Detailed information for compound 104546

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 327.376 | Formula: C22H17NO2
  • H donors: 1 H acceptors: 2 LogP: 5.2 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#C/C(=C(\c1ccc(cc1)O)/c1ccc(cc1)OC)/c1ccccc1
  • InChi: 1S/C22H17NO2/c1-25-20-13-9-18(10-14-20)22(17-7-11-19(24)12-8-17)21(15-23)16-5-3-2-4-6-16/h2-14,24H,1H3/b22-21-
  • InChiKey: SLEVTFRYAPIPJW-DQRAZIAOSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0017 0.0015
Onchocerca volvulus Huntingtin homolog 0.013 0.0273 0.027
Schistosoma mansoni hypothetical protein 0.028 0.0628 0.0625
Loa Loa (eye worm) hypothetical protein 0.0719 0.1669 0.1668
Echinococcus granulosus roundabout 2 0.0104 0.0211 0.0208
Echinococcus granulosus transient receptor potential ion channel A 0.02 0.0439 0.0436
Entamoeba histolytica tyrosin kinase, putative 0.0016 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0058 0.0103 0.0101
Leishmania major GTP-binding protein, putative 0.0019 0.0012 0.0209
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0042 0.0065 0.0363
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0195 0.0192
Schistosoma mansoni alpha-glucosidase 0.0162 0.0349 0.0346
Onchocerca volvulus 0.0039 0.0058 0.0056
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0038 0.0218
Schistosoma mansoni hypothetical protein 0.1071 0.2503 0.2501
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0234 0.4205
Mycobacterium ulcerans beta-lactamase 0.0039 0.0058 0.1327
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0016 0.0004 0.0036
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0015 0.036
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0016 0.0004 0.0001
Echinococcus multilocularis aldo keto reductase 0.0195 0.0428 0.0425
Brugia malayi Tyrosine-protein kinase PR2 0.0016 0.0004 0.0002
Entamoeba histolytica hypothetical protein 0.0016 0.0004 0.0036
Schistosoma mansoni cell adhesion molecule 0.0058 0.0103 0.01
Onchocerca volvulus 0.2641 0.6222 0.6221
Echinococcus multilocularis c src tyrosine kinase 0.0016 0.0004 0.0001
Leishmania major DNA polymerase kappa, putative 0.0021 0.0015 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0004 0.0036
Onchocerca volvulus 0.0045 0.0074 0.0071
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0065 0.1459
Entamoeba histolytica hypothetical protein 0.0033 0.0043 0.0956
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Mycobacterium ulcerans hypothetical protein 0.0039 0.0058 0.1327
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0016 0.0004 0.0002
Schistosoma mansoni titin 0.0045 0.0074 0.0071
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0195 0.0428 0.0425
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0031 0.004 0.0719
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0045 0.0074 0.0071
Echinococcus granulosus tyrosine protein kinase Src64B 0.0016 0.0004 0.0001
Trichomonas vaginalis aldo-keto reductase, putative 0.0056 0.01 0.2282
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0074 0.0072
Entamoeba histolytica serine/threonine kinase, putative 0.0016 0.0004 0.0036
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0056 0.01 0.0586
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Echinococcus granulosus basement membrane specific heparan sulfate 0.0058 0.0103 0.01
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0236 0.0525 0.0522
Echinococcus multilocularis transfer RNA-Thr 0.0016 0.0004 0.0001
Onchocerca volvulus 0.0016 0.0004 0.0002
Trichomonas vaginalis aldo-keto reductase, putative 0.0195 0.0428 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.036
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0038 0.0218
Echinococcus granulosus sodium and chloride dependent glycine 0.0719 0.1669 0.1667
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0017 0.0014
Trypanosoma cruzi aldo/keto reductase, putative 0.0195 0.0428 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0719 0.1669 0.1667
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0021 0.0016 0.0318
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0015 0.0301
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0234 0.545
Schistosoma mansoni basigin related 0.0058 0.0103 0.01
Brugia malayi follicle stimulating hormone receptor 0.0241 0.0538 0.0535
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0016 0.0004 0.0001
Schistosoma mansoni hypothetical protein 0.0058 0.0103 0.01
Echinococcus granulosus contactin 0.0104 0.0211 0.0208
Schistosoma mansoni netrin receptor unc5 0.0058 0.0103 0.01
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0017 0.0014
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0015 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0004 0.0036
Trichomonas vaginalis TK family protein kinase 0.0016 0.0004 0.0036
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0104 0.0211 0.0209
Trichomonas vaginalis protein kinase atn1, putative 0.0016 0.0004 0.0036
Echinococcus granulosus zinc finger transcription factor gli2 0.0303 0.0684 0.0681
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0004 0.0096
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0015 0.0013
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0104 0.0211 0.0209
Schistosoma mansoni cpg binding protein 0.0032 0.0042 0.0039
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0016 0.0004 0.0036
Echinococcus granulosus cpg binding protein 0.0032 0.0042 0.0039
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0097 0.0094
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0719 0.1669 0.1667
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Brugia malayi Guanylyl cyclase protein 23 0.0016 0.0004 0.0002
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0031 0.004 0.0895
Echinococcus granulosus tyrosine protein kinase Srms 0.0016 0.0004 0.0001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0117 0.0243 0.024
Onchocerca volvulus 0.0045 0.0074 0.0071
Plasmodium falciparum protein kinase, putative 0.0016 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0016 0.0004 0.0036
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.002 0.0014 0.0287
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0016 0.0004 0.0001
Trypanosoma brucei importin beta-1 subunit, putative 0.0026 0.0028 0.0651
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0252 0.0564 0.0562
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Onchocerca volvulus 0.0719 0.1669 0.1667
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Loa Loa (eye worm) disorganized muscle protein 1 0.0045 0.0074 0.0072
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Brugia malayi hypothetical protein 0.0016 0.0004 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0031 0.004 0.0719
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0058 0.0103 0.01
Echinococcus multilocularis tyrosine protein kinase csk 0.0016 0.0004 0.0001
Brugia malayi intermediate filament protein 0.0026 0.0029 0.0026
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0031 0.004 0.0895
Loa Loa (eye worm) hypothetical protein 0.0039 0.0058 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Loa Loa (eye worm) TK/INSR protein kinase 0.0016 0.0004 0.0002
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0031 0.004 0.0895
Loa Loa (eye worm) hypothetical protein 0.0026 0.0028 0.0026
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0016 0.0004 0.0001
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0045 0.0074 0.0071
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0016 0.0004 0.0001
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0015 0.0014
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0117 0.0243 0.024
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Schistosoma mansoni peroxidasin 0.0058 0.0103 0.01
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0016 0.0004 0.0001
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0719 0.1669 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0015 0.0002 0.0035
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0081 0.0079
Toxoplasma gondii HEAT repeat-containing protein 0.0026 0.0028 0.0142
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0195 0.0428 0.0425
Echinococcus granulosus retinal guanylyl cyclase 2 0.0016 0.0004 0.0001
Entamoeba histolytica serine/threonine kinase, putative 0.0016 0.0004 0.0036
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0104 0.0211 0.0208
Echinococcus granulosus sodium and chloride dependent glycine 0.0719 0.1669 0.1667
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0081 0.0078
Trichomonas vaginalis aldo-keto reductase, putative 0.0195 0.0428 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0195 0.0428 0.0425
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0015
Echinococcus granulosus insulin receptor 0.0016 0.0004 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0014 0.0287
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0033 0.0043 0.004
Entamoeba histolytica tyrosin kinase, putative 0.0016 0.0004 0.0036
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0195 0.0428 0.0425
Brugia malayi beta-lactamase family protein 0.0039 0.0058 0.0056
Echinococcus multilocularis insulin receptor 0.0016 0.0004 0.0001
Loa Loa (eye worm) TK/ACK protein kinase 0.0016 0.0004 0.0002
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0058 0.0055
Echinococcus multilocularis raf serine:threonine protein kinase 0.0016 0.0004 0.0001
Echinococcus granulosus activin receptor type 0.0016 0.0004 0.0001
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0016 0.0004 0.0002
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Brugia malayi Prion-like- 0.0045 0.0074 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0004 0.0036
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0094 0.0188 0.0185
Brugia malayi Immunoglobulin I-set domain containing protein 0.0104 0.0211 0.0208
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0033 0.0043 0.004
Entamoeba histolytica aldose reductase, putative 0.0195 0.0428 1
Echinococcus granulosus tyrosine protein kinase shark 0.0016 0.0004 0.0001
Echinococcus multilocularis roundabout 2 0.0104 0.0211 0.0208
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0058 0.0055
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0016 0.0004 0.0001
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0097 0.0094
Schistosoma mansoni hypothetical protein 0.0058 0.0103 0.01
Trichomonas vaginalis aldo/keto reductase, putative 0.0195 0.0428 1
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0031 0.004 0.0719
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0019 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0077 0.0148 0.0146
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0074 0.0072
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Entamoeba histolytica hypothetical protein, conserved 0.0016 0.0004 0.0036
Echinococcus multilocularis survival motor neuron protein 1 0.024 0.0535 0.0532
Onchocerca volvulus 0.0016 0.0004 0.0002
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Loa Loa (eye worm) LAD-2 short isoform 0.0058 0.0103 0.0101
Onchocerca volvulus 0.0056 0.01 0.0097
Loa Loa (eye worm) oxidoreductase 0.0195 0.0428 0.0426
Schistosoma mansoni transient receptor potential channel 0.0137 0.029 0.0287
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0117 0.0243 0.024
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0016 0.0004 0.0036
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.002 0.0014 0.0254
Brugia malayi Immunoglobulin I-set domain containing protein 0.0104 0.0211 0.0208
Loa Loa (eye worm) hypothetical protein 0.024 0.0535 0.0533
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0038 0.084
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0016 0.0004 0.0001
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0058 0.1327
Loa Loa (eye worm) animal heme peroxidase 0.0045 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0039 0.0058 0.0056
Trypanosoma brucei Pseudokinase, putative 0.0016 0.0004 0.0096
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Entamoeba histolytica receptor protein kinase, putative 0.0016 0.0004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Echinococcus multilocularis neutral alpha glucosidase AB 0.0042 0.0065 0.0062
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0031 0.004 0.0719
Entamoeba histolytica acyl-coA synthetase, putative 0.002 0.0014 0.027
Entamoeba histolytica acyl-CoA synthetase, putative 0.002 0.0014 0.027
Loa Loa (eye worm) TK/FAK protein kinase 0.0016 0.0004 0.0002
Schistosoma mansoni potassium channel beta 0.0056 0.01 0.0097
Loa Loa (eye worm) hypothetical protein 0.0369 0.0841 0.0839
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0016 0.0004 0.0002
Echinococcus multilocularis tyrosine protein kinase pr2 0.0016 0.0004 0.0001
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0038 0.0205
Echinococcus multilocularis activated cdc42 kinase 1 0.0016 0.0004 0.0001
Plasmodium falciparum LCCL domain-containing protein 0.0016 0.0003 0.0006
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0234 0.545
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Onchocerca volvulus 0.0016 0.0004 0.0002
Brugia malayi integrin-linked kinase 0.0016 0.0004 0.0002
Loa Loa (eye worm) protein kinase domain-containing protein 0.0016 0.0004 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0195 0.0428 0.0425
Plasmodium vivax tyrosine kinase-like protein, putative 0.0016 0.0004 0.0014
Trichomonas vaginalis aldo-keto reductase, putative 0.0195 0.0428 1
Toxoplasma gondii hypothetical protein 0.0719 0.1669 1
Echinococcus granulosus voltage gated potassium channel subunit 0.0056 0.01 0.0097
Onchocerca volvulus 0.0195 0.0428 0.0425
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0016 0.0004 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Echinococcus granulosus epidermal growth factor receptor 0.0016 0.0004 0.0001
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0015 0.0318
Loa Loa (eye worm) hypothetical protein 0.0039 0.0058 0.0056
Echinococcus granulosus importin subunit beta 1 0.0026 0.0028 0.0025
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Onchocerca volvulus 0.0048 0.0081 0.0078
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0081 0.0078
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0234 0.545
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0103 0.0101
Echinococcus multilocularis zinc finger transcription factor gli2 0.0303 0.0684 0.0681
Brugia malayi hypothetical protein 0.0033 0.0043 0.0041
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0016 0.0004 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0016 0.0004 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0017 0.0015
Echinococcus granulosus tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus granulosus serotonin transporter 0.4235 1 1
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0038 0.0807
Echinococcus granulosus dna polymerase kappa 0.0021 0.0015 0.0013
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0195 0.0428 0.0425
Schistosoma mansoni ephrin receptor 0.0016 0.0004 0.0001
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0016 0.0004 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0097 0.0094
Entamoeba histolytica ankyrin repeat protein 0.0016 0.0004 0.0036
Echinococcus multilocularis sodium and chloride dependent glycine 0.0719 0.1669 0.1667
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Brugia malayi hypothetical protein 0.0178 0.0388 0.0385
Leishmania major hypothetical protein, conserved 0.0025 0.0024 0.0511
Echinococcus granulosus tyrosine protein kinase HCK 0.0016 0.0004 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0016 0.0004 0.0002
Leishmania major DNA polymerase eta, putative 0.0021 0.0015 0.0301
Schistosoma mansoni ap endonuclease 0.0038 0.0055 0.0052
Onchocerca volvulus 0.0195 0.0428 0.0425
Brugia malayi Fibronectin type III domain containing protein 0.0178 0.0388 0.0385
Entamoeba histolytica hypothetical protein 0.0016 0.0004 0.0036
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0234 0.0231
Brugia malayi beta-lactamase family protein 0.0039 0.0058 0.0056
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0719 0.1669 0.1667
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0031 0.004 0.0719
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0065 0.1459
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0016 0.0004 0.0036
Entamoeba histolytica hypothetical protein 0.0016 0.0004 0.0036
Onchocerca volvulus 0.0016 0.0004 0.0002
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0719 0.1669 0.1667
Echinococcus multilocularis lamin 0.0026 0.0029 0.0026
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0015
Echinococcus granulosus neuroglian 0.0104 0.0211 0.0208
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0016 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.4235 1 1
Echinococcus granulosus tyrosine protein kinase otk 0.0104 0.0211 0.0208
Echinococcus multilocularis peroxidasin 0.0104 0.0211 0.0208
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0015 0.0278
Onchocerca volvulus 0.0018 0.0009 0.0006
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0016 0.0004 0.0001
Schistosoma mansoni lipoxygenase 0.0094 0.0188 0.0185
Loa Loa (eye worm) hypothetical protein 0.0104 0.0211 0.0209
Leishmania major cytochrome p450-like protein 0.0031 0.004 0.088
Loa Loa (eye worm) hypothetical protein 0.0104 0.0211 0.0209
Trypanosoma brucei unspecified product 0.0021 0.0015 0.036
Onchocerca volvulus 0.0195 0.0428 0.0425
Schistosoma mansoni septate junction protein 0.0104 0.0211 0.0208
Echinococcus granulosus tyrosine protein kinase Blk 0.0016 0.0004 0.0001
Toxoplasma gondii ABC1 family protein 0.0039 0.0058 0.0326
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0195 0.0428 0.0425
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0082 0.0079
Echinococcus multilocularis lachesin 0.0104 0.0211 0.0208
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0016 0.0004 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0104 0.0211 0.0208
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Loa Loa (eye worm) one IG domain family member 0.0045 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0719 0.1669 0.1668
Brugia malayi Tyrosine-protein kinase abl-1 0.0016 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0012
Entamoeba histolytica hypothetical protein 0.0016 0.0004 0.0036
Echinococcus multilocularis roundabout 2 0.0282 0.0633 0.063
Echinococcus multilocularis Immunoglobulin 0.0178 0.0388 0.0385
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.084
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0038 0.0218
Plasmodium falciparum amino acid transporter, putative 0.0719 0.1669 1
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0017 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0004 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Schistosoma mansoni aldo-keto reductase 0.0195 0.0428 0.0425
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.036
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0117 0.0243 0.024
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0017 0.0014
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi RNA, U transporter 1 0.0074 0.0142 0.014
Loa Loa (eye worm) CAMK protein kinase 0.0045 0.0074 0.0072
Brugia malayi MH2 domain containing protein 0.0108 0.0223 0.022
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0017 0.0014
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0017 0.0014
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0016 0.0004 0.0036
Brugia malayi phosphofructokinase 0.0113 0.0234 0.0232
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Echinococcus multilocularis neuroglian 0.0223 0.0495 0.0493
Brugia malayi mbt repeat family protein 0.0048 0.0081 0.0078
Brugia malayi Transient-receptor-potential like protein 0.0077 0.0148 0.0145
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0014 0.0287
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0015 0.0278
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0017 0.0014
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0195 0.0192
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0031 0.004 0.0895
Trichomonas vaginalis aldo-keto reductase, putative 0.0195 0.0428 1
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi Immunoglobulin I-set domain containing protein 0.0178 0.0388 0.0385
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0015 0.0013
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0016 0.0004 0.0036
Entamoeba histolytica tyrosin kinase, putative 0.0016 0.0004 0.0036
Brugia malayi Receptor family ligand binding region containing protein 0.0016 0.0004 0.0002
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0077 0.0148 0.0145
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0065 0.1459
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0234 0.0231
Entamoeba histolytica serine/threonine kinase, putative 0.0016 0.0004 0.0036
Echinococcus granulosus Immunoglobulin 0.0058 0.0103 0.01
Echinococcus multilocularis tyrosine protein kinase csk 0.0016 0.0004 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0104 0.0211 0.0208
Loa Loa (eye worm) hypothetical protein 0.0282 0.0633 0.0631
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0058 0.1049
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0015 0.0318
Echinococcus multilocularis titin 0.0045 0.0074 0.0071
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0015 0.0301
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0016 0.0004 0.0001
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0055 0.129
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0074 0.0072
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0055 0.0052
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0015
Schistosoma mansoni sodium/chloride dependent transporter 0.0719 0.1669 0.1667
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.002 0.0014 0.0287
Echinococcus granulosus aldehyde reductase 0.0138 0.0294 0.0291
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0017 0.0014
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0001
Brugia malayi Heparan sulfate 0.0058 0.0103 0.0101
Brugia malayi CXXC zinc finger family protein 0.003 0.0038 0.0035
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0045 0.0074 0.0071
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0022
Plasmodium falciparum aldo-keto reductase, putative 0.0056 0.01 0.0586
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0015
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0017 0.0014
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0058 0.1049
Echinococcus multilocularis sodium and chloride dependent glycine 0.0719 0.1669 0.1667
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0234 0.545
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0301
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.0002
Echinococcus multilocularis short transient receptor potential channel 6 0.0137 0.029 0.0287
Schistosoma mansoni transient receptor potential channel 0.0137 0.029 0.0287
Loa Loa (eye worm) cytochrome P450 0.0031 0.004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0178 0.0388 0.0386
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0017 0.0014
Echinococcus multilocularis titin 0.0045 0.0074 0.0071
Trypanosoma brucei importin beta-1 subunit, putative 0.0026 0.0028 0.0651
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0104 0.0211 0.0208
Entamoeba histolytica serine/threonine kinase, putative 0.0016 0.0004 0.0036
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0081 0.0078
Plasmodium falciparum importin beta, putative 0.0026 0.0028 0.0156
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0234 0.0197
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0058 0.0103 0.01
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0195 0.0428 0.0425
Loa Loa (eye worm) hypothetical protein 0.013 0.0273 0.0271
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0017 0.0014
Mycobacterium ulcerans lipase LipD 0.0039 0.0058 0.1327
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0031 0.004 0.0895
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0719 0.1669 0.1667
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0017 0.0014
Schistosoma mansoni hypothetical protein 0.0045 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.0026 0.0027 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0004 0.0036
Brugia malayi Cytochrome P450 family protein 0.0031 0.004 0.0037
Trypanosoma brucei glycosyl hydrolase-like protein 0.0016 0.0003 0.006
Schistosoma mansoni sodium-dependent amino acid transporter 0.0719 0.1669 0.1667
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0195 0.0428 0.0425
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0017 0.0014
Brugia malayi SRC-1 0.0016 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0104 0.0211 0.0209
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Schistosoma mansoni serine/threonine RGC 0.0016 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0002
Brugia malayi SH2 domain containing protein 0.0016 0.0004 0.0002
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0031 0.004 0.088
Onchocerca volvulus 0.0045 0.0074 0.0071
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0019 0.0012 0.0044
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0058 0.1327
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi Immunoglobulin I-set domain containing protein 0.0062 0.0112 0.0109
Trichomonas vaginalis protein tyrosine kinase, putative 0.0016 0.0004 0.0036
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.004 0.088
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0058 0.1312
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0019 0.0012 0.0009
Toxoplasma gondii kringle domain-containing protein 0.0018 0.0009 0.0029
Onchocerca volvulus 0.0195 0.0428 0.0425
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0081 0.0078
Trichomonas vaginalis aldo/keto reductase, putative 0.0195 0.0428 1
Entamoeba histolytica alcohol dehydrogenase, putative 0.0056 0.01 0.2282
Brugia malayi latrophilin 2 splice variant baaae 0.0252 0.0564 0.0561
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0195 0.0193
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0058 0.1049
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0058 0.0103 0.01
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0104 0.0211 0.0208
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0055 0.1205
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0178 0.0388 0.0385
Echinococcus multilocularis voltage gated potassium channel subunit 0.0056 0.01 0.0097
Trypanosoma brucei aldo-keto reductase, putative 0.0195 0.0428 1
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0045 0.0074 0.0071
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0369 0.0841 0.0839
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0002
Brugia malayi mbt repeat family protein 0.0048 0.0081 0.0078
Loa Loa (eye worm) hypothetical protein 0.0104 0.0211 0.0209
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0195 0.0428 0.0425
Schistosoma mansoni basigin related 0.0058 0.0103 0.01
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0301
Echinococcus granulosus tyrosine protein kinase ABL1 0.0016 0.0004 0.0001
Onchocerca volvulus 0.0045 0.0074 0.0071
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0058 0.1312
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0055 0.1237
Entamoeba histolytica hypothetical protein 0.0016 0.0004 0.0036
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0016 0.0004 0.0001
Onchocerca volvulus 0.0045 0.0074 0.0071
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0055 0.5
Schistosoma mansoni cell adhesion molecule 0.0045 0.0074 0.0071
Leishmania major hypothetical protein, conserved 0.0016 0.0004 0.0036
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0001
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0031 0.004 0.0895
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Onchocerca volvulus 0.0045 0.0074 0.0071
Schistosoma mansoni cell adhesion molecule 0.0045 0.0074 0.0071
Echinococcus multilocularis aldo keto reductase 0.0195 0.0428 0.0425
Echinococcus multilocularis tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus granulosus fibroblast growth factor receptor 4 0.0016 0.0004 0.0001
Loa Loa (eye worm) oxidoreductase 0.0195 0.0428 0.0426
Echinococcus multilocularis snurportin 1 0.028 0.0628 0.0625
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0001
Schistosoma mansoni lipoxygenase 0.0065 0.0121 0.0118
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0195 0.0428 1
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0016 0.0004 0.0036
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0058 0.1049
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0015
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0719 0.1669 0.1667
Echinococcus granulosus tyrosine protein kinase Lyn 0.0016 0.0004 0.0001
Echinococcus multilocularis heat shock protein 70 0.0016 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Echinococcus multilocularis tyrosine protein kinase Abl 0.0016 0.0004 0.0001
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0015
Trichomonas vaginalis aldo-keto reductase, putative 0.0195 0.0428 1
Echinococcus granulosus snurportin 1 0.028 0.0628 0.0625
Onchocerca volvulus 0.0016 0.0004 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.036
Echinococcus granulosus hypothetical protein 0.0195 0.0428 0.0425
Entamoeba histolytica receptor protein kinase, putative 0.0016 0.0004 0.0036
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0058 0.0103 0.01
Schistosoma mansoni hypothetical protein 0.0045 0.0074 0.0071
Echinococcus multilocularis tumor protein p63 0.0683 0.1585 0.1582
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0031 0.004 0.088
Onchocerca volvulus 0.0016 0.0004 0.0002
Trichomonas vaginalis aldo-keto reductase, putative 0.0195 0.0428 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0195 0.0428 0.0425
Schistosoma mansoni coup transcription factor 0.0022 0.0017 0.0014
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0178 0.0388 0.0386
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0234 0.0232
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0002
Brugia malayi nuclear hormone receptor 0.0022 0.0017 0.0014
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0031 0.004 0.088
Schistosoma mansoni lamin 0.0026 0.0029 0.0026
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.0282 0.0633 0.0631
Echinococcus granulosus neuroglian 0.0223 0.0495 0.0493
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0097 0.0094
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Schistosoma mansoni netrin receptor unc5 0.0058 0.0103 0.01
Brugia malayi steroid hormone receptor 0.0022 0.0017 0.0014
Mycobacterium tuberculosis Possible penicillin-binding protein 0.025 0.0557 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0017 0.0014
Schistosoma mansoni titin 0.0045 0.0074 0.0071
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0015 0.036
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus granulosus receptor type guanylyl cyclase 0.0016 0.0004 0.0001
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0016 0.0004 0.0001
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0719 0.1669 0.1667
Schistosoma mansoni ephrin receptor 0.0016 0.0004 0.0001
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0016 0.0004 0.0001
Onchocerca volvulus 0.0039 0.0058 0.0056
Trichomonas vaginalis aldo-keto reductase, putative 0.0056 0.01 0.2282
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0195 0.0428 0.0425
Echinococcus multilocularis Immunoglobulin 0.0178 0.0388 0.0385
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0017 0.0014
Echinococcus multilocularis dna polymerase eta 0.0021 0.0015 0.0013
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi Raf kinase 0.0016 0.0004 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Plasmodium falciparum cysteine repeat modular protein 1 0.0018 0.0009 0.0043
Loa Loa (eye worm) TK/EGFR protein kinase 0.0016 0.0004 0.0002
Echinococcus multilocularis transient receptor potential gamma protein 0.0207 0.0455 0.0452
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0002
Echinococcus granulosus hemicentin 1 0.0104 0.0211 0.0208
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0038 0.0205
Toxoplasma gondii cytochrome p450 superfamily protein 0.0031 0.004 0.0215
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0002
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0055 0.032
Toxoplasma gondii aldose reductase, putative 0.0195 0.0428 0.2543
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0031 0.004 0.0895
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0017 0.0014
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0015
Brugia malayi Immunoglobulin I-set domain containing protein 0.2893 0.682 0.6819
Echinococcus granulosus titin 0.0045 0.0074 0.0071
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0719 0.1669 0.1667
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0031 0.004 0.0895
Trichomonas vaginalis aldo-keto reductase, putative 0.0056 0.01 0.2282
Echinococcus granulosus GPCR family 2 0.0117 0.0243 0.024
Leishmania major hypothetical protein, conserved 0.0018 0.0009 0.0151
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Echinococcus multilocularis Immunoglobulin subtype 0.0058 0.0103 0.01
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0103 0.0101
Loa Loa (eye worm) oxidoreductase 0.0195 0.0428 0.0426
Echinococcus granulosus tyrosine protein kinase Fyn 0.0016 0.0004 0.0001
Echinococcus granulosus raf serine:threonine protein kinase 0.0016 0.0004 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0031 0.004 0.0719
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0056 0.01 0.0098
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0719 0.1669 0.1668
Loa Loa (eye worm) hypothetical protein 0.0048 0.0081 0.0079
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0719 0.1669 0.1667
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0019 0.0012 0.0173
Schistosoma mansoni hypothetical protein 0.0031 0.004 0.0037
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0016 0.0004 0.0001
Schistosoma mansoni hypothetical protein 0.0117 0.0243 0.024
Echinococcus granulosus down syndrome cell adhesion 0.0045 0.0074 0.0071
Schistosoma mansoni lamin 0.0026 0.0029 0.0026
Echinococcus multilocularis tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus granulosus tyrosine protein kinase Fyn 0.0016 0.0004 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0016 0.0004 0.0036
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0024 0.0511
Trichomonas vaginalis importin beta-1, putative 0.0021 0.0016 0.0318
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0031 0.004 0.0895
Echinococcus multilocularis epidermal growth factor receptor 0.0016 0.0004 0.0001
Echinococcus multilocularis receptor type guanylyl cyclase 0.0016 0.0004 0.0001
Brugia malayi Immunoglobulin domain containing protein 0.0058 0.0103 0.0101
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Echinococcus multilocularis tyrosine protein kinase shark 0.0016 0.0004 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0016 0.0004 0.0001
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0038 0.084
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0015
Entamoeba histolytica alcohol dehydrogenase, putative 0.0056 0.01 0.2282
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0004 0.0036
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.002 0.0014 0.0287
Onchocerca volvulus 0.0195 0.0428 0.0425
Toxoplasma gondii aldo-keto reductase 0.0056 0.01 0.0573
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Mycobacterium ulcerans hypothetical protein 0.002 0.0014 0.0287
Trypanosoma cruzi importin beta-1 subunit, putative 0.0021 0.0016 0.0318
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0016 0.0004 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Schistosoma mansoni hemicentin 0.0045 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Schistosoma mansoni tyrosine kinase 0.012 0.0249 0.0247
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0016 0.0004 0.0036
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0016 0.0004 0.0001
Schistosoma mansoni hypothetical protein 0.0045 0.0074 0.0071
Schistosoma mansoni survival motor neuron protein 0.0049 0.0082 0.0079
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0016 0.0004 0.0001
Echinococcus multilocularis importin subunit beta 1 0.0026 0.0028 0.0025
Brugia malayi Prion-like- 0.0045 0.0074 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Onchocerca volvulus 0.0016 0.0004 0.0002
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0016 0.0004 0.0036
Echinococcus multilocularis tyrosine protein kinase csk 0.0016 0.0004 0.0001
Echinococcus granulosus insulin growth factor binding 0.0045 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.0178 0.0388 0.0386
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0719 0.1669 0.1667
Schistosoma mansoni nephrin 0.0104 0.0211 0.0208
Plasmodium falciparum protein kinase, putative 0.0016 0.0004 0.0014
Mycobacterium tuberculosis Conserved protein 0.0039 0.0058 0.1049
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0081 0.0078
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Brugia malayi Prion-like- 0.0104 0.0211 0.0208
Echinococcus multilocularis Immunoglobulin 0.0058 0.0103 0.01
Plasmodium vivax protein kinase, putative 0.0016 0.0004 0.0014
Brugia malayi Animal haem peroxidase family protein 0.0045 0.0074 0.0071
Echinococcus granulosus integrin linked protein kinase 0.0016 0.0004 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0031 0.004 0.0895
Brugia malayi hypothetical protein 0.0025 0.0024 0.0022
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0014 0.0287
Plasmodium vivax aldehyde reductase, putative 0.0056 0.01 0.0586
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0719 0.1669 0.1667
Leishmania major aldo-keto reductase-like protein 0.0195 0.0428 1
Schistosoma mansoni neuroglian 0.0104 0.0211 0.0208
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0058 0.1312
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Trypanosoma brucei cytochrome P450, putative 0.0031 0.004 0.0935
Loa Loa (eye worm) hypothetical protein 0.0178 0.0388 0.0386
Schistosoma mansoni nephrin related 0.0058 0.0103 0.01
Giardia lamblia Aldose reductase 0.0195 0.0428 1
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0016 0.0004 0.0001
Onchocerca volvulus Peroxidasin homolog 0.0045 0.0074 0.0071
Schistosoma mansoni hypothetical protein 0.0045 0.0074 0.0071
Onchocerca volvulus 0.0022 0.0017 0.0014
Schistosoma mansoni cellular tumor antigen P53 0.01 0.0203 0.02
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0045 0.0074 0.0071
Loa Loa (eye worm) SRC-1 0.0016 0.0004 0.0002
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0058 0.0103 0.01
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0016 0.0004 0.0001
Echinococcus multilocularis roundabout 2 0.0104 0.0211 0.0208
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.036
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0719 0.1669 0.1667
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0001
Entamoeba histolytica hypothetical protein 0.0016 0.0004 0.0036
Echinococcus granulosus aldo keto reductase 0.0195 0.0428 0.0425
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0004 0.0002
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0058 0.0103 0.01
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0055 0.0052
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0016 0.0004 0.0001
Echinococcus multilocularis tyrosine protein kinase HCK 0.0016 0.0004 0.0001
Mycobacterium leprae Possible oxidoreductase 0.0056 0.01 0.2067
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0016 0.0004 0.0001
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0058 0.1049
Echinococcus granulosus nephrin 0.0045 0.0074 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi Cytochrome P450 family protein 0.0031 0.004 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0017 0.0014
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0195 0.0192
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0014 0.0287
Schistosoma mansoni cell adhesion molecule 0.0104 0.0211 0.0208
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0019 0.0012 0.0209
Onchocerca volvulus 0.0045 0.0074 0.0071
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0031 0.004 0.0719
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0016 0.0004 0.0001
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0081 0.0078
Echinococcus multilocularis aldo keto reductase 0.0195 0.0428 0.0425
Echinococcus granulosus netrin receptor unc 5 0.0058 0.0103 0.01
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0031 0.004 0.0895
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Onchocerca volvulus 0.0016 0.0004 0.0002
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0058 0.0103 0.01
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0058 0.0056
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0029 0.0027
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.084
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Echinococcus multilocularis tyrosine protein kinase 0.0016 0.0004 0.0001
Brugia malayi hypothetical protein 0.0058 0.0103 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0004 0.0036
Schistosoma mansoni transient receptor potential channel 0.0207 0.0455 0.0452
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0004 0.0002
Schistosoma mansoni myosin-binding protein-related 0.0045 0.0074 0.0071
Echinococcus multilocularis protein kinase 0.0016 0.0004 0.0001
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0234 0.5477
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0031 0.004 0.0719
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0031 0.004 0.0719
Brugia malayi Immunoglobulin domain containing protein 0.0058 0.0103 0.0101
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0058 0.0103 0.0101
Entamoeba histolytica hypothetical protein 0.0016 0.0004 0.0036
Trichomonas vaginalis esterase, putative 0.0039 0.0058 0.1312
Echinococcus multilocularis titin 0.0045 0.0074 0.0071
Plasmodium falciparum tyrosine kinase-like protein 0.0016 0.0004 0.0014
Schistosoma mansoni transient receptor potential channel 4 0.0207 0.0455 0.0452
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0016 0.0004 0.0036
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0719 0.1669 0.1667
Schistosoma mansoni titin 0.0045 0.0074 0.0071
Loa Loa (eye worm) serotonin transporter b 0.4235 1 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0195 0.0192
Echinococcus granulosus activated cdc42 kinase 1 0.0016 0.0004 0.0001
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0056 0.01 0.0097
Brugia malayi kettin 0.0045 0.0074 0.0071
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0016 0.0004 0.0001
Echinococcus granulosus neutral alpha glucosidase AB 0.0042 0.0065 0.0062
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0004 0.0036
Brugia malayi AMP-binding enzyme family protein 0.002 0.0014 0.0011
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0301
Loa Loa (eye worm) hypothetical protein 0.0207 0.0455 0.0453
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0065 0.1459
Echinococcus granulosus short transient receptor potential channel 6 0.0137 0.029 0.0287
Schistosoma mansoni nephrin 0.0223 0.0495 0.0493
Entamoeba histolytica hypothetical protein 0.0016 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0104 0.0211 0.0208
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0016 0.0004 0.0001
Brugia malayi hypothetical protein 0.0016 0.0004 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0234 0.545
Onchocerca volvulus 0.0045 0.0074 0.0071
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Schistosoma mansoni nephrin related 0.0045 0.0074 0.0071
Brugia malayi ephrin receptor 1 precursor 0.0016 0.0004 0.0002
Trypanosoma brucei Flagellum attachment zone protein 20 0.0016 0.0004 0.0096
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0178 0.0388 0.0385
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0031 0.004 0.0935
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0016 0.0004 0.0096
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0031 0.004 0.0895
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0031 0.004 0.0895
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0017 0.0014
Echinococcus multilocularis tissue type plasminogen activator 0.0018 0.0009 0.0006
Echinococcus multilocularis lysosomal alpha glucosidase 0.0188 0.0411 0.0408
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0002
Echinococcus multilocularis netrin receptor unc 5 0.0058 0.0103 0.01
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.4235 1 1
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi 6-phosphofructokinase 0.0113 0.0234 0.0232
Echinococcus granulosus low density lipoprotein receptor ldl 0.0058 0.0103 0.01
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0055 0.0053
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0016 0.0004 0.0001
Onchocerca volvulus 0.0016 0.0004 0.0002
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0045 0.0074 0.0071
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0195 0.0428 1
Schistosoma mansoni pol-related 0.0195 0.0428 0.0425
Brugia malayi SH2 domain containing protein 0.0016 0.0004 0.0002
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0017 0.0015
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0058 0.0103 0.01
Plasmodium vivax multidomain scavenger receptor, putative 0.0016 0.0003 0.0006
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Echinococcus granulosus retinal guanylyl cyclase 2 0.0016 0.0004 0.0001
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.0065 0.1459
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Trypanosoma cruzi protein kinase, putative 0.0016 0.0004 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0017 0.0015
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0104 0.0211 0.0209
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Loa Loa (eye worm) TK/RYK protein kinase 0.0016 0.0004 0.0002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0017 0.0014
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0104 0.0211 0.0209
Echinococcus granulosus intermediate filament protein 0.0026 0.0029 0.0026
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0031 0.004 0.0895
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0015 0.0301
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0719 0.1669 0.1668
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0017 0.0014
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Echinococcus granulosus leucine rich repeat containing protein 4 0.0045 0.0074 0.0071
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Onchocerca volvulus 0.0026 0.0029 0.0026
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0016 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0719 0.1669 0.1668
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0038 0.0036
Loa Loa (eye worm) CYP4Cod1 0.0031 0.004 0.0038
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0056 0.01 0.2282
Brugia malayi Immunoglobulin I-set domain containing protein 0.0104 0.0211 0.0208
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0056 0.01 0.0573
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0016 0.0004 0.0001
Brugia malayi Latrophilin receptor protein 2 0.0117 0.0243 0.024
Onchocerca volvulus 0.0016 0.0004 0.0002
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0029 0.0026
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0031 0.004 0.0719
Brugia malayi Prion-like- 0.0045 0.0074 0.0071
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0241 0.0538 0.0536
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Leishmania major protein kinase, putative 0.0016 0.0004 0.0036
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0058 0.0055
Entamoeba histolytica serine/threonine kinase, putative 0.0016 0.0004 0.0036
Entamoeba histolytica cysteine surface protein, putative 0.0016 0.0004 0.0036
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0017 0.0014
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0719 0.1669 1
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0234 0.0231
Echinococcus granulosus Immunoglobulin 0.0058 0.0103 0.01
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0038 0.0205
Echinococcus granulosus lysosomal alpha glucosidase 0.0188 0.0411 0.0408
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0719 0.1669 0.1667
Schistosoma mansoni septate junction protein 0.0104 0.0211 0.0208
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.004 0.0038
Echinococcus granulosus tyrosine protein kinase csk 0.0016 0.0004 0.0001
Trypanosoma cruzi protein kinase, putative 0.0016 0.0004 0.0036
Loa Loa (eye worm) TK protein kinase 0.0062 0.0112 0.011
Echinococcus granulosus aldo keto reductase 0.0195 0.0428 0.0425
Entamoeba histolytica aldose reductase, putative 0.0195 0.0428 1
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0017 0.0014
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0017 0.0014
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.013 0.0273 0.0271
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0017 0.0014
Onchocerca volvulus Peroxidasin homolog 0.0045 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Echinococcus multilocularis geminin 0.1071 0.2503 0.2501
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0016 0.0004 0.0001
Echinococcus granulosus natriuretic peptide receptor 1 0.0016 0.0004 0.0001
Mycobacterium tuberculosis Probable oxidoreductase 0.0195 0.0428 0.7676
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0027
Echinococcus granulosus dna polymerase eta 0.0021 0.0015 0.0013
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0015 0.0301
Schistosoma mansoni transcription factor LCR-F1 0.0033 0.0043 0.004
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0017 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.084
Schistosoma mansoni cpg binding protein 0.003 0.0038 0.0035
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0058 0.0056
Loa Loa (eye worm) TK/DDR protein kinase 0.0016 0.0004 0.0002
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0017 0.0014
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Onchocerca volvulus 0.0045 0.0074 0.0071
Schistosoma mansoni cpg binding protein 0.0032 0.0042 0.0039
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0017 0.0014
Loa Loa (eye worm) transcription factor SMAD2 0.0108 0.0223 0.0221
Brugia malayi Immunoglobulin I-set domain containing protein 0.0104 0.0211 0.0208
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0031 0.004 0.0895
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0017 0.0015
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0024 0.0135
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi Leucine Rich Repeat family protein 0.0045 0.0074 0.0071
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0024 0.0569
Schistosoma mansoni importin beta-1 0.0026 0.0028 0.0025
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0104 0.0211 0.0208
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0017 0.0014
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0234 0.0232
Trypanosoma brucei glucosidase, putative 0.0042 0.0065 0.151
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0031 0.004 0.0719
Loa Loa (eye worm) hypothetical protein 0.0104 0.0211 0.0209
Leishmania major cytochrome p450-like protein 0.0031 0.004 0.088
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0104 0.0211 0.0208
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0058 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.036
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0117 0.0243 0.024
Loa Loa (eye worm) hypothetical protein 0.0117 0.0243 0.0241
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0002
Echinococcus granulosus roundabout 2 0.0282 0.0633 0.063
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0018 0.0009 0.0043
Onchocerca volvulus 0.0049 0.0082 0.0079
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0031 0.004 0.0895
Plasmodium falciparum transporter, putative 0.0719 0.1669 1
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Entamoeba histolytica hypothetical protein 0.0033 0.0043 0.0956
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Echinococcus multilocularis transfer RNA-Phe 0.0045 0.0074 0.0071
Brugia malayi hypothetical protein 0.0016 0.0004 0.0002
Brugia malayi AMP-binding enzyme family protein 0.002 0.0014 0.0011
Echinococcus multilocularis natriuretic peptide receptor 1 0.0016 0.0004 0.0001
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Entamoeba histolytica hypothetical protein 0.0016 0.0004 0.0036
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0195 0.0428 0.0425
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.004 0.0038
Onchocerca volvulus 0.0045 0.0074 0.0071
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0024 0.0135
Plasmodium falciparum protein kinase, putative 0.0016 0.0004 0.0014
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0719 0.1669 1
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0031 0.004 0.0719
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0058 0.0103 0.01
Brugia malayi Disorganized muscle protein 1 0.0045 0.0074 0.0071
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0055 0.0053
Echinococcus multilocularis serotonin transporter 0.4235 1 1
Echinococcus multilocularis cpg binding protein 0.0032 0.0042 0.0039
Loa Loa (eye worm) hypothetical protein 0.0719 0.1669 0.1668
Echinococcus granulosus lachesin 0.0104 0.0211 0.0208
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Schistosoma mansoni alpha glucosidase 0.0042 0.0065 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Echinococcus granulosus titin 0.0045 0.0074 0.0071
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0016 0.0004 0.0036
Echinococcus multilocularis down syndrome cell adhesion 0.0045 0.0074 0.0071
Trypanosoma brucei protein kinase, putative 0.0016 0.0004 0.0096
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0031 0.004 0.0719
Brugia malayi Cytochrome P450 family protein 0.0031 0.004 0.0037
Brugia malayi protein-tyrosine kinase 0.0016 0.0004 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.036
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0195 0.0428 1
Schistosoma mansoni hypothetical protein 0.0117 0.0243 0.024
Loa Loa (eye worm) hypothetical protein 0.0039 0.0058 0.0056
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0719 0.1669 0.1667
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0074 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0017 0.0015
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0065 0.1459
Echinococcus granulosus tyrosine protein kinase pr2 0.0016 0.0004 0.0001
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0016 0.0004 0.0002
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0031 0.004 0.088
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0074 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0719 0.1669 0.1668
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0016 0.0004 0.0001
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0058 0.1312
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0045 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.0039 0.0058 0.0056
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0104 0.0211 0.0209
Schistosoma mansoni cytochrome P450 0.0031 0.004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0002
Echinococcus multilocularis GPCR, family 2 0.0117 0.0243 0.024
Onchocerca volvulus 0.0045 0.0074 0.0071
Echinococcus granulosus activated cdc42 kinase 1 0.0016 0.0004 0.0001
Leishmania major alpha glucosidase II subunit, putative 0.0042 0.0065 0.1459
Brugia malayi hypothetical protein 0.013 0.0273 0.027
Brugia malayi Kringle domain containing protein 0.0018 0.0009 0.0006
Onchocerca volvulus 0.0016 0.0004 0.0002
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0016 0.0004 0.0001
Loa Loa (eye worm) oxidoreductase 0.0195 0.0428 0.0426
Schistosoma mansoni hypothetical protein 0.0049 0.0082 0.0079
Mycobacterium tuberculosis Conserved protein 0.0039 0.0058 0.1049
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0031 0.004 0.0719
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0058 0.0103 0.0101
Schistosoma mansoni roundabout 0.0104 0.0211 0.0208
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0103 0.0101
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0058 0.0103 0.01
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0016 0.0004 0.0002
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0097 0.0094
Brugia malayi hypothetical protein 0.0016 0.0004 0.0002
Echinococcus multilocularis twitchin 0.0045 0.0074 0.0071
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Echinococcus granulosus tyrosine kinase 0.0016 0.0004 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0074 0.0071
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0058 0.1312
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0195 0.0428 0.0425
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0199 0.0436 0.0433
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0024 0.0121
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0017 0.0014
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0001
Echinococcus granulosus tyrosine protein kinase 0.0016 0.0004 0.0001
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0021 0.0016 0.0318
Schistosoma mansoni tyrosine protein kinase 0.0016 0.0004 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Echinococcus multilocularis ephrin type A receptor 4 A 0.0016 0.0004 0.0001
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0016 0.0004 0.0001
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0234 0.545
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi Protein kinase domain containing protein 0.0034 0.0047 0.0045
Mycobacterium leprae Probable lipase LipE 0.0039 0.0058 0.107
Schistosoma mansoni slit 0.0045 0.0074 0.0071
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0024 0.0135
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0195 0.0428 0.0425
Entamoeba histolytica hypothetical protein 0.0016 0.0004 0.0036
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0015 0.0013
Plasmodium falciparum aldehyde reductase, putative 0.0056 0.01 0.0586
Trichomonas vaginalis aldo-keto reductase, putative 0.0195 0.0428 1
Plasmodium vivax importin-beta 2, putative 0.0026 0.0028 0.0156
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0055 0.1237
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Plasmodium falciparum tyrosine kinase-like protein 0.0016 0.0004 0.0014
Echinococcus granulosus retinal guanylyl cyclase 2 0.0016 0.0004 0.0001
Schistosoma mansoni cell adhesion molecule 0.0045 0.0074 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0719 0.1669 0.1668
Brugia malayi basement membrane proteoglycan 0.0058 0.0103 0.0101
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.0002
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0016 0.0004 0.0002
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0719 0.1669 0.1667
Plasmodium vivax amine transporter, putative 0.0719 0.1669 1
Loa Loa (eye worm) TK/KIN16 protein kinase 0.2893 0.682 0.6819
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0195 0.0428 0.0425
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0195 0.0428 1
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.0002
Echinococcus multilocularis lysosomal alpha glucosidase 0.0188 0.0411 0.0408
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0031 0.004 0.0895
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0369 0.0841 0.0838
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0031 0.004 0.0895
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Mycobacterium leprae Conserved hypothetical protein 0.0138 0.0294 0.6765
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0234 0.0232
Mycobacterium leprae Conserved hypothetical protein 0.0031 0.004 0.0626
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0058 0.1312
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Schistosoma mansoni hypothetical protein 0.0045 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Entamoeba histolytica hypothetical protein 0.0021 0.0016 0.0318
Brugia malayi beta-lactamase 0.0039 0.0058 0.0056
Echinococcus multilocularis protein kinase 0.0016 0.0004 0.0001
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0058 0.0103 0.01
Brugia malayi Peroxidasin 0.0104 0.0211 0.0208
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0074 0.0072
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0016 0.0004 0.0036
Brugia malayi protein unc-22 0.0045 0.0074 0.0071
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0016 0.0004 0.0002
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0017 0.0014
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Schistosoma mansoni septate junction protein 0.0058 0.0103 0.01
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0016 0.0004 0.0001
Onchocerca volvulus Putative titin 0.0045 0.0074 0.0071
Loa Loa (eye worm) oxidoreductase 0.0195 0.0428 0.0426
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0042 0.0065 0.0063
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0195 0.0428 0.0425
Brugia malayi Glycosyl hydrolases family 31 protein 0.0042 0.0065 0.0062
Schistosoma mansoni cell adhesion molecule 0.0058 0.0103 0.01
Brugia malayi NADH-dependent xylose reductase 0.0056 0.01 0.0097
Schistosoma mansoni hypothetical protein 0.0033 0.0043 0.004
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0234 0.545
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0195 0.0428 0.0425
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0012
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0031 0.004 0.0895
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Schistosoma mansoni septate junction protein 0.0058 0.0103 0.01
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0016 0.0004 0.0001
Echinococcus granulosus kinase suppressor of Ras 1 0.0016 0.0004 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0065 0.1459
Entamoeba histolytica aldose reductase, putative 0.0195 0.0428 1
Echinococcus multilocularis aldo keto reductase 0.0195 0.0428 0.0425
Leishmania major prostaglandin f synthase, putative 0.0195 0.0428 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0188 0.0411 0.0409
Schistosoma mansoni hypothetical protein 0.0117 0.0243 0.024
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Echinococcus granulosus roundabout 2 0.0104 0.0211 0.0208
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0016 0.0004 0.0001
Entamoeba histolytica tyrosin kinase, putative 0.0016 0.0004 0.0036
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0001
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0055 0.0097 0.0095
Onchocerca volvulus Huntingtin homolog 0.013 0.0273 0.027
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0058 0.1312
Loa Loa (eye worm) TK/ABL protein kinase 0.0016 0.0004 0.0002
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0195 0.0428 1
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus granulosus geminin 0.1071 0.2503 0.2501
Echinococcus granulosus c src tyrosine kinase 0.0016 0.0004 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0017 0.0015
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0016 0.0004 0.0001
Brugia malayi cytochrome P450 0.0031 0.004 0.0037
Schistosoma mansoni titin 0.0045 0.0074 0.0071
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0058 0.107
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0017 0.0014
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0016 0.0004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0719 0.1669 0.1667
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0029 0.0027
Mycobacterium ulcerans hypothetical protein 0.0056 0.01 0.2294
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0845 0.1968 0.1965
Schistosoma mansoni titin 0.0104 0.0211 0.0208
Onchocerca volvulus 0.0026 0.0029 0.0026
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0001
Echinococcus granulosus ephrin type A receptor 4 A 0.0016 0.0004 0.0001
Loa Loa (eye worm) TK/CSK protein kinase 0.0016 0.0004 0.0002
Trichomonas vaginalis ran, putative 0.0019 0.0012 0.0209
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0195 0.0428 0.0425
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0178 0.0388 0.0385
Trichomonas vaginalis aldo-keto reductase, putative 0.0195 0.0428 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0719 0.1669 0.1667
Echinococcus granulosus Immunoglobulin 0.0178 0.0388 0.0385
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0019 0.0012 0.0009
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0055 0.0992
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0195 0.0192
Loa Loa (eye worm) hypothetical protein 0.0236 0.0525 0.0523
Schistosoma mansoni vesicular amine transporter 0.0185 0.0404 0.0401
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0017 0.0014
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Echinococcus multilocularis short transient receptor potential channel 6 0.0137 0.029 0.0287
Echinococcus multilocularis epidermal growth factor receptor 0.0016 0.0004 0.0001
Echinococcus granulosus protein tyrosine kinase 0.0016 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Brugia malayi Immunoglobulin I-set domain containing protein 0.0104 0.0211 0.0208
Brugia malayi C-terminal src kinase protein 1 0.0016 0.0004 0.0002
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0195 0.0428 0.0425
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0016 0.0004 0.0001
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0081 0.0078
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0016 0.0004 0.0002
Echinococcus granulosus peroxidasin 0.0104 0.0211 0.0208
Loa Loa (eye worm) hypothetical protein 0.0058 0.0103 0.0101
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.084
Mycobacterium leprae putative cytochrome p450 0.0031 0.004 0.0626
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0017 0.0014
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Echinococcus granulosus defective proboscis extension response 0.0178 0.0388 0.0385
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0016 0.0004 0.0001
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0017 0.0014
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0058 0.1049
Loa Loa (eye worm) hypothetical protein 0.0178 0.0388 0.0386
Onchocerca volvulus Netrin receptor homolog 0.0045 0.0074 0.0071
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0016 0.0004 0.0001
Loa Loa (eye worm) serine/threonine protein kinase 0.0016 0.0004 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0195 0.0192
Schistosoma mansoni hypothetical protein 0.0045 0.0074 0.0071
Schistosoma mansoni titin 0.0045 0.0074 0.0071
Schistosoma mansoni hypothetical protein 0.1071 0.2503 0.2501
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0015 0.036
Loa Loa (eye worm) TK/Met protein kinase 0.0016 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0014
Brugia malayi hypothetical protein 0.024 0.0535 0.0532
Onchocerca volvulus 0.003 0.0038 0.0035
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0065 0.1459
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0019 0.0012 0.0057
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0016 0.0004 0.0036
Leishmania major 4-coumarate:coa ligase-like protein 0.002 0.0014 0.027
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0017 0.0014
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0016 0.0004 0.0036
Echinococcus granulosus transient receptor potential gamma protein 0.0207 0.0455 0.0452
Brugia malayi AMP-binding enzyme family protein 0.002 0.0014 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.01 0.2282
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0058 0.1364
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0001
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0234 0.5457
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.036
Echinococcus multilocularis protein KINase family member (kin 25) 0.0016 0.0004 0.0001
Echinococcus multilocularis 0.0045 0.0074 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi Cytochrome P450 family protein 0.0031 0.004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0719 0.1669 0.1668
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0002
Schistosoma mansoni hypothetical protein 0.0045 0.0074 0.0071
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0016 0.0004 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0017 0.0014
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0062 0.0112 0.0109
Trichomonas vaginalis aldo/keto reductase, putative 0.0195 0.0428 1
Loa Loa (eye worm) projectin 0.0045 0.0074 0.0072
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0017 0.0014
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0719 0.1669 0.1667
Loa Loa (eye worm) latrophilin receptor protein 2 0.0117 0.0243 0.0241
Echinococcus granulosus short transient receptor potential channel 6 0.0137 0.029 0.0287
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0055 0.1237
Loa Loa (eye worm) hypothetical protein 0.0104 0.0211 0.0209
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.004 0.088
Brugia malayi Glycosyl hydrolases family 31 protein 0.0188 0.0411 0.0408
Echinococcus granulosus survival motor neuron protein 1 0.024 0.0535 0.0532
Schistosoma mansoni ap endonuclease 0.0038 0.0055 0.0052
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0017 0.0014
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.0065 0.1459
Schistosoma mansoni aldo-keto reductase 0.0195 0.0428 0.0425
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0031 0.004 0.0719
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Leishmania major 4-coumarate:coa ligase-like protein 0.002 0.0014 0.027
Loa Loa (eye worm) hypothetical protein 0.01 0.0203 0.0201
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0016 0.0004 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0103 0.0101
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0015 0.0013
Leishmania major hypothetical protein, conserved 0.0039 0.0058 0.1312
Loa Loa (eye worm) solute carrier family 6 member 4 0.4235 1 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0016 0.0004 0.0001
Entamoeba histolytica hypothetical protein 0.0016 0.0004 0.0036
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0017 0.0015
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0719 0.1669 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0055 0.032
Loa Loa (eye worm) TK/EPH protein kinase 0.0016 0.0004 0.0002
Toxoplasma gondii hypothetical protein 0.0719 0.1669 1
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0017 0.0014
Schistosoma mansoni hypothetical protein 0.0302 0.0682 0.0679
Giardia lamblia DINP protein human, muc B family 0.0021 0.0015 0.0266
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0234 0.545
Echinococcus multilocularis Immunoglobulin 0.0058 0.0103 0.01
Treponema pallidum sodium- and chloride- dependent transporter 0.4235 1 1
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0056 0.01 0.2282
Loa Loa (eye worm) TK/ALK protein kinase 0.0016 0.0004 0.0002
Echinococcus multilocularis musashi 0.0026 0.0029 0.0026
Trichomonas vaginalis sucrase-isomaltase, putative 0.0042 0.0065 0.1459
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0195 0.0428 0.0425
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0055 0.1237
Echinococcus granulosus tyrosine protein kinase Fyn 0.0016 0.0004 0.0001
Echinococcus granulosus tyrosine protein kinase csk 0.0016 0.0004 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0017 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0031 0.004 0.0719
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0004 0.0001
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0004 0.0036
Trypanosoma brucei prostaglandin f synthase 0.0195 0.0428 1
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0001
Schistosoma mansoni titin 0.0045 0.0074 0.0071
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0016 0.0004 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.007 0.0132 0.013
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0017 0.0014
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Echinococcus granulosus aldo keto reductase 0.0195 0.0428 0.0425
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0074 0.0072
Onchocerca volvulus 0.002 0.0014 0.0011
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0016 0.0004 0.0036
Brugia malayi basement membrane proteoglycan precursor 0.0058 0.0103 0.0101
Echinococcus multilocularis hemicentin 1 0.0104 0.0211 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0103 0.0101
Loa Loa (eye worm) TK/ROR protein kinase 0.008 0.0155 0.0153
Plasmodium vivax tyrosine kinase-like protein, putative 0.0016 0.0004 0.0014
Schistosoma mansoni cell adhesion molecule 0.0104 0.0211 0.0208
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Echinococcus granulosus epidermal growth factor receptor 0.0016 0.0004 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0058 0.0103 0.0101
Schistosoma mansoni alpha-glucosidase 0.0162 0.0349 0.0346
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.0002
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0016 0.0004 0.0002
Leishmania major cytochrome p450-like protein 0.0031 0.004 0.088
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0058 0.0103 0.01
Schistosoma mansoni hypothetical protein 0.0058 0.0103 0.01
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0058 0.0103 0.01
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0016 0.0004 0.0002
Onchocerca volvulus 0.0016 0.0004 0.0002
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0004 0.0002
Schistosoma mansoni cell adhesion molecule 0.0236 0.0525 0.0522
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0094 0.0188 0.0185
Echinococcus multilocularis transient receptor potential ion channel A 0.02 0.0439 0.0436
Echinococcus multilocularis tyrosine protein kinase Blk 0.0016 0.0004 0.0001
Onchocerca volvulus 0.0719 0.1669 0.1667
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0058 0.0103 0.01
Giardia lamblia Aldose reductase 0.0195 0.0428 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0104 0.0211 0.0208
Echinococcus granulosus titin 0.0045 0.0074 0.0071
Brugia malayi Zinc finger, C2H2 type family protein 0.0303 0.0684 0.0681
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0045 0.0074 0.0071
Brugia malayi ecdysteroid receptor 0.0022 0.0017 0.0014
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0031 0.004 0.0719
Schistosoma mansoni cell adhesion molecule 0.0104 0.0211 0.0208
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0097 0.0094
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0019 0.0012 0.0209
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0234 0.545
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0031 0.004 0.0719
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Mycobacterium tuberculosis Conserved protein 0.0039 0.0058 0.1049
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0234 0.5323
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0045 0.0074 0.0072
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0055 0.1252
Echinococcus granulosus cytochrome P450 2K1 0.0031 0.004 0.0037
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0017 0.0014
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0195 0.0428 0.0425
Schistosoma mansoni DNA polymerase eta 0.0021 0.0015 0.0013
Onchocerca volvulus Tyrosine kinase homolog 0.2702 0.6368 0.6367
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0055 0.0017
Loa Loa (eye worm) hypothetical protein 0.0039 0.0058 0.0056
Echinococcus multilocularis protein tyrosine kinase 0.0016 0.0004 0.0001
Toxoplasma gondii exonuclease III APE 0.0038 0.0055 0.0306
Brugia malayi Calcitonin receptor-like protein seb-1 0.0369 0.0841 0.0838
Mycobacterium tuberculosis Conserved protein 0.0056 0.01 0.1788
Onchocerca volvulus 0.0016 0.0004 0.0002
Echinococcus multilocularis neuroglian 0.0104 0.0211 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0031 0.004 0.0719
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0031 0.004 0.0895
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0062 0.0112 0.0109
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0016 0.0004 0.0001
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Onchocerca volvulus 0.0719 0.1669 0.1667
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0195 0.0428 0.0425
Echinococcus granulosus titin 0.0045 0.0074 0.0071
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0081 0.0078
Echinococcus granulosus titin 0.0045 0.0074 0.0071
Brugia malayi Immunoglobulin domain containing protein 0.0058 0.0103 0.0101
Trichomonas vaginalis aldo-keto reductase, putative 0.0195 0.0428 1
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0195 0.0428 1
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Schistosoma mansoni hypothetical protein 0.0117 0.0243 0.024
Schistosoma mansoni hypothetical protein 0.0058 0.0103 0.01
Schistosoma mansoni intermediate filament proteins 0.0026 0.0029 0.0026
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.0002
Brugia malayi hypothetical protein 0.0719 0.1669 0.1667
Trichomonas vaginalis STE family protein kinase 0.0016 0.0004 0.0036
Echinococcus multilocularis tyrosine protein kinase otk 0.0104 0.0211 0.0208
Entamoeba histolytica tyrosine kinase, putative 0.0016 0.0004 0.0036
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0301
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0055 0.1237
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Echinococcus multilocularis aldehyde reductase 0.0138 0.0294 0.0291
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0017 0.0014
Brugia malayi Immunoglobulin I-set domain containing protein 0.0104 0.0211 0.0208
Onchocerca volvulus 0.01 0.0203 0.02
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0015 0.0301
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0234 0.0231
Echinococcus granulosus protein kinase 0.0016 0.0004 0.0001
Onchocerca volvulus 0.0195 0.0428 0.0425
Entamoeba histolytica Ran family GTPase 0.0019 0.0012 0.0209
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0001
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0002
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0016 0.0004 0.0002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0071
Trypanosoma cruzi aldo-keto reductase 0.0195 0.0428 1
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0199 0.0436 0.0433
Trichomonas vaginalis aldo-keto reductase, putative 0.0195 0.0428 1
Echinococcus multilocularis titin 0.0045 0.0074 0.0071
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0074 0.0072
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Entamoeba histolytica serine/threonine kinase, putative 0.0016 0.0004 0.0036
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0014 0.0254
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0004 0.0001
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0016 0.0004 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0056 0.01 0.0097
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0017 0.0014
Schistosoma mansoni basigin related 0.0058 0.0103 0.01
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Echinococcus multilocularis 0.0031 0.004 0.0037
Echinococcus granulosus tissue type plasminogen activator 0.0018 0.0009 0.0006
Trypanosoma cruzi aldo/keto reductase, putative 0.0056 0.01 0.2282
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0004 0.0001
Trichomonas vaginalis maltase-glucoamylase, putative 0.0042 0.0065 0.1459
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0009 0.0151
Loa Loa (eye worm) MBCTL1 0.0055 0.0097 0.0095
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0072
Schistosoma mansoni titin 0.0045 0.0074 0.0071
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0055 0.1237
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0017 0.0014
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.004 0.0038
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0024 0.0511
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Echinococcus multilocularis insulin growth factor binding 0.0045 0.0074 0.0071
Schistosoma mansoni sodium/chloride dependent transporter 0.0719 0.1669 0.1667
Echinococcus multilocularis tyrosine protein kinase csk 0.0016 0.0004 0.0001
Echinococcus granulosus lamin dm0 0.0026 0.0029 0.0026
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0016 0.0004 0.0036
Schistosoma mansoni protein tyrosine kinase 0.0016 0.0004 0.0001
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0016 0.0004 0.0036
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0004 0.0036
Loa Loa (eye worm) MH2 domain-containing protein 0.0108 0.0223 0.0221
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0016 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0012
Brugia malayi 6-phosphofructokinase 0.0113 0.0234 0.0232
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0045 0.0074 0.0071
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0016 0.0004 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.013 0.0273 0.0271
Onchocerca volvulus 0.0109 0.0223 0.0221
Trypanosoma brucei aldo/keto reductase, putative 0.0056 0.01 0.2328
Brugia malayi Myb-like DNA-binding domain containing protein 0.0045 0.0074 0.0071
Schistosoma mansoni ran 0.0019 0.0012 0.0009
Echinococcus granulosus tyrosine protein kinase csk 0.0016 0.0004 0.0001
Echinococcus granulosus lamin 0.0026 0.0029 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0058 0.0339
Leishmania major 4-coumarate:coa ligase-like protein 0.002 0.0014 0.027
Echinococcus granulosus TRP transient receptor potential channel 0.0077 0.0148 0.0145
Mycobacterium ulcerans oxidoreductase 0.0195 0.0428 1
Brugia malayi Protein kinase domain containing protein 0.0016 0.0004 0.0002
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0056 0.01 0.0573
Echinococcus granulosus GTP binding nuclear protein Ran 0.0019 0.0012 0.0009
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus multilocularis lamin dm0 0.0026 0.0029 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0017 0.0014
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0038 0.0218
Entamoeba histolytica hypothetical protein 0.0033 0.0043 0.0956
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.028 0.0628 0.0626
Schistosoma mansoni hypothetical protein 0.0058 0.0103 0.01
Loa Loa (eye worm) beta-lactamase 0.0039 0.0058 0.0056
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0038 0.0218
Echinococcus multilocularis tyrosine protein kinase Srms 0.0016 0.0004 0.0001
Echinococcus multilocularis kinase suppressor of Ras 1 0.0016 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.4235 1 1
Loa Loa (eye worm) zinc finger protein 0.0303 0.0684 0.0682
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0195 0.0192
Trichomonas vaginalis aldo-keto reductase, putative 0.0195 0.0428 1
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.084
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0016 0.0004 0.0001
Schistosoma mansoni hypothetical protein 0.0058 0.0103 0.01
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.036
Loa Loa (eye worm) doublecortin family protein 0.0016 0.0003 0.0001
Onchocerca volvulus 0.0016 0.0004 0.0002
Brugia malayi nuclear receptor NHR-88 0.0022 0.0017 0.0014
Schistosoma mansoni hypothetical protein 0.0018 0.0009 0.0006
Echinococcus granulosus Immunoglobulin subtype 0.0058 0.0103 0.01
Onchocerca volvulus 0.0039 0.0058 0.0056
Loa Loa (eye worm) norepinephrine transporter 0.4235 1 1
Brugia malayi Importin beta-1 subunit 0.0026 0.0028 0.0025
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0195 0.0428 0.0425
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0031 0.004 0.0719
Loa Loa (eye worm) hypothetical protein 0.4235 1 1
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0058 0.1049
Brugia malayi bone morphogenetic protein type 1 receptor 0.0016 0.0004 0.0002
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0104 0.0211 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Entamoeba histolytica acyl-CoA synthetase, putative 0.002 0.0014 0.027
Loa Loa (eye worm) hypothetical protein 0.0058 0.0103 0.0101
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0038 0.0218
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0002
Leishmania major importin beta-1 subunit, putative 0.0021 0.0016 0.0318
Schistosoma mansoni hypothetical protein 0.0252 0.0564 0.0561
Loa Loa (eye worm) TK protein kinase 0.0016 0.0004 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0004 0.0036
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0016 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0195 0.0428 0.0426
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Echinococcus multilocularis activin receptor type 0.0016 0.0004 0.0001
Schistosoma mansoni sodium/chloride dependent transporter 0.4235 1 1
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0019 0.0012 0.0268
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0031 0.004 0.0895
Echinococcus granulosus tumor protein p63 0.0683 0.1585 0.1582
Entamoeba histolytica protein kinase, putative 0.0016 0.0004 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.084
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0015 0.036
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0119 0.0116
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Schistosoma mansoni ran 0.0019 0.0012 0.0009
Echinococcus multilocularis integrin linked protein kinase 0.0016 0.0004 0.0001
Entamoeba histolytica hypothetical protein 0.0033 0.0043 0.0956
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0195 0.0192
Brugia malayi Furin-like cysteine rich region family protein 0.0016 0.0004 0.0002
Echinococcus multilocularis FL cytokine receptor 0.0016 0.0004 0.0001
Echinococcus granulosus tyrosine protein kinase Src42A 0.0016 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0016 0.0004 0.0036
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.0065 0.1459
Echinococcus multilocularis hemicentin 1 0.0104 0.0211 0.0208
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0178 0.0388 0.0386
Brugia malayi Immunoglobulin I-set domain containing protein 0.0104 0.0211 0.0208
Schistosoma mansoni protein kinase 0.0016 0.0004 0.0001
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0104 0.0211 0.0209
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0019 0.0012 0.0057
Echinococcus granulosus twitchin 0.0223 0.0495 0.0493
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Entamoeba histolytica ankyrin repeat protein 0.0016 0.0004 0.0036
Onchocerca volvulus 0.0016 0.0004 0.0002
Trichomonas vaginalis aldo-keto reductase, putative 0.0195 0.0428 1
Leishmania major protein kinase, putative 0.0016 0.0004 0.0036
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0004 0.0002
Onchocerca volvulus 0.4235 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0004 0.0036
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.0065 0.1459
Loa Loa (eye worm) hypothetical protein 0.0058 0.0103 0.0101
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Schistosoma mansoni tyrosine kinase 0.0016 0.0004 0.0001
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0102 0.0589
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0719 0.1669 1
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0004 0.0002
Echinococcus granulosus tyrosine kinase 0.0016 0.0004 0.0001
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0017 0.0014
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0104 0.0211 0.0208
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.036

Activities

Activity type Activity value Assay description Source Reference
Agonism (functional) = 25 % Percent of effective dose for [3H]-estradiol against proliferation of MCF-7 cells. ChEMBL. 2769681
Agonism (functional) = 25 % Agonistic activity in MCF-7 cell proliferation. ChEMBL. 1738150
Agonism (functional) = 25 % Percent of effective dose for [3H]-estradiol against proliferation of MCF-7 cells. ChEMBL. 2769681
Agonism (functional) = 25 % Agonistic activity in MCF-7 cell proliferation. ChEMBL. 1738150
EC50 (functional) = 0.19 nM Effective dose for [3H]- estradiol against proliferation of MCF-7 cells ChEMBL. 2769681
EC50 (functional) = 0.19 nM Effective dose for [3H]- estradiol against proliferation of MCF-7 cells ChEMBL. 2769681
IC30 (functional) 0 uM Inhibition of proliferation of MCF-7 cells in presence of 10e-6 M concentration of [3H]- estradiol (E2); nm = not measuable ChEMBL. 2769681
IC30 (functional) = 6.8 uM Inhibitory activity against proliferation of BT-20 cells in presence of TPE at 10e-5 M concentration. ChEMBL. 2769681
IC30 (functional) = 6.8 uM Inhibitory activity against proliferation of BT-20 cells in presence of TPE at 10e-5 M concentration. ChEMBL. 2769681
IC50 (functional) = 34 nM In vitro inhibition of MCF-7 cell proliferation compared to 0.1 nM [3H]-estradiol. ChEMBL. 2769681
IC50 (functional) = 34 nM In vitro inhibition of MCF-7 cell proliferation compared to 0.1 nM [3H]-estradiol. ChEMBL. 2769681
Inhibition (functional) = 13 % Percent of inhibitory activity against proliferation of MCF-7 cells in presence of 10e-6 M concentration of [3H]-estradiol (E2). ChEMBL. 2769681
Inhibition (functional) = 13 % Cytostastic activity against MCF-7 cell proliferation. ChEMBL. 1738150
Inhibition (functional) = 13 % Percent of inhibitory activity against proliferation of MCF-7 cells in presence of 10e-6 M concentration of [3H]-estradiol (E2). ChEMBL. 2769681
Inhibition (functional) = 13 % Cytostastic activity against MCF-7 cell proliferation. ChEMBL. 1738150
Inhibition (functional) = 39 % Percent of inhibitory activity against proliferation of BT-20 cells in presence of TPE at 10e-5 M concentration. ChEMBL. 2769681
Inhibition (functional) = 39 % Percent of inhibitory activity against proliferation of BT-20 cells in presence of TPE at 10e-5 M concentration. ChEMBL. 2769681
Inhibition (functional) = 86 % Percent of inhibitory activity versus 0.1 nm [3H]-estradiol against proliferation of MCF-7 cells. ChEMBL. 2769681
Inhibition (functional) = 86 % Percent of inhibitory activity versus 0.1 nm [3H]-estradiol against proliferation of MCF-7 cells. ChEMBL. 2769681
Inhibition (binding) = 100 % Percent stimulation or inhibition of protein kinase C III activity for phosphatidylserine (PS) in the presence of [Ca2+]. ChEMBL. 1738150
Inhibition (binding) = 100 % Percent stimulation or inhibition of protein kinase C with [Ca2+] for phosphatidylserine (PS) ChEMBL. 1738150
Inhibition (binding) = 100 % Percent stimulation or inhibition of protein kinase C with [Ca2+] for phosphatidylserine and diolein(PS+DO) ChEMBL. 1738150
Inhibition (binding) = 100 % Percent stimulation or inhibition of protein kinase C III activity for phosphatidylserine (PS) in the presence of [Ca2+]. ChEMBL. 1738150
Inhibition (binding) = 100 % Percent stimulation or inhibition of protein kinase C with [Ca2+] for phosphatidylserine (PS) ChEMBL. 1738150
Inhibition (binding) = 100 % Percent stimulation or inhibition of protein kinase C with [Ca2+] for phosphatidylserine and diolein(PS+DO) ChEMBL. 1738150
RBA (binding) = 17 % Relative binding affinity was measured on calf uterus estrogen receptor after 5 hr at 25C. ChEMBL. 1738150
RBA (binding) = 17 % Relative binding affinity was measured on calf uterus estrogen receptor after 5 hr at 25C. ChEMBL. 1738150
RBA1 (binding) = 25 Relative binding affinity against estrogen receptor in calf uterus cytosol using [3H]-E2 as radioligand, incubated at 2 hours at 0 degree centigrade. ChEMBL. 2769681
RBA2 (binding) = 17 Relative binding affinity against estrogen receptor in calf uterus cytosol using [3H]-E2 as radioligand, incubated at 5 hours at 25 degree centigrade. ChEMBL. 2769681
Selectivity (binding) = 0.68 Selectivity for relative binding affinity against estrogen receptor at 2 hrs and 5 hr in calf uterus cytosol ChEMBL. 2769681

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 2769681

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

2 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.