0292 0.0553 0.453
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0158 0.0251
Echinococcus multilocularis beta LACTamase domain containing family member 0.0336 0.0643 0.0643
Brugia malayi F/Y-rich N-terminus family protein 0.005 0.0056 0.0089
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.0058 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0021 0.0136
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0031 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0028 0.0011 0.0017
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0028 0.0231
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0028 0.0011 0.0088
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0035 0.0035
Trypanosoma cruzi glycerol uptake protein, putative 0.0266 0.0499 0.4093
Schistosoma mansoni sterol O-acyltransferase 1 0.0266 0.0499 0.0794
Echinococcus granulosus importin subunit beta 1 0.0031 0.0017 0.0027
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0048 0.0048
Brugia malayi conserved hypotetical protein 0.0047 0.0049 0.0079
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0028 0.2362
Echinococcus multilocularis dnaJ subfamily B 0.125 0.252 0.252
Giardia lamblia Histone acetyltransferase GCN5 0.0085 0.0127 0.3474
Loa Loa (eye worm) hypothetical protein 0.0266 0.0499 0.0794
Brugia malayi MAP kinase sur-1 0.011 0.0179 0.0284
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0043 0.0042 0.0073
Trypanosoma brucei protein kinase, putative 0.011 0.0179 0.1465
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0043 0.0042 0.0073
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0035 0.0285
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0301 0.057 0.0907
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0043 0.0042 0.0073
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0041 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0201 0.0365 0.2379
Schistosoma mansoni nuclear receptor 0.0047 0.0049 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0021 0.0136
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0477 0.0933 0.1483
Brugia malayi Thioredoxin reductase 0.0051 0.0058 0.0091
Brugia malayi tailless protein 0.0047 0.0049 0.0079
Plasmodium vivax hypothetical protein, conserved 0.0336 0.0643 1
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0028 0.0011 0.0017
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0028 0.0231
Brugia malayi MH2 domain containing protein 0.0122 0.0203 0.0323
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0035 0.0055
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0047 0.0049 0.0272
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0029 0.0503
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0099 0.0157 0.025
Schistosoma mansoni lamin 0.0027 0.0008 0.0013
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0029 0.0029
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0063 0.0083 0.0731
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0035 0.0285
Schistosoma mansoni cellular tumor antigen P53 0.02 0.0364 0.0579
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0099 0.0157 0.0157
Schistosoma mansoni nuclear hormone receptor 0.0099 0.0157 0.025
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0043 0.0042 0.0073
Loa Loa (eye worm) hypothetical protein 0.0053 0.0061 0.0097
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0095 0.0147 0.1474
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0035 0.0285
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0084 0.0133
Echinococcus granulosus cytochrome P450 2K1 0.0043 0.0042 0.0067
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.004 0.0063
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0043 0.0042 0.0348
Onchocerca volvulus 0.0266 0.0499 0.3221
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0028 0.0011 0.0088
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0035 0.0055
Schistosoma mansoni cpg binding protein 0.0146 0.0252 0.04
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0017 0.0168
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0029 0.0237
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0116 0.0191 0.0415
Schistosoma mansoni alpha-glucosidase 0.0143 0.0247 0.0393
Loa Loa (eye worm) MBOAT family protein 0.0266 0.0499 0.0794
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0266 0.0499 0.0499
Plasmodium vivax ataxin-2 like protein, putative 0.0103 0.0165 0.2564
Echinococcus multilocularis zinc finger protein 0.0036 0.0027 0.0027
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0061 0.0097
Schistosoma mansoni eyes absent homolog 0.0097 0.0153 0.0243
Toxoplasma gondii aldehyde dehydrogenase 0.051 0.1001 1
Echinococcus multilocularis lamin 0.0027 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0099 0.0157 0.025
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0064 0.0085 0.0745
Schistosoma mansoni alpha-glucosidase 0.0143 0.0247 0.0393
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0266 0.0499 0.0499
Schistosoma mansoni hypothetical protein 0.0095 0.0148 0.0236
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0041 0.0065
Loa Loa (eye worm) hypothetical protein 0.0049 0.0054 0.0086
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.0165 0.3303
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0028 0.0011 0.0088
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0028 0.0011 0.0108
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0049 0.0079
Echinococcus granulosus cpg binding protein 0.0156 0.0273 0.0434
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0043 0.0042 0.0319
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0028 0.0011 0.0011
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.01 0.0158 0.0158
Echinococcus multilocularis muscleblind protein 1 0.1532 0.3098 0.3098
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0266 0.0499 0.0794
Brugia malayi Aldehyde dehydrogenase protein 4 0.0028 0.0011 0.0017
Schistosoma mansoni cpg binding protein 0.0156 0.0273 0.0434
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.011 0.0179 0.1787
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0266 0.0499 0.0794
Leishmania major glycerol uptake protein, putative 0.0266 0.0499 0.4093
Brugia malayi nuclear hormone receptor 0.0099 0.0157 0.025
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.004 0.0063
Onchocerca volvulus Huntingtin homolog 0.0378 0.0729 0.473
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0079
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0312 0.0594 0.0944
Loa Loa (eye worm) aldehyde dehydrogenase 0.0028 0.0011 0.0017
Mycobacterium tuberculosis Probable lipase LipE 0.0336 0.0643 0.1453
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0028 0.0011 0.0088
Echinococcus multilocularis lamin dm0 0.0027 0.0008 0.0008
Mycobacterium ulcerans hypothetical protein 0.0336 0.0643 0.6389
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.004 0.1094
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0035 0.0055
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0087 0.0131 0.1076
Schistosoma mansoni rab6-interacting 0.0043 0.0041 0.0065
Loa Loa (eye worm) hypothetical protein 0.0097 0.0153 0.0243
Giardia lamblia Alcohol dehydrogenase 0.0028 0.0011 0.0296
Mycobacterium tuberculosis Conserved protein 0.0336 0.0643 0.1453
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0005 0.0031
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0617 0.122 1
Loa Loa (eye worm) RNA binding protein 0.0064 0.0084 0.0133
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0316 0.0602 0.0602
Toxoplasma gondii hypothetical protein 0.0266 0.0499 0.4991
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0084 0.0133
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0047 0.0049 0.0049
Mycobacterium ulcerans hypothetical protein 0.0325 0.062 0.616
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0087 0.0131 0.1076
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0043 0.0042 0.0073
Leishmania major cytochrome p450-like protein 0.0043 0.0042 0.0348
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0292 0.0553 0.453
Trypanosoma brucei cytochrome P450, putative 0.0063 0.0083 0.0681
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.004 0.0327
Schistosoma mansoni hypothetical protein 0.0043 0.0041 0.0065
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0049 0.0079
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.002 0.0022
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0129 0.0218 0.2389
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0028 0.0011 0.0108
Schistosoma mansoni bromodomain containing protein 0.0081 0.0119 0.0189
Brugia malayi Muscleblind-like protein 0.1532 0.3098 0.4924
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0035 0.0285
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0117 0.0194 0.0194
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0201 0.0365 0.299
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0095 0.0148 0.0236
Plasmodium falciparum importin beta, putative 0.0031 0.0017 0.0337
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.011 0.0179 0.1465
Loa Loa (eye worm) hypothetical protein 0.0099 0.0157 0.025
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0049 0.0053 0.0084
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0201 0.0365 0.299
Mycobacterium ulcerans aldehyde dehydrogenase 0.051 0.1001 1
Echinococcus granulosus o acyltransferase membrane bound domain 0.0266 0.0499 0.0794
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0043 0.0042 0.0073
Loa Loa (eye worm) hypothetical protein 0.0266 0.0499 0.0794
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0035 0.0285
Brugia malayi Calcitonin receptor-like protein seb-1 0.0301 0.057 0.0907
Loa Loa (eye worm) hypothetical protein 0.0053 0.0061 0.0097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0099 0.0157 0.025
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0028 0.0011 0.0187
Trypanosoma brucei unspecified product 0.0027 0.0009 0.0077
Schistosoma mansoni hypothetical protein 0.0206 0.0375 0.0596
Loa Loa (eye worm) glutathione reductase 0.0051 0.0058 0.0091
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0028 0.0028
Schistosoma mansoni alpha glucosidase 0.0037 0.0029 0.0046
Loa Loa (eye worm) acetyltransferase 0.0316 0.0602 0.0957
Echinococcus granulosus intermediate filament protein 0.0027 0.0008 0.0013
Loa Loa (eye worm) MBOAT family protein 0.0266 0.0499 0.0794
Leishmania major cytochrome p450-like protein 0.0063 0.0083 0.0681
Schistosoma mansoni hypothetical protein 0.0095 0.0148 0.0236
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0064 0.0085 0.5
Leishmania major DNA polymerase eta, putative 0.004 0.0035 0.0285
Onchocerca volvulus 0.0146 0.0252 0.1599
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0021 0.0136
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.3088 0.6291 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0116 0.0191 0.0415
Loa Loa (eye worm) CXXC zinc finger family protein 0.0146 0.0252 0.04
Schistosoma mansoni aldehyde dehydrogenase 0.051 0.1001 0.159
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0021 0.0136
Echinococcus granulosus tumor protein p63 0.1369 0.2763 0.4392
Mycobacterium leprae conserved hypothetical protein 0.0336 0.0643 0.7298
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0095 0.0148 0.0236
Mycobacterium tuberculosis Possible penicillin-binding protein 0.2147 0.4361 1
Schistosoma mansoni DNA polymerase eta 0.004 0.0035 0.0055
Brugia malayi Hhat protein 0.0266 0.0499 0.0794
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0099 0.0157 0.025
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0064 0.0085 0.0745
Onchocerca volvulus 0.0096 0.0151 0.0936
Loa Loa (eye worm) cytochrome P450 0.0043 0.0042 0.0067
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0079
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0477 0.0933 0.1483
Leishmania major trypanothione reductase 0.0051 0.0058 0.0472
Loa Loa (eye worm) hhat protein 0.0266 0.0499 0.0794
Schistosoma mansoni coup transcription factor 0.0099 0.0157 0.025
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0028 0.0011 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0009 0.0077
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0064 0.0085 0.0134
Echinococcus granulosus snurportin 1 0.0331 0.0633 0.1006
Trichomonas vaginalis transmembrane protein nessy, putative 0.0266 0.0499 0.3257
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0266 0.0499 0.0794
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0266 0.0499 0.4991
Loa Loa (eye worm) hypothetical protein 0.0117 0.0194 0.0308
Brugia malayi steroid hormone receptor 0.0099 0.0157 0.025
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0028 0.0011 0.0088
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.0203 0.0323
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0064 0.0085 0.0745
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0266 0.0499 0.0794
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0028 0.0011 0.0088
Brugia malayi TAR-binding protein 0.0064 0.0084 0.0133
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0043 0.0042 0.0073
Brugia malayi Pre-SET motif family protein 0.0677 0.1342 0.2134
Brugia malayi RNA, U transporter 1 0.0088 0.0134 0.0213
Giardia lamblia Kinase, CMGC MAPK 0.011 0.0179 0.49
Brugia malayi Cytochrome P450 family protein 0.0063 0.0083 0.0132
Trypanosoma cruzi DNA polymerase eta, putative 0.004 0.0035 0.0285
Brugia malayi orphan nuclear receptor NR2E1 0.0047 0.0049 0.0079
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0035 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0043 0.0042 0.0073
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0029 0.0189
Onchocerca volvulus 0.0151 0.0263 0.1673
Loa Loa (eye worm) inositol-1 0.0037 0.0028 0.0045
Mycobacterium ulcerans L-lysine aminotransferase 0.0064 0.0085 0.0745
Loa Loa (eye worm) DR-78 0.0047 0.0049 0.0079
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0029 0.0237
Schistosoma mansoni lipoxygenase 0.0192 0.0348 0.0553
Schistosoma mansoni aldehyde dehydrogenase 0.0028 0.0011 0.0017
Echinococcus granulosus mixed lineage leukemia protein mll 0.004 0.0035 0.0055
Schistosoma mansoni importin beta-1 0.0031 0.0017 0.0027
Trypanosoma cruzi glycerol uptake protein, putative 0.0266 0.0499 0.4093
Brugia malayi Cytochrome P450 family protein 0.0043 0.0042 0.0067
Plasmodium falciparum ornithine aminotransferase 0.0064 0.0085 0.1693
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.004 0.0327
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0099 0.0157 0.025
Brugia malayi Cytochrome P450 family protein 0.0063 0.0083 0.0132
Echinococcus multilocularis mixed lineage leukemia protein mll 0.004 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0079
Trypanosoma brucei glucosidase, putative 0.0037 0.0029 0.0237
Brugia malayi nuclear receptor NHR-67 0.0047 0.0049 0.0079
Leishmania major DNA polymerase kappa, putative 0.004 0.0035 0.0285
Schistosoma mansoni rab6-interacting 0.0043 0.0041 0.0065
Toxoplasma gondii cytochrome p450 superfamily protein 0.0043 0.0042 0.0424
Loa Loa (eye worm) hypothetical protein 0.0043 0.0041 0.0065
Loa Loa (eye worm) histone methyltransferase 0.0049 0.0053 0.0084
Loa Loa (eye worm) hypothetical protein 0.006 0.0075 0.012
Schistosoma mansoni steroid hormone receptor ad4bp 0.0099 0.0157 0.025
Schistosoma mansoni thyroid hormone receptor 0.0099 0.0157 0.025
Trichomonas vaginalis esterase, putative 0.0336 0.0643 0.4195
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0029 0.0046
Brugia malayi hypothetical protein 0.0047 0.0049 0.0079
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0095 0.0148 0.0236
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0029 0.0046
Trypanosoma cruzi cytochrome P450, putative 0.0063 0.0083 0.0681
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.004 0.0799
Onchocerca volvulus 0.0047 0.0049 0.0272
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0047 0.0049 0.0079
Leishmania major hypothetical protein, conserved 0.0103 0.0165 0.1352
Schistosoma mansoni lamin 0.0027 0.0008 0.0013
Echinococcus multilocularis dna polymerase kappa 0.004 0.0035 0.0035
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0099 0.0157 0.0157
Loa Loa (eye worm) cytochrome P450 family protein 0.0171 0.0304 0.0483
Schistosoma mansoni hypothetical protein 0.0266 0.0499 0.0794
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0095 0.0147 0.2293
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0043 0.0042 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0021 0.0136
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0617 0.122 1
Leishmania major aldehyde dehydrogenase, putative 0.0028 0.0011 0.0088
Giardia lamblia DINP protein human, muc B family 0.004 0.0035 0.0953
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.011 0.0179 0.1465
Leishmania major hypothetical protein, conserved 0.0266 0.0499 0.4093
Mycobacterium ulcerans lipase LipD 0.0336 0.0643 0.6389
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0336 0.0643 0.1453
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0043 0.0042 0.0073
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0021 0.0136
Loa Loa (eye worm) hypothetical protein 0.0097 0.0153 0.0243
Loa Loa (eye worm) hypothetical protein 0.0039 0.0034 0.0053
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0099 0.0157 0.025
Loa Loa (eye worm) hypothetical protein 0.0103 0.0165 0.0262
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0079
Echinococcus granulosus neuropeptide s receptor 0.0998 0.2002 0.3183
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0099 0.0157 0.025
Schistosoma mansoni nuclear receptor nhr-48 0.0047 0.0049 0.0079
Toxoplasma gondii thioredoxin reductase 0.0051 0.0058 0.0575
Schistosoma mansoni aldehyde dehydrogenase 0.0028 0.0011 0.0017
Schistosoma mansoni retinoic acid receptor RXR 0.0099 0.0157 0.025
Brugia malayi beta-lactamase 0.0336 0.0643 0.1022
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0028 0.0011 0.0017
Trypanosoma brucei trypanothione reductase 0.0051 0.0058 0.0472
Echinococcus granulosus Nuclear hormone receptor HR96 0.0047 0.0049 0.0079
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0041 0.0065
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0053 0.0061 0.0097
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0035 0.0055
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0099 0.0157 0.025
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0043 0.0042 0.0073
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0028 0.0011 0.0017
Echinococcus granulosus ecdysone induced protein 78C 0.0099 0.0157 0.025
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0064 0.0085 0.0851
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0021 0.0136
Brugia malayi MBOAT family protein 0.0266 0.0499 0.0794
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0079
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0043 0.0042 0.0348
Echinococcus multilocularis neuropeptide s receptor 0.0998 0.2002 0.2002
Leishmania major cytochrome p450-like protein 0.0043 0.0042 0.0348
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0035 0.0285
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0079
Brugia malayi intermediate filament protein 0.0027 0.0008 0.0013
Schistosoma mansoni inositol monophosphatase 0.0037 0.0028 0.0045
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0021 0.0136
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0064 0.0085 0.0169
Echinococcus granulosus muscleblind protein 0.1532 0.3098 0.4924
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0099 0.0157 0.025
Brugia malayi hypothetical protein 0.0043 0.0041 0.0065
Echinococcus multilocularis nuclear receptor nhr 48 0.0047 0.0049 0.0049
Brugia malayi Bromodomain containing protein 0.0047 0.0049 0.0078
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0064 0.0085 0.0851
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0028 0.0011 0.007
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0099 0.0157 0.0157
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0292 0.0553 0.453
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0099 0.0157 0.0157
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0028 0.0011 0.0088
Schistosoma mansoni aldehyde dehydrogenase 0.0028 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0336 0.0643 0.1022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0017 0.0027
Schistosoma mansoni hypothetical protein 0.0151 0.0263 0.0418
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0043 0.0042 0.0319
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0028 0.0011 0.0088
Mycobacterium tuberculosis Conserved hypothetical protein 0.0325 0.062 0.1401
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0053 0.0061 0.0097
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.01 0.0158 0.1579
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0043 0.0042 0.0319
Trypanosoma brucei unspecified product 0.004 0.0035 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0021 0.0136
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.3088 0.6291 0.6291
Trichomonas vaginalis D-aminoacylase, putative 0.0336 0.0643 0.4195
Mycobacterium leprae Conserved hypothetical protein 0.0043 0.0042 0.0365
Onchocerca volvulus 0.0336 0.0643 0.4164
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0047 0.0049 0.0049
Schistosoma mansoni zinc finger protein 0.3088 0.6291 1
Leishmania major mitochondrial DNA polymerase beta 0.0617 0.122 1
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0035 0.0242
Mycobacterium tuberculosis Probable oxidoreductase 0.0129 0.0218 0.0476
Trichomonas vaginalis bromodomain-containing protein, putative 0.0095 0.0147 0.0962
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.004 0.0596
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0043 0.0042 0.0073
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0028 0.0011 0.0017
Echinococcus multilocularis snurportin 1 0.0331 0.0633 0.0633
Entamoeba histolytica acetyltransferase, GNAT family 0.0085 0.0127 0.2201
Brugia malayi hypothetical protein 0.0043 0.0041 0.0065
Schistosoma mansoni hypothetical protein 0.0043 0.0042 0.0067
Echinococcus multilocularis geminin 0.0165 0.0291 0.0291
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0093 0.0144 0.0229
Trypanosoma brucei unspecified product 0.0027 0.0009 0.0077
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0029 0.0189
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0043 0.0042 0.0073
Leishmania major glycerol uptake protein, putative 0.0266 0.0499 0.4093
Echinococcus granulosus lamin 0.0027 0.0008 0.0013
Brugia malayi nuclear receptor RXR 0.0053 0.0061 0.0097
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0021 0.0136
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0201 0.0365 0.058
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0084 0.0133
Schistosoma mansoni ap endonuclease 0.0042 0.004 0.0063
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0303 0.0576 0.0576
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0028 0.0011 0.0011
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0035 0.0055
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0029 0.0046
Echinococcus granulosus histone lysine methyltransferase setb 0.0117 0.0194 0.0308
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0028 0.049
Echinococcus multilocularis ornithine aminotransferase 0.0064 0.0085 0.0085
Brugia malayi Latrophilin receptor protein 2 0.0095 0.0148 0.0236
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0058 0.0091
Trypanosoma cruzi GUP1, putative 0.0266 0.0499 0.4093
Schistosoma mansoni mixed-lineage leukemia protein mll 0.004 0.0035 0.0055
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0043 0.0042 0.0319
Echinococcus multilocularis ubiquitin specific protease 41 0.0201 0.0365 0.0365
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.051 0.1001 0.2275
Echinococcus multilocularis 0.0043 0.0042 0.0042
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0035 0.0285
Brugia malayi nuclear receptor NHR-88 0.0099 0.0157 0.025
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0043 0.0042 0.0073
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0028 0.0011 0.0011
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0266 0.0499 0.0794
Trichomonas vaginalis D-aminoacylase, putative 0.0336 0.0643 0.4195
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0477 0.0933 0.1483
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0064 0.0085 0.0169
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0116 0.0191 0.0415
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0021 0.0136
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0035 0.0285
Toxoplasma gondii ABC1 family protein 0.0336 0.0643 0.6428
Echinococcus multilocularis microtubule associated protein 2 0.1483 0.2998 0.2998
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.051 0.1001 0.159
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0266 0.0499 0.0499
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0192 0.0348 0.0553
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0179 0.1166
Schistosoma mansoni hypothetical protein 0.125 0.252 0.4005
Mycobacterium tuberculosis Probable aminotransferase 0.045 0.0877 0.1992
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.0203 0.0323
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0179 0.1166
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.01 0.0158 0.0251
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0095 0.0148 0.0148
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0035 0.0242
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0266 0.0499 1
Brugia malayi nuclear receptor NHR-88 0.0047 0.0049 0.0079
Onchocerca volvulus 0.01 0.0158 0.0984
Echinococcus multilocularis thyroid hormone receptor alpha 0.0099 0.0157 0.0157
Mycobacterium ulcerans beta-lactamase 0.0336 0.0643 0.6389
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0099 0.0157 0.025
Schistosoma mansoni microtubule-associated protein tau 0.1483 0.2998 0.4765
Loa Loa (eye worm) hypothetical protein 0.0053 0.0061 0.0097
Loa Loa (eye worm) cytochrome P450 family protein 0.0063 0.0083 0.0132
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0028 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0043 0.0042 0.0073
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0179 0.1465
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0028 0.0011 0.0187
Loa Loa (eye worm) hypothetical protein 0.0099 0.0157 0.025
Echinococcus multilocularis Aminotransferase class III 0.0064 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.0165 0.0291 0.0463
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0201 0.0365 0.058
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0043 0.0042 0.0319
Leishmania major glycerol uptake protein, putative 0.0266 0.0499 0.4093
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.011 0.0179 0.1465
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0477 0.0933 0.0933
Schistosoma mansoni cytochrome P450 0.0043 0.0042 0.0067
Loa Loa (eye worm) hypothetical protein 0.0336 0.0643 0.1022
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0179 0.0284
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0087 0.0131 0.1076
Trichomonas vaginalis D-aminoacylase, putative 0.0336 0.0643 0.4195
Brugia malayi hypothetical protein 0.0053 0.0061 0.0097
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0028 0.0011 0.0088
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0005 0.0031
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0266 0.0499 0.0499
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0099 0.0157 0.025
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.004 0.0327
Echinococcus granulosus ubiquitin specific protease 41 0.0201 0.0365 0.058
Brugia malayi CXXC zinc finger family protein 0.0146 0.0252 0.04
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0336 0.0643 0.1453
Plasmodium falciparum histone acetyltransferase GCN5 0.0085 0.0127 0.2538
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0028 0.0184
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0099 0.0157 0.025
Trypanosoma cruzi hypothetical protein, conserved 0.0336 0.0643 0.5271
Brugia malayi RNA binding protein 0.0064 0.0084 0.0133
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0129 0.0218 0.0476
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0035 0.0285
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0035 0.0285
Brugia malayi Nuclear hormone receptor E75 0.0047 0.0049 0.0079
Schistosoma mansoni hypothetical protein 0.0028 0.0011 0.0017
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0047 0.0049 0.0079
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0099 0.0157 0.025
Trypanosoma cruzi glycerol uptake protein, putative 0.0266 0.0499 0.4093
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0035 0.0285
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0009 0.0077
Brugia malayi hypothetical protein 0.0097 0.0153 0.0243
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0201 0.0365 0.2379
Brugia malayi Nuclear hormone receptor-like 1 0.0099 0.0157 0.025
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.0165 0.3303
Plasmodium falciparum glutathione reductase 0.0051 0.0058 0.1152
Brugia malayi latrophilin 2 splice variant baaae 0.0206 0.0375 0.0596
Schistosoma mansoni cpg binding protein 0.0156 0.0273 0.0434
Treponema pallidum alginate O-acetylation protein (algI) 0.0266 0.0499 1
Echinococcus multilocularis dna polymerase eta 0.004 0.0035 0.0035
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0021 0.0136
Mycobacterium tuberculosis Probable lipase LipD 0.0336 0.0643 0.1453
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0099 0.0157 0.025
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0028 0.0231
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0201 0.0365 0.6334
Mycobacterium tuberculosis Probable esterase LipL 0.0336 0.0643 0.1453
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0042 0.004 0.3949
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0043 0.0042 0.0319
Echinococcus granulosus neuropeptide receptor A26 0.0998 0.2002 0.3183
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0043 0.0042 0.0073
Leishmania major aldehyde dehydrogenase, putative 0.0028 0.0011 0.0088
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0295 0.0295
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0129 0.0218 0.0476
Trichomonas vaginalis penicillin-binding protein, putative 0.0336 0.0643 0.4195
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0028 0.0011 0.0011
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0099 0.0157 0.025
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0099 0.0157 0.025
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0099 0.0157 0.025
Mycobacterium ulcerans aldehyde dehydrogenase 0.051 0.1001 1
Leishmania major aldehyde dehydrogenase, putative 0.0028 0.0011 0.0088
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0099 0.0157 0.0157
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.004 0.0063
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0048 0.0077
Brugia malayi Pre-SET motif family protein 0.01 0.0158 0.0251
Brugia malayi nuclear hormone receptor 0.0047 0.0049 0.0079
Brugia malayi Glycosyl hydrolases family 31 protein 0.0166 0.0295 0.0468
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0003 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0266 0.0499 0.3257
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0043 0.0042 0.0073
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0028 0.0011 0.0088
Brugia malayi hypothetical protein 0.0378 0.0729 0.1159
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0336 0.0643 0.1022
Brugia malayi MBOAT family protein 0.0266 0.0499 0.0794
Leishmania major glycerol uptake protein, putative 0.0266 0.0499 0.4093
Brugia malayi Nuclear hormone receptor E75 0.0047 0.0049 0.0079
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0028 0.0011 0.0017
Echinococcus granulosus dna polymerase eta 0.004 0.0035 0.0055
Echinococcus multilocularis survival motor neuron protein 1 0.074 0.1473 0.1473
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0095 0.0148 0.0148
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0043 0.0042 0.0319
Echinococcus granulosus Aminotransferase class III 0.0064 0.0085 0.0134
Schistosoma mansoni RAR-like nuclear receptor 0.0099 0.0157 0.025
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0035 0.0227
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0201 0.0365 0.2379
Echinococcus multilocularis ecdysone induced protein 78C 0.0099 0.0157 0.0157
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0064 0.0085 0.0851
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0084 0.0133
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0266 0.0499 0.0794
Loa Loa (eye worm) beta-lactamase 0.0336 0.0643 0.1022
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0378 0.0729 0.1159
Trypanosoma cruzi hypothetical protein, conserved 0.0336 0.0643 0.5271
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0028 0.0011 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0021 0.0136
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0061 0.0097
Brugia malayi hypothetical protein 0.0047 0.0049 0.0079
Echinococcus granulosus lamin dm0 0.0027 0.0008 0.0013
Brugia malayi MBOAT family protein 0.3088 0.6291 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0041 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0117 0.0194 0.0308
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0043 0.0042 0.0319
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0043 0.0042 0.0073
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0028 0.0011 0.0088
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0201 0.0365 0.299
Brugia malayi hypothetical protein 0.074 0.1473 0.2341
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0084 0.0084
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0266 0.0499 0.0499
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0035 0.0227
Echinococcus multilocularis tumor protein p63 0.1369 0.2763 0.2763
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0099 0.0157 0.025
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0047 0.0049 0.0272
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0084 0.0133
Leishmania major importin beta-1 subunit, putative 0.0025 0.0005 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0099 0.0157 0.025
Echinococcus granulosus GPCR family 2 0.0095 0.0148 0.0236
Onchocerca volvulus 0.0043 0.0041 0.0215
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0266 0.0499 0.867
Echinococcus granulosus histone acetyltransferase KAT2B 0.0305 0.0579 0.092
Echinococcus granulosus microtubule associated protein 2 0.1483 0.2998 0.4765
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0035 0.0285
Schistosoma mansoni hypothetical protein 0.0095 0.0148 0.0236
Loa Loa (eye worm) hypothetical protein 0.0301 0.057 0.0907
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0099 0.0157 0.025
Brugia malayi glutathione reductase 0.0051 0.0058 0.0091
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0028 0.0011 0.0017
Loa Loa (eye worm) nuclear hormone receptor 0.0047 0.0049 0.0079
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0201 0.0365 0.299
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0041 0.0634
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0029 0.0189
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.045 0.0877 0.5721
Loa Loa (eye worm) nuclear receptor NHR-67 0.0047 0.0049 0.0079
Echinococcus granulosus ornithine aminotransferase 0.0064 0.0085 0.0134
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0028 0.0011 0.0017
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0084 0.0133
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0035 0.0285
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0028 0.0011 0.0088
Mycobacterium tuberculosis Probable reductase 0.0116 0.0191 0.0415
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0064 0.0085 1
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0064 0.0085 0.0845
Entamoeba histolytica hypothetical protein 0.0303 0.0576 1
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0028 0.0011 0.0088
Echinococcus granulosus survival motor neuron protein 1 0.074 0.1473 0.2341
Loa Loa (eye worm) hypothetical protein 0.074 0.1473 0.2341
Loa Loa (eye worm) hypothetical protein 0.0072 0.0101 0.0161
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0029 0.0189
Loa Loa (eye worm) hypothetical protein 0.0201 0.0365 0.058
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0077 0.0111 0.0177
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0049 0.0049
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.004 0.0693
Loa Loa (eye worm) hypothetical protein 0.0206 0.0375 0.0596
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0477 0.0933 0.1483
Echinococcus granulosus geminin 0.0165 0.0291 0.0463
Plasmodium vivax glutathione reductase, putative 0.0051 0.0058 0.0894
Brugia malayi diacylglycerol acyltransferase 0.0266 0.0499 0.0794
Trypanosoma cruzi GUP1, putative 0.0266 0.0499 0.4093
Brugia malayi cytochrome P450 0.0043 0.0042 0.0067
Loa Loa (eye worm) hypothetical protein 0.0043 0.0041 0.0065
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0106 0.017 0.1396
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0266 0.0499 0.4991
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0099 0.0157 0.0157
Entamoeba histolytica hypothetical protein 0.0266 0.0499 0.867
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.011 0.0179 0.1465
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0079
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0047 0.0049 0.0049
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0266 0.0499 0.0499
Loa Loa (eye worm) hypothetical protein 0.02 0.0364 0.0579
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.004 0.0067
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0028 0.0011 0.0017
Echinococcus granulosus beta LACTamase domain containing family member 0.0336 0.0643 0.1022
Schistosoma mansoni hypothetical protein 0.0165 0.0291 0.0463
Echinococcus multilocularis neuropeptide receptor A26 0.0998 0.2002 0.2002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0021 0.0136
Echinococcus multilocularis mitogen activated protein kinase 3 0.011 0.0179 0.0179

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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