Detailed information for compound 209114

Basic information

Technical information
  • TDR Targets ID: 209114
  • Name: (3,4-dichlorophenyl)-[4-(3,4-dichlorophenyl)- 4-hydroxy-1-methylpiperidin-3-yl]methanone
  • MW: 433.156 | Formula: C19H17Cl4NO2
  • H donors: 1 H acceptors: 2 LogP: 5.47 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1CCC(C(C1)C(=O)c1ccc(c(c1)Cl)Cl)(O)c1ccc(c(c1)Cl)Cl
  • InChi: 1S/C19H17Cl4NO2/c1-24-7-6-19(26,12-3-5-15(21)17(23)9-12)13(10-24)18(25)11-2-4-14(20)16(22)8-11/h2-5,8-9,13,26H,6-7,10H2,1H3
  • InChiKey: NQHSMRHMUBKGPZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (3,4-dichlorophenyl)-[4-(3,4-dichlorophenyl)-4-hydroxy-1-methyl-3-piperidyl]methanone
  • (3,4-dichlorophenyl)-[4-(3,4-dichlorophenyl)-4-hydroxy-1-methyl-3-piperidinyl]methanone
  • (3,4-dichlorophenyl)-[4-(3,4-dichlorophenyl)-4-hydroxy-1-methyl-piperidin-3-yl]methanone

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 3 Starlite/ChEMBL References
Rattus norvegicus Serotonin transporter Starlite/ChEMBL References
Rattus norvegicus Norepinephrine transporter Starlite/ChEMBL References
Rattus norvegicus Dopamine transporter Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 579 aa 35.1 %
Plasmodium vivax hypothetical protein, conserved Serotonin transporter   630 aa 528 aa 21.2 %
Plasmodium yoelii hypothetical protein Norepinephrine transporter   597 aa 478 aa 19.7 %
Neospora caninum sodium-dependent transporter, putative Norepinephrine transporter   597 aa 507 aa 30.4 %
Toxoplasma gondii Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 508 aa 32.7 %
Schistosoma japonicum ko:K05042 solute carrier family 6 (neurotransmitter transporter, glycine),, putative Norepinephrine transporter   597 aa 501 aa 39.7 %
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative Norepinephrine transporter   597 aa 579 aa 22.1 %
Onchocerca volvulus Norepinephrine transporter   597 aa 570 aa 38.6 %
Echinococcus granulosus sodium and chloride dependent glycine Norepinephrine transporter   597 aa 529 aa 42.5 %
Schistosoma mansoni sodium/chloride dependent transporter Norepinephrine transporter   597 aa 534 aa 41.0 %
Onchocerca volvulus Norepinephrine transporter   597 aa 540 aa 46.3 %
Brugia malayi Sodium:neurotransmitter symporter family protein solute carrier family 6 (neurotransmitter transporter), member 3 620 aa 579 aa 33.2 %
Drosophila melanogaster CG13796 gene product from transcript CG13796-RD Norepinephrine transporter   597 aa 569 aa 24.8 %
Onchocerca volvulus Norepinephrine transporter   597 aa 548 aa 24.8 %
Echinococcus multilocularis sodium and chloride dependent glycine Norepinephrine transporter   597 aa 507 aa 38.9 %
Onchocerca volvulus Norepinephrine transporter   597 aa 554 aa 38.6 %
Loa Loa (eye worm) hypothetical protein Norepinephrine transporter   597 aa 551 aa 25.0 %
Onchocerca volvulus Transmembrane protein 120 homolog Norepinephrine transporter   597 aa 577 aa 34.0 %
Schistosoma mansoni sodium/chloride dependent transporter Norepinephrine transporter   597 aa 529 aa 41.6 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 595 aa 34.0 %
Schistosoma japonicum ko:K05046 solute carrier family 6 (neurotransmitter transporter, GABA), member, putative Norepinephrine transporter   597 aa 545 aa 41.7 %
Echinococcus multilocularis sodium and chloride dependent glycine Norepinephrine transporter   597 aa 529 aa 42.0 %
Onchocerca volvulus High affinity copper uptake protein 1 homolog Norepinephrine transporter   597 aa 551 aa 47.4 %
Plasmodium vivax amine transporter, putative Norepinephrine transporter   597 aa 483 aa 21.1 %
Brugia malayi Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 581 aa 34.6 %
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter Norepinephrine transporter   597 aa 549 aa 41.9 %
Echinococcus granulosus sodium and chloride dependent glycine Norepinephrine transporter   597 aa 507 aa 38.9 %
Drosophila melanogaster CG1698 gene product from transcript CG1698-RA Norepinephrine transporter   597 aa 513 aa 38.4 %
Plasmodium knowlesi transporter, putative Serotonin transporter   630 aa 514 aa 20.2 %
Toxoplasma gondii Sodium:neurotransmitter symporter family protein Norepinephrine transporter   597 aa 522 aa 22.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus uncharacterized sodium dependent transporter 0.1447 0.1418 0.1418
Onchocerca volvulus 0.0038 0.0022 0.0016
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0021 0.0843
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0038 0.0022 0.0026
Loa Loa (eye worm) beta-lactamase 0.0149 0.0132 0.0132
Onchocerca volvulus 0.0038 0.0022 0.0016
Schistosoma mansoni sodium/chloride dependent transporter 0.1447 0.1418 0.1418
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Echinococcus granulosus 7tm_1 domain containing protein 0.0038 0.0022 0.0022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0066 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.001 0.001
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0012 0.0082
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0012 0.0344
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0077 0.0077
Echinococcus granulosus sodium:potassium:calcium exchanger 0.0255 0.0237 0.0237
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0022 0.0022
Brugia malayi G protein-coupled receptor F59B2.13 0.0038 0.0022 0.0026
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0001 0.0001
Schistosoma mansoni opsin-like receptor 0.0038 0.0022 0.0022
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0027 0.0147
Brugia malayi nuclear hormone receptor family member odr-7 0.0031 0.0015 0.0018
Giardia lamblia PHD finger protein 15 0.0029 0.0013 0.0647
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0149 0.0149
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0038 0.0022 0.0026
Brugia malayi tailless protein 0.0031 0.0015 0.0018
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0015 0.0018
Schistosoma mansoni hypothetical protein 0.0038 0.0022 0.0022
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0076 0.0059 0.0059
Leishmania major P-type ATPase, putative 0.0076 0.0059 0.1753
Echinococcus granulosus hypothetical protein 0.0707 0.0685 0.0685
Brugia malayi Latrophilin receptor protein 2 0.0066 0.0049 0.0058
Echinococcus granulosus FTZ F1 alpha 0.0066 0.005 0.005
Trypanosoma cruzi Replication factor A protein 1 0.0019 0.0003 0.0078
Trichomonas vaginalis set domain proteins, putative 0.0243 0.0225 0.128
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0022 0.0022
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0085 0.0068 0.5
Brugia malayi beta-lactamase family protein 0.0149 0.0132 0.0157
Brugia malayi steroid hormone receptor 0.0066 0.005 0.0059
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0069 0.0052 0.2181
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0024 0.0018
Echinococcus multilocularis Glutaredoxin protein 5 0.0049 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.089 0.0866 0.0866
Trypanosoma brucei C-8 sterol isomerase, putative 0.0357 0.0338 1
Toxoplasma gondii ABC1 family protein 0.0149 0.0132 0.0932
Onchocerca volvulus 0.0038 0.0022 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0022 0.0022
Onchocerca volvulus 0.0038 0.0022 0.0016
Echinococcus multilocularis pyruvate kinase 0.0034 0.0018 0.0018
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.1447 0.1418 0.1418
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0038 0.0038
Brugia malayi G protein-coupled receptor 0.0038 0.0022 0.0026
Trypanosoma brucei calcium-transporting ATPase, putative 0.0048 0.0032 0.0944
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0004 0.0004
Trichomonas vaginalis AGC family protein kinase 0.0076 0.006 0.0336
Schistosoma mansoni smad 0.0026 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0002 0.0002
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0039 0.0023 0.0125
Onchocerca volvulus 0.0038 0.0022 0.0016
Onchocerca volvulus 0.0038 0.0022 0.0016
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0069 0.0052 0.0293
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0021 0.0021
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0026 0.001 0.001
Echinococcus multilocularis sodium and chloride dependent glycine 0.1447 0.1418 0.1418
Brugia malayi latrophilin 2 splice variant baaae 0.0142 0.0125 0.0148
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.0132 0.075
Echinococcus granulosus beta LACTamase domain containing family member 0.0149 0.0132 0.0132
Trypanosoma brucei calcium-transporting ATPase, putative 0.0017 0.0001 0.0027
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0066 0.005 0.005
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.005 0.0033 0.0033
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0001
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0085 0.0068 0.2603
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Trypanosoma brucei hypothetical protein, conserved 0.0149 0.0132 0.3914
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0022 0.0022
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0069 0.0052 0.1547
Leishmania major C-8 sterol isomerase-like protein 0.0357 0.0338 1
Echinococcus multilocularis SAM and MBT domain containing protein 0.0146 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Brugia malayi N-terminal motif family protein 0.019 0.0172 0.0204
Echinococcus multilocularis sodium:potassium:calcium exchanger 0.0255 0.0237 0.0237
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0142 0.0125 0.0125
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0004 0.01
Trypanosoma cruzi hypothetical protein, conserved 0.0149 0.0132 0.3914
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0035 0.1461
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0011 0.0011
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0038 0.0022 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0066 0.005 0.0059
Trichomonas vaginalis AGC family protein kinase 0.0076 0.006 0.0336
Leishmania major phospholipid-transporting ATPase 1-like protein 0.0017 0.0001 0.0027
Loa Loa (eye worm) hypothetical protein 0.0741 0.0719 0.0719
Schistosoma mansoni transmemberane protein 0.0388 0.0369 0.0369
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0066 0.0049 0.0049
Schistosoma mansoni histamine h1 receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0066 0.005 0.005
Onchocerca volvulus 0.0038 0.0022 0.0016
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0578 0.0557 0.0556
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0022 0.0022
Echinococcus granulosus protein kinase C gamma type 0.0026 0.001 0.001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.1447 0.1418 0.1418
Plasmodium falciparum pyruvate kinase 0.0034 0.0018 0.0125
Echinococcus granulosus protein kinase c iota type 0.0026 0.001 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0009 0.0338
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.0028 0.0012 0.0344
Echinococcus granulosus serine/threonine protein kinase 0.0052 0.0035 0.0035
Brugia malayi Tachykinin-like peptides receptor 99D 0.0038 0.0022 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0066 0.005 0.0059
Schistosoma mansoni nuclear receptor 0.0031 0.0015 0.0015
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0001 0.0001
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0015 0.0015
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0038 0.0022 0.0022
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0018 0.0125
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0192 0.0175 0.9439
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0149 0.0132 0.0157
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0021 0.0113
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0009 0.0338
Loa Loa (eye worm) hypothetical protein 0.0066 0.005 0.005
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0076 0.0059 0.0059
Echinococcus granulosus sodium:potassium:calcium exchanger 6 0.0255 0.0237 0.0237
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0013 0.0089
Schistosoma mansoni thyroid hormone receptor 0.0066 0.005 0.005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0081 0.0081
Brugia malayi hypothetical protein 0.0038 0.0022 0.0026
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0004 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.001 0.001
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0048 0.0032 0.0032
Brugia malayi hypothetical protein 0.0038 0.0022 0.0026
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0025 0.0025
Trypanosoma brucei phospholipid-translocating P-type ATPase (flippase), putative 0.0017 0.0001 0.0027
Brugia malayi MH2 domain containing protein 0.0026 0.001 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Brugia malayi hypothetical protein 0.0038 0.0022 0.0026
Brugia malayi E1-E2 ATPase family protein 0.0045 0.0028 0.0033
Echinococcus multilocularis ecdysone induced protein 78C 0.0066 0.005 0.005
Loa Loa (eye worm) nuclear receptor NHR-67 0.0031 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0182 0.0165 0.0165
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0062 0.0046 0.0046
Echinococcus multilocularis protein kinase c epsilon type 0.0026 0.001 0.001
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0203 0.0185 0.0185
Echinococcus multilocularis geminin 0.071 0.0687 0.0687
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.1447 0.1418 0.1418
Brugia malayi replication factor A 73 kDa subunit 0.0039 0.0023 0.0027
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0038 0.0022 0.0022
Echinococcus multilocularis dna polymerase eta 0.002 0.0004 0.0004
Schistosoma mansoni DNA polymerase eta 0.002 0.0004 0.0004
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0076 0.0059 0.0059
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.001 0.005
Echinococcus multilocularis nervana 2 0.0388 0.0369 0.0369
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0038 0.1115
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0008
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.005 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Echinococcus granulosus microtubule associated protein 2 0.1441 0.1412 0.1412
Brugia malayi cytoplasmic intermediate filament protein 0.0062 0.0046 0.0054
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0038 0.0022 0.0022
Brugia malayi CHD4 protein 0.0017 0.0001 0.0001
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0069 0.0052 0.2181
Schistosoma mansoni hypothetical protein 0.071 0.0687 0.0687
Plasmodium vivax cation/H+ antiporter, putative 0.0255 0.0237 0.1671
Trypanosoma brucei glucosidase, putative 0.0037 0.0021 0.0611
Loa Loa (eye worm) hypothetical protein 0.0208 0.019 0.019
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0076 0.0059 0.0417
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0019
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0066 0.005 0.005
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.001 0.001
Echinococcus granulosus tachykinin peptides receptor 99D 0.0038 0.0022 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.001 0.001
Echinococcus multilocularis pyruvate kinase 0.0034 0.0018 0.0018
Brugia malayi nuclear receptor NHR-88 0.0066 0.005 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0031 0.0015 0.0008
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0021 0.0021
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0013 0.0013
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0018 0.0011
Brugia malayi ecdysteroid receptor 0.0066 0.005 0.0059
Echinococcus granulosus histone acetyltransferase MYST2 0.0166 0.0149 0.0149
Schistosoma mansoni cpg binding protein 0.0062 0.0046 0.0046
Schistosoma mansoni hypothetical protein 0.0066 0.0049 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0004 0.0123
Brugia malayi Cytochrome P450 family protein 0.0024 0.0008 0.0009
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0066 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0149 0.0132 0.0132
Schistosoma mansoni serine/threonine-protein kinase 0.0052 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0066 0.005 0.005
Echinococcus granulosus lamin dm0 0.0116 0.0099 0.0099
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0055 0.0039 0.0419
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.1447 0.1418 0.1418
Trypanosoma cruzi hypothetical protein, conserved 0.0149 0.0132 0.3914
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0069 0.0052 0.0293
Echinococcus multilocularis nuclear receptor nhr 48 0.0031 0.0015 0.0015
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0135 0.0118 0.0118
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0066 0.005 0.005
Echinococcus granulosus replication protein A 70 kDa DNA binding 0.0039 0.0023 0.0023
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0015 0.0015
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0022 0.0022
Echinococcus granulosus 7TM GPCR rhodopsin 0.0038 0.0022 0.0022
Echinococcus multilocularis lamin 0.0116 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0388 0.0369 0.0369
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Mycobacterium tuberculosis Probable ionic transporter integral membrane protein ChaA 0.0255 0.0237 0.2546
Brugia malayi GnHR receptor homolog 0.0038 0.0022 0.0026
Echinococcus multilocularis orexin receptor type 2 0.0038 0.0022 0.0022
Echinococcus multilocularis G-protein coupled receptor, putative 0.0038 0.0022 0.0022
Echinococcus multilocularis allatostatin A receptor 0.0038 0.0022 0.0022
Echinococcus granulosus phospholipid transporting ATPase IF 0.0017 0.0001 0.0001
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0055 0.0039 0.0419
Loa Loa (eye worm) serotonin transporter b 0.8524 0.843 0.843
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0069 0.0052 0.0293
Plasmodium falciparum calcium-transporting ATPase 0.0076 0.0059 0.0417
Brugia malayi MAP kinase sur-1 0.0054 0.0038 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0066 0.005 0.0059
Echinococcus multilocularis beta LACTamase domain containing family member 0.0149 0.0132 0.0132
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0031 0.0015 0.0018
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.1447 0.1418 0.1418
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0066 0.0049 0.0058
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.1447 0.1418 0.1418
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0008 0.0228
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0025 0.0009 0.0044
Brugia malayi Na,K-ATPase alpha subunit 0.0199 0.0182 0.0215
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0026 0.001 0.001
Mycobacterium ulcerans esterase/lipase LipP 0.0149 0.0132 0.7108
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0038 0.1115
Brugia malayi nuclear hormone receptor family member nhr-6 0.0031 0.0015 0.0018
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.1447 0.1418 0.1418
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0066 0.005 0.005
Echinococcus granulosus fmrfamide receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus multilocularis smad 0.0026 0.001 0.001
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0076 0.0059 0.1753
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0066 0.005 0.005
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0038 0.1115
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0022 0.0022
Schistosoma mansoni replication factor A 1 rfa1 0.0039 0.0023 0.0023
Schistosoma mansoni biogenic amine receptor 0.0038 0.0022 0.0022
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0031 0.0015 0.0446
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0048 0.0032 0.0038
Loa Loa (eye worm) latrophilin receptor protein 2 0.0066 0.0049 0.0049
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.0116 0.0116
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0018 0.0011
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0002 0.0002
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0001 0.0008
Echinococcus granulosus neuropeptide receptor A26 0.0038 0.0022 0.0022
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0055 0.0306
Schistosoma mansoni hypothetical protein 0.0066 0.0049 0.0049
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.019 0.0172 0.0194
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0022 0.0022
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0022 0.0022
Brugia malayi follicle stimulating hormone receptor 0.0038 0.0022 0.0026
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0069 0.0052 0.0293
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0019 0.0003 0.001
Trichomonas vaginalis AGC family protein kinase 0.0076 0.006 0.0336
Loa Loa (eye worm) hypothetical protein 0.0066 0.005 0.005
Onchocerca volvulus 0.0149 0.0132 0.0147
Loa Loa (eye worm) hypothetical protein 0.0056 0.004 0.004
Echinococcus multilocularis phospholipid transporting ATPase IA 0.0017 0.0001 0.0001
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0388 0.0369 0.0369
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0004 0.0123
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0038 0.0022 0.0026
Schistosoma mansoni ATPase 0.0069 0.0052 0.0052
Schistosoma mansoni neuropeptide receptor 0.0038 0.0022 0.0022
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0076 0.006 0.0336
Echinococcus multilocularis FTZ F1 alpha 0.0066 0.005 0.005
Plasmodium vivax amine transporter, putative 0.1447 0.1418 1
Loa Loa (eye worm) hypothetical protein 0.8524 0.843 0.843
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0004 0.0123
Echinococcus granulosus nervana 2 0.0388 0.0369 0.0369
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0015 0.0015
Giardia lamblia Kinase, AGC PKA 0.005 0.0033 0.1785
Loa Loa (eye worm) hypothetical protein 0.0066 0.005 0.005
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0011 0.0011
Onchocerca volvulus 0.0388 0.0369 0.0428
Echinococcus granulosus intermediate filament protein 0.0116 0.0099 0.0099
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0038 0.0022 0.0026
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0038 0.0021 0.0021
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0018 0.0191
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.1447 0.1418 0.1418
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0066 0.005 0.0059
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0009 0.0338
Loa Loa (eye worm) E1-E2 ATPase 0.0038 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0255 0.0237 0.0237
Echinococcus granulosus chromobox protein 1 0.0071 0.0055 0.0054
Mycobacterium tuberculosis Conserved protein 0.0149 0.0132 0.142
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0015 0.0015
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0022 0.0022
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0027 0.0021
Onchocerca volvulus 0.0038 0.0022 0.0016
Onchocerca volvulus Bile acid receptor homolog 0.0066 0.005 0.0049
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0026 0.001 0.001
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0013 0.0089
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0002 0.0002
Giardia lamblia DINP protein human, muc B family 0.002 0.0004 0.018
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0004 0.0004
Schistosoma mansoni peptidase Clp (S14 family) 0.0085 0.0068 0.0068
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0069 0.0052 0.2839
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0066 0.005 0.005
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.0068 0.3592
Loa Loa (eye worm) AGC/NDR protein kinase 0.0026 0.001 0.001
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0017 0.0001 0.0027
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0021 0.0024
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.1447 0.1418 0.1418
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.0008
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0004 0.0019
Loa Loa (eye worm) hypothetical protein 0.0074 0.0058 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0255 0.0237 0.1349
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0004 0.0123
Echinococcus granulosus cpg binding protein 0.0068 0.0051 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0066 0.005 0.0059
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0004 0.0004
Trypanosoma cruzi rac serine-threonine kinase, putative 0.005 0.0033 0.0982
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0388 0.0369 0.0369
Echinococcus multilocularis chromobox protein 1 0.0071 0.0055 0.0054
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0001
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0001 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0021 0.0611
Onchocerca volvulus Sodium\/potassium\/calcium exchanger 0.0255 0.0237 0.0271
Echinococcus granulosus sodium and chloride dependent glycine 0.1447 0.1418 0.1418
Onchocerca volvulus 0.0038 0.0022 0.0016
Brugia malayi Hr1 repeat family protein 0.0026 0.001 0.0011
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0038 0.0022 0.0022
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0035 0.0019 0.0019
Loa Loa (eye worm) transcription factor SMAD2 0.0379 0.036 0.036
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1447 0.1418 0.1418
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0076 0.0059 0.0059
Brugia malayi Serotonin receptor 0.0484 0.0464 0.055
Brugia malayi mbt repeat family protein 0.0146 0.0129 0.0152
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0019
Brugia malayi hypothetical protein 0.0035 0.0019 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0004 0.0123
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0066 0.005 0.005
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0022 0.0022
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0009 0.0338
Brugia malayi Heterochromatin protein 1 0.0071 0.0055 0.0065
Echinococcus multilocularis calcium transporting atpase 0.0076 0.0059 0.0059
Echinococcus multilocularis lamin dm0 0.0116 0.0099 0.0099
Echinococcus multilocularis dnaJ subfamily B 0.0886 0.0862 0.0862
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0081 0.0081
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0149 0.0132 0.0132
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Echinococcus multilocularis musashi 0.0116 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.1447 0.1418 0.1418
Schistosoma mansoni hypothetical protein 0.071 0.0687 0.0687
Brugia malayi Dopamine receptor 0.0038 0.0022 0.0026
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0022 0.0022
Brugia malayi Sodium/calcium exchanger protein 0.4044 0.3991 0.4734
Mycobacterium leprae conserved hypothetical protein 0.0149 0.0132 0.5414
Entamoeba histolytica hypothetical protein 0.0041 0.0025 0.1025
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0076 0.0059 0.1753
Loa Loa (eye worm) hypothetical protein 0.0388 0.0369 0.0369
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0016 0.0016
Schistosoma mansoni phospholipid-transporting atpase 0.0017 0.0001 0.0001
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0069 0.0052 0.1547
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0004 0.0123
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0038 0.0022 0.0026
Onchocerca volvulus 0.0149 0.0132 0.0147
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.019 0.0172 0.0172
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0004 0.0004
Brugia malayi PHD-finger family protein 0.0029 0.0013 0.0015
Onchocerca volvulus 0.8524 0.843 1
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0074 0.0058 0.0058
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0024 0.0024
Schistosoma mansoni neuropeptide f receptor 76f 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0048 0.0032 0.0032
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0021 0.0113
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0009 0.0252
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0066 0.005 0.0059
Echinococcus granulosus peptidase Clp S14 family 0.0055 0.0039 0.0039
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0066 0.005 0.0049
Schistosoma mansoni neuropeptide receptor 0.0038 0.0022 0.0022
Schistosoma mansoni potassium-dependent sodium-calcium exchanger 3 4 0.0255 0.0237 0.0237
Brugia malayi hypothetical protein 0.0038 0.0022 0.0026
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0018 0.0407
Onchocerca volvulus 0.0038 0.0022 0.0016
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0026 0.001 0.001
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0038 0.0021 0.063
Trypanosoma cruzi phospholipid-translocating ATPase, putative 0.0017 0.0001 0.0027
Schistosoma mansoni potassium-dependent sodium-calcium exchanger 3 4 0.0255 0.0237 0.0237
Schistosoma mansoni hypothetical protein 0.0038 0.0022 0.0022
Trypanosoma brucei phospholipid-translocating ATPase, putative 0.0017 0.0001 0.0027
Echinococcus multilocularis rac serine:threonine kinase 0.0052 0.0035 0.0035
Echinococcus multilocularis serine:threonine protein kinase N2 0.0026 0.001 0.001
Brugia malayi calcium ATPase 0.0038 0.0022 0.0026
Loa Loa (eye worm) Smad1 0.0026 0.001 0.001
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.00000484 0.0001
Echinococcus granulosus ecdysone induced protein 78C 0.0066 0.005 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.001 0.001
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0004 0.0044
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0255 0.0237 0.0237
Brugia malayi Membrane calcium atpase protein 3 0.0076 0.0059 0.007
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0118 0.0118
Schistosoma mansoni biogenic amine receptor 0.0038 0.0022 0.0022
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0203 0.0185 0.5479
Brugia malayi G-protein coupled receptor 0.0038 0.0022 0.0026
Schistosoma mansoni steroid hormone receptor ad4bp 0.0066 0.005 0.005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.001 0.005
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0076 0.0059 0.3113
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.001 0.001
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0077 0.0077
Echinococcus granulosus dna polymerase eta 0.002 0.0004 0.0004
Brugia malayi Bromodomain containing protein 0.0031 0.0015 0.0018
Schistosoma mansoni hypothetical protein 0.0038 0.0022 0.0022
Echinococcus multilocularis nervana 2 0.0437 0.0417 0.0417
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0013 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0033 0.0033
Leishmania major aminophospholipid translocase, putative 0.0017 0.0001 0.0027
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0038 0.0038
Plasmodium vivax calcium-transporting ATPase, putative 0.0076 0.0059 0.0417
Brugia malayi Steroid receptor seven-up type 2 0.0066 0.005 0.0059
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0081 0.0081
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0022 0.0022
Schistosoma mansoni biogenic amine receptor 0.0038 0.0022 0.0022
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0015 0.0015
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0019 0.0022
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0038 0.0265
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0026 0.001 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.001 0.001
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0013 0.0013
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1447 0.1418 0.1682
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0009 0.0338
Schistosoma mansoni serine/threonine-protein kinase 0.0052 0.0035 0.0035
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0027 0.0147
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0031 0.0015 0.0015
Mycobacterium ulcerans hypothetical protein 0.0149 0.0132 0.7108
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0038 0.021
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.005 0.0033 0.0234
Onchocerca volvulus 0.1447 0.1418 0.1673
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0578 0.0557 0.0556
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0004 0.0123
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0069 0.0052 0.2839
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0031 0.0015 0.0015
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0038 0.0038
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0055 0.0039 0.1337
Echinococcus multilocularis dna polymerase kappa 0.002 0.0004 0.0004
Brugia malayi MH1 domain containing protein 0.0026 0.001 0.0011
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0038 0.0022 0.0022
Brugia malayi MH1 domain containing protein 0.0026 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0022 0.0022
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0038 0.0022 0.0026
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0357 0.0338 0.0338
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0009 0.0252
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0001 0.0001
Schistosoma mansoni coup transcription factor 0.0066 0.005 0.005
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0055 0.0306
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.1447 0.1418 1
Leishmania major pyruvate kinase 0.0034 0.0018 0.0527
Echinococcus multilocularis pyruvate kinase 0.0027 0.0011 0.0011
Mycobacterium tuberculosis Conserved protein 0.0149 0.0132 0.142
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0203 0.0185 0.0185
Schistosoma mansoni hypothetical protein 0.0255 0.0237 0.0237
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0066 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0116 0.0099 0.0099
Echinococcus granulosus sodium and chloride dependent glycine 0.1447 0.1418 0.1418
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0022 0.0022
Brugia malayi putative neuropeptide receptor 0.0038 0.0022 0.0026
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.0008
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0018 0.0527
Loa Loa (eye worm) DR-78 0.0031 0.0015 0.0015
Echinococcus multilocularis polycomb protein SCMH1 0.0146 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0791 0.0768 0.0768
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0038 0.0022 0.0022
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0076 0.0059 0.2475
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0066 0.005 0.005
Trichomonas vaginalis AGC family protein kinase 0.0026 0.001 0.005
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.00000484 0.0001
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.00000484 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0066 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0011 0.0011
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.001 0.005
Echinococcus multilocularis neuropeptide receptor A26 0.0038 0.0022 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0066 0.005 0.005
Schistosoma mansoni serine/threonine kinase 0.0026 0.001 0.001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0001 0.0014
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0026 0.001 0.001
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0022 0.0022
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.0019 0.0019
Leishmania major cytochrome p450-like protein 0.0024 0.0008 0.0228
Echinococcus multilocularis sodium calcium exchanger 1.0109 1 1
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0172 0.0154 0.0183
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0021 0.0113
Loa Loa (eye worm) phospholipid-transporting ATPase ID 0.0017 0.0001 0.0001
Echinococcus multilocularis sodium and chloride dependent glycine 0.1447 0.1418 0.1418
Onchocerca volvulus 0.0151 0.0134 0.0149
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0009 0.0091
Loa Loa (eye worm) hypothetical protein 0.0066 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0066 0.0049 0.0049
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0004 0.0005
Mycobacterium tuberculosis Probable lipase LipE 0.0149 0.0132 0.142
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0004 0.0123
Loa Loa (eye worm) MBCTL1 0.0166 0.0149 0.0149
Toxoplasma gondii P-type ATPase PMA1 0.0038 0.0021 0.015
Schistosoma mansoni smad1 5 8 and 0.0026 0.001 0.001
Leishmania major P-type H -ATPase, putative 0.0038 0.0021 0.063
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.1447 0.1418 0.1418
Plasmodium vivax replication protein A1, large subunit, putative 0.0019 0.0003 0.0018
Echinococcus granulosus SAM and MBT domain containing protein 0.0146 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Leishmania major replication factor A, 51kDa subunit, putative 0.0019 0.0003 0.0078
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0004 0.0123
Echinococcus granulosus jumonji domain containing protein 0.004 0.0024 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0022 0.0022
Trypanosoma brucei Replication factor A protein 1 0.0019 0.0003 0.0078
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0001 0.0014
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0149 0.0132 0.0132
Mycobacterium ulcerans aldehyde dehydrogenase 0.0203 0.0185 1
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0017 0.0001 0.0027
Brugia malayi Nuclear hormone receptor-like 1 0.0066 0.005 0.0059
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0069 0.0052 0.1547
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0118 0.0118
Schistosoma mansoni pyruvate kinase 0.0034 0.0018 0.0018
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0004 0.0005
Mycobacterium tuberculosis Probable esterase LipL 0.0149 0.0132 0.142
Brugia malayi neuropeptide F receptor 0.0038 0.0022 0.0026
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0038 0.021
Echinococcus granulosus thyroid hormone receptor alpha 0.0031 0.0015 0.0015
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0012 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0002 0.0007
Brugia malayi sulfakinin receptor protein 0.0038 0.0022 0.0026
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0437 0.0417 0.0417
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Echinococcus multilocularis protein kinase c iota type 0.0026 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Chlamydia trachomatis pyruvate kinase 0.0034 0.0018 0.0109
Loa Loa (eye worm) hypothetical protein 0.0034 0.0018 0.0018
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0024 0.0024
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0066 0.005 0.0059
Schistosoma mansoni hypothetical protein 0.0886 0.0862 0.0862
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0013 0.0091
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0001 0.0009
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0146 0.0129 0.0143
Echinococcus granulosus nuclear receptor nhr 48 0.0031 0.0015 0.0015
Onchocerca volvulus 0.0192 0.0175 0.0197
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0001 0.0014
Brugia malayi nuclear hormone receptor 0.0066 0.005 0.0059
Loa Loa (eye worm) hypothetical protein 0.0166 0.0149 0.0149
Toxoplasma gondii hypothetical protein 0.1447 0.1418 1
Toxoplasma gondii aldehyde dehydrogenase 0.0203 0.0185 0.1304
Loa Loa (eye worm) hypothetical protein 0.0028 0.0011 0.0011
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0076 0.0059 0.0059
Trypanosoma cruzi Protein kinase B 0.0052 0.0035 0.1043
Plasmodium falciparum phospholipid-transporting ATPase, putative 0.0017 0.0001 0.0006
Mycobacterium ulcerans beta-lactamase 0.0149 0.0132 0.7108
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0022 0.0022
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0076 0.0059 0.0417
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0018 0.0011
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0388 0.0369 0.0369
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0066 0.005 0.005
Loa Loa (eye worm) calcium ATPase 0.0038 0.0022 0.0022
Plasmodium falciparum replication protein A1, large subunit 0.0019 0.0003 0.0018
Schistosoma mansoni sex comb on midleg homolog 0.0146 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0066 0.0049 0.0049
Brugia malayi RNA binding protein 0.0135 0.0118 0.014
Onchocerca volvulus 0.0038 0.0022 0.0016
Schistosoma mansoni survival motor neuron protein 0.0151 0.0134 0.0134
Trichomonas vaginalis cation-transporting ATPase, putative 0.0038 0.0021 0.0116
Brugia malayi Calcitonin receptor-like protein seb-1 0.0208 0.019 0.0226
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0001
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0076 0.0059 0.1753
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0022 0.0022
Onchocerca volvulus Neuropeptide F receptor homolog 0.0038 0.0022 0.0016
Leishmania major DNA polymerase eta, putative 0.002 0.0004 0.0123
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0035 0.0019 0.0019
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0004 0.0004
Plasmodium vivax P-type ATPase4, putative 0.0076 0.0059 0.0417
Trypanosoma brucei phospholipid-transporting ATPase 1-like protein, putative 0.0017 0.0001 0.0027
Plasmodium falciparum phd finger protein, putative 0.0029 0.0013 0.0089
Schistosoma mansoni bromodomain containing protein 0.007 0.0053 0.0053
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) mbt repeat family protein 0.0146 0.0129 0.0129
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0024 0.0024
Brugia malayi larval opioid receptor 0.0038 0.0022 0.0026
Echinococcus granulosus survival motor neuron protein 1 0.0741 0.0719 0.0719
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0118 0.0118
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0021 0.0113
Echinococcus granulosus histone lysine methyltransferase setb 0.005 0.0033 0.0033
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.1447 0.1418 0.1682
Onchocerca volvulus 0.0116 0.0099 0.0108
Onchocerca volvulus 0.0038 0.0022 0.0016
Schistosoma mansoni pyruvate kinase 0.0034 0.0018 0.0018
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0085 0.0068 0.0068
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0015 0.0015
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0116 0.0099 0.0099
Echinococcus granulosus serotonin transporter 0.8524 0.843 0.843
Leishmania major pyruvate kinase 0.0034 0.0018 0.0527
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0081 0.0081
Loa Loa (eye worm) AGC/PKN protein kinase 0.0026 0.001 0.001
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0076 0.0059 0.007
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0022 0.0022
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0081 0.0081
Trypanosoma cruzi P-type H+-ATPase, putative 0.0038 0.0021 0.063
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0009 0.0338
Echinococcus granulosus lamin 0.0116 0.0099 0.0099
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0166 0.0149 0.0149
Toxoplasma gondii hypothetical protein 0.0029 0.0013 0.0091
Loa Loa (eye worm) hypothetical protein 0.1447 0.1418 0.1418
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.005 0.0033 0.0234
Brugia malayi Smad1 0.0026 0.001 0.0011
Echinococcus granulosus protein kinase c epsilon type 0.0026 0.001 0.001
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0118 0.0118
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0002 0.0002
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.0068 0.0479
Toxoplasma gondii manganese resistance 1 protein, putative 0.0255 0.0237 0.1671
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0066 0.005 0.005
Brugia malayi beta-lactamase family protein 0.0149 0.0132 0.0157
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0022 0.0022
Echinococcus multilocularis survival motor neuron protein 1 0.0741 0.0719 0.0719
Loa Loa (eye worm) hypothetical protein 0.0054 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0012 0.0064
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0004 0.0044
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0018 0.0018
Mycobacterium leprae Probable ionic transporter integral membrane protein ChaA 0.0255 0.0237 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0021 0.0113
Loa Loa (eye worm) steroid hormone receptor 0.0066 0.005 0.005
Echinococcus granulosus serine:threonine protein kinase N2 0.0026 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0013
Schistosoma mansoni sodium/chloride dependent transporter 0.1448 0.1419 0.1419
Echinococcus granulosus dro:myosuppressin receptor 0.0038 0.0022 0.0022
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0038 0.0022 0.0022
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0022 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0066 0.005 0.005
Schistosoma mansoni aldehyde dehydrogenase 0.0203 0.0185 0.0185
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0038 0.0038
Schistosoma mansoni amine GPCR 0.0038 0.0022 0.0022
Brugia malayi jmjC domain containing protein 0.0094 0.0077 0.0092
Trichomonas vaginalis penicillin-binding protein, putative 0.0149 0.0132 0.075
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0022 0.0022
Echinococcus granulosus uncharacterized sodium dependent transporter 0.1447 0.1418 0.1418
Mycobacterium tuberculosis Probable lipase LipD 0.0149 0.0132 0.142
Schistosoma mansoni amine GPCR 0.0038 0.0022 0.0022
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0022 0.0022
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0437 0.0417 0.0417
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0166 0.0149 0.0149
Trichomonas vaginalis AGC family protein kinase 0.0026 0.001 0.005
Schistosoma mansoni opsin-like receptor 0.0038 0.0022 0.0022
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0002 0.0016
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0024 0.0024
Brugia malayi K+-dependent Na+/Ca+ exchanger related-protein 0.0255 0.0237 0.0281
Loa Loa (eye worm) norepinephrine transporter 0.8524 0.843 0.843
Echinococcus multilocularis Smad4 0.0026 0.001 0.001
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0019 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0076 0.006 0.0336
Echinococcus multilocularis replication protein A 70 kDa DNA binding 0.0039 0.0023 0.0023
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.0068 0.3592
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0004 0.0004
Echinococcus granulosus pyruvate kinase 0.0034 0.0018 0.0018
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.1447 0.1418 1
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0001
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0038 0.0022 0.0016
Onchocerca volvulus 0.0791 0.0768 0.0902
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0019
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0038 0.0021 0.015
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.1447 0.1418 1
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0022 0.0022
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0004 0.0146
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Brugia malayi phospholipid-translocating P-type ATPase, flippase family protein 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0024 0.0024
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0166 0.0149 0.0149
Schistosoma mansoni Smad4 0.0026 0.001 0.001
Brugia malayi Sodium:neurotransmitter symporter family protein 0.8524 0.843 1
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0069 0.0052 0.2181
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0066 0.005 0.0059
Schistosoma mansoni hypothetical protein 0.0142 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus multilocularis serotonin receptor 0.0038 0.0022 0.0022
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0009 0.001
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0008 0.0008
Brugia malayi AKH receptor 0.0038 0.0022 0.0026
Onchocerca volvulus 0.0031 0.0015 0.0008
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0172 0.0154 0.0154
Echinococcus multilocularis tar DNA binding protein 0.0135 0.0118 0.0118
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0035 0.1461
Echinococcus multilocularis serine threonine protein kinase 0.0026 0.001 0.001
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0013 0.0091
Trichomonas vaginalis penicillin-binding protein, putative 0.0149 0.0132 0.075
Schistosoma mansoni hypothetical protein 0.0151 0.0134 0.0134
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0022 0.0022
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0001 0.0008
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0026 0.001 0.001
Schistosoma mansoni retinoic acid receptor RXR 0.0066 0.005 0.005
Brugia malayi beta-lactamase 0.0149 0.0132 0.0157
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0038 0.0022 0.0022
Mycobacterium tuberculosis Conserved protein 0.0149 0.0132 0.142
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0022 0.0022
Brugia malayi Dopamine receptor protein 2 0.0038 0.0022 0.0026
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0022 0.0022
Echinococcus granulosus g protein coupled receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0114 0.0097 0.0097
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0069 0.0052 0.1547
Loa Loa (eye worm) hypothetical protein 0.4044 0.3991 0.3991
Onchocerca volvulus 0.0062 0.0046 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0021 0.0611
Echinococcus multilocularis thyroid hormone receptor alpha 0.0066 0.005 0.005
Trypanosoma brucei rac serine-threonine kinase, putative 0.0076 0.006 0.177
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0045 0.0028 0.1164
Entamoeba histolytica hypothetical protein 0.0041 0.0025 0.1025
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0016 0.011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0013 0.0089
Echinococcus granulosus nervana 2 0.0437 0.0417 0.0417
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0018 0.0527
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0066 0.005 0.0059
Loa Loa (eye worm) replication factor A 73 kDa subunit 0.0039 0.0023 0.0023
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0021 0.0021
Echinococcus granulosus nervana 2 0.0388 0.0369 0.0369
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0018 0.0097
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0004 0.0123
Giardia lamblia Pyruvate kinase 0.0034 0.0018 0.0935
Schistosoma mansoni phospholipid-transporting atpase 0.0017 0.0001 0.0001
Echinococcus granulosus sex peptide receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.005 0.0033 0.0033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0001 0.0014
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0021 0.0145
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.014 0.0123 0.0123
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0076 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0066 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.1447 0.1418 0.1418
Loa Loa (eye worm) melatonin receptor type 1A 0.0038 0.0022 0.0022
Brugia malayi neuropeptide F receptor 0.0038 0.0022 0.0026
Leishmania major DNA polymerase kappa, putative 0.002 0.0004 0.0123
Brugia malayi Cytochrome P450 family protein 0.0054 0.0038 0.0045
Echinococcus granulosus polycomb protein SCMH1 0.0146 0.0129 0.0129
Brugia malayi hypothetical protein 0.0038 0.0022 0.0026
Echinococcus multilocularis serotonin transporter 0.8524 0.843 0.843
Brugia malayi nuclear receptor RXR 0.0035 0.0019 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0022 0.0022
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0001
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0199 0.0182 0.0182
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0038 0.0022 0.0022
Schistosoma mansoni neuropeptide receptor 0.0038 0.0022 0.0022
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0022 0.0022
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0068 0.0479
Brugia malayi Serotonin receptor 0.0038 0.0022 0.0026
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0955 0.093 1
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0069 0.0052 0.0293
Treponema pallidum hypothetical protein 0.0255 0.0237 0.0266
Trypanosoma brucei protein kinase, putative 0.0054 0.0038 0.1115
Schistosoma mansoni thyroid hormone receptor 0.0066 0.005 0.005
Onchocerca volvulus 0.1447 0.1418 0.1673
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0022 0.0022
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0076 0.0059 0.0059
Mycobacterium ulcerans aldehyde dehydrogenase 0.0203 0.0185 1
Brugia malayi MH2 domain containing protein 0.0379 0.036 0.0427
Entamoeba histolytica protein kinase, putative 0.0076 0.006 0.2499
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0038 0.1115
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1447 0.1418 0.1682
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0149 0.0132 0.7108
Schistosoma mansoni chromobox protein 0.0071 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0066 0.005 0.005
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0021 0.0113
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0002 0.0025
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.0068 0.0479
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.001 0.005
Onchocerca volvulus 0.0066 0.005 0.0049
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0388 0.0369 0.0369
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.001 0.001
Onchocerca volvulus 0.0038 0.0022 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0255 0.0237 0.1349
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0033 0.0033
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0076 0.0059 0.0059
Brugia malayi Protein kinase domain containing protein 0.0026 0.001 0.0011
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0009 0.033
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0022 0.0006 0.0006
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0059 0.0333
Brugia malayi Pre-SET motif family protein 0.0032 0.0016 0.0018
Echinococcus granulosus calcium transporting atpase 0.0076 0.0059 0.0059
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.0068 0.0464
Mycobacterium leprae Probable lipase LipE 0.0149 0.0132 0.5414
Brugia malayi hypothetical protein 0.0028 0.0012 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0022 0.0022
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0009 0.0091
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0069 0.0052 0.1547
Schistosoma mansoni intermediate filament proteins 0.0116 0.0099 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0004 0.0123
Toxoplasma gondii P-type ATPase4, putative 0.0076 0.0059 0.0417
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0011 0.0011
Echinococcus multilocularis nervana 2 0.0437 0.0417 0.0417
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0058 0.0058
Schistosoma mansoni type V p-type atpase isoform 0.0017 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0029 0.0013 0.0013
Schistosoma mansoni chromobox protein 0.0071 0.0055 0.0055
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0076 0.0059 0.0059
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0056 0.004 0.004
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0085 0.0068 0.0479
Trichomonas vaginalis cation-transporting ATPase, putative 0.0069 0.0052 0.0293
Onchocerca volvulus 0.1447 0.1418 0.1673
Echinococcus multilocularis sodium:potassium:calcium exchanger 6 0.0255 0.0237 0.0237
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.0388 0.0369 0.0369
Brugia malayi Protein kinase domain containing protein 0.0076 0.006 0.0071
Echinococcus granulosus smad 0.0026 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0066 0.005 0.0059
Brugia malayi mbt repeat family protein 0.0146 0.0129 0.0152
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0016 0.0016
Brugia malayi Intermediate filament tail domain containing protein 0.0116 0.0099 0.0118
Echinococcus granulosus dnaJ subfamily B 0.0886 0.0862 0.0862
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0056 0.004 0.004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0022 0.0022
Echinococcus granulosus Glutaredoxin protein 5 0.0049 0.0032 0.0032
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.1447 0.1418 0.1418
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Brugia malayi RNA recognition motif domain containing protein 0.0135 0.0118 0.014
Leishmania major phospholipid-translocating P-type ATPase (flippase), putative 0.0017 0.0001 0.0027
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0018 0.0018
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0008 0.0291
Brugia malayi Protein kinase domain containing protein 0.0026 0.001 0.0011
Schistosoma mansoni pyruvate kinase 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus granulosus serine threonine protein kinase nrc 0.005 0.0033 0.0033
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0146 0.0129 0.0129
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0001
Trichomonas vaginalis esterase, putative 0.0149 0.0132 0.075
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0012 0.0082
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.001 0.001
Brugia malayi nuclear receptor NHR-67 0.0031 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0066 0.005 0.005
Onchocerca volvulus Huntingtin homolog 0.014 0.0123 0.0136
Trichomonas vaginalis cation-transporting ATPase, putative 0.0069 0.0052 0.0293
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0199 0.0182 1
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0012 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0066 0.005 0.0059
Echinococcus granulosus pyruvate kinase 0.0034 0.0018 0.0018
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0076 0.0059 0.0417
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0038 0.0021 0.0025
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus granulosus g protein coupled receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0022 0.0022
Brugia malayi conserved hypotetical protein 0.0031 0.0015 0.0018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.001 0.005
Entamoeba histolytica protein kinase, putative 0.0074 0.0058 0.2412
Brugia malayi hypothetical protein 0.0038 0.0022 0.0026
Echinococcus granulosus geminin 0.071 0.0687 0.0687
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0022 0.0022
Loa Loa (eye worm) RNA binding protein 0.0135 0.0118 0.0118
Echinococcus multilocularis somatostatin receptor 0.0038 0.0022 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0149 0.0132 0.0932
Schistosoma mansoni opsin-like receptor 0.0038 0.0022 0.0022
Echinococcus multilocularis phospholipid transporting atpase ih phospholipid transporting atpase if 0.0017 0.0001 0.0001
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0149 0.0149
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0026 0.001 0.001
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0001 0.0009
Onchocerca volvulus Huntingtin homolog 0.014 0.0123 0.0136
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0085 0.0068 0.0068
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0021 0.0113
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0066 0.0049 0.0049
Loa Loa (eye worm) MH2 domain-containing protein 0.0379 0.036 0.036
Brugia malayi nuclear receptor RXR 0.0031 0.0015 0.0018
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0018 0.0021
Onchocerca volvulus 0.0243 0.0225 0.0257
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0048 0.0032 0.0944
Entamoeba histolytica phospholipid-transporting ATPase IA, putative 0.0017 0.0001 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0038 0.0038
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0388 0.0369 0.0369
Schistosoma mansoni cpg binding protein 0.0068 0.0051 0.0051
Entamoeba histolytica protein kinase, putative 0.0026 0.001 0.0377
Loa Loa (eye worm) transbilayer Amphipath transporters family member 0.0017 0.0001 0.0001
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.001 0.001
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.0008 0.0293
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0018 0.0527
Echinococcus multilocularis serotonin receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) AGC/AKT protein kinase 0.0076 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0066 0.0049 0.0049
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0038 0.0038
Echinococcus multilocularis GPCR, family 2 0.0066 0.0049 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0024 0.0129
Brugia malayi orphan nuclear receptor NR2E1 0.0031 0.0015 0.0018
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0069 0.0052 0.0052
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0038 0.0022 0.0022
Schistosoma mansoni nuclear receptor nhr-48 0.0031 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus granulosus allatostatin A receptor 0.0038 0.0022 0.0022
Brugia malayi Melatonin receptor type 1A 0.0038 0.0022 0.0026
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0004 0.0123
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0076 0.0059 0.0059
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0021 0.0611
Echinococcus granulosus peptide allatostatin:somatostatin 0.0038 0.0022 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0004 0.0123
Brugia malayi ecdysone receptor 0.0031 0.0015 0.0018
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0012 0.0344
Echinococcus multilocularis serine:threonine protein kinase 38 0.0026 0.001 0.001
Trypanosoma brucei calcium-translocating P-type ATPase 0.0076 0.0059 0.1753
Schistosoma mansoni alpha-1 adrenergic receptor 0.0038 0.0022 0.0022
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.0068 0.0464
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0024 0.0129
Onchocerca volvulus 0.0038 0.0022 0.0016
Brugia malayi nuclear receptor NHR-88 0.0031 0.0015 0.0018
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0388 0.0369 0.0369
Onchocerca volvulus 0.0096 0.0079 0.0084
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0118 0.0118
Schistosoma mansoni atypical protein kinase C 0.0026 0.001 0.001
Leishmania major hypothetical protein, conserved 0.0149 0.0132 0.3914
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0203 0.0185 0.1988
Loa Loa (eye worm) hypothetical protein 0.8524 0.843 0.843
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0004 0.0123
Toxoplasma gondii hypothetical protein 0.1447 0.1418 1
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0059 0.0333
Echinococcus granulosus Protein kinase C brain isozyme 0.0026 0.001 0.001
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0069 0.0052 0.0368
Schistosoma mansoni smad1 5 8 and 0.0026 0.001 0.001
Brugia malayi Bromodomain containing protein 0.004 0.0024 0.0028
Brugia malayi Probable ClpP-like protease 0.0085 0.0068 0.0081
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0021 0.0843
Echinococcus granulosus zinc finger protein 0.0024 0.0008 0.0008
Echinococcus multilocularis dro:myosuppressin receptor 0.0038 0.0022 0.0022
Brugia malayi hypothetical protein 0.0791 0.0768 0.0911
Treponema pallidum sodium- and chloride- dependent transporter 0.8524 0.843 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0038 0.0022 0.0022
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0009 0.001
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.0035 0.0019 0.0012
Echinococcus granulosus chromobox protein 1 0.0071 0.0055 0.0054
Echinococcus granulosus orexin receptor type 2 0.0038 0.0022 0.0022
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0208 0.019 0.019
Leishmania major calcium-transporting ATPase, putative 0.0076 0.0059 0.1753
Echinococcus multilocularis chromobox protein 1 0.0071 0.0055 0.0054
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0015 0.0015
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.8524 0.843 0.843
Brugia malayi hypothetical protein 0.0038 0.0022 0.0026
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Schistosoma mansoni sodium/chloride dependent transporter 0.8524 0.843 0.843
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0199 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0018 0.0018
Schistosoma mansoni ATPase 0.0069 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0124 0.0107 0.0107
Onchocerca volvulus Alhambra homolog 0.0029 0.0013 0.0005
Brugia malayi hypothetical protein 0.0038 0.0022 0.0026
Plasmodium vivax phospholipid-transporting ATPase, putative 0.0017 0.0001 0.0006
Echinococcus multilocularis conserved hypothetical protein 0.0669 0.0647 0.0647
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0021 0.0113
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Schistosoma mansoni microtubule-associated protein tau 0.1441 0.1412 0.1412
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0022 0.0022
Plasmodium vivax SET domain protein, putative 0.0032 0.0016 0.011
Schistosoma mansoni sodium/calcium exchanger 1.0109 1 1
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0026 0.001 0.001
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0199 0.0182 0.0182
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0004 0.0123
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0013 0.0013
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0038 0.1115
Plasmodium falciparum cation/H+ antiporter 0.0255 0.0237 0.1671
Brugia malayi Na/Ca eXchangers family member (ncx-4) 0.0255 0.0237 0.0281
Brugia malayi chromobox protein homolog 3 0.004 0.0024 0.0028
Loa Loa (eye worm) nuclear hormone receptor 0.0031 0.0015 0.0015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.001 0.005
Mycobacterium ulcerans hypothetical protein 0.0025 0.0009 0.0338
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0015 0.0015
Trichomonas vaginalis AGC family protein kinase 0.0076 0.006 0.0336
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus granulosus g protein coupled receptor 0.0038 0.0022 0.0022
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.005 0.005
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0022 0.0022
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.0081 0.0096
Toxoplasma gondii replication factor-a protein 1 (rpa1) subfamily protein 0.0019 0.0003 0.0018
Onchocerca volvulus 0.0038 0.0022 0.0016
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0081 0.0081
Onchocerca volvulus 0.0031 0.0015 0.0008
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0031 0.0015 0.0015
Loa Loa (eye worm) TYRA-2 protein 0.0038 0.0022 0.0022
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0012 0.0344
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0038 0.1115
Echinococcus multilocularis G protein coupled receptor 139 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0019
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.1447 0.1418 0.1418
Loa Loa (eye worm) hypothetical protein 0.0149 0.0132 0.0132
Echinococcus multilocularis cpg binding protein 0.0068 0.0051 0.0051
Echinococcus multilocularis serine:threonine protein kinase N2 0.0026 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0069 0.0052 0.0052
Echinococcus granulosus neuropeptide FF receptor 2 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0134 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.1447 0.1418 0.1418
Brugia malayi calcium ATPase 0.0038 0.0021 0.0025
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0004 0.0019
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0066 0.0049 0.0049
Echinococcus granulosus nervana 2 0.0437 0.0417 0.0417
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Schistosoma mansoni amine GPCR 0.0038 0.0022 0.0022
Echinococcus multilocularis histone acetyltransferase MYST2 0.0166 0.0149 0.0149
Schistosoma mansoni lamin 0.0116 0.0099 0.0099
Brugia malayi hypothetical protein 0.1447 0.1418 0.1682
Loa Loa (eye worm) hypothetical protein 0.0146 0.0129 0.0129
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0069 0.0052 0.1547
Echinococcus granulosus neuropeptide receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.1447 0.1418 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0022 0.0022
Trypanosoma brucei unspecified product 0.002 0.0004 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0255 0.0237 0.1349
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0076 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Loa Loa (eye worm) CYP4Cod1 0.0024 0.0008 0.0008
Echinococcus granulosus somatostatin receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0066 0.005 0.005
Brugia malayi protein kinase C II. 0.0026 0.001 0.0011
Brugia malayi photoreceptor-specific nuclear receptor 0.0066 0.005 0.0059
Leishmania major calcium motive p-type ATPase, putative 0.0076 0.0059 0.1753
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0008 0.0228
Brugia malayi jmjC domain containing protein 0.004 0.0024 0.0029
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.0388 0.0369 0.0369
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.0132 0.075
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0037 0.0021 0.0114
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0025 0.0025
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0018 0.0097
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Schistosoma mansoni nuclear receptor 0.0031 0.0015 0.0015
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0388 0.0369 0.0369
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0004 0.0123
Loa Loa (eye worm) hypothetical protein 0.0085 0.0068 0.0068
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0149 0.0132 0.142
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0046 0.0046
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0031 0.0015 0.0015
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0012 0.0082
Onchocerca volvulus 0.0043 0.0027 0.0022
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0004 0.0123
Schistosoma mansoni alpha-glucosidase 0.0143 0.0126 0.0126
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0013 0.0013
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0022 0.0022
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0031 0.0015 0.0015
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0031 0.0015 0.0607
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0038 0.0022 0.0022
Echinococcus granulosus neuropeptide receptor 0.0038 0.0022 0.0022
Schistosoma mansoni amine GPCR 0.0038 0.0022 0.0022
Echinococcus multilocularis phospholipid transporting ATPase IF 0.0017 0.0001 0.0001
Loa Loa (eye worm) solute carrier family 8 1.0109 1 1
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0069 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0155 0.0138 0.0138
Brugia malayi putative neuropeptide receptor NPR1 0.0038 0.0022 0.0026
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0069 0.0052 0.1547
Schistosoma mansoni sex comb on midleg homolog 0.0146 0.0129 0.0129
Schistosoma mansoni myosin xvIII 0.0038 0.0022 0.0022
Echinococcus granulosus phospholipid transporting atpase ih 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0018 0.0527
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0004 0.0123
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.005 0.0033 0.0033
Echinococcus granulosus Smad4 0.0026 0.001 0.001
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0055 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0066 0.005 0.005
Echinococcus granulosus peregrin 0.0031 0.0015 0.0015
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1447 0.1418 0.1682
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0038 0.0022 0.0022
Schistosoma mansoni na/ca exchanger 0.0255 0.0237 0.0237
Brugia malayi hypothetical protein 0.0041 0.0025 0.003
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.1447 0.1418 0.1418
Echinococcus granulosus GPCR family 2 0.0066 0.0049 0.0049
Loa Loa (eye worm) intermediate filament protein 0.0116 0.0099 0.0099
Schistosoma mansoni hypothetical protein 0.0038 0.0022 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.001 0.005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.8524 0.843 0.843
Entamoeba histolytica protein kinase 2, putative 0.005 0.0033 0.1374
Loa Loa (eye worm) histone methyltransferase 0.002 0.0004 0.0004
Echinococcus multilocularis peptidase Clp (S14 family) 0.0055 0.0039 0.0039
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0041 0.0025 0.1237
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0021 0.0113
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0022 0.0022
Echinococcus multilocularis peregrin 0.0031 0.0015 0.0015
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Brugia malayi hypothetical protein 0.0038 0.0022 0.0026
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0214 0.0196 0.0196
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0149 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.004 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0054 0.0038 0.0038
Plasmodium falciparum transporter, putative 0.1447 0.1418 1
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0022 0.0022
Onchocerca volvulus 0.0038 0.0022 0.0016
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0149 0.0132 0.0132
Onchocerca volvulus 0.0038 0.0022 0.0016
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0255 0.0237 0.0237
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0009 0.033
Echinococcus granulosus lysosomal alpha glucosidase 0.0166 0.0149 0.0149
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0038 0.0038
Trichomonas vaginalis alpha-L-fucosidase, putative 0.1783 0.1751 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.0027 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Echinococcus granulosus serotonin receptor 0.0038 0.0022 0.0022
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0019 0.0019
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0035 0.0019 0.0019
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0048 0.0032 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Echinococcus multilocularis neuropeptide s receptor 0.0038 0.0022 0.0022
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0012 0.0082
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0038 0.0021 0.063
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.00000484 0.0001
Loa Loa (eye worm) hypothetical protein 0.0066 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus multilocularis neuropeptide FF receptor 2 0.0038 0.0022 0.0022
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0038 0.0022 0.0901
Brugia malayi TAR-binding protein 0.0135 0.0118 0.014
Loa Loa (eye worm) TAR-binding protein 0.0135 0.0118 0.0118
Schistosoma mansoni neuropeptide receptor 0.0038 0.0022 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0081 0.0081
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0038 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0041 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.014 0.0123 0.0123
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0068 0.0065
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.001 0.001
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0038 0.0022 0.0022
Mycobacterium tuberculosis Probable hydrolase 0.0149 0.0132 0.142
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0038 0.021
Loa Loa (eye worm) hypothetical protein 0.0149 0.0132 0.0132
Schistosoma mansoni smad1 5 8 and 0.0026 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni adenoreceptor 0.0038 0.0022 0.0022
Schistosoma mansoni alpha glucosidase 0.0037 0.0021 0.0021
Brugia malayi intermediate filament protein 0.0116 0.0099 0.0118
Brugia malayi hypothetical protein 0.0038 0.0022 0.0026
Plasmodium falciparum amino acid transporter, putative 0.1447 0.1418 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Schistosoma mansoni RAR-like nuclear receptor 0.0066 0.005 0.005
Brugia malayi hypothetical protein 0.0031 0.0015 0.0018
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0052 0.0035 0.1043
Brugia malayi hypothetical protein 0.0741 0.0719 0.0852
Loa Loa (eye worm) hypothetical protein 0.0035 0.0019 0.0019
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.001 0.005
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0004 0.0123
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.0008
Trichomonas vaginalis AGC family protein kinase 0.0026 0.001 0.005
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0038 0.0022 0.0022
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0022 0.0022
Onchocerca volvulus 0.0146 0.0129 0.0143
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0013 0.0013
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0008 0.0008
Echinococcus granulosus phospholipid transporting ATPase IA 0.0017 0.0001 0.0001
Brugia malayi hypothetical protein 0.0035 0.0019 0.0022
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0038 0.0022 0.0022
Entamoeba histolytica sodium/calcium exchanger protein, putative 0.0255 0.0237 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.005 0.005
Trypanosoma cruzi P-type H+-ATPase, putative 0.0038 0.0021 0.063
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0038 0.0022 0.0022
Schistosoma mansoni growth hormone secretagogue receptor 0.0038 0.0022 0.0022
Giardia lamblia Pyruvate kinase 0.0017 0.0001 0.0027
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.00000484 0.00000484
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0208 0.019 0.0226
Trichomonas vaginalis cation-transporting ATPase, putative 0.0069 0.0052 0.0293
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0066 0.005 0.005
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0009 0.033
Schistosoma mansoni zinc finger protein 0.0031 0.0015 0.0015
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0076 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.1447 0.1418 0.1418
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.00000484 0.0001
Loa Loa (eye worm) solute carrier family 6 member 4 0.8524 0.843 0.843
Plasmodium vivax hypothetical protein, conserved 0.1447 0.1418 1
Schistosoma mansoni myelin transcription factor 1 myt1 0.0166 0.0149 0.0149
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.1447 0.1418 0.1418
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Echinococcus multilocularis microtubule associated protein 2 0.1441 0.1412 0.1412
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0151 0.0134 0.0159
Echinococcus granulosus G protein coupled receptor 139 0.0038 0.0022 0.0022
Mycobacterium ulcerans aldehyde dehydrogenase 0.0203 0.0185 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0022 0.0022
Onchocerca volvulus Protein ultraspiracle homolog 0.0066 0.005 0.0049
Entamoeba histolytica phospholipid-transporting ATPase Neo1, putative 0.0017 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.1447 0.1418 0.1418
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0009 0.001
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0029 0.0013 0.0196
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0021 0.0021
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.0081 0.0081
Onchocerca volvulus 0.0149 0.0132 0.0147
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0038 0.1115
Brugia malayi RE15519p 0.0038 0.0022 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.001 0.001
Brugia malayi G-protein coupled receptor 0.0038 0.0022 0.0026
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0041 0.0025 0.0267
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0025 0.0025
Trypanosoma brucei cytochrome P450, putative 0.0024 0.0008 0.0228
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0199 0.0182 0.0182
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0066 0.005 0.005
Brugia malayi hypothetical protein 0.0031 0.0015 0.0018
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.0132 0.075
Leishmania major calcium-translocating P-type ATPase 0.0069 0.0052 0.1547
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Schistosoma mansoni lamin 0.0116 0.0099 0.0099
Entamoeba histolytica protein kinase, putative 0.0076 0.006 0.2499
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0039 0.0023 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0066 0.005 0.0059
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0066 0.005 0.005
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0069 0.0052 0.1547
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0003 0.0013
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0357 0.0338 1
Echinococcus multilocularis nervana 2 0.0388 0.0369 0.0369
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0043 0.0043
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0009 0.0252
Echinococcus granulosus dna polymerase kappa 0.002 0.0004 0.0004
Trypanosoma brucei P-type H+-ATPase, putative 0.0038 0.0021 0.063
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0031 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0049 0.0033 0.0033
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0015 0.0008
Schistosoma mansoni zinc finger protein 0.0024 0.0008 0.0008
Toxoplasma gondii AGC kinase 0.0074 0.0058 0.0407
Brugia malayi PHD-finger family protein 0.003 0.0014 0.0016
Echinococcus granulosus alpha 1A adrenergic receptor 0.0038 0.0022 0.0022
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0001 0.0009
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0018 0.0847
Loa Loa (eye worm) Na/Ca eXchangers family member 0.0255 0.0237 0.0237
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0199 0.0182 0.0182
Entamoeba histolytica hypothetical protein 0.0041 0.0025 0.1025
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0026 0.001 0.001
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0018 0.0125
Onchocerca volvulus 0.0116 0.0099 0.0108
Mycobacterium ulcerans lipase LipD 0.0149 0.0132 0.7108
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0004 0.0004
Brugia malayi MH2 domain containing protein 0.0026 0.001 0.0011
Onchocerca volvulus 0.0388 0.0369 0.0428
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0165 0.0147 0.6083
Brugia malayi Pre-SET motif family protein 0.0214 0.0196 0.0232
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2542 0.2503 0.2503
Echinococcus granulosus NDR protein kinase 0.0026 0.001 0.001
Trypanosoma brucei P-type H+-ATPase, putative 0.0038 0.0021 0.063
Schistosoma mansoni nuclear hormone receptor 0.0066 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0149 0.0132 0.0132
Trypanosoma cruzi P-type H+-ATPase, putative 0.0038 0.0021 0.063
Echinococcus multilocularis g-protein coupled receptor 0.0038 0.0022 0.0022
Brugia malayi CXXC zinc finger family protein 0.0062 0.0046 0.0054
Echinococcus granulosus g-protein coupled receptor 0.0038 0.0022 0.0022
Brugia malayi Cytochrome P450 family protein 0.0024 0.0008 0.0009
Echinococcus multilocularis sex peptide receptor 0.0038 0.0022 0.0022
Trichomonas vaginalis alpha-L-fucosidase, putative 0.1783 0.1751 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0121 0.0104 0.0736
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0066 0.005 0.0059
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1447 0.1418 0.1418
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0004 0.0123
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0149 0.0132 0.142
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0166 0.0149 0.0176
Brugia malayi nuclear hormone receptor 0.0031 0.0015 0.0018
Schistosoma mansoni aldehyde dehydrogenase 0.0203 0.0185 0.0185
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0026 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0026 0.001 0.001
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0388 0.0369 0.0369
Brugia malayi Bromodomain containing protein 0.0082 0.0066 0.0078
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0015 0.0018
Brugia malayi Dopamine receptor protein 1 0.0038 0.0022 0.0026
Schistosoma mansoni sodium-dependent amino acid transporter 0.1447 0.1418 0.1418
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0149 0.0132 0.142
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0149 0.0132 0.0132
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0006 0.0006
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0066 0.005 0.005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0066 0.005 0.005
Brugia malayi ORL1-like opioid receptor 0.0038 0.0022 0.0026
Echinococcus granulosus neuropeptide s receptor 0.0038 0.0022 0.0022
Brugia malayi hypothetical protein 0.014 0.0123 0.0146
Brugia malayi p70 ribosomal S6 kinase beta 0.0074 0.0058 0.0068
Leishmania major P-type H -ATPase, putative 0.0038 0.0021 0.063
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0038 0.021
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0035 0.0019 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0022 0.0022
Echinococcus multilocularis zinc finger protein 0.0024 0.0008 0.0008
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0038 0.2033
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0066 0.005 0.005
Echinococcus granulosus tar DNA binding protein 0.0135 0.0118 0.0118
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0009 0.0338
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0076 0.0059 0.0059
Echinococcus granulosus Na:K ATPase alpha subunit 0.0199 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0043 0.0026 0.0026
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0066 0.0049 0.0049
Brugia malayi Glycosyl hydrolases family 31 protein 0.0166 0.0149 0.0176
Entamoeba histolytica hypothetical protein 0.0041 0.0025 0.1025
Loa Loa (eye worm) hypothetical protein 0.004 0.0024 0.0024
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0357 0.0338 0.04
Schistosoma mansoni alpha-glucosidase 0.0143 0.0126 0.0126
Trichomonas vaginalis AGC family protein kinase 0.0076 0.006 0.0336
Schistosoma mansoni amine GPCR 0.0038 0.0022 0.0022
Schistosoma mansoni cpg binding protein 0.0068 0.0051 0.0051

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 10.9 nM Binding Affinity to cocaine site of dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]-mazindol . ChEMBL. 10669562
Ki (binding) = 10.9 nM Binding Affinity to cocaine site of dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]-mazindol . ChEMBL. 10669562
Ki (binding) = 51 nM Inhibition of [3H]-DA Uptake at dopamine transporter in rat cortex was measured by liquid scintillation spectrometry ChEMBL. 10669562
Ki (binding) = 51 nM Inhibition of [3H]-DA Uptake at dopamine transporter in rat cortex was measured by liquid scintillation spectrometry ChEMBL. 10669562
Ki (binding) = 177 nM Compound was tested for Inhibition of [3H]-NE Uptake in rat parietal/occipital cortex ChEMBL. 10669562
Ki (binding) = 177 nM Compound was tested for Inhibition of [3H]-NE Uptake in rat parietal/occipital cortex ChEMBL. 10669562
Ki (binding) = 2380 nM Compound was tested for Inhibition of [3H]-5-HT Uptake in rat mid brain. ChEMBL. 10669562
Ki (binding) = 2380 nM Compound was tested for Inhibition of [3H]-5-HT Uptake in rat mid brain. ChEMBL. 10669562

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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