Detailed information for compound 181474

Basic information

Technical information
  • TDR Targets ID: 181474
  • Name: N'-[(3,4-dichlorophenyl)methyl]-N,N'-dimethyl -N-(3-pyrrolidin-1-ylpropyl)ethane-1,2-diamin e
  • MW: 358.349 | Formula: C18H29Cl2N3
  • H donors: 0 H acceptors: 0 LogP: 3.93 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCN(Cc1ccc(c(c1)Cl)Cl)C)CCCN1CCCC1
  • InChi: 1S/C18H29Cl2N3/c1-21(8-5-11-23-9-3-4-10-23)12-13-22(2)15-16-6-7-17(19)18(20)14-16/h6-7,14H,3-5,8-13,15H2,1-2H3
  • InChiKey: GSQAIYDFJXVNLC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N'-[(3,4-dichlorophenyl)methyl]-N,N'-dimethyl-N-[3-(1-pyrrolidinyl)propyl]ethane-1,2-diamine
  • (3,4-dichlorobenzyl)-methyl-[2-[methyl(3-pyrrolidinopropyl)amino]ethyl]amine
  • N'-[(3,4-dichlorophenyl)methyl]-N,N'-dimethyl-N-(3-1-pyrrolidinylpropyl)ethane-1,2-diamine
  • 2-[(3,4-dichlorobenzyl)-methyl-amino]ethyl-methyl-(3-pyrrolidin-1-ylpropyl)amine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens sigma non-opioid intracellular receptor 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania donovani C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131051 All targets in OG5_131051
Candida albicans sterol C8-C7 isomerase Get druggable targets OG5_131051 All targets in OG5_131051
Trypanosoma congolense C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Leishmania mexicana C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Trypanosoma cruzi C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Leishmania braziliensis C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Trypanosoma brucei C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Candida albicans sterol C8-C7 isomerase Get druggable targets OG5_131051 All targets in OG5_131051
Leishmania major C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Leishmania infantum C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131051 All targets in OG5_131051
Trypanosoma brucei gambiense C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Brugia malayi ERG2 and Sigma1 receptor like protein Get druggable targets OG5_131051 All targets in OG5_131051
Trypanosoma congolense C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica cysteine protease, putative 0.0005 0.0005 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Trypanosoma brucei calpain-like protein, putative 0.0011 0.0026 0.0088
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0011 0.0025 0.0108
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0007 0.0011 0.0036
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0005 0.0006 0.0021
Echinococcus granulosus histone deacetylase 7 0.0075 0.0259 0.1157
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0013 0.0032 0.003
Trypanosoma brucei calpain-like protein, putative 0.0011 0.0026 0.0088
Trichomonas vaginalis DNA helicase recq, putative 0.0008 0.0016 0.0138
Entamoeba histolytica cysteine proteinase 2 0.0005 0.0005 0.0059
Plasmodium vivax multidomain scavenger receptor, putative 0.0005 0.0005 0.0159
Schistosoma mansoni gliotactin 0.0315 0.1127 0.5058
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0014 0.0035 0.0033
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0004 0.0001 0.0002
Toxoplasma gondii PHD-finger domain-containing protein 0.0004 0.0001 0.0045
Leishmania major cathepsin L-like protease 0.0023 0.007 0.0241
Loa Loa (eye worm) cysteine protease 0.0011 0.0024 0.008
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0005 0.0004 0.003
Loa Loa (eye worm) histone deacetylase 1 0.006 0.0201 0.0695
Echinococcus granulosus lipoxygenase domain containing protein 0.0005 0.0005 0.0018
Mycobacterium ulcerans short-chain dehydrogenase 0.0005 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0083
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0099 0.0873
Loa Loa (eye worm) hypothetical protein 0.0006 0.0006 0.0017
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0005 0.0005 0.0024
Toxoplasma gondii type I fatty acid synthase, putative 0.0011 0.0025 0.0982
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0013 0.0032 0.0106
Echinococcus granulosus nicotinamide phosphoribosyltransferase 0.0252 0.0898 0.4028
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0011 0.0026 0.0088
Mycobacterium leprae Probable two component sensor kinase MprB 0.0012 0.003 0.0063
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0315 0.1127 0.5058
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.0648 0.5742
Echinococcus granulosus transcription factor Dp 1 0.001 0.0023 0.01
Brugia malayi Steroid receptor seven-up type 2 0.0005 0.0006 0.0016
Echinococcus granulosus chromobox protein 1 0.0031 0.0099 0.0441
Plasmodium falciparum cysteine proteinase falcipain 3 0.0011 0.0024 0.0899
Leishmania major 4-coumarate:coa ligase-like protein 0.0015 0.0039 0.0133
Plasmodium falciparum plasmepsin I 0.0023 0.0069 0.2647
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0011 0.0093
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0012 0.003 0.0028
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0005 0.0004 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0005 0.0004 0.0126
Loa Loa (eye worm) hypothetical protein 0.0315 0.1127 0.3907
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0015 0.0039 0.2992
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0011 0.0027 0.0089
Schistosoma mansoni rab6-interacting 0.0005 0.0005 0.0023
Leishmania major p450 reductase, putative 0.0013 0.0034 0.0116
Schistosoma mansoni polycystin 1-related 0.0005 0.0005 0.0023
Trichomonas vaginalis receptor histidine kinase, putative 0.0016 0.0043 0.0371
Schistosoma mansoni chromobox protein 0.0005 0.0004 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.007 0.0241
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0043
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0015 0.0039 0.1461
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0023 0.0069 0.0237
Trypanosoma cruzi cysteine peptidase, putative 0.0005 0.0005 0.0016
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0059 0.0199 0.089
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0026 0.0087
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0037 0.0119 0.041
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0053 0.0178 0.08
Schistosoma mansoni histone deacetylase hda2 0.0077 0.0263 0.1182
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0007 0.0012 0.0029
Trypanosoma brucei calpain-like protein, putative 0.0011 0.0026 0.0088
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0037 0.0119 0.041
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0008 0.0013 0.0515
Brugia malayi Eukaryotic aspartyl protease family protein 0.0005 0.0005 0.0015
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0008 0.0013 0.006
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0089 0.0309 0.0308
Schistosoma mansoni tyrosine kinase 0.006 0.0204 0.0914
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0315 0.1127 0.1126
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0013 0.0034 0.0033
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0024 0.0073 0.0642
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0315 0.1127 0.5058
Brugia malayi AF-10 protein 0.0004 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0006 0.0009 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0053 0.0178 0.0615
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0025 0.0078 0.0267
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0013 0.0032 0.0068
Trypanosoma cruzi cruzipain precursor, putative 0.0023 0.007 0.0241
Echinococcus granulosus acetylcholinesterase 0.0315 0.1127 0.5056
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0018 0.0052 0.0051
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0052 0.0173 0.0773
Brugia malayi hypothetical protein 0.0005 0.0005 0.0015
Brugia malayi eukaryotic initiation factor 4A 0.0018 0.0053 0.0179
Onchocerca volvulus 0.0013 0.0034 0.0294
Echinococcus granulosus histone deacetylase 6 0.0075 0.0259 0.1157
Entamoeba histolytica cysteine protease, putative 0.0005 0.0005 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.007 0.0241
Schistosoma mansoni fkbp-rapamycin associated protein 0.0006 0.0009 0.0039
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0007 0.0056
Leishmania major hypothetical protein, conserved 0.0005 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0022 0.0067 0.0229
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0005 0.0005 0.0024
Echinococcus granulosus cysteine protease 0.0005 0.0005 0.002
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0005 0.0005 0.0004
Plasmodium vivax hypothetical protein, conserved 0.0005 0.0004 0.0128
Onchocerca volvulus 0.0011 0.0024 0.0202
Schistosoma mansoni cathepsin D (A01 family) 0.0068 0.0232 0.104
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0078
Loa Loa (eye worm) hypothetical protein 0.0032 0.0101 0.0348
Echinococcus granulosus RUN 0.0005 0.0005 0.0018
Entamoeba histolytica cysteine protease, putative 0.0005 0.0005 0.0059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0011 0.0024 0.0207
Echinococcus multilocularis vesicular acetylcholine transporter 0.0214 0.0759 0.2003
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0013 0.0032 0.0068
Echinococcus multilocularis microtubule associated protein 2 0.062 0.2228 0.5887
Brugia malayi calpain 5 0.0008 0.0014 0.0046
Brugia malayi Glycosyl hydrolases family 31 protein 0.0006 0.0008 0.0024
Echinococcus multilocularis bloom syndrome protein 0.0011 0.0026 0.0067
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0107 0.0372 0.1287
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0012 0.003 0.0028
Loa Loa (eye worm) steroid hormone receptor 0.0005 0.0006 0.0016
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0013 0.0032 0.0107
Toxoplasma gondii isocitrate dehydrogenase 0.0007 0.0012 0.0459
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Trypanosoma cruzi kinesin, putative 0.0008 0.0014 0.0046
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0005 0.0005 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0005 0.0006 0.0016
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0004 0.0001 0.0017
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0007 0.0012 0.0029
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0008 0.0013 0.0043
Trypanosoma cruzi kinesin, putative 0.0008 0.0014 0.0046
Mycobacterium tuberculosis Probable esterase LipL 0.0014 0.0035 0.0033
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0015 0.0039 0.0038
Echinococcus granulosus calpain A 0.0032 0.0102 0.0454
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0005 0.0006 0.0016
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0012 0.003 0.2221
Echinococcus granulosus cathepsin l1 0.0011 0.0024 0.0104
Schistosoma mansoni calpain-7 (C02 family) 0.0011 0.0026 0.0118
Trypanosoma cruzi histone deacetylase 1, putative 0.006 0.0201 0.0695
Loa Loa (eye worm) heterochromatin protein 1 0.0031 0.0099 0.0341
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0049 0.043
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0013 0.0034 0.0116
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0005 0.0004 0.0003
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0011 0.0027 0.0089
Treponema pallidum fructose-bisphosphate aldolase 0.0183 0.0648 0.144
Mycobacterium ulcerans hypothetical protein 0.0014 0.0035 0.0033
Echinococcus multilocularis GPCR, family 2 0.0034 0.0108 0.0283
Echinococcus granulosus chromobox protein 1 0.0031 0.0099 0.0441
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0011 0.0026 0.0088
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0009 0.002 0.0019
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0035 0.0116
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0005 0.0005 0.0024
Onchocerca volvulus 0.0005 0.0006 0.0037
Loa Loa (eye worm) hypothetical protein 0.0045 0.0147 0.0508
Brugia malayi histone deacetylase 11 0.0031 0.0097 0.0333
Schistosoma mansoni chromobox protein 0.0031 0.0099 0.0445
Entamoeba histolytica cysteine protease, putative 0.0005 0.0005 0.0059
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0037 0.0119 0.0535
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0018 0.0051 0.0172
Echinococcus multilocularis Chromobox protein 3 0.0005 0.0004 0.0009
Brugia malayi Protein kinase domain containing protein 0.0135 0.0474 0.1641
Entamoeba histolytica type A flavoprotein, putative 0.0005 0.0004 0.0046
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0004 0.0001 0.0002
Schistosoma mansoni histone deacetylase 1 2 3 0.0031 0.0097 0.0435
Loa Loa (eye worm) doublecortin family protein 0.0005 0.0005 0.0014
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0018 0.0053 0.0179
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0059 0.0199 0.0687
Schistosoma mansoni protein phosphatase 2C 0.0004 0.0001 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0011 0.0024 0.0207
Echinococcus granulosus cathepsin L 0.0005 0.0005 0.002
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0011 0.0027 0.0286
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0036
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0005 0.0006 0.0021
Echinococcus granulosus epidermal growth factor receptor 0.0061 0.0208 0.0928
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0011 0.0025 0.0063
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0018 0.0051 0.0172
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0005 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0011 0.0026 0.0086
Schistosoma mansoni thyroid hormone receptor 0.0005 0.0006 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0026 0.0087
Echinococcus multilocularis lamin dm0 0.0022 0.0067 0.0175
Echinococcus granulosus histone deacetylase 6 0.0077 0.0263 0.1178
Loa Loa (eye worm) hypothetical protein 0.0315 0.1127 0.3907
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0037 0.0119 0.041
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0135 0.0474 0.125
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0032 0.0101 0.0455
Echinococcus multilocularis epidermal growth factor receptor 0.0061 0.0208 0.0546
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0094 0.3625
Loa Loa (eye worm) pre-B cell enhancing factor 0.0252 0.0898 0.3113
Onchocerca volvulus Histone deacetylase 10 homolog 0.0031 0.0097 0.0848
Echinococcus multilocularis epidermal growth factor receptor 0.0061 0.0208 0.0546
Plasmodium vivax plasmepsin V, putative 0.0005 0.0005 0.0171
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0005 0.0004 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Plasmodium falciparum phd finger protein, putative 0.0013 0.0033 0.1249
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0011 0.0027 0.0068
Brugia malayi CXXC zinc finger family protein 0.0008 0.0014 0.0045
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.001 0.0023 0.0022
Echinococcus multilocularis L aminoadipate semialdehyde 0.0052 0.0174 0.0457
Brugia malayi histone deacetylase 1 (HD1) 0.006 0.0201 0.0695
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.0648 0.5742
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.001 0.0023 0.0049
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0204 0.0203
Loa Loa (eye worm) hypothetical protein 0.0315 0.1127 0.3907
Brugia malayi jmjC domain containing protein 0.0016 0.0045 0.0152
Toxoplasma gondii exonuclease III APE 0.0005 0.0004 0.0161
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0059 0.0199 0.0893
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0007 0.0012 0.0049
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0039 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0005 0.0006 0.0016
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0018 0.005 0.017
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.001 0.0023 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Brugia malayi jmjC domain containing protein 0.0043 0.0141 0.0487
Schistosoma mansoni hypothetical protein 0.0067 0.0227 0.1017
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0011 0.0026 0.0088
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0315 0.1127 0.5058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.001 0.0023 0.0049
Loa Loa (eye worm) phosphatidylinositol 3 0.0011 0.0027 0.0089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.007 0.0241
Echinococcus granulosus PHD finger protein rhinoceros 0.0013 0.0033 0.0144
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0008 0.0013 0.0515
Schistosoma mansoni tyrosine kinase 0.006 0.0204 0.0914
Schistosoma mansoni hypothetical protein 0.0034 0.0108 0.0484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0011 0.0024 0.0899
Loa Loa (eye worm) CHromoDomain protein family member 0.0006 0.0006 0.0017
Trichomonas vaginalis histone deacetylase, putative 0.006 0.0201 0.178
Echinococcus multilocularis geminin 0.0154 0.0543 0.1433
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0043
Toxoplasma gondii cathepsin CPL 0.0011 0.0024 0.0932
Echinococcus multilocularis cysteine protease 0.0011 0.0024 0.0061
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0011 0.0024 0.0207
Mycobacterium ulcerans DNA polymerase IV 0.0011 0.0026 0.0025
Treponema pallidum nicotinate phosphoribosyltransferase 0.0047 0.0155 0.0337
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0067 0.0227 0.1013
Onchocerca volvulus 0.0014 0.0035 0.0294
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0008 0.0013 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0005 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0008 0.0016 0.0053
Toxoplasma gondii histone deacetylase HDAC4 0.0031 0.0097 0.3746
Plasmodium falciparum histone deacetylase 1 0.006 0.0201 0.7779
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0043
Plasmodium vivax hypothetical protein, conserved 0.0005 0.0005 0.015
Plasmodium vivax amine transporter, putative 0.0008 0.0013 0.048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0005 0.0005 0.0004
Schistosoma mansoni integrin beta subunit 0.0022 0.0064 0.0285
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0037 0.0119 0.0535
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0006 0.0009 0.007
Entamoeba histolytica cysteine protease, putative 0.0005 0.0005 0.0059
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0006 0.0009 0.0017
Echinococcus multilocularis musashi 0.0022 0.0067 0.0175
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0005 0.0003 0.0011
Mycobacterium tuberculosis Polyketide synthase Pks12 0.001 0.0023 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0005 0.0006 0.0016
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0023 0.0069 0.018
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0032 0.0102 0.0453
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0024 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0006 0.0009 0.007
Brugia malayi calpain family protein 1 0.003 0.0094 0.0321
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0005 0.0004 0.0009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0005 0.0004 0.0011
Trypanosoma cruzi histone deacetylase, putative 0.0075 0.0259 0.0894
Schistosoma mansoni transcription factor LCR-F1 0.0067 0.0227 0.1017
Onchocerca volvulus Cathepsin L homolog 0.0011 0.0024 0.0202
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0005 0.0005 0.0014
Onchocerca volvulus 0.0015 0.0039 0.0337
Plasmodium vivax aspartyl proteinase, putative 0.0005 0.0005 0.0171
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0011 0.0026 0.0088
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0012 0.0029 0.0248
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0011 0.0026 0.0024
Leishmania major cathepsin L-like protease 0.0011 0.0024 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0005 0.0006 0.0016
Trichomonas vaginalis chromobox protein, putative 0.0005 0.0004 0.003
Trypanosoma brucei histone deacetylase 2 0.0031 0.0097 0.0333
Brugia malayi flavodoxin family protein 0.0005 0.0004 0.0011
Leishmania major cathepsin L-like protease 0.0011 0.0024 0.008
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0046 0.0398
Schistosoma mansoni vesicular acetylcholine transporter 0.0214 0.0759 0.3405
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0736 0.2549
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0005 0.0005 0.0015
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0006 0.0009 0.0008
Schistosoma mansoni rab6-interacting 0.0005 0.0005 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0008 0.0016 0.0053
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0011 0.0027 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0031 0.0265
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0006 0.0008 0.0059
Echinococcus multilocularis carboxylesterase 5A 0.0315 0.1127 0.2977
Mycobacterium tuberculosis Probable oxidoreductase 0.0208 0.0737 0.0736
Loa Loa (eye worm) hypothetical protein 0.0005 0.0005 0.0016
Entamoeba histolytica calpain large subunit domain III containing protein 0.0008 0.0014 0.0152
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0204 0.0705
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0005 0.0006 0.0025
Loa Loa (eye worm) acetyltransferase 0.0039 0.0128 0.0442
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0027
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0011 0.0027 0.009
Brugia malayi Pre-SET motif family protein 0.003 0.0094 0.0322
Trichomonas vaginalis receptor histidine kinase, putative 0.0016 0.0043 0.0371
Mycobacterium ulcerans DNA polymerase IV 0.0011 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0011
Echinococcus granulosus bloom syndrome protein 0.0011 0.0026 0.0113
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0007 0.0012 0.0029
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0204 0.0203
Loa Loa (eye worm) hypothetical protein 0.0045 0.0149 0.0513
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0036
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0039 0.0133
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0037 0.0119 0.041
Schistosoma mansoni sodium/chloride dependent transporter 0.0008 0.0013 0.006
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.0252 0.0898 0.4031
Loa Loa (eye worm) CXXC zinc finger family protein 0.0008 0.0014 0.0045
Toxoplasma gondii PHD-finger domain-containing protein 0.0013 0.0033 0.1281
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0005 0.0006 0.0016
Trichomonas vaginalis sensor histidine kinase, putative 0.0016 0.0043 0.0371
Onchocerca volvulus 0.0008 0.0014 0.0111
Entamoeba histolytica cysteine protease, putative 0.0005 0.0005 0.0059
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0005 0.0005 0.0004
Brugia malayi nuclear hormone receptor 0.0005 0.0006 0.0016
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0019 0.0053 0.0179
Echinococcus multilocularis muscleblind protein 0.0078 0.0269 0.0708
Brugia malayi beta-lactamase family protein 0.0014 0.0035 0.0116
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0007 0.0011 0.001
Brugia malayi AMP-binding enzyme family protein 0.0013 0.0034 0.0116
Brugia malayi F/Y-rich N-terminus family protein 0.0008 0.0014 0.0044
Leishmania major eukaryotic initiation factor 4a, putative 0.0018 0.0053 0.0179
Schistosoma mansoni phd/f-box containing protein 0.0004 0.0001 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.0208 0.0737 0.0736
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.001 0.0021 0.0044
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0015 0.0039 0.1461
Brugia malayi Pepsin A precursor 0.0005 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0031 0.0097 0.0333
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0018 0.0052 0.0051
Echinococcus multilocularis integrin beta 2 0.0027 0.0084 0.0219
Brugia malayi ERG2 and Sigma1 receptor like protein 0.08 0.2883 1
Toxoplasma gondii isocitrate dehydrogenase 0.0007 0.0012 0.0459
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0004 0.0001 0.0054
Entamoeba histolytica nicotinate phosphoribosyltransferase, putative 0.0047 0.0155 0.1665
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0005 0.0004 0.0011
Echinococcus granulosus carboxylesterase 5A 0.0315 0.1127 0.5056
Brugia malayi Histone deacetylase 1 0.006 0.0201 0.0695
Onchocerca volvulus 0.0008 0.0013 0.0106
Loa Loa (eye worm) acetylcholinesterase 1 0.0315 0.1127 0.3907
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.0648 0.5742
Echinococcus multilocularis histone deacetylase 7 0.0075 0.0259 0.0681
Echinococcus multilocularis neuroligin 0.0315 0.1127 0.2977
Loa Loa (eye worm) hypothetical protein 0.0006 0.0008 0.0024
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0078
Brugia malayi Pre-SET motif family protein 0.0207 0.0736 0.2549
Echinococcus granulosus histone deacetylase 0.0075 0.0259 0.1157
Brugia malayi AMP-binding enzyme family protein 0.0004 0.0001 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0011 0.0087
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0007 0.0012 0.0038
Trypanosoma cruzi DNA polymerase kappa, putative 0.0011 0.0026 0.0087
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0024 0.0108
Plasmodium falciparum plasmepsin VIII, putative 0.0005 0.0005 0.0171
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0204 0.7901
Trichomonas vaginalis alpha-glucosidase, putative 0.0006 0.0008 0.0063
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0005 0.0004 0.0011
Brugia malayi Cathepsin L-like precursor 0.0011 0.0024 0.008
Plasmodium falciparum heterochromatin protein 1 0.0005 0.0004 0.0126
Onchocerca volvulus 0.0315 0.1127 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.018
Loa Loa (eye worm) fatty acid synthase 0.001 0.0021 0.0068
Loa Loa (eye worm) hypothetical protein 0.0011 0.0026 0.0086
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0007 0.0012 0.0053
Trypanosoma brucei nicotinate phosphoribosyltransferase, putative 0.0047 0.0155 0.0534
Echinococcus multilocularis muscleblind protein 1 0.0078 0.0269 0.0708
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0004 0.0001 0.0054
Schistosoma mansoni survival motor neuron protein 0.0018 0.005 0.0225
Trichomonas vaginalis alpha-glucosidase, putative 0.0006 0.0008 0.0063
Echinococcus multilocularis BC026374 protein (S09 family) 0.0315 0.1127 0.2977
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0018 0.0052 0.0051
Brugia malayi aspartic protease BmAsp-1, identical 0.0005 0.0005 0.0015
Leishmania major eukaryotic initiation factor 4a, putative 0.0018 0.0053 0.0179
Brugia malayi Carboxylesterase family protein 0.0315 0.1127 0.3907
Echinococcus multilocularis FTZ F1 alpha 0.0005 0.0006 0.0012
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0005 0.0006 0.0021
Plasmodium falciparum LCCL domain-containing protein 0.0005 0.0005 0.0159
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0059 0.0199 0.0893
Trichomonas vaginalis histone deacetylase, putative 0.006 0.0201 0.178
Plasmodium falciparum transporter, putative 0.0008 0.0013 0.048
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0011 0.0026 0.0224
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0016 0.0042 0.0188
Schistosoma mansoni hypothetical protein 0.0073 0.025 0.1121
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0016
Leishmania major phosphopantetheinyl transferase-like protein 0.0015 0.0039 0.0131
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0013 0.0032 0.0274
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0011 0.0024 0.0207
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0037 0.0119 0.1282
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0016
Echinococcus multilocularis jumonji domain containing protein 0.0018 0.0052 0.0134
Onchocerca volvulus Fatty acid synthase homolog 0.0018 0.0049 0.0426
Trypanosoma brucei DNA polymerase kappa, putative 0.0005 0.0002 0.0003
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0024 0.0073 0.0642
Echinococcus multilocularis dna polymerase kappa 0.0011 0.0026 0.0066
Loa Loa (eye worm) hypothetical protein 0.0024 0.0073 0.0251
Echinococcus granulosus insulin receptor 0.0135 0.0474 0.2123
Loa Loa (eye worm) hypothetical protein 0.0011 0.0026 0.0086
Entamoeba histolytica cysteine proteinase, putative 0.0005 0.0005 0.0059
Echinococcus granulosus calpain 5 0.0011 0.0026 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Plasmodium vivax acetyl-CoA synthetase, putative 0.0004 0.0001 0.0017
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0067 0.0227 0.0596
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.003 0.0094 0.042
Brugia malayi histone deacetylase 3 (HD3) 0.006 0.0201 0.0695
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Brugia malayi Doublecortin family protein 0.0005 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0015 0.0039 0.0133
Echinococcus multilocularis serotonin transporter 0.0045 0.0149 0.0391
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0007 0.0012 0.0038
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0015 0.0039 0.1492
Loa Loa (eye worm) hypothetical protein 0.0018 0.0049 0.0168
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0005 0.0006 0.0016
Loa Loa (eye worm) histone deacetylase 7A 0.0075 0.0259 0.0894
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0013 0.0034 0.0088
Schistosoma mansoni cathepsin F (C01 family) 0.0007 0.0011 0.0051
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0214 0.0759 0.6728
Schistosoma mansoni hypothetical protein 0.0154 0.0543 0.2438
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0108 0.048
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0018 0.0053 0.0136
Mycobacterium ulcerans acyl-CoA synthetase 0.0005 0.0005 0.0004
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0008 0.0014 0.0058
Schistosoma mansoni cytochrome P450 reductase 0.0013 0.0034 0.0154
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0005 0.0006 0.0025
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0037 0.0119 0.4592
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0009
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0024 0.0073 0.1072
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0011 0.0027 0.009
Plasmodium vivax aspartyl proteinase, putative 0.0023 0.0069 0.2647
Loa Loa (eye worm) hypothetical protein 0.003 0.0094 0.0322
Loa Loa (eye worm) hypothetical protein 0.0013 0.0033 0.0112
Brugia malayi exodeoxyribonuclease III family protein 0.0005 0.0004 0.0011
Mycobacterium leprae conserved hypothetical protein 0.0014 0.0035 0.0074
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0011 0.0027 0.009
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0023 0.0069 0.0306
Loa Loa (eye worm) calpain family protein 1 0.0022 0.0065 0.0223
Brugia malayi acetyltransferase, GNAT family protein 0.0039 0.0128 0.0442
Entamoeba histolytica cysteine proteinase, putative 0.0005 0.0005 0.0059
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0017 0.0046 0.1767
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0046 0.0398
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0037 0.0119 0.0535
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0018 0.0053 0.0236
Toxoplasma gondii aspartyl protease ASP1 0.0023 0.0069 0.2674
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0011 0.0027 0.0115
Loa Loa (eye worm) PHD-finger family protein 0.0013 0.0033 0.0112
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0005 0.0004 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0035 0.0116
Loa Loa (eye worm) integrin beta-2 0.0037 0.0118 0.0406
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0011 0.0027 0.0089
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0004 0.0001 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0026 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0004 0.003
Loa Loa (eye worm) aspartyl protease 6 0.0005 0.0005 0.0015
Trichomonas vaginalis histone deacetylase, putative 0.006 0.0201 0.178
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.025 0.0863
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0018 0.0053 0.0232
Brugia malayi Carboxylesterase family protein 0.0315 0.1127 0.3907
Trichomonas vaginalis PIKK family atypical protein kinase 0.0006 0.0009 0.007
Trichomonas vaginalis maltase-glucoamylase, putative 0.0017 0.0046 0.0398
Mycobacterium leprae conserved hypothetical protein 0.0015 0.0039 0.0083
Echinococcus granulosus epidermal growth factor receptor 0.0061 0.0208 0.0928
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0005 0.0004 0.0011
Trichomonas vaginalis DNA polymerase eta, putative 0.0011 0.0026 0.0224
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0042 0.0142
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0018 0.0051 0.0172
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0005 0.0004 0.003
Brugia malayi FAT domain containing protein 0.0005 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0013 0.0034 0.0116
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0005 0.0006 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0031 0.0265
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0026 0.0087
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0094 0.0421
Trypanosoma brucei oligopeptidase b 0.0013 0.0032 0.0106
Treponema pallidum methylgalactoside ABC transporter, periplasmic galactose-binding protein (mglB-2) 0.124 0.4473 1
Trypanosoma brucei DNA polymerase IV, putative 0.0011 0.0026 0.0087
Toxoplasma gondii propionate-CoA ligase 0.0004 0.0001 0.0054
Trichomonas vaginalis hypothetical protein 0.0005 0.0004 0.003
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0011 0.0024 0.0899
Loa Loa (eye worm) hypothetical protein 0.0011 0.0026 0.0086
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0012 0.0029 0.0098
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0005 0.0005 0.0004
Trypanosoma cruzi histone deacetylase, putative 0.0031 0.0097 0.0333
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0135 0.0474 0.2123
Mycobacterium ulcerans thioesterase 0.0008 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0045 0.0149 0.0513
Onchocerca volvulus 0.0005 0.0004 0.0025
Toxoplasma gondii type I fatty acid synthase, putative 0.0007 0.0011 0.0418
Loa Loa (eye worm) fibroinase 0.0011 0.0024 0.008
Brugia malayi hypothetical protein 0.0005 0.0005 0.0015
Echinococcus multilocularis cpg binding protein 0.0008 0.0016 0.0039
Mycobacterium ulcerans hypothetical protein 0.0015 0.0039 0.0038
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0011 0.0024 0.008
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0024 0.0073 0.0251
Leishmania major 4-coumarate:coa ligase-like protein 0.0015 0.0039 0.0133
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0011 0.0027 0.009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0005 0.0006 0.0021
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0012 0.003 0.1547
Schistosoma mansoni RAR-like nuclear receptor 0.0005 0.0006 0.0025
Trypanosoma cruzi histone deacetylase, putative 0.0075 0.0259 0.0894
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0005 0.0005 0.0041
Schistosoma mansoni tyrosine kinase 0.0061 0.0208 0.0932
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.001 0.0021 0.002
Trichomonas vaginalis histone deacetylase, putative 0.006 0.0201 0.178
Echinococcus multilocularis lysine specific demethylase 5A 0.0016 0.0043 0.0111
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.001 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0065 0.0223
Plasmodium falciparum plasmepsin III 0.0005 0.0005 0.0171
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0014 0.0035 0.0033
Brugia malayi Intermediate filament tail domain containing protein 0.0022 0.0067 0.0229
Loa Loa (eye worm) histone deacetylase 0.0075 0.0259 0.0894
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Trichomonas vaginalis ap endonuclease, putative 0.0005 0.0004 0.0029
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0046 0.0398
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0005 0.0006 0.0012
Onchocerca volvulus 0.0014 0.0035 0.0294
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0016 0.0042 0.0142
Loa Loa (eye worm) hypothetical protein 0.0013 0.0034 0.0115
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0023 0.0069 0.0606
Entamoeba histolytica hypothetical protein 0.0067 0.0227 0.2436
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0034 0.0113
Loa Loa (eye worm) carboxylesterase 0.0315 0.1127 0.3907
Echinococcus granulosus intermediate filament protein 0.0022 0.0067 0.0297
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0018 0.0051 0.0227
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0037 0.0119 0.041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.0648 0.5742
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0005 0.0006 0.0016
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0015 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0107 0.0372 0.1287
Schistosoma mansoni histone deacetylase 4 5 0.0075 0.0259 0.116
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0011 0.0027 0.0089
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0011 0.0087
Leishmania major cathepsin L-like protease 0.0023 0.007 0.0241
Brugia malayi Cathepsin L-like precursor 0.0007 0.0011 0.0036
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0006 0.0006 0.022
Echinococcus multilocularis beta LACTamase domain containing family member 0.0014 0.0035 0.0089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.007 0.0241
Echinococcus granulosus muscleblind protein 0.0078 0.0269 0.1202
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0005 0.0004 0.0011
Echinococcus multilocularis histone deacetylase 6 0.0077 0.0263 0.0693
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0005 0.0005 0.0024
Mycobacterium ulcerans Type I modular polyketide synthase 0.001 0.0021 0.002
Leishmania major oligopeptidase b 0.0013 0.0032 0.0106
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0011 0.0024 0.0207
Schistosoma mansoni hypothetical protein 0.0018 0.005 0.0225
Leishmania major cathepsin L-like protease 0.0011 0.0024 0.008
Trypanosoma brucei histone deacetylase, putative 0.0075 0.0259 0.0894
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0005 0.0005 0.0208
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0006 0.0009 0.0094
Plasmodium vivax histone deacetylase 2, putative 0.0075 0.0259 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0005 0.0006 0.0016
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0004 0.0001 0.0002
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0052 0.0174 0.0781
Loa Loa (eye worm) TK/EGFR protein kinase 0.0061 0.0208 0.0717
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0094 0.0245
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0011 0.0024 0.0207
Loa Loa (eye worm) histone deacetylase 11 0.0031 0.0097 0.0333
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0032 0.0101 0.0348
Schistosoma mansoni lamin 0.0022 0.0067 0.0301
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0007 0.0012 0.0038
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0006 0.0008 0.0024
Mycobacterium ulcerans two component sensor kinase MprB 0.0012 0.003 0.0028
Trichomonas vaginalis maltase-glucoamylase, putative 0.0006 0.0008 0.0063
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0011 0.0027 0.0089
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0037 0.0119 0.0531
Schistosoma mansoni hypothetical protein 0.0034 0.0108 0.0484
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0006 0.0006 0.0017
Echinococcus multilocularis chromobox protein 1 0.0031 0.0099 0.026
Loa Loa (eye worm) glutaminase 2 0.0123 0.0431 0.1492
Loa Loa (eye worm) hypothetical protein 0.0315 0.1127 0.3907
Toxoplasma gondii histone lysine methyltransferase SET1 0.0017 0.0047 0.1805
Onchocerca volvulus Bile acid receptor homolog 0.0005 0.0006 0.0037
Echinococcus granulosus survival motor neuron protein 1 0.0087 0.0302 0.135
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0059 0.0199 0.0893
Giardia lamblia Fructose-bisphosphate aldolase 0.0183 0.0648 1
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0004 0.003
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0024 0.0073 0.0324
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0008 0.0013 0.0055
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0005 0.0004 0.003
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0012 0.003 0.0028
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0037 0.0119 0.1051
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0012 0.003 0.0028
Echinococcus granulosus cathepsin l1 0.0007 0.0011 0.0047
Entamoeba histolytica acyl-CoA synthetase, putative 0.0016 0.0043 0.0461
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0005 0.0004 0.0019
Entamoeba histolytica cysteine protease, putative 0.0005 0.0005 0.0059
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0018 0.0053 0.2032
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0006 0.0025
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0006 0.0009 0.0035
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0011 0.0026 0.0088
Entamoeba histolytica recQ family helicase, putative 0.0008 0.0016 0.0176
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0012 0.0028 0.1034
Schistosoma mansoni histone deacetylase 4 5 0.0075 0.0259 0.116
Brugia malayi Cathepsin L-like precursor 0.0011 0.0024 0.008
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0011 0.0027 0.0068
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0024 0.0073 0.025
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0019 0.0054 0.0468
Onchocerca volvulus 0.0021 0.0063 0.0547
Echinococcus multilocularis cathepsin L 0.0005 0.0005 0.0012
Trichomonas vaginalis chromobox protein, putative 0.0005 0.0004 0.003
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0016
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0011 0.0027 0.0115
Loa Loa (eye worm) hypothetical protein 0.0014 0.0036 0.012
Onchocerca volvulus 0.0043 0.0142 0.1251
Schistosoma mansoni apoptosis regulator bax 0.0052 0.0173 0.0777
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0053 0.0178 0.0469
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0005 0.0004 0.0126
Trypanosoma brucei calpain-like protein, putative 0.0011 0.0026 0.0088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0011 0.0024 0.0207
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0008 0.0013 0.0043
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0004 0.0001 0.0037
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0108 0.0371
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.007 0.0241
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0015 0.004 0.0103
Trichomonas vaginalis Heterochromatin protein, putative 0.0005 0.0004 0.003
Entamoeba histolytica type A flavoprotein, putative 0.0005 0.0004 0.0046
Toxoplasma gondii flavodoxin domain-containing protein 0.0007 0.001 0.0379
Mycobacterium tuberculosis Probable hydrolase 0.0014 0.0035 0.0033
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0012 0.003 0.0028
Trypanosoma cruzi DNA polymerase kappa, putative 0.0011 0.0026 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0011 0.0024 0.0207
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0011 0.0027 0.0089
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0005 0.0005 0.0016
Schistosoma mansoni hypothetical protein 0.0004 0.0001 0.0005
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0015 0.0039 0.2385
Echinococcus granulosus cathepsin l cysteine peptidase 0.0011 0.0024 0.0104
Echinococcus multilocularis nicotinamide phosphoribosyltransferase 0.0252 0.0898 0.2372
Schistosoma mansoni hypothetical protein 0.0154 0.0543 0.2438
Brugia malayi beta-lactamase 0.0014 0.0035 0.0116
Loa Loa (eye worm) hypothetical protein 0.0315 0.1127 0.3907
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0004 0.0001 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0009 0.002 0.0065
Onchocerca volvulus 0.0315 0.1127 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0007 0.0012 0.0029
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0011 0.0024 0.0061
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0116
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0052 0.0174 0.06
Leishmania major cathepsin L-like protease 0.0011 0.0024 0.008
Brugia malayi Pre-B cell enhancing factor precursor 0.0252 0.0898 0.3113
Loa Loa (eye worm) norepinephrine transporter 0.0045 0.0149 0.0513
Trichomonas vaginalis alpha-glucosidase, putative 0.0006 0.0008 0.0063
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0037 0.0119 0.1051
Loa Loa (eye worm) hypothetical protein 0.0052 0.0174 0.06
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0037 0.0119 0.0313
Treponema pallidum ATP-dependent RNA helicase 0.0018 0.0053 0.0108
Schistosoma mansoni hypothetical protein 0.0052 0.0173 0.0777
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0013 0.0034 0.015
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0018 0.0052 0.0136
Brugia malayi Cathepsin L-like precursor 0.0007 0.0011 0.0036
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0012 0.003 0.0063
Toxoplasma gondii histone deacetylase HDAC5 0.0031 0.0097 0.3746
Plasmodium vivax vivapain-2 0.0011 0.0024 0.0899
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0011 0.0027 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Loa Loa (eye worm) TK/INSR protein kinase 0.0135 0.0474 0.1641
Echinococcus granulosus acetylcholinesterase 0.0315 0.1127 0.5056
Onchocerca volvulus 0.0005 0.0005 0.0032
Loa Loa (eye worm) hypothetical protein 0.0409 0.1466 0.5085
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0069 0.031
Trichomonas vaginalis D-aminoacylase, putative 0.0014 0.0035 0.0299
Loa Loa (eye worm) hypothetical protein 0.0078 0.0269 0.0929
Brugia malayi hypothetical protein 0.0087 0.0302 0.1043
Brugia malayi calpain family protein 1 0.003 0.0094 0.0321
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0204 0.0917
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0004 0.0001 0.0045
Trichomonas vaginalis D-aminoacylase, putative 0.0014 0.0035 0.0299
Schistosoma mansoni hypothetical protein 0.0052 0.0173 0.0777
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0011 0.0024 0.0207
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0204 0.0913
Trichomonas vaginalis DNA helicase recq1, putative 0.0011 0.0026 0.0225
Toxoplasma gondii aspartyl protease 0.0005 0.0005 0.0208
Plasmodium falciparum histone deacetylase, putative 0.0075 0.0259 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.0648 0.5742
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0004 0.0001 0.0002
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0053 0.0178 0.0615
Mycobacterium tuberculosis Probable peptidase 0.0013 0.0032 0.003
Plasmodium falciparum histone deacetylase 2 0.0075 0.0259 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0005 0.0004 0.0008
Trichomonas vaginalis alpha-glucosidase, putative 0.0006 0.0008 0.0063
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0005 0.0003 0.0007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0006 0.0009 0.0027
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0059 0.0199 0.0687
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0005 0.0005 0.0024
Schistosoma mansoni chromobox protein 0.0031 0.0099 0.0445
Schistosoma mansoni thyroid hormone receptor 0.0005 0.0006 0.0025
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0011 0.0027 0.0089
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0035 0.1303
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0011 0.0026 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0006 0.0009 0.007
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0015 0.004 0.0175
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0046 0.0398
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0037 0.0119 0.0535
Mycobacterium ulcerans carboxylesterase, LipT 0.2767 1 1
Brugia malayi Bloom's syndrome protein homolog 0.0011 0.0026 0.0087
Echinococcus granulosus cpg binding protein 0.0008 0.0016 0.0065
Schistosoma mansoni histone deacetylase 0.006 0.0201 0.0904
Echinococcus granulosus calpain 7 C02 family 0.0011 0.0026 0.0114
Plasmodium vivax vivapain-3 0.0005 0.0005 0.0174
Echinococcus granulosus histone deacetylase 3 0.006 0.0201 0.09
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0005 0.0006 0.0025
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0024 0.0259
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0024 0.0259
Giardia lamblia Hypothetical protein 0.0012 0.0029 0.0383
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0004 0.0001 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0005 0.0006 0.0016
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0008 0.0013 0.0043
Entamoeba histolytica cysteine proteinase, putative 0.0007 0.0011 0.0122
Schistosoma mansoni BC026374 protein (S09 family) 0.0315 0.1127 0.5058
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.002 0.0058 0.0197
Echinococcus granulosus beta LACTamase domain containing family member 0.0014 0.0035 0.0151
Toxoplasma gondii FATC domain-containing protein 0.0016 0.0042 0.162
Entamoeba histolytica hypothetical protein 0.0015 0.0039 0.0415
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0008 0.0013 0.0043
Schistosoma mansoni cpg binding protein 0.0008 0.0016 0.007
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0005 0.0004 0.0124
Trypanosoma cruzi histone deacetylase, putative 0.0075 0.0259 0.0894
Loa Loa (eye worm) hypothetical protein 0.0005 0.0005 0.0014
Trypanosoma cruzi prolyl endopeptidase 0.0032 0.0101 0.0348
Loa Loa (eye worm) hypothetical protein 0.0073 0.025 0.0863
Trichomonas vaginalis histone deacetylase, putative 0.006 0.0201 0.178
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0011 0.0027 0.0089
Loa Loa (eye worm) hypothetical protein 0.0011 0.0026 0.0086
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0045 0.0149 0.0668
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0018 0.0053 0.0051
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0108 0.0283
Onchocerca volvulus 0.0011 0.0024 0.0202
Brugia malayi SET domain containing protein 0.0006 0.0009 0.0027
Trypanosoma cruzi cysteine peptidase, putative 0.0011 0.0024 0.008
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0053 0.0178 0.0796
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.007 0.0241
Echinococcus granulosus calpain 0.0011 0.0026 0.0114
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0018 0.0052 0.0231
Plasmodium falciparum amino acid transporter, putative 0.0008 0.0013 0.048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0005 0.0006 0.0016
Brugia malayi steroid hormone receptor 0.0005 0.0006 0.0016
Echinococcus multilocularis histone deacetylase 6 0.0075 0.0259 0.0681
Entamoeba histolytica type A flavoprotein, putative 0.0005 0.0004 0.0046
Echinococcus granulosus dna polymerase kappa 0.0011 0.0026 0.0113
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0018 0.0052 0.0179
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0006 0.0006 0.0004
Trypanosoma cruzi oligopeptidase b 0.0013 0.0032 0.0106
Echinococcus granulosus BC026374 protein S09 family 0.0315 0.1127 0.5056
Trichomonas vaginalis antibiotic synthetase, putative 0.0004 0.0001 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0011 0.0026 0.0087
Trichomonas vaginalis ap endonuclease, putative 0.0005 0.0004 0.0029
Plasmodium vivax plasmepsin IV, putative 0.0023 0.0069 0.2647
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0011
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0012 0.003 0.0028
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0011 0.0087
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0005 0.0006 0.0037
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.006 0.0201 0.178
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0008 0.0013 0.006
Leishmania major DNA polymerase kappa, putative 0.0006 0.0006 0.0019
Trichomonas vaginalis nicotinate phosphoribosyltransferase, putative 0.0047 0.0155 0.1368
Brugia malayi hypothetical protein 0.0005 0.0005 0.0014
Mycobacterium ulcerans glutaminase 0.0123 0.0431 0.043
Brugia malayi intermediate filament protein 0.0022 0.0067 0.0229
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0005 0.0006 0.0016
Plasmodium falciparum plasmepsin V 0.0005 0.0005 0.0171
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0036
Plasmodium vivax histone deacetylase, putative 0.0075 0.0259 1
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0007 0.0012 0.001
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0018 0.0053 0.0565
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Echinococcus granulosus lysosomal alpha glucosidase 0.0075 0.0256 0.1146
Echinococcus granulosus serine protein kinase ATM 0.0016 0.0042 0.0184
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0099 0.0873
Trypanosoma cruzi C-8 sterol isomerase, putative 0.08 0.2883 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0015 0.0039 0.0423
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0008 0.0014 0.0045
Giardia lamblia Histone deacetylase 0.006 0.0201 0.3065
Loa Loa (eye worm) hypothetical protein 0.006 0.0201 0.0695
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0037 0.0119 0.1282
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0015 0.0039 0.0038
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0012 0.003 0.0028
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0006 0.0008 0.0024
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0037 0.0119 0.4612
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0011 0.0026 0.0088
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0011
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0005 0.0004 0.003
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0024 0.0073 0.025
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0018 0.0051 0.0131
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0039 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0005 0.0006 0.0016
Echinococcus multilocularis chromobox protein 1 0.0031 0.0099 0.026
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0018 0.0053 0.0459
Schistosoma mansoni acetylcholinesterase 0.0315 0.1127 0.5058
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0039 0.0133
Echinococcus granulosus vesicular acetylcholine transporter 0.0214 0.0759 0.3403
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0005 0.0004 0.0011
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0108 0.0371
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB1 0.0047 0.0155 0.0154
Entamoeba histolytica hypothetical protein 0.0016 0.0042 0.045
Entamoeba histolytica protein kinase, putative 0.0008 0.0014 0.0152
Onchocerca volvulus 0.0315 0.1127 1
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0004 0.003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0067 0.0229
Entamoeba histolytica cysteine protease, putative 0.0005 0.0005 0.0059
Echinococcus multilocularis peregrin 0.0014 0.0037 0.0094
Onchocerca volvulus 0.0009 0.0019 0.0157
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0005 0.0006 0.0025
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0005 0.0005 0.0024
Schistosoma mansoni DNA helicase recq5 0.0008 0.0014 0.0062
Brugia malayi AMP-binding enzyme family protein 0.0004 0.0001 0.0002
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0008 0.0013 0.0043
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0004 0.0001 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Plasmodium falciparum histone acetyltransferase GCN5 0.0011 0.0024 0.0899
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0086 0.0298 0.0297
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0007 0.0011 0.044
Trypanosoma cruzi target of rapamycin kinase 3 0.0011 0.0027 0.0089
Leishmania major histone deacetylase, putative 0.006 0.0201 0.0695
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0011 0.0026 0.0088
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0116
Brugia malayi Heterochromatin protein 1 0.0031 0.0099 0.0341
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0004 0.0001 0.0002
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0089 0.0309 0.0308
Echinococcus multilocularis Chromo domain 0.0005 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0006
Plasmodium vivax calpain, putative 0.0011 0.0026 0.0986
Leishmania major histone deacetylase, putative 0.006 0.0201 0.0695
Loa Loa (eye worm) hypothetical protein 0.0015 0.0039 0.0133
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0011 0.0027 0.0089
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0011 0.0026 0.0088
Loa Loa (eye worm) acyl carrier protein 0.0004 0.0002 0.0003
Entamoeba histolytica cysteine protease, putative 0.0011 0.0024 0.0259
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0032 0.0102 0.0266
Echinococcus multilocularis calpain 7 (C02 family) 0.0011 0.0026 0.0067
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0315 0.1127 0.5056
Schistosoma mansoni cpg binding protein 0.0008 0.0016 0.007
Schistosoma mansoni lipoxygenase 0.0005 0.0005 0.0023
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0006 0.0008 0.0063
Echinococcus granulosus peregrin 0.0014 0.0037 0.016
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0029 0.0089 0.0088
Loa Loa (eye worm) hypothetical protein 0.0008 0.0014 0.0045
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Echinococcus granulosus FTZ F1 alpha 0.0005 0.0006 0.0021
Echinococcus multilocularis acetylcholinesterase 0.0315 0.1127 0.2977
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0011 0.0027 0.0089
Schistosoma mansoni Mername-AA248 (C02 family) 0.0011 0.0026 0.0118
Loa Loa (eye worm) hypothetical protein 0.0045 0.0149 0.0513
Schistosoma mansoni tyrosine kinase 0.0061 0.0208 0.0932
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0005 0.0005 0.015
Schistosoma mansoni histone deacetylase 0.006 0.0201 0.0904
Brugia malayi Calcitonin receptor-like protein seb-1 0.0107 0.0372 0.1287
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0008 0.0014 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0026 0.0087
Trichomonas vaginalis penicillin-binding protein, putative 0.0014 0.0035 0.0299
Echinococcus multilocularis cathepsin L cysteine protease 0.0011 0.0024 0.0061
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0007 0.0012 0.0424
Echinococcus granulosus GPCR family 2 0.0034 0.0108 0.048
Entamoeba histolytica cysteine proteinase, putative 0.0005 0.0005 0.0059
Echinococcus multilocularis hypothetical protein 0.0011 0.0026 0.0067
Echinococcus multilocularis lamin 0.0022 0.0067 0.0175
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0037 0.0119 0.1051
Toxoplasma gondii prolyl endopeptidase 0.0032 0.0101 0.3918
Onchocerca volvulus 0.0018 0.005 0.0432
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1049 0.3784 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.005 0.0223
Toxoplasma gondii hypothetical protein 0.0008 0.0013 0.0515
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0026 0.0087
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0014 0.0035 0.0155
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0116
Onchocerca volvulus 0.0008 0.0013 0.0106
Brugia malayi CHD4 protein 0.0006 0.0006 0.0017
Plasmodium vivax SET domain protein, putative 0.003 0.0094 0.3602
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0005 0.0003 0.0074
Plasmodium falciparum plasmepsin IV 0.0023 0.0069 0.2647
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0016
Brugia malayi Carboxylesterase family protein 0.0315 0.1127 0.3907
Entamoeba histolytica hypothetical protein 0.0067 0.0227 0.2436
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0004 0.003
Echinococcus granulosus dnaJ subfamily B 0.0111 0.0388 0.174
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0005 0.0004 0.0015
Loa Loa (eye worm) apoptosis regulator protein 0.0052 0.0173 0.0598
Echinococcus granulosus para nitrobenzyl esterase 0.0315 0.1127 0.5056
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0015 0.0039 0.0037
Onchocerca volvulus 0.0008 0.0013 0.0106
Plasmodium vivax aspartyl protease, putative 0.0005 0.0005 0.0171
Chlamydia trachomatis sulfite reductase 0.0008 0.0016 0.0225
Echinococcus multilocularis chromobox protein 2 0.0005 0.0004 0.0009
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0005 0.0006 0.0012
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0008 0.0014 0.0535
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0011 0.0027 0.009
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0035 0.0116
Trypanosoma cruzi histone deacetylase 1, putative 0.006 0.0201 0.0695
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0007 0.001 0.0343
Onchocerca volvulus Alhambra homolog 0.0013 0.0033 0.0282
Brugia malayi Papain family cysteine protease containing protein 0.0011 0.0024 0.008
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0183 0.0648 0.6962
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0039 0.0131
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0011 0.0027 0.0119
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0013 0.0034 0.015
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0039 0.0128 0.0576
Plasmodium vivax heterochromatin protein 1, putative 0.0005 0.0004 0.0126
Echinococcus multilocularis lysosomal alpha glucosidase 0.0075 0.0256 0.0675
Echinococcus granulosus integrin beta 2 0.0027 0.0084 0.0371
Giardia lamblia Sgs1 DNA helicase, putative 0.0008 0.0014 0.015
Mycobacterium tuberculosis Two component sensor kinase [first part] 0.0009 0.0018 0.0017
Leishmania major glycosyl hydrolase-like protein 0.0006 0.0008 0.0024
Onchocerca volvulus 0.0315 0.1127 1
Entamoeba histolytica hypothetical protein 0.0067 0.0227 0.2436
Schistosoma mansoni lipoxygenase 0.0015 0.004 0.018
Echinococcus granulosus histone acetyltransferase KAT2B 0.0038 0.0124 0.0554
Brugia malayi hypothetical protein 0.0005 0.0004 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0026 0.0087
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0037 0.0119 0.041
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0183 0.0648 0.6962
Mycobacterium tuberculosis Conserved protein 0.0014 0.0035 0.0033
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0005 0.0006 0.0025
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0013 0.0032 0.0106
Loa Loa (eye worm) hypothetical protein 0.0018 0.0053 0.0179
Schistosoma mansoni jumonji domain containing protein 0.0004 0.0001 0.0004
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0089 0.0396
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0005 0.0006 0.0025
Echinococcus granulosus lamin 0.0022 0.0067 0.0297
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0094 0.0417
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0008 0.0013 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0011 0.0024 0.0207
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Schistosoma mansoni hypothetical protein 0.0111 0.0388 0.1744
Brugia malayi flavodoxin family protein 0.0013 0.0034 0.0116
Mycobacterium ulcerans two component regulator - sensor kinase 0.0012 0.003 0.0028
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0011 0.0087
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0037 0.0119 0.1051
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0008 0.0013 0.006
Schistosoma mansoni loxhd1 0.0005 0.0005 0.0023
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0011 0.0026 0.1173
Trypanosoma cruzi nicotinate phosphoribosyltransferase, putative 0.0047 0.0155 0.0534
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0016
Schistosoma mansoni alpha-glucosidase 0.0064 0.0219 0.0981
Loa Loa (eye worm) hypothetical protein 0.0023 0.0069 0.0237
Entamoeba histolytica acyl-coA synthetase, putative 0.0015 0.0039 0.0423
Brugia malayi PHD-finger family protein 0.0013 0.0033 0.0112
Brugia malayi Glycosyl hydrolases family 31 protein 0.0075 0.0256 0.0886
Echinococcus granulosus cathepsin L cysteine proteinase 0.0011 0.0024 0.0104
Onchocerca volvulus Cathepsin L homolog 0.0011 0.0024 0.0202
Mycobacterium tuberculosis Probable thioesterase TesA 0.0008 0.0015 0.0014
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0005 0.0004 0.003
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0008 0.0014 0.0034
Trichomonas vaginalis chromobox protein, putative 0.0005 0.0004 0.003
Loa Loa (eye worm) hypothetical protein 0.0315 0.1127 0.3907
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0017 0.0046 0.0491
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0006 0.0006 0.0026
Echinococcus multilocularis calpain 0.0011 0.0026 0.0067
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0011 0.0024 0.008
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0008 0.0016 0.007
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0315 0.1127 0.5058
Loa Loa (eye worm) FAD binding domain-containing protein 0.0008 0.0016 0.0051
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0005 0.0004 0.0045
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0005 0.0004 0.0128
Loa Loa (eye worm) RecQ helicase 0.0011 0.0026 0.0087
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0024 0.0073 0.025
Brugia malayi Kelch motif family protein 0.0006 0.0006 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0112 0.0504
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0053 0.0178 0.0469
Toxoplasma gondii histone deacetylase HDAC1 0.0075 0.0259 1
Schistosoma mansoni jumonji domain containing protein 0.0034 0.0109 0.049
Onchocerca volvulus 0.0011 0.0024 0.0202
Trypanosoma cruzi major cysteine proteinase, putative 0.0015 0.0039 0.0132
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0005 0.0006 0.0012
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0007 0.0009 0.0357
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0033 0.1249
Schistosoma mansoni hypothetical protein 0.0034 0.0108 0.0484
Brugia malayi FAD binding domain containing protein 0.0013 0.0034 0.0116
Treponema pallidum methylgalactoside ABC transporter, periplasmic galactose-binding protein (mglB-1) 0.124 0.4473 1
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0015 0.0039 0.0077
Plasmodium vivax unspecified product 0.0005 0.0005 0.0174
Brugia malayi Isocitrate dehydrogenase 0.0007 0.0012 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0005 0.0006 0.0016
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0012 0.0054
Trypanosoma cruzi p450 reductase, putative 0.0013 0.0034 0.0116
Entamoeba histolytica type A flavoprotein, putative 0.0005 0.0004 0.0046
Schistosoma mansoni NADPH flavin oxidoreductase 0.0007 0.001 0.0046
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0018 0.0051 0.0172
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0037 0.0119 0.041
Echinococcus multilocularis thyroid hormone receptor alpha 0.0005 0.0006 0.0012
Loa Loa (eye worm) calpain 5 0.0008 0.0014 0.0046
Echinococcus granulosus prolyl endopeptidase 0.0032 0.0101 0.045
Leishmania major phosphatidylinositol 3-kinase, putative 0.0011 0.0027 0.0089
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0024 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0006 0.0009 0.007
Brugia malayi Cathepsin L-like precursor 0.0011 0.0024 0.008
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0006 0.0009 0.0021
Onchocerca volvulus Cathepsin F homolog 0.0011 0.0024 0.0202
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0015 0.0038 0.0037
Brugia malayi Cathepsin L-like precursor 0.0011 0.0024 0.008
Entamoeba histolytica cysteine protease, putative 0.0005 0.0005 0.0059
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0006 0.0016
Echinococcus granulosus cathepsin L cysteine protease 0.0005 0.0005 0.002
Schistosoma mansoni hypothetical protein 0.0005 0.0004 0.0019
Toxoplasma gondii flavodoxin domain-containing protein 0.0007 0.001 0.0379
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0015 0.0038 0.013
Leishmania major cytochrome P450 reductase, putative 0.0012 0.0029 0.0097
Echinococcus multilocularis cathepsin L cysteine protease 0.0011 0.0024 0.0061
Loa Loa (eye worm) solute carrier family 6 member 4 0.0045 0.0149 0.0513
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0014 0.0035 0.0033
Trypanosoma cruzi cysteine peptidase, putative 0.0023 0.007 0.0241
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0052 0.0173 0.0455
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0004 0.0001 0.0002
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0018 0.0051 0.0544
Loa Loa (eye worm) serotonin transporter b 0.0045 0.0149 0.0513
Trypanosoma brucei DNA polymerase IV, putative 0.0011 0.0026 0.0087
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0005 0.0004 0.0014
Entamoeba histolytica hypothetical protein 0.0005 0.0004 0.0045
Trichomonas vaginalis esterase, putative 0.0014 0.0035 0.0299
Loa Loa (eye worm) isocitrate dehydrogenase 0.0007 0.0012 0.0038
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0008 0.0013 0.0033
Mycobacterium leprae Probable lipase LipE 0.0014 0.0035 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0005 0.0005 0.0004
Brugia malayi vesicular acetylcholine transporter unc-17 0.0214 0.0759 0.2629
Schistosoma mansoni diflavin oxidoreductase 0.0007 0.001 0.0044
Entamoeba histolytica cysteine protease, putative 0.0005 0.0005 0.0059
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0016
Trypanosoma cruzi oligopeptidase b 0.0013 0.0032 0.0106
Brugia malayi isocitrate dehydrogenase 0.0007 0.0012 0.0038
Echinococcus granulosus eukaryotic initiation factor 4A 0.0018 0.0053 0.0232
Trichomonas vaginalis spcc417.12 protein, putative 0.0315 0.1127 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0008 0.0015 0.0013
Schistosoma mansoni memapsin-2 (A01 family) 0.0005 0.0005 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0004 0.003
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0005 0.0005 0.0024
Loa Loa (eye worm) hypothetical protein 0.0046 0.0152 0.0524
Trypanosoma brucei glucosidase, putative 0.0017 0.0046 0.0155
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0107 0.0372 0.1287
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0094 0.0421
Onchocerca volvulus 0.0005 0.0005 0.0032
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0214 0.0759 0.2629
Plasmodium falciparum plasmepsin IX 0.0005 0.0005 0.0171
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0016
Onchocerca volvulus 0.0035 0.0112 0.0985
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0204 0.0203
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0261 0.093 0.8252
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.007 0.0241
Trichomonas vaginalis bromodomain-containing protein, putative 0.0012 0.0028 0.0238
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0011 0.0027 0.0089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0005 0.0005 0.0016
Echinococcus multilocularis para nitrobenzyl esterase 0.0315 0.1127 0.2977
Schistosoma mansoni alpha glucosidase 0.0017 0.0046 0.0205
Toxoplasma gondii ABC1 family protein 0.0014 0.0035 0.1335
Onchocerca volvulus 0.0022 0.0067 0.0583
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0018 0.0053 0.0179
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0011 0.0026 0.0088
Onchocerca volvulus 0.0022 0.0067 0.0583
Loa Loa (eye worm) carboxylesterase 0.0315 0.1127 0.3907
Onchocerca volvulus 0.0011 0.0024 0.0202
Loa Loa (eye worm) glutaminase 0.0123 0.0431 0.1492
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0008 0.0013 0.006
Echinococcus multilocularis neutral alpha glucosidase AB 0.0017 0.0046 0.0118
Loa Loa (eye worm) ctsf protein 0.0011 0.0024 0.008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.007 0.0241
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0005 0.0005 0.0024
Loa Loa (eye worm) hypothetical protein 0.0007 0.0012 0.0039
Mycobacterium ulcerans esterase/lipase LipP 0.0014 0.0035 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Echinococcus multilocularis histone deacetylase 6 0.0075 0.0259 0.0681
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0006 0.0008 0.0063
Trypanosoma cruzi cysteine proteinase, putative 0.0005 0.0005 0.0016
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0012 0.0028 0.0238
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0108 0.0371
Plasmodium vivax vivapain-2 0.0011 0.0024 0.0899
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0024 0.0073 0.0191
Schistosoma mansoni cpg binding protein 0.0008 0.0014 0.0062
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0012 0.003 0.0028
Plasmodium vivax flavodoxin domain containing protein 0.0012 0.0029 0.1081
Brugia malayi M-phase phosphoprotein, mpp8 0.0005 0.0004 0.0011
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0075 0.0256 0.0886
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0013 0.0032 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0005 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0043
Onchocerca volvulus 0.0052 0.0174 0.1533
Trichomonas vaginalis alpha-glucosidase, putative 0.0006 0.0008 0.0063
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0018 0.0049 0.0425
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0011 0.0026 0.0024
Leishmania major nicotinate phosphoribosyltransferase, putative 0.0047 0.0155 0.0534
Echinococcus granulosus sodium and chloride dependent glycine 0.0008 0.0013 0.0055
Brugia malayi Muscleblind-like protein 0.0078 0.0269 0.0929
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0013 0.0034 0.0115
Schistosoma mansoni hypothetical protein 0.0005 0.0003 0.0016
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0007 0.0012 0.0029
Trypanosoma cruzi cysteine peptidase, putative 0.0023 0.007 0.0241
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0005 0.0004 0.0045
Echinococcus multilocularis methionine synthase reductase 0.0008 0.0016 0.0039
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0016 0.0043 0.0371
Leishmania major 4-coumarate:coa ligase-like protein 0.0015 0.0039 0.0133
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0043
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0005 0.0004 0.0045
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0017 0.0046 0.0155
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0008 0.0014 0.0013
Brugia malayi calpain 7 0.0011 0.0026 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0004 0.003
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0005 0.0006 0.0021
Echinococcus multilocularis calpain A 0.0032 0.0102 0.0267
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0005 0.0004 0.0003
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0018 0.0053 0.0236
Brugia malayi chromobox protein homolog 3 0.0018 0.0049 0.0168
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0094 0.0245
Brugia malayi hypothetical protein 0.0008 0.0013 0.0043
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0005 0.0005 0.0024
Trypanosoma brucei unspecified product 0.0009 0.002 0.0065
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0005 0.0004 0.0128
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0024 0.0108
Schistosoma mansoni ap endonuclease 0.0005 0.0004 0.0019
Leishmania major cathepsin L-like protease 0.0023 0.007 0.0241
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0006 0.0006 0.0022
Brugia malayi Papain family cysteine protease containing protein 0.0005 0.0005 0.0016
Toxoplasma gondii hypothetical protein 0.0008 0.0013 0.0515
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0061 0.0208 0.0928
Trypanosoma brucei histone deacetylase 3 0.0075 0.0259 0.0894
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0008 0.0014 0.0535
Entamoeba histolytica cysteine proteinase, putative 0.0005 0.0005 0.0059
Mycobacterium tuberculosis Conserved protein 0.0014 0.0035 0.0033
Echinococcus granulosus Chromobox protein 3 0.0005 0.0004 0.0015
Trichomonas vaginalis sulfite reductase, putative 0.0013 0.0034 0.0297
Echinococcus granulosus methionine synthase reductase 0.0008 0.0016 0.0066
Entamoeba histolytica histone deacetylase, putative 0.006 0.0201 0.2164
Echinococcus multilocularis cysteine protease 0.0011 0.0024 0.0061
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0011 0.0027 0.0089
Schistosoma mansoni blooms syndrome DNA helicase 0.0007 0.0012 0.0053
Onchocerca volvulus 0.0236 0.0839 0.7443
Leishmania major cathepsin L-like protease 0.0011 0.0024 0.008
Mycobacterium tuberculosis Conserved protein 0.0014 0.0035 0.0033
Trypanosoma cruzi histone deacetylase, putative 0.0031 0.0097 0.0333
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.001 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0116
Plasmodium falciparum plasmepsin II 0.0023 0.0069 0.2647
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0012 0.0028 0.1068
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0006 0.0006 0.0013
Loa Loa (eye worm) carboxylesterase 0.0315 0.1127 0.3907
Trypanosoma brucei DNA polymerase kappa, putative 0.0006 0.0006 0.0019
Trypanosoma brucei kinesin, putative 0.0008 0.0014 0.0046
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0005 0.0006 0.0012
Toxoplasma gondii histone deacetylase HDAC3 0.006 0.0201 0.7787
Brugia malayi nuclear receptor NHR-88 0.0005 0.0006 0.0016
Echinococcus granulosus microtubule associated protein 2 0.062 0.2228 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.0648 0.5742
Schistosoma mansoni retinoic acid receptor RXR 0.0005 0.0006 0.0025
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0008 0.0014 0.0028
Schistosoma mansoni tyrosine kinase 0.0135 0.0474 0.2126
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0005 0.0006 0.0012
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0022 0.0067 0.0229
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0084 0.0287
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0052 0.0173 0.0777
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0026 0.0087
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0013 0.0034 0.0033
Plasmodium falciparum eukaryotic initiation factor 4A 0.0018 0.0053 0.2002
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.001 0.0021 0.002
Trypanosoma brucei glycosyl hydrolase-like protein 0.0006 0.0008 0.0024
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0004 0.0001 0.0015
Echinococcus multilocularis survival motor neuron protein 1 0.0087 0.0302 0.0795
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0032 0.0101 0.0455
Schistosoma mansoni hypothetical protein 0.0013 0.0033 0.0149
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0315 0.1127 0.1126
Plasmodium falciparum cysteine proteinase falcipain 1 0.0005 0.0005 0.0174
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0011 0.0027 0.009
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0008 0.0014 0.0045
Mycobacterium ulcerans polyketide synthase Pks9 0.0006 0.0009 0.0008
Echinococcus granulosus geminin 0.0154 0.0543 0.2435
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0043 0.0141 0.0371
Brugia malayi PHD-finger family protein 0.0005 0.0003 0.0006
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0204 0.0537
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0018 0.0051 0.0172
Trypanosoma brucei prolyl endopeptidase 0.0032 0.0101 0.0348
Loa Loa (eye worm) intermediate filament protein 0.0022 0.0067 0.0229
Loa Loa (eye worm) hypothetical protein 0.08 0.2883 1
Leishmania major cysteine peptidase A (CPA) 0.0011 0.0024 0.008
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0011 0.0026 0.0088
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0008 0.0014 0.0499
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0016 0.0043 0.0371
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0013 0.0032 0.0106
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0018 0.0051 0.0172
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0013 0.0034 0.0116
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0018 0.0053 0.0179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0005 0.0005 0.0041
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0005 0.0004 0.0124
Brugia malayi Histone deacetylase family protein 0.0075 0.0259 0.0894
Trypanosoma cruzi cysteine proteinase, putative 0.0005 0.0005 0.0016
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0315 0.1127 0.2977
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.0648 0.5742
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0026 0.0225
Plasmodium vivax histone deacetylase 1, putative 0.006 0.0201 0.7779
Loa Loa (eye worm) hypothetical protein 0.0015 0.0039 0.0133
Schistosoma mansoni hypothetical protein 0.0005 0.0005 0.0023
Echinococcus multilocularis sodium and chloride dependent glycine 0.0008 0.0013 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.007 0.0241
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0004 0.0001 0.0002
Plasmodium vivax acyl-CoA synthetase, putative 0.0011 0.0026 0.0962
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0008 0.0013 0.006
Echinococcus multilocularis acetylcholinesterase 0.0315 0.1127 0.2977
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0037 0.0119 0.041
Brugia malayi Glycosyl hydrolases family 31 protein 0.0017 0.0046 0.0155
Entamoeba histolytica cysteine proteinase 1, putative 0.0005 0.0005 0.0059
Loa Loa (eye worm) FAD binding domain-containing protein 0.0013 0.0034 0.0116
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0006 0.0009 0.0027
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.006 0.0201 0.178
Brugia malayi Carboxylesterase family protein 0.0315 0.1127 0.3907
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0011 0.0027 0.0286
Brugia malayi photoreceptor-specific nuclear receptor 0.0005 0.0006 0.0016
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0005 0.0005 0.0024
Leishmania major histone deacetylase, putative 0.0075 0.0259 0.0894
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0013 0.0034 0.0116
Echinococcus granulosus jumonji domain containing protein 0.0018 0.0052 0.0228
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0004 0.0001 0.0002
Plasmodium falciparum nitric oxide synthase, putative 0.0013 0.0034 0.1296
Brugia malayi hypothetical protein 0.0006 0.0006 0.0017
Trichomonas vaginalis set domain proteins, putative 0.0236 0.0839 0.7444
Loa Loa (eye worm) calpain 0.0011 0.0026 0.0088
Schistosoma mansoni chromobox protein 0.0005 0.0004 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0005 0.0006 0.0016
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0005 0.0006 0.0021
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.001 0.0021 0.0044
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0008 0.0013 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.007 0.0241
Echinococcus multilocularis ecdysone induced protein 78C 0.0005 0.0006 0.0012
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0015 0.0039 0.0085
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0004 0.0001 0.0037
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0011 0.0087
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0043 0.0141 0.063
Leishmania major kinesin, putative 0.0008 0.0014 0.0046
Plasmodium vivax hypothetical protein, conserved 0.0005 0.0004 0.0126
Loa Loa (eye worm) hypothetical protein 0.0022 0.0066 0.0224
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0043
Onchocerca volvulus Protein ultraspiracle homolog 0.0005 0.0006 0.0037
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0016 0.0043 0.3347
Trichomonas vaginalis sucrase-isomaltase, putative 0.0017 0.0046 0.0398
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0005 0.0006 0.0016
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0108 0.048
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0017 0.0046 0.0491
Schistosoma mansoni histone deacetylase hda2 0.0031 0.0097 0.0435
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Schistosoma mansoni nicotinate phosphoribosyltransferase 0.0047 0.0155 0.0695
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0008 0.0013 0.0055
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0037 0.0119 1
Echinococcus multilocularis histone deacetylase 1 0.006 0.0201 0.053
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0006 0.0006 0.0005
Echinococcus multilocularis RUN 0.0005 0.0005 0.0011
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0005 0.0004 0.0126
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0013 0.0034 0.0088
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0046 0.0398
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0052 0.0173 0.0598
Entamoeba histolytica cysteine protease, putative 0.0005 0.0005 0.0059
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0037 0.0119 0.041
Plasmodium falciparum plasmepsin VII 0.0005 0.0005 0.0171
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0014 0.0035 0.0116
Onchocerca volvulus 0.0011 0.0024 0.0202
Trypanosoma brucei DNA polymerase kappa, putative 0.0008 0.0016 0.0053
Brugia malayi Papain family cysteine protease containing protein 0.0005 0.0005 0.0016
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0018 0.0053 0.0459
Mycobacterium ulcerans polyketide synthase 0.001 0.0021 0.002
Trichomonas vaginalis penicillin-binding protein, putative 0.0014 0.0035 0.0299
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0013 0.0034 0.0116
Onchocerca volvulus 0.0011 0.0024 0.0202
Trichomonas vaginalis D-aminoacylase, putative 0.0014 0.0035 0.0299
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0039 0.0128 0.0337
Echinococcus multilocularis sodium and chloride dependent glycine 0.0008 0.0013 0.0033
Echinococcus granulosus lysine specific demethylase 5A 0.0016 0.0045 0.0197
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0039 0.0038
Brugia malayi FAD binding domain containing protein 0.0008 0.0016 0.0051
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0012 0.003 0.0063
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0011 0.0087
Schistosoma mansoni tyrosine kinase 0.0061 0.0208 0.0932
Brugia malayi Cathepsin L-like cysteine proteinase 0.0007 0.0011 0.0036
Onchocerca volvulus 0.0007 0.0011 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Echinococcus granulosus histone deacetylase 6 0.0075 0.0259 0.1157
Loa Loa (eye worm) oxidoreductase 0.0004 0.0001 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0005 0.0003 0.0074
Entamoeba histolytica type A flavoprotein, putative 0.0005 0.0004 0.0046
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0025 0.0078 0.0267
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0024 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0005 0.0006 0.0016
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0012 0.003 0.0028
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0015 0.0039 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0011 0.0024 0.0207
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.001 0.0021 0.002
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0008 0.0015 0.0031
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0024 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0046 0.0155
Loa Loa (eye worm) hypothetical protein 0.0315 0.1127 0.3907
Schistosoma mansoni neuroligin 3 (S09 family) 0.0315 0.1127 0.5058
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.0648 0.5742
Entamoeba histolytica hypothetical protein 0.0005 0.0004 0.0045
Brugia malayi Protein cec-1. 0.0005 0.0004 0.0011
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0004 0.0001 0.0001
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0008 0.0013 0.0055
Onchocerca volvulus 0.0005 0.0005 0.0035
Schistosoma mansoni sodium/chloride dependent transporter 0.0008 0.0013 0.006
Echinococcus multilocularis PHD finger protein rhinoceros 0.0013 0.0033 0.0085
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0037 0.0119 0.0118
Echinococcus multilocularis lipoxygenase domain containing protein 0.0005 0.0005 0.0011
Brugia malayi aspartic protease BmAsp-2, identical 0.0005 0.0005 0.0015
Plasmodium vivax aspartyl protease, putative 0.0005 0.0005 0.0171
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0018 0.0051 0.0223
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0015 0.0039 0.0037
Trypanosoma cruzi cysteine protease, putative 0.0005 0.0005 0.0016
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB2 0.0047 0.0155 0.0154
Echinococcus multilocularis lipoxygenase domain containing protein 0.0005 0.0005 0.0011
Echinococcus granulosus Chromo domain 0.0005 0.0004 0.0015
Brugia malayi Cathepsin L-like precursor 0.0011 0.0024 0.008
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0024 0.0073 0.0251
Loa Loa (eye worm) hypothetical protein 0.0005 0.0005 0.0014
Echinococcus granulosus serotonin transporter 0.0045 0.0149 0.0664
Schistosoma mansoni glutaminase 0.0123 0.0431 0.1934
Trichomonas vaginalis PIKK family atypical protein kinase 0.0006 0.0009 0.007
Loa Loa (eye worm) beta-lactamase 0.0014 0.0035 0.0116
Echinococcus multilocularis Polycystic kidney disease protein 0.0005 0.0005 0.0011
Toxoplasma gondii PHD-finger domain-containing protein 0.0013 0.0033 0.1281
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0037 0.0119 0.0313
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0006 0.0009 0.0332
Echinococcus multilocularis calpain family protein 1, d 0.0022 0.0065 0.017
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0005 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0052 0.0173 0.0598
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0005 0.0004 0.0045
Loa Loa (eye worm) hypothetical protein 0.0005 0.0005 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0011 0.0094
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0005 0.0004 0.0011
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0037 0.0119 0.4592
Plasmodium vivax aspartyl protease, putative 0.0005 0.0005 0.0171
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.007 0.0241
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.006 0.0201 0.178
Plasmodium vivax vivapain-1 0.0005 0.0005 0.0174
Schistosoma mansoni ap endonuclease 0.0005 0.0004 0.0019
Mycobacterium ulcerans lipase LipD 0.0014 0.0035 0.0033
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0037 0.0119 0.041
Echinococcus granulosus Polycystic kidney disease protein 0.0005 0.0005 0.0018
Echinococcus multilocularis histone deacetylase 0.0075 0.0259 0.0681
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0008 0.0013 0.006
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0008 0.0013 0.0043
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0007 0.0012 0.0038
Entamoeba histolytica hypothetical protein 0.0067 0.0227 0.2436
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0018 0.0052 0.0179
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0011 0.0026 0.0088
Loa Loa (eye worm) hypothetical protein 0.0005 0.0005 0.0015
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0013 0.0034 0.0116
Plasmodium vivax RNA helicase-1, putative 0.0018 0.0053 0.2002
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0032 0.0102 0.0457
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0004 0.003
Brugia malayi hypothetical protein 0.0005 0.0005 0.0014
Trypanosoma brucei histone deacetylase 4 0.0075 0.0259 0.0894
Onchocerca volvulus 0.0014 0.0036 0.0303
Echinococcus multilocularis prolyl endopeptidase 0.0032 0.0101 0.0265
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0261 0.093 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0008 0.006
Leishmania major alpha glucosidase II subunit, putative 0.0017 0.0046 0.0155
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0014 0.0035 0.0116
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0011 0.0024 0.0061
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0018 0.0053 0.0752
Schistosoma mansoni hypothetical protein 0.0034 0.0108 0.0484
Onchocerca volvulus 0.0005 0.0004 0.0025
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0005 0.0006 0.0016
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0017 0.0046 0.0398
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0005 0.0004 0.003
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0013 0.0034 0.0116
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0011 0.0027 0.0089
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0015 0.0039 0.0038
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0052 0.0173 0.0773
Brugia malayi polk-prov protein 0.0008 0.0016 0.0053
Schistosoma mansoni microtubule-associated protein tau 0.062 0.2228 1
Entamoeba histolytica hypothetical protein 0.0005 0.0004 0.0045
Schistosoma mansoni calpain (C02 family) 0.0011 0.0026 0.0118
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0204 0.0917
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0005 0.0004 0.0163
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0011 0.0087
Brugia malayi Carboxylesterase family protein 0.0315 0.1127 0.3907
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0037 0.0119 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0094 0.0421
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0037 0.0119 0.1051
Brugia malayi Cathepsin L-like precursor 0.0011 0.0024 0.008
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0018 0.0053 0.0136
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0037 0.0119 0.1282
Echinococcus granulosus lipoxygenase domain containing protein 0.0005 0.0005 0.0018
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0037 0.0119 0.4612
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0008 0.0016 0.0053
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0039 0.0133
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0008 0.0016 0.0053
Loa Loa (eye worm) hypothetical protein 0.003 0.0094 0.0321
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0012 0.003 0.0028
Echinococcus granulosus neuroligin 0.0315 0.1127 0.5056
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0008 0.0014 0.0013
Echinococcus multilocularis serine protein kinase ATM 0.0016 0.0042 0.0108
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0006 0.0008 0.0086
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0016 0.0042 0.0142
Brugia malayi ecdysteroid receptor 0.0005 0.0006 0.0016
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.001 0.0021 0.007
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0005 0.0005 0.0024
Trypanosoma brucei prolyl oligopeptidase, putative 0.0013 0.0032 0.0106
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0008 0.006
Brugia malayi Cytochrome P450 family protein 0.0013 0.0034 0.0113
Onchocerca volvulus 0.0005 0.0005 0.0035
Loa Loa (eye worm) flavodoxin family protein 0.0005 0.0004 0.0011
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0008 0.0013 0.006
Leishmania major hypothetical protein, conserved 0.0014 0.0035 0.0116
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0009 0.002 0.0019
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0059 0.0199 0.089
Onchocerca volvulus 0.0014 0.0035 0.0294
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0013 0.0032 0.003
Schistosoma mansoni acetyl-CoA synthetase 0.0004 0.0001 0.0006
Trypanosoma brucei histone deacetylase 1 0.006 0.0201 0.0695
Echinococcus multilocularis histone deacetylase 8 0.0031 0.0097 0.0253
Brugia malayi cytoplasmic intermediate filament protein 0.0012 0.0029 0.0098
Mycobacterium leprae Probable polyketide synthase Pks1 0.001 0.0023 0.0049
Echinococcus multilocularis 0.0018 0.0049 0.0128
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0116
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0015 0.0039 0.0085
Trypanosoma cruzi DNA polymerase kappa, putative 0.0011 0.0026 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0005 0.0005 0.0004
Trichomonas vaginalis glutaminase, putative 0.0123 0.0431 0.382
Echinococcus granulosus sodium and chloride dependent glycine 0.0008 0.0013 0.0055
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0023 0.0069 0.2674
Schistosoma mansoni sodium/chloride dependent transporter 0.0045 0.0149 0.0668
Echinococcus granulosus histone deacetylase 8 0.0031 0.0097 0.043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0011
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0013 0.0034 0.0116
Loa Loa (eye worm) hypothetical protein 0.0315 0.1127 0.3907
Loa Loa (eye worm) hypothetical protein 0.0011 0.0024 0.008
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0052 0.0173 0.0455
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0059 0.0199 0.0524
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0015 0.0038 0.0037
Leishmania major acetyl-CoA synthetase, putative 0.0004 0.0001 0.0002
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0013 0.0034 0.0116
Schistosoma mansoni tyrosine kinase 0.0135 0.0474 0.2126
Brugia malayi AMP-binding enzyme family protein 0.0004 0.0001 0.0002
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0004 0.0001 0.0004
Echinococcus granulosus histone acetyltransferase KAT2B 0.0012 0.0028 0.012
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0005 0.0004 0.0011
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0315 0.1127 1
Brugia malayi Furin-like cysteine rich region family protein 0.0061 0.0208 0.0717
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0011 0.0087
Trichomonas vaginalis chromobox protein, putative 0.0019 0.0054 0.0473
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0005 0.0004 0.0019
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.001 0.0024 0.0879
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Schistosoma mansoni tyrosine kinase 0.006 0.0204 0.0914
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0018 0.0053 0.0459
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0012 0.003 0.0028
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0089 0.0309 0.0688
Trypanosoma cruzi cysteine peptidase, putative 0.0023 0.007 0.0241
Schistosoma mansoni jumonji/arid domain-containing protein 0.0016 0.0045 0.0201
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0011 0.0027 0.0119
Onchocerca volvulus 0.0019 0.0053 0.0457
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0024 0.0073 0.025
Mycobacterium ulcerans polyketide synthase 0.001 0.0023 0.0022
Trypanosoma brucei antigen, putative 0.0011 0.0026 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0014 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0034 0.0108 0.0371
Mycobacterium ulcerans Type I modular polyketide synthase 0.001 0.0021 0.002
Entamoeba histolytica protein kinase rad3, putative 0.0006 0.0009 0.0094
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0046 0.0155
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0005 0.0005 0.0004
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0006 0.0006 0.0019
Schistosoma mansoni hypothetical protein 0.0052 0.0173 0.0777
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0005 0.0005 0.0008
Mycobacterium ulcerans polyketide synthase Pks13 0.0015 0.0038 0.0037
Echinococcus granulosus histone deacetylase 1 0.006 0.0201 0.09
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0016
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0013 0.048
Toxoplasma gondii target of rapamycin (TOR), putative 0.0011 0.0027 0.1028
Giardia lamblia DINP protein human, muc B family 0.0006 0.0006 0.0035
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0005 0.0003 0.0007
Brugia malayi Associated with TFs and helicases family protein 0.0005 0.0004 0.0011
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.001 0.0023 0.0022
Leishmania major phosphatidylinositol kinase related protein, putative 0.0011 0.0027 0.0089
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0037 0.0119 0.0531
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0011
Brugia malayi Histone deacetylase family protein 0.0075 0.0259 0.0894
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0011 0.0027 0.0089
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0011
Schistosoma mansoni sodium-dependent amino acid transporter 0.0008 0.0013 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0003 0.0023
Loa Loa (eye worm) helicase 0.0005 0.0004 0.0011
Schistosoma mansoni lamin 0.0022 0.0067 0.0301
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0015 0.0039 0.0038
Leishmania major acetyl-CoA synthetase, putative 0.0004 0.0001 0.0002
Loa Loa (eye worm) calpain family protein 1 0.003 0.0094 0.0321
Mycobacterium tuberculosis Probable lipase LipE 0.0014 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0004 0.0001 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0007 0.0011 0.0093
Loa Loa (eye worm) hypothetical protein 0.0074 0.0252 0.087
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0049 0.043
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0204 0.0203
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0045 0.0149 0.0513
Mycobacterium leprae Possible D-ribose-binding protein 0.124 0.4473 1
Trichomonas vaginalis chromobox protein, putative 0.0019 0.0054 0.0473
Echinococcus multilocularis calpain 5 0.0011 0.0026 0.0067
Schistosoma mansoni jumonji/arid domain-containing protein 0.0016 0.0045 0.0201
Brugia malayi Valyl-tRNA synthetase 0.0005 0.0004 0.0011
Schistosoma mansoni DNA helicase recq1 0.0008 0.0014 0.0062
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0012 0.003 0.0028
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0005 0.0004 0.0163
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0037 0.0119 0.0258
Schistosoma mansoni intermediate filament proteins 0.0022 0.0067 0.0301
Mycobacterium ulcerans Type I modular polyketide synthase 0.001 0.0021 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0026 0.0087
Entamoeba histolytica acetyltransferase, GNAT family 0.0011 0.0024 0.0259
Trichomonas vaginalis antibiotic synthetase, putative 0.0004 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0087 0.0302 0.1043
Toxoplasma gondii aspartyl protease ASP3 0.0005 0.0005 0.0208
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0039 0.0038
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0012 0.003 0.0028
Echinococcus granulosus chromobox protein 2 0.0005 0.0004 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Brugia malayi beta-lactamase family protein 0.0014 0.0035 0.0116
Brugia malayi Carboxylesterase family protein 0.0315 0.1127 0.3907
Echinococcus granulosus neutral alpha glucosidase AB 0.0017 0.0046 0.0201
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0011 0.0026 0.0088
Brugia malayi glutaminase DH11.1 0.0123 0.0431 0.1492
Giardia lamblia GTOR 0.0011 0.0027 0.0349
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0008 0.0013 0.0515
Loa Loa (eye worm) hypothetical protein 0.0026 0.0081 0.0279
Toxoplasma gondii histone deacetylase HDAC2 0.006 0.0201 0.7787
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0008 0.0014 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0024 0.0207
Plasmodium falciparum nicotinate phosphoribosyltransferase, putative 0.0047 0.0155 0.5976
Echinococcus multilocularis insulin receptor 0.0135 0.0474 0.125
Mycobacterium ulcerans thioesterase TesA 0.0008 0.0015 0.0014
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0013 0.0033 0.0149
Schistosoma mansoni cathepsin D (A01 family) 0.0068 0.0232 0.104
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.0047 0.0155 0.0695
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0004 0.003
Echinococcus granulosus calpain A 0.0011 0.0026 0.0114
Brugia malayi hypothetical protein 0.0315 0.1127 0.3907
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0011 0.0026 0.0088
Echinococcus granulosus L aminoadipate semialdehyde 0.0052 0.0174 0.0777
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0008 0.0016 0.0053
Giardia lamblia PHD finger protein 15 0.0013 0.0033 0.045
Entamoeba histolytica cysteine protease, putative 0.0005 0.0005 0.0059
Onchocerca volvulus 0.0011 0.0024 0.0202
Echinococcus multilocularis transcription factor Dp 1 0.001 0.0023 0.0059
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0018 0.0053 0.0454
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0037 0.0119 0.1789
Giardia lamblia Histone acetyltransferase GCN5 0.0011 0.0024 0.031
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0005 0.0003 0.0004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0059 0.0199 0.0524
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0043
Brugia malayi Bromodomain containing protein 0.0014 0.0037 0.0124
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0116
Schistosoma mansoni steroid hormone receptor ad4bp 0.0005 0.0006 0.0025
Schistosoma mansoni coup transcription factor 0.0005 0.0006 0.0025
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0005 0.0004 0.003
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0008 0.0014 0.0034
Entamoeba histolytica cysteine protease, putative 0.0005 0.0005 0.0059
Echinococcus granulosus lamin dm0 0.0022 0.0067 0.0297
Loa Loa (eye worm) hypothetical protein 0.0004 0.0001 0.0002
Echinococcus granulosus ecdysone induced protein 78C 0.0005 0.0006 0.0021
Onchocerca volvulus 0.0045 0.0149 0.1309
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0037 0.0119 0.041
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0008 0.0013 0.0033
Schistosoma mansoni calpain C (C02 family) 0.0011 0.0026 0.0118
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0018 0.0052 0.0235
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0013 0.0034 0.1296
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0017 0.0046 0.0398
Schistosoma mansoni calpain-7 (C02 family) 0.0011 0.0026 0.0118
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0013 0.0032 0.0106
Schistosoma mansoni alpha-glucosidase 0.0064 0.0219 0.0981
Brugia malayi Integrin beta pat-3 precursor 0.0037 0.0118 0.0406
Echinococcus multilocularis lysosomal alpha glucosidase 0.0075 0.0256 0.0675
Mycobacterium tuberculosis Probable lipase LipD 0.0014 0.0035 0.0033
Brugia malayi hypothetical protein 0.0067 0.0227 0.0783
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0007 0.0012 0.0424
Schistosoma mansoni phosphatidylserine receptor 0.0004 0.0001 0.0004
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0045 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0007 0.0011 0.0094
Brugia malayi cathepsin L-like precursor 0.0007 0.0011 0.0036
Onchocerca volvulus 0.0315 0.1127 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0032 0.0102 0.0457
Leishmania major histone deacetylase, putative 0.0075 0.0259 0.0894
Mycobacterium leprae Polyketide synthase Pks13 0.0015 0.0038 0.0083
Treponema pallidum sodium- and chloride- dependent transporter 0.0045 0.0149 0.0324
Plasmodium falciparum acyl-CoA synthetase 0.0011 0.0026 0.0962
Echinococcus multilocularis dnaJ subfamily B 0.0111 0.0388 0.1024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0042 0.0364
Trichomonas vaginalis histone deacetylase, putative 0.006 0.0201 0.178
Leishmania major C-8 sterol isomerase-like protein 0.08 0.2883 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0012 0.0028 0.1068
Loa Loa (eye worm) hypothetical protein 0.0078 0.0269 0.0929
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0037 0.0119 1
Plasmodium falciparum plasmepsin X 0.0005 0.0005 0.0171
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0013 0.0034 0.0116
Brugia malayi Protein kinase domain containing protein 0.0075 0.0256 0.0884
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0015 0.0039 0.1492
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0016 0.0043 0.0371
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0037 0.0119 0.041
Onchocerca volvulus Prolyl endopeptidase homolog 0.0032 0.0101 0.0887
Trypanosoma brucei C-8 sterol isomerase, putative 0.08 0.2883 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0011 0.0027 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0016 0.0043 0.0371
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0005 0.0004 0.0163
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0005 0.0006 0.0021
Giardia lamblia Nitric oxide synthase, inducible 0.0012 0.0029 0.0383
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0108 0.0283
Loa Loa (eye worm) histone deacetylase 3 0.006 0.0201 0.0695
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0053 0.0178 0.0796
Loa Loa (eye worm) hypothetical protein 0.0315 0.1127 0.3907
Brugia malayi prolyl oligopeptidase family protein 0.0032 0.0101 0.0348
Plasmodium falciparum plasmepsin VI 0.0023 0.0069 0.2647
Trypanosoma brucei DNA polymerase kappa, putative 0.0005 0.0002 0.0003
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0014 0.0035 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0027 0.0229
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0007 0.0012 0.0038
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0011 0.0026 0.0088
Mycobacterium ulcerans beta-lactamase 0.0014 0.0035 0.0033
Echinococcus multilocularis histone deacetylase 3 0.006 0.0201 0.053
Plasmodium vivax histone deacetylase, putative 0.0031 0.0097 0.3722

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 29.9 nM Binding affinity towards sigma 1 receptor was determined in guinea pig brain membrane using [3H]-(+)-pentazocine as radioligand ChEMBL. 8295220
Ki (binding) = 29.9 nM Binding affinity towards sigma 1 receptor was determined in guinea pig brain membrane using [3H]-(+)-pentazocine as radioligand ChEMBL. 8295220
Ki (binding) = 183.3 nM Binding affinity towards sigma 2 receptor was determined in rat liver membrane using [3H]-DTG as radioligand in presence of dextrallorphan ChEMBL. 8295220
Ratio (binding) = 0.61 Relative binding to sigma-2 and sigma-1 type receptors, ratio of Ki ChEMBL. 8295220
Ratio (binding) = 0.61 Relative binding to sigma-2 and sigma-1 type receptors, ratio of Ki ChEMBL. 8295220

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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