Detailed information for compound 1012666

Basic information

Technical information
  • TDR Targets ID: 1012666
  • Name: (7S,9S)-7-[(2S,4R,6S)-4-amino-6-methyloxan-2- yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)- 4-methoxy-8,10-dihydro-7H-tetracene-5,12-dion e
  • MW: 527.52 | Formula: C27H29NO10
  • H donors: 5 H acceptors: 7 LogP: 2.19 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](N)C[C@@H](O2)C)c2c(C1)c(O)c1c(c2O)C(=O)c2c(C1=O)cccc2OC
  • InChi: 1S/C27H29NO10/c1-11-6-12(28)7-18(37-11)38-16-9-27(35,17(30)10-29)8-14-20(16)26(34)22-21(24(14)32)23(31)13-4-3-5-15(36-2)19(13)25(22)33/h3-5,11-12,16,18,29,32,34-35H,6-10,28H2,1-2H3/t11-,12+,16-,18-,27-/m0/s1
  • InChiKey: ITSGNOIFAJAQHJ-BMFNZSJVSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (7S,9S)-7-[(2S,4R,6S)-4-amino-6-methyl-tetrahydropyran-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
  • (7S,9S)-7-[[(2S,4R,6S)-4-amino-6-methyl-2-tetrahydropyranyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
  • (7S,9S)-7-[(2S,4R,6S)-4-amino-6-methyl-tetrahydropyran-2-yl]oxy-9-glycoloyl-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-quinone
  • (7S,9S)-7-[(2S,4R,6S)-4-amino-6-methyl-oxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyethanoyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0022 0.0028
Onchocerca volvulus 0.0307 0.1147 0.7976
Schistosoma mansoni apoferritin-2 0.0018 0.0017 0.0031
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0106 0.0106
Echinococcus multilocularis synaptojanin 1 0.0019 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0022 0.0168
Trypanosoma brucei glucose transporter 2A 0.0307 0.1147 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0096 0.0322 0.338
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0014
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0028 0.0055 0.0457
Mycobacterium tuberculosis Probable exported protein 0.0019 0.002 0.0027
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0055 0.0457
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0157 0.0196
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0099 0.084
Loa Loa (eye worm) oxidoreductase 0.0014 0.0003 0.0014
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0307 0.1147 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Loa Loa (eye worm) hypothetical protein 0.0043 0.0116 0.0496
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0014 0.0017
Loa Loa (eye worm) MBCTL1 0.0055 0.0164 0.07
Onchocerca volvulus 0.0019 0.0022 0.0131
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0019 0.002 0.018
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0247 0.2132
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0019 0.0137
Loa Loa (eye worm) hypothetical protein 0.0316 0.1182 0.5057
Schistosoma mansoni sugar transporter 0.0307 0.1147 0.2161
Loa Loa (eye worm) cytochrome P450 0.0035 0.0085 0.0363
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0106 0.0106
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0022 0.0042
Schistosoma mansoni polycystin 1-related 0.0019 0.0022 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0019 0.0137
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0085 0.0085
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0035 0.0085 0.0713
Loa Loa (eye worm) hypothetical protein 0.01 0.0338 0.1447
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0009 0.0009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0106 0.0734
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0008 0.001
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0078 0.0524
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0099 0.0865
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0282 0.1051 0.1307
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0003 0.0022
Echinococcus multilocularis snurportin 1 0.0611 0.2337 0.2337
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.015 0.0532 0.0837
Schistosoma mansoni smad 0.0017 0.0014 0.0026
Loa Loa (eye worm) hypothetical protein 0.0152 0.0542 0.2319
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0019 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Brugia malayi MH1 domain containing protein 0.0017 0.0014 0.0095
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0216 0.1863
Toxoplasma gondii exonuclease III APE 0.0092 0.0307 0.266
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0028 0.0055 0.0457
Brugia malayi hypothetical protein 0.0307 0.1147 0.798
Giardia lamblia Sugar-proton symporter 0.0307 0.1147 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0028 0.0055 0.0344
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0237 0.0875 0.3745
Loa Loa (eye worm) hypothetical protein 0.0381 0.1437 0.6149
Toxoplasma gondii sugar transporter ST1 0.0307 0.1147 1
Schistosoma mansoni nuclear hormone receptor 0.004 0.0106 0.0199
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0019 0.0023
Trypanosoma cruzi cytochrome P450, putative 0.0052 0.0153 0.1308
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0106 0.0713
Echinococcus granulosus sodium:myo inositol cotransporter 0.0076 0.0245 0.0304
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0307 0.1147 1
Brugia malayi steroid hormone receptor 0.004 0.0106 0.0734
Giardia lamblia Kinase, PLK 0.0096 0.0322 0.2713
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0035 0.0085 0.0713
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Loa Loa (eye worm) acetyltransferase 0.0146 0.052 0.2223
Brugia malayi Sugar transporter family protein 0.0307 0.1147 0.798
Toxoplasma gondii transporter, cation channel family protein 0.0043 0.0116 0.0986
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0022 0.0027
Loa Loa (eye worm) hypothetical protein 0.004 0.0106 0.0451
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0164 0.0164
Echinococcus multilocularis geminin 0.137 0.5308 0.5308
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0085 0.0741
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.002 0.0148
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.002 0.0148
Schistosoma mansoni hypothetical protein 0.137 0.5308 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0092 0.0307 0.1315
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.0593 0.4111
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0014
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0035 0.0085 0.0713
Echinococcus granulosus mitogen activated protein kinase 3 0.011 0.0376 0.0468
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0062 0.0265
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.0322 0.2786
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0085 0.0741
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Brugia malayi TAR-binding protein 0.0062 0.0191 0.1332
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0022 0.0022
Echinococcus multilocularis pyruvate kinase 0.0033 0.0078 0.0078
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0019 0.002 0.0148
Brugia malayi hypothetical protein 0.0307 0.1147 0.798
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Brugia malayi hypothetical protein 0.0019 0.0022 0.0153
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0035 0.0085 0.0713
Brugia malayi Major Facilitator Superfamily protein 0.0307 0.1147 0.798
Echinococcus granulosus cpg binding protein 0.0061 0.0187 0.0232
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0022 0.0022
Leishmania major pantothenate kinase subunit, putative 0.0021 0.0028 0.0216
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0022 0.0027
Schistosoma mansoni hypothetical protein 0.0611 0.2337 0.4403
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.002 0.0148
Echinococcus multilocularis pyruvate kinase 0.0033 0.0078 0.0078
Trichomonas vaginalis ran, putative 0.0042 0.0112 0.0979
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0035 0.0085 0.0713
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0031 0.0133
Schistosoma mansoni apoferritin-2 0.0018 0.0017 0.0031
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0019 0.0166
Giardia lamblia Inositol 5-phosphatase 4 0.0019 0.002 0.0049
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0152 0.1305
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0035 0.0085 0.0713
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0099 0.084
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.01 0.0338 0.042
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0106 0.0734
Plasmodium vivax hypothetical protein, conserved 0.0255 0.0945 0.8238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0051 0.1176
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0106 0.0131
Trypanosoma brucei THT1 - hexose transporter, putative 0.0307 0.1147 1
Brugia malayi exodeoxyribonuclease III family protein 0.0092 0.0307 0.2139
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0035 0.0085 0.0129
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0106 0.0451
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0099 0.0186
Brugia malayi RNA, U transporter 1 0.0163 0.0584 0.4064
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Echinococcus granulosus pyruvate kinase 0.0017 0.0015 0.0018
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0019 0.002 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0152 0.1305
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0099 0.084
Giardia lamblia PHD finger protein 15 0.0029 0.0062 0.0417
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0018 0.0017 0.0141
Leishmania major endonuclease/exonuclease protein-like protein 0.0019 0.002 0.0148
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0182 0.0658 0.1036
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0307 0.1147 0.1147
Echinococcus granulosus pyruvate kinase 0.0017 0.0015 0.0018
Brugia malayi Importin beta-1 subunit 0.0057 0.0171 0.1192
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0028 0.0055 0.0083
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0022 0.0094
Schistosoma mansoni transcription factor LCR-F1 0.0255 0.0946 0.1782
Brugia malayi hypothetical protein 0.0019 0.0021 0.0145
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0112 0.014
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0032 0.025
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0567 0.3945
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0009 0.0055
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0019 0.002 0.0148
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0099 0.084
Trypanosoma brucei glucose transporter, putative 0.0307 0.1147 1
Leishmania major hypothetical protein, conserved 0.0307 0.1147 1
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0307 0.1147 1
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0019 0.0137
Trypanosoma brucei glucose transporter, putative 0.0307 0.1147 1
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.002 0.0086
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0099 0.0099
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0019 0.002 0.0176
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0035 0.0085 0.0713
Echinococcus multilocularis microtubule associated protein 2 0.0668 0.2559 0.2559
Echinococcus granulosus traf and tnf receptor associated protein 0.0019 0.002 0.0025
Trypanosoma brucei glucose transporter, putative 0.0307 0.1147 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0089
Mycobacterium tuberculosis Probable reductase 0.0182 0.0658 0.1036
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0031 0.0039
Echinococcus multilocularis segment polarity protein dishevelled 0.0019 0.0021 0.0021
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0307 0.1147 0.1147
Echinococcus granulosus solute carrier family 5 0.0076 0.0245 0.0304
Leishmania major glucose transporter, lmgt2 0.0307 0.1147 1
Mycobacterium tuberculosis Probable lipase LipE 0.0255 0.0945 0.1491
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0154 0.0552 0.0686
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0031 0.0216
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0078 0.0545
Echinococcus granulosus neuropeptide s receptor 0.047 0.1787 0.2222
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0112 0.048
Trypanosoma brucei unspecified product 0.0027 0.0052 0.0428
Schistosoma mansoni sugar transporter 0.0307 0.1147 0.2161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Loa Loa (eye worm) sugar transporter 0.0307 0.1147 0.4907
Leishmania major glucose transporter, lmgt3 0.0307 0.1147 1
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0003 0.0022
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0021 0.0039
Schistosoma mansoni sugar transporter 0.0307 0.1147 0.2161
Loa Loa (eye worm) beta-lactamase 0.0255 0.0945 0.4045
Loa Loa (eye worm) hypothetical protein 0.0038 0.0096 0.0409
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0282 0.1051 0.1051
Toxoplasma gondii facilitative glucose transporter GT1 0.0307 0.1147 1
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0099 0.084
Leishmania major pyruvate kinase 0.0033 0.0078 0.0657
Entamoeba histolytica hypothetical protein 0.0255 0.0946 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0065 0.0544
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.052 0.052
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0062 0.0117
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Loa Loa (eye worm) hypothetical protein 0.0039 0.0099 0.0425
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0046 0.037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0094
Schistosoma mansoni cpg binding protein 0.0061 0.0187 0.0352
Mycobacterium tuberculosis Conserved protein 0.0255 0.0945 0.1491
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0035 0.0085 0.0129
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0314 0.1174 0.2212
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0112 0.0954
Brugia malayi Carboxylesterase family protein 0.0069 0.0217 0.1508
Brugia malayi ecdysone receptor 0.0019 0.0022 0.0153
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0021 0.0026
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0106 0.0199
Trichomonas vaginalis myo-inositol transporter, putative 0.0307 0.1147 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.008 0.0259 0.0405
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0133
Schistosoma mansoni rab6-interacting 0.0019 0.0022 0.0042
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0164 0.0203
Entamoeba histolytica hypothetical protein 0.0255 0.0946 1
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0931 0.8116
Onchocerca volvulus 0.0307 0.1147 0.7976
Schistosoma mansoni hypothetical protein 0.0019 0.0022 0.0042
Echinococcus granulosus sodium:glucose cotransporter 2 0.0076 0.0245 0.0304
Echinococcus granulosus Pleckstrin G protein interacting region 0.0019 0.0021 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0307 0.1147 1
Leishmania major hypothetical protein, conserved 0.0019 0.002 0.0148
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0076 0.0245 0.211
Brugia malayi Cytochrome P450 family protein 0.0052 0.0153 0.1063
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.002 0.0148
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0039 0.0049
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0019 0.002 0.018
Mycobacterium leprae conserved hypothetical protein 0.0255 0.0945 1
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0593 0.5168
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0028 0.0055 0.0457
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0019 0.0081
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.002 0.0148
Echinococcus granulosus Solute carrier family 22 5 0.2069 0.8042 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0019 0.0137
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0099 0.069
Schistosoma mansoni hypothetical protein 0.01 0.0338 0.0637
Brugia malayi serine/threonine-protein kinase plk-2 0.0096 0.0322 0.2239
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0106 0.0734
Toxoplasma gondii hypothetical protein 0.0038 0.0096 0.0809
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0247 0.2132
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0022 0.0028
Brugia malayi hypothetical protein 0.0139 0.049 0.3408
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0129 0.11
Echinococcus granulosus voltage dependent calcium channel 0.0043 0.0116 0.0144
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0094
Chlamydia trachomatis pyruvate kinase 0.0033 0.0078 0.1194
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0022 0.0042
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.01 0.0338 0.2353
Echinococcus granulosus segment polarity protein dishevelled 0.0019 0.0021 0.0026
Toxoplasma gondii sugar transporter ST3 0.0307 0.1147 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0144 0.1493
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0062 0.0077
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0144 0.0144
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0078 0.0657
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0019 0.002 0.018
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0014 0.0017
Echinococcus granulosus solute carrier family 22 0.0307 0.1147 0.1426
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0307 0.1147 0.1426
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0171 0.147
Plasmodium vivax SET domain protein, putative 0.003 0.0065 0.0544
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0322 0.2806
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0129 0.1125
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0376 0.3279
Echinococcus granulosus mitogen activated protein kinase 0.011 0.0376 0.0468
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0931 0.8116
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.002 0.014
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0102 0.1045
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0106 0.0734
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0184 0.0785
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0015 0.01
Brugia malayi RNA binding protein 0.0062 0.0191 0.1332
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0019 0.0137
Schistosoma mansoni hypothetical protein 0.0029 0.0062 0.0117
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.0171 0.147
Trypanosoma brucei RNA editing exonuclease 2 0.0019 0.002 0.0148
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0099 0.084
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0099 0.084
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0019 0.0137
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0039 0.0377
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0035 0.0085 0.0713
Brugia malayi latrophilin 2 splice variant baaae 0.0216 0.0791 0.5506
Loa Loa (eye worm) hypothetical protein 0.0069 0.0217 0.0927
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0191 0.1332
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0035 0.0085 0.0129
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0089
Echinococcus granulosus segment polarity protein dishevelled 0.0019 0.0021 0.0026
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0035 0.0085 0.0713
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0028 0.0055 0.0069
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.002 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0307 0.1147 1
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0078 0.0119
Plasmodium falciparum glutathione reductase 0.0028 0.0055 0.0457
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0051 0.0416
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0106 0.0713
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0567 0.2426
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0137 0.0588
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0247 0.0247
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0028 0.0055 0.0457
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0085 0.0715
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0019 0.0019
Brugia malayi MH2 domain containing protein 0.0017 0.0014 0.0095
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0255 0.0945 0.4045
Echinococcus granulosus carboxylesterase 5A 0.0069 0.0217 0.027
Echinococcus multilocularis thioredoxin glutathione reductase 0.0081 0.0263 0.0263
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0099 0.0187
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0019 0.0166
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0051 0.0504
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0322 0.04
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0066
Echinococcus multilocularis pyruvate kinase 0.0026 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0133
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0099 0.0099
Trypanosoma cruzi mitochondrial protein 99, putative 0.0019 0.002 0.0148
Echinococcus granulosus snurportin 1 0.0611 0.2337 0.2907
Toxoplasma gondii ABC1 family protein 0.0255 0.0945 0.8238
Echinococcus multilocularis acetylcholinesterase 0.0069 0.0217 0.0217
Onchocerca volvulus 0.003 0.0065 0.0434
Schistosoma mansoni nocturnin 0.0019 0.002 0.0038
Loa Loa (eye worm) hypothetical protein 0.0255 0.0945 0.4045
Mycobacterium tuberculosis Possible penicillin-binding protein 0.163 0.6323 1
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0112 0.0862
Echinococcus multilocularis deoxyribonuclease 1 2 0.0019 0.002 0.002
Brugia malayi GH02984p 0.0076 0.0245 0.1702
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0129 0.1125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0112 0.0954
Schistosoma mansoni ferritin 0.0018 0.0017 0.0031
Plasmodium falciparum phd finger protein, putative 0.0029 0.0062 0.0513
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0065 0.0123
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0009 0.0009
Plasmodium vivax hexose transporter 0.0307 0.1147 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0504 0.0626
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0052 0.0428
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.002 0.0086
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0092 0.0307 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0085 0.0741
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0191 0.0361
Loa Loa (eye worm) hypothetical protein 0.0029 0.0062 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0307 0.1147 1
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0593 0.5168
Brugia malayi Sugar transporter family protein 0.0307 0.1147 0.798
Mycobacterium tuberculosis Probable esterase LipL 0.0255 0.0945 0.1491
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0036 0.0088 0.011
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.01 0.0338 0.042
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0019 0.0137
Treponema pallidum NADH oxidase 0.0028 0.0055 0.1338
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0106 0.0734
Trypanosoma brucei trypanothione reductase 0.008 0.0259 0.2236
Brugia malayi MH1 domain containing protein 0.0017 0.0014 0.0095
Trichomonas vaginalis D-aminoacylase, putative 0.0255 0.0945 0.8243
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0035 0.0085 0.0713
Loa Loa (eye worm) hypothetical protein 0.004 0.0106 0.0451
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0021 0.0021
Schistosoma mansoni cript-related 0.0019 0.002 0.0038
Giardia lamblia DINP protein human, muc B family 0.0039 0.0099 0.0747
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0316 0.1182 0.5057
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0078 0.0524
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0003 0.0022
Onchocerca volvulus 0.0092 0.0306 0.211
Toxoplasma gondii sugar transporter ST2 0.0307 0.1147 1
Trichomonas vaginalis ap endonuclease, putative 0.0092 0.0307 0.268
Loa Loa (eye worm) hypothetical protein 0.0055 0.0164 0.07
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.002 0.014
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0055 0.0457
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0106 0.0451
Leishmania major RNA-editing complex protein MP100, putative 0.0019 0.002 0.0148
Loa Loa (eye worm) hypothetical protein 0.0255 0.0945 0.4045
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Loa Loa (eye worm) hypothetical protein 0.0076 0.0245 0.1046
Trypanosoma brucei unspecified product 0.0039 0.0099 0.084
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0099 0.084
Echinococcus multilocularis synaptic vesicle 2 protein 0.0307 0.1147 0.1147
Echinococcus multilocularis traf and tnf receptor associated protein 0.0019 0.002 0.002
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0376 0.3279
Schistosoma mansoni ran 0.0042 0.0112 0.0212
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0022 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Echinococcus multilocularis muscleblind protein 0.0152 0.0542 0.0542
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0106 0.0734
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0086
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0051 0.0416
Loa Loa (eye worm) DIX domain-containing protein 0.0019 0.0021 0.0089
Loa Loa (eye worm) hypothetical protein 0.0069 0.0217 0.0927
Schistosoma mansoni lipoxygenase 0.0054 0.0157 0.0296
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0035 0.0085 0.0713
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Brugia malayi Thioredoxin reductase 0.008 0.0259 0.1802
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0056 0.007
Echinococcus granulosus RUN 0.0019 0.0022 0.0028
Loa Loa (eye worm) hypothetical protein 0.0057 0.0171 0.0733
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0028 0.0055 0.0457
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0003 0.0022
Brugia malayi tailless protein 0.0019 0.0022 0.0153
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0022 0.0027
Loa Loa (eye worm) major facilitator superfamily transporter 0.0307 0.1147 0.4907
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0112 0.0781
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0019 0.0081
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0008 0.001
Brugia malayi hypothetical protein 0.0034 0.008 0.0555
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0191 0.0819
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0019 0.0137
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0144 0.0223
Schistosoma mansoni microtubule-associated protein tau 0.0668 0.2559 0.4821
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0151 0.054 0.4694
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0085 0.0106
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.011 0.0376 0.326
Brugia malayi beta-lactamase 0.0255 0.0945 0.6578
Echinococcus granulosus long chain fatty acid transport protein 4 0.0151 0.054 0.0672
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0022 0.0022
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0055 0.0457
Trypanosoma brucei cytochrome P450, putative 0.0052 0.0153 0.1308
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0019 0.0131
Echinococcus multilocularis smad 0.0017 0.0014 0.0014
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0003 0.0022
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0307 0.1147 0.1426
Onchocerca volvulus 0.0307 0.1147 0.7976
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0322 0.0322
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0085 0.0591
Echinococcus granulosus FTZ F1 alpha 0.004 0.0106 0.0131
Brugia malayi nuclear receptor NHR-88 0.004 0.0106 0.0734
Brugia malayi jmjC domain containing protein 0.0096 0.0322 0.224
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0046 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0174 0.0744
Echinococcus granulosus endonuclease exonuclease phosphatase 0.021 0.0768 0.0955
Loa Loa (eye worm) CYP4Cod1 0.0052 0.0153 0.0654
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0031 0.0058
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0022 0.0022
Plasmodium falciparum hexose transporter 0.0307 0.1147 1
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0019 0.002 0.018
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0022 0.0027
Mycobacterium leprae putative cytochrome p450 0.0035 0.0085 0.0866
Schistosoma mansoni dishevelled 0.0019 0.0021 0.0039
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0035 0.0085 0.0129
Schistosoma mansoni hypothetical protein 0.0035 0.0085 0.016
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0106 0.0734
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0112 0.0954
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0099 0.084
Brugia malayi AMP-binding enzyme family protein 0.0164 0.0588 0.4092
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0322 0.2806
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0116 0.0144
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0094
Schistosoma mansoni pyruvate kinase 0.0033 0.0078 0.0148
Toxoplasma gondii hypothetical protein 0.0019 0.0021 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0322 0.2806
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0154 0.0552 0.1039
Mycobacterium tuberculosis Probable dehydrogenase 0.0182 0.0658 0.1036
Brugia malayi Cytochrome P450 family protein 0.0052 0.0153 0.1063
Schistosoma mansoni ferritin light chain 0.0018 0.0017 0.0031
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0019 0.002 0.0148
Entamoeba histolytica Ran family GTPase 0.0042 0.0112 0.1157
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0003 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0322 0.2806
Loa Loa (eye worm) hypothetical protein 0.004 0.0106 0.0451
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Mycobacterium tuberculosis Probable hydrolase 0.0255 0.0945 0.1491
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0154 0.0552 0.0552
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0164 0.0308
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0307 0.1147 0.1147
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.002 0.0027 0.0187
Echinococcus granulosus synaptojanin 1 0.0019 0.002 0.0025
Mycobacterium ulcerans hypothetical protein 0.0255 0.0945 0.8238
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0022 0.0022
Loa Loa (eye worm) DR-78 0.0019 0.0022 0.0094
Mycobacterium ulcerans bacterioferritin BfrA 0.0018 0.0017 0.0117
Echinococcus granulosus dna polymerase eta 0.0039 0.0099 0.0123
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0092 0.0307 0.0481
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0154 0.0552 0.3839
Trichomonas vaginalis penicillin-binding protein, putative 0.0255 0.0945 0.8243
Onchocerca volvulus 0.0307 0.1147 0.7976
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0247 0.0307
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0092 0.0307 0.266
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0153 0.0654
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0019 0.0137
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0035 0.0085 0.0713
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0085 0.0741
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0106 0.0199
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0028 0.0055 0.0457
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0035 0.0085 0.0713
Schistosoma mansoni alpha-glucosidase 0.0136 0.0481 0.0906
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0028 0.0055 0.0457
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0028 0.0055 0.0457
Echinococcus multilocularis mitogen activated protein kinase 3 0.011 0.0376 0.0376
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0202 0.0737 0.7792
Trypanosoma brucei glucose transporter, putative 0.0307 0.1147 1
Trichomonas vaginalis glutathione reductase, putative 0.0028 0.0055 0.0483
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0094
Trichomonas vaginalis D-aminoacylase, putative 0.0255 0.0945 0.8243
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0008 0.0008
Plasmodium vivax glutathione reductase, putative 0.008 0.0259 0.2236
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.0567 0.0705
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0089
Schistosoma mansoni hypothetical protein 0.0307 0.1147 0.2161
Trypanosoma brucei glucose transporter, putative 0.0307 0.1147 1
Schistosoma mansoni rab6-interacting 0.0019 0.0022 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0102 0.0769
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0046 0.0057
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0247 0.7927
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0035 0.0085 0.0129
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0022 0.0042
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0255 0.0945 0.6578
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0046 0.0397
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0157 0.0157
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0009 0.0009
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0106 0.0734
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0567 0.0567
Echinococcus multilocularis Smad4 0.0017 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0086
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0028 0.0055 0.0457
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.011 0.0376 0.326
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0074 0.0236 0.2039
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0085 0.0741
Leishmania major trypanothione reductase 0.008 0.0259 0.2236
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0191 0.0191
Onchocerca volvulus 0.0307 0.1147 0.7976
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0076 0.0245 0.0245
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0092 0.0307 0.2585
Echinococcus granulosus solute carrier family 22 0.0307 0.1147 0.1426
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0307 0.1147 0.1147
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0035 0.0085 0.0129
Plasmodium falciparum thioredoxin reductase 0.0028 0.0055 0.0457
Echinococcus multilocularis expressed protein 0.0018 0.0017 0.0017
Schistosoma mansoni ferritin 0.0018 0.0017 0.0031
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0019 0.002 0.0148
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0022 0.0042
Schistosoma mansoni hypothetical protein 0.01 0.0338 0.0637
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0247 0.2589
Plasmodium vivax sugar transporter, putative 0.0307 0.1147 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0307 0.1147 0.1426
Leishmania major DNA polymerase kappa, putative 0.0039 0.0099 0.084
Echinococcus granulosus beta LACTamase domain containing family member 0.0255 0.0945 0.1176
Loa Loa (eye worm) calcium channel 0.0154 0.0552 0.236
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0282 0.1051 0.1051
Trichomonas vaginalis penicillin-binding protein, putative 0.0255 0.0945 0.8243
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0018 0.0017 0.0021
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0019 0.002 0.0148
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0085 0.0867
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.002 0.0148
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0247 0.0466
Loa Loa (eye worm) hypothetical protein 0.0139 0.049 0.2096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Loa Loa (eye worm) carboxylesterase 0.0069 0.0217 0.0927
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0078 0.0683
Mycobacterium ulcerans sugar transporter 0.0307 0.1147 1
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.002 0.014
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0255 0.0945 0.1781
Brugia malayi Probable ClpP-like protease 0.0077 0.0247 0.1719
Schistosoma mansoni nuclear receptor 0.0019 0.0022 0.0042
Loa Loa (eye worm) hypothetical protein 0.0033 0.0078 0.0335
Brugia malayi jmjC domain containing protein 0.0039 0.0099 0.0688
Loa Loa (eye worm) hypothetical protein 0.005 0.0144 0.0614
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0154 0.0552 0.0552
Trypanosoma brucei glucose transporter, putative 0.0307 0.1147 1
Leishmania major glucose transporter, lmgt1 0.0307 0.1147 1
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0099 0.084
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0106 0.0734
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0035 0.0085 0.0713
Schistosoma mansoni nuclear receptor 0.0019 0.0022 0.0042
Trichomonas vaginalis ap endonuclease, putative 0.0092 0.0307 0.268
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0009 0.0055
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0065 0.0123
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Schistosoma mansoni hypothetical protein 0.0023 0.0039 0.0074
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0022 0.0022
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0076 0.0245 0.0245
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0015 0.01
Brugia malayi Sodium:solute symporter family protein 0.0076 0.0245 0.1702
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0164 0.0588 0.2516
Trichomonas vaginalis Phospholipase C precursor, putative 0.0019 0.002 0.0176
Leishmania major GTP-binding protein, putative 0.0042 0.0112 0.0954
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0019 0.002 0.0148
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Echinococcus granulosus dna polymerase kappa 0.0039 0.0099 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0307 0.1147 1
Mycobacterium ulcerans beta-lactamase 0.0255 0.0945 0.8238
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0245 0.0462
Trichomonas vaginalis sugar transport protein, putative 0.0307 0.1147 1
Loa Loa (eye worm) hypothetical protein 0.0255 0.0945 0.4045
Entamoeba histolytica hypothetical protein 0.0255 0.0946 1
Loa Loa (eye worm) sugar transporter 0.0307 0.1147 0.4907
Mycobacterium tuberculosis Conserved protein 0.0255 0.0945 0.1491
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0152 0.1305
Trypanosoma cruzi hexose transporter, putative 0.0307 0.1147 1
Trichomonas vaginalis glucose transporter, putative 0.0307 0.1147 1
Giardia lamblia Pyruvate kinase 0.0033 0.0078 0.0562
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0094
Schistosoma mansoni Smad4 0.0017 0.0014 0.0026
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0019 0.0036
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.01 0.0338 0.0338
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0021 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0099 0.084
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.002 0.0086
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0021 0.0145
Giardia lamblia Kinase, CMGC MAPK 0.011 0.0376 0.3192
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0247 0.204
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0096 0.0322 0.2786
Loa Loa (eye worm) glutathione reductase 0.008 0.0259 0.1108
Echinococcus multilocularis sodium channel protein 0.0036 0.0088 0.0088
Loa Loa (eye worm) thioredoxin reductase 0.008 0.0259 0.1108
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0022 0.0153
Schistosoma mansoni loxhd1 0.0019 0.0022 0.0042
Mycobacterium ulcerans bacterioferritin BfrB 0.0018 0.0017 0.0117
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.002 0.0027 0.0187
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0003 0.0006
Schistosoma mansoni kinase 0.0049 0.014 0.0263
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0099 0.084
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0096 0.0322 0.1377
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0094
Echinococcus granulosus microtubule associated protein 2 0.0668 0.2559 0.3182
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0094
Toxoplasma gondii transporter, major facilitator family protein 0.0307 0.1147 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0182 0.0658 0.695
Schistosoma mansoni lipoxygenase 0.0019 0.0022 0.0042
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0019 0.002 0.0148
Brugia malayi beta-lactamase family protein 0.0255 0.0945 0.6578
Trypanosoma cruzi hexose transporter 0.0307 0.1147 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0248 0.0918 0.3926
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0009 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0085 0.0741
Brugia malayi hypothetical protein 0.0021 0.0031 0.0216
Brugia malayi Major Facilitator Superfamily protein 0.0307 0.1147 0.798
Trypanosoma brucei THT1 - hexose transporter, putative 0.0307 0.1147 1
Schistosoma mansoni hypothetical protein 0.137 0.5308 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0282 0.1051 0.1981
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0019 0.002 0.0176
Echinococcus multilocularis pyruvate kinase 0.0017 0.0015 0.0015
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0085 0.0713
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0022 0.0131
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0247 0.2132
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0191 0.0361
Onchocerca volvulus Serine\/threonine kinase homolog 0.0096 0.0322 0.2222
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0058 0.0405
Trypanosoma brucei polo-like protein kinase 0.0096 0.0322 0.2786
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0137 0.0171
Echinococcus multilocularis dna polymerase eta 0.0039 0.0099 0.0099
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0164 0.0588 0.5113
Echinococcus multilocularis long chain fatty acid transport protein 4 0.0151 0.054 0.054
Leishmania major hypothetical protein, conserved 0.0255 0.0945 0.8238
Brugia malayi CCR4 0.0019 0.002 0.014
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0136
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0152 0.1305
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0076 0.0245 0.0304
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0014 0.0058
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0085 0.0741
Brugia malayi Sugar transporter family protein 0.0307 0.1147 0.798
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0106 0.0451
Onchocerca volvulus 0.0307 0.1147 0.7976
Brugia malayi major facilitator superfamily protein 0.0307 0.1147 0.798
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0003 0.0004
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.002 0.0148
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0099 0.0865
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.0432 0.0814
Loa Loa (eye worm) hypothetical protein 0.003 0.0065 0.028
Onchocerca volvulus 0.0049 0.0137 0.0935
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0106 0.0451
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Echinococcus granulosus sodium:glucose cotransporter 0.0076 0.0245 0.0304
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0593 0.5168
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0085 0.0715
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0099 0.0423
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0035 0.0085 0.0129
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0191 0.0819
Brugia malayi CXXC zinc finger family protein 0.0058 0.0174 0.1211
Mycobacterium leprae Probable lipase LipE 0.0255 0.0945 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0567 0.0567
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0019 0.002 0.0086
Echinococcus multilocularis cpg binding protein 0.0061 0.0187 0.0187
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0046 0.037
Schistosoma mansoni hypothetical protein 0.0825 0.3173 0.5978
Loa Loa (eye worm) hypothetical protein 0.004 0.0106 0.0451
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0137 0.0935
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0133
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0014 0.0014
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0009 0.001
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.021 0.0768 0.0768
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0076 0.0245 0.0245
Schistosoma mansoni alpha glucosidase 0.0035 0.0085 0.016
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0086
Schistosoma mansoni carbon catabolite repressor protein 0.0019 0.002 0.0038
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0019 0.0137
Giardia lamblia NADH oxidase lateral transfer candidate 0.0028 0.0055 0.036
Toxoplasma gondii hypothetical protein 0.0026 0.0051 0.0416
Schistosoma mansoni neutral sphingomyelinase 0.0019 0.002 0.0038
Schistosoma mansoni high-affinity choline transporter 0.0076 0.0245 0.0461
Echinococcus granulosus voltage dependent calcium channel 0.0154 0.0552 0.0686
Echinococcus granulosus ferritin 0.0018 0.0017 0.0021
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0085 0.0713
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0096
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0137 0.0259
Brugia malayi beta-lactamase family protein 0.0255 0.0945 0.6578
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0085 0.0364
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0019 0.002 0.0176
Toxoplasma gondii thioredoxin reductase 0.008 0.0259 0.2236
Echinococcus multilocularis ferritin 0.0018 0.0017 0.0017
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0009 0.0055
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0022 0.0131
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0009 0.0066
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0282 0.1051 0.4498
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0376 0.326
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0307 0.1147 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0255 0.0945 0.8238
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.002 0.0148
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.0395 0.3424
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0099 0.084
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0099 0.084
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0099 0.0123
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0019 0.0137
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0092 0.0307 0.266
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.002 0.0148
Loa Loa (eye worm) hypothetical protein 0.004 0.0106 0.0451
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0065 0.0065
Echinococcus multilocularis RUN 0.0019 0.0022 0.0022
Brugia malayi follicle stimulating hormone receptor 0.0237 0.0875 0.6089
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0116 0.0984
Onchocerca volvulus 0.023 0.0849 0.5897
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0003 0.0022
Onchocerca volvulus 0.0076 0.0245 0.1683
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0116 0.1009
Leishmania major importin beta-1 subunit, putative 0.0046 0.0129 0.11
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0069 0.0216 0.0216
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0019 0.002 0.0176
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0106 0.0713
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0035 0.0085 0.0129
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0191 0.0361
Echinococcus multilocularis solute carrier family 5 0.0076 0.0245 0.0245
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.0217 0.0408
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0106 0.0131
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0137 0.0171
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0022 0.0153
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0062 0.0513
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0019 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0593 0.5168
Brugia malayi conserved hypotetical protein 0.0019 0.0022 0.0153
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0096
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0022 0.0094
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0099 0.0152
Schistosoma mansoni smad1 5 8 and 0.0017 0.0014 0.0026
Leishmania major pyruvate kinase 0.0033 0.0078 0.0657
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0009 0.0055
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0152 0.1305
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.052 0.3615
Loa Loa (eye worm) hypothetical protein 0.0076 0.0245 0.1046
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.011 0.0376 0.326
Brugia malayi nuclear receptor NHR-67 0.0019 0.0022 0.0153
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0202 0.0737 0.1162
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0092 0.0307 0.0307
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0307 0.1147 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0316 0.1182 0.8224
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0008 0.0008
Brugia malayi isocitrate dehydrogenase 0.0016 0.0009 0.0066
Brugia malayi nuclear hormone receptor 0.004 0.0106 0.0734
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0092 0.0307 0.266
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0078 0.0335
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0154 0.0552 0.1039
Brugia malayi mbt repeat family protein 0.0049 0.0137 0.0955
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0099 0.0123
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0096 0.0322 0.0322
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0022 0.0096
Loa Loa (eye worm) hypothetical protein 0.0023 0.0039 0.0166
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0094
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0019 0.002 0.0176
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0247 0.2132
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0046 0.0086
Brugia malayi hypothetical protein 0.0255 0.0946 0.6581
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0022 0.0042
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0035 0.0085 0.0713
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0133
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0216 0.0408
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0046 0.0317
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Echinococcus granulosus acetylcholinesterase 0.0069 0.0217 0.027
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Echinococcus multilocularis carboxylesterase 5A 0.0069 0.0217 0.0217
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0106 0.0734
Loa Loa (eye worm) hypothetical protein 0.0139 0.049 0.2096
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0164 0.0164
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0092 0.0307 0.266
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0003 0.0014
Echinococcus granulosus pyruvate kinase 0.0017 0.0015 0.0018
Trypanosoma cruzi mitochondrial protein 99, putative 0.0019 0.002 0.0148
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.002 0.0148
Leishmania major hypothetical protein, conserved 0.0019 0.002 0.0148
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0065 0.0123
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0099 0.084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0035 0.0085 0.0129
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0035 0.0085 0.0713
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0216 0.1863
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0099 0.0186
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0019 0.002 0.0148
Schistosoma mansoni coup transcription factor 0.004 0.0106 0.0199
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0069 0.0216 0.0337
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0009 0.0055
Schistosoma mansoni ap endonuclease 0.0092 0.0307 0.0579
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.011 0.0376 0.326
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0003 0.0028
Echinococcus granulosus Smad4 0.0017 0.0014 0.0017
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0247 0.2132
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0069 0.0216 0.0269
Mycobacterium ulcerans lipase LipD 0.0255 0.0945 0.8238
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0078 0.0657
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0022 0.0027
Echinococcus granulosus geminin 0.137 0.5308 0.6601
Trichomonas vaginalis conserved hypothetical protein 0.0307 0.1147 1
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0046 0.037
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0116 0.1009
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0593 0.5168
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0031 0.0216
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0106 0.0131
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0191 0.0361
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0019 0.002 0.0148
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0255 0.0946 0.0946
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0116 0.0984
Onchocerca volvulus 0.004 0.0106 0.0713
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0019 0.002 0.0148
Trypanosoma brucei glucose transporter 1E 0.0307 0.1147 1
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0015 0.01
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0021 0.0028 0.0216
Echinococcus multilocularis solute carrier family 22 0.0307 0.1147 0.1147
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0099 0.084
Trichomonas vaginalis ferritin, putative 0.0018 0.0017 0.0144
Plasmodium falciparum DNase I-like protein, putative 0.0019 0.002 0.0148
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0255 0.0945 0.1781
Onchocerca volvulus 0.0019 0.002 0.0118
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0031 0.0058
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0019 0.002 0.018
Onchocerca volvulus Huntingtin homolog 0.0139 0.049 0.3394
Onchocerca volvulus 0.0307 0.1147 0.7976
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0009 0.0055
Leishmania major DNA polymerase eta, putative 0.0039 0.0099 0.084
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.002 0.014
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0019 0.002 0.018
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0092 0.0307 0.2573
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0021 0.0021
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0106 0.0199
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0182 0.0658 0.1036
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0062 0.0513
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Loa Loa (eye worm) hypothetical protein 0.0255 0.0945 0.4045
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0307 0.1147 0.2161
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0099 0.0425
Schistosoma mansoni FFA transport protein 0.0151 0.054 0.1018
Brugia malayi Muscleblind-like protein 0.0152 0.0542 0.3771
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0251 0.0931 0.6477
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0381 0.1437 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0085 0.0741
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0019 0.002 0.002
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0078 0.0683
Schistosoma mansoni glucose transport protein 0.0307 0.1147 0.2161
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0164 0.0203
Schistosoma mansoni thyroid hormone receptor 0.004 0.0106 0.0199
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Loa Loa (eye worm) hypothetical protein 0.0216 0.0791 0.3386
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0022 0.0153
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0035 0.0085 0.0129
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0255 0.0946 0.1176
Mycobacterium tuberculosis Probable oxidoreductase 0.0202 0.0737 0.1162
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0094
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0376 0.0709
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Leishmania major myo-inositol/proton symporter (MIT) 0.0307 0.1147 1
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.002 0.014
Plasmodium falciparum glutathione reductase 0.008 0.0259 0.2236
Plasmodium vivax hypothetical protein, conserved 0.0019 0.002 0.0148
Brugia malayi Doublecortin family protein 0.0019 0.0022 0.0156
Echinococcus multilocularis 0.0035 0.0085 0.0085
Echinococcus multilocularis dnaJ subfamily B 0.0825 0.3173 0.3173
Trypanosoma brucei glucose transporter, putative 0.0307 0.1147 1
Echinococcus granulosus solute carrier family 22 0.0307 0.1147 0.1426
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0035 0.0085 0.0129
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0152 0.1305
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0019 0.0021 0.0021
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0019 0.002 0.018
Trypanosoma brucei glucosidase, putative 0.0035 0.0085 0.0715
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0628 0.5471
Trypanosoma brucei sugar transporter, putative 0.0307 0.1147 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0009 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0106 0.0131
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0045 0.0085
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Plasmodium vivax thioredoxin reductase, putative 0.008 0.0259 0.2236
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0022 0.0022
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0216 0.1863
Echinococcus multilocularis solute carrier family 22 0.0307 0.1147 0.1147
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0021 0.0026
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0018 0.0017 0.0021
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0009 0.0055
Giardia lamblia GTOR 0.0018 0.0019 0.0037
Leishmania major cytochrome p450-like protein 0.0035 0.0085 0.0713
Trypanosoma brucei hypothetical protein, conserved 0.0255 0.0945 0.8238
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0133
Echinococcus granulosus dnaJ subfamily B 0.0825 0.3173 0.3946
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0106 0.0106
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0593 0.5168
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0112 0.0954
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0019 0.0036
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0085 0.0867
Brugia malayi Bromodomain containing protein 0.0033 0.0076 0.0528
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0019 0.0137
Mycobacterium tuberculosis Conserved protein 0.0255 0.0945 0.1491
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0055 0.0457
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0009 0.0055
Onchocerca volvulus Putative neutral sphingomyelinase 0.0019 0.002 0.0118
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.002 0.0148
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0102 0.0861
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0028 0.0055 0.0457
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0078 0.0657
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0035 0.0085 0.0129
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0019 0.002 0.018
Brugia malayi MH2 domain containing protein 0.0248 0.0918 0.6385
Trypanosoma brucei unspecified product 0.0027 0.0052 0.0428
Loa Loa (eye worm) hypothetical protein 0.0255 0.0945 0.4045
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0019 0.0021 0.0123
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0316 0.1182 0.8224
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0376 0.326
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0099 0.084
Brugia malayi MAP kinase sur-1 0.011 0.0376 0.2617
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Brugia malayi hypothetical protein 0.0021 0.0031 0.0216
Echinococcus multilocularis pyruvate kinase 0.0017 0.0015 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0035 0.0085 0.0129
Echinococcus multilocularis importin subunit beta 1 0.0057 0.0171 0.0171
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0039 0.0166
Echinococcus multilocularis solute carrier family 22 0.0307 0.1147 0.1147
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0019 0.0137
Schistosoma mansoni glucose transporter 0.0307 0.1147 0.2161
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0035 0.0085 0.0713
Trypanosoma cruzi sugar transporter, putative 0.0307 0.1147 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0065 0.0065
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0019 0.0138
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0171 0.147
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0106 0.0131
Trypanosoma brucei protein kinase, putative 0.011 0.0376 0.326
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0094
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0376 0.3279
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0028 0.0055 0.0457
Brugia malayi PHD-finger family protein 0.0029 0.0062 0.043
Brugia malayi Cytochrome P450 family protein 0.0035 0.0085 0.059
Loa Loa (eye worm) acetylcholinesterase 1 0.0069 0.0217 0.0927
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0035 0.0085 0.0129
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0022 0.0022
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.002 0.0148
Trichomonas vaginalis glucose transporter, putative 0.0307 0.1147 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0096 0.0409
Schistosoma mansoni voltage-gated cation channel 0.0154 0.0552 0.1039
Trypanosoma cruzi hexose transporter, putative 0.0307 0.1147 1
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0307 0.1147 0.181
Schistosoma mansoni sodium/solute symporter 0.0076 0.0245 0.0461
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0255 0.0945 0.1491
Schistosoma mansoni inositol transporter 0.0076 0.0245 0.0461
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0022 0.0153
Schistosoma mansoni cytochrome P450 0.0035 0.0085 0.016
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0078 0.0335
Leishmania major cytochrome p450-like protein 0.0052 0.0153 0.1308
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.011 0.0376 0.326
Schistosoma mansoni smad1 5 8 and 0.0017 0.0014 0.0026
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0078 0.0797
Echinococcus granulosus neutral sphingomyelinase 0.0019 0.002 0.0025
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0106 0.0106
Loa Loa (eye worm) transcription factor SMAD2 0.0248 0.0918 0.3926
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0154 0.0552 0.0552
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.015 0.0532 0.5616
Plasmodium falciparum importin beta, putative 0.0057 0.0171 0.147
Echinococcus granulosus pyruvate kinase 0.0033 0.0078 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0106 0.0734
Echinococcus granulosus acetylcholinesterase 0.0069 0.0217 0.027
Toxoplasma gondii cytochrome p450 superfamily protein 0.0035 0.0085 0.0713
Trypanosoma cruzi hypothetical protein, conserved 0.0255 0.0945 0.8238
Onchocerca volvulus 0.0307 0.1147 0.7976
Brugia malayi hypothetical protein 0.0052 0.0152 0.1061
Trypanosoma cruzi trypanothione reductase, putative 0.0028 0.0055 0.0457
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0307 0.1147 1
Plasmodium vivax importin-beta 2, putative 0.0057 0.0171 0.147
Schistosoma mansoni dishevelled 0.0019 0.0021 0.0039
Onchocerca volvulus Huntingtin homolog 0.0139 0.049 0.3394
Echinococcus multilocularis voltage dependent calcium channel 0.0154 0.0552 0.0552
Plasmodium vivax exodeoxyribonuclease III, putative 0.0019 0.002 0.0148
Brugia malayi Pre-SET motif family protein 0.0203 0.074 0.5149
Mycobacterium tuberculosis Probable lipase LipD 0.0255 0.0945 0.1491
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Echinococcus granulosus neuropeptide receptor A26 0.047 0.1787 0.2222
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0022 0.0027
Trypanosoma cruzi hexose transporter, putative 0.0307 0.1147 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0106 0.0106
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0611 0.2337 1
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0106 0.0734
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0106 0.0734
Echinococcus multilocularis pyruvate kinase 0.0017 0.0015 0.0015
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0085 0.0715
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0009 0.0055
Leishmania major fatty acid transporter protein-like protein 0.015 0.0532 0.4627
Echinococcus multilocularis solute carrier family 22 0.0307 0.1147 0.1147
Trypanosoma cruzi hypothetical protein, conserved 0.0255 0.0945 0.8238
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0202 0.0737 0.1162
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0106 0.0199
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0322 0.2806
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0931 0.8116
Echinococcus multilocularis segment polarity protein dishevelled 0.0019 0.0021 0.0021
Echinococcus multilocularis neutral sphingomyelinase 0.0019 0.002 0.002
Trypanosoma cruzi glucose transporter, putative 0.0307 0.1147 1
Schistosoma mansoni alpha-glucosidase 0.0136 0.0481 0.0906
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0322 0.2806
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0014 0.0026
Schistosoma mansoni glucose transport protein 0.0307 0.1147 0.2161
Onchocerca volvulus 0.0255 0.0945 0.657
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0255 0.0945 0.1491
Brugia malayi ecdysteroid receptor 0.004 0.0106 0.0734
Loa Loa (eye worm) hypothetical protein 0.004 0.0106 0.0451
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0055 0.0457
Echinococcus multilocularis beta LACTamase domain containing family member 0.0255 0.0945 0.0945
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0022 0.0027
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0085 0.0866
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0144 0.0179
Trypanosoma cruzi hexose transporter, putative 0.0307 0.1147 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Plasmodium falciparum thioredoxin reductase 0.008 0.0259 0.2236
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0014 0.0058
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0028 0.0055 0.0104
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0028 0.0055 0.0386
Schistosoma mansoni smad1 5 8 and 0.0017 0.0014 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0035 0.0085 0.0129
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0019 0.0023
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0003 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0931 0.8116
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0099 0.0187
Trichomonas vaginalis mercuric reductase, putative 0.0028 0.0055 0.0483
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0086 0.0086
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0022 0.0028
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0031 0.0031
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0112 0.0954
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0035 0.0085 0.0713
Schistosoma mansoni pyruvate kinase 0.0017 0.0015 0.0028
Schistosoma mansoni sugar transporter 0.0307 0.1147 0.2161
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.002 0.0148
Mycobacterium ulcerans esterase/lipase LipP 0.0255 0.0945 0.8238
Echinococcus granulosus muscleblind protein 0.0152 0.0542 0.0674
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0593 0.5168
Brugia malayi DIX domain containing protein 0.0019 0.0021 0.0145
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0085 0.0715
Brugia malayi nuclear receptor RXR 0.0021 0.0031 0.0216
Leishmania major cytochrome p450-like protein 0.0035 0.0085 0.0713
Leishmania major glucose transporter/membrane transporter D2, putative 0.0307 0.1147 1
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0137 0.0259
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0106 0.0451
Schistosoma mansoni cpg binding protein 0.0058 0.0174 0.0328
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0628 0.5471
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0019 0.002 0.0148
Schistosoma mansoni dep domain containing protein 0.0019 0.0021 0.0039
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0078 0.0524
Loa Loa (eye worm) hypothetical protein 0.0255 0.0945 0.4045
Schistosoma mansoni zinc finger protein 0.0019 0.0022 0.0042
Loa Loa (eye worm) hypothetical protein 0.0052 0.0152 0.0652
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0052 0.0428
Echinococcus multilocularis neuropeptide s receptor 0.047 0.1787 0.1787
Toxoplasma gondii NADPH-glutathione reductase 0.0028 0.0055 0.0457
Trichomonas vaginalis conserved hypothetical protein 0.0307 0.1147 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0282 0.1051 0.1981
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0137 0.0137
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0035 0.0085 0.0713
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0009 0.0009
Giardia lamblia hypothetical protein 0.0019 0.002 0.0049
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0035 0.0085 0.0713
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0137 0.0259
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0282 0.1051 0.1981
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0019 0.0137
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0022 0.0093
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0086
Echinococcus granulosus thioredoxin glutathione reductase 0.0081 0.0263 0.0327
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0078 0.0657
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0099 0.0152
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.002 0.0086
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0251 0.0931 0.3983
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0035 0.0085 0.0129
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0028 0.0055 0.0457
Echinococcus multilocularis GPCR, family 2 0.01 0.0338 0.0338
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0019 0.002 0.0148
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0106 0.0106
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0154 0.0552 0.0552
Schistosoma mansoni ap endonuclease 0.0092 0.0307 0.0579
Loa Loa (eye worm) hypothetical protein 0.004 0.0106 0.0451
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0182 0.0658 0.1036
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0035 0.0085 0.0129
Brugia malayi nuclear receptor NHR-88 0.0019 0.0022 0.0153
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0094
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0092 0.0307 0.266
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0216 0.0408
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0035 0.0085 0.0713
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.002 0.014
Echinococcus multilocularis peregrin 0.0033 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0154 0.0552 0.236
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0099 0.084
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0092 0.0307 0.0382
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0094
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0135 0.1175
Onchocerca volvulus Alhambra homolog 0.0029 0.0062 0.0409
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0106 0.0131
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0035 0.0085 0.0129
Loa Loa (eye worm) voltage-dependent calcium channel 0.0043 0.0116 0.0496
Brugia malayi Latrophilin receptor protein 2 0.01 0.0338 0.2353
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0021 0.0089
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.052 0.0979
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.011 0.0376 0.1609
Echinococcus multilocularis mitogen activated protein kinase 0.011 0.0376 0.0376
Brugia malayi Pre-SET motif family protein 0.003 0.0065 0.0455
Loa Loa (eye worm) hypothetical protein 0.004 0.0106 0.0451
Giardia lamblia Hexose transporter 0.0307 0.1147 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.002 0.0148
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0282 0.1051 0.1307
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0055 0.0457
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0009 0.0041
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0028 0.0055 0.0457
Entamoeba histolytica hypothetical protein 0.0255 0.0946 1
Brugia malayi hypothetical protein 0.0019 0.0022 0.0153
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0028 0.0055 0.0457
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0307 0.1147 0.181
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0065 0.0123
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0106 0.0106
Loa Loa (eye worm) major facilitator superfamily transporter 0.0307 0.1147 0.4907
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0099 0.084
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0247 0.2132
Schistosoma mansoni ferritin 0.0018 0.0017 0.0031
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0019 0.002 0.0176
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0022 0.0153
Onchocerca volvulus 0.0307 0.1147 0.7976
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.01 0.0338 0.0338
Trypanosoma cruzi cytochrome P450, putative 0.0052 0.0153 0.1308
Echinococcus multilocularis voltage dependent calcium channel 0.0154 0.0552 0.0552
Leishmania major hypothetical protein, conserved 0.0052 0.0152 0.1305
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0028 0.0055 0.0457
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0322 0.2806
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0062 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Onchocerca volvulus 0.0307 0.1147 0.7976
Brugia malayi glutathione reductase 0.008 0.0259 0.1802
Loa Loa (eye worm) hypothetical protein 0.0307 0.1147 0.4907
Echinococcus granulosus GPCR family 2 0.01 0.0338 0.042
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0092 0.0307 0.3227
Loa Loa (eye worm) hypothetical protein 0.0152 0.0542 0.2319
Trichomonas vaginalis esterase, putative 0.0255 0.0945 0.8243
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0074 0.0236 0.2039
Schistosoma mansoni DNA polymerase eta 0.0039 0.0099 0.0187
Brugia malayi MH2 domain containing protein 0.0017 0.0014 0.0095
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0152 0.1305
Brugia malayi Smad1 0.0017 0.0014 0.0095
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0019 0.0021 0.0145
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0019 0.002 0.0038
Brugia malayi Cytochrome P450 family protein 0.0186 0.0677 0.4709
Brugia malayi hypothetical protein 0.0019 0.0022 0.0156
Loa Loa (eye worm) latrophilin receptor protein 2 0.01 0.0338 0.1447
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0014 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0106 0.0451
Schistosoma mansoni hypothetical protein 0.0255 0.0946 0.1782
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.074 0.3167
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0085 0.0741
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0182 0.0658 0.1036
Loa Loa (eye worm) hypothetical protein 0.0077 0.0247 0.1057
Echinococcus granulosus expressed protein 0.0018 0.0017 0.0021
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0019 0.002 0.0148
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0164 0.1138
Onchocerca volvulus 0.0019 0.0022 0.0134
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0078 0.0657
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Brugia malayi major facilitator superfamily protein 0.0307 0.1147 0.798
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0019 0.002 0.0176
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.002 0.014
Schistosoma mansoni ferritin 0.0018 0.0017 0.0031
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0106 0.0131
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0014
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0019 0.002 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0106 0.0734
Brugia malayi hypothetical protein 0.0307 0.1147 0.798
Schistosoma mansoni hypothetical protein 0.01 0.0338 0.0637
Schistosoma mansoni ran 0.0042 0.0112 0.0212
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0931 0.8116
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0307 0.1147 1
Onchocerca volvulus 0.0307 0.1147 0.7976
Loa Loa (eye worm) Smad1 0.0017 0.0014 0.0058
Onchocerca volvulus 0.0019 0.0022 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0165
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0307 0.1147 0.1147
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0035 0.0085 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0052 0.0428
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0153 0.0654
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.011 0.0376 0.326
Echinococcus multilocularis neuropeptide receptor A26 0.047 0.1787 0.1787
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0322 0.0606
Brugia malayi hypothetical protein 0.0019 0.0021 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0106 0.0734
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0099 0.084
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0106 0.0131
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0376 0.3279
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0107 0.0107
Brugia malayi nuclear receptor RXR 0.0019 0.0022 0.0153
Trichomonas vaginalis D-aminoacylase, putative 0.0255 0.0945 0.8243
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0009 0.0018
Schistosoma mansoni synaptojanin 0.0019 0.002 0.0038
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0019 0.0021 0.0039
Loa Loa (eye worm) hypothetical protein 0.0049 0.0137 0.0588
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0106 0.0199
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0092 0.0307 0.266
Onchocerca volvulus 0.0307 0.1147 0.7976
Brugia malayi N-terminal motif family protein 0.0381 0.1437 1
Echinococcus granulosus smad 0.0017 0.0014 0.0017
Schistosoma mansoni cpg binding protein 0.0061 0.0187 0.0352
Brugia malayi cytochrome P450 0.0035 0.0085 0.059
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0022 0.0153
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0099 0.084
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0028 0.0055 0.0457
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.002 0.014
Schistosoma mansoni inositol transporter 0.0076 0.0245 0.0461
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0247 1
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0078 0.0545
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0065 0.0081
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0099 0.1019
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.0322 0.2786
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0112 0.0112
Loa Loa (eye worm) RNA binding protein 0.0062 0.0191 0.0819
Echinococcus granulosus cytochrome P450 2K1 0.0035 0.0085 0.0105
Onchocerca volvulus 0.0255 0.0945 0.657
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.002 0.0148
Loa Loa (eye worm) cytochrome P450 family protein 0.0186 0.0677 0.2896
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0019 0.002 0.0148
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0028 0.0055 0.0344
Toxoplasma gondii aldehyde dehydrogenase 0.0069 0.0216 0.1863
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0019 0.002 0.018
Brugia malayi mbt repeat family protein 0.0049 0.0137 0.0955
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0019 0.002 0.0176
Leishmania major hypothetical protein, conserved 0.0019 0.002 0.0148
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0542 0.0542
Onchocerca volvulus 0.0307 0.1147 0.7976
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0112 0.0954
Schistosoma mansoni pyruvate kinase 0.0033 0.0078 0.0148
Trichomonas vaginalis set domain proteins, putative 0.023 0.0849 0.7401
Echinococcus granulosus pyruvate kinase 0.0033 0.0078 0.0097
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.002 0.014
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0035 0.0085 0.0129
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0035 0.0085 0.0713
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0019 0.002 0.0148
Brugia malayi Carboxylesterase family protein 0.0069 0.0217 0.1508
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0106 0.0106
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0107 0.0133
Onchocerca volvulus 0.0307 0.1147 0.7976
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0144 0.0223
Onchocerca volvulus 0.0019 0.002 0.0118
Schistosoma mansoni synaptojanin 0.0019 0.002 0.0038
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0062 0.0513
Onchocerca volvulus 0.0307 0.1147 0.7976
Schistosoma mansoni hypothetical protein 0.01 0.0338 0.0637
Echinococcus granulosus tar DNA binding protein 0.0062 0.0191 0.0238
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0028 0.0055 0.0457
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0014
Echinococcus granulosus peregrin 0.0033 0.0076 0.0094
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0116 0.0984
Schistosoma mansoni importin beta-1 0.0057 0.0171 0.0323
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0052 0.0153 0.1308
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0255 0.0945 0.1491
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0106 0.0451
Treponema pallidum hypothetical protein 0.0019 0.002 0.0125
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0282 0.1051 0.7315
Echinococcus granulosus solute carrier family 22 0.0307 0.1147 0.1426
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0078 0.0335
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0094
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0154 0.0552 0.0686
Trypanosoma cruzi trypanothione reductase, putative 0.008 0.0259 0.2236
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0019 0.0138
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0019 0.002 0.018
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0003 0.0028
Brugia malayi nuclear hormone receptor 0.0019 0.0022 0.0153
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0099 0.069
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0019 0.0131
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0069 0.0216 0.1863
Echinococcus granulosus high affinity choline transporter 1 0.0076 0.0245 0.0304
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0154 0.0552 0.0686
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0035 0.0085 0.0713
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0019 0.002 0.018
Brugia malayi hypothetical protein 0.0019 0.0022 0.0156
Onchocerca volvulus 0.0019 0.0022 0.0134
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0028 0.0055 0.0457
Trypanosoma brucei glucose transporter, putative 0.0307 0.1147 1
Onchocerca volvulus 0.0255 0.0945 0.657
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0099 0.084
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0931 0.8116
Entamoeba histolytica hypothetical protein 0.0046 0.0129 0.1335
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0039 0.0039
Echinococcus granulosus importin subunit beta 1 0.0057 0.0171 0.0213
Echinococcus multilocularis high affinity choline transporter 1 0.0076 0.0245 0.0245
Onchocerca volvulus 0.0058 0.0174 0.1191
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0247 1
Echinococcus granulosus Sugar transporter ERD6 protein 0.0307 0.1147 0.1426
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0307 0.1147 0.1426
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0078 0.0657
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0003 0.0022
Echinococcus multilocularis acetylcholinesterase 0.0069 0.0217 0.0217
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0092 0.0307 0.266
Onchocerca volvulus 0.0019 0.0021 0.0123
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0106 0.0451
Trichomonas vaginalis conserved hypothetical protein 0.0307 0.1147 1
Entamoeba histolytica hypothetical protein 0.0025 0.0046 0.0449
Schistosoma mansoni thyroid hormone receptor 0.004 0.0106 0.0199
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0106 0.0199
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0106 0.0199
Brugia malayi Major Facilitator Superfamily protein 0.0307 0.1147 0.798
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0019 0.0021 0.0145
Trichomonas vaginalis glucose transporter, putative 0.0307 0.1147 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0019 0.0137
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0022 0.0168
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0106 0.0106
Schistosoma mansoni ferritin light chain 0.0018 0.0017 0.0031
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0129 0.1125
Trichomonas vaginalis sugar transporter, putative 0.0307 0.1147 1
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0078 0.0657
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0019 0.002 0.002
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0096 0.0322 0.04
Echinococcus granulosus synaptic vesicle 2 protein 0.0307 0.1147 0.1426
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0028 0.0055 0.0055
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0106 0.0734
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0151 0.054 0.4694
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0137 0.0137
Mycobacterium ulcerans integral membrane transport protein 0.0307 0.1147 1
Schistosoma mansoni hypothetical protein 0.0216 0.0791 0.1491
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0191 0.0361
Schistosoma mansoni glucose transport protein 0.0307 0.1147 0.2161
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.002 0.0148
Plasmodium falciparum pyruvate kinase 0.0033 0.0078 0.0657
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0106 0.0199
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0106 0.0199
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0019 0.002 0.0148
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0135 0.1175
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.002 0.0086
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0022 0.0022
Onchocerca volvulus 0.0307 0.1147 0.7976
Onchocerca volvulus Putative transporter 0.0307 0.1147 0.7976

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) Inhibition of bovine liver MAOA ChEMBL. 18834112
Activity (binding) Inhibition of bovine liver MAOB ChEMBL. 18834112

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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