Detailed information for compound 1091540

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 282.695 | Formula: C9H9ClF2N2O2S
  • H donors: 1 H acceptors: 2 LogP: 2.36 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: FC(CN1CNS(=O)(=O)c2c1ccc(c2)Cl)F
  • InChi: 1S/C9H9ClF2N2O2S/c10-6-1-2-7-8(3-6)17(15,16)13-5-14(7)4-9(11)12/h1-3,9,13H,4-5H2
  • InChiKey: ICZUMACHXDOSIN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0111 0.0163
Brugia malayi Retinol dehydrogenase 12 0.0019 0.0061 0.0078
Loa Loa (eye worm) hypothetical protein 0.0021 0.008 0.0101
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0019 0.0061 0.0175
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0067
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0148 0.021
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0061 0.009
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0547 0.1166
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0041 0.0041
Schistosoma mansoni retinal dehydrogenase 0.0019 0.0061 0.0061
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0113 0.1168 0.1713
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0115 0.119 0.1746
Echinococcus granulosus histone deacetylase 6 0.0018 0.0041 0.0041
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0301 0.038
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0019 0.006 0.017
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0113 0.1168 0.2686
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0078
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0073 0.0692 0.0692
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0071 0.0673 0.1917
Schistosoma mansoni histone deacetylase hda2 0.0018 0.0041 0.0041
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0301 0.0301
Trypanosoma cruzi histone deacetylase 1, putative 0.0062 0.0563 0.0826
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0539 0.4383
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.0692 0.1015
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0061 0.0547 0.0802
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0028 0.0165 0.0165
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0301 0.0301
Leishmania major histone deacetylase, putative 0.0062 0.0563 0.0826
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0009 0.0009
Mycobacterium tuberculosis Conserved hypothetical protein 0.0312 0.3511 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0019 0.0061 0.0396
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0374 0.0374
Loa Loa (eye worm) hypothetical protein 0.0018 0.0041 0.0052
Onchocerca volvulus 0.0019 0.0053 0.003
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0175
Brugia malayi bHLH-PAS transcription factor 0.004 0.0308 0.0389
Toxoplasma gondii histone deacetylase HDAC3 0.0062 0.0563 0.4583
Schistosoma mansoni carbonyl reductase 0.0019 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.0113 0.1168 0.1168
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0028 0.0165 0.2384
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0374 0.0374
Echinococcus granulosus histone deacetylase 8 0.0018 0.0041 0.0041
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0061 0.009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0078
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0061 0.009
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0308 0.0452
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0019 0.0061 0.0145
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0061 0.009
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0374 0.4238 1
Schistosoma mansoni hypothetical protein 0.0039 0.0291 0.0291
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0061 0.009
Brugia malayi dehydrogenases, short chain protein 9 0.0019 0.0061 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0078
Leishmania major histone deacetylase, putative 0.0062 0.0563 0.0826
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0041 0.006
Echinococcus granulosus histone deacetylase 6 0.0018 0.0041 0.0041
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0374 0.4238 0.5353
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0024 0.0118 0.1471
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.008 0.0101
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0301 0.038
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0053 0.0053
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0061 0.0004
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0053 0.0053
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0111 0.0168
Schistosoma mansoni histone deacetylase hda2 0.0018 0.0041 0.0041
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0111 0.0317
Schistosoma mansoni histone deacetylase 4 5 0.0018 0.0041 0.0041
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1817 0.4206
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0019 0.0061 0.0049
Echinococcus multilocularis histone deacetylase 3 0.0062 0.0563 0.0563
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0113 0.1168 0.3326
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Onchocerca volvulus 0.0026 0.0143 0.0245
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.2574 0.2574
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0301 0.038
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0301 0.0301
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0061 0.0547 0.1166
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1817 0.4206
Brugia malayi oxidoreductase 0.0019 0.0061 0.0078
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0331 0.5566
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0019 0.0061 0.0396
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0019 0.0061 0.009
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0019 0.0061 0.0061
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0257 0.2857 0.3609
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Entamoeba histolytica hypothetical protein 0.0036 0.0254 0.0598
Onchocerca volvulus 0.0019 0.0061 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0024 0.0036
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0195 0.0324
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0067
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0546 0.069
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0374 0.0374
Echinococcus multilocularis bloom syndrome protein 0.0041 0.0311 0.0311
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0062 0.0563 0.1204
Mycobacterium ulcerans dehydrogenase/reductase 0.0019 0.0061 0.0049
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0113 0.1168 0.2686
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0061 0.0554 0.0699
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0308 0.0638
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0061 0.009
Loa Loa (eye worm) histone deacetylase 1 0.0062 0.0563 0.0711
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0705 0.1035
Leishmania major cytochrome p450-like protein 0.0113 0.1168 0.1713
Trichomonas vaginalis steroid dehydrogenase, putative 0.0019 0.0061 0.0004
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0017 0.0021
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0539 0.0539
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0374 0.0374
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0308 0.0452
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Trypanosoma brucei cytochrome P450, putative 0.0201 0.2205 0.3235
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0041 0.0041
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0111 0.0263
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0301 0.062
Brugia malayi Cytochrome P450 family protein 0.0201 0.2205 0.2785
Onchocerca volvulus 0.0019 0.0061 0.0049
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0061 0.009
Echinococcus granulosus hypothetical protein 0.006 0.0543 0.0543
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0459 0.0955
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0374 0.0374
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0061 0.0061
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0486
Plasmodium falciparum GAF domain-related protein, putative 0.0019 0.006 0.0367
Onchocerca volvulus 0.0019 0.0061 0.0049
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0291 0.0291
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0547 0.1166
Loa Loa (eye worm) hypothetical protein 0.0024 0.0111 0.0141
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0563 0.1204
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0301 0.062
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0061 0.009
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0441 0.0441
Schistosoma mansoni cpg binding protein 0.0064 0.0587 0.0587
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0111 0.0168
Loa Loa (eye worm) oxidoreductase 0.0019 0.0061 0.0078
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.008 0.008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0029 0.0084
Echinococcus multilocularis tumor protein p63 0.0334 0.3763 0.3763
Echinococcus granulosus histone deacetylase 7 0.0018 0.0041 0.0041
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0061 0.0547 0.1166
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0041 0.0116
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0041 0.0041
Trypanosoma brucei unspecified product 0.0034 0.0232 0.034
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0301 0.0301
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0053 0.0067
Brugia malayi Doublecortin family protein 0.0039 0.0291 0.0367
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0441 0.0647
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0019 0.0061 0.0061
Schistosoma mansoni cpg binding protein 0.0064 0.0587 0.0587
Schistosoma mansoni cpg binding protein 0.0061 0.0546 0.0546
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0301 0.038
Schistosoma mansoni cytochrome P450 0.0113 0.1168 0.1168
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0113 0.1168 0.3326
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0539 0.0539
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0113 0.1168 0.3326
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0554 0.0554
Echinococcus granulosus dual specificity protein kinase clk2 0.0061 0.0554 0.0554
Toxoplasma gondii hypothetical protein 0.0019 0.006 0.0473
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0486
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0301 0.038
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0014
Brugia malayi hypothetical protein 0.0036 0.0254 0.032
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0301 0.0301
Echinococcus granulosus cytochrome P450 2K1 0.0113 0.1168 0.1168
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0019 0.0061 0.0014
Schistosoma mansoni single-minded 0.0055 0.0476 0.0476
Loa Loa (eye worm) hypothetical protein 0.0027 0.0148 0.0187
Brugia malayi Dehydrogenases, short chain protein 2 0.0019 0.0061 0.0078
Giardia lamblia Sgs1 DNA helicase, putative 0.0028 0.0165 0.0249
Loa Loa (eye worm) hypothetical protein 0.006 0.0543 0.0685
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0686 0.7917 1
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0014
Brugia malayi hypothetical protein 0.0233 0.2574 0.3252
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0195 0.0287
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0308 0.0452
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0061 0.009
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0175
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0301 0.038
Leishmania major hypothetical protein, conserved 0.0115 0.119 0.1746
Loa Loa (eye worm) CYP4Cod1 0.0201 0.2205 0.2785
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0061 0.009
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0441 0.0912
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0027 0.0148 0.0148
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0061 0.009
Onchocerca volvulus 0.0019 0.0061 0.0049
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.001 0.0015
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0073 0.0692 0.0692
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0049
Schistosoma mansoni histone deacetylase 0.0062 0.0563 0.0563
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0111 0.0168
Brugia malayi hypothetical protein 0.0183 0.1991 0.2514
Loa Loa (eye worm) hypothetical protein 0.0183 0.1991 0.2514
Echinococcus granulosus histone deacetylase 1 0.0062 0.0563 0.0563
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0078
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0301 0.0301
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0002 0.0003
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Entamoeba histolytica short chain dehydrogenase family protein 0.0019 0.0061 0.0145
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.008 0.0101
Echinococcus granulosus microtubule associated protein 2 0.0681 0.786 0.786
Schistosoma mansoni microtubule-associated protein tau 0.0681 0.786 0.786
Brugia malayi nuclear receptor NHR-88 0.0019 0.0053 0.0067
Brugia malayi Cytochrome P450 family protein 0.0284 0.3176 0.4012
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0113 0.1168 0.3326
Mycobacterium ulcerans putative regulatory protein 0.0019 0.006 0.0045
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0301 0.0301
Echinococcus granulosus tumor protein p63 0.0334 0.3763 0.3763
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0308 0.0595
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0061 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0078
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0175
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0061 0.0547 0.0802
Schistosoma mansoni carbonyl reductase 0.0019 0.0061 0.0061
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0374 0.0374
Echinococcus granulosus histone deacetylase 3 0.0062 0.0563 0.0563
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0017 0.0017
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0034 0.0231 0.0231
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0024 0.0036
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0053 0.0053
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0061 0.0145
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Schistosoma mansoni thyroid hormone receptor 0.004 0.0301 0.0301
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0019 0.0061 0.0049
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0049
Entamoeba histolytica recQ family DNA helicase 0.0014 0.0002 0.0004
Trypanosoma cruzi histone deacetylase 1, putative 0.0062 0.0563 0.0826
Brugia malayi tailless protein 0.0019 0.0053 0.0067
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0374 0.4238 1
Entamoeba histolytica histone deacetylase, putative 0.0062 0.0563 0.1329
Trypanosoma brucei histone deacetylase 4 0.0018 0.0041 0.006
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.153 0.153
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0301 0.0301
Schistosoma mansoni rab6-interacting 0.0039 0.0291 0.0291
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0061 0.0061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0301 0.038
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0061 0.0061
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0049
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0061 0.009
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0061 0.0554 0.0812
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Echinococcus multilocularis dnaJ subfamily B 0.0863 1 1
Leishmania major mitochondrial DNA polymerase beta 0.0593 0.6816 1
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0009 0.0009
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0061 0.0061
Schistosoma mansoni coup transcription factor 0.004 0.0301 0.0301
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0113 0.1168 0.2686
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0067
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0071 0.0673 0.1507
Onchocerca volvulus 0.0061 0.0546 0.1204
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.1346 0.1346
Entamoeba histolytica hypothetical protein 0.0036 0.0254 0.0598
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0111 0.0317
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0061 0.009
Schistosoma mansoni polycystin 1-related 0.0039 0.0291 0.0291
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0017 0.0021
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0113 0.1168 0.1713
Echinococcus multilocularis histone deacetylase 7 0.0018 0.0041 0.0041
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0374 0.4238 1
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0254 0.0254
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1924 0.4462
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0061 0.0061
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0301 0.038
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0019 0.0061 0.0004
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0113 0.1168 0.3326
Onchocerca volvulus 0.0019 0.0061 0.0049
Echinococcus granulosus cpg binding protein 0.0064 0.0587 0.0587
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0071 0.0673 0.1507
Brugia malayi ecdysone receptor 0.0019 0.0053 0.0067
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0195 0.0461
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0301 0.0301
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0061 0.0049
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0113 0.1168 0.2686
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0073 0.0692 0.151
Echinococcus multilocularis dual specificity protein kinase clk2 0.0061 0.0554 0.0554
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0547 0.1166
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0061 0.009
Loa Loa (eye worm) oxidoreductase 0.0019 0.0061 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0308 0.0452
Mycobacterium ulcerans putative regulatory protein 0.0019 0.006 0.0045
Echinococcus granulosus WW domain containing oxidoreductase 0.0019 0.0061 0.0061
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0071 0.0673 0.0673
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0019 0.0061 0.0061
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0441 0.0441
Onchocerca volvulus 0.0019 0.0061 0.0049
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0111 0.0892
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0441 0.0441
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0027 0.0148 0.0187
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0074 0.0705 0.0705
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.153 0.1932
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0073 0.0692 0.1633
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0061 0.009
Entamoeba histolytica hypothetical protein 0.0019 0.0061 0.0145
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0061 0.0547 0.0802
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0074 0.0705 0.0891
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0053 0.0067
Brugia malayi Histone deacetylase 1 0.0062 0.0563 0.0711
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0308 0.0452
Leishmania major cytochrome p450-like protein 0.0113 0.1168 0.1713
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0308 0.0452
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0441 0.0912
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0301 0.038
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0019 0.0061 0.0175
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Brugia malayi nuclear receptor RXR 0.0019 0.0053 0.0067
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0073 0.0692 0.0692
Schistosoma mansoni hypothetical protein 0.0863 1 1
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0019 0.0061 0.0061
Plasmodium vivax steroid dehydrogenase, putative 0.0019 0.0061 0.0396
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0019 0.0061 0.009
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0113 0.1168 0.3326
Leishmania major pteridine reductase 1 0.0019 0.0061 0.009
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0374 0.4238 1
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.2857 0.6696
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0061 0.0145
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0195 0.0287
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Loa Loa (eye worm) dehydrogenase 0.0019 0.0061 0.0078
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0111 0.0141
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0073 0.0692 0.1015
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0031 0.0193 0.0243
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0061 0.0554 0.4505
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0374 0.0472
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0111 0.0168
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0019 0.0061 0.0014
Toxoplasma gondii cytochrome p450 superfamily protein 0.0113 0.1168 0.9523
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.2857 0.6696
Onchocerca volvulus 0.0019 0.0061 0.0049
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0019 0.0061 0.0004
Mycobacterium ulcerans oxidoreductase 0.0019 0.0061 0.0049
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0061 0.0061
Loa Loa (eye worm) cytochrome P450 family protein 0.0201 0.2205 0.2785
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0019 0.0061 0.0175
Echinococcus multilocularis conserved hypothetical protein 0.0019 0.0061 0.0061
Leishmania major DNA polymerase kappa, putative 0.0021 0.0077 0.0112
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0061 0.009
Brugia malayi hypothetical protein 0.0025 0.0131 0.0165
Toxoplasma gondii hypothetical protein 0.0053 0.0459 0.3733
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0441 0.0909
Loa Loa (eye worm) hypothetical protein 0.0088 0.0869 0.1098
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0441 0.0557
Leishmania major short chain dehydrogenase, putative 0.0019 0.0061 0.009
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0232 0.034
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.0692 0.1015
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0301 0.0301
Echinococcus granulosus GPCR family 2 0.0016 0.0017 0.0017
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0061 0.0547 0.1166
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0061 0.0547 0.0547
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0061 0.009
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0301 0.038
Brugia malayi hypothetical protein 0.0021 0.008 0.0101
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0291 0.479
Brugia malayi dehydrogenases, short chain protein 2 0.0019 0.0061 0.0078
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0074 0.0705 0.0891
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0539 0.1186
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0019 0.0061 0.0061
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0563 0.1204
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0113 0.1168 0.3326
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0441 0.0912
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0291 0.0291
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0113 0.1168 0.3326
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0074 0.0705 0.0705
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0049
Echinococcus multilocularis 0.0113 0.1168 0.1168
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0061 0.0061
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0019 0.0061 0.009
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0441 0.0441
Echinococcus multilocularis histone deacetylase 8 0.0018 0.0041 0.0041
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0061 0.0061
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0029 0.0084
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Echinococcus granulosus steroid dehydrogenase 0.0019 0.0061 0.0061
Schistosoma mansoni histone deacetylase 1 2 3 0.0018 0.0041 0.0041
Entamoeba histolytica hypothetical protein 0.0036 0.0254 0.0598
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0554 0.0554
Schistosoma mansoni nuclear receptor 0.0019 0.0053 0.0053
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0017 0.0021
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0061 0.0145
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1817 0.4206
Plasmodium falciparum histone deacetylase 1 0.0062 0.0563 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0692 0.0874
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0301 0.0301
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0073 0.0692 0.0692
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0071 0.0673 0.0673
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0131 0.0192
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0061 0.009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0041 0.0052
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0301 0.038
Entamoeba histolytica short chain dehydrogenase family protein 0.0019 0.0061 0.0145
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.029 0.4769
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0073 0.0692 0.0692
Brugia malayi MH2 domain containing protein 0.012 0.1246 0.1573
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0291 0.479
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0019 0.0061 0.0061
Onchocerca volvulus 0.0024 0.0111 0.0169
Schistosoma mansoni thyroid hormone receptor 0.004 0.0301 0.0301
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0257 0.2857 0.3609
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0041 0.0003
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0061 0.0175
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0061 0.0554 0.0812
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.2857 0.6696
Loa Loa (eye worm) hypothetical protein 0.0018 0.0041 0.0052
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0067
Brugia malayi histone deacetylase 3 (HD3) 0.0062 0.0563 0.0711
Onchocerca volvulus 0.0019 0.0061 0.0049
Mycobacterium tuberculosis Probable dehydrogenase 0.0019 0.0061 0.0175
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Trypanosoma brucei protein kinase, putative 0.0052 0.0441 0.0647
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0301 0.0301
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0308 0.0452
Toxoplasma gondii histone deacetylase HDAC2 0.0062 0.0563 0.4583
Schistosoma mansoni carbonyl reductase 0.0019 0.0061 0.0061
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0441 0.3585
Schistosoma mansoni zinc finger protein 0.0019 0.0053 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0308 0.0452
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0041 0.0052
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0061 0.0175
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0053 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0024 0.0036
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0165 0.1334
Leishmania major protein kinase, putative 0.0015 0.001 0.0015
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0019 0.0061 0.0145
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0019 0.0061 0.0061
Entamoeba histolytica hypothetical protein 0.0036 0.0254 0.0598
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0563 0.1204
Loa Loa (eye worm) hypothetical protein 0.0039 0.0291 0.0367
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0113 0.1168 0.3326
Leishmania major cytochrome p450-like protein 0.0201 0.2205 0.3235
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0301 0.038
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0061 0.009
Brugia malayi polk-prov protein 0.0031 0.0193 0.0243
Echinococcus granulosus hypothetical protein 0.0019 0.0061 0.0061
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0053 0.0067
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0111 0.0163
Loa Loa (eye worm) hypothetical protein 0.0021 0.008 0.0101
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0053 0.0053
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.008 0.008
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0061 0.009
Onchocerca volvulus 0.004 0.0308 0.0638
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Toxoplasma gondii hypothetical protein 0.0019 0.006 0.0473
Onchocerca volvulus 0.004 0.0301 0.062
Loa Loa (eye worm) hypothetical protein 0.0018 0.0041 0.0051
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0061 0.0061
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0061 0.0554 0.0812
Brugia malayi hypoxia-induced factor 1 0.0169 0.1823 0.2303
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.1817 0.4232
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0061 0.0547 0.0802
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0331 0.065
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0009 0.0009
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0041 0.0319 0.0621
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0053 0.003
Loa Loa (eye worm) DR-78 0.0019 0.0053 0.0067
Onchocerca volvulus 0.0019 0.0061 0.0049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0301 0.0301
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0441 0.0912
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0291 0.0291
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.038
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0175
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0019 0.0061 0.5
Onchocerca volvulus 0.0019 0.0061 0.0049
Loa Loa (eye worm) hypothetical protein 0.0039 0.0291 0.0367
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0291 0.0291
Mycobacterium ulcerans oxidoreductase 0.0019 0.0061 0.0049
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0061 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0301 0.038
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0053 0.0053
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0171 0.1846 0.1846
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0061 0.0004
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0028 0.0165 0.0165
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0113 0.1168 0.2686
Brugia malayi MAP kinase sur-1 0.0052 0.0441 0.0557
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.028 0.3138 0.4603
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.1246 0.1573
Brugia malayi Cytochrome P450 family protein 0.0113 0.1168 0.1475
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.2857 0.6696
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0111 0.0141
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0113 0.1168 0.1713
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0374 0.0472
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0053 0.0053
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0062 0.0563 0.1204
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0028 0.0165 0.0165
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Mycobacterium ulcerans putative regulatory protein 0.004 0.0308 0.0637
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0061 0.0061
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0061 0.0004
Leishmania major hypothetical protein, conserved 0.0019 0.0061 0.009
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0301 0.038
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.0141 0.0141
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0061 0.0554 0.0812
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0113 0.1168 0.2686
Echinococcus multilocularis microtubule associated protein 2 0.0681 0.786 0.786
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0053 0.0067
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0028 0.0165 0.0209
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0061 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0113 0.1168 0.3326
Brugia malayi hypothetical protein 0.0019 0.0061 0.0078
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0115 0.119 0.2706
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0074 0.0705 0.1664
Loa Loa (eye worm) hypothetical protein 0.0027 0.0148 0.0187
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0061 0.0547 0.0802
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0053 0.0053
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0331 0.2691
Loa Loa (eye worm) histone deacetylase 7A 0.0018 0.0041 0.0051
Toxoplasma gondii GAF domain-containing protein 0.0019 0.006 0.0473
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0053 0.0053
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0165 0.0209
Brugia malayi Protein kinase domain containing protein 0.0061 0.0554 0.0699
Plasmodium vivax hypothetical protein, conserved 0.0019 0.006 0.0367
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0131 0.1051
Schistosoma mansoni DNA helicase recq1 0.0028 0.0165 0.0165
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0486
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0301 0.0301
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0254 0.0254
Schistosoma mansoni rab6-interacting 0.0039 0.0291 0.0291
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0131 0.0192
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0027 0.0148 0.0148
Echinococcus multilocularis 0.006 0.0543 0.0543
Loa Loa (eye worm) hypoxia-induced factor 1 0.0169 0.1823 0.2303
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0441 0.0647
Loa Loa (eye worm) oxidoreductase 0.0019 0.0061 0.0078
Loa Loa (eye worm) hypothetical protein 0.0034 0.0231 0.0292
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0331 0.065
Loa Loa (eye worm) oxidoreductase 0.0019 0.0061 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1817 0.4206
Brugia malayi Histone deacetylase family protein 0.0018 0.0041 0.0051
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.153 0.153
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0692 0.1513
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0061 0.009
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0021 0.008 0.0101
Toxoplasma gondii carbonyl reductase 1, putative 0.0019 0.0061 0.0486
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0102 0.1029 0.151
Loa Loa (eye worm) oxidoreductase 0.0019 0.0061 0.0078
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0113 0.1168 0.3326
Loa Loa (eye worm) hypothetical protein 0.0025 0.0131 0.0165
Schistosoma mansoni hypothetical protein 0.0016 0.0017 0.0017
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.001 0.0015
Brugia malayi Histone deacetylase family protein 0.0018 0.0041 0.0051
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0049
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0233 0.2574 0.3252
Mycobacterium ulcerans carveol-like dehydrogenase 0.0019 0.0061 0.0049
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0061 0.0547 0.0547
Onchocerca volvulus 0.0049 0.0408 0.0874
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0171 0.1846 0.1846
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0067
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0486
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0593 0.6816 1
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0061 0.0061
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0061 0.009
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.038
Leishmania major short chain dehydrogenase-like protein 0.0019 0.0061 0.009
Giardia lamblia Kinase, CMGC CLK 0.0061 0.0554 0.1178
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0053 0.0067
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.028 0.3138 0.4603
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Schistosoma mansoni lipoxygenase 0.0101 0.1021 0.1021
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0061 0.0049
Loa Loa (eye worm) oxidoreductase 0.0019 0.0061 0.0078
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0539 0.1186
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0301 0.038
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0441 0.0647
Leishmania major hypothetical protein, conserved 0.0019 0.0061 0.009
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0165 0.0209
Plasmodium falciparum protein serine/threonine kinase-1 0.0061 0.0554 0.9817
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0113 0.1168 0.2686
Loa Loa (eye worm) histone deacetylase 11 0.0018 0.0041 0.0051
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0078
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0061 0.0175
Brugia malayi hypothetical protein 0.0019 0.0053 0.0067
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0061 0.0175
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0053 0.0067
Schistosoma mansoni blooms syndrome DNA helicase 0.0014 0.0002 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Onchocerca volvulus 0.0019 0.0061 0.0049
Loa Loa (eye worm) oxidoreductase 0.0019 0.0061 0.0078
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0024 0.0111 0.0141
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0113 0.1168 0.3326
Schistosoma mansoni hypothetical protein 0.0016 0.0017 0.0017
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0053 0.0053
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0029 0.0084
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0061 0.0004
Loa Loa (eye worm) histone deacetylase 0.0018 0.0041 0.0051
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0301 0.038
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0111 0.0168
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0391 0.0494
Schistosoma mansoni hypothetical protein 0.0016 0.0017 0.0017
Brugia malayi Bloom's syndrome protein homolog 0.0041 0.0311 0.0393
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0061 0.0061
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0071 0.0673 0.085
Leishmania major protein kinase, putative 0.0061 0.0554 0.0812
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0547 0.1166
Mycobacterium ulcerans hypothetical protein 0.0312 0.3511 0.8268
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0111 0.0263
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0111 0.0263
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0539 0.0539
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0301 0.0301
Trypanosoma cruzi hypothetical protein, conserved 0.0115 0.119 0.1746
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0028 0.0165 0.0165
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0113 0.1168 0.3326
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0308 0.0452
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Brugia malayi hypothetical protein 0.0019 0.0061 0.0078
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0547 0.1166
Schistosoma mansoni nuclear receptor 0.0019 0.0053 0.0053
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0019 0.0061 0.0061
Schistosoma mansoni aryl hydrocarbon receptor 0.0055 0.0476 0.0476
Leishmania major 3-keto-dihydrosphingosine reductase 0.0019 0.0061 0.009
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0111 0.0141
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0061 0.009
Schistosoma mansoni loxhd1 0.0039 0.0291 0.0291
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0061 0.009
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0041 0.5
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0374 0.4238 1
Echinococcus multilocularis histone deacetylase 0.0018 0.0041 0.0041
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0061 0.009
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0061 0.0175
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0061 0.0049
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0301 0.0301
Trichomonas vaginalis DNA helicase recq, putative 0.0041 0.0311 0.0601
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0113 0.1168 0.2686
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0301 0.0301
Leishmania major hypothetical protein, conserved 0.0019 0.0061 0.009
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0061 0.0061
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0113 0.1168 0.2686
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0308 0.0452
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0193 0.0283
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0078
Trypanosoma brucei histone deacetylase 1 0.0062 0.0563 0.0826
Brugia malayi PAS domain containing protein 0.0055 0.0476 0.0601
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0301 0.0301
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0061 0.0554 0.0812
Brugia malayi ecdysteroid receptor 0.004 0.0301 0.038
Schistosoma mansoni histone deacetylase 0.0062 0.0563 0.0563
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0111 0.0465
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0374 0.4238 0.5353
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0053 0.0053
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0061 0.0547 0.1166
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0301 0.038
Trypanosoma brucei histone deacetylase 2 0.0018 0.0041 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1817 0.4206
Toxoplasma gondii histone deacetylase HDAC1 0.0018 0.0041 0.0317
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0062 0.0563 0.0711
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0337 0.0337
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0301 0.062
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0441 0.0647
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0019 0.0061 0.009
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0061 0.0061
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0061 0.0049
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0374 0.4238 1
Loa Loa (eye worm) acetyltransferase 0.0144 0.153 0.1932
Mycobacterium leprae Conserved hypothetical protein 0.0113 0.1168 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0067
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0077 0.0218
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0019 0.0061 0.0049
Plasmodium falciparum steroid dehydrogenase, putative 0.0019 0.0061 0.0396
Leishmania major short chain dehydrogenase, putative 0.0019 0.0061 0.009
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0331 0.0331
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Onchocerca volvulus Sepiapterin reductase homolog 0.0019 0.0061 0.0049
Mycobacterium ulcerans short-chain type oxidoreductase 0.0019 0.0061 0.0049
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.038
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.1482 0.1482
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0061 0.0486
Loa Loa (eye worm) RecQ helicase 0.0041 0.0311 0.0393
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0041 0.006
Schistosoma mansoni survival motor neuron protein 0.0047 0.0391 0.0391
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.0814 0.1194
Brugia malayi cytochrome P450 0.0113 0.1168 0.1475
Onchocerca volvulus 0.0374 0.4238 1
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0061 0.0175
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0301 0.0301
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0308 0.0308
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0067
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0041 0.0319 0.0621
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0019 0.0061 0.0175
Onchocerca volvulus 0.0019 0.0061 0.0049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0301 0.038
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0067
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0009 0.0009
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Schistosoma mansoni lipoxygenase 0.0171 0.1846 0.1846
Brugia malayi nuclear hormone receptor 0.004 0.0301 0.038
Schistosoma mansoni hypothetical protein 0.0047 0.0391 0.0391
Echinococcus multilocularis GPCR, family 2 0.0016 0.0017 0.0017
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0053 0.003
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0053 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0113 0.1168 0.3326
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0053 0.0053
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0301 0.0301
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0019 0.0061 0.0049
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0441 0.0647
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0061 0.0547 0.1166
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0111 0.0465
Trichomonas vaginalis DNA helicase recq1, putative 0.0041 0.0311 0.0601
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0061 0.0061
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.2574 0.2574
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0111 0.0163
Brugia malayi hypothetical protein 0.0039 0.0291 0.0367
Brugia malayi nuclear receptor NHR-67 0.0019 0.0053 0.0067
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0148 0.021
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0374 0.4238 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0041 0.0052
Giardia lamblia Histone deacetylase 0.0062 0.0563 0.1201
Echinococcus granulosus hypothetical protein 0.0019 0.0061 0.0061
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0113 0.1168 0.2686
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0021
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0061 0.0061
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0078
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0053 0.0067
Loa Loa (eye worm) histone deacetylase 3 0.0062 0.0563 0.0711
Schistosoma mansoni DNA helicase recq5 0.0028 0.0165 0.0165
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0061 0.0061
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0113 0.1168 0.2686
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0041 0.006
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0113 0.1168 0.2686
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.008 0.008
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0113 0.1168 0.2686
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0459 0.0955
Schistosoma mansoni nuclear hormone receptor 0.004 0.0301 0.0301
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0053 0.0067
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.001 0.0015
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.001 0.0015
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0113 0.1168 0.2686
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0077 0.0112
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0019 0.006 0.0076
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0019 0.0061 0.0078
Loa Loa (eye worm) cytochrome P450 0.0113 0.1168 0.1475
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0053 0.0053
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0113 0.1168 0.2686
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Leishmania major hypothetical protein, conserved 0.0019 0.0061 0.009
Brugia malayi CXXC zinc finger family protein 0.0061 0.0546 0.069
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0175
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0061 0.0175
Leishmania major histone deacetylase, putative 0.0018 0.0041 0.006
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0113 0.1168 0.3326
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0019 0.0061 0.0486
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.1226 1
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0195 0.0287
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0539 0.079
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0061 0.0049
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0067
Brugia malayi hypothetical protein 0.0016 0.0025 0.0031
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0563 0.1204
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.1246 0.1573
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0073 0.0692 0.0874
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0593 0.6816 1
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0113 0.1168 0.3326
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0301 0.038
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0061 0.009
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0053 0.0053
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0291 0.0291
Toxoplasma gondii histone deacetylase HDAC5 0.0018 0.0041 0.0317
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Loa Loa (eye worm) hypothetical protein 0.0021 0.008 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0301 0.038
Echinococcus granulosus ubiquitin specific protease 41 0.0073 0.0692 0.0692
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0074 0.0705 0.1035
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0113 0.1168 0.3326
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0111 0.0168
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0554 0.1182
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0074 0.0705 0.0705
Treponema pallidum ATP-dependent DNA helicase 0.0014 0.0002 0.5
Echinococcus multilocularis histone deacetylase 1 0.0062 0.0563 0.0563
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.0016 0.0017 0.0017
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0113 0.1168 0.3326
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0113 0.1168 0.2686
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0113 0.1168 0.3326
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.029 0.0684
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0019 0.0061 0.0049
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0301 0.038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0029 0.0084
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0301 0.0301
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0416 0.0526
Leishmania major oxidoreductase-like protein 0.0019 0.0061 0.009
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0201 0.2205 0.5157
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0113 0.1168 0.1713
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0563 0.1204
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0441 0.0647
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0113 0.1168 0.2686
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0019 0.0061 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0459 0.0955
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0301 0.0301
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0077 0.0112
Loa Loa (eye worm) hypothetical protein 0.0024 0.0111 0.0141
Brugia malayi follicle stimulating hormone receptor 0.0686 0.7917 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0053 0.0053
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0705 0.1035
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0374 0.4238 1
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0019 0.0061 0.0049
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.2857 0.6696
Loa Loa (eye worm) cytochrome P450 family protein 0.0284 0.3176 0.4012
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0301 0.038
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0073 0.0692 0.0692
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0019 0.0061 0.0078
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0539 0.1534
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0061 0.0004
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0416 0.0526
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0061 0.0145
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0593 0.6816 1
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0019 0.006 0.0045
Leishmania major protein kinase, putative 0.0061 0.0554 0.0812
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0259 0.288 0.8202
Onchocerca volvulus 0.0039 0.0291 0.0596
Loa Loa (eye worm) hypothetical protein 0.005 0.0416 0.0526
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0308 0.0452
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0073 0.0692 0.1513
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0019 0.0061 0.009
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0019 0.0061 0.0014
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0061 0.0175
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0061 0.009
Onchocerca volvulus 0.0039 0.0291 0.0596
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0067
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0061 0.0049
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0019 0.0061 0.0004
Echinococcus granulosus RUN 0.0039 0.0291 0.0291
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.038
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0165 0.1334
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0281 0.4597
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0061 0.0061
Loa Loa (eye worm) dehydrogenase 0.0019 0.0061 0.0078
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.029 0.0547
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0113 0.1168 0.2686
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0331 0.2691
Brugia malayi conserved hypotetical protein 0.0019 0.0053 0.0067
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0131 0.0192
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0041 0.0003
Echinococcus granulosus FTZ F1 alpha 0.004 0.0301 0.0301
Mycobacterium ulcerans dehydrogenase 0.0019 0.0061 0.0049
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0073 0.0692 0.1513
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.005 0.0063
Loa Loa (eye worm) cytochrome P450 family protein 0.0201 0.2205 0.2785
Echinococcus granulosus histone deacetylase 0.0018 0.0041 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0061 0.009
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0175
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.0692 0.1015
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0113 0.1168 0.1713
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0308 0.0452
Trypanosoma cruzi cytochrome P450, putative 0.0201 0.2205 0.3235
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.038
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0539 0.0539
Leishmania major hypothetical protein, conserved 0.0025 0.0131 0.0192
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0019 0.0061 0.0078
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0053 0.0067
Mycobacterium ulcerans hypothetical protein 0.0024 0.0111 0.0168
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0705 0.1035
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0131 0.1721
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0301 0.0301
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0408 0.0408
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Loa Loa (eye worm) hypothetical protein 0.0021 0.008 0.0101
Echinococcus granulosus oxidoreductase 0.0019 0.0061 0.0061
Brugia malayi hypothetical protein 0.0019 0.0053 0.0067
Onchocerca volvulus 0.0019 0.0053 0.003
Trypanosoma brucei histone deacetylase 3 0.0018 0.0041 0.006
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.038
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0061 0.009
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0441 0.0647
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0061 0.0554 0.0812
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0308 0.0638
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0019 0.0061 0.0175
Onchocerca volvulus 0.0047 0.0391 0.0836
Trypanosoma brucei histone deacetylase, putative 0.0018 0.0041 0.006
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0061 0.0175
Schistosoma mansoni histone deacetylase 4 5 0.0018 0.0041 0.0041
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0254 0.0254
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Echinococcus multilocularis RUN 0.0039 0.0291 0.0291
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0444 0.0561
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0301 0.0301
Leishmania major histone deacetylase, putative 0.0018 0.0041 0.006
Trichomonas vaginalis histone deacetylase, putative 0.0062 0.0563 0.1204
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0019 0.0061 0.0486
Echinococcus granulosus bloom syndrome protein 0.0041 0.0311 0.0311
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.2857 0.6696
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0017 0.0017
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0061 0.009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0374 0.0374
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0061 0.009
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0041 0.006
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.0148 0.0187
Brugia malayi hypothetical protein 0.0021 0.008 0.0101
Echinococcus granulosus single minded 2 0.004 0.0308 0.0308
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.0078
Brugia malayi histone deacetylase 11 0.0018 0.0041 0.0051
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0291 0.0367
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0062 0.0563 0.1204
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0019 0.0061 0.0175
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0374 0.4238 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0148 0.021
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0083 0.0814 0.1194
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0441 0.0441
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0053 0.0053
Brugia malayi nuclear hormone receptor 0.0019 0.0053 0.0067
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0061 0.009
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0017 0.0017
Brugia malayi nuclear receptor NHR-88 0.004 0.0301 0.038
Echinococcus multilocularis retinol dehydrogenase 13 0.0019 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0067
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0061 0.0547 0.0547
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0049
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0049
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0308 0.0452
Echinococcus multilocularis oxidoreductase 0.0019 0.0061 0.0061
Brugia malayi hypothetical protein 0.0039 0.0291 0.0367
Schistosoma mansoni hypothetical protein 0.0036 0.0254 0.0254
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0061 0.0061
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0061 0.0547 0.1166
Brugia malayi histone deacetylase 1 (HD1) 0.0062 0.0563 0.0711
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0061 0.0396
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0061 0.0547 0.1166
Mycobacterium leprae putative cytochrome p450 0.0113 0.1168 1
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0115 0.119 0.2706
Giardia lamblia DINP protein human, muc B family 0.0021 0.0077 0.0036
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0083 0.0814 0.1194
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0113 0.1168 0.2686
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0061 0.0175
Brugia malayi Cytochrome P450 family protein 0.0201 0.2205 0.2785
Trypanosoma cruzi hypothetical protein, conserved 0.0115 0.119 0.1746
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0061 0.009
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0061 0.0486
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0061 0.0145
Brugia malayi steroid hormone receptor 0.004 0.0301 0.038
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0231 0.0292
Loa Loa (eye worm) oxidoreductase 0.0019 0.0061 0.0078
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.028 0.3138 0.4603
Loa Loa (eye worm) oxidoreductase 0.0019 0.0061 0.0078
Trypanosoma brucei oxidoreductase-like protein 0.0019 0.0061 0.009
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0291 0.0291
Echinococcus granulosus histone deacetylase 6 0.0018 0.0041 0.0041
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0416 0.0526
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0061 0.0049
Leishmania major dehydrogenase-like protein 0.0019 0.0061 0.009
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0131 0.1721
Echinococcus multilocularis ubiquitin specific protease 41 0.0073 0.0692 0.0692
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0113 0.1168 0.3326
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0071 0.0673 0.0988
Plasmodium vivax histone deacetylase 1, putative 0.0062 0.0563 1
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0061 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0301 0.038
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0019 0.006 0.017
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.038
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0111 0.0168
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0041 0.006
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0041 0.0319 0.0468
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0061 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0165 0.0209
Toxoplasma gondii hypothetical protein 0.0096 0.0959 0.7814
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.0814 0.1194
Toxoplasma gondii histone deacetylase HDAC4 0.0018 0.0041 0.0317
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.038
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0027 0.0148 0.0148
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1924 0.4462
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0019 0.0061 0.009
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0486
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0019 0.0061 0.0175
Mycobacterium leprae Probable oxidoreductase 0.0019 0.0061 0.0014
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0113 0.1168 0.2686
Plasmodium vivax serine/threonine kinase-1, putative 0.0061 0.0554 0.9817
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0019 0.0061 0.0061
Echinococcus multilocularis cpg binding protein 0.0064 0.0587 0.0587
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1817 0.4206
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0308 0.0452
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.008 0.0101
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0061 0.009
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0019 0.0061 0.0175
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0061 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0539 0.1186
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0053 0.0067
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0061 0.0078
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0061 0.0547 0.1166
Leishmania major hypothetical protein, conserved 0.0019 0.0061 0.009
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0061 0.0049
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0337 0.0337
Loa Loa (eye worm) hypothetical protein 0.0049 0.0408 0.0515
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0193 0.0283
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0061 0.009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0067
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0019 0.0061 0.0486
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0131 0.1721
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0019 0.0061 0.0049
Trypanosoma cruzi cytochrome P450, putative 0.0201 0.2205 0.3235
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0071 0.0673 0.0673
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0308 0.0452
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0061 0.009
Brugia malayi nuclear receptor RXR 0.0021 0.008 0.0101
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0374 0.4238 1
Brugia malayi Dehydrogenases, short chain protein 30 0.0019 0.0061 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0067
Echinococcus multilocularis dna polymerase kappa 0.004 0.0308 0.0308
Echinococcus granulosus dna polymerase kappa 0.004 0.0308 0.0308
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0009 0.0009
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0061 0.0061
Leishmania major protein kinase, putative 0.0015 0.001 0.0015
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0308 0.0595
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0301 0.038
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0019 0.0061 0.0061
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0061 0.0061
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0019 0.0061 0.0175
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0061 0.0061
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1817 0.4206

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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