Detailed information for compound 148742

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 498.576 | Formula: C28H30N6O3
  • H donors: 3 H acceptors: 5 LogP: 3.77 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCN(c1nc(NCc2ccc(cc2)OC)c2c(n1)n(cn2)Cc1ccc2c(c1)cccc2)CCO
  • InChi: 1S/C28H30N6O3/c1-37-24-10-7-20(8-11-24)17-29-26-25-27(32-28(31-26)33(12-14-35)13-15-36)34(19-30-25)18-21-6-9-22-4-2-3-5-23(22)16-21/h2-11,16,19,35-36H,12-15,17-18H2,1H3,(H,29,31,32)
  • InChiKey: XYKSIWFXMJCTPC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cyclin E2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Chlamydia trachomatis thio-specific antioxidant peroxidase 0.0142 0.2515 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.017 0.303 0.9683
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0338 0.1308
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0006 0.001 0.002
Brugia malayi thioredoxin peroxidase, identical 0.0142 0.2515 0.8029
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0057
Plasmodium vivax heterochromatin protein 1, putative 0.001 0.0069 0.0234
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0008 0.0046 0.014
Mycobacterium ulcerans ketoacyl reductase 0.0008 0.0046 0.0167
Mycobacterium tuberculosis Probable bacterioferritin comigratory protein Bcp 0.0033 0.0497 0.0796
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.001 0.0069 0.0234
Loa Loa (eye worm) hypothetical protein 0.001 0.0069 0.019
Entamoeba histolytica peroxiredoxin 0.0142 0.2515 0.567
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Onchocerca volvulus Sepiapterin reductase homolog 0.0008 0.0046 0.01
Loa Loa (eye worm) CXXC zinc finger family protein 0.002 0.0257 0.0791
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0338 0.1308
Giardia lamblia Kinase, PLK 0.008 0.1365 0.3066
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Loa Loa (eye worm) oxidoreductase 0.0008 0.0046 0.0114
Mycobacterium leprae Conserved hypothetical protein 0.001 0.0069 0.0185
Echinococcus granulosus L aminoadipate semialdehyde 0.007 0.1182 0.2326
Brugia malayi hypothetical protein 0.0034 0.0516 0.1622
Loa Loa (eye worm) hypothetical protein 0.0017 0.0205 0.0626
Onchocerca volvulus 0.0008 0.0046 0.01
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0046 0.014
Schistosoma mansoni thioredoxin peroxidase 0.0142 0.2515 0.4947
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0152 0.032
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0006 0.0011 0.0021
Brugia malayi Cyclin, N-terminal domain containing protein 0.0021 0.0289 0.0894
Echinococcus granulosus Polycystic kidney disease protein 0.0017 0.0198 0.039
Trypanosoma cruzi cytochrome p450-like protein, putative 0.001 0.0069 0.0232
Mycobacterium ulcerans oxidoreductase 0.0008 0.0046 0.0167
Onchocerca volvulus 0.0008 0.0046 0.01
Trichomonas vaginalis peroxiredoxins, prx-1, prx-2, prx-3, putative 0.0142 0.2515 0.567
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0054 0.0885 0.2806
Loa Loa (eye worm) hypothetical protein 0.001 0.0069 0.019
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0008 0.0046 0.0057
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0008 0.0046 0.0114
Schistosoma mansoni chromobox protein 0.0058 0.0973 0.1915
Trichomonas vaginalis esterase, putative 0.0053 0.0867 0.1939
Toxoplasma gondii oxidoreductase, putative 0.0008 0.0046 0.014
Loa Loa (eye worm) hypothetical protein 0.001 0.0069 0.019
Toxoplasma gondii NADPH-glutathione reductase 0.0024 0.0338 0.1308
Loa Loa (eye worm) CHromoDomain protein family member 0.0011 0.009 0.0257
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0046 0.0057
Brugia malayi Cyclin, N-terminal domain containing protein 0.0021 0.0289 0.0894
Entamoeba histolytica hypothetical protein 0.002 0.0255 0.0554
Trypanosoma cruzi CYC2-like cyclin, putative 0.0021 0.0289 0.1111
Onchocerca volvulus 0.0008 0.0046 0.01
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0069 0.0133
Mycobacterium tuberculosis Probable esterase LipL 0.0053 0.0867 0.1402
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0046 0.014
Echinococcus granulosus steroid dehydrogenase 0.0008 0.0046 0.009
Mycobacterium ulcerans soluble secreted antigen Mpt53 precursor 0.0033 0.0497 0.2319
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0152 0.032
Loa Loa (eye worm) oxidoreductase 0.0008 0.0046 0.0114
Entamoeba histolytica peroxiredoxin, putative 0.0033 0.0497 0.1101
Mycobacterium ulcerans alkyl hydroperoxide reductase C protein AhpC 0.0097 0.169 0.8007
Brugia malayi MH2 domain containing protein 0.008 0.1381 0.4394
Mycobacterium ulcerans ketoacyl reductase 0.0008 0.0046 0.0167
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.001 0.0069 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0289 0.063
Echinococcus multilocularis dnaJ subfamily B 0.0281 0.5083 0.5083
Loa Loa (eye worm) glutathione reductase 0.007 0.1179 0.3747
Loa Loa (eye worm) hypothetical protein 0.0016 0.0193 0.0588
Echinococcus granulosus mitogen activated protein kinase 3 0.004 0.0641 0.1261
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Leishmania major tryparedoxin peroxidase 0.0142 0.2515 1
Mycobacterium tuberculosis Soluble secreted antigen Mpt53 precursor 0.0033 0.0497 0.0796
Brugia malayi Cytochrome P450 family protein 0.001 0.0069 0.0189
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0022 0.0044
Loa Loa (eye worm) heterochromatin protein 1 0.0058 0.0973 0.3088
Trypanosoma cruzi tryparedoxin peroxidase, putative 0.0142 0.2515 1
Brugia malayi hypothetical protein 0.0017 0.0198 0.0604
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.001 0.0069 0.0277
Echinococcus granulosus thioredoxin glutathione reductase 0.007 0.1187 0.2334
Trypanosoma cruzi peroxidoxin 0.0142 0.2515 1
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0973 0.218
Mycobacterium ulcerans hypothetical protein 0.0033 0.0497 0.2319
Echinococcus multilocularis cyclin b3 0.0021 0.0289 0.0289
Trichomonas vaginalis CAMK family protein kinase 0.008 0.1365 0.3066
Schistosoma mansoni hypothetical protein 0.0223 0.4014 0.7897
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0057
Schistosoma mansoni hypothetical protein 0.0054 0.0885 0.1742
Trichomonas vaginalis alkyl hydroperoxide reductase, subunit C, putative 0.0142 0.2515 0.567
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0006 0.0011 0.0002
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0046 0.014
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.001 0.0069 0.0069
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0024 0.0338 0.1308
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0046 0.0046
Loa Loa (eye worm) thioredoxin reductase 0.007 0.1179 0.3747
Loa Loa (eye worm) hypothetical protein 0.0016 0.0193 0.0588
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0338 0.1308
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Mycobacterium leprae conserved hypothetical protein 0.002 0.0255 0.0778
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0069 0.0133
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Trichomonas vaginalis alkyl hydroperoxide reductase, subunit C, putative 0.0142 0.2515 0.567
Plasmodium vivax glutathione reductase, putative 0.007 0.1179 0.4665
Brugia malayi Retinol dehydrogenase 12 0.0008 0.0046 0.0114
Mycobacterium tuberculosis Probable peroxiredoxin AhpE 0.0097 0.169 0.2749
Leishmania major short chain dehydrogenase/reductase, putative 0.0008 0.0046 0.014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0338 0.1308
Mycobacterium tuberculosis Probable dehydrogenase 0.0159 0.2827 0.4611
Loa Loa (eye worm) doublecortin family protein 0.0017 0.0198 0.0604
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0008 0.0046 0.0057
Trichomonas vaginalis cyclin D, putative 0.0021 0.0289 0.063
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0046 0.0057
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0008 0.0046 0.014
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.001 0.0069 0.0095
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0022 0.0022
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0167
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0008 0.0046 0.0167
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0006 0.001 0.002
Leishmania major tryparedoxin peroxidase 0.0142 0.2515 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0024 0.0338 0.1052
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0008 0.0046 0.0167
Plasmodium vivax steroid dehydrogenase, putative 0.0008 0.0046 0.014
Brugia malayi F/Y-rich N-terminus family protein 0.0007 0.0021 0.0035
Echinococcus multilocularis mitogen activated protein kinase 0.004 0.0641 0.0641
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0245 0.4427 1
Plasmodium vivax multidomain scavenger receptor, putative 0.0017 0.0198 0.0749
Mycobacterium leprae ALKYL HYDROPEROXIDE REDUCTASE C PROTEIN AHPC (ALKYL HYDROPEROXIDASE C) 0.0097 0.169 0.5341
Plasmodium falciparum glutathione reductase 0.007 0.1179 0.4665
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0057
Trypanosoma brucei hypothetical protein, conserved 0.0053 0.0867 0.3419
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.002 0.0255 0.04
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0175 0.3129 1
Trypanosoma cruzi tryparedoxin peroxidase 0.0142 0.2515 1
Schistosoma mansoni cyclin B 0.0021 0.0289 0.0568
Echinococcus granulosus hypothetical protein 0.0008 0.0046 0.009
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.001 0.0069 0.0095
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0024 0.0338 0.0338
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0046 0.009
Giardia lamblia Peroxiredoxin 1 0.0142 0.2515 0.567
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0498 0.1104
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0159 0.2827 0.4611
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0046 0.0046
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0167
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Echinococcus multilocularis cyclins 0.0021 0.0289 0.0289
Trichomonas vaginalis alkyl hydroperoxide reductase, subunit C, putative 0.0142 0.2515 0.567
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0046 0.014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0152 0.032
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0046 0.009
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.001 0.0069 0.0095
Onchocerca volvulus 0.0035 0.054 0.1488
Echinococcus granulosus cytochrome P450 2K1 0.001 0.0069 0.0135
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Mycobacterium tuberculosis Possible oxidoreductase 0.0008 0.0046 0.0057
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Onchocerca volvulus 0.001 0.0069 0.0166
Trichomonas vaginalis CAMK family protein kinase 0.008 0.1365 0.3066
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0008 0.0046 0.009
Schistosoma mansoni chromobox protein 0.0058 0.0973 0.1915
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0245 0.4427 1
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0008 0.0046 0.0079
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0867 0.3419
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.002 0.0255 0.0976
Trichomonas vaginalis peroxiredoxin, putative 0.0109 0.191 0.4301
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.001 0.0069 0.0277
Echinococcus multilocularis retinol dehydrogenase 11 0.0008 0.0046 0.0046
Leishmania major hypothetical protein, conserved 0.0008 0.0046 0.014
Schistosoma mansoni cpg binding protein 0.0021 0.0278 0.0546
Loa Loa (eye worm) hypothetical protein 0.001 0.0069 0.019
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Plasmodium vivax thioredoxin reductase, putative 0.007 0.1179 0.4665
Trypanosoma brucei cytochrome P450, putative 0.001 0.0069 0.0232
Entamoeba histolytica hypothetical protein 0.001 0.0069 0.0133
Echinococcus granulosus chromobox protein 2 0.001 0.0069 0.0136
Brugia malayi Associated with TFs and helicases family protein 0.001 0.0069 0.019
Entamoeba histolytica serine/threonine protein kinase, putative 0.008 0.1365 0.3066
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0159 0.2827 0.4611
Trypanosoma cruzi tryparedoxin peroxidase, putative 0.0142 0.2515 1
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0008 0.0046 0.0046
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0008 0.0046 0.01
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0167
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.001 0.0069 0.0277
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0057
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.001 0.0069 0.0277
Schistosoma mansoni chromobox protein 0.001 0.0069 0.0136
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0046 0.014
Leishmania major cyclin 0.0021 0.0289 0.1111
Loa Loa (eye worm) MH2 domain-containing protein 0.008 0.1381 0.4394
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0008 0.0046 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.008 0.1365 0.3066
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.001 0.0069 0.0136
Echinococcus granulosus retinol dehydrogenase 11 0.0008 0.0046 0.009
Brugia malayi Calcitonin receptor-like protein seb-1 0.017 0.303 0.9683
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0024 0.0339 0.0666
Echinococcus multilocularis ecdysone induced protein 78C 0.0006 0.001 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0245 0.4427 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0054 0.0885 0.1742
Mycobacterium ulcerans peroxidoxin BcpB 0.0033 0.0497 0.2319
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0015 0.0172 0.0339
Treponema pallidum 4'-phosphopantetheinyl transferase 0.002 0.0255 0.0554
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0006 0.0011 0.0021
Schistosoma mansoni glutamate synthase 0.0006 0.0011 0.0021
Loa Loa (eye worm) hypothetical protein 0.0008 0.0046 0.0114
Entamoeba histolytica peroxiredoxin, putative 0.0033 0.0497 0.1101
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0159 0.2827 0.4611
Leishmania major tryparedoxin peroxidase 0.0142 0.2515 1
Onchocerca volvulus 0.002 0.0257 0.0692
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0245 0.4427 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0498 0.1566
Leishmania major trypanothione reductase 0.007 0.1179 0.4665
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0006 0.0011 0.0002
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0046 0.0057
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0025 0.0364 0.0364
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.002 0.0255 0.0976
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Schistosoma mansoni hypothetical protein 0.0006 0.0011 0.0021
Brugia malayi M-phase phosphoprotein, mpp8 0.001 0.0069 0.019
Trichomonas vaginalis cyclin B, putative 0.0021 0.0289 0.063
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Schistosoma mansoni carbonyl reductase 0.0008 0.0046 0.009
Brugia malayi oxidoreductase 0.0008 0.0046 0.0114
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0046 0.014
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0006 0.001 0.002
Echinococcus multilocularis beta LACTamase domain containing family member 0.0053 0.0867 0.0867
Mycobacterium tuberculosis Probable lipase LipE 0.0053 0.0867 0.1402
Echinococcus granulosus histone lysine methyltransferase setb 0.0025 0.0364 0.0715
Leishmania major cytochrome p450-like protein 0.001 0.0069 0.0232
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.001 0.0069 0.0133
Echinococcus granulosus hypothetical protein 0.0008 0.0046 0.009
Entamoeba histolytica hypothetical protein, conserved 0.0008 0.0046 0.0079
Onchocerca volvulus 0.0008 0.0046 0.01
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0046 0.0749 0.0749
Mycobacterium tuberculosis Conserved protein 0.0053 0.0867 0.1402
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.001 0.0069 0.0234
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0973 0.218
Brugia malayi Latrophilin receptor protein 2 0.0054 0.0885 0.2806
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0046 0.009
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0625 0.139
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.001 0.0069 0.0277
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0024 0.0338 0.0665
Echinococcus multilocularis Chromobox protein 3 0.001 0.0069 0.0069
Echinococcus multilocularis lamin dm0 0.0035 0.054 0.054
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.0069 0.0189
Loa Loa (eye worm) histone methyltransferase 0.0007 0.0022 0.0039
Onchocerca volvulus 0.0017 0.0198 0.0528
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0069 0.0133
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.001 0.0069 0.0277
Loa Loa (eye worm) hypothetical protein 0.007 0.1182 0.3758
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.0046 0.0167
Loa Loa (eye worm) oxidoreductase 0.0008 0.0046 0.0114
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.008 0.1365 0.5407
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0053 0.0867 0.1705
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Echinococcus granulosus Chromo domain 0.001 0.0069 0.0136
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0008 0.0046 0.0079
Leishmania major short chain dehydrogenase, putative 0.0008 0.0046 0.014
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0024 0.0338 0.1308
Leishmania major cytochrome p450-like protein 0.001 0.0069 0.0232
Trypanosoma cruzi trypanothione reductase, putative 0.007 0.1179 0.4665
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0101 0.1756 0.3455
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Echinococcus multilocularis thioredoxin glutathione reductase 0.007 0.1187 0.1187
Plasmodium vivax thioredoxin peroxidase 2, putative 0.0142 0.2515 1
Loa Loa (eye worm) thioredoxin peroxidase 1 0.0142 0.2515 0.8029
Giardia lamblia Cyclin A 0.0021 0.0289 0.063
Echinococcus granulosus lamin 0.0035 0.054 0.1063
Schistosoma mansoni chromobox protein 0.001 0.0069 0.0136
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0008 0.0046 0.0079
Schistosoma mansoni hypothetical protein 0.0054 0.0885 0.1742
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0008 0.0046 0.014
Brugia malayi serine/threonine-protein kinase plk-2 0.008 0.1365 0.4343
Treponema pallidum alkyl hydroperoxide reductase (ahpC) 0.0142 0.2515 0.567
Loa Loa (eye worm) hypothetical protein 0.0053 0.0867 0.2747
Entamoeba histolytica cyclin, putative 0.0021 0.0289 0.063
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Echinococcus granulosus lipoxygenase domain containing protein 0.0017 0.0198 0.039
Trypanosoma brucei oxidoreductase-like protein 0.0008 0.0046 0.014
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.001 0.0069 0.0136
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.004 0.0641 0.2518
Leishmania major tryparedoxin peroxidase 0.0142 0.2515 1
Echinococcus multilocularis musashi 0.0035 0.054 0.054
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0008 0.0046 0.014
Leishmania major tryparedoxin peroxidase 0.0142 0.2515 1
Plasmodium vivax 1-cys peroxiredoxin 0.0142 0.2515 1
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0008 0.0046 0.0111
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0051 0.0827 0.3259
Echinococcus granulosus dnaJ subfamily B 0.0281 0.5083 1
Trypanosoma brucei mitotic cyclin 6 0.0021 0.0289 0.1111
Schistosoma mansoni retinal dehydrogenase 0.0008 0.0046 0.009
Toxoplasma gondii ABC1 family protein 0.0053 0.0867 0.3419
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0008 0.0046 0.0111
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0176 0.3154 0.5147
Echinococcus granulosus cyclin b3 0.0021 0.0289 0.0568
Schistosoma mansoni glutamate synthase 0.0006 0.0011 0.0021
Echinococcus granulosus Chromobox protein 3 0.001 0.0069 0.0136
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Trypanosoma cruzi short chain dehydrogenase, putative 0.0008 0.0046 0.014
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0069 0.0133
Loa Loa (eye worm) hypothetical protein 0.0008 0.0046 0.0114
Giardia lamblia Hypothetical protein 0.0033 0.0497 0.1101
Mycobacterium ulcerans hypothetical protein 0.0033 0.0497 0.2319
Schistosoma mansoni loxhd1 0.0017 0.0198 0.039
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0008 0.0046 0.0079
Loa Loa (eye worm) beta-lactamase 0.0053 0.0867 0.2747
Trichomonas vaginalis CMGC family protein kinase 0.004 0.0641 0.1427
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0641 0.1261
Entamoeba histolytica peroxiredoxin 0.0142 0.2515 0.567
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0114 0.0233
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0024 0.0338 0.1562
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0057
Entamoeba histolytica short chain dehydrogenase family protein 0.0008 0.0046 0.0079
Loa Loa (eye worm) hypothetical protein 0.0025 0.0364 0.1133
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0046 0.009
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0046 0.014
Brugia malayi SET domain containing protein 0.0011 0.0094 0.027
Entamoeba histolytica peroxiredoxin 0.0142 0.2515 0.567
Plasmodium falciparum thioredoxin reductase 0.007 0.1179 0.4665
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0046 0.014
Trypanosoma cruzi PAB1-binding protein , putative 0.0034 0.0516 0.2018
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0008 0.0046 0.0079
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.0046 0.0167
Leishmania major hypothetical protein, conserved 0.0008 0.0046 0.014
Schistosoma mansoni thyroid hormone receptor 0.0006 0.001 0.002
Entamoeba histolytica short chain dehydrogenase family protein 0.0008 0.0046 0.0079
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0152 0.032
Leishmania major peroxidoxin 0.0142 0.2515 1
Onchocerca volvulus Huntingtin homolog 0.0077 0.1318 0.3668
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.001 0.0069 0.0095
Trypanosoma cruzi polo-like protein kinase, putative 0.008 0.1365 0.5407
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.007 0.1179 0.1913
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0008 0.0046 0.0079
Schistosoma mansoni cyclin B3 0.0021 0.0289 0.0568
Schistosoma mansoni thyroid hormone receptor 0.0006 0.001 0.002
Schistosoma mansoni carbonyl reductase 0.0008 0.0046 0.009
Trichomonas vaginalis CAMK family protein kinase 0.008 0.1365 0.3066
Schistosoma mansoni cytochrome P450 0.001 0.0069 0.0135
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Mycobacterium ulcerans dehydrogenase/reductase 0.0008 0.0046 0.0167
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.0046 0.0167
Brugia malayi hypothetical protein 0.0022 0.0295 0.0914
Leishmania major oxidoreductase-like protein 0.0008 0.0046 0.014
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0024 0.0338 0.1308
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Brugia malayi hypothetical protein 0.0008 0.0046 0.0114
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0018 0.022 0.0673
Echinococcus multilocularis oxidoreductase 0.0008 0.0046 0.0046
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Loa Loa (eye worm) hypothetical protein 0.0054 0.0885 0.2806
Echinococcus granulosus serine:threonine protein kinase PLK1 0.008 0.1365 0.2685
Mycobacterium ulcerans dehydrogenase 0.0008 0.0046 0.0167
Loa Loa (eye worm) hypothetical protein 0.0034 0.0529 0.1662
Leishmania major short chain dehydrogenase/reductase, putative 0.0008 0.0046 0.014
Mycobacterium leprae conserved hypothetical protein 0.0033 0.0497 0.1547
Trypanosoma cruzi tryparedoxin peroxidase, putative 0.0142 0.2515 1
Onchocerca volvulus 0.001 0.0069 0.0166
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Echinococcus multilocularis 0.001 0.0069 0.0069
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0054 0.0885 0.0885
Entamoeba histolytica hypothetical protein 0.001 0.0069 0.0133
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0035 0.0544 0.1499
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0338 0.1308
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.012 0.2107 0.667
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Treponema pallidum fructose-bisphosphate aldolase 0.0245 0.4427 1
Trichomonas vaginalis Heterochromatin protein, putative 0.001 0.0069 0.0133
Entamoeba histolytica hypothetical protein 0.001 0.0069 0.0133
Loa Loa (eye worm) hypothetical protein 0.0008 0.0046 0.0114
Mycobacterium leprae Probable oxidoreductase 0.0008 0.0046 0.0111
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0046 0.009
Schistosoma mansoni hypothetical protein 0.0054 0.0885 0.1742
Schistosoma mansoni RAR-like nuclear receptor 0.0006 0.001 0.002
Trichomonas vaginalis D-aminoacylase, putative 0.0053 0.0867 0.1939
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0046 0.0046
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0019 0.024 0.0736
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0167
Toxoplasma gondii cytochrome p450 superfamily protein 0.001 0.0069 0.0232
Treponema pallidum NADH oxidase 0.0024 0.0338 0.0741
Echinococcus granulosus ecdysone induced protein 78C 0.0006 0.001 0.002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0364 0.0715
Mycobacterium tuberculosis Conserved protein 0.0033 0.0497 0.0796
Plasmodium falciparum ataxin-2 like protein, putative 0.0034 0.0516 0.2018
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0024 0.0338 0.1308
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0006 0.001 0.002
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.004 0.0641 0.2518
Loa Loa (eye worm) hypothetical protein 0.0008 0.0046 0.0114
Mycobacterium ulcerans integral membrane C-type cytochrome biogenesis protein DipZ 0.0033 0.0497 0.2319
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0033 0.0498 0.137
Brugia malayi chromobox protein homolog 3 0.0033 0.0498 0.1566
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0008 0.0046 0.014
Loa Loa (eye worm) hypothetical protein 0.0008 0.0046 0.0114
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0051 0.0827 0.2619
Echinococcus multilocularis steroid dehydrogenase 0.0008 0.0046 0.0046
Mycobacterium tuberculosis Probable hydrolase 0.0053 0.0867 0.1402
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0066 0.1122 0.2517
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0024 0.0338 0.1308
Brugia malayi hypothetical protein 0.0077 0.1318 0.4193
Onchocerca volvulus 0.0035 0.054 0.1488
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0024 0.0338 0.1308
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0024 0.0338 0.1308
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.001 0.0069 0.0232
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Brugia malayi N-terminal motif family protein 0.0098 0.1709 0.5445
Onchocerca volvulus 0.0008 0.0046 0.01
Loa Loa (eye worm) hypothetical protein 0.0017 0.0198 0.0604
Leishmania major hypothetical protein, conserved 0.0034 0.0516 0.2018
Echinococcus multilocularis cyclin B3 1 0.0021 0.0289 0.0289
Echinococcus granulosus RUN 0.0017 0.0198 0.039
Trichomonas vaginalis CAMK family protein kinase 0.008 0.1365 0.3066
Brugia malayi Protein cec-1. 0.001 0.0069 0.019
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.007 0.1182 0.3758
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0008 0.0046 0.0114
Trichomonas vaginalis cyclin A, putative 0.0021 0.0289 0.063
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0046 0.009
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0051 0.0827 0.1627
Echinococcus multilocularis thyroid hormone receptor alpha 0.0006 0.001 0.001
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0024 0.0338 0.1308
Brugia malayi intermediate filament protein 0.0035 0.054 0.17
Echinococcus multilocularis lipoxygenase domain containing protein 0.0017 0.0198 0.0198
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0008 0.0046 0.014
Trichomonas vaginalis D-aminoacylase, putative 0.0053 0.0867 0.1939
Plasmodium falciparum heterochromatin protein 1 0.001 0.0069 0.0234
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.004 0.0641 0.2518
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.004 0.0641 0.2518
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Entamoeba histolytica hypothetical protein, conserved 0.0008 0.0046 0.0079
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0008 0.0046 0.0057
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.001 0.0069 0.0095
Trichomonas vaginalis alkyl hydroperoxide reductase, subunit C, putative 0.0142 0.2515 0.567
Schistosoma mansoni cyclins 0.0021 0.0289 0.0568
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0046 0.014
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0111
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.001 0.0069 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0321 0.0704
Trichomonas vaginalis CMGC family protein kinase 0.004 0.0641 0.1427
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0008 0.0046 0.0057
Echinococcus granulosus cyclins 0.0021 0.0289 0.0568
Entamoeba histolytica peroxiredoxin 0.0142 0.2515 0.567
Echinococcus multilocularis geminin 0.0223 0.4014 0.4014
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0046 0.014
Trypanosoma brucei trypanothione reductase 0.007 0.1179 0.4665
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0008 0.0046 0.014
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0008 0.0046 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.001 0.0069 0.0095
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0152 0.032
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.002 0.0255 0.1166
Schistosoma mansoni chromodomain helicase DNA binding protein 0.001 0.0069 0.0136
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0025 0.0364 0.1409
Loa Loa (eye worm) hypothetical protein 0.0008 0.0046 0.0114
Brugia malayi thioredoxin peroxidase 1 0.0097 0.169 0.5385
Leishmania major short chain dehydrogenase, putative 0.0008 0.0046 0.014
Loa Loa (eye worm) hypothetical protein 0.0116 0.2037 0.65
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Loa Loa (eye worm) helicase 0.001 0.0069 0.019
Onchocerca volvulus 0.0008 0.0046 0.01
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0053 0.0867 0.1402
Schistosoma mansoni coup transcription factor 0.0006 0.001 0.002
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.001 0.0069 0.0277
Toxoplasma gondii peroxiredoxin PRX3 0.0077 0.1322 0.5237
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.012 0.2107 1
Toxoplasma gondii peroxiredoxin 6, putative 0.0142 0.2515 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.0827 0.3892
Brugia malayi Type III restriction enzyme, res subunit family protein 0.001 0.0069 0.019
Loa Loa (eye worm) hypothetical protein 0.0008 0.0046 0.0114
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0152 0.032
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0069 0.0133
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.001 0.0069 0.0095
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.001 0.0069 0.0095
Leishmania major 3-keto-dihydrosphingosine reductase 0.0008 0.0046 0.014
Brugia malayi dehydrogenases, short chain protein 2 0.0008 0.0046 0.0114
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.014
Loa Loa (eye worm) hypothetical protein 0.0053 0.0867 0.2747
Brugia malayi Cytochrome P450 family protein 0.0035 0.0545 0.1714
Echinococcus multilocularis mitogen activated protein kinase 3 0.004 0.0641 0.0641
Loa Loa (eye worm) hypothetical protein 0.001 0.0069 0.019
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0364 0.0715
Echinococcus multilocularis cpg binding protein 0.0021 0.0278 0.0278
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0008 0.0046 0.0111
Loa Loa (eye worm) thioredoxin peroxidase 0.0142 0.2515 0.8029
Schistosoma mansoni intermediate filament proteins 0.0035 0.054 0.1063
Trichomonas vaginalis glutathione reductase, putative 0.0024 0.0338 0.0741
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.002 0.0255 0.0976
Trypanosoma brucei tryparedoxin peroxidase 0.0142 0.2515 1
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0006 0.0011 0.0011
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0245 0.4427 1
Schistosoma mansoni hypothetical protein 0.0116 0.2037 0.4008
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0006 0.001 0.001
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0057
Trypanosoma cruzi short chain dehydrogenase, putative 0.0008 0.0046 0.014
Loa Loa (eye worm) dehydrogenase 0.0008 0.0046 0.0114
Brugia malayi Thioredoxin peroxidase 1 0.0142 0.2515 0.8029
Schistosoma mansoni lamin 0.0035 0.054 0.1063
Trichomonas vaginalis CAMK family protein kinase 0.008 0.1365 0.3066
Plasmodium vivax hypothetical protein, conserved 0.001 0.0069 0.0234
Echinococcus granulosus lamin dm0 0.0035 0.054 0.1063
Onchocerca volvulus 0.0199 0.3575 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0006 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0867 0.2747
Brugia malayi hypothetical protein 0.0017 0.0198 0.0604
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0046 0.009
Schistosoma mansoni steroid hormone receptor ad4bp 0.0006 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.017 0.303 0.9683
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0006 0.001 0.002
Brugia malayi beta-lactamase family protein 0.0053 0.0867 0.2747
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0008 0.0046 0.0057
Brugia malayi Cytochrome P450 family protein 0.001 0.0069 0.0189
Leishmania major dehydrogenase-like protein 0.0008 0.0046 0.014
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0167
Schistosoma mansoni disulfide oxidoreductase 0.0006 0.0011 0.0021
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.001 0.0069 0.0095
Echinococcus multilocularis chromobox protein 2 0.001 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0034 0.0516 0.1622
Echinococcus multilocularis conserved hypothetical protein 0.0008 0.0046 0.0046
Entamoeba histolytica peroxiredoxin 0.0142 0.2515 0.567
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0046 0.0079
Toxoplasma gondii hypothetical protein 0.0016 0.0193 0.0729
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0006 0.0011 0.0011
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.008 0.1365 0.1365
Echinococcus multilocularis RUN 0.0017 0.0198 0.0198
Trypanosoma cruzi cyclin, putative 0.0021 0.0289 0.1111
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0245 0.4427 1
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0046 0.0046
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0046 0.0749 0.1473
Mycobacterium tuberculosis Alkyl hydroperoxide reductase C protein AhpC (alkyl hydroperoxidase C) 0.0097 0.169 0.2749
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0006 0.0011 0.0021
Echinococcus granulosus lipoxygenase domain containing protein 0.0017 0.0198 0.039
Mycobacterium ulcerans oxidoreductase 0.0008 0.0046 0.0167
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0046 0.014
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0008 0.0046 0.014
Trichomonas vaginalis peroxiredoxins, prx-1, prx-2, prx-3, putative 0.0033 0.0497 0.1101
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0046 0.014
Trypanosoma cruzi cyclin, putative 0.0021 0.0289 0.1111
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Brugia malayi Dehydrogenases, short chain protein 2 0.0008 0.0046 0.0114
Schistosoma mansoni carbonyl reductase 0.0008 0.0046 0.009
Schistosoma mansoni rab6-interacting 0.0017 0.0198 0.039
Loa Loa (eye worm) hypothetical protein 0.0008 0.0046 0.0114
Trichomonas vaginalis cyclins, putative 0.0021 0.0289 0.063
Echinococcus granulosus cyclins 0.0021 0.0289 0.0568
Plasmodium falciparum glutathione reductase 0.0024 0.0338 0.1308
Brugia malayi Heterochromatin protein 1 0.0058 0.0973 0.3088
Onchocerca volvulus 0.0006 0.0011 0.0002
Loa Loa (eye worm) hypothetical protein 0.0077 0.1318 0.4193
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0021 0.0289 0.0568
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0101 0.1756 0.3455
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0625 0.139
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0006 0.001 0.002
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.001 0.0069 0.0277
Leishmania major pteridine reductase 1 0.0008 0.0046 0.014
Leishmania major hypothetical protein, conserved 0.0008 0.0046 0.014
Brugia malayi latrophilin 2 splice variant baaae 0.0116 0.2037 0.65
Echinococcus multilocularis lamin 0.0035 0.054 0.054
Brugia malayi hypothetical protein 0.0008 0.0046 0.0114
Trypanosoma brucei tryparedoxin peroxidase 0.0142 0.2515 1
Onchocerca volvulus 0.0053 0.0867 0.2403
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.001 0.0069 0.0232
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0008 0.0046 0.014
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0101 0.1756 0.1756
Brugia malayi beta-lactamase family protein 0.0053 0.0867 0.2747
Giardia lamblia FixW protein, putative 0.0033 0.0497 0.1101
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0101 0.1756 0.3455
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Schistosoma mansoni thioredoxin peroxidase 0.0142 0.2515 0.4947
Loa Loa (eye worm) hypothetical protein 0.0008 0.0046 0.0114
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.001 0.0069 0.0095
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0006 0.0011 0.0002
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0101 0.1756 0.5598
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0051 0.0827 0.3892
Echinococcus granulosus cpg binding protein 0.0021 0.0278 0.0546
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0046 0.0046
Wolbachia endosymbiont of Brugia malayi peroxiredoxin 0.0142 0.2515 1
Mycobacterium leprae Probable bacterioferritin comigratory protein Bcp 0.0033 0.0497 0.1547
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0008 0.0046 0.0046
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0053 0.0867 0.4083
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0008 0.0046 0.014
Brugia malayi cytochrome P450 0.001 0.0069 0.0189
Echinococcus granulosus chromobox protein 1 0.0058 0.0973 0.1915
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.001 0.0069 0.0133
Brugia malayi AhpC/TSA family protein 0.0097 0.169 0.5385
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0544 0.1208
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.007 0.1182 0.2326
Loa Loa (eye worm) hypothetical protein 0.0008 0.0046 0.0114
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0006 0.001 0.001
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0024 0.0338 0.1562
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0069 0.0133
Echinococcus multilocularis cyclins 0.0021 0.0289 0.0289
Plasmodium vivax hypothetical protein, conserved 0.001 0.0069 0.0234
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.014
Trypanosoma cruzi cyclin 6, putative 0.0021 0.0289 0.1111
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0111
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0101 0.1756 0.5598
Onchocerca volvulus 0.0008 0.0046 0.01
Schistosoma mansoni glutamate synthase 0.0006 0.0011 0.0021
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0006 0.001 0.001
Trichomonas vaginalis alkyl hydroperoxide reductase, subunit C, putative 0.0142 0.2515 0.567
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.001 0.0069 0.0095
Brugia malayi Intermediate filament tail domain containing protein 0.0035 0.054 0.17
Schistosoma mansoni peroxiredoxins prx-1 prx-2 prx-3 0.0142 0.2515 0.4947
Plasmodium falciparum LCCL domain-containing protein 0.0017 0.0198 0.0749
Trichomonas vaginalis cyclins, putative 0.0021 0.0289 0.063
Onchocerca volvulus 0.0021 0.0289 0.0782
Leishmania major hypothetical protein, conserved 0.0008 0.0046 0.014
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0024 0.0338 0.1308
Plasmodium vivax hypothetical protein, conserved 0.0053 0.0867 0.3419
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0046 0.0057
Mycobacterium ulcerans thioredoxin protein 0.0033 0.0497 0.2319
Mycobacterium ulcerans lipase LipD 0.0053 0.0867 0.4083
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Mycobacterium tuberculosis Probable lipase LipD 0.0053 0.0867 0.1402
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0338 0.1308
Trichomonas vaginalis cyclins, putative 0.0021 0.0289 0.063
Onchocerca volvulus 0.0008 0.0046 0.01
Plasmodium vivax ataxin-2 like protein, putative 0.0034 0.0516 0.2018
Toxoplasma gondii histone lysine methyltransferase SET1 0.0038 0.06 0.2353
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0338 0.1308
Echinococcus multilocularis Peroxiredoxin 2 0.0142 0.2515 0.2515
Schistosoma mansoni kinase 0.0041 0.0644 0.1267
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.001 0.0069 0.0095
Echinococcus granulosus retinol dehydrogenase 11 0.0008 0.0046 0.009
Giardia lamblia Peroxiredoxin 1 0.0142 0.2515 0.567
Loa Loa (eye worm) cyclin domain-containing protein 0.0021 0.0289 0.0894
Echinococcus granulosus cyclin B 0.0021 0.0289 0.0568
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0498 0.1104
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0046 0.009
Echinococcus granulosus mitogen activated protein kinase 0.004 0.0641 0.1261
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0051 0.0827 0.1336
Loa Loa (eye worm) transcription factor SMAD2 0.008 0.1381 0.4394
Echinococcus multilocularis cyclins 0.0021 0.0289 0.0289
Schistosoma mansoni hypothetical protein 0.0223 0.4014 0.7897
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.001 0.0069 0.0234
Onchocerca volvulus 0.0008 0.0046 0.01
Plasmodium vivax SET domain protein, putative 0.0025 0.0364 0.1409
Mycobacterium tuberculosis Unknown protein 0.0033 0.0497 0.0796
Echinococcus granulosus thioredoxin peroxidase 0.0142 0.2515 0.4947
Echinococcus multilocularis cyclins 0.0021 0.0289 0.0289
Trichomonas vaginalis cyclin D, putative 0.0021 0.0289 0.063
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0054 0.0885 0.0885
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0006 0.001 0.002
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0008 0.0046 0.014
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0054 0.0885 0.1742
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0006 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0289 0.0894
Brugia malayi CXXC zinc finger family protein 0.002 0.0257 0.0791
Leishmania major cytochrome p450-like protein 0.001 0.0069 0.0232
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0245 0.4427 1
Brugia malayi Pre-SET motif family protein 0.0175 0.3129 1
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0008 0.0046 0.014
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.001 0.0069 0.0277
Onchocerca volvulus 0.0053 0.0867 0.2403
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0008 0.0046 0.014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0006 0.001 0.001
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0046 0.014
Schistosoma mansoni nuclear hormone receptor 0.0006 0.001 0.002
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0008 0.0046 0.0057
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0167
Trypanosoma cruzi polo-like protein kinase, putative 0.008 0.1365 0.5407
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0006 0.0011 0.0021
Loa Loa (eye worm) pigment dispersing factor receptor c 0.017 0.303 0.9683
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0008 0.0046 0.014
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.002 0.0255 0.1166
Mycobacterium tuberculosis Possible integral membrane C-type cytochrome biogenesis protein DipZ 0.0033 0.0497 0.0796
Onchocerca volvulus Huntingtin homolog 0.0077 0.1318 0.3668
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.001 0.0069 0.0234
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0025 0.0364 0.0364
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.001 0.0069 0.0095
Trichomonas vaginalis cyclin B, putative 0.0021 0.0289 0.063
Brugia malayi cytoplasmic intermediate filament protein 0.0019 0.024 0.0736
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0867 0.3419
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0008 0.0046 0.009
Trypanosoma brucei hypothetical protein, conserved 0.002 0.0255 0.0976
Entamoeba histolytica cyclin family protein 0.0021 0.0289 0.063
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0046 0.014
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0006 0.001 0.002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0338 0.1308
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.001 0.0069 0.0095
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.004 0.0641 0.2518
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0008 0.0046 0.014
Brugia malayi Cyclin, N-terminal domain containing protein 0.0021 0.0289 0.0894
Trypanosoma brucei polo-like protein kinase 0.008 0.1365 0.5407
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0035 0.054 0.17
Brugia malayi glutamate synthase 0.0006 0.0011 0.0002
Giardia lamblia Kinase, CMGC MAPK 0.004 0.0641 0.1427
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0101 0.1756 0.3455
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0008 0.0046 0.014
Trichomonas vaginalis mercuric reductase, putative 0.0024 0.0338 0.0741
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0046 0.0079
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0338 0.1308
Echinococcus multilocularis steroid dehydrogenase 0.0008 0.0046 0.0046
Echinococcus granulosus cyclins 0.0021 0.0289 0.0568
Echinococcus multilocularis thioredoxin dependent peroxide reductase 0.0142 0.2515 0.2515
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0046 0.0079
Mycobacterium ulcerans short-chain type oxidoreductase 0.0008 0.0046 0.0167
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.001 0.0069 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0069 0.0133
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0167
Loa Loa (eye worm) programmed cell death 8 0.0006 0.0011 0.0002
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0017 0.0205 0.0205
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0046 0.009
Trichomonas vaginalis cyclins, putative 0.0021 0.0289 0.063
Mycobacterium ulcerans carveol-like dehydrogenase 0.0008 0.0046 0.0167
Plasmodium falciparum thioredoxin reductase 0.0024 0.0338 0.1308
Toxoplasma gondii alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen, putative 0.0142 0.2515 1
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0008 0.0046 0.01
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0338 0.1308
Brugia malayi glutathione reductase 0.007 0.1179 0.3747
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0006 0.0011 0.0021
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0008 0.0046 0.0046
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0008 0.0046 0.0114
Brugia malayi Doublecortin family protein 0.0017 0.0198 0.0604
Loa Loa (eye worm) oxidoreductase 0.0008 0.0046 0.0114
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0006 0.001 0.002
Mycobacterium tuberculosis Conserved protein 0.0053 0.0867 0.1402
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0051 0.0827 0.1627
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0006 0.001 0.002
Loa Loa (eye worm) cytochrome P450 0.001 0.0069 0.0189
Echinococcus granulosus beta LACTamase domain containing family member 0.0053 0.0867 0.1705
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0159 0.2827 0.4611
Giardia lamblia Fructose-bisphosphate aldolase 0.0245 0.4427 1
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.014
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0046 0.0057
Trypanosoma brucei protein kinase, putative 0.004 0.0641 0.2518
Schistosoma mansoni thioredoxin peroxidase 3 0.0142 0.2515 0.4947
Trichomonas vaginalis penicillin-binding protein, putative 0.0053 0.0867 0.1939
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0006 0.0011 0.0002
Echinococcus granulosus GPCR family 2 0.0054 0.0885 0.1742
Mycobacterium leprae POSSIBLE THIOREDOXIN PROTEIN (THIOL-DISULFIDE INTERCHANGE PROTEIN) 0.0033 0.0497 0.1547
Mycobacterium ulcerans bacterioferritin comigratory protein Bcp 0.0033 0.0497 0.2319
Schistosoma mansoni lipoxygenase 0.0046 0.0749 0.1473
Trichomonas vaginalis cyclin B, putative 0.0021 0.0289 0.063
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0053 0.0867 0.1402
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0245 0.4427 1
Schistosoma mansoni lipoxygenase 0.0017 0.0198 0.039
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.004 0.0641 0.2518
Loa Loa (eye worm) dehydrogenase 0.0008 0.0046 0.0114
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0011 0.009 0.0177
Schistosoma mansoni polycystin 1-related 0.0017 0.0198 0.039
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.004 0.0641 0.2518
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0024 0.0338 0.1308
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0024 0.0338 0.0665
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0053 0.0867 0.2747
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.001 0.0069 0.0133
Trichomonas vaginalis set domain proteins, putative 0.0199 0.3575 0.8072
Echinococcus granulosus cyclin B3 1 0.0021 0.0289 0.0568
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0008 0.0046 0.0057
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.012 0.2107 0.3433
Mycobacterium tuberculosis Possible oxidoreductase 0.0008 0.0046 0.0057
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Brugia malayi Cytochrome P450 family protein 0.001 0.0069 0.0189
Onchocerca volvulus 0.0008 0.0046 0.01
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Schistosoma mansoni cpg binding protein 0.0021 0.0278 0.0546
Mycobacterium ulcerans lipoprotein DsbF 0.0033 0.0497 0.2319
Onchocerca volvulus 0.0026 0.0367 0.1002
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0046 0.0079
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0008 0.0046 0.014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0108 0.0219
Echinococcus granulosus Peroxiredoxin 2 0.0142 0.2515 0.4947
Trichomonas vaginalis CAMK family protein kinase 0.008 0.1365 0.3066
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0066 0.1122 0.2517
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.001 0.0069 0.0095
Loa Loa (eye worm) hypothetical protein 0.0008 0.0046 0.0114
Loa Loa (eye worm) hypothetical protein 0.0045 0.0717 0.2268
Echinococcus granulosus cyclins 0.0021 0.0289 0.0568
Loa Loa (eye worm) hypothetical protein 0.0053 0.0867 0.2747
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0046 0.0079
Entamoeba histolytica peroxiredoxin 0.0142 0.2515 0.567
Loa Loa (eye worm) hypothetical protein 0.0017 0.0198 0.0604
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0046 0.014
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0337 0.6118 1
Schistosoma mansoni hypothetical protein 0.001 0.0069 0.0135
Wolbachia endosymbiont of Brugia malayi thiol-disulfide isomerase 0.0033 0.0497 0.1942
Plasmodium falciparum steroid dehydrogenase, putative 0.0008 0.0046 0.014
Trichomonas vaginalis cyclin B3, putative 0.0021 0.0289 0.063
Schistosoma mansoni retinoic acid receptor RXR 0.0006 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.0006 0.0011 0.0002
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0008 0.0046 0.0079
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0024 0.0338 0.0536
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0043 0.0683 0.1343
Brugia malayi MAP kinase sur-1 0.004 0.0641 0.2023
Schistosoma mansoni hypothetical protein 0.0015 0.0172 0.0339
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0008 0.0046 0.014
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Echinococcus granulosus FTZ F1 alpha 0.0006 0.001 0.002
Brugia malayi beta-lactamase 0.0053 0.0867 0.2747
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0006 0.0011 0.0021
Toxoplasma gondii carbonyl reductase 1, putative 0.0008 0.0046 0.014
Leishmania major lanosterol 14-alpha-demethylase, putative 0.001 0.0069 0.0232
Trichomonas vaginalis steroid dehydrogenase, putative 0.0008 0.0046 0.0079
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0008 0.0046 0.01
Echinococcus granulosus cyclins 0.0021 0.0289 0.0568
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.008 0.1365 0.4343
Echinococcus granulosus WW domain containing oxidoreductase 0.0008 0.0046 0.009
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0167
Brugia malayi dehydrogenases, short chain protein 9 0.0008 0.0046 0.0114
Leishmania major hypothetical protein, conserved 0.0008 0.0046 0.014
Echinococcus granulosus geminin 0.0223 0.4014 0.7897
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0006 0.001 0.002
Leishmania major phosphopantetheinyl transferase-like protein 0.002 0.0255 0.0976
Toxoplasma gondii thioredoxin reductase 0.007 0.1179 0.4665
Onchocerca volvulus 0.0035 0.054 0.1488
Echinococcus granulosus glutamate synthase 0.0006 0.0011 0.0021
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Trypanosoma cruzi cytochrome P450, putative 0.001 0.0069 0.0232
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0069 0.0133
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0008 0.0046 0.009
Giardia lamblia Hypothetical protein 0.0008 0.0046 0.0079
Onchocerca volvulus 0.0017 0.0198 0.0528
Loa Loa (eye worm) oxidoreductase 0.0008 0.0046 0.0114
Trichomonas vaginalis D-aminoacylase, putative 0.0053 0.0867 0.1939
Echinococcus granulosus oxidoreductase 0.0008 0.0046 0.009
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.004 0.0641 0.2518
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.001 0.0069 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0069 0.0133
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0006 0.001 0.001
Brugia malayi Valyl-tRNA synthetase 0.001 0.0069 0.019
Echinococcus granulosus chromobox protein 1 0.0058 0.0973 0.1915
Plasmodium vivax merozoite capping protein 1, putative 0.0033 0.0497 0.1942
Mycobacterium tuberculosis Probable oxidoreductase 0.0176 0.3154 0.5147
Plasmodium falciparum thioredoxin peroxidase 2 0.0142 0.2515 1
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0008 0.0046 0.0167
Loa Loa (eye worm) hypothetical protein 0.0077 0.1318 0.4193
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.001 0.0069 0.0277
Entamoeba histolytica peroxiredoxin 0.0142 0.2515 0.567
Echinococcus granulosus intermediate filament protein 0.0035 0.054 0.1063
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0046 0.0079
Loa Loa (eye worm) hypothetical protein 0.0053 0.0867 0.2747
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0544 0.1208
Loa Loa (eye worm) intermediate filament protein 0.0035 0.054 0.17
Mycobacterium tuberculosis Probable peroxidoxin BcpB 0.0033 0.0497 0.0796
Mycobacterium ulcerans esterase/lipase LipP 0.0053 0.0867 0.4083
Echinococcus multilocularis cyclins 0.0021 0.0289 0.0289
Schistosoma mansoni sulfide quinone reductase 0.0006 0.0011 0.0021
Brugia malayi CHD4 protein 0.0011 0.009 0.0257
Trichomonas vaginalis CMGC family protein kinase 0.004 0.0641 0.1427
Giardia lamblia G2/mitotic-specific cyclin B 0.0021 0.0289 0.063
Entamoeba histolytica cyclin family protein 0.0021 0.0289 0.063
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.002 0.0255 0.0976
Mycobacterium tuberculosis Possible thioredoxin protein (thiol-disulfide interchange protein) 0.0033 0.0497 0.0796
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0046 0.0079
Trichomonas vaginalis chromobox protein, putative 0.001 0.0069 0.0133
Loa Loa (eye worm) oxidoreductase 0.0008 0.0046 0.0114
Mycobacterium ulcerans alkyl hydroperoxide reductase C protein AhpC 0.0097 0.169 0.8007
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0053 0.0867 0.1402
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.0046 0.0167
Wolbachia endosymbiont of Brugia malayi peroxiredoxin 0.0033 0.0497 0.1942
Schistosoma mansoni hypothetical protein 0.0054 0.0885 0.1742
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0008 0.0046 0.014
Echinococcus multilocularis cyclins 0.0021 0.0289 0.0289
Giardia lamblia NADH oxidase lateral transfer candidate 0.0024 0.0338 0.0741
Schistosoma mansoni serine/threonine protein kinase 0.008 0.1365 0.2685
Plasmodium falciparum cyclin 0.0021 0.0289 0.1111
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0152 0.032
Onchocerca volvulus 0.0008 0.0046 0.01
Plasmodium falciparum 1-cys peroxiredoxin 0.0142 0.2515 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0338 0.1308
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0046 0.014
Plasmodium falciparum thioredoxin peroxidase 1 0.0142 0.2515 1
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0046 0.009
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.054 0.1063
Mycobacterium ulcerans ketoacyl reductase 0.0008 0.0046 0.0167
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0053 0.0867 0.1705
Loa Loa (eye worm) hypothetical protein 0.0066 0.1122 0.3566
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0338 0.1308
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0046 0.009
Echinococcus multilocularis chromobox protein 1 0.0058 0.0973 0.0973
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0245 0.4427 1
Mycobacterium tuberculosis Conserved protein 0.0053 0.0867 0.1402
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0069 0.0133
Loa Loa (eye worm) oxidoreductase 0.0008 0.0046 0.0114
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0046 0.0079
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0006 0.001 0.002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.001 0.0069 0.0277
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0176 0.3154 1
Echinococcus multilocularis GPCR, family 2 0.0054 0.0885 0.0885
Loa Loa (eye worm) hypothetical protein 0.0026 0.0367 0.1146
Brugia malayi Thioredoxin reductase 0.007 0.1179 0.3747
Schistosoma mansoni peroxiredoxins prx-1 prx-2 prx-3 0.0033 0.0497 0.0978
Entamoeba histolytica cyclin, putative 0.0021 0.0289 0.063
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.002 0.0255 0.0976
Loa Loa (eye worm) hypothetical protein 0.001 0.0069 0.019
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0008 0.0046 0.014
Trichomonas vaginalis peroxiredoxins, prx-1, prx-2, prx-3, putative 0.0142 0.2515 0.567
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0024 0.0338 0.1308
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.001 0.0069 0.0277
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0024 0.0338 0.1562
Brugia malayi hypothetical protein 0.0033 0.0497 0.1561
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0101 0.1756 0.1756
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.002 0.0255 0.0976
Mycobacterium tuberculosis Probable reductase 0.0159 0.2827 0.4611
Plasmodium vivax thioredoxin peroxidase 1, putative 0.0142 0.2515 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.009 0.0177
Onchocerca volvulus 0.0008 0.0046 0.01
Echinococcus multilocularis retinol dehydrogenase 13 0.0008 0.0046 0.0046
Echinococcus multilocularis Chromo domain 0.001 0.0069 0.0069
Giardia lamblia Reductase, putative 0.0008 0.0046 0.0079
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0046 0.009
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.001 0.0069 0.0095
Echinococcus multilocularis glutamate synthase 0.0006 0.0011 0.0011
Leishmania major short chain dehydrogenase-like protein 0.0008 0.0046 0.014
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0008 0.0046 0.0057
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0008 0.0046 0.014
Loa Loa (eye worm) latrophilin receptor protein 2 0.0054 0.0885 0.2806
Toxoplasma gondii LsmAD domain-containing protein 0.0034 0.0516 0.2018
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0008 0.0046 0.009
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.001 0.0069 0.0232
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0046 0.014
Entamoeba histolytica 1-Cys peroxiredoxin, putative 0.0077 0.1322 0.2969
Leishmania major tryparedoxin peroxidase 0.0142 0.2515 1
Onchocerca volvulus 0.0008 0.0046 0.01
Trichomonas vaginalis cyclin B, putative 0.0021 0.0289 0.063
Echinococcus granulosus thioredoxin dependent peroxide reductase 0.0142 0.2515 0.4947
Mycobacterium ulcerans hypothetical protein 0.0053 0.0867 0.4083
Loa Loa (eye worm) oxidoreductase 0.0008 0.0046 0.0114
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0008 0.0046 0.014
Trypanosoma cruzi trypanothione reductase, putative 0.0024 0.0338 0.1308
Echinococcus multilocularis Polycystic kidney disease protein 0.0017 0.0198 0.0198
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.001 0.0069 0.0277
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0021 0.0289 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0321 0.0704
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0046 0.0167
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0008 0.0046 0.0167
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0021 0.0289 0.1111
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0024 0.0338 0.1308
Giardia lamblia Short-chain dehydrogenase, putative 0.0008 0.0046 0.0079
Mycobacterium ulcerans beta-lactamase 0.0053 0.0867 0.4083
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0018 0.022 0.0673
Loa Loa (eye worm) hypothetical protein 0.0098 0.1709 0.5445
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0008 0.0046 0.009
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0046 0.014
Echinococcus multilocularis cyclins 0.0021 0.0289 0.0289
Onchocerca volvulus 0.007 0.1182 0.3288
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0101 0.1756 0.3455
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.001 0.0069 0.0277
Mycobacterium ulcerans peroxiredoxin AhpE 0.0097 0.169 0.8007
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0017 0.0205 0.0404
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0008 0.0046 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.001 0.0069 0.0095
Mycobacterium tuberculosis Probable oxidoreductase 0.0008 0.0046 0.0057
Giardia lamblia Hypothetical protein 0.0021 0.0289 0.063
Trypanosoma brucei peroxidoxin 0.0142 0.2515 1
Schistosoma mansoni rab6-interacting 0.0017 0.0198 0.039
Loa Loa (eye worm) hypothetical protein 0.0035 0.054 0.17
Schistosoma mansoni hypothetical protein 0.0281 0.5083 1
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0008 0.0046 0.0079
Mycobacterium leprae Probable lipase LipE 0.0053 0.0867 0.2724
Trichomonas vaginalis chromobox protein, putative 0.001 0.0069 0.0133
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.0069 0.0189
Loa Loa (eye worm) hypothetical protein 0.0053 0.0867 0.2747
Leishmania major tryparedoxin peroxidase 0.0142 0.2515 1
Echinococcus multilocularis retinol dehydrogenase 11 0.0008 0.0046 0.0046
Echinococcus multilocularis lipoxygenase domain containing protein 0.0017 0.0198 0.0198
Echinococcus multilocularis thioredoxin peroxidase 0.0142 0.2515 0.2515
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0006 0.0011 0.0011
Echinococcus multilocularis cyclin B 0.0021 0.0289 0.0289
Trichomonas vaginalis cyclins, putative 0.0021 0.0289 0.063
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0006 0.001 0.001
Brugia malayi Pre-SET motif family protein 0.0025 0.0364 0.1133
Plasmodium falciparum peroxiredoxin 0.0033 0.0497 0.1942
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0245 0.4427 1
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0008 0.0046 0.014
Toxoplasma gondii oxidoreductase, putative 0.0008 0.0046 0.014
Schistosoma mansoni sulfide quinone reductase 0.0006 0.0011 0.0021
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0011 0.009 0.009
Onchocerca volvulus Serine\/threonine kinase homolog 0.008 0.1365 0.3799
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Schistosoma mansoni cpg binding protein 0.002 0.0257 0.0505
Echinococcus multilocularis chromobox protein 1 0.0058 0.0973 0.0973
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0545 0.1714
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0008 0.0046 0.014
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0006 0.0011 0.0011
Echinococcus multilocularis FTZ F1 alpha 0.0006 0.001 0.001
Mycobacterium leprae conserved hypothetical protein 0.0053 0.0867 0.2724
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.001 0.0069 0.0277
Trichomonas vaginalis CMGC family protein kinase 0.004 0.0641 0.1427
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.001 0.0069 0.0277
Trypanosoma cruzi tryparedoxin peroxidase, putative 0.0142 0.2515 1
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.001 0.0069 0.0277
Trypanosoma cruzi tryparedoxin peroxidase, putative 0.0142 0.2515 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.004 0.0641 0.2023
Entamoeba histolytica hypothetical protein 0.0008 0.0046 0.0079
Loa Loa (eye worm) oxidoreductase 0.0008 0.0046 0.0114
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0159 0.2827 0.8958
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0042 0.0674 0.2127
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.001 0.0069 0.0095
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0046 0.009
Schistosoma mansoni lamin 0.0035 0.054 0.1063
Mycobacterium leprae putative cytochrome p450 0.001 0.0069 0.0185
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Schistosoma mansoni thioredoxin peroxidase 0.0033 0.0497 0.0978
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0046 0.0167
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.001 0.0069 0.0095
Trypanosoma brucei PAB1-binding protein , putative 0.0034 0.0516 0.2018
Loa Loa (eye worm) hypothetical protein 0.0021 0.0289 0.0894
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0176 0.3154 0.5147
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0008 0.0046 0.0079
Mycobacterium tuberculosis Probable dehydrogenase 0.0008 0.0046 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0114 0.0233
Schistosoma mansoni hypothetical protein 0.001 0.0069 0.0136
Plasmodium falciparum ataxin-2 like protein, putative 0.0034 0.0516 0.2018
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0015 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.001 0.0069 0.019
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0053 0.0867 0.2747
Trichomonas vaginalis cyclin B, putative 0.0021 0.0289 0.063
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0008 0.0046 0.009
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.014
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0006 0.0011 0.0011
Brugia malayi Dehydrogenases, short chain protein 30 0.0008 0.0046 0.0114
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0046 0.014
Schistosoma mansoni hypothetical protein 0.0017 0.0198 0.039
Trichomonas vaginalis penicillin-binding protein, putative 0.0053 0.0867 0.1939
Trichomonas vaginalis hypothetical protein 0.001 0.0069 0.0133
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0008 0.0046 0.0057
Trypanosoma cruzi PAB1-binding protein , putative 0.0034 0.0516 0.2018
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0046 0.009
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0098 0.1709 0.4764
Mycobacterium ulcerans membrane-anchored thioredoxin-like protein 0.0033 0.0497 0.2319
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0008 0.0046 0.0046
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0046 0.009
Brugia malayi hypothetical protein 0.001 0.0069 0.019
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.001 0.0069 0.0234
Echinococcus multilocularis L aminoadipate semialdehyde 0.007 0.1182 0.1182
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0051 0.0827 0.0827
Giardia lamblia Peroxiredoxin 1 0.0142 0.2515 0.567
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.001 0.0069 0.0095
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0152 0.032
Leishmania major hypothetical protein, conserved 0.0053 0.0867 0.3419
Trypanosoma cruzi cytochrome P450, putative 0.001 0.0069 0.0232
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0008 0.0046 0.014
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.001 0.0069 0.0277
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0364 0.0715
Trichomonas vaginalis chromobox protein, putative 0.001 0.0069 0.0133
Onchocerca volvulus 0.0053 0.0867 0.2403
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0069 0.0133
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0046 0.0114
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0008 0.0046 0.014
Loa Loa (eye worm) CYP4Cod1 0.001 0.0069 0.0189

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 5 uM Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin E ChEMBL. No reference
IC50 (binding) = 5 uM Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin E ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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