Detailed information for compound 1298788

Basic information

Technical information
  • TDR Targets ID: 1298788
  • Name: 2-(2,4-dichlorophenoxy)-N-[4-(4-methylpiperaz in-1-yl)phenyl]acetamide
  • MW: 394.295 | Formula: C19H21Cl2N3O2
  • H donors: 1 H acceptors: 1 LogP: 3.99 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1CCN(CC1)c1ccc(cc1)NC(=O)COc1ccc(cc1Cl)Cl
  • InChi: 1S/C19H21Cl2N3O2/c1-23-8-10-24(11-9-23)16-5-3-15(4-6-16)22-19(25)13-26-18-7-2-14(20)12-17(18)21/h2-7,12H,8-11,13H2,1H3,(H,22,25)
  • InChiKey: OILQRYVUKMDUKO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(2,4-dichlorophenoxy)-N-[4-(4-methyl-1-piperazinyl)phenyl]acetamide
  • 2-(2,4-dichlorophenoxy)-N-[4-(4-methylpiperazin-1-yl)phenyl]ethanamide
  • MLS000081245
  • SMR000043666
  • STK254751

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens hydroxysteroid (17-beta) dehydrogenase 10 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Cryptosporidium parvum scully CG7113-PA, putative Get druggable targets OG5_129031 All targets in OG5_129031
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania braziliensis 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma japonicum ko:K00022 3-hydroxyacyl-CoA dehydrogenase [EC1.1.1.35], putative Get druggable targets OG5_129031 All targets in OG5_129031
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Cryptosporidium hominis scully CG7113-PA Get druggable targets OG5_129031 All targets in OG5_129031
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania infantum 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania donovani 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania mexicana 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase hydroxysteroid (17-beta) dehydrogenase 10 252 aa 251 aa 24.7 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) oxidoreductase 0.0009 0.0006 0.0019
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.048 0.25
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0133 0.0241
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0011 0.0019 0.0034
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Echinococcus granulosus replication factor c subunit 1 0.001 0.0012 0.0013
Leishmania major histidyl-tRNA synthetase, putative 0.0011 0.0019 0.029
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0014 0.0046
Echinococcus granulosus ferritin 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0046
Echinococcus granulosus lamin 0.0027 0.0121 0.0133
Echinococcus granulosus zinc finger protein 0.0009 0.0006 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0011 0.0018 0.002
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0011 0.0019 0.0097
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Schistosoma mansoni tar DNA-binding protein 0.007 0.0393 0.0433
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0009 0.0006 0.0087
Brugia malayi isocitrate dehydrogenase 0.0016 0.0051 0.0169
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0096 0.0558 0.1844
Onchocerca volvulus 0.0009 0.0006 0.0038
Loa Loa (eye worm) hypothetical protein 0.0033 0.0161 0.0532
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0085 0.0085
Trichomonas vaginalis inositol monophosphatase, putative 0.0073 0.041 0.2133
Plasmodium falciparum histone acetyltransferase GCN5 0.0077 0.0436 0.0522
Echinococcus multilocularis expressed protein 0.0009 0.0007 0.0007
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0008 0.0026
Loa Loa (eye worm) RNA binding protein 0.007 0.0393 0.1301
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0009 0.0007 0.0023
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0088 0.0088
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.006 0.0198
Trypanosoma brucei short-chain dehydrogenase, putative 0.0009 0.0006 0.0087
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0094 0.0543 0.1794
Echinococcus multilocularis asparaginyl tRNA synthetase 0.0011 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.019 0.099
Entamoeba histolytica aspartyl-tRNA synthetase, putative 0.0011 0.0018 0.0328
Onchocerca volvulus Sepiapterin reductase homolog 0.0009 0.0006 0.0038
Plasmodium vivax lysine--tRNA ligase, putative 0.007 0.0391 0.0469
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0078 0.0443 0.0487
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.007 0.0391 0.6112
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0009 0.0006 0.0062
Echinococcus multilocularis retinol dehydrogenase 13 0.0009 0.0006 0.0006
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0014 0.0015
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0051 0.08
Plasmodium falciparum calcium-dependent protein kinase 1 0.0096 0.0558 0.0669
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0009 0.0006 0.0029
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0011 0.0018 0.0018
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0085 0.0094
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0084 0.048 0.087
Schistosoma mansoni smad1 5 8 and 0.0017 0.006 0.0066
Brugia malayi ecdysteroid receptor 0.001 0.0014 0.0046
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0367 0.1212
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0018 0.0063 0.1126
Schistosoma mansoni hypothetical protein 0.0033 0.0161 0.0177
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0009 0.0006 0.0087
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0099 0.0515
Echinococcus multilocularis snurportin 1 0.0308 0.1885 0.1885
Schistosoma mansoni lysyl-tRNA synthetase 0.007 0.0391 0.043
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0009 0.0006 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0014 0.0046
Leishmania major asparaginyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0011 0.0019 0.0205
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.007 0.0391 0.2038
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.011 0.0641 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0044 0.0229 0.0252
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0006 0.0087
Echinococcus multilocularis transient receptor potential cation channel 0.0009 0.0006 0.0006
Toxoplasma gondii aspartate-tRNA ligase 0.0011 0.0018 0.0033
Treponema pallidum aspartyl-tRNA synthetase 0.0011 0.0018 0.0267
Leishmania major oxidoreductase-like protein 0.0009 0.0006 0.0087
Mycobacterium ulcerans acetylornithine aminotransferase 0.0022 0.0088 0.0968
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.031 0.4834
Schistosoma mansoni nuclear hormone receptor 0.001 0.0014 0.0015
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0313 0.1921 0.1921
Trichomonas vaginalis glucose transporter, putative 0.0097 0.0563 0.2929
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0011 0.0019 0.0296
Echinococcus multilocularis tar DNA binding protein 0.007 0.0393 0.0393
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Mycobacterium tuberculosis Probable oxidoreductase 0.0009 0.0006 0.0062
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.007 0.0391 0.6112
Echinococcus multilocularis glycyl tRNA synthetase 0.0018 0.0063 0.0063
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Giardia lamblia Hypothetical protein 0.0009 0.0006 0.0114
Onchocerca volvulus 0.0009 0.0006 0.0038
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0009 0.0006 0.0006
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0014 0.0015
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0011 0.0019 0.029
Echinococcus granulosus glycyl tRNA synthetase 0.0018 0.0063 0.0069
Toxoplasma gondii protein kinase, putative 0.0885 0.5517 1
Echinococcus multilocularis steroid dehydrogenase 0.0009 0.0006 0.0006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0073 0.0808
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.005 0.0779
Trypanosoma cruzi Replication factor A protein 1 0.0009 0.0006 0.0097
Leishmania major glucose transporter, lmgt2 0.0097 0.0563 0.8783
Echinococcus granulosus Aminotransferase class III 0.0022 0.0088 0.0096
Entamoeba histolytica asparaginyl-tRNA synthetase, putative 0.0011 0.0018 0.0328
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0085 0.0155
Loa Loa (eye worm) transcription factor SMAD2 0.0252 0.1534 0.507
Mycobacterium ulcerans sugar transporter 0.0044 0.0229 0.2524
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0299 0.0989
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0009 0.0006 0.0006
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0014 0.0014
Toxoplasma gondii sugar transporter ST3 0.0044 0.0229 0.0415
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0096 0.0558 0.0613
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0044 0.0229 0.2524
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0152 0.0907 1
Schistosoma mansoni hypothetical protein 0.0409 0.252 0.2771
Echinococcus multilocularis Aminotransferase class III 0.0022 0.0088 0.0088
Schistosoma mansoni bromodomain containing protein 0.0009 0.0006 0.0007
Brugia malayi MH1 domain containing protein 0.0017 0.006 0.0198
Echinococcus granulosus Threonyl tRNA synthetase C 0.0018 0.0063 0.0069
Mycobacterium ulcerans hypothetical protein 0.0016 0.005 0.0551
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0038 0.019 0.099
Trypanosoma brucei glucose transporter, putative 0.0097 0.0563 0.8783
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0038 0.019 0.0628
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0009 0.0006 0.0062
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0014 0.0015
Mycobacterium ulcerans short-chain dehydrogenase 0.0009 0.0006 0.0062
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0274 0.0274
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0006 0.0087
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0018 0.0063 0.0693
Echinococcus granulosus FTZ F1 alpha 0.001 0.0014 0.0015
Echinococcus multilocularis dna repair and recombination protein rad54 0.0008 0.0002 0.0002
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0008 0.0002 0.0013
Loa Loa (eye worm) type III restriction enzyme 0.0008 0.0002 0.0007
Giardia lamblia Lysyl-tRNA synthetase 0.007 0.0391 0.7214
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0443 1
Trypanosoma brucei Replication factor A protein 1 0.0009 0.0006 0.0097
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0034 0.0034
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.041 0.6396
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0044 0.0229 0.3573
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.001 0.0012 0.0151
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Echinococcus granulosus microtubule associated protein 2 0.1455 0.9094 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0313 0.1921 0.1921
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0286 0.1748 0.1922
Echinococcus multilocularis synaptic vesicle 2 protein 0.0044 0.0229 0.0229
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Schistosoma mansoni single-minded 0.0146 0.0868 0.0954
Brugia malayi CXXC zinc finger family protein 0.0029 0.0132 0.0438
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0006 0.0097
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0096 0.0558 0.0558
Plasmodium falciparum lysine--tRNA ligase 0.007 0.0391 0.0469
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0014 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0014 0.0046
Echinococcus multilocularis Smad4 0.0017 0.006 0.006
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.005 0.0779
Entamoeba histolytica hypothetical protein 0.0023 0.0099 0.1772
Echinococcus granulosus aryl hydrocarbon receptor 0.0038 0.019 0.0209
Echinococcus granulosus DNA repair and recombination protein RAD54B 0.0008 0.0002 0.0002
Mycobacterium ulcerans aspartyl-tRNA synthetase 0.0011 0.0018 0.0202
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0443 1
Schistosoma mansoni replication factor A 1 rfa1 0.0009 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.055 0.1817
Brugia malayi hypothetical protein 0.0009 0.0006 0.0019
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.001 0.0012 0.0219
Giardia lamblia Threonyl-tRNA synthetase 0.0018 0.0063 0.1157
Mycobacterium ulcerans putative regulatory protein 0.0108 0.063 0.6949
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Echinococcus multilocularis steroid dehydrogenase 0.0009 0.0006 0.0006
Entamoeba histolytica hypothetical protein, conserved 0.0009 0.0006 0.01
Schistosoma mansoni hypothetical protein 0.0033 0.0161 0.0177
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Echinococcus granulosus geminin 0.0357 0.2197 0.2416
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0021
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0096 0.0558 0.0669
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0006 0.0006
Mycobacterium ulcerans oxidoreductase 0.0009 0.0006 0.0062
Schistosoma mansoni hypothetical protein 0.0357 0.2197 0.2416
Schistosoma mansoni DNA ligase IV 0.001 0.0012 0.0013
Trichomonas vaginalis replication factor C large subunit, putative 0.001 0.0012 0.0064
Brugia malayi Dehydrogenases, short chain protein 2 0.0009 0.0006 0.0019
Echinococcus multilocularis solute carrier family 22 0.0044 0.0229 0.0229
Brugia malayi lysyl-tRNA synthetase 0.007 0.0391 0.1294
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0014 0.0014
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0073 0.0381
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0014 0.0046
Onchocerca volvulus 0.0044 0.0229 0.1536
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0044 0.0231 0.36
Giardia lamblia Reductase, putative 0.0009 0.0006 0.0103
Echinococcus granulosus General substrate transporter 0.0269 0.1644 0.1808
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0009 0.0006 0.0006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0014 0.0014
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0059 0.0325 0.3588
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0121 0.2626
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.031 0.4834
Mycobacterium ulcerans bacterioferritin BfrA 0.0009 0.0007 0.0073
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0443 0.4887
Trypanosoma brucei short-chain dehydrogenase, putative 0.0009 0.0006 0.0087
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Plasmodium falciparum calcium-dependent protein kinase 3 0.0096 0.0558 0.0669
Schistosoma mansoni cpg binding protein 0.0029 0.0132 0.0146
Chlamydia trachomatis threonine--tRNA ligase 0.0018 0.0063 0.1417
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0009 0.0006 0.0087
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Leishmania major short chain dehydrogenase-like protein 0.0009 0.0006 0.0087
Echinococcus multilocularis dna polymerase eta 0.0019 0.0073 0.0073
Echinococcus multilocularis geminin 0.0357 0.2197 0.2197
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0073 0.041 0.9238
Giardia lamblia Asparaginyl-tRNA synthetase 0.0011 0.0018 0.0337
Echinococcus multilocularis aryl hydrocarbon receptor 0.0038 0.019 0.019
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0009 0.0006 0.0029
Plasmodium falciparum replication protein A1, large subunit 0.0009 0.0006 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0036 0.0556
Trypanosoma cruzi hexose transporter 0.0097 0.0563 0.8783
Loa Loa (eye worm) hypothetical protein 0.0013 0.0034 0.0112
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Trichomonas vaginalis adenylate cyclase, putative 0.0038 0.019 0.099
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0099 0.1543
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0014 0.0046
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0014 0.0015
Trypanosoma cruzi DNA repair and recombination protein RAD54, putative 0.0008 0.0002 0.0034
Mycobacterium leprae Possible regulatory protein 0.0038 0.019 0.2097
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0018 0.0063 0.098
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0018 0.0063 0.0327
Mycobacterium leprae Probable oxidoreductase 0.0009 0.0006 0.0062
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0018 0.0063 0.0208
Mycobacterium ulcerans dehydrogenase/reductase 0.0009 0.0006 0.0062
Giardia lamblia Hexose transporter 0.0044 0.0229 0.4217
Leishmania major hypothetical protein, conserved 0.0009 0.0006 0.0087
Brugia malayi hypothetical protein 0.0489 0.3025 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.006 0.006
Plasmodium falciparum protein kinase 7 0.0885 0.5517 0.6638
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0073 0.0412 0.0412
Leishmania major hypothetical protein, conserved 0.0009 0.0006 0.0087
Leishmania major DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Schistosoma mansoni hypothetical protein 0.0095 0.055 0.0604
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0073 0.0412 0.4541
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0009 0.0006 0.0029
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Leishmania major short chain dehydrogenase/reductase, putative 0.0009 0.0006 0.0087
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0044 0.0231 0.36
Schistosoma mansoni sugar transporter 0.0044 0.0229 0.0252
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0121 0.0401
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0299 0.0299
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Leishmania major hypothetical protein, conserved 0.0016 0.005 0.0779
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.011 0.0641 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Echinococcus granulosus histone acetyltransferase KAT2B 0.0278 0.1698 0.1867
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0022 0.0088 0.0096
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0094 0.0543 0.0597
Plasmodium vivax asparagine--tRNA ligase, putative 0.0011 0.0018 0.0019
Brugia malayi hypothetical protein 0.001 0.0012 0.004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Leishmania major protein kinase, putative 0.0044 0.0231 0.36
Schistosoma mansoni DNA repair and recombination protein rad54-related 0.0008 0.0002 0.0002
Plasmodium vivax proline--tRNA ligase, putative 0.011 0.0641 0.0768
Leishmania major hypothetical protein, conserved 0.0009 0.0006 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0009 0.0006 0.01
Echinococcus multilocularis replication protein A 70 kDa DNA binding 0.0009 0.0006 0.0006
Schistosoma mansoni DNA polymerase eta 0.0019 0.0073 0.0081
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0073 0.0412 0.4541
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0014 0.0014
Trichomonas vaginalis guanylate cyclase, putative 0.0038 0.019 0.099
Onchocerca volvulus 0.0044 0.0229 0.1536
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0367 0.1212
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.0012 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0558 0.2904
Echinococcus multilocularis carbonyl reductase 1 0.0009 0.0006 0.0006
Schistosoma mansoni glucose transport protein 0.0313 0.1921 0.2112
Trichomonas vaginalis guanylate cyclase, putative 0.0038 0.019 0.099
Echinococcus multilocularis carbonyl reductase 1 0.0009 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0019
Plasmodium falciparum importin beta, putative 0.0029 0.0133 0.0158
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0096 0.0558 0.1012
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0051 0.0051
Schistosoma mansoni sugar transporter 0.0044 0.0229 0.0252
Wolbachia endosymbiont of Brugia malayi aspartyl-tRNA synthetase 0.0011 0.0018 0.029
Schistosoma mansoni ferritin light chain 0.0009 0.0007 0.0007
Trichomonas vaginalis steroid dehydrogenase, putative 0.0009 0.0006 0.0029
Brugia malayi Cam kinase protein 1 0.0096 0.0558 0.1844
Loa Loa (eye worm) oxidoreductase 0.0009 0.0006 0.0019
Schistosoma mansoni carbonyl reductase 0.0009 0.0006 0.0006
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0044 0.0229 0.0273
Trypanosoma brucei unspecified product 0.0013 0.0036 0.0556
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0009 0.0006 0.0032
Schistosoma mansoni lamin 0.0027 0.0121 0.0133
Schistosoma mansoni inositol monophosphatase 0.0073 0.041 0.0451
Entamoeba histolytica DNA repair protein, putative 0.0008 0.0002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0007
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0006 0.0006
Schistosoma mansoni threonyl-tRNA synthetase 0.0011 0.0019 0.002
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0133 0.2078
Leishmania major glycyl tRNA synthetase, putative 0.0011 0.0019 0.029
Loa Loa (eye worm) hypothetical protein 0.0009 0.0012 0.0038
Brugia malayi hypoxia-induced factor 1 0.0451 0.2787 0.9213
Loa Loa (eye worm) inositol-1 0.0073 0.041 0.1354
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0014 0.0014
Echinococcus granulosus hypothetical protein 0.0009 0.0006 0.0006
Brugia malayi Bromodomain containing protein 0.0009 0.0006 0.0021
Onchocerca volvulus 0.0044 0.0229 0.1536
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0073 0.1143
Giardia lamblia DINP protein human, muc B family 0.0019 0.0073 0.1349
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0088 0.0968
Trichomonas vaginalis ferritin, putative 0.0009 0.0007 0.0034
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0016 0.005 0.009
Loa Loa (eye worm) major facilitator superfamily transporter 0.0044 0.0229 0.0757
Echinococcus multilocularis GPCR, family 2 0.0033 0.0161 0.0161
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0014 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Mycobacterium ulcerans hypothetical protein 0.0152 0.0907 1
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0014 0.0015
Plasmodium vivax replication protein A1, large subunit, putative 0.0009 0.0006 0.0005
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0367 0.5722
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0008 0.0002 0.0007
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0011 0.0018 0.002
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0064
Brugia malayi MH2 domain containing protein 0.0017 0.006 0.0198
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.005 0.0779
Onchocerca volvulus 0.0044 0.0229 0.1536
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0022 0.0088 0.0968
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Echinococcus granulosus retinol dehydrogenase 11 0.0009 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0046
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0443 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0367 0.5722
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0009 0.0006 0.0087
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0073 0.0081
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0009 0.0006 0.0087
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0014 0.0046
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0014 0.0015
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Schistosoma mansoni peptidase 0.001 0.0013 0.0015
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0161 0.0177
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0051 0.08
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0073 0.0073
Brugia malayi Smad1 0.0017 0.006 0.0198
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0008 0.0009
Brugia malayi major facilitator superfamily protein 0.0044 0.0229 0.0757
Schistosoma mansoni protein kinase 0.0096 0.0558 0.0613
Trypanosoma brucei glucose transporter, putative 0.0097 0.0563 0.8783
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0011 0.0019 0.0061
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0009 0.0006 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0022 0.0088 0.198
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0006 0.0087
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0009 0.0006 0.0087
Plasmodium falciparum calcium-dependent protein kinase 4 0.0096 0.0558 0.0669
Plasmodium vivax calcium-dependent protein kinase, putative 0.0096 0.0558 0.0669
Schistosoma mansoni histidyl-tRNA synthetase 0.0011 0.0019 0.002
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0034 0.0037
Trypanosoma brucei DNA repair and recombination protein RAD54, putative 0.0008 0.0002 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Onchocerca volvulus 0.0049 0.0263 0.1763
Loa Loa (eye worm) 63kd antigen 0.0011 0.0018 0.006
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0009 0.0006 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0313 0.1921 1
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0006 0.0006
Schistosoma mansoni ran 0.0021 0.0085 0.0094
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0009 0.0006 0.0004
Trypanosoma cruzi FHA domain containing protein, putative 0.001 0.0012 0.0191
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Loa Loa (eye worm) oxidoreductase 0.0009 0.0006 0.0019
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0009 0.0006 0.0087
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0051 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.031 0.034
Leishmania major dehydrogenase-like protein 0.0009 0.0006 0.0087
Trypanosoma cruzi hexose transporter, putative 0.0097 0.0563 0.8783
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0051 0.0565
Schistosoma mansoni cpg binding protein 0.003 0.0143 0.0157
Brugia malayi bHLH-PAS transcription factor 0.0108 0.063 0.2082
Leishmania major pteridine reductase 1 0.0009 0.0006 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.005 0.026
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0099 0.0515
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0022 0.0088 0.029
Loa Loa (eye worm) hypothetical protein 0.0026 0.0118 0.0391
Trichomonas vaginalis sugar transporter, putative 0.0097 0.0563 0.2929
Echinococcus granulosus smad 0.0017 0.006 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.019 0.099
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0088 0.0088
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Schistosoma mansoni thyroid hormone receptor 0.001 0.0014 0.0015
Echinococcus granulosus solute carrier family 22 0.0044 0.0229 0.0252
Brugia malayi nuclear receptor NHR-88 0.001 0.0014 0.0046
Brugia malayi oxidoreductase 0.0009 0.0006 0.0019
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0038 0.019 0.019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0014 0.0046
Loa Loa (eye worm) hypothetical protein 0.007 0.0391 0.1294
Loa Loa (eye worm) oxidoreductase 0.0009 0.0006 0.0019
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0073 0.0412 0.4541
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0009 0.0006 0.0103
Entamoeba histolytica Ran family GTPase 0.0021 0.0085 0.1529
Leishmania major threonyl-tRNA synthetase, putative 0.0018 0.0063 0.098
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0046
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0006 0.0087
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0096 0.0558 0.1012
Trypanosoma brucei short-chain dehydrogenase, putative 0.0009 0.0006 0.0087
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.0009 0.0006 0.0042
Echinococcus granulosus lysyl tRNA synthetase 0.007 0.0391 0.043
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0009 0.0006 0.0029
Mycobacterium ulcerans short-chain dehydrogenase 0.0009 0.0006 0.0062
Brugia malayi Inositol-1 0.0073 0.041 0.1354
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Echinococcus granulosus SPRY domain containing protein 0.0008 0.0002 0.0002
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0043 0.0141
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0096 0.0558 0.0669
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0313 0.1921 0.2112
Onchocerca volvulus 0.0009 0.0006 0.0038
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0011 0.0019 0.0333
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0099 0.0515
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.005 0.0551
Loa Loa (eye worm) hypothetical protein 0.0466 0.2882 0.9528
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0335 0.0368
Loa Loa (eye worm) hypoxia-induced factor 1 0.0451 0.2787 0.9213
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0009 0.0006 0.0097
Echinococcus multilocularis histidyl tRNA synthetase 0.0011 0.0019 0.0019
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0084 0.048 0.087
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.001 0.0012 0.004
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0073 0.1143
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0014 0.0046
Mycobacterium tuberculosis Probable oxidoreductase 0.0009 0.0006 0.0062
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Mycobacterium tuberculosis Probable dehydrogenase 0.0009 0.0006 0.0062
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0121 0.0401
Entamoeba histolytica hypothetical protein 0.007 0.0391 0.7018
Entamoeba histolytica hypothetical protein 0.0009 0.0006 0.0111
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Schistosoma mansoni coup transcription factor 0.001 0.0014 0.0015
Onchocerca volvulus 0.0029 0.0132 0.0889
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0073 0.0242
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0061 0.0337 0.1756
Trypanosoma cruzi glucose transporter, putative 0.0044 0.0229 0.3573
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0009 0.0006 0.0006
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0443 0.0531
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0073 0.1143
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Toxoplasma gondii hypothetical protein 0.0027 0.0121 0.022
Schistosoma mansoni ferritin 0.0009 0.0007 0.0007
Schistosoma mansoni tar DNA-binding protein 0.007 0.0393 0.0433
Plasmodium falciparum ornithine aminotransferase 0.0022 0.0088 0.0103
Brugia malayi Major Facilitator Superfamily protein 0.0044 0.0229 0.0757
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0009 0.0006 0.0062
Echinococcus granulosus neuropeptide s receptor 0.0467 0.2884 0.3172
Mycobacterium ulcerans carveol-like dehydrogenase 0.0009 0.0006 0.0062
Leishmania major hypothetical protein, conserved 0.0009 0.0006 0.0087
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Toxoplasma gondii facilitative glucose transporter GT1 0.0313 0.1921 0.3481
Schistosoma mansoni hypothetical protein 0.0072 0.0403 0.0444
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0313 0.1921 0.2112
Echinococcus multilocularis survival motor neuron protein 1 0.0466 0.2882 0.2882
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0507 0.3136 0.5684
Trypanosoma cruzi DNA repair and recombination protein RAD54, putative 0.0008 0.0002 0.0034
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0039 0.0194 0.0643
Schistosoma mansoni topbp1 0.001 0.0012 0.0013
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0011 0.0019 0.0097
Echinococcus multilocularis zinc finger protein 0.0009 0.0006 0.0006
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0044 0.0229 0.2524
Onchocerca volvulus Huntingtin homolog 0.0245 0.149 1
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Echinococcus multilocularis lamin 0.0027 0.0121 0.0121
Echinococcus multilocularis conserved hypothetical protein 0.0009 0.0006 0.0006
Plasmodium vivax steroid dehydrogenase, putative 0.0009 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.004
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0263 0.0289
Echinococcus multilocularis ferritin 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0046
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0022 0.0088 0.1878
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0085 0.01
Onchocerca volvulus 0.0009 0.0006 0.0038
Brugia malayi MH1 domain containing protein 0.0009 0.0012 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0097 0.0563 0.2929
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0009 0.0006 0.0062
Trichomonas vaginalis glucose transporter, putative 0.0044 0.0229 0.1191
Plasmodium vivax replication factor C subunit 1, putative 0.001 0.0012 0.0012
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0121 0.0401
Loa Loa (eye worm) MH2 domain-containing protein 0.0252 0.1534 0.507
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0229 0.1191
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Mycobacterium tuberculosis Possible oxidoreductase 0.0009 0.0006 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0009 0.0006 0.0087
Echinococcus granulosus histone acetyltransferase KAT2B 0.0084 0.048 0.0528
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0022 0.0088 0.0968
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0009 0.0006 0.0087
Toxoplasma gondii anticodon binding domain-containing protein 0.0011 0.0019 0.0034
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0018 0.002
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0009 0.0006 0.0004
Trypanosoma brucei THT1 - hexose transporter, putative 0.0097 0.0563 0.8783
Schistosoma mansoni zinc finger protein 0.0009 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0009 0.0006 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0014 0.0046
Loa Loa (eye worm) sugar transporter 0.0044 0.0229 0.0757
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0085 0.1331
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.006 0.0066
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0009 0.0006 0.0032
Schistosoma mansoni sugar transporter 0.0044 0.0229 0.0252
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0078 0.0443 0.4887
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0009 0.0006 0.0062
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0367 0.5722
Schistosoma mansoni protein kinase 0.0096 0.0558 0.0613
Echinococcus multilocularis solute carrier family 22 0.0044 0.0229 0.0229
Trichomonas vaginalis myo-inositol transporter, putative 0.0044 0.0229 0.1191
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0398 0.0437
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0036 0.0556
Brugia malayi Pax transcription activation domain interacting protein 0.001 0.0012 0.004
Entamoeba histolytica protein kinase, putative 0.0096 0.0558 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0078 0.0443 0.0487
Toxoplasma gondii OB-fold nucleic acid binding domain-containing protein 0.0009 0.0006 0.0011
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0443 0.4887
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0313 0.1921 0.1921
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0073 0.1313
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0014 0.0046
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0014 0.0046
Echinococcus multilocularis inositol monophosphatase 1 0.0073 0.041 0.041
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0014 0.0015
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0085 0.1572
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0014 0.0014
Onchocerca volvulus Huntingtin homolog 0.0245 0.149 1
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0009 0.0006 0.0062
Schistosoma mansoni carbonyl reductase 0.0009 0.0006 0.0006
Leishmania major GTP-binding protein, putative 0.0021 0.0085 0.1331
Echinococcus multilocularis dnaJ subfamily B 0.0409 0.252 0.252
Entamoeba histolytica short chain dehydrogenase family protein 0.0009 0.0006 0.01
Onchocerca volvulus 0.0009 0.0006 0.0038
Loa Loa (eye worm) replication factor A 73 kDa subunit 0.0009 0.0006 0.0021
Echinococcus multilocularis calcium dependent protein kinase 0.009 0.0518 0.0518
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0006 0.0087
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0059 0.0325 0.3588
Entamoeba histolytica hypothetical protein 0.0071 0.0398 0.7133
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Leishmania major protein kinase, putative 0.0096 0.0558 0.8708
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0014 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0014 0.0046
Echinococcus granulosus dna polymerase eta 0.0019 0.0073 0.0081
Mycobacterium ulcerans oxidoreductase 0.0009 0.0006 0.0062
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0019
Giardia lamblia Aspartyl-tRNA synthetase 0.0011 0.0018 0.0337
Echinococcus multilocularis solute carrier family 22 0.0044 0.0229 0.0229
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0096 0.0558 0.0613
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0051 0.0169
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0014 0.0014
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0009 0.0006 0.0087
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0299 0.0329
Onchocerca volvulus 0.0095 0.055 0.369
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Brugia malayi hypothetical protein 0.0071 0.0398 0.1315
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.041 0.2133
Loa Loa (eye worm) dehydrogenase 0.0009 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0013 0.0031 0.0101
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0033 0.0161 0.1772
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0398 0.0398
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0084 0.048 0.25
Echinococcus multilocularis neuropeptide receptor A26 0.0467 0.2884 0.2884
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0299 0.0329
Leishmania major replication Factor A 28 kDa subunit, putative 0.0009 0.0006 0.0097
Brugia malayi Sugar transporter family protein 0.0044 0.0229 0.0757
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0051 0.08
Loa Loa (eye worm) oxidoreductase 0.0009 0.0006 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.005 0.026
Plasmodium falciparum proline--tRNA ligase 0.011 0.0641 0.0768
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0009 0.0006 0.0062
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0009 0.0006 0.01
Plasmodium falciparum protein kinase 6 0.133 0.8311 1
Schistosoma mansoni hypothetical protein 0.0308 0.1885 0.2073
Schistosoma mansoni thyroid hormone receptor 0.001 0.0014 0.0015
Echinococcus granulosus intermediate filament protein 0.0027 0.0121 0.0133
Brugia malayi hypothetical protein 0.001 0.0012 0.004
Giardia lamblia Hypothetical protein 0.0009 0.0006 0.0103
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0558 0.0613
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0008 0.0002 0.0013
Echinococcus granulosus oxidoreductase 0.0009 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0014 0.0046
Echinococcus multilocularis musashi 0.0027 0.0121 0.0121
Schistosoma mansoni tar DNA-binding protein 0.007 0.0393 0.0433
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0009 0.0006 0.0087
Plasmodium falciparum aspartate--tRNA ligase 0.0011 0.0018 0.0019
Mycobacterium tuberculosis Probable aminotransferase 0.0152 0.0907 1
Mycobacterium ulcerans short-chain dehydrogenase 0.0009 0.0006 0.0062
Onchocerca volvulus 0.0009 0.0006 0.0038
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0038 0.019 0.099
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0358 0.1184
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0367 0.0403
Schistosoma mansoni aryl hydrocarbon receptor 0.0146 0.0868 0.0954
Trypanosoma brucei histidyl-tRNA synthetase 0.0011 0.0019 0.029
Toxoplasma gondii sugar transporter ST1 0.0044 0.0229 0.0415
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0051 0.0059
Onchocerca volvulus 0.0027 0.0121 0.0815
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0018 0.0063 0.1126
Echinococcus multilocularis 0.0008 0.0002 0.0002
Brugia malayi hypothetical protein 0.0044 0.0229 0.0757
Schistosoma mansoni ferritin 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0019
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0009 0.0006 0.0029
Echinococcus multilocularis General substrate transporter 0.0269 0.1644 0.1644
Schistosoma mansoni glucose transport protein 0.0313 0.1921 0.2112
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0009 0.0007 0.0073
Mycobacterium tuberculosis Probable oxidoreductase 0.0009 0.0006 0.0062
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0014 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Echinococcus granulosus GPCR family 2 0.0033 0.0161 0.0177
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0014 0.0014
Toxoplasma gondii transporter, major facilitator family protein 0.0044 0.0229 0.0415
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0073 0.0081
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0006 0.0087
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0009 0.0006 0.0038
Leishmania major DNA repair and recombination protein RAD54, putative 0.0008 0.0002 0.0034
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Mycobacterium leprae conserved hypothetical protein 0.0016 0.005 0.0551
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0012 0.0064
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0009 0.0006 0.0007
Giardia lamblia Short-chain dehydrogenase, putative 0.0009 0.0006 0.0103
Chlamydia trachomatis histidine--tRNA ligase 0.0011 0.0019 0.0419
Echinococcus granulosus solute carrier family 22 0.0044 0.0229 0.0252
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.041 0.6396
Echinococcus granulosus Sugar transporter ERD6 protein 0.0044 0.0229 0.0252
Echinococcus granulosus lamin dm0 0.0027 0.0121 0.0133
Trichomonas vaginalis sugar transport protein, putative 0.0044 0.0229 0.1191
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0009 0.0007 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0012 0.0191
Echinococcus granulosus carbonyl reductase 1 0.0009 0.0006 0.0006
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.031 0.5705
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0009 0.0006 0.0062
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.041 0.6396
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0085 0.0282
Leishmania major replication factor A, 51kDa subunit, putative 0.0009 0.0006 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0014 0.0046
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0014 0.0015
Loa Loa (eye worm) dehydrogenase 0.0009 0.0006 0.0019
Plasmodium vivax CDK-related protein kinase 6, putative 0.133 0.8311 1
Echinococcus multilocularis aspartyl tRNA synthetase, cytoplasmic 0.0011 0.0018 0.0018
Trypanosoma brucei glucose transporter, putative 0.0097 0.0563 0.8783
Mycobacterium leprae PROBABLE DNA POLYMERASE III (ALPHA CHAIN) DNAE1 (DNA NUCLEOTIDYLTRANSFERASE) 0.0009 0.0006 0.0068
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0051 0.0051
Trypanosoma cruzi hexose transporter, putative 0.0044 0.0229 0.3573
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0038 0.019 0.0209
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Trypanosoma brucei unspecified product 0.0019 0.0073 0.1143
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0 0.0001
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0009 0.0006 0.0087
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0044 0.0229 0.0229
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0096 0.0558 0.0613
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0022 0.0088 0.0968
Echinococcus multilocularis cpg binding protein 0.003 0.0143 0.0143
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Schistosoma mansoni Smad4 0.0017 0.006 0.0066
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0018 0.0063 0.0693
Plasmodium falciparum nucleic acid binding protein, putative 0.0009 0.0006 0.0005
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.001
Brugia malayi PAS domain containing protein 0.0146 0.0868 0.2869
Onchocerca volvulus 0.0009 0.0006 0.0038
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0006 0.0006
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.006 0.006
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0009 0.0006 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Schistosoma mansoni apoferritin-2 0.0009 0.0007 0.0007
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0018 0.002
Schistosoma mansoni hypothetical protein 0.0033 0.0161 0.0177
Echinococcus granulosus carbonyl reductase 1 0.0009 0.0006 0.0006
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0009 0.0006 0.001
Trypanosoma brucei protein kinase, putative 0.0057 0.031 0.4834
Plasmodium vivax histidine--tRNA ligase, putative 0.0011 0.0019 0.002
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0008 0.0008
Echinococcus multilocularis solute carrier family 22 0.0044 0.0229 0.0229
Trypanosoma brucei THT1 - hexose transporter, putative 0.0097 0.0563 0.8783
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.004
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0018 0.0063 0.0208
Echinococcus granulosus solute carrier family 22 0.0044 0.0229 0.0252
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0073 0.0808
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0299 0.0329
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.031 0.1612
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0051 0.0093
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.001
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0073 0.041 0.452
Echinococcus granulosus tar DNA binding protein 0.007 0.0393 0.0433
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Loa Loa (eye worm) hypothetical protein 0.0245 0.149 0.4924
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0299 0.0299
Schistosoma mansoni ferritin 0.0009 0.0007 0.0007
Schistosoma mansoni lysyl-tRNA synthetase 0.007 0.0391 0.043
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0094 0.0543 0.2825
Schistosoma mansoni topbp1 0.001 0.0012 0.0013
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0132 0.0438
Trypanosoma cruzi hexose transporter, putative 0.0097 0.0563 0.8783
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0161 0.0177
Trypanosoma brucei asparaginyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Loa Loa (eye worm) oxidoreductase 0.0009 0.0006 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.019 0.099
Giardia lamblia Histone acetyltransferase GCN5 0.0077 0.0436 0.8038
Brugia malayi hypothetical protein 0.0466 0.2882 0.9528
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.011 0.0641 1
Brugia malayi steroid hormone receptor 0.001 0.0014 0.0046
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.031 0.034
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Entamoeba histolytica hypothetical protein, conserved 0.0009 0.0006 0.01
Loa Loa (eye worm) hypothetical protein 0.0049 0.0263 0.0868
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0313 0.1921 0.2112
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0009 0.0006 0.001
Brugia malayi dehydrogenases, short chain protein 9 0.0009 0.0006 0.0019
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Trichomonas vaginalis glucose transporter, putative 0.0097 0.0563 0.2929
Echinococcus granulosus carbonyl reductase 1 0.0009 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0019
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0152 0.0907 0.472
Toxoplasma gondii carbonyl reductase 1, putative 0.0009 0.0006 0.001
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.031 0.031
Onchocerca volvulus 0.0044 0.0229 0.1536
Brugia malayi Retinol dehydrogenase 12 0.0009 0.0006 0.0019
Schistosoma mansoni cpg binding protein 0.003 0.0143 0.0157
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0096 0.0558 0.8708
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0012 0.0064
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0044 0.0229 0.2524
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0009 0.0006 0.0062
Plasmodium vivax hexose transporter 0.0313 0.1921 0.2309
Entamoeba histolytica hypothetical protein 0.0071 0.0398 0.7133
Onchocerca volvulus 0.0044 0.0229 0.1536
Loa Loa (eye worm) acetyltransferase 0.0286 0.1748 0.5778
Mycobacterium tuberculosis Probable oxidoreductase 0.0009 0.0006 0.0062
Loa Loa (eye worm) oxidoreductase 0.0009 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.004
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0009 0.0006 0.0029
Schistosoma mansoni aspartyl-tRNA synthetase 0.0009 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0046
Leishmania major aspartyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Brugia malayi Importin beta-1 subunit 0.0029 0.0133 0.044
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0367 0.5722
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0084 0.048 0.0575
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0038 0.019 0.099
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0063 0.098
Loa Loa (eye worm) Smad1 0.0017 0.006 0.0198
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0019
Onchocerca volvulus 0.0044 0.0229 0.1536
Leishmania major myo-inositol/proton symporter (MIT) 0.0044 0.0229 0.3573
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0094 0.0543 0.0597
Mycobacterium ulcerans ketoacyl reductase 0.0009 0.0006 0.0062
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0094 0.0543 0.0597
Loa Loa (eye worm) hypothetical protein 0.0072 0.0403 0.1334
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0009 0.0006 0.0038
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0014 0.0046
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.001 0.0012 0.0135
Plasmodium falciparum threonine--tRNA ligase 0.0018 0.0063 0.0073
Mycobacterium ulcerans dehydrogenase 0.0009 0.0006 0.0062
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0019
Onchocerca volvulus 0.0009 0.0006 0.0038
Echinococcus granulosus dnaJ subfamily B 0.0409 0.252 0.2771
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0308 0.1885 0.6231
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0009 0.0006 0.01
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0274 0.3021
Mycobacterium ulcerans bacterioferritin BfrB 0.0009 0.0007 0.0073
Trypanosoma cruzi short chain dehydrogenase, putative 0.0009 0.0006 0.0087
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.031 0.031
Leishmania major DNA polymerase eta, putative 0.0019 0.0073 0.1143
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0299 0.0989
Schistosoma mansoni survival motor neuron protein 0.0095 0.055 0.0604
Loa Loa (eye worm) hypothetical protein 0.0018 0.0063 0.0208
Brugia malayi RNA, U transporter 1 0.0082 0.0467 0.1543
Echinococcus multilocularis SPRY domain containing protein 0.0008 0.0002 0.0002
Echinococcus granulosus hypothetical protein 0.0009 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Echinococcus multilocularis retinol dehydrogenase 11 0.0009 0.0006 0.0006
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.007 0.0391 0.4318
Brugia malayi MH1 domain containing protein 0.0009 0.0012 0.0038
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0018 0.0063 0.0693
Loa Loa (eye worm) sugar transporter 0.0313 0.1921 0.635
Brugia malayi hypothetical protein 0.0044 0.0229 0.0757
Schistosoma mansoni hypothetical protein 0.0033 0.0161 0.0177
Brugia malayi Major Facilitator Superfamily protein 0.0044 0.0229 0.0757
Brugia malayi DKFZp564C0469 protein 0.001 0.0012 0.004
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0009 0.0006 0.0005
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0161 0.0161
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0073 0.0808
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0051 0.0169
Trypanosoma brucei THT1 - hexose transporter, putative 0.0097 0.0563 0.8783
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0018 0.0063 0.098
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0018 0.002
Brugia malayi MH1 domain containing protein 0.0017 0.006 0.0198
Onchocerca volvulus Putative transporter 0.0044 0.0229 0.1536
Trichomonas vaginalis sugar transporter, putative 0.0097 0.0563 0.2929
Brugia malayi nuclear hormone receptor 0.001 0.0014 0.0046
Echinococcus multilocularis tumor protein p63 0.0338 0.2074 0.2074
Onchocerca volvulus 0.0009 0.0006 0.0038
Entamoeba histolytica short chain dehydrogenase family protein 0.0009 0.0006 0.01
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0012 0.0064
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0009 0.0006 0.0062
Plasmodium falciparum hexose transporter 0.0313 0.1921 0.2309
Entamoeba histolytica hypothetical protein 0.0071 0.0398 0.7133
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0006 0.0087
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0274 0.3021
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0019
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Echinococcus granulosus single minded 2 0.0108 0.063 0.0693
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0044 0.0231 0.36
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0073 0.1143
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0009 0.0006 0.0006
Echinococcus multilocularis dna repair and recombination protein rad54 0.0008 0.0002 0.0002
Brugia malayi hypothetical protein 0.0245 0.149 0.4924
Schistosoma mansoni ferritin 0.0009 0.0007 0.0007
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) 0.0009 0.0006 0.0068
Loa Loa (eye worm) hypothetical protein 0.0027 0.0121 0.0401
Entamoeba histolytica DNA repair protein, putative 0.0008 0.0002 0.0039
Schistosoma mansoni protein kinase 0.0096 0.0558 0.0613
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Loa Loa (eye worm) aspartyl-tRNA synthetase 0.0011 0.0018 0.006
Chlamydia trachomatis lysine--tRNA ligase 0.007 0.0391 0.8836
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0051 0.08
Echinococcus multilocularis dna repair and recombination protein rad54 0.0008 0.0002 0.0002
Brugia malayi hypothetical protein 0.0044 0.0229 0.0757
Schistosoma mansoni glucose transport protein 0.0313 0.1921 0.2112
Plasmodium vivax asparagine--tRNA ligase, putative 0.0011 0.0018 0.0019
Trypanosoma brucei short-chain dehydrogenase, putative 0.0009 0.0006 0.0087
Echinococcus granulosus nibrin 0.001 0.0012 0.0013
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0051 0.0056
Plasmodium falciparum mitogen-activated protein kinase 2 0.0507 0.3136 0.3772
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0009 0.0006 0.0019
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0313 0.1921 0.1921
Onchocerca volvulus 0.0044 0.0229 0.1536
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0152 0.0907 1
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0022 0.0088 0.0968
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0161 0.0161
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0073 0.0412 0.0453
Echinococcus multilocularis 0.0008 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0014 0.0046
Echinococcus granulosus WW domain containing oxidoreductase 0.0009 0.0006 0.0006
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Echinococcus granulosus cpg binding protein 0.003 0.0143 0.0157
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0096 0.0558 0.1012
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0161 0.0532
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0152 0.0907 1
Schistosoma mansoni hypothetical protein 0.0071 0.0398 0.0437
Onchocerca volvulus 0.0009 0.0006 0.0038
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0022 0.0088 0.0968
Echinococcus multilocularis carbonyl reductase 1 0.0009 0.0006 0.0006
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Trypanosoma brucei glucose transporter, putative 0.0097 0.0563 0.8783
Trichomonas vaginalis ran, putative 0.0021 0.0085 0.0444
Echinococcus granulosus retinol dehydrogenase 11 0.0009 0.0006 0.0006
Brugia malayi PHD-finger family protein 0.0009 0.0006 0.0021
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Leishmania major hypothetical protein, conserved 0.0009 0.0006 0.0087
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0018 0.0063 0.0114
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0009 0.0006 0.0062
Trypanosoma brucei unspecified product 0.0013 0.0036 0.0556
Plasmodium falciparum replication factor C subunit 1, putative 0.001 0.0012 0.0012
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0085 0.1331
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0338 0.0612
Plasmodium falciparum asparagine--tRNA ligase 0.0011 0.0018 0.0019
Brugia malayi Calcitonin receptor-like protein seb-1 0.0105 0.0612 0.2025
Loa Loa (eye worm) hypothetical protein 0.0078 0.0443 0.1465
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.011 0.0641 1
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) 0.0009 0.0006 0.0068
Echinococcus granulosus synaptic vesicle 2 protein 0.0044 0.0229 0.0252
Brugia malayi Sugar transporter family protein 0.0044 0.0229 0.0757
Plasmodium vivax glycine--tRNA ligase, putative 0.0018 0.0063 0.0073
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0078 0.0443 0.0443
Trypanosoma brucei glucose transporter 2A 0.0097 0.0563 0.8783
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0006 0.0006
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0051 0.0059
Brugia malayi Aspartyl-tRNA synthetase 0.0011 0.0018 0.006
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0018 0.0063 0.1307
Brugia malayi replication factor A 73 kDa subunit 0.0009 0.0006 0.0021
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Echinococcus granulosus snurportin 1 0.0308 0.1885 0.2073
Schistosoma mansoni histidyl-tRNA synthetase 0.0011 0.0019 0.002
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0009 0.0006 0.0087
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0121 0.0143
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.001
Plasmodium falciparum asparagine--tRNA ligase 0.0011 0.0018 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0006 0.0087
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0007
Onchocerca volvulus 0.0108 0.063 0.4229
Trypanosoma brucei glucose transporter, putative 0.0097 0.0563 0.8783
Onchocerca volvulus 0.0009 0.0006 0.0038
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.031 0.4834
Echinococcus multilocularis retinol dehydrogenase 11 0.0009 0.0006 0.0006
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.006 0.0198
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0 0.0001
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0286 0.1748 0.1748
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0046
Leishmania major short chain dehydrogenase, putative 0.0009 0.0006 0.0087
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0192 0.0211
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.004
Trypanosoma brucei oxidoreductase-like protein 0.0009 0.0006 0.0087
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.041 0.2133
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0064
Treponema pallidum threonyl-tRNA synthetase 0.0018 0.0063 0.1287
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Leishmania major lysyl-tRNA synthetase, putative 0.007 0.0391 0.6112
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0012 0.0191
Echinococcus granulosus ornithine aminotransferase 0.0022 0.0088 0.0096
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.005 0.0779
Mycobacterium tuberculosis Probable oxidoreductase 0.0009 0.0006 0.0062
Mycobacterium ulcerans lysyl-tRNA synthetase 0.007 0.0391 0.4318
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0073 0.0412 0.1361
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0009 0.0006 0.0062
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0009 0.0006 0.0087
Onchocerca volvulus 0.0044 0.0229 0.1536
Echinococcus granulosus replication protein A 70 kDa DNA binding 0.0009 0.0006 0.0007
Plasmodium vivax sugar transporter, putative 0.0044 0.0229 0.0273
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0046
Echinococcus granulosus importin subunit beta 1 0.0029 0.0133 0.0146
Mycobacterium ulcerans ketoacyl reductase 0.0009 0.0006 0.0062
Leishmania major short chain dehydrogenase, putative 0.0009 0.0006 0.0087
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0012 0.0027 0.0419
Giardia lamblia Replication factor C, subunit 1 0.001 0.0012 0.0225
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Brugia malayi mothers against decapentaplegic homolog 3 0.0008 0 0.0001
Toxoplasma gondii ATPase, AAA family protein 0.001 0.0012 0.0022
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0009 0.0007 0.0073
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0105 0.0612 0.2025
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0018 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Plasmodium vivax aspartate--tRNA ligase, putative 0.0011 0.0018 0.0019
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0393 0.1301
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.031 0.1612
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.031 0.1612
Echinococcus multilocularis oxidoreductase 0.0009 0.0006 0.0006
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0313 0.1921 0.2112
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Plasmodium vivax ornithine aminotransferase, putative 0.0022 0.0088 0.0103
Echinococcus multilocularis carbonyl reductase 1 0.0009 0.0006 0.0006
Leishmania major protein kinase, putative 0.0044 0.0231 0.36
Brugia malayi Dehydrogenases, short chain protein 30 0.0009 0.0006 0.0019
Loa Loa (eye worm) oxidoreductase 0.0009 0.0006 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0073 0.0381
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.004
Echinococcus granulosus survival motor neuron protein 1 0.0466 0.2882 0.3169
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0009 0.0006 0.0006
Mycobacterium ulcerans short-chain type oxidoreductase 0.0009 0.0006 0.0062
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.031 0.4834
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0064
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0009 0.0006 0.0019
Chlamydia trachomatis aspartate--tRNA(Asp/Asn) ligase 0.0011 0.0018 0.0412
Treponema pallidum DNA ligase (lig) 0.001 0.0012 0.0128
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0105 0.0612 0.2025
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0009 0.0006 0.01
Brugia malayi Asparaginyl-tRNA synthetase, cytoplasmic 0.0011 0.0018 0.006
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0009 0.0006 0.01
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0065 0.0362 0.399
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0018 0.002
Toxoplasma gondii oxidoreductase, putative 0.0009 0.0006 0.001
Entamoeba histolytica protein kinase, putative 0.0096 0.0558 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0014 0.0046
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0043 0.0141
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0014 0.0093
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0019
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0018 0.002
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0096 0.0558 0.0558
Plasmodium falciparum calcium-dependent protein kinase 5 0.0096 0.0558 0.0669
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0012 0.0191
Trypanosoma cruzi hexose transporter, putative 0.0053 0.0286 0.4462
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0096 0.0558 0.0558
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0009 0.0006 0.0006
Mycobacterium ulcerans L-lysine aminotransferase 0.0022 0.0088 0.0968
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0011 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0357 0.2197 0.2416
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0078 0.0443 1
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0121 0.1337
Echinococcus granulosus tumor protein p63 0.0338 0.2074 0.228
Schistosoma mansoni glycyl-tRNA synthetase 0.0018 0.0063 0.0069
Leishmania major aspartyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Entamoeba histolytica hypothetical protein 0.0009 0.0006 0.01
Echinococcus multilocularis microtubule associated protein 2 0.1455 0.9094 0.9094
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0313 0.1921 0.2112
Schistosoma mansoni importin beta-1 0.0029 0.0133 0.0146
Toxoplasma gondii lysine-tRNA ligase 0.007 0.0391 0.071
Schistosoma mansoni smad 0.0017 0.006 0.0066
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0051 0.0051
Echinococcus granulosus calcium dependent protein kinase 0.009 0.0518 0.0569
Schistosoma mansoni bromodomain containing protein 0.0009 0.0006 0.0007
Onchocerca volvulus 0.0027 0.0121 0.0815
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0192 0.0192
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0063 0.098
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0051 0.0093
Schistosoma mansoni hypothetical protein 0.0009 0.0006 0.0007
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0299 0.0329
Schistosoma mansoni lamin 0.0027 0.0121 0.0133
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0073 0.0081
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0006 0.0087
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0161 0.0532
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0021
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0051 0.08
Trypanosoma brucei glucose transporter, putative 0.0097 0.0563 0.8783
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0014 0.0015
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0014 0.0014
Onchocerca volvulus 0.001 0.0012 0.0082
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0009 0.0006 0.0062
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0022 0.0088 0.0159
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0274 0.3021
Entamoeba histolytica hypothetical protein 0.001 0.0012 0.0219
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Loa Loa (eye worm) major facilitator superfamily transporter 0.0044 0.0229 0.0757
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0096 0.0558 0.0669
Trypanosoma cruzi hexose transporter, putative 0.0097 0.0563 0.8783
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0014 0.0046
Schistosoma mansoni ran 0.0021 0.0085 0.0094
Chlamydia trachomatis proline--tRNA ligase 0.0033 0.0161 0.3626
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0161 0.0532
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Schistosoma mansoni apoferritin-2 0.0009 0.0007 0.0007
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0133 0.0133
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.006 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0014 0.0046
Onchocerca volvulus 0.0044 0.0229 0.1536
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0078 0.0443 0.0531
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0064
Plasmodium falciparum calcium-dependent protein kinase 2 0.0096 0.0558 0.0669
Loa Loa (eye worm) hypothetical protein 0.0096 0.0558 0.1844
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0403 0.1334
Entamoeba histolytica hypothetical protein 0.0071 0.0398 0.7133
Echinococcus multilocularis lamin dm0 0.0027 0.0121 0.0121
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0036 0.0556
Echinococcus granulosus SPRY domain containing protein 0.0008 0.0002 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Loa Loa (eye worm) hypothetical protein 0.0076 0.0432 0.1428
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0367 0.6571
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0044 0.0229 0.2524
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0009 0.0006 0.0029
Trypanosoma cruzi asparaginyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Brugia malayi MH2 domain containing protein 0.0252 0.1534 0.507
Entamoeba histolytica acetyltransferase, GNAT family 0.0077 0.0436 0.782
Schistosoma mansoni carbonyl reductase 0.0009 0.0006 0.0006
Echinococcus multilocularis lysyl tRNA synthetase 0.007 0.0391 0.0391
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0073 0.0242
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.031 0.4834
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0022 0.0088 0.0968
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0073 0.1143
Leishmania major lysyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0133 0.2078
Onchocerca volvulus 0.0044 0.0229 0.1536
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0229 0.1191
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0006 0.0087
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0073 0.041 0.0743
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.031 0.034
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0006 0.0006
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0059 0.0325 0.3588
Schistosoma mansoni tar DNA-binding protein 0.007 0.0393 0.0433
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0007 0.0024
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0038 0.019 0.099
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0009 0.0006 0.0032
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0006 0.0087
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0038 0.019 0.2968
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0096 0.0558 0.1844
Brugia malayi dehydrogenases, short chain protein 2 0.0009 0.0006 0.0019
Loa Loa (eye worm) nuclear factor I 0.0009 0.0012 0.0038
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0443 0.0803
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.031 0.1612
Trypanosoma brucei glucose transporter, putative 0.0097 0.0563 0.8783
Brugia malayi acetyltransferase, GNAT family protein 0.0286 0.1748 0.5778
Echinococcus multilocularis nibrin 0.001 0.0012 0.0012
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0018 0.0063 0.0693
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0009 0.0006 0.0006
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0009 0.0006 0.0029
Trypanosoma brucei short-chain dehydrogenase, putative 0.0009 0.0006 0.0087
Trypanosoma brucei glucose transporter, putative 0.0097 0.0563 0.8783
Leishmania major importin beta-1 subunit, putative 0.0023 0.0099 0.1543
Trichomonas vaginalis sugar transporter, putative 0.0097 0.0563 0.2929
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0051 0.0056
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Echinococcus granulosus dna polymerase kappa 0.0019 0.0073 0.0081
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0006 0.0004
Leishmania major hypothetical protein, conserved 0.0044 0.0229 0.3573
Schistosoma mansoni ferritin light chain 0.0009 0.0007 0.0007
Echinococcus granulosus SPRY domain containing protein 0.0008 0.0002 0.0002
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0065 0.0362 0.399
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.001 0.0012 0.0135
Echinococcus granulosus carbonyl reductase 1 0.0009 0.0006 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0014 0.0046
Leishmania major glucose transporter, lmgt1 0.0097 0.0563 0.8783
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0009 0.0006 0.0087
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.001 0.0012 0.0022
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0009 0.0006 0.0006
Trypanosoma brucei glucose transporter 1E 0.0097 0.0563 0.8783
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0009 0.0006 0.0019
Loa Loa (eye worm) oxidoreductase 0.0009 0.0006 0.0019
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0018 0.0063 0.0208
Leishmania major glucose transporter, lmgt3 0.0097 0.0563 0.8783
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.011 0.0641 1
Trichomonas vaginalis aspartyl/lysyl-tRNA synthetase, putative 0.0011 0.0018 0.0095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0133 0.044
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0007
Brugia malayi topoisomerase 0.001 0.0012 0.004
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0014 0.0093
Echinococcus granulosus expressed protein 0.0009 0.0007 0.0007
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0011 0.0018 0.0285
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0014 0.0015
Schistosoma mansoni inositol monophosphatase 0.0073 0.041 0.0451
Loa Loa (eye worm) hypothetical protein 0.0038 0.019 0.0628
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0064
Schistosoma mansoni sugar transporter 0.0044 0.0229 0.0252
Schistosoma mansoni DNA repair and recombination protein rad54-related 0.0008 0.0002 0.0002
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0105 0.0612 0.2025
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0229 0.1191
Schistosoma mansoni retinal dehydrogenase 0.0009 0.0006 0.0006
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0014 0.0093
Loa Loa (eye worm) hypothetical protein 0.0013 0.0031 0.0101
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0009 0.0006 0.0029
Onchocerca volvulus 0.0038 0.019 0.1276
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0393 0.1301
Loa Loa (eye worm) hypothetical protein 0.0019 0.0073 0.0242
Brugia malayi Probable ClpP-like protease 0.0078 0.0443 0.1465
Onchocerca volvulus 0.0044 0.0229 0.1536
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0022 0.0088 0.0968
Schistosoma mansoni glucose transporter 0.0044 0.0229 0.0252
Echinococcus multilocularis smad 0.0017 0.006 0.006
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0367 0.0403
Trypanosoma cruzi sugar transporter, putative 0.0044 0.0229 0.3573
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0008 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0245 0.149 0.4924
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.031 0.1023
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0299 0.0329
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.041 0.6396
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Echinococcus granulosus histidyl tRNA synthetase 0.0011 0.0019 0.002
Onchocerca volvulus 0.0044 0.0229 0.1536
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0014 0.0015
Echinococcus granulosus neuropeptide receptor A26 0.0467 0.2884 0.3172
Echinococcus granulosus Smad4 0.0017 0.006 0.0066
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.031 0.4834
Onchocerca volvulus 0.0009 0.0006 0.0038
Brugia malayi MH2 domain containing protein 0.0017 0.006 0.0198
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0096 0.0558 0.0558
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0398 0.0437
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0006 0.0087
Echinococcus multilocularis neuropeptide s receptor 0.0467 0.2884 0.2884
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0096 0.0558 0.0613
Toxoplasma gondii oxidoreductase, putative 0.0009 0.0006 0.001
Mycobacterium ulcerans ketoacyl reductase 0.0009 0.0006 0.0062
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0019
Chlamydia trachomatis DNA ligase 0.001 0.0012 0.0276
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0014 0.0046
Plasmodium falciparum steroid dehydrogenase, putative 0.0009 0.0006 0.0004
Leishmania major glucose transporter/membrane transporter D2, putative 0.0097 0.0563 0.8783
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0009 0.0006 0.0062
Schistosoma mansoni intermediate filament proteins 0.0027 0.0121 0.0133
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Schistosoma mansoni tar DNA-binding protein 0.007 0.0393 0.0433
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.031 0.4834
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0009 0.0006 0.0087
Echinococcus multilocularis transfer RNA-Lys 0.0108 0.063 0.063
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0085 0.1331
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.005 0.026
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0009 0.0006 0.0006
Brugia malayi glycyl-tRNA synthetase 0.0018 0.0063 0.0208
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Leishmania major hypothetical protein, conserved 0.0016 0.005 0.0779
Plasmodium falciparum glycine--tRNA ligase 0.0011 0.0019 0.002
Echinococcus granulosus inositol monophosphatase 1 0.0073 0.041 0.0451
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0006 0.0006
Treponema pallidum asparaginyl-tRNA synthetase 0.0011 0.0018 0.0267
Mycobacterium ulcerans short chain dehydrogenase 0.0009 0.0006 0.0062
Trypanosoma brucei sugar transporter, putative 0.0044 0.0229 0.3573
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0073 0.041 0.7346
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0018 0.0063 0.1307
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0073 0.0242
Giardia lamblia Prolyl-tRNA synthetase 0.0094 0.0543 1
Echinococcus multilocularis SPRY domain containing protein 0.0008 0.0002 0.0002
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0073 0.0073
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.005 0.0779
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0046
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0006 0.0006
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0274 0.0301
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0073 0.1143
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0229 0.1191
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0009 0.0006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0094 0.0543 0.1794
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0012 0.0191
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0009 0.0006 0.0087
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0038 0.019 0.2968
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0094 0.0543 0.0543
Leishmania major short chain dehydrogenase/reductase, putative 0.0009 0.0006 0.0087
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Toxoplasma gondii glycyl-tRNA synthetase 0.0018 0.0063 0.0114
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0073 0.0412 0.6427
Echinococcus granulosus steroid dehydrogenase 0.0009 0.0006 0.0006
Trypanosoma cruzi replication Factor A 28 kDa subunit, putative 0.0009 0.0006 0.0097
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0011 0.0019 0.029
Schistosoma mansoni microtubule-associated protein tau 0.1455 0.9094 1
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0038 0.019 0.429
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0009 0.0006 0.0062
Loa Loa (eye worm) hypothetical protein 0.0489 0.3025 1
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0018 0.002
Onchocerca volvulus 0.0044 0.0229 0.1536
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.004
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0012 0.0064
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0009 0.0006 0.0087
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0085 0.0282
Brugia malayi Major Facilitator Superfamily protein 0.0044 0.0229 0.0757
Brugia malayi RNA binding protein 0.007 0.0393 0.1301
Onchocerca volvulus 0.0044 0.0229 0.1536
Loa Loa (eye worm) TAR-binding protein 0.007 0.0393 0.1301
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.001
Brugia malayi TAR-binding protein 0.007 0.0393 0.1301
Brugia malayi major facilitator superfamily protein 0.0044 0.0229 0.0757
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0009 0.0006 0.0062
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0038 0.019 0.2968
Giardia lamblia Glycyl-tRNA synthetase 0.0018 0.0063 0.1157
Treponema pallidum glycyl-tRNA synthetase 0.0011 0.0019 0.0274
Leishmania major quinonoid dihydropteridine reductase 0.0009 0.0006 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0014 0.0046
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0009 0.0006 0.0038
Toxoplasma gondii sugar transporter ST2 0.0044 0.0229 0.0415
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0014 0.0046
Brugia malayi intermediate filament protein 0.0027 0.0121 0.0401
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Schistosoma mansoni short chain dehydrogenase 0.0009 0.0006 0.0006
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0367 0.0367
Plasmodium vivax threonine--tRNA ligase, putative 0.0018 0.0063 0.0073
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0009 0.0006 0.0087
Plasmodium falciparum histidine--tRNA ligase, putative 0.0011 0.0019 0.002
Echinococcus multilocularis replication factor c subunit 1 0.001 0.0012 0.0012
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0073 0.0412 0.0453
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0229 0.1191
Treponema pallidum prolyl-tRNA synthetase 0.0033 0.0161 0.353
Loa Loa (eye worm) hypothetical protein 0.0094 0.0543 0.1794
Mycobacterium ulcerans integral membrane transport protein 0.0044 0.0229 0.2524
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0018 0.0063 0.0063
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0073 0.0808
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0073 0.1143
Mycobacterium tuberculosis Probable oxidoreductase 0.0009 0.0006 0.0062
Schistosoma mansoni steroid dehydrogenase 0.0009 0.0006 0.0006
Schistosoma mansoni smad1 5 8 and 0.0017 0.006 0.0066
Trypanosoma cruzi short chain dehydrogenase, putative 0.0009 0.0006 0.0087
Leishmania major 3-keto-dihydrosphingosine reductase 0.0009 0.0006 0.0087
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0022 0.0088 0.0968
Loa Loa (eye worm) hypothetical protein 0.0044 0.0229 0.0757
Trichomonas vaginalis conserved hypothetical protein 0.0097 0.0563 0.2929
Brugia malayi hypothetical protein 0.0009 0.0006 0.0019
Onchocerca volvulus 0.0009 0.0006 0.0038
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0022 0.0088 0.0968
Mycobacterium ulcerans lysyl-tRNA synthetase 0.007 0.0391 0.4318
Brugia malayi Sugar transporter family protein 0.0313 0.1921 0.635
Brugia malayi MH2 domain containing protein 0.0008 0 0.0001
Echinococcus granulosus dna repair and recombination protein rad54 0.0008 0.0002 0.0002
Giardia lamblia Sugar-proton symporter 0.0044 0.0229 0.4217
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0094 0.0543 0.9729
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0094 0.0543 0.1794
Mycobacterium ulcerans short-chain dehydrogenase 0.0009 0.0006 0.0062
Echinococcus granulosus solute carrier family 22 0.0044 0.0229 0.0252
Plasmodium vivax importin-beta 2, putative 0.0029 0.0133 0.0158
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0088 0.0968
Toxoplasma gondii replication factor-a protein 1 (rpa1) subfamily protein 0.0009 0.0006 0.0011
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.031 0.0561
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0096 0.0558 0.1844
Brugia malayi recombination factor GdRad54 0.0008 0.0002 0.0007
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0009 0.0006 0.001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0051 0.0051
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0094 0.0543 0.5986
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0507 0.3136 0.3772
Brugia malayi MAP kinase sur-1 0.0057 0.031 0.1023
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0443 0.0803
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0044 0.0229 0.5103
Trypanosoma cruzi histidyl-tRNA synthetase 0.0011 0.0019 0.029
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.0019
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.011 0.0641 0.1161
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.006 0.0066
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0009 0.0006 0.0006
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0018 0.0063 0.0208
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0009 0.0006 0.0062
Onchocerca volvulus 0.001 0.0014 0.0093
Mycobacterium tuberculosis Possible oxidoreductase 0.0009 0.0006 0.0062
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0038 0.019 0.099
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0009 0.0006 0.0062
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0011 0.0018 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0229 0.1191
Onchocerca volvulus 0.0044 0.0229 0.1536
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0018 0.002
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0044 0.0231 0.36
Schistosoma mansoni smad1 5 8 and 0.0017 0.006 0.0066
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0085 0.01
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0006 0.001
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0121 0.0143

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.0251 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.0119 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.1714 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 11.5821 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 18.3564 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 19.9526 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 20.5962 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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