Detailed information for compound 255352

Basic information

Technical information
  • TDR Targets ID: 255352
  • Name: 2-(1-benzyl-2-ethyl-3-oxamoylindol-4-yl)oxyac etic acid
  • MW: 380.394 | Formula: C21H20N2O5
  • H donors: 2 H acceptors: 4 LogP: 2.75 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1c(C(=O)C(=O)N)c2c(n1Cc1ccccc1)cccc2OCC(=O)O
  • InChi: 1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)
  • InChiKey: BHLXTPHDSZUFHR-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 2-(1-benzyl-2-ethyl-3-oxamoyl-indol-4-yl)oxyacetic acid
  • 2-[(1-benzyl-2-ethyl-3-oxamoyl-4-indolyl)oxy]acetic acid
  • 2-[2-ethyl-3-oxamoyl-1-(phenylmethyl)indol-4-yl]oxyethanoic acid
  • varespladib
  • 2-[2-ethyl-3-oxamoyl-1-(phenylmethyl)indol-4-yl]oxyacetic acid
  • 2-[[2-ethyl-3-oxamoyl-1-(phenylmethyl)-4-indolyl]oxy]acetic acid
  • 2-[1-(benzyl)-2-ethyl-3-oxamoyl-indol-4-yl]oxyacetic acid
  • Varespladib [INN]
  • Acetic acid, ((3-(aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl)oxy)-,
  • LY315920

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens phospholipase A2, group IID Starlite/ChEMBL References
Sus scrofa Phospholipase A2 group 1B Starlite/ChEMBL References
Homo sapiens phospholipase A2, group IIF Starlite/ChEMBL References
Homo sapiens phospholipase A2, group V Starlite/ChEMBL References
Mus musculus phospholipase A2, group IIA (platelets, synovial fluid) Starlite/ChEMBL References
Mus musculus phospholipase A2, group IIE Starlite/ChEMBL References
Homo sapiens phospholipase A2, group X Starlite/ChEMBL References
Mus musculus phospholipase A2, group IID Starlite/ChEMBL References
Homo sapiens phospholipase A2, group IIE Starlite/ChEMBL References
Homo sapiens phospholipase A2, group IB (pancreas) Starlite/ChEMBL References
Mus musculus phospholipase A2, group V Starlite/ChEMBL References
Mus musculus phospholipase A2, group IB, pancreas Starlite/ChEMBL References
Mus musculus phospholipase A2, group IIF Starlite/ChEMBL References
Mus musculus phospholipase A2, group X Starlite/ChEMBL References
Homo sapiens phospholipase A2, group IIA (platelets, synovial fluid) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Onchocerca volvulus Phospholipase A2 homolog Get druggable targets OG5_133218 All targets in OG5_133218
Onchocerca volvulus Phospholipase A2 homolog Get druggable targets OG5_134661 All targets in OG5_134661
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_134661 All targets in OG5_134661
Brugia malayi Phospholipase A2 family protein Get druggable targets OG5_133218 All targets in OG5_133218
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133218 All targets in OG5_133218
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Phospholipase A2 family protein phospholipase A2, group IIA (platelets, synovial fluid) 144 aa 125 aa 28.0 %
Brugia malayi Phospholipase A2 family protein phospholipase A2, group IID 144 aa 121 aa 33.9 %
Brugia malayi Phospholipase A2 family protein phospholipase A2, group V 138 aa 125 aa 30.4 %
Onchocerca volvulus Phospholipase A2 group 1B   146 aa 133 aa 30.8 %
Dictyostelium discoideum hypothetical protein Phospholipase A2 group 1B   146 aa 149 aa 22.8 %
Brugia malayi Phospholipase A2 family protein phospholipase A2, group IIE 142 aa 125 aa 32.8 %
Brugia malayi Phospholipase A2 family protein phospholipase A2, group V 137 aa 125 aa 28.8 %
Trypanosoma congolense hypothetical protein, conserved Phospholipase A2 group 1B   146 aa 177 aa 22.0 %
Leishmania major hypothetical protein, conserved phospholipase A2, group IIA (platelets, synovial fluid) 146 aa 144 aa 22.9 %
Brugia malayi Phospholipase A2 family protein Phospholipase A2 group 1B   146 aa 135 aa 32.6 %
Trichomonas vaginalis conserved hypothetical protein Phospholipase A2 group 1B   146 aa 134 aa 19.4 %
Loa Loa (eye worm) hypothetical protein Phospholipase A2 group 1B   146 aa 136 aa 33.8 %
Leishmania major cell division cycle protein, putative phospholipase A2, group IID 62 aa 51 aa 31.4 %
Brugia malayi Phospholipase A2 family protein phospholipase A2, group IIE 142 aa 126 aa 31.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.001 0.0011
Echinococcus granulosus beta LACTamase domain containing family member 0.0117 0.0265 0.0599
Trypanosoma brucei presenilin-like aspartic peptidase, putative 0.0124 0.0282 0.3627
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0052 0.0095 0.0216
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0019 0.001 0.001
Loa Loa (eye worm) cytochrome P450 0.0026 0.0026 0.0034
Echinococcus granulosus ecdysone induced protein 78C 0.0026 0.0026 0.0059
Trypanosoma cruzi histone deacetylase, putative 0.0132 0.0303 0.3904
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0037 0.0049
Loa Loa (eye worm) hypothetical protein 0.0062 0.0121 0.016
Brugia malayi histone deacetylase 3 (HD3) 0.0268 0.0656 0.0952
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0046 0.0079 0.0105
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0046 0.0079 0.0094
Echinococcus granulosus beta-adrenergic receptor kinase 0.0016 0.0002 0.0004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0026 0.0026 0.0059
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0019 0.001 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0079 0.0179
Echinococcus granulosus geminin 0.0696 0.1769 0.4006
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0045 0.0077 0.0092
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0025 0.0024 0.0054
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.001 0.001
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0026 0.0026 0.0035
Leishmania major cytochrome p450-like protein 0.0026 0.0026 0.0328
Loa Loa (eye worm) hypothetical protein 0.005 0.009 0.0119
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0026 0.0026 0.0027
Trypanosoma brucei Presenilin enhancer-2 subunit of gamma secretase, putative 0.0035 0.005 0.0644
Onchocerca volvulus 0.0046 0.0079 0.0098
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0117 0.0265 0.0384
Brugia malayi GnHR receptor homolog 0.0046 0.0079 0.0115
Loa Loa (eye worm) voltage-gated potassium channel 0.0019 0.001 0.0013
Entamoeba histolytica hypothetical protein 0.0087 0.0185 0.1704
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0019 0.001 0.001
Echinococcus granulosus g protein coupled receptor 0.0046 0.0079 0.0179
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0081 0.0169 0.0662
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0046 0.0079 0.0079
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0024 0.0022 0.0088
Schistosoma mansoni dopamine-beta-monooxygenase 0.3243 0.8397 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0029 0.0034 0.0034
Schistosoma mansoni 60S ribosomal protein L21 0.0021 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0059 0.0114 0.015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0026 0.0026 0.0035
Trypanosoma brucei metacaspase MCA2 0.0045 0.0077 0.0993
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0074 0.0152 0.0201
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Schistosoma mansoni two-pore calcium channel 0.0019 0.001 0.0011
Toxoplasma gondii thioredoxin reductase 0.0126 0.0287 0.1385
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0026 0.0026 0.0471
Schistosoma mansoni voltage-gated potassium channel 0.0027 0.0029 0.0035
Echinococcus granulosus peregrin 0.0033 0.0044 0.01
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.001 0.0022
Brugia malayi mbt repeat family protein 0.0037 0.0056 0.0081
Brugia malayi Cell death protein 3 precursor 0.0107 0.0236 0.0343
Mycobacterium tuberculosis Probable reductase 0.0287 0.0706 0.3689
Schistosoma mansoni biogenic amine (5HT) receptor 0.0046 0.0079 0.0094
Echinococcus granulosus GA binding protein alpha chain 0.0057 0.0107 0.0242
Onchocerca volvulus Alhambra homolog 0.0029 0.0035 0.004
Trypanosoma cruzi histone deacetylase, putative 0.0314 0.0777 1
Trypanosoma cruzi Heat shock protein 83, putative 0.0021 0.0013 0.0161
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0212 0.0509 0.2658
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0043 0.007 0.0093
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0035 0.0049 0.0631
Echinococcus granulosus alpha 1A adrenergic receptor 0.0046 0.0079 0.0179
Echinococcus multilocularis microtubule associated protein 2 0.1022 0.2619 0.2619
Plasmodium vivax histone deacetylase 1, putative 0.0268 0.0656 0.8449
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0019 0.001 0.0022
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.004 0.0053
Echinococcus multilocularis GPCR, family 2 0.0102 0.0225 0.0225
Schistosoma mansoni hypothetical protein 0.003 0.0037 0.0044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0433 0.1086 0.4257
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0299 0.5848
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0025 0.0024 0.0024
Plasmodium falciparum importin beta, putative 0.0051 0.009 0.1162
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.015 0.035 0.0417
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0287 0.0706 0.8942
Onchocerca volvulus 0.0038 0.0059 0.0071
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0018 0.0005 0.0007
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.001 0.0022
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Leishmania major presenilin-like aspartic peptidase, putative,presenilin-like aspartic peptidase, clan AD, family A22A, putative 0.0124 0.0282 0.3627
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0043 0.007 0.0102
Entamoeba histolytica hypothetical protein 0.0087 0.0185 0.1704
Brugia malayi jmjC domain containing protein 0.0038 0.0059 0.0085
Echinococcus multilocularis potassium large conductance calcium activated 0.0019 0.001 0.001
Onchocerca volvulus Neuropeptide F receptor homolog 0.0046 0.0079 0.0098
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0323 0.0799 0.1159
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0299 0.0356
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0124 0.0282 0.1105
Trypanosoma brucei metacaspase MCA3 0.0045 0.0077 0.0993
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.001 0.0011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0433 0.1086 0.4257
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0319 0.079 0.4125
Echinococcus granulosus FTZ F1 alpha 0.0026 0.0026 0.0059
Mycobacterium tuberculosis Conserved protein 0.0117 0.0265 0.1377
Trypanosoma brucei heat shock protein, putative 0.0021 0.0013 0.0161
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0015 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0079 0.0079
Brugia malayi hypothetical protein 0.0046 0.0079 0.0115
Echinococcus multilocularis expressed conserved protein 0.0063 0.0122 0.0122
Brugia malayi Ets-domain containing protein 0.0057 0.0107 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0077 0.0303
Brugia malayi hypothetical protein 0.0037 0.0054 0.0079
Echinococcus granulosus sex peptide receptor 0.0046 0.0079 0.0179
Schistosoma mansoni hypothetical protein 0.0102 0.0225 0.0268
Echinococcus multilocularis neuropeptide receptor 0.0046 0.0079 0.0079
Brugia malayi steroid hormone receptor 0.0026 0.0026 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0002 0.0002
Echinococcus multilocularis polycomb protein SCMH1 0.0037 0.0056 0.0056
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0044 0.0073 0.0105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0026 0.0026 0.0035
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.001 0.001
Echinococcus granulosus mitogen activated protein kinase 3 0.0035 0.0049 0.0111
Loa Loa (eye worm) hypothetical protein 0.027 0.0662 0.0878
Brugia malayi PHD-finger family protein 0.0036 0.0054 0.0078
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0065 0.0065
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0025 0.0024 0.0024
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0019 0.001 0.001
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.0079 0.0179
Loa Loa (eye worm) hypothetical protein 0.2917 0.7548 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0046 0.0079 0.0179
Schistosoma mansoni gabp alpha 0.0057 0.0107 0.0127
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Schistosoma mansoni smad1 5 8 and 0.0026 0.0026 0.0031
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0059 0.0133
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0016 0.0002 0.0004
Echinococcus multilocularis voltage dependent calcium channel 0.0019 0.001 0.001
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0117 0.0265 0.1377
Plasmodium vivax glutathione reductase, putative 0.0126 0.0287 0.3687
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.1713 0.4416 0.4416
Brugia malayi putative neuropeptide receptor 0.0046 0.0079 0.0115
Giardia lamblia Kinase, CMGC MAPK 0.0035 0.0049 0.0451
Echinococcus granulosus calcium activated potassium channel 0.002 0.0011 0.0026
Brugia malayi Niemann-Pick C1 protein precursor 0.0067 0.0133 0.0193
Trichomonas vaginalis CMGC family protein kinase 0.0035 0.0049 0.0193
Trypanosoma brucei heat shock protein 90, putative 0.0021 0.0013 0.0161
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0026 0.0026 0.0125
Plasmodium falciparum metacaspase-like protein 0.0045 0.0077 0.0993
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0019 0.001 0.0011
Brugia malayi CHE-14 protein 0.0029 0.0034 0.0049
Brugia malayi RNA binding protein 0.0066 0.013 0.0189
Plasmodium vivax sentrin-specific protease 1, putative 0.0038 0.0059 0.0752
Schistosoma mansoni growth hormone secretagogue receptor 0.0046 0.0079 0.0094
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0079 0.0179
Schistosoma mansoni transient receptor potential channel 4 0.0019 0.001 0.0011
Echinococcus multilocularis heat shock protein 90 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0035
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0065 0.0148
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0016 0 0.0001
Echinococcus granulosus histone deacetylase 0.0314 0.0777 0.1759
Echinococcus granulosus histone deacetylase 7 0.0314 0.0777 0.1759
Brugia malayi Calcitonin receptor-like protein seb-1 0.0323 0.0799 0.1159
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0035
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0081 0.0169 0.0815
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0079 0.0094
Plasmodium falciparum ataxin-2 like protein, putative 0.0037 0.0054 0.0699
Schistosoma mansoni biogenic amine (5HT) receptor 0.0046 0.0079 0.0094
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0026 0.0031
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0042 0.0069 0.0069
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0079 0.0179
Echinococcus multilocularis ecdysone induced protein 78C 0.0026 0.0026 0.0026
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0046 0.0079 0.0115
Brugia malayi follicle stimulating hormone receptor 0.0046 0.0079 0.0115
Loa Loa (eye worm) hypothetical protein 0.0117 0.0265 0.0351
Echinococcus multilocularis peregrin 0.0033 0.0044 0.0044
Mycobacterium leprae conserved hypothetical protein 0.0023 0.002 0.0229
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0044 0.0073 0.1394
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.001 0.0011
Echinococcus granulosus TRP transient receptor potential channel 0.0019 0.001 0.0022
Echinococcus multilocularis FTZ F1 alpha 0.0026 0.0026 0.0026
Brugia malayi hypothetical protein 0.0043 0.0072 0.0105
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0037 0.0056 0.0715
Trypanosoma brucei heat shock protein, putative 0.0021 0.0013 0.0161
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.002 0.0094
Brugia malayi hypothetical protein 0.0046 0.0079 0.0115
Brugia malayi hypothetical protein 0.0046 0.0079 0.0115
Echinococcus multilocularis G protein coupled receptor 139 0.0046 0.0079 0.0079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0079 0.0079
Echinococcus multilocularis two pore calcium channel protein 1 0.0019 0.001 0.001
Giardia lamblia PHD finger protein 15 0.0029 0.0035 0.0324
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0079 0.0094
Trichomonas vaginalis penicillin-binding protein, putative 0.0117 0.0265 0.1038
Brugia malayi MH1 domain containing protein 0.0026 0.0026 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0175 0.0687
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Onchocerca volvulus 0.0046 0.0079 0.0098
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.001 0.0022
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0175 0.0175
Schistosoma mansoni histone deacetylase hda2 0.032 0.0793 0.0944
Loa Loa (eye worm) hypothetical protein 0.0117 0.0265 0.0351
Plasmodium falciparum ataxin-2 like protein, putative 0.0037 0.0054 0.0699
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0869 0.2221 0.3222
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0022 0.0016 0.0074
Schistosoma mansoni neuropeptide receptor 0.0046 0.0079 0.0094
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Loa Loa (eye worm) DOMON domain-containing protein 0.0328 0.0812 0.1076
Echinococcus multilocularis histone deacetylase 0.0314 0.0777 0.0777
Brugia malayi serine/threonine-protein kinase plk-2 0.0063 0.0124 0.018
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0046 0.0079 0.0115
Trypanosoma brucei heat shock protein, putative 0.0021 0.0013 0.0161
Brugia malayi mbt repeat family protein 0.0037 0.0056 0.0081
Schistosoma mansoni transcription factor LCR-F1 0.0087 0.0185 0.022
Entamoeba histolytica heat shock protein 90, putative 0.0021 0.0013 0.0117
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.002 0.0095
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0209 0.0209
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.001 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0026 0.0026 0.0125
Echinococcus granulosus short transient receptor potential channel 6 0.0019 0.001 0.0022
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0044 0.0073 0.0931
Echinococcus granulosus Smad4 0.0026 0.0026 0.0058
Onchocerca volvulus Phospholipase A2 homolog 0.2665 0.6893 0.9131
Echinococcus granulosus voltage gated potassium channel 0.0019 0.001 0.0022
Schistosoma mansoni alpha-1 adrenergic receptor 0.0046 0.0079 0.0094
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.0124 0.0487
Brugia malayi Phospholipase A2 family protein 0.2665 0.6893 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0079 0.0079
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.001 0.0022
Loa Loa (eye worm) DOMON domain-containing protein 0.0328 0.0812 0.1076
Echinococcus multilocularis lamin dm0 0.0018 0.0005 0.0005
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0087 0.0185 0.042
Echinococcus granulosus sodium channel protein 0.0279 0.0685 0.1552
Loa Loa (eye worm) bromodomain containing protein 0.0026 0.0026 0.0035
Echinococcus granulosus peptide allatostatin:somatostatin 0.0046 0.0079 0.0179
Treponema pallidum fructose-bisphosphate aldolase 0.0433 0.1086 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0051 0.009 0.1162
Echinococcus multilocularis dro:myosuppressin receptor 0.0046 0.0079 0.0079
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0044 0.0073 0.4002
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0067 0.0133 0.1225
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0015 0.0019
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.0079 0.0179
Echinococcus granulosus Nicastrin 0.006 0.0116 0.0264
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0026 0.0026 0.0471
Brugia malayi Inositol-1 0.0024 0.0022 0.0033
Schistosoma mansoni amine GPCR 0.0046 0.0079 0.0094
Schistosoma mansoni myosin xvIII 0.0046 0.0079 0.0094
Schistosoma mansoni sex comb on midleg homolog 0.0037 0.0056 0.0067
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.001 0.0011
Trypanosoma cruzi heat shock protein 85, putative 0.0021 0.0013 0.0161
Echinococcus multilocularis neuropeptide s receptor 0.0338 0.0838 0.0838
Echinococcus granulosus short transient receptor potential channel 6 0.0019 0.001 0.0022
Onchocerca volvulus 0.0046 0.0079 0.0098
Echinococcus granulosus Niemann Pick C1 protein 0.0067 0.0133 0.0301
Mycobacterium leprae Conserved hypothetical protein 0.0026 0.0026 0.0304
Schistosoma mansoni histone deacetylase 4 5 0.0314 0.0777 0.0925
Toxoplasma gondii heat shock protein HSP90 0.0021 0.0013 0.006
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0035 0.008
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.001 0.0011
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.001 0.001
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0035 0.0049 0.0631
Toxoplasma gondii histone deacetylase HDAC4 0.0132 0.0303 0.1466
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0026 0.0058
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0025 0.0024 0.0028
Trichomonas vaginalis histone deacetylase, putative 0.0268 0.0656 0.2574
Echinococcus multilocularis serotonin receptor 0.0046 0.0079 0.0079
Schistosoma mansoni zinc finger protein 0.0022 0.0017 0.002
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0019 0.001 0.0011
Toxoplasma gondii aldehyde dehydrogenase 0.0131 0.0299 0.1443
Onchocerca volvulus 0.0046 0.0079 0.0098
Trichomonas vaginalis heat shock protein, putative 0.0016 0.0002 0.0007
Plasmodium falciparum sentrin-specific protease 1 0.0038 0.0059 0.0752
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.001 0.0045
Echinococcus granulosus microtubule associated protein 2 0.1022 0.2619 0.5932
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0019 0.001 0.0014
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0043 0.0072 0.0367
Loa Loa (eye worm) inositol-1 0.0024 0.0022 0.003
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0074 0.0152 0.195
Plasmodium falciparum glutathione reductase 0.0044 0.0073 0.0931
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0026 0.0026 0.0031
Echinococcus multilocularis allatostatin A receptor 0.0046 0.0079 0.0079
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0319 0.079 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0073 0.0931
Schistosoma mansoni hypothetical protein 0.0696 0.1769 0.2106
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.002 0.0252
Schistosoma mansoni heat shock protein 0.0021 0.0013 0.0015
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0026 0.0031
Echinococcus granulosus hypothetical protein 0.0046 0.0079 0.0179
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0126 0.0286 0.034
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0026 0.0026 0.0328
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0025 0.0024 0.0028
Trypanosoma cruzi PAB1-binding protein , putative 0.0037 0.0054 0.0699
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0032 0.0042 0.0062
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.002 0.0355
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0037 0.0056 0.0715
Schistosoma mansoni lamin 0.0018 0.0005 0.0006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0223 0.054 0.0644
Schistosoma mansoni amine GPCR 0.0046 0.0079 0.0094
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.015 0.035 0.0417
Loa Loa (eye worm) heat shock protein 90 0.0021 0.0013 0.0017
Schistosoma mansoni hypothetical protein 0.0028 0.0031 0.0037
Mycobacterium tuberculosis Probable esterase LipL 0.0117 0.0265 0.1377
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0046 0.0079 0.0094
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0046 0.0079 0.0079
Brugia malayi Latrophilin receptor protein 2 0.0102 0.0225 0.0326
Mycobacterium tuberculosis Probable dehydrogenase 0.0287 0.0706 0.3689
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Onchocerca volvulus 0.0046 0.0079 0.0098
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0077 0.0993
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0026 0.0026 0.0035
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0019
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0026 0.0026 0.0026
Loa Loa (eye worm) Smad1 0.0026 0.0026 0.0034
Brugia malayi Histone deacetylase family protein 0.0314 0.0777 0.1127
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Onchocerca volvulus 0.0117 0.0265 0.0344
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0044 0.0073 0.0086
Echinococcus granulosus voltage dependent calcium channel 0.0019 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.1713 0.4416 0.585
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.002 0.0252
Trichomonas vaginalis histone deacetylase, putative 0.0268 0.0656 0.2574
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0026 0.0026 0.0026
Plasmodium vivax histone deacetylase 2, putative 0.0314 0.0777 1
Echinococcus granulosus survival motor neuron protein 1 0.0188 0.0447 0.1013
Trypanosoma brucei metacaspase 5, putative 0.0045 0.0077 0.0993
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0026 0.0026 0.0471
Loa Loa (eye worm) hypothetical protein 0.027 0.0662 0.0878
Brugia malayi hypothetical protein 0.0019 0.001 0.0014
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0102 0.0225 0.0326
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0016 0.0002 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0433 0.1086 0.4257
Brugia malayi Histone deacetylase family protein 0.0314 0.0777 0.1127
Echinococcus multilocularis serotonin receptor 0.0046 0.0079 0.0079
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0026 0.0031
Trypanosoma cruzi heat shock protein 90, putative 0.0016 0.0002 0.002
Treponema pallidum NADH oxidase 0.0044 0.0073 0.0653
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0026 0.0026 0.0038
Brugia malayi DOMON domain containing protein 0.0328 0.0812 0.1178
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0268 0.0656 0.2574
Echinococcus multilocularis ryanodine receptor 44f 0.0019 0.001 0.001
Onchocerca volvulus 0.0328 0.0812 0.107
Brugia malayi G protein-coupled receptor F59B2.13 0.0046 0.0079 0.0115
Brugia malayi latrophilin 2 splice variant baaae 0.0221 0.0533 0.0774
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0041 0.0066 0.0257
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0026 0.0026 0.0125
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0025 0.0024 0.0093
Trypanosoma brucei PAB1-binding protein , putative 0.0037 0.0054 0.0699
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0083 0.0175 0.0687
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0044 0.0073 0.0931
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0074 0.0152 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.0236 0.0313
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.001 0.0011
Brugia malayi Endoplasmin precursor 0.0021 0.0013 0.0018
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0044 0.0073 1
Echinococcus multilocularis heat shock protein 90 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Echinococcus granulosus mitogen activated protein kinase 0.0035 0.0049 0.0111
Trypanosoma cruzi histone deacetylase, putative 0.0314 0.0777 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0063 0.0124 0.1595
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0079 0.0094
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0026 0.0026 0.0471
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Plasmodium vivax thioredoxin reductase, putative 0.0126 0.0287 0.3687
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0079 0.0079
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0078 0.0162 0.0366
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0044 0.0073 0.0931
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0079 0.0179
Trichomonas vaginalis importin beta-1, putative 0.0041 0.0066 0.0257
Brugia malayi MH2 domain containing protein 0.0026 0.0026 0.0037
Loa Loa (eye worm) hypothetical protein 0.1713 0.4416 0.585
Trypanosoma brucei Heat shock protein 83, putative 0.0021 0.0013 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0077 0.0303
Trypanosoma cruzi Nicastrin, putative 0.0022 0.0017 0.0214
Plasmodium falciparum phd finger protein, putative 0.0029 0.0035 0.0453
Brugia malayi Dopamine receptor protein 1 0.0046 0.0079 0.0115
Echinococcus granulosus shaker cognate 0.0019 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0035
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0025 0.0024 0.0024
Leishmania major cytochrome p450-like protein 0.0031 0.004 0.0512
Loa Loa (eye worm) ion channel NompC 0.0019 0.001 0.0013
Onchocerca volvulus Cell death protein 3 homolog 0.0107 0.0236 0.0306
Echinococcus granulosus somatostatin receptor 0.0046 0.0079 0.0179
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0026 0.0026 0.0471
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0296 0.0729 0.0966
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0026 0.0026 0.0125
Trypanosoma brucei heat shock protein, putative 0.0021 0.0013 0.0161
Trichomonas vaginalis heat shock protein, putative 0.0016 0.0002 0.0007
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0057 0.0108 0.0129
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0025 0.0024 0.0093
Echinococcus granulosus fetal alzheimer antigen falz 0.0033 0.0045 0.0101
Schistosoma mansoni histone deacetylase 0.0268 0.0656 0.0782
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0059 0.007
Brugia malayi olfactory channel protein osm-9 0.0019 0.001 0.0014
Trypanosoma brucei importin beta-1 subunit, putative 0.0051 0.009 0.1162
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0079 0.0079
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0433 0.1086 0.4257
Schistosoma mansoni histone deacetylase 4 5 0.0314 0.0777 0.0925
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0015 0.0021
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0098 0.0215 0.0215
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.0124 0.0487
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0044 0.0073 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0026 0.0026 0.0031
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0046 0.0079 0.0079
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0026 0.0026 0.0059
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0074 0.0152 0.195
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0026 0.0026 0.0125
Loa Loa (eye worm) transcription factor SMAD2 0.0376 0.0938 0.1243
Schistosoma mansoni amine GPCR 0.0046 0.0079 0.0094
Echinococcus multilocularis thioredoxin glutathione reductase 0.0127 0.029 0.029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0223 0.054 0.0644
Trypanosoma cruzi ISWI complex protein 0.0022 0.0017 0.0217
Echinococcus granulosus heat shock protein 90 0.0021 0.0013 0.0029
Onchocerca volvulus Huntingtin homolog 0.027 0.0662 0.0871
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0026 0.0026 0.0126
Echinococcus granulosus metabotropic glutamate receptor 2 0.0042 0.0069 0.0156
Onchocerca volvulus 0.0126 0.0286 0.0372
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0117 0.0265 0.1377
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0019 0.001 0.001
Schistosoma mansoni histone deacetylase 0.0268 0.0656 0.0782
Schistosoma mansoni lipoxygenase 0.0054 0.0101 0.012
Onchocerca volvulus 0.0046 0.0079 0.0098
Echinococcus multilocularis short transient receptor potential channel 6 0.0019 0.001 0.001
Brugia malayi histone deacetylase 1 (HD1) 0.0268 0.0656 0.0952
Leishmania major hypothetical protein, conserved 0.0117 0.0265 0.3404
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0051 0.0051
Trypanosoma brucei heat shock protein 90, putative 0.0021 0.0013 0.0161
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0081 0.0169 0.1553
Echinococcus granulosus ryanodine receptor 44f 0.0019 0.001 0.0022
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0026 0.0026 0.0031
Trypanosoma brucei Nicastrin, putative 0.0022 0.0017 0.0214
Schistosoma mansoni hypothetical protein 0.0028 0.0031 0.0037
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.001 0.0022
Echinococcus multilocularis histone deacetylase 6 0.0314 0.0777 0.0777
Loa Loa (eye worm) hypothetical protein 0.0188 0.0448 0.0594
Schistosoma mansoni histone deacetylase hda2 0.0132 0.0303 0.0361
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.0124 0.0487
Schistosoma mansoni importin beta-1 0.0051 0.009 0.0108
Brugia malayi Tachykinin-like peptides receptor 99D 0.0046 0.0079 0.0115
Echinococcus granulosus intermediate filament protein 0.0018 0.0005 0.0012
Trypanosoma cruzi metacaspase, putative 0.0045 0.0077 0.0993
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0062 0.012 0.012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0073 0.0931
Brugia malayi Cytochrome P450 family protein 0.005 0.0088 0.0128
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0083 0.0175 0.0209
Giardia lamblia Grp94/Hsp90 0.0016 0.0002 0.0014
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0026 0.0026 0.0125
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0035 0.0049 0.0631
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0019 0.001 0.0121
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Schistosoma mansoni hypothetical protein 0.0102 0.0225 0.0268
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0026 0.0026 0.0125
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0019 0.001 0.001
Schistosoma mansoni amine GPCR 0.0046 0.0079 0.0094
Echinococcus multilocularis conserved hypothetical protein 0.0019 0.001 0.001
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.0079 0.0079
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0042 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.0026 0.0026 0.0031
Schistosoma mansoni hypothetical protein 0.006 0.0116 0.0139
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0286 0.034
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Brugia malayi ORL1-like opioid receptor 0.0046 0.0079 0.0115
Loa Loa (eye worm) hypothetical protein 0.0188 0.0447 0.0593
Echinococcus granulosus histone acetyltransferase MYST2 0.0042 0.0069 0.0157
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.001 0.001
Echinococcus granulosus presenilin 0.0124 0.0282 0.0638
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0131 0.0299 0.0676
Schistosoma mansoni caspase-7 (C14 family) 0.0098 0.0215 0.0256
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0126 0.0286 0.0286
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0046 0.0079 0.0079
Trypanosoma brucei histone deacetylase, putative 0.0314 0.0777 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0044 0.0073 0.0931
Trichomonas vaginalis Nicastrin precursor, putative 0.006 0.0116 0.0456
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0045
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0212 0.0509 1
Entamoeba histolytica hypothetical protein 0.0087 0.0185 0.1704
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0034 0.0132
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0024 0.0022 0.0207
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0268 0.0656 0.2574
Echinococcus multilocularis histone deacetylase 6 0.032 0.0793 0.0793
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.006 0.0115 0.0137
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.001 0.001
Echinococcus multilocularis expressed protein 0.0307 0.0757 0.0757
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0077 0.0303
Trypanosoma cruzi Aph-1 protein, putative 0.0115 0.0259 0.3332
Echinococcus granulosus caspase 3 0.0053 0.0096 0.0218
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0083 0.0175 0.2253
Onchocerca volvulus 0.0046 0.0079 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0026 0.0038
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.001 0.0011
Echinococcus multilocularis tumor protein p63 0.0329 0.0815 0.0815
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0147 0.0342 0.0342
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0046 0.0079 0.0105
Echinococcus granulosus 7TM GPCR rhodopsin 0.0046 0.0079 0.0179
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0038 0.0059 0.007
Echinococcus multilocularis caspase 3 0.0053 0.0096 0.0096
Schistosoma mansoni biogenic amine receptor 0.0046 0.0079 0.0094
Trypanosoma brucei cytochrome P450, putative 0.0031 0.004 0.0512
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0046 0.0079 0.0105
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0223 0.054 0.054
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0044 0.0073 0.0931
Onchocerca volvulus 0.0328 0.0812 0.107
Echinococcus multilocularis calcium activated potassium channel 0.002 0.0011 0.0011
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0026 0.0038
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0037 0.0056 0.0067
Toxoplasma gondii hypothetical protein 0.0035 0.005 0.0242
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0019 0.001 0.0014
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0024 0.0022 0.0088
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0026 0.0026 0.0031
Echinococcus multilocularis smad 0.0026 0.0026 0.0026
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0044 0.0073 0.0931
Echinococcus granulosus importin subunit beta 1 0.0051 0.009 0.0205
Mycobacterium ulcerans esterase/lipase LipP 0.0117 0.0265 0.5178
Echinococcus granulosus neuropeptide receptor 0.0046 0.0079 0.0179
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.0079 0.0105
Leishmania major hypothetical protein, conserved 0.0019 0.001 0.0121
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0035 0.017
Brugia malayi AKH receptor 0.0046 0.0079 0.0115
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0126 0.0286 0.138
Brugia malayi Presenilin-like protein At2g29900 0.0043 0.0072 0.0105
Brugia malayi Dopamine receptor protein 2 0.0046 0.0079 0.0115
Onchocerca volvulus 0.0046 0.0079 0.0098
Trichomonas vaginalis CMGC family protein kinase 0.0035 0.0049 0.0193
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.1713 0.4416 0.6406
Schistosoma mansoni hypothetical protein 0.0102 0.0225 0.0268
Brugia malayi Cyclic-nucleotide gated cation channel 0.0025 0.0024 0.0034
Brugia malayi G protein-coupled receptor 0.0046 0.0079 0.0115
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.1713 0.4416 1
Brugia malayi metabotropic glutamate receptor type 2 0.0025 0.0023 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0066 0.013 0.0155
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0323 0.0799 0.1059
Schistosoma mansoni methyl-cpg binding protein mbd 0.0025 0.0024 0.0028
Schistosoma mansoni histamine h1 receptor 0.0046 0.0079 0.0094
Schistosoma mansoni calcium-activated potassium channel 0.0019 0.001 0.0011
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0079 0.0079
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0026 0.0031
Brugia malayi cytochrome P450 0.0026 0.0026 0.0037
Schistosoma mansoni endoplasmin 0.0021 0.0013 0.0015
Trypanosoma cruzi metacaspase, putative 0.0045 0.0077 0.0993
Brugia malayi Melibiase family protein 0.006 0.0115 0.0167
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0074 0.0152 0.0343
Onchocerca volvulus 0.0061 0.0118 0.0149
Schistosoma mansoni zinc finger protein 0.0029 0.0033 0.004
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0026 0.0038
Brugia malayi hypothetical protein 0.006 0.0116 0.0169
Loa Loa (eye worm) hypothetical protein 0.0083 0.0175 0.0232
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.0079 0.0179
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0074 0.0152 0.0181
Plasmodium falciparum thioredoxin reductase 0.0126 0.0287 0.3687
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.009 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0103 0.0227 0.0301
Trypanosoma brucei Metacaspase-4 0.0045 0.0077 0.0993
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0024 0.0022 0.0286
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0077 0.0303
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0019 0.001 0.0121
Brugia malayi hypothetical protein 0.006 0.0116 0.0169
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0026 0.0026 0.0471
Echinococcus granulosus tar DNA binding protein 0.0066 0.013 0.0295
Loa Loa (eye worm) hypothetical protein 0.0037 0.0056 0.0074
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0046 0.0079 0.0115
Loa Loa (eye worm) DOMON domain-containing protein 0.0328 0.0812 0.1076
Brugia malayi Cytochrome P450 family protein 0.0031 0.004 0.0058
Trypanosoma cruzi trypanothione reductase, putative 0.0044 0.0073 0.0931
Onchocerca volvulus Phospholipase A2 homolog 0.2917 0.7548 1
Echinococcus multilocularis histone deacetylase 8 0.0132 0.0303 0.0303
Echinococcus multilocularis snurportin 1 0.0539 0.1362 0.1362
Brugia malayi Thioredoxin reductase 0.0126 0.0287 0.0416
Echinococcus granulosus voltage gated hydrogen channel 1 0.0019 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0029 0.0035 0.0047
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0026 0.0059
Brugia malayi gamma-secretase subunit pen-2 0.0116 0.0262 0.038
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0019 0.001 0.001
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0019 0.001 0.0014
Trichomonas vaginalis esterase, putative 0.0117 0.0265 0.1038
Echinococcus granulosus neuropeptide s receptor 0.0338 0.0838 0.1899
Schistosoma mansoni neuropeptide f receptor 76f 0.0046 0.0079 0.0094
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0046 0.0078 0.0113
Echinococcus granulosus apoptotic protease activating factor 1 0.0061 0.0118 0.0267
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0044 0.0073 0.035
Entamoeba histolytica histone deacetylase, putative 0.0268 0.0656 0.6046
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0026 0.0026 0.0471
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Trypanosoma cruzi heat shock protein 90, putative 0.0021 0.0013 0.0161
Onchocerca volvulus 0.0026 0.0026 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0049 0.0059
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0016 0.0002 0.0002
Toxoplasma gondii melibiase subfamily protein 0.009 0.0193 0.0931
Plasmodium vivax endoplasmin, putative 0.0021 0.0013 0.0161
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0026 0.0026 0.0026
Schistosoma mansoni ets-related 0.0172 0.0407 0.0485
Echinococcus multilocularis g-protein coupled receptor 0.0046 0.0079 0.0079
Echinococcus multilocularis histone deacetylase 3 0.0268 0.0656 0.0656
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Echinococcus granulosus g protein coupled receptor 0.0046 0.0079 0.0179
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0083 0.0175 0.0175
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0025 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.0079 0.0094
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0025 0.0024 0.0024
Echinococcus granulosus SAM and MBT domain containing protein 0.0037 0.0056 0.0126
Trypanosoma cruzi trypanothione reductase, putative 0.0126 0.0287 0.3687
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0083 0.0175 0.0397
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.009 0.0193 0.0437
Leishmania major hypothetical protein, unknown function 0.0019 0.001 0.0121
Echinococcus granulosus potassium large conductance calcium activated 0.0019 0.001 0.0022
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.002 0.0355
Trypanosoma brucei ISWI complex protein 0.0022 0.0017 0.0217
Brugia malayi neuropeptide F receptor 0.0046 0.0079 0.0115
Brugia malayi hypothetical protein 0.0043 0.0072 0.0105
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.001 0.0045
Schistosoma mansoni voltage-dependent calcium channel 0.0019 0.001 0.0011
Schistosoma mansoni heat shock protein 0.0021 0.0013 0.0015
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0044 0.0073 0.0931
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.009 0.0193 0.023
Schistosoma mansoni peptidylglycine monooxygenase 0.1713 0.4416 0.5259
Schistosoma mansoni adenoreceptor 0.0046 0.0079 0.0094
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0026 0.0026 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0026 0.0026 0.0038
Schistosoma mansoni voltage-gated ion channel 0.0019 0.001 0.0011
Echinococcus multilocularis sodium leak channel non selective protein 0.0019 0.001 0.001
Loa Loa (eye worm) histone deacetylase 1 0.0268 0.0656 0.087
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.0079 0.0179
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0079 0.0094
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0026 0.0026 0.0059
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0037 0.0056 0.0056
Schistosoma mansoni ran 0.0037 0.0056 0.0066
Echinococcus granulosus transient receptor potential gamma protein 0.0019 0.001 0.0022
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0046 0.0079 0.0105
Loa Loa (eye worm) hypothetical protein 0.0062 0.012 0.0159
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.002 0.0252
Onchocerca volvulus 0.0037 0.0056 0.0067
Schistosoma mansoni lipoxygenase 0.0078 0.0162 0.0192
Trypanosoma brucei heat shock protein, putative 0.0021 0.0013 0.0161
Schistosoma mansoni caspase-7 (C14 family) 0.0107 0.0236 0.0281
Trichomonas vaginalis histone deacetylase, putative 0.0268 0.0656 0.2574
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0046 0.0079 0.0115
Leishmania major GTP-binding protein, putative 0.0037 0.0056 0.0715
Trypanosoma cruzi metacaspase, putative 0.0045 0.0077 0.0993
Brugia malayi beta-lactamase family protein 0.0117 0.0265 0.0384
Brugia malayi DOMON domain containing protein 0.0328 0.0812 0.1178
Trichomonas vaginalis histone deacetylase, putative 0.0268 0.0656 0.2574
Echinococcus granulosus endoplasmin 0.0016 0.0002 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0026 0.0026 0.0125
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0044 0.0073 0.0931
Giardia lamblia Kinase, PLK 0.0063 0.0124 0.1141
Entamoeba histolytica hypothetical protein 0.0087 0.0185 0.1704
Echinococcus granulosus histone deacetylase 6 0.032 0.0793 0.1796
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.001 0.0045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0059 0.007
Trypanosoma cruzi Nicastrin, putative 0.0022 0.0017 0.0214
Echinococcus granulosus allatostatin A receptor 0.0046 0.0079 0.0179
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0059 0.054
Trypanosoma cruzi heat shock protein 85, putative 0.0021 0.0013 0.0161
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0035 0.0049 0.0631
Echinococcus multilocularis presenilin 0.0124 0.0282 0.0282
Schistosoma mansoni hypothetical protein 0.0226 0.0548 0.0652
Onchocerca volvulus 0.0046 0.0079 0.0098
Brugia malayi Importin beta-1 subunit 0.0051 0.009 0.0131
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Entamoeba histolytica Ran family GTPase 0.0037 0.0056 0.0514
Giardia lamblia Heat shock protein HSP 90-alpha 0.0016 0.0002 0.0014
Echinococcus multilocularis protein patched 0.0029 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0323 0.0799 0.1059
Toxoplasma gondii hypothetical protein 0.0019 0.001 0.0045
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0063 0.0124 0.0164
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.004 0.0064 0.0085
Echinococcus granulosus histone deacetylase 3 0.0268 0.0656 0.1487
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0026 0.0026 0.0125
Echinococcus multilocularis short transient receptor potential channel 6 0.0019 0.001 0.001
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0046 0.0079 0.0094
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.0124 0.0487
Schistosoma mansoni transient receptor potential channel 0.0019 0.001 0.0011
Schistosoma mansoni smad1 5 8 and 0.0026 0.0026 0.0031
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0025 0.0024 0.0031
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.0079 0.0105
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0073 0.0931
Schistosoma mansoni subfamily A22A unassigned peptidase (A22 family) 0.0124 0.0282 0.0336
Schistosoma mansoni hypothetical protein 0.0696 0.1769 0.2106
Onchocerca volvulus 0.0046 0.0079 0.0098
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0037 0.0056 0.0715
Toxoplasma gondii LsmAD domain-containing protein 0.0037 0.0054 0.0262
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0083 0.0175 0.2253
Loa Loa (eye worm) hypothetical protein 0.0037 0.0056 0.0074
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0044 0.0073 0.0931
Entamoeba histolytica hypothetical protein 0.0023 0.002 0.0182
Trypanosoma cruzi heat shock protein 85, putative 0.0021 0.0013 0.0161
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0073 0.0931
Trichomonas vaginalis mercuric reductase, putative 0.0044 0.0073 0.0284
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.013 0.0172
Onchocerca volvulus 0.0046 0.0079 0.0098
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0124 0.0282 0.3627
Plasmodium vivax histone deacetylase, putative 0.0132 0.0303 0.3904
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0102 0.0225 0.0509
Schistosoma mansoni endoplasmin 0.0021 0.0013 0.0015
Loa Loa (eye worm) TAR-binding protein 0.0066 0.013 0.0172
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0079 0.0094
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.001 0.001
Trichomonas vaginalis Nicastrin precursor, putative 0.006 0.0116 0.0456
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0025 0.0024 0.0054
Trypanosoma cruzi hypothetical protein, conserved 0.0117 0.0265 0.3404
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0026 0.0059
Schistosoma mansoni methyl-cpg binding protein mbd 0.0025 0.0024 0.0028
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0026 0.0031
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0045 0.0077 0.0373
Echinococcus granulosus expressed protein 0.0307 0.0757 0.1713
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0079 0.0094
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0019 0.001 0.0014
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0279 0.0685 0.1552
Brugia malayi Pre-SET motif family protein 0.0126 0.0286 0.0414
Brugia malayi Bromodomain containing protein 0.0033 0.0044 0.0064
Leishmania major histone deacetylase, putative 0.0314 0.0777 1
Onchocerca volvulus Bile acid receptor homolog 0.0026 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.006 0.0115 0.0152
Echinococcus multilocularis mitogen activated protein kinase 3 0.0035 0.0049 0.0049
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0046 0.0079 0.0098
Plasmodium falciparum histone deacetylase 1 0.0268 0.0656 0.8449
Schistosoma mansoni steroid hormone receptor ad4bp 0.0026 0.0026 0.0031
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0433 0.1086 1
Entamoeba histolytica presenilin 1 peptidase, putative 0.0124 0.0282 0.2596
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0026 0.0026 0.0125
Schistosoma mansoni hypothetical protein 0.0102 0.0225 0.0268
Loa Loa (eye worm) hypothetical protein 0.0061 0.0118 0.0156
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.001 0.0045
Onchocerca volvulus 0.0083 0.0175 0.0225
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0035 0.0049 0.0631
Toxoplasma gondii histone deacetylase HDAC1 0.0314 0.0777 0.3755
Mycobacterium ulcerans hypothetical protein 0.0117 0.0265 0.5178
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0026 0.0026 0.0471
Brugia malayi intermediate filament protein 0.0018 0.0005 0.0008
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0043 0.0072 0.0072
Echinococcus granulosus orexin receptor type 2 0.0046 0.0079 0.0179
Schistosoma mansoni tar DNA-binding protein 0.0066 0.013 0.0155
Brugia malayi MH2 domain containing protein 0.0026 0.0026 0.0037
Echinococcus multilocularis beta adrenergic receptor kinase 0.0016 0.0002 0.0002
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0016 0.0002 0.0004
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0044 0.0073 0.0371
Trypanosoma cruzi metacaspase, putative 0.0045 0.0077 0.0993
Schistosoma mansoni smad 0.0026 0.0026 0.0031
Echinococcus multilocularis caspase 2 0.0107 0.0236 0.0236
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0046 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0019 0.001 0.0011
Echinococcus granulosus neuropeptide receptor 0.0046 0.0079 0.0179
Echinococcus multilocularis hyperpolarization activated cyclic 0.0025 0.0024 0.0024
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0031 0.004 0.0753
Schistosoma mansoni neuropeptide receptor 0.0046 0.0079 0.0094
Schistosoma mansoni hypothetical protein 0.0221 0.0533 0.0635
Brugia malayi hypothetical protein 0.0046 0.0079 0.0115
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0117 0.0265 0.0351
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0077 0.0303
Loa Loa (eye worm) steroid hormone receptor 0.0026 0.0026 0.0035
Echinococcus multilocularis geminin 0.0696 0.1769 0.1769
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0026 0.0026 0.0471
Toxoplasma gondii histone deacetylase HDAC5 0.0132 0.0303 0.1466
Echinococcus multilocularis histone deacetylase 6 0.0314 0.0777 0.0777
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.001 0.0011
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0033 0.0045 0.0053
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0074 0.0152 0.2952
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0077 0.0303
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Schistosoma mansoni tar DNA-binding protein 0.0066 0.013 0.0155
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0019 0.001 0.0011
Schistosoma mansoni patched 1 0.0029 0.0034 0.004
Echinococcus multilocularis caspase 0.0098 0.0215 0.0215
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0079 0.0094
Echinococcus multilocularis survival motor neuron protein 1 0.0188 0.0447 0.0447
Brugia malayi beta-lactamase family protein 0.0117 0.0265 0.0384
Schistosoma mansoni tar DNA-binding protein 0.0066 0.013 0.0155
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Entamoeba histolytica hypothetical protein 0.0022 0.0017 0.0155
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0046 0.0079 0.0094
Echinococcus granulosus presenilin enhancer 2 0.0116 0.0262 0.0593
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.001 0.0011
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0046 0.0079 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0026 0.0026 0.0038
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0019 0.001 0.0022
Echinococcus granulosus GPCR family 2 0.0102 0.0225 0.0509
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.013 0.0189
Schistosoma mansoni voltage-gated potassium channel 0.0027 0.0029 0.0035
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0079 0.0079
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0019 0.001 0.0014
Schistosoma mansoni inositol monophosphatase 0.0024 0.0022 0.0027
Schistosoma mansoni sex comb on midleg homolog 0.0037 0.0056 0.0067
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0037 0.0056 0.0081
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0044 0.0073 0.0931
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.007 0.0159
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0131 0.0299 0.0299
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.002 0.0077
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0046 0.0079 0.0179
Trichomonas vaginalis heat shock protein, putative 0.0016 0.0002 0.0007
Echinococcus granulosus caspase 2 0.0107 0.0236 0.0535
Echinococcus granulosus nicalin 0.0022 0.0017 0.0038
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.1713 0.4416 0.6406
Plasmodium falciparum glutathione reductase 0.0126 0.0287 0.3687
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0077 0.0303
Brugia malayi PHD-finger family protein 0.0029 0.0035 0.0051
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0079 0.0079
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0038 0.0059 0.0282
Loa Loa (eye worm) MH2 domain-containing protein 0.0376 0.0938 0.1243
Plasmodium falciparum thioredoxin reductase 0.0044 0.0073 0.0931
Brugia malayi Serotonin receptor 0.0046 0.0079 0.0115
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.002 0.0252
Echinococcus multilocularis protein dispatched 1 0.0033 0.0044 0.0044
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0079 0.0094
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.001 0.0011
Leishmania major histone deacetylase, putative 0.0314 0.0777 1
Echinococcus multilocularis inositol monophosphatase 1 0.0024 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.015 0.035 0.0464
Trichomonas vaginalis histone deacetylase, putative 0.0268 0.0656 0.2574
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.004 0.0512
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0083 0.0175 0.1613
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0079 0.0079
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0083 0.0175 0.0397
Brugia malayi heat shock protein 90 0.0021 0.0013 0.0018
Plasmodium vivax metacaspase 1, putative 0.0045 0.0077 0.0993
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0019 0.001 0.0121
Echinococcus granulosus inositol monophosphatase 1 0.0024 0.0022 0.0051
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0121 0.0274 0.062
Loa Loa (eye worm) MBCTL1 0.0042 0.0069 0.0092
Trichomonas vaginalis D-aminoacylase, putative 0.0117 0.0265 0.1038
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0076 0.009
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0035
Brugia malayi MAP kinase sur-1 0.0035 0.0049 0.0071
Trypanosoma cruzi heat shock protein 85, putative 0.0016 0.0002 0.002
Toxoplasma gondii cytochrome p450 superfamily protein 0.0811 0.2069 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0046 0.0079 0.0094
Echinococcus granulosus heat shock protein 90 0.0016 0.0002 0.0004
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0043 0.0072 0.0104
Onchocerca volvulus Serine\/threonine kinase homolog 0.0063 0.0124 0.0157
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0026 0.0038
Plasmodium falciparum histone deacetylase, putative 0.0314 0.0777 1
Plasmodium vivax histone deacetylase, putative 0.0314 0.0777 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0044 0.0073 0.0073
Schistosoma mansoni peptidyl-glycine monooxygenase 0.1713 0.4416 0.5259
Mycobacterium leprae putative cytochrome p450 0.0026 0.0026 0.0304
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0026 0.0026 0.0125
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0433 0.1086 0.4257
Echinococcus multilocularis gamma secretase subunit aph 1 0.0296 0.0729 0.0729
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0083 0.0175 0.0687
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0025 0.0024 0.0028
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.001 0.001
Onchocerca volvulus Huntingtin homolog 0.027 0.0662 0.0871
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0046 0.0079 0.0094
Loa Loa (eye worm) thioredoxin reductase 0.0126 0.0287 0.038
Mycobacterium ulcerans beta-lactamase 0.0117 0.0265 0.5178
Trypanosoma cruzi metacaspase 5, putative 0.0045 0.0077 0.0993
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0026 0.0026 0.0038
Loa Loa (eye worm) hypothetical protein 0.0117 0.0265 0.0351
Brugia malayi cation channel family protein 0.0019 0.001 0.0014
Trichomonas vaginalis inositol monophosphatase, putative 0.0024 0.0022 0.0088
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0035
Brugia malayi hypothetical protein 0.0046 0.0079 0.0115
Schistosoma mansoni metabotropic glutamate receptor 0.0025 0.0023 0.0027
Loa Loa (eye worm) hypothetical protein 0.0182 0.0433 0.0573
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.001 0.0022
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0223 0.054 0.054
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.001 0.001
Echinococcus multilocularis apoptotic protease activating factor 1 0.0061 0.0118 0.0118
Brugia malayi cation channel family protein 0.0019 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0268 0.0656 0.087
Loa Loa (eye worm) gamma-secretase subunit pen-2 0.0116 0.0262 0.0347
Loa Loa (eye worm) hypothetical protein 0.0035 0.0051 0.0067
Schistosoma mansoni lamin 0.0018 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0026 0.0026 0.0471
Echinococcus multilocularis hyperpolarization activated cyclic 0.0025 0.0024 0.0024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0077 0.0303
Brugia malayi MH2 domain containing protein 0.0376 0.0938 0.1361
Schistosoma mansoni microtubule-associated protein tau 0.1022 0.2619 0.3119
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Echinococcus multilocularis somatostatin receptor 0.0046 0.0079 0.0079
Brugia malayi beta-lactamase 0.0117 0.0265 0.0384
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0035
Trichomonas vaginalis set domain proteins, putative 0.0996 0.2551 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0287 0.0706 0.3689
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0208 0.047
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0083 0.0175 0.2253
Mycobacterium ulcerans lipase LipD 0.0117 0.0265 0.5178
Brugia malayi Steroid receptor seven-up type 2 0.0026 0.0026 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0079 0.0094
Schistosoma mansoni RAR-like nuclear receptor 0.0026 0.0026 0.0031
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.001 0.001
Brugia malayi gamma-secretase subunit aph-1 0.0296 0.0729 0.1057
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0002 0.0002
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0083 0.0175 0.2253
Echinococcus granulosus neuropeptide receptor A26 0.0338 0.0838 0.1899
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0319 0.079 0.4125
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0013 0.005
Brugia malayi TAR-binding protein 0.0066 0.013 0.0189
Trichomonas vaginalis D-aminoacylase, putative 0.0117 0.0265 0.1038
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0025 0.0024 0.0054
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0025 0.0024 0.0054
Echinococcus multilocularis Glycoside hydrolase, family 27 0.009 0.0193 0.0193
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0126 0.0287 0.1491
Brugia malayi Fli-1 protein 0.0172 0.0407 0.0591
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0019 0.001 0.0014
Echinococcus granulosus sodium leak channel non selective protein 0.0019 0.001 0.0022
Echinococcus multilocularis voltage dependent calcium channel 0.0019 0.001 0.001
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0019 0.001 0.0022
Echinococcus multilocularis Niemann Pick C1 protein 0.0067 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Mycobacterium tuberculosis Probable lipase LipD 0.0117 0.0265 0.1377
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.001 0.0022
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0019 0.001 0.0121
Loa Loa (eye worm) melatonin receptor type 1A 0.0046 0.0079 0.0105
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Echinococcus multilocularis caspase 8 0.0045 0.0077 0.0077
Echinococcus multilocularis two pore calcium channel protein 2 0.0019 0.001 0.001
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0539 0.1362 0.1805
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0433 0.1086 0.4257
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0102 0.0225 0.0509
Loa Loa (eye worm) hypothetical protein 0.0056 0.0105 0.0139
Echinococcus granulosus thioredoxin glutathione reductase 0.0127 0.029 0.0656
Brugia malayi Bromodomain containing protein 0.0056 0.0104 0.0151
Echinococcus multilocularis lamin 0.0018 0.0005 0.0005
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0029 0.0038
Trypanosoma brucei histone deacetylase 1 0.0268 0.0656 0.8449
Leishmania major metacaspase, putative 0.0045 0.0077 0.0993
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0016 0.0002 0.002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0287 0.0706 0.3689
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0025 0.0024 0.0031
Loa Loa (eye worm) calcium channel 0.0019 0.001 0.0013
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0076 0.009
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0077 0.0303
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0038 0.0059 0.023
Brugia malayi G-protein coupled receptor 0.0046 0.0079 0.0115
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0026 0.0026
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0083 0.0175 0.0209
Loa Loa (eye worm) TYRA-2 protein 0.0046 0.0079 0.0105
Loa Loa (eye worm) hypothetical protein 0.0083 0.0175 0.0232
Leishmania major hypothetical protein, conserved 0.0035 0.005 0.0644
Trypanosoma brucei trypanothione reductase 0.0126 0.0287 0.3687
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0044 0.0073 0.0931
Echinococcus granulosus polycomb protein SCMH1 0.0037 0.0056 0.0126
Schistosoma mansoni biogenic amine receptor 0.0046 0.0079 0.0094
Loa Loa (eye worm) histone deacetylase 11 0.0132 0.0303 0.0402
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Schistosoma mansoni metabotropic glutamate receptor 0.0042 0.0069 0.0082
Brugia malayi Serotonin receptor 0.0046 0.0079 0.0115
Brugia malayi G-protein coupled receptor 0.0046 0.0079 0.0115
Trichomonas vaginalis chaperonin, putative 0.0016 0 0.0001
Loa Loa (eye worm) beta-lactamase 0.0117 0.0265 0.0351
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0026 0.0026 0.0035
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.0079 0.0079
Brugia malayi hypothetical protein 0.0087 0.0185 0.0268
Brugia malayi F/Y-rich N-terminus family protein 0.0017 0.0003 0.0005
Brugia malayi jmjC domain containing protein 0.0096 0.0209 0.0303
Trypanosoma cruzi importin beta-1 subunit, putative 0.0041 0.0066 0.0842
Schistosoma mansoni biogenic amine receptor 0.0046 0.0079 0.0094
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0044 0.0073 0.0931
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0026 0.0026 0.0038
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0041 0.0066 0.0257
Entamoeba histolytica heat shock protein 90, putative 0.0021 0.0013 0.0117
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0175 0.0396
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.0124 0.0487
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0287 0.0706 0.3689
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0019 0.001 0.0014
Toxoplasma gondii hypothetical protein 0.0019 0.001 0.0045
Mycobacterium tuberculosis Possible penicillin-binding protein 0.075 0.1912 1
Brugia malayi hypothetical protein 0.0188 0.0447 0.0649
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0083 0.0175 0.1612
Schistosoma mansoni hypothetical protein 0.0087 0.0185 0.022
Toxoplasma gondii HEAT repeat-containing protein 0.0051 0.009 0.0436
Echinococcus multilocularis musashi 0.0018 0.0005 0.0005
Echinococcus multilocularis beta LACTamase domain containing family member 0.0117 0.0265 0.0265
Echinococcus multilocularis transient receptor potential gamma protein 0.0019 0.001 0.001
Leishmania major cytochrome p450-like protein 0.0026 0.0026 0.0328
Brugia malayi Cytochrome P450 family protein 0.0026 0.0026 0.0037
Trypanosoma brucei Aph-1 protein, putative 0.0115 0.0259 0.3332
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0046 0.0079 0.0094
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0019 0.001 0.0014
Toxoplasma gondii hypothetical protein 0.0043 0.0072 0.0348
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0015 0.0033
Echinococcus multilocularis 0.0026 0.0026 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0026 0.0026 0.0125
Trypanosoma brucei metacaspase 0.0045 0.0077 0.0993
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0059 0.0078
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0026 0.0026 0.0125
Echinococcus granulosus g-protein coupled receptor 0.0046 0.0079 0.0179
Echinococcus multilocularis shaker cognate 0.0019 0.001 0.001
Trypanosoma brucei heat shock protein, putative 0.0021 0.0013 0.0161
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0035 0.017
Schistosoma mansoni retinoic acid receptor RXR 0.0026 0.0026 0.0031
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0044 0.0073 0.1394
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Leishmania major trypanothione reductase 0.0126 0.0287 0.3687
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0035 0.0049 0.0065
Brugia malayi Ets-domain containing protein 0.0057 0.0107 0.0155
Echinococcus multilocularis Smad4 0.0026 0.0026 0.0026
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0026 0.0026
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0033 0.0045 0.0045
Trypanosoma cruzi histone deacetylase 1, putative 0.0268 0.0656 0.8449
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0026 0.0026 0.0471
Loa Loa (eye worm) latrophilin receptor protein 2 0.0102 0.0225 0.0298
Schistosoma mansoni opsin-like receptor 0.0046 0.0079 0.0094
Schistosoma mansoni tar DNA-binding protein 0.0066 0.013 0.0155
Onchocerca volvulus 0.0046 0.0079 0.0098
Trypanosoma brucei polo-like protein kinase 0.0063 0.0124 0.1595
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Leishmania major importin beta-1 subunit, putative 0.0041 0.0066 0.0842
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.001 0.0045
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0016 0 0.0002
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0024 0.0022 0.0408
Onchocerca volvulus 0.0046 0.0079 0.0098
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0063 0.0124 0.1595
Brugia malayi MH1 domain containing protein 0.0026 0.0026 0.0037
Loa Loa (eye worm) voltage-gated calcium channel 0.0019 0.001 0.0013
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0027 0.0029 0.0029
Trypanosoma brucei hypothetical protein, conserved 0.0117 0.0265 0.3404
Schistosoma mansoni hypothetical protein 0.0539 0.1362 0.1622
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.001 0.0011
Onchocerca volvulus 0.0046 0.0079 0.0098
Schistosoma mansoni transient receptor potential channel 0.0019 0.001 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0079 0.0079
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0083 0.0175 0.0254
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0117 0.0155
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0026 0.0026 0.0471
Echinococcus granulosus ubiquitin specific protease 41 0.0083 0.0175 0.0397
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0223 0.054 0.0644
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0299 0.0356
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0019 0.001 0.0014
Brugia malayi Transient-receptor-potential like protein 0.0019 0.001 0.0014
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0024 0.0022 0.0286
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0015 0.0017
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0102 0.0225 0.0225
Schistosoma mansoni coup transcription factor 0.0026 0.0026 0.0031
Schistosoma mansoni ryanodine receptor related 0.0019 0.001 0.0011
Echinococcus multilocularis GA binding protein alpha chain 0.0057 0.0107 0.0107
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0073 0.0931
Brugia malayi glutathione reductase 0.0126 0.0287 0.0416
Schistosoma mansoni hypothetical protein 0.0046 0.0079 0.0094
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0026 0.0026 0.0125
Plasmodium falciparum heat shock protein 90 0.0021 0.0013 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0077 0.0303
Loa Loa (eye worm) voltage-gated potassium channel 0.0019 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0048 0.0084 0.0112
Plasmodium vivax importin-beta 2, putative 0.0051 0.009 0.1162
Brugia malayi hypothetical protein 0.0046 0.0079 0.0115
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0026 0.0026 0.0471
Echinococcus granulosus lamin dm0 0.0018 0.0005 0.0012
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0019 0.001 0.0022
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0045 0.0077 0.0112
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.0079 0.0079
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.001 0.0011
Brugia malayi RE15519p 0.0046 0.0079 0.0115
Echinococcus granulosus dro:myosuppressin receptor 0.0046 0.0079 0.0179
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0079 0.0179
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0268 0.0656 0.2574
Echinococcus multilocularis importin subunit beta 1 0.0051 0.009 0.009
Echinococcus granulosus sentrin specific protease 1 0.0038 0.0059 0.0133
Loa Loa (eye worm) hypothetical protein 0.0117 0.0265 0.0351
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0046 0.0079 0.0179
Loa Loa (eye worm) hypothetical protein 0.0117 0.0265 0.0351
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0024 0.0022 0.0286
Plasmodium vivax SET domain protein, putative 0.0126 0.0286 0.3675
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0035 0.0042
Plasmodium vivax heat shock protein 86, putative 0.0021 0.0013 0.0161
Loa Loa (eye worm) CYP4Cod1 0.0031 0.004 0.0053
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0024 0.0021 0.0268
Echinococcus granulosus histone lysine methyltransferase setb 0.015 0.035 0.0793
Echinococcus multilocularis G-protein coupled receptor, putative 0.0046 0.0079 0.0079
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.004 0.0512
Echinococcus granulosus serotonin receptor 0.0046 0.0079 0.0179
Brugia malayi N-terminal motif family protein 0.0117 0.0265 0.0384
Echinococcus granulosus gamma secretase subunit aph 1 0.0296 0.0729 0.1651
Schistosoma mansoni hypothetical protein 0.0028 0.0031 0.0037
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0212 0.0509 0.6444
Trypanosoma brucei histone deacetylase 3 0.0314 0.0777 1
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0015 0.0033
Echinococcus multilocularis voltage gated potassium channel 0.0027 0.0029 0.0029
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Brugia malayi Cytochrome P450 family protein 0.0031 0.004 0.0058
Echinococcus granulosus biogenic amine 5HT receptor 0.0046 0.0079 0.0179
Brugia malayi Bromodomain containing protein 0.0109 0.0243 0.0353
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0035 0.0049 0.0193
Trypanosoma cruzi histone deacetylase 1, putative 0.0268 0.0656 0.8449
Brugia malayi hypothetical protein 0.0046 0.0079 0.0115
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0044 0.0073 0.0931
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0844 0.2154 0.3125
Loa Loa (eye worm) hypothetical protein 0.0042 0.0069 0.0092
Plasmodium falciparum histone deacetylase 2 0.0314 0.0777 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.009 0.0193 0.023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0006
Onchocerca volvulus 0.0046 0.0079 0.0098
Trypanosoma brucei histone deacetylase 4 0.0314 0.0777 1
Plasmodium vivax hypothetical protein, conserved 0.0117 0.0265 0.3404
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0209 0.0473
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Trypanosoma cruzi polo-like protein kinase, putative 0.0063 0.0124 0.1595
Echinococcus granulosus methyl CpG binding domain protein 2 0.0025 0.0024 0.0054
Mycobacterium tuberculosis Probable lipase LipE 0.0117 0.0265 0.1377
Brugia malayi hypothetical protein 0.027 0.0662 0.0961
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0078
Onchocerca volvulus 0.0117 0.0265 0.0344
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.001 0.0022
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0087 0.0185 0.0185
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0026 0.0026 0.0471
Brugia malayi histone deacetylase 11 0.0132 0.0303 0.044
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0026 0.0026 0.0471
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0026 0.0328
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.0079 0.0079
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0019 0.001 0.0014
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0027 0.0029 0.0066
Echinococcus granulosus voltage gated potassium channel 0.0027 0.0029 0.0066
Schistosoma mansoni hypothetical protein 0.0028 0.0031 0.0037
Schistosoma mansoni voltage-gated cation channel 0.0019 0.001 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.0124 0.0487
Schistosoma mansoni hypothetical protein 0.0046 0.0079 0.0094
Echinococcus granulosus hypothetical protein 0.0019 0.001 0.0022
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0015 0.0015
Brugia malayi neuropeptide F receptor 0.0046 0.0079 0.0115
Loa Loa (eye worm) hypothetical protein 0.0221 0.0533 0.0706
Onchocerca volvulus 0.0048 0.0084 0.0105
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0087 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0048 0.0085 0.1636
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0223 0.054 0.0784
Trichomonas vaginalis CMGC family protein kinase 0.0035 0.0049 0.0193
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0046 0.0079 0.0115
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.006 0.0115 0.0137
Loa Loa (eye worm) endoplasmin 0.0021 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.2665 0.6893 0.9132
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0026 0.0034
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0042 0.0069 0.01
Mycobacterium tuberculosis Conserved protein 0.0117 0.0265 0.1377
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0175 0.0208
Echinococcus granulosus expressed conserved protein 0.0063 0.0122 0.0277
Brugia malayi voltage-dependent calcium channel 0.0019 0.001 0.0014
Schistosoma mansoni transient receptor potential channel 0.0019 0.001 0.0011
Giardia lamblia Histone deacetylase 0.0268 0.0656 0.6045
Loa Loa (eye worm) cytochrome P450 family protein 0.005 0.0088 0.0117
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0046 0.0079 0.0079
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0019 0.001 0.0022
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.001 0.0022
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0038 0.0059 0.007
Echinococcus multilocularis neuropeptide receptor 0.0046 0.0079 0.0079
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.0079 0.0105
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0026 0.0026 0.0059
Brugia malayi hypothetical protein 0.0046 0.0079 0.0115
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0077 0.0303
Brugia malayi hypothetical protein 0.0043 0.0072 0.0105
Echinococcus granulosus neuropeptide FF receptor 2 0.0046 0.0079 0.0179
Trypanosoma cruzi histone deacetylase, putative 0.0132 0.0303 0.3904
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0026 0.0026 0.0125
Toxoplasma gondii NADPH-glutathione reductase 0.0044 0.0073 0.035
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0045 0.0077 0.0373
Schistosoma mansoni myelin transcription factor 1 myt1 0.0042 0.0069 0.0082
Loa Loa (eye worm) hypothetical protein 0.0117 0.0265 0.0351
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.007 0.007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0079 0.0094
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0026 0.0026 0.0035
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0048 0.0085 0.0409
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.009 0.0193 0.023
Echinococcus multilocularis zinc finger protein 0.0029 0.0033 0.0033
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0026 0.0026 0.0471
Mycobacterium tuberculosis Conserved protein 0.0117 0.0265 0.1377
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0026 0.0038
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0037 0.0056 0.0512
Echinococcus granulosus Protein patched homolog 1 0.0029 0.0034 0.0076
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0044 0.0073 0.0931
Echinococcus granulosus G protein coupled receptor 139 0.0046 0.0079 0.0179
Echinococcus granulosus two pore calcium channel protein 2 0.0019 0.001 0.0022
Brugia malayi hypothetical protein 0.0046 0.0079 0.0115
Mycobacterium leprae conserved hypothetical protein 0.0117 0.0265 0.3337
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0079 0.0179
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0042 0.0069 0.0157
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.001 0.0011
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0299 0.5848
Schistosoma mansoni opsin-like receptor 0.0046 0.0079 0.0094
Schistosoma mansoni opsin-like receptor 0.0046 0.0079 0.0094
Schistosoma mansoni cytochrome P450 0.0026 0.0026 0.0031
Echinococcus multilocularis sentrin specific protease 1 0.0038 0.0059 0.0059
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0024 0.0022 0.2925
Trypanosoma cruzi PAB1-binding protein , putative 0.0037 0.0054 0.0699
Brugia malayi larval opioid receptor 0.0046 0.0079 0.0115
Brugia malayi Histone deacetylase 1 0.0268 0.0656 0.0952
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0081 0.0169 0.0662
Brugia malayi RNA, U transporter 1 0.0144 0.0333 0.0483
Echinococcus multilocularis fmrfamide receptor 0.0046 0.0079 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0079 0.0179
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0046 0.0079 0.0094
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0002 0.0002
Echinococcus granulosus histone deacetylase 8 0.0132 0.0303 0.0687
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0035 0.0035
Schistosoma mansoni gamma-secretase subunit aph-1 0.0296 0.0729 0.0868
Loa Loa (eye worm) hypothetical protein 0.0049 0.0085 0.0113
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Echinococcus multilocularis ubiquitin specific protease 41 0.0083 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Brugia malayi ecdysteroid receptor 0.0026 0.0026 0.0038
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Plasmodium falciparum metacaspase 1 0.0045 0.0077 0.0993
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0026 0.0026 0.0125
Brugia malayi Pre-SET motif family protein 0.0875 0.2236 0.3244
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0175 0.0254
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0016 0.0002 0.0002
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0074 0.0152 0.0152
Echinococcus multilocularis endoplasmin 0.0016 0.0002 0.0002
Echinococcus granulosus voltage dependent calcium channel 0.0019 0.001 0.0022
Loa Loa (eye worm) fli-1 protein 0.0172 0.0407 0.054
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Schistosoma mansoni inositol monophosphatase 0.0024 0.0022 0.0027
Loa Loa (eye worm) glutamate receptor 0.002 0.0011 0.0014
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.015 0.035 0.035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0079 0.0094
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0035 0.0049 0.0237
Brugia malayi Presenilin spe-4 0.0043 0.0072 0.0105
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.001 0.0022
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0037 0.0056 0.0269
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0079 0.0079
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0026 0.0026 0.0125
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0074 0.0152 0.1383
Onchocerca volvulus 0.0046 0.0079 0.0098
Schistosoma mansoni survival motor neuron protein 0.0038 0.0059 0.007
Loa Loa (eye worm) presenilin spe-4 0.0043 0.0072 0.0096
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0026 0.0026 0.0125
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0057 0.0107 0.0141
Echinococcus multilocularis Nicastrin 0.006 0.0116 0.0116
Echinococcus multilocularis heat shock protein 0.0021 0.0013 0.0013
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0077 0.0303
Loa Loa (eye worm) ryanodine receptor 0.0019 0.001 0.0013
Brugia malayi Dopamine receptor 0.0046 0.0079 0.0115
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.0079 0.0179
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0026 0.0026 0.0031
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0875 0.2236 0.2962
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0124 0.0148
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0147 0.0342 0.0773
Schistosoma mansoni smad1 5 8 and 0.0026 0.0026 0.0031
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0019 0.001 0.0014
Brugia malayi Presenilin family protein 0.0124 0.0282 0.0409
Trypanosoma cruzi ISWI complex protein 0.0022 0.0017 0.0217
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.0079 0.0079
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0029 0.0035 0.0042
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.002 0.0095
Echinococcus granulosus hyperpolarization activated cyclic 0.0025 0.0024 0.0054
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0043 0.0072 0.1382
Echinococcus granulosus tachykinin peptides receptor 99D 0.0046 0.0079 0.0179
Echinococcus granulosus histone deacetylase 1 0.0268 0.0656 0.1487
Brugia malayi photoreceptor-specific nuclear receptor 0.0026 0.0026 0.0038
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Brugia malayi DOMON domain containing protein 0.0328 0.0812 0.1178
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0279 0.0685 0.8822
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.0079 0.0105
Echinococcus multilocularis tar DNA binding protein 0.0066 0.013 0.013
Brugia malayi hypothetical protein 0.0024 0.0021 0.003
Brugia malayi hypothetical protein 0.0046 0.0079 0.0115
Echinococcus multilocularis mitogen activated protein kinase 0.0035 0.0049 0.0049
Toxoplasma gondii histone deacetylase HDAC2 0.0268 0.0656 0.3173
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0025 0.0024 0.0028
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.0079 0.0179
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Echinococcus granulosus zinc finger protein 0.0029 0.0033 0.0075
Brugia malayi Presenilin spe-4 0.0043 0.0072 0.0105
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Echinococcus granulosus lamin 0.0018 0.0005 0.0012
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0147 0.0341 0.0341
Schistosoma mansoni histone deacetylase 1 2 3 0.0132 0.0303 0.0361
Echinococcus granulosus hyperpolarization activated cyclic 0.0025 0.0024 0.0054
Mycobacterium tuberculosis Probable oxidoreductase 0.0319 0.079 0.4125
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0027 0.0029 0.0042
Loa Loa (eye worm) hypothetical protein 0.0117 0.0265 0.0351
Schistosoma mansoni kinase 0.021 0.0505 0.0601
Echinococcus granulosus g protein coupled receptor 0.0046 0.0079 0.0179
Brugia malayi sulfakinin receptor protein 0.0046 0.0079 0.0115
Echinococcus granulosus histone deacetylase 6 0.0314 0.0777 0.1759
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0068 0.0136 0.0162
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.009 0.0193 0.023
Echinococcus granulosus two pore calcium channel protein 1 0.0019 0.001 0.0022
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0035 0.0049 0.0631
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0077 0.0303
Loa Loa (eye worm) hypothetical protein 0.0102 0.0225 0.0298
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0035
Loa Loa (eye worm) glutamate receptor 0.005 0.009 0.0119
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.002 0.0077
Echinococcus multilocularis orexin receptor type 2 0.0046 0.0079 0.0079
Brugia malayi Smad1 0.0026 0.0026 0.0037
Trichomonas vaginalis histone deacetylase, putative 0.0268 0.0656 0.2574
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0052 0.0095 0.0095
Brugia malayi hypothetical protein 0.0061 0.0118 0.0171
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0024 0.0028
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0102 0.0225 0.0225
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.001 0.0011
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0026 0.0026 0.0471
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.002 0.2544
Loa Loa (eye worm) histone deacetylase 7A 0.0314 0.0777 0.1029
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0026 0.0034
Loa Loa (eye worm) hypothetical protein 0.0132 0.0303 0.0402
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Echinococcus multilocularis histone acetyltransferase MYST2 0.0042 0.0069 0.0069
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0043 0.0072 0.0086
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0019 0.001 0.001
Echinococcus granulosus histone deacetylase 6 0.0314 0.0777 0.1759
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.001 0.0011
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0154
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.012
Brugia malayi putative neuropeptide receptor NPR1 0.0046 0.0079 0.0115
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.0079 0.0094
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0032 0.0042 0.0062
Loa Loa (eye worm) histone deacetylase 0.0314 0.0777 0.1029
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.001 0.001
Echinococcus granulosus fmrfamide receptor 0.0046 0.0079 0.0179
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0079 0.0079
Trichomonas vaginalis D-aminoacylase, putative 0.0117 0.0265 0.1038
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0019 0.001 0.0011
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0024 0.0022 0.0286
Brugia malayi nuclear receptor NHR-88 0.0026 0.0026 0.0038
Toxoplasma gondii ABC1 family protein 0.0117 0.0265 0.1278
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0433 0.1086 1
Loa Loa (eye worm) mbt repeat family protein 0.0037 0.0056 0.0074
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0019 0.001 0.0014
Trichomonas vaginalis glutathione reductase, putative 0.0044 0.0073 0.0284
Onchocerca volvulus Histone deacetylase 10 homolog 0.0132 0.0303 0.0395
Echinococcus granulosus 7tm_1 domain containing protein 0.0046 0.0079 0.0179
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0287 0.0706 0.3689
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0037 0.0056 0.0074
Echinococcus multilocularis transfer RNA-Gly 0.0019 0.001 0.001
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0131 0.0299 0.1555
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.002 0.0166
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0044 0.0073 0.0164
Schistosoma mansoni amine GPCR 0.0046 0.0079 0.0094
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0026 0.0026 0.0471
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0026 0.0026 0.0059
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0124 0.0282 0.1105
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0038 0.0059 0.0085
Echinococcus granulosus sterol regulatory element binding protein 0.0029 0.0034 0.0076
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0026 0.0058
Onchocerca volvulus 0.0996 0.2551 0.3374
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0035 0.0049 0.0631
Schistosoma mansoni hypothetical protein 0.0046 0.0079 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0077 0.0303
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0433 0.1086 0.4257
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0077 0.0303
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.004 0.0053
Brugia malayi Melatonin receptor type 1A 0.0046 0.0079 0.0115
Echinococcus multilocularis presenilin enhancer 2 0.0116 0.0262 0.0262
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0079 0.0094
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0208 0.0208
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0117 0.0265 0.1377
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0026 0.0026 0.0328
Trypanosoma cruzi Aph-1 protein, putative 0.0115 0.0259 0.3332
Schistosoma mansoni vesicular amine transporter 0.0019 0.001 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0026 0.0026 0.0125
Trypanosoma cruzi metacaspase 5, putative 0.0045 0.0077 0.0993
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0117 0.0265 0.0344
Loa Loa (eye worm) RNA binding protein 0.0066 0.013 0.0172
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0026 0.0026
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0084 0.01
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Brugia malayi glucose-6-phosphate dehydrogenase 0.0074 0.0152 0.022
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0063 0.0124 0.0281
Toxoplasma gondii histone deacetylase HDAC3 0.0268 0.0656 0.3173
Loa Loa (eye worm) intermediate filament protein 0.0018 0.0005 0.0007
Echinococcus granulosus caspase 0.0098 0.0215 0.0486
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0046 0.0079 0.0079
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0035 0.0047
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0043 0.0072 0.1382
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0063 0.0124 0.0124
Onchocerca volvulus Protein ultraspiracle homolog 0.0026 0.0026 0.0027
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0037 0.0056 0.0715
Brugia malayi Intermediate filament tail domain containing protein 0.0018 0.0005 0.0008
Trichomonas vaginalis penicillin-binding protein, putative 0.0117 0.0265 0.1038
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0045 0.0077 0.0373
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0025 0.0023 0.0292
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0046 0.0079 0.0079
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0019 0.001 0.0006
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0016 0.0002 0.0003
Echinococcus multilocularis thyroid hormone receptor alpha 0.0026 0.0026 0.0026
Brugia malayi Presenilin spe-4 0.0043 0.0072 0.0105
Echinococcus multilocularis nicalin 0.0022 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Echinococcus granulosus heat shock protein 0.0021 0.0013 0.0029
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0015 0.0015
Toxoplasma gondii heat shock protein 90, putative 0.0021 0.0013 0.006
Echinococcus granulosus metabotropic glutamate receptor 5 0.0062 0.012 0.0273
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0433 0.1086 0.4257
Trichomonas vaginalis ran, putative 0.0037 0.0056 0.0219
Loa Loa (eye worm) histone deacetylase 3 0.0268 0.0656 0.087
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.001 0.0022
Echinococcus multilocularis SAM and MBT domain containing protein 0.0037 0.0056 0.0056
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.0079 0.0094
Loa Loa (eye worm) hypothetical protein 0.0045 0.0077 0.0102
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0046 0.0079 0.0105
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0299 0.5848
Mycobacterium leprae Probable lipase LipE 0.0117 0.0265 0.3337
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0035
Echinococcus granulosus GTP binding nuclear protein Ran 0.0037 0.0056 0.0126
Trypanosoma cruzi hypothetical protein, conserved 0.0117 0.0265 0.3404
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0029 0.0034 0.0045
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0079 0.0179
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0044 0.0073 0.1394
Trypanosoma cruzi histone deacetylase, putative 0.0314 0.0777 1
Giardia lamblia Heat shock protein HSP 90-alpha 0.0021 0.0013 0.0115
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0019 0.001 0.001
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0043 0.0072 0.0923
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0035 0.0453
Echinococcus granulosus smad 0.0026 0.0026 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0117 0.0265 0.0315
Schistosoma mansoni hypothetical protein 0.0019 0.001 0.0011
Trypanosoma brucei protein kinase, putative 0.0035 0.0049 0.0631
Onchocerca volvulus 0.0046 0.0079 0.0098
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.0079 0.0094
Mycobacterium tuberculosis Probable hydrolase 0.0117 0.0265 0.1377
Schistosoma mansoni Smad4 0.0026 0.0026 0.0031
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0026 0.0328
Trypanosoma brucei heat shock protein, putative 0.0021 0.0013 0.0161
Brugia malayi Metabotropic glutamate receptor precursor. 0.005 0.009 0.0131
Trypanosoma brucei heat shock protein, putative 0.0021 0.0013 0.0161
Echinococcus multilocularis neuropeptide FF receptor 2 0.0046 0.0079 0.0079
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0223 0.054 0.1224
Schistosoma mansoni hypothetical protein 0.0061 0.0118 0.014
Leishmania major heat shock protein 83-1 0.0021 0.0013 0.0161
Leishmania major hypothetical protein, conserved 0.0037 0.0054 0.0699
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0147 0.0341 0.0771
Trichomonas vaginalis CAMK family protein kinase 0.0063 0.0124 0.0487
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0124 0.0282 0.1105
Schistosoma mansoni bromodomain containing protein 0.0092 0.0199 0.0237
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0078 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0067 0.0133 0.0176
Loa Loa (eye worm) hypothetical protein 0.0037 0.0054 0.0072
Schistosoma mansoni hypothetical protein 0.0016 0.0002 0.0002
Loa Loa (eye worm) voltage-dependent calcium channel 0.0019 0.001 0.0013
Leishmania major histone deacetylase, putative 0.0268 0.0656 0.8449
Giardia lamblia Fructose-bisphosphate aldolase 0.0433 0.1086 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Echinococcus granulosus cytochrome P450 2K1 0.0026 0.0026 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Schistosoma mansoni hypothetical protein 0.0022 0.0017 0.002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0117 0.0265 0.0315
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0079 0.0179
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.001 0.0011
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0081 0.0169 0.0662
Onchocerca volvulus 0.0019 0.001 0.0006
Echinococcus granulosus tumor protein p63 0.0329 0.0815 0.1845
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0043 0.0072 0.0163
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0024 0.0022 0.0108
Schistosoma mansoni neuropeptide receptor 0.0046 0.0079 0.0094
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0026 0.0026 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0026 0.0026 0.0038
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0026 0.0026 0.0471
Echinococcus multilocularis neuropeptide receptor A26 0.0338 0.0838 0.0838
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0015 0.0018
Echinococcus multilocularis fmrfamide receptor 0.0046 0.0079 0.0079
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0158 0.0188
Brugia malayi ion channel NompC 0.0019 0.001 0.0014
Brugia malayi nuclear hormone receptor 0.0026 0.0026 0.0038
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0022 0.0016 0.0178
Onchocerca volvulus 0.0117 0.0265 0.0344
Echinococcus multilocularis Nicastrin 0.006 0.0116 0.0116
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.001 0.001
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0117 0.0265 0.5178
Loa Loa (eye worm) glutathione reductase 0.0126 0.0287 0.038
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0044 0.0073 0.0931
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0079 0.0079
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0038 0.0059 0.0085
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.001 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0026 0.0026 0.0038
Schistosoma mansoni intermediate filament proteins 0.0018 0.0005 0.0006
Echinococcus multilocularis histone deacetylase 7 0.0314 0.0777 0.0777
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0081 0.0169 0.217
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0019 0.001 0.0006
Echinococcus granulosus biogenic amine 5HT receptor 0.0046 0.0079 0.0179
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0083 0.0175 0.0175
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0081 0.0169 0.217
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0026 0.0026
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0087 0.0185 0.0419
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0079 0.0179
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0026 0.0026 0.0026
Entamoeba histolytica serine/threonine protein kinase, putative 0.0063 0.0124 0.1143
Echinococcus multilocularis histone deacetylase 1 0.0268 0.0656 0.0656
Echinococcus granulosus caspase 8 0.0045 0.0077 0.0175
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0037 0.0056 0.0715
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0105
Entamoeba histolytica hypothetical protein 0.0041 0.0066 0.0604
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0026 0.0026 0.0328
Giardia lamblia NADH oxidase lateral transfer candidate 0.0044 0.0073 0.0666
Leishmania major histone deacetylase, putative 0.0268 0.0656 0.8449
Schistosoma mansoni caspase-3 (C14 family) 0.0098 0.0215 0.0256
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0079 0.0079
Trypanosoma brucei histone deacetylase 2 0.0132 0.0303 0.3904
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0026 0.0038
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0026 0.0026 0.0471
Schistosoma mansoni hypothetical protein 0.0046 0.0079 0.0094
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0098 0.0215 0.0486
Schistosoma mansoni neuropeptide receptor 0.0046 0.0079 0.0094
Echinococcus multilocularis sodium channel protein 0.0279 0.0685 0.0685
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0074 0.0152 0.195
Schistosoma mansoni hypothetical protein 0.0038 0.0059 0.007
Echinococcus granulosus snurportin 1 0.0539 0.1362 0.3085
Leishmania major hypothetical protein, conserved 0.0022 0.0017 0.0217
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.006 0.0115 0.045
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.001 0.001
Echinococcus multilocularis sex peptide receptor 0.0046 0.0079 0.0079
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0223 0.054 0.1224
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0223 0.054 0.0716
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0046 0.0079 0.0079
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0019 0.001 0.0022
Schistosoma mansoni ran 0.0037 0.0056 0.0066
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0026 0.0038
Plasmodium vivax ataxin-2 like protein, putative 0.0037 0.0054 0.0699
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0019 0.001 0.0014
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0037 0.0056 0.0067
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0131 0.0299 0.3843
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0124 0.0282 0.3627

Activities

Activity type Activity value Assay description Source Reference
Activity (ADMET) 0 Toxicity against human RASF at 1 to 10 uM after 24 hrs ChEMBL. 17973469
Activity (functional) 0 Inhibition of IL1beta-induced sPLA2 production in human RASFs at 5 uM by ELISA ChEMBL. 17973469
Activity (functional) 0 Inhibition of IL1beta-induced MMP1 levels in human RASFs after 1 hr by ELISA ChEMBL. 17973469
Activity (functional) 0 Inhibition of IL1beta-induced MMP2 levels in human RASFs after 1 hr by ELISA ChEMBL. 17973469
Activity (functional) 0 Inhibition of IL1beta-induced MMP9 levels in human RASFs after 1 hr by ELISA ChEMBL. 17973469
Activity (functional) 0 Effect on IL1beta-stimulated TIMP2 production in human RASFs ChEMBL. 17973469
ED50 (functional) > 30 uM Inhibition Arachidonic acid(AA) induced contraction of GP lung tissue ChEMBL. 8978844
IC50 (binding) = 6.97 Inhibition of human sPLA2X using 1,2-bis(heptanoylthio) glycerophosphocholine substrate incubated for 30 mins ChEMBL. 25316315
IC50 (binding) = 50 nM Inhibition of human group2E phospholipase A2 fluorimetric assay ChEMBL. 18605714
IC50 (binding) = 60 nM Inhibition of human group2D phospholipase A2 by [3H]oleic acid-labeled Escherichia coli membrane assay ChEMBL. 18605714
IC50 (binding) = 70 nM Inhibition of mouse group2A phospholipase A2 fluorimetric assay ChEMBL. 18605714
IC50 (binding) = 75 nM Inhibition of mouse group2E phospholipase A2 fluorimetric assay ChEMBL. 18605714
IC50 (binding) = 75 nM Inhibition of human group2X phospholipase A2 fluorimetric assay ChEMBL. 18605714
IC50 (binding) = 75 nM Inhibition of mouse group2X phospholipase A2 fluorimetric assay ChEMBL. 18605714
IC50 (binding) = 125 nM Inhibition of human group2A phospholipase A2 fluorimetric assay ChEMBL. 18605714
IC50 (binding) = 130 nM Inhibition of human group2F phospholipase A2 fluorimetric assay ChEMBL. 18605714
IC50 (binding) = 140 nM Inhibition of mouse group1B phospholipase A2 fluorimetric assay ChEMBL. 18605714
IC50 (binding) = 430 nM Inhibition of mouse group2D phospholipase A2 fluorimetric assay ChEMBL. 18605714
IC50 (binding) = 500 nM Inhibition of human group2V phospholipase A2 fluorimetric assay ChEMBL. 18605714
IC50 (binding) = 750 nM Inhibition of human group1B phospholipase A2 fluorimetric assay ChEMBL. 18605714
IC50 (binding) = 750 nM Inhibition of mouse group2V phospholipase A2 fluorimetric assay ChEMBL. 18605714
IC50 (binding) > 1600 nM Inhibition of mouse group2F phospholipase A2 fluorimetric assay ChEMBL. 18605714
IC50 (binding) = 0.007 uM Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assay ChEMBL. 8978844
IC50 (binding) = 0.007 uM Inhibitory concentration against human nonpancreatic secretory phospholipase A2 ChEMBL. 15689175
IC50 (binding) = 0.007 uM Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assay ChEMBL. 8978844
IC50 (binding) = 0.007 uM Inhibitory concentration against human nonpancreatic secretory phospholipase A2 ChEMBL. 15689175
IC50 (binding) = 0.009 uM Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assay ChEMBL. 8978844
IC50 (binding) = 0.009 uM Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assay ChEMBL. 8978844
IC50 (binding) = 0.013 uM Inhibitory concentration against human nonpancreatic secretory phospholipase A2 ChEMBL. 15689175
IC50 (binding) = 0.013 uM Inhibitory concentration against human nonpancreatic secretory phospholipase A2 ChEMBL. 15689175
IC50 (binding) = 0.048 uM Compound was tested for inhibition of porcine secretory pancreatic PLA2 ChEMBL. 8978844
IC50 (binding) = 0.048 uM Compound was tested for inhibition of porcine secretory pancreatic PLA2 ChEMBL. 8978844
IC50 (binding) = 0.05 uM Inhibition of human recombinant sPLA2 G2E ChEMBL. 16686528
IC50 (binding) = 0.05 uM Inhibition of human recombinant sPLA2 G2E ChEMBL. 16686528
IC50 (binding) = 0.07 uM Inhibition of mouse recombinant sPLA2 G2A ChEMBL. 16686528
IC50 (binding) = 0.07 uM Inhibition of mouse recombinant sPLA2 G2A ChEMBL. 16686528
IC50 (binding) = 0.075 uM Inhibition of mouse recombinant sPLA2 G2E ChEMBL. 16686528
IC50 (binding) = 0.075 uM Inhibition of human recombinant sPLA2 G10 ChEMBL. 16686528
IC50 (binding) = 0.075 uM Inhibition of mouse recombinant sPLA2 G10 ChEMBL. 16686528
IC50 (binding) = 0.075 uM Inhibition of mouse recombinant sPLA2 G2E ChEMBL. 16686528
IC50 (binding) = 0.075 uM Inhibition of human recombinant sPLA2 G10 ChEMBL. 16686528
IC50 (binding) = 0.075 uM Inhibition of mouse recombinant sPLA2 G10 ChEMBL. 16686528
IC50 (binding) = 0.125 uM Inhibition of human recombinant sPLA2 G2A ChEMBL. 16686528
IC50 (binding) = 0.125 uM Inhibition of human recombinant sPLA2 G2A ChEMBL. 16686528
IC50 (binding) = 0.14 uM Inhibition of mouse recombinant sPLA2 G1B ChEMBL. 16686528
IC50 (binding) = 0.14 uM Inhibition of mouse recombinant sPLA2 G1B ChEMBL. 16686528
IC50 (binding) = 0.228 uM Compound was tested for inhibition of human secretory pancreatic Phospholipase A2 ChEMBL. 8978844
IC50 (binding) = 0.228 uM Compound was tested for inhibition of human secretory pancreatic Phospholipase A2 ChEMBL. 8978844
IC50 (binding) = 0.5 uM Inhibition of human recombinant sPLA2 G5 ChEMBL. 16686528
IC50 (binding) = 0.5 uM Inhibition of human recombinant sPLA2 G5 ChEMBL. 16686528
IC50 (binding) = 0.75 uM Inhibition of human recombinant sPLA2 G1B ChEMBL. 16686528
IC50 (binding) = 0.75 uM Inhibition of mouse recombinant sPLA2 G5 ChEMBL. 16686528
IC50 (binding) = 0.75 uM Inhibition of human recombinant sPLA2 G1B ChEMBL. 16686528
IC50 (binding) = 0.75 uM Inhibition of mouse recombinant sPLA2 G5 ChEMBL. 16686528
Inhibition (binding) < 50 % Inhibition of human group3 phospholipase-A2 at 1.6 uM ChEMBL. 18605714
Inhibition (binding) < 50 % Inhibition of human group12A phospholipase A2 at 1.6 uM ChEMBL. 18605714
KB (functional) = 0.083 uM Inhibition of Phospholipase A2 induced contraction of GP lung tissue ChEMBL. 8978844
Mole fraction (functional) = 0.0000018 Mole fraction is the IC50 concentration divided by the total lipid concentration (4000 microM) in DOC/PC assay ChEMBL. 8978844
Mole fraction (functional) = 0.0000073 Mole fraction of the IC50 concentration of compound divided by the total lipid concentration (1230 microM) in a chromogenic assay ChEMBL. 8978844

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

6 literature references were collected for this gene.

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