Detailed information for compound 1551855

Basic information

Technical information
  • TDR Targets ID: 1551855
  • Name: [(2R,3S,6S)-3-acetyloxy-6-[2-(4-tert-butylphe nyl)ethynyl]-3,6-dihydro-2H-pyran-2-yl]methyl acetate
  • MW: 370.439 | Formula: C22H26O5
  • H donors: 0 H acceptors: 2 LogP: 3.95 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)OC[C@H]1O[C@H](C#Cc2ccc(cc2)C(C)(C)C)C=C[C@@H]1OC(=O)C
  • InChi: 1S/C22H26O5/c1-15(23)25-14-21-20(26-16(2)24)13-12-19(27-21)11-8-17-6-9-18(10-7-17)22(3,4)5/h6-7,9-10,12-13,19-21H,14H2,1-5H3/t19-,20+,21-/m1/s1
  • InChiKey: OLDTWKJGJZXYRD-QHAWAJNXSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [(2R,3S,6S)-3-acetoxy-6-[2-(4-tert-butylphenyl)ethynyl]-3,6-dihydro-2H-pyran-2-yl]methyl acetate
  • acetic acid [(2R,3S,6S)-3-acetoxy-6-[2-(4-tert-butylphenyl)ethynyl]-3,6-dihydro-2H-pyran-2-yl]methyl ester
  • [(2R,3S,6S)-3-acetyloxy-6-[2-(4-tert-butylphenyl)ethynyl]-3,6-dihydro-2H-pyran-2-yl]methyl ethanoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Beta tubulin 0.0343 0.1474 0.5624
Echinococcus multilocularis segment polarity protein dishevelled 0.0016 0.0002 0.0002
Toxoplasma gondii hypothetical protein 0.0395 0.1707 0.5397
Entamoeba histolytica hypothetical protein 0.0276 0.1174 0.3711
Echinococcus granulosus Nuclear hormone receptor HR96 0.0046 0.0138 0.022
Echinococcus multilocularis protein jagged 1 0.0076 0.0273 0.0273
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0115 0.0449 0.1418
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0021 0.0024 0.0039
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0083 0.0132
Schistosoma mansoni alpha tubulin 0.0281 0.1195 0.1904
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Leishmania major 4-coumarate:coa ligase-like protein 0.0019 0.0014 0.0044
Brugia malayi MH1 domain containing protein 0.0019 0.0014 0.0025
Trypanosoma cruzi cytochrome P450, putative 0.009 0.0334 0.1056
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0082 0.0258
Onchocerca volvulus 0.0353 0.1519 0.4803
Echinococcus multilocularis tubulin beta 1 chain 0.0343 0.1474 0.1474
Schistosoma mansoni regulator of G protein signaling 0.0016 0.0002 0.0003
Entamoeba histolytica DNA topoisomerase III, putative 0.0063 0.0212 0.067
Trypanosoma cruzi DNA topoisomerase III, putative 0.0063 0.0212 0.067
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0138 0.022
Trypanosoma brucei hexokinase 0.0718 0.3163 1
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0241 0.1013 0.3203
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0191 0.0672
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0087 0.032 0.1009
Echinococcus multilocularis GPCR, family 2 0.0056 0.0182 0.0182
Loa Loa (eye worm) glutaminase 0.0195 0.0809 0.1421
Onchocerca volvulus Putative organic anion transporter 0.0022 0.0029 0.0093
Onchocerca volvulus 0.0022 0.0029 0.0093
Loa Loa (eye worm) alpha-tubulin 0.0281 0.1195 0.2101
Echinococcus granulosus alpha tubulin 0.0281 0.1195 0.1904
Entamoeba histolytica DNA topoisomerase II, putative 0.0632 0.2774 0.8771
Trypanosoma cruzi hexokinase, putative 0.0718 0.3163 1
Echinococcus granulosus Tubulin alpha 1 chain 0.0281 0.1195 0.1904
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0034 0.0082 0.0232
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0026 0.0048 0.0077
Loa Loa (eye worm) BEN-1 protein 0.0343 0.1474 0.2592
Echinococcus multilocularis neuropeptide receptor A26 0.0948 0.4201 0.4201
Leishmania major mitochondrial DNA topoisomerase II 0.0651 0.2862 0.9048
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0079 0.0286 0.0455
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Onchocerca volvulus Huntingtin homolog 0.0139 0.0554 0.1751
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0038 0.0099 0.0433
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0016 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0333 0.1173
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0046 0.0137 0.0481
Plasmodium vivax heat shock protein 86, putative 0.0034 0.0082 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0169
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Echinococcus multilocularis neurogenic locus notch protein 4 0.0076 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0052
Echinococcus granulosus pyruvate kinase 0.0027 0.0049 0.0078
Echinococcus granulosus Nuclear hormone receptor HR96 0.0046 0.0138 0.022
Loa Loa (eye worm) latrophilin receptor protein 2 0.0056 0.0182 0.0319
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.009 0.0333 0.1052
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0038 0.0099 0.0433
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Brugia malayi EGF-like domain containing protein 0.0076 0.0273 0.048
Echinococcus granulosus caspase 2 0.0021 0.0024 0.0039
Trichomonas vaginalis tubulin alpha chain, putative 0.0343 0.1474 0.5196
Giardia lamblia High cysteine protein 0.0076 0.0273 0.104
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0028
Trypanosoma cruzi DNA topoisomerase III, putative 0.0063 0.0212 0.067
Echinococcus multilocularis Niemann Pick C1 protein 0.0318 0.1364 0.1364
Entamoeba histolytica protein kinase rad3, putative 0.0016 0.0003 0.0009
Loa Loa (eye worm) Smad1 0.0034 0.0083 0.0146
Brugia malayi Nuclear hormone receptor E75 0.0046 0.0138 0.0242
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0038 0.0099 0.0433
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0058 0.0192 0.0676
Echinococcus granulosus tubulin beta 4A class IVa 0.0343 0.1474 0.2348
Loa Loa (eye worm) hypothetical protein 0.0058 0.019 0.0334
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0059 0.0194 0.0194
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0281 0.1195 0.4213
Brugia malayi Latrophilin receptor protein 2 0.0056 0.0182 0.0319
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0046 0.0138 0.0242
Trypanosoma cruzi epsilon tubulin, putative 0.0206 0.0859 0.2716
Schistosoma mansoni cellular tumor antigen P53 0.0056 0.0181 0.0289
Entamoeba histolytica tubulin family protein 0.0343 0.1474 0.4661
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0063 0.0212 0.0338
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0063 0.0212 0.0338
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0041 0.0114 0.0359
Brugia malayi beta-tubulin, identical 0.0343 0.1474 0.2592
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0021 0.0024 0.0076
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0104 0.0399 0.0635
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.0097 0.017
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0064 0.0217 0.0685
Echinococcus multilocularis isocitrate dehydrogenase 0.0079 0.0287 0.0287
Onchocerca volvulus Pyruvate kinase homolog 0.0027 0.0049 0.0155
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0034 0.0082 0.0258
Leishmania major cytochrome p450-like protein 0.0038 0.0099 0.0311
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0058 0.0192 0.0676
Plasmodium falciparum heat shock protein 90 0.0034 0.0082 0.0259
Schistosoma mansoni hypothetical protein 0.0076 0.0273 0.0435
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0038 0.0099 0.0433
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Trypanosoma brucei alpha tubulin 0.0281 0.1195 0.3779
Plasmodium falciparum hexokinase 0.0718 0.3163 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0026 0.0048 0.0151
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.046 0.2001 0.6326
Loa Loa (eye worm) hypothetical protein 0.0177 0.0727 0.1278
Trichomonas vaginalis DNA polymerase eta, putative 0.0037 0.0097 0.034
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Loa Loa (eye worm) hexokinase 0.0222 0.093 0.1634
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0191 0.0792 0.1391
Plasmodium falciparum DNA topoisomerase 3, putative 0.0063 0.0212 0.0671
Onchocerca volvulus 0.0063 0.0212 0.0671
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0037 0.0097 0.0424
Brugia malayi Bloom's syndrome protein homolog 0.0016 0 0.0001
Echinococcus multilocularis lamin 0.0132 0.0523 0.0523
Echinococcus multilocularis tubulin alpha chain 0.0281 0.1195 0.1195
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0079 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0052
Mycobacterium leprae Probable two component sensor kinase MprB 0.0034 0.0082 0.1165
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Schistosoma mansoni dep domain containing protein 0.0016 0.0002 0.0003
Echinococcus granulosus beta tubulin 0.0343 0.1474 0.2348
Echinococcus multilocularis sterol regulatory element binding protein 0.0096 0.036 0.036
Schistosoma mansoni microtubule-associated protein tau 0.141 0.628 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0016 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0104 0.0399 0.0701
Echinococcus granulosus mitogen activated protein kinase 3 0.0115 0.0449 0.0715
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Loa Loa (eye worm) cytochrome P450 family protein 0.009 0.0334 0.0588
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0085
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0019 0.0016 0.0028
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0063 0.0212 0.0747
Echinococcus granulosus beta tubulin 0.0343 0.1474 0.2348
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0034 0.0082 0.0288
Onchocerca volvulus 0.0132 0.0523 0.1652
Schistosoma mansoni survival motor neuron protein 0.0261 0.1104 0.1758
Entamoeba histolytica tubulin family protein 0.0343 0.1474 0.4661
Mycobacterium tuberculosis Probable two component sensor kinase 0.0034 0.0082 0.0348
Echinococcus granulosus tubulin gamma 1 chain 0.0206 0.0859 0.1368
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0026 0.0048 0.0077
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0049 0.0149 0.0262
Schistosoma mansoni caspase-7 (C14 family) 0.0079 0.0286 0.0455
Entamoeba histolytica hexokinase 2 0.0718 0.3163 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.0399 0.0701
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0395 0.1707 0.3001
Loa Loa (eye worm) hypothetical protein 0.0371 0.1601 0.2814
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0016 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0016 0.0016
Brugia malayi Animal haem peroxidase family protein 0.059 0.2588 0.455
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0263 0.0924
Plasmodium vivax tubulin beta chain, putative 0.0343 0.1474 0.4662
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0034 0.0082 0.0348
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0104 0.0399 0.0635
Echinococcus multilocularis Tubulin beta 2C chain 0.0343 0.1474 0.1474
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Loa Loa (eye worm) hypothetical protein 0.0281 0.1195 0.2101
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0087 0.032 0.1009
Brugia malayi conserved hypotetical protein 0.0046 0.0138 0.0242
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0038 0.0099 0.0433
Echinococcus multilocularis neurogenic locus protein delta 0.0076 0.0273 0.0273
Brugia malayi sodium-independent organic anion transporter family protein 0.0022 0.0029 0.0052
Trypanosoma cruzi tubulin gamma chain 0.0206 0.0859 0.2716
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0004
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0039 0.0104 0.033
Echinococcus granulosus neurogenic locus notch protein 4 0.0076 0.0273 0.0435
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0016 0.0025
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0058 0.0192 0.0606
Leishmania major protein kinase, putative 0.0072 0.0254 0.08
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0083 0.0146
Loa Loa (eye worm) tubulin beta-4 chain 0.0343 0.1474 0.2592
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0059 0.0197 0.0621
Echinococcus granulosus FTZ F1 alpha 0.0104 0.0399 0.0635
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0016 0.0002 0.0007
Echinococcus granulosus tubulin alpha chain 0.0281 0.1195 0.1904
Echinococcus multilocularis Tubulin alpha 1 chain 0.0281 0.1195 0.1195
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0046 0.0138 0.0138
Entamoeba histolytica tubulin alpha-1 chain 0.0281 0.1195 0.3779
Trichomonas vaginalis pyruvate kinase, putative 0.0027 0.0049 0.0171
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.009 0.0332 0.0529
Loa Loa (eye worm) hypothetical protein 0.0046 0.0138 0.0242
Leishmania major 4-coumarate:coa ligase-like protein 0.0019 0.0014 0.0044
Brugia malayi chromobox protein homolog 3 0.0028 0.0055 0.0096
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0044 0.0127 0.0203
Schistosoma mansoni endoplasmin 0.0034 0.0082 0.0131
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0056 0.0182 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0192 0.0676
Loa Loa (eye worm) tubulin beta chain 0.009 0.0333 0.0585
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0038 0.0099 0.0311
Brugia malayi nuclear receptor NHR-88 0.0046 0.0138 0.0242
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0076 0.0273 0.048
Echinococcus multilocularis pyruvate kinase 0.0021 0.0024 0.0024
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0064 0.0217 0.0685
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0016 0.0002 0.0003
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0104 0.155
Brugia malayi hypothetical protein 0.0124 0.0486 0.0855
Loa Loa (eye worm) intermediate filament protein 0.0132 0.0523 0.0919
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0026 0.0048 0.0182
Brugia malayi alpha-tubulin 0.0281 0.1195 0.2101
Brugia malayi regulator of G-protein signaling egl-10 0.0016 0.0002 0.0004
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0037 0.0097 0.0305
Plasmodium vivax endoplasmin, putative 0.0034 0.0082 0.0259
Toxoplasma gondii DNA topoisomerase family protein 0.0063 0.0212 0.067
Brugia malayi Intermediate filament tail domain containing protein 0.0132 0.0523 0.0919
Brugia malayi nuclear receptor NHR-67 0.0046 0.0138 0.0242
Echinococcus multilocularis regulator of G protein signaling 7 0.0016 0.0002 0.0002
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0069 0.0239 0.1154
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0038 0.0099 0.0433
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0569 0.2491 0.7876
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0024 0.0085
Trypanosoma cruzi PAB1-binding protein , putative 0.0124 0.0486 0.1536
Trypanosoma cruzi metacaspase, putative 0.0021 0.0024 0.0076
Brugia malayi Pax transcription factor protein 2 0.0272 0.1156 0.2032
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Trypanosoma brucei epsilon tubulin 0.0206 0.0859 0.2716
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0162 0.0572
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0038 0.0099 0.0433
Schistosoma mansoni hypothetical protein 0.1256 0.5586 0.8895
Schistosoma mansoni hypothetical protein 0.0178 0.0731 0.1163
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0004
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.0016 0.0016
Trypanosoma brucei hexokinase 0.0718 0.3163 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0138 0.0242
Loa Loa (eye worm) hypothetical protein 0.0058 0.019 0.0334
Echinococcus multilocularis hexokinase 0.0718 0.3163 0.3163
Echinococcus granulosus microtubule associated protein 2 0.141 0.628 1
Brugia malayi Tubulin alpha-2 chain 0.0281 0.1195 0.2101
Loa Loa (eye worm) hypothetical protein 0.0058 0.019 0.0334
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0043 0.0121 0.0213
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0037 0.0119
Schistosoma mansoni glutaminase 0.0195 0.0809 0.1288
Echinococcus granulosus lamin 0.0132 0.0523 0.0832
Echinococcus multilocularis Smad4 0.0034 0.0083 0.0083
Trypanosoma brucei alpha tubulin, putative 0.0117 0.0456 0.1439
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0192 0.0676
Loa Loa (eye worm) hypothetical protein 0.0524 0.2291 0.4027
Trypanosoma cruzi metacaspase, putative 0.0021 0.0024 0.0076
Echinococcus granulosus tubulin subunit beta 0.0343 0.1474 0.2348
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0038 0.0099 0.0311
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0064 0.0217 0.0345
Trypanosoma brucei metacaspase MCA2 0.0021 0.0024 0.0076
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0038 0.0099 0.0433
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0038 0.0099 0.0433
Loa Loa (eye worm) tubulin alpha 2 0.0075 0.0265 0.0466
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0079 0.0287 0.0905
Trypanosoma cruzi pyruvate kinase 2, putative 0.0027 0.0049 0.0154
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0026 0.0048 0.0077
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0366 0.1576 0.4981
Trypanosoma cruzi heat shock protein 90, putative 0.0034 0.0082 0.0258
Trichomonas vaginalis pyruvate kinase, putative 0.0027 0.0049 0.0171
Loa Loa (eye worm) hypothetical protein 0.0037 0.0097 0.017
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0048 0.0151
Schistosoma mansoni dishevelled 0.0016 0.0002 0.0003
Echinococcus multilocularis tubulin alpha 0.0206 0.0859 0.0859
Loa Loa (eye worm) Notch2 0.0076 0.0273 0.048
Echinococcus multilocularis caspase 0.0079 0.0286 0.0286
Echinococcus multilocularis geminin 0.1256 0.5586 0.5586
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.006 0.0199 0.035
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0148 0.0595 0.1881
Trichomonas vaginalis tubulin epsilon chain, putative 0.009 0.0333 0.1173
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0167 0.0265
Trichomonas vaginalis tubulin alpha chain, putative 0.0117 0.0456 0.1604
Plasmodium vivax pyruvate kinase, putative 0.0027 0.0049 0.0155
Toxoplasma gondii heat shock protein HSP90 0.0034 0.0082 0.0258
Loa Loa (eye worm) hypothetical protein 0.0058 0.019 0.0334
Brugia malayi Calcitonin receptor-like protein seb-1 0.0177 0.0727 0.1278
Brugia malayi Calcium binding EGF domain containing protein 0.0076 0.0273 0.048
Leishmania major DNA topoisomerase ii 0.0569 0.2491 0.7876
Echinococcus multilocularis regulator of G protein signaling 7 0.0016 0.0002 0.0002
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0038 0.0099 0.0311
Loa Loa (eye worm) hypothetical protein 0.0117 0.0457 0.0803
Echinococcus granulosus jun protein 0.0095 0.0357 0.0569
Schistosoma mansoni hypothetical protein 0.0092 0.0344 0.0549
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0097 0.0424
Brugia malayi Pre-SET motif family protein 0.0081 0.0296 0.052
Echinococcus granulosus histone lysine methyltransferase setb 0.0081 0.0296 0.0471
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.009 0.0334 0.1646
Echinococcus multilocularis tubulin alpha chain 0.0281 0.1195 0.1195
Loa Loa (eye worm) nuclear receptor NHR-67 0.0046 0.0138 0.0242
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0016 0.0002 0.0004
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Loa Loa (eye worm) pyruvate kinase-PB 0.0019 0.0013 0.0022
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0079 0.0287 0.0287
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0016 0 0.0001
Entamoeba histolytica DNA topoisomerase III, putative 0.0063 0.0212 0.067
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0014 0.0025
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0058 0.019 0.0303
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0104 0.0399 0.0701
Loa Loa (eye worm) hypothetical protein 0.0124 0.0486 0.0855
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0115 0.0362
Trypanosoma brucei alpha tubulin 0.0281 0.1195 0.3779
Trypanosoma brucei metacaspase 0.0021 0.0024 0.0076
Brugia malayi Calcium binding EGF domain containing protein 0.0076 0.0273 0.048
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0038 0.0099 0.0433
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0104 0.0399 0.0701
Brugia malayi nuclear hormone receptor family member nhr-6 0.0046 0.0138 0.0242
Brugia malayi Tubulin beta chain 0.0117 0.0456 0.0801
Echinococcus granulosus tubulin alpha chain 0.0281 0.1195 0.1904
Loa Loa (eye worm) hypothetical protein 0.0164 0.0669 0.1176
Loa Loa (eye worm) hexokinase 0.0718 0.3163 0.5559
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0015
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0037 0.0097 0.0097
Trypanosoma brucei unspecified product 0.0026 0.0045 0.0141
Brugia malayi latrophilin 2 splice variant baaae 0.0121 0.0475 0.0835
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0056 0.0182 0.0319
Brugia malayi tubulin alpha-2 chain 0.0281 0.1195 0.2101
Brugia malayi hexokinase type II 0.0228 0.0957 0.1683
Onchocerca volvulus 0.0076 0.0273 0.0863
Loa Loa (eye worm) hypothetical protein 0.0132 0.0523 0.0919
Leishmania major cytochrome p450-like protein 0.0038 0.0099 0.0311
Brugia malayi steroid hormone receptor 0.0104 0.0399 0.0701
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0063 0.0212 0.0338
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0038 0.0099 0.0433
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0039 0.0104 0.0183
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0024 0.0077
Schistosoma mansoni thyroid hormone receptor 0.0104 0.0399 0.0635
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0034 0.0082 0.0348
Leishmania major pyruvate kinase 0.0027 0.0049 0.0154
Leishmania major gamma-tubulin 0.0206 0.0859 0.2716
Echinococcus granulosus intermediate filament protein 0.0132 0.0523 0.0832
Echinococcus granulosus neural cadherin 0.0076 0.0273 0.0435
Entamoeba histolytica hypothetical protein 0.0016 0.0003 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0296 0.0471
Echinococcus granulosus ecdysone induced protein 78C 0.0104 0.0399 0.0635
Schistosoma mansoni terminal deoxycytidyl transferase 0.0037 0.0097 0.0154
Schistosoma mansoni fkbp-rapamycin associated protein 0.0016 0.0003 0.0005
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Loa Loa (eye worm) hypothetical protein 0.0061 0.0205 0.036
Brugia malayi cytoplasmic intermediate filament protein 0.0071 0.0247 0.0434
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0046 0.0134 0.0424
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0026 0.0048 0.0151
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0026 0.0048 0.0077
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0063 0.0212 0.091
Schistosoma mansoni hypothetical protein 0.0276 0.1174 0.187
Trypanosoma cruzi cysteine peptidase, putative 0.0046 0.0134 0.0424
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0104 0.0399 0.0635
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0114 0.0442 0.1397
Loa Loa (eye worm) animal heme peroxidase 0.059 0.2588 0.455
Schistosoma mansoni hypothetical protein 0.0261 0.1104 0.1758
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0449 0.1581
Echinococcus granulosus hexokinase 0.0718 0.3163 0.5037
Echinococcus multilocularis tubulin alpha 3 chain 0.0281 0.1195 0.1195
Trichomonas vaginalis tubulin epsilon chain, putative 0.0281 0.1195 0.4213
Giardia lamblia Gamma tubulin 0.0206 0.0859 0.3277
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0079 0.0287 0.0287
Echinococcus granulosus single minded 2 0.0102 0.0388 0.0619
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0018 0.0063
Echinococcus granulosus tubulin alpha 3 chain 0.0281 0.1195 0.1904
Loa Loa (eye worm) hypothetical protein 0.0353 0.1519 0.267
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0058 0.0192 0.0606
Echinococcus multilocularis neural cadherin 0.0076 0.0273 0.0273
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.006 0.0211
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Onchocerca volvulus 0.0104 0.0399 0.1261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.032 0.1125
Brugia malayi follicle stimulating hormone receptor 0.0269 0.114 0.2004
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0082 0.0258
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0104 0.0399 0.0701
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0104 0.0399 0.0635
Brugia malayi Cell death protein 3 precursor 0.0021 0.0024 0.0043
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0034 0.0082 0.1165
Schistosoma mansoni pyruvate dehydrogenase 0.0034 0.0082 0.0131
Trypanosoma brucei cytochrome P450, putative 0.009 0.0334 0.1056
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0651 0.2862 0.9048
Plasmodium falciparum tubulin beta chain 0.0343 0.1474 0.4662
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0016 0.0025
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0114 0.0442 0.1397
Schistosoma mansoni heat shock protein 0.0034 0.0082 0.0131
Mycobacterium ulcerans glutaminase 0.0195 0.0809 0.4084
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0037 0.0097 0.0154
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0132 0.0523 0.0919
Brugia malayi EGF-like domain containing protein 0.0076 0.0273 0.048
Trypanosoma cruzi MFS transporter, putative 0.0022 0.0029 0.0092
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0059 0.0197 0.0621
Echinococcus granulosus dna polymerase kappa 0.0037 0.0097 0.0154
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.014 0.0491
Toxoplasma gondii aldehyde dehydrogenase 0.0069 0.0239 0.0754
Onchocerca volvulus DNA topoisomerase 2 homolog 0.046 0.2001 0.6326
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0087 0.032 0.1009
Echinococcus multilocularis lamin dm0 0.0132 0.0523 0.0523
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0063 0.0212 0.0212
Schistosoma mansoni hypothetical protein 0.0056 0.0182 0.0289
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0056 0.018 0.0316
Trypanosoma brucei beta tubulin 0.0343 0.1474 0.4661
Brugia malayi ecdysone receptor 0.0046 0.0138 0.0242
Brugia malayi EGF-like domain containing protein 0.0076 0.0273 0.048
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0038 0.0099 0.0433
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0064 0.0216 0.0343
Loa Loa (eye worm) hypothetical protein 0.0335 0.1436 0.2524
Echinococcus granulosus Smad4 0.0034 0.0083 0.0132
Echinococcus granulosus smad 0.0034 0.0083 0.0132
Schistosoma mansoni nuclear receptor 0.0046 0.0138 0.022
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0036 0.0091 0.0288
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0081 0.0296 0.0296
Schistosoma mansoni z-protein (S1r protein) 0.0016 0.0002 0.0003
Leishmania major DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0003 0.0005
Echinococcus multilocularis hexokinase 0.0718 0.3163 0.3163
Echinococcus multilocularis microtubule associated protein 2 0.141 0.628 0.628
Brugia malayi GRF zinc finger family protein 0.0063 0.0212 0.0373
Schistosoma mansoni hypothetical protein 0.0092 0.0344 0.0549
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0039
Trypanosoma cruzi major cysteine proteinase, putative 0.0036 0.0091 0.0285
Onchocerca volvulus Dual oxidase homolog 0.059 0.2588 0.8184
Echinococcus granulosus delta-like protein 1 0.0076 0.0273 0.0435
Plasmodium vivax SET domain protein, putative 0.0081 0.0296 0.0935
Brugia malayi cytochrome P450 0.0038 0.0099 0.0173
Trichomonas vaginalis tubulin beta chain, putative 0.0281 0.1195 0.4213
Echinococcus granulosus sterol regulatory element binding protein 0.0096 0.036 0.0573
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.0097 0.017
Chlamydia trachomatis pyruvate kinase 0.0027 0.0049 0.006
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0449 0.1418
Brugia malayi hypothetical protein 0.0524 0.2291 0.4027
Loa Loa (eye worm) hypothetical protein 0.0056 0.0182 0.0319
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0016 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0283 0.1205 0.2118
Echinococcus multilocularis pyruvate kinase 0.0027 0.0049 0.0049
Leishmania major phosphatidylinositol 3-kinase, putative 0.0029 0.006 0.0189
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Brugia malayi exodeoxyribonuclease III family protein 0.0064 0.0217 0.0381
Loa Loa (eye worm) phosphatidylinositol 3 0.0029 0.006 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.006 0.0211
Trichomonas vaginalis tubulin beta chain, putative 0.0281 0.1195 0.4213
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0104 0.0399 0.0701
Schistosoma mansoni hypothetical protein 0.1256 0.5586 0.8895
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0191 0.0792 0.1391
Echinococcus granulosus Tubulin alpha 1 chain 0.0281 0.1195 0.1904
Schistosoma mansoni endoplasmin 0.0034 0.0082 0.0131
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Onchocerca volvulus Peroxidasin homolog 0.059 0.2588 0.8184
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0034 0.0082 0.0348
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0037 0.0119
Echinococcus multilocularis Niemann Pick C1 protein 0.0223 0.0933 0.0933
Loa Loa (eye worm) tubulin alpha chain 0.0281 0.1195 0.2101
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.0314 0.0552
Schistosoma mansoni heat shock protein 0.0034 0.0082 0.0131
Echinococcus granulosus GPCR family 2 0.0056 0.0182 0.0289
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0058 0.019 0.019
Schistosoma mansoni intermediate filament proteins 0.0132 0.0523 0.0832
Plasmodium vivax tubulin epsilon chain, putative 0.0206 0.0859 0.2717
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0034 0.0082 0.0258
Echinococcus multilocularis expressed conserved protein 0.0209 0.0872 0.0872
Loa Loa (eye worm) animal heme peroxidase 0.059 0.2588 0.455
Echinococcus multilocularis jun protein 0.0095 0.0357 0.0357
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0045 0.0141
Schistosoma mansoni smad 0.0034 0.0083 0.0132
Loa Loa (eye worm) heterochromatin protein 1 0.005 0.0153 0.027
Loa Loa (eye worm) pyruvate kinase 0.0027 0.0049 0.0086
Mycobacterium ulcerans DNA gyrase subunit B 0.0451 0.1959 1
Schistosoma mansoni cell polarity protein 0.0076 0.0273 0.0435
Giardia lamblia Alpha-tubulin 0.0281 0.1195 0.4559
Onchocerca volvulus Neurogenic locus notch homolog 0.0076 0.0273 0.0864
Loa Loa (eye worm) tubulin alpha-3 chain 0.0164 0.0669 0.1176
Echinococcus granulosus heat shock protein 90 0.0034 0.0082 0.0131
Echinococcus multilocularis peroxidasin 0.059 0.2588 0.2588
Loa Loa (eye worm) nuclear factor I 0.0019 0.0014 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0239 0.1154
Brugia malayi hypothetical protein 0.1279 0.5689 1
Mycobacterium ulcerans epimerase 0.0039 0.0104 0.0463
Loa Loa (eye worm) hypothetical protein 0.0061 0.0205 0.036
Schistosoma mansoni tubulin subunit beta 0.0343 0.1474 0.2348
Onchocerca volvulus 0.0022 0.0029 0.0093
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0316
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0056 0.0182 0.0182
Echinococcus multilocularis caspase 2 0.0021 0.0024 0.0024
Echinococcus multilocularis heat shock protein 90 0.0034 0.0082 0.0082
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0063 0.0212 0.0747
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0046 0.0134 0.0424
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0038 0.0099 0.0433
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0021 0.0024 0.0076
Schistosoma mansoni RAR-like nuclear receptor 0.0104 0.0399 0.0635
Brugia malayi nuclear hormone receptor family member odr-7 0.0046 0.0138 0.0242
Echinococcus multilocularis survival motor neuron protein 1 0.1279 0.5689 0.5689
Loa Loa (eye worm) hypothetical protein 0.0228 0.0957 0.1683
Brugia malayi hypothetical protein 0.0046 0.0138 0.0242
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0049 0.0149 0.0238
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0038 0.0099 0.0311
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0078 0.0282 0.0449
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0026 0.0048 0.0085
Brugia malayi MH1 domain containing protein 0.0034 0.0083 0.0146
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0037 0.0119
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0239 0.1154
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0034 0.0082 0.0082
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0038 0.0099 0.0433
Schistosoma mansoni slit 0.0076 0.0273 0.0435
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0076 0.0273 0.0863
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0114 0.0442 0.1397
Echinococcus granulosus aryl hydrocarbon receptor 0.0114 0.0444 0.0708
Echinococcus multilocularis serine protein kinase ATM 0.0016 0.0003 0.0003
Loa Loa (eye worm) tubulin alpha chain 0.0281 0.1195 0.2101
Plasmodium falciparum metacaspase-like protein 0.0021 0.0024 0.0077
Loa Loa (eye worm) hypoxia-induced factor 1 0.041 0.1778 0.3124
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0333 0.1173
Loa Loa (eye worm) hypothetical protein 0.0096 0.036 0.0633
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0226 0.0948 0.151
Loa Loa (eye worm) hypothetical protein 0.0046 0.0138 0.0242
Toxoplasma gondii alpha-tubulin I, putative 0.0281 0.1195 0.3779
Loa Loa (eye worm) hexokinase 0.0718 0.3163 0.5559
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0046 0.0134 0.0424
Giardia lamblia DNA topoisomerase II 0.0598 0.2621 1
Trichomonas vaginalis tubulin beta chain, putative 0.0281 0.1195 0.4213
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0046 0.0138 0.0138
Onchocerca volvulus Protein ultraspiracle homolog 0.0104 0.0399 0.1261
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Echinococcus multilocularis tubulin alpha chain 0.0281 0.1195 0.1195
Leishmania major DNA topoisomerase 1A 0.0063 0.0212 0.067
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0046 0.0138 0.0436
Brugia malayi CHE-14 protein 0.0096 0.036 0.0633
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Leishmania major developmentally regulated phosphoprotein-like protein 0.0034 0.0082 0.0258
Echinococcus granulosus segment polarity protein dishevelled 0.0016 0.0002 0.0003
Schistosoma mansoni pyruvate kinase 0.0027 0.0049 0.0078
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Brugia malayi bHLH-PAS transcription factor 0.0098 0.0371 0.0652
Echinococcus granulosus carbonic anhydrase 0.0395 0.1707 0.2719
Onchocerca volvulus 0.0022 0.0029 0.0093
Loa Loa (eye worm) heat shock protein 90 0.0034 0.0082 0.0144
Schistosoma mansoni septate junction protein 0.0076 0.0273 0.0435
Onchocerca volvulus Putative cubilin 0.0076 0.0273 0.0863
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0055 0.0179 0.0285
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0056 0.0182 0.0182
Brugia malayi heat shock protein 90 0.0034 0.0082 0.0144
Brugia malayi Steroid receptor seven-up type 2 0.0104 0.0399 0.0701
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0206 0.0859 0.2716
Loa Loa (eye worm) runx1 0.0044 0.0129 0.0226
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0316
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0034 0.0082 0.0288
Schistosoma mansoni tubulin subunit beta 0.0343 0.1474 0.2348
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0082 0.0258
Echinococcus granulosus caspase 8 0.0021 0.0024 0.0039
Echinococcus multilocularis tubulin alpha 3 chain 0.0281 0.1195 0.1195
Trypanosoma brucei DNA topoisomerase ii 0.0651 0.2862 0.9048
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0048 0.0169
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0064 0.0217 0.1041
Trichomonas vaginalis tubulin alpha chain, putative 0.0206 0.0859 0.3028
Echinococcus granulosus slit 2 protein 0.0076 0.0273 0.0435
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0046 0.0138 0.022
Toxoplasma gondii beta-1 tubulin, putative 0.0343 0.1474 0.4661
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0026 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Schistosoma mansoni hypothetical protein 0.0076 0.0273 0.0435
Trypanosoma brucei alpha tubulin 0.0281 0.1195 0.3779
Giardia lamblia DNA topoisomerase III 0.0063 0.0212 0.0809
Schistosoma mansoni tubulin subunit beta 0.009 0.0333 0.053
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Echinococcus multilocularis protein jagged 1 0.0076 0.0273 0.0273
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0095 0.0357 0.0357
Schistosoma mansoni nuclear receptor nhr-48 0.0046 0.0138 0.022
Plasmodium vivax DNA topoisomerase 3, putative 0.0063 0.0212 0.0671
Schistosoma mansoni hypothetical protein 0.0121 0.0475 0.0756
Loa Loa (eye worm) hypothetical protein 0.0085 0.0314 0.0552
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0028 0.0055 0.0173
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0449 0.1418
Trypanosoma brucei zeta tubulin 0.009 0.0333 0.1052
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0138 0.022
Onchocerca volvulus Heterochromatin protein 1 homolog 0.003 0.0064 0.0204
Trichomonas vaginalis guanylate cyclase, putative 0.0058 0.0192 0.0676
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0038 0.0099 0.0433
Trichomonas vaginalis tubulin alpha chain, putative 0.0117 0.0456 0.1604
Trichomonas vaginalis chromobox protein, putative 0.005 0.0153 0.0539
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0046 0.0135 0.0215
Loa Loa (eye worm) hypothetical protein 0.0064 0.0216 0.0379
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0038 0.0099 0.0433
Brugia malayi nuclear hormone receptor 0.0046 0.0138 0.0242
Schistosoma mansoni hypothetical protein 0.0076 0.0273 0.0435
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0016 0.0003 0.0009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0104 0.0399 0.0701
Schistosoma mansoni hypothetical protein 0.0076 0.0273 0.0435
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0029 0.006 0.0096
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0064 0.0217 0.1041
Brugia malayi Cytochrome P450 family protein 0.0111 0.043 0.0756
Onchocerca volvulus Putative organic anion transporter 0.0022 0.0029 0.0093
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0037 0.0118
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0115 0.0449 0.0789
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Brugia malayi Nuclear hormone receptor-like 1 0.0104 0.0399 0.0701
Mycobacterium leprae putative cytochrome p450 0.0038 0.0099 0.1452
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0034 0.0082 0.0348
Entamoeba histolytica pyruvate kinase, putative 0.0019 0.0013 0.0039
Onchocerca volvulus 0.045 0.1958 0.619
Entamoeba histolytica acyl-CoA synthetase, putative 0.0019 0.0014 0.0044
Schistosoma mansoni hypothetical protein 0.0395 0.1707 0.2719
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0148 0.0595 1
Brugia malayi Pyruvate kinase, muscle isozyme 0.0027 0.0049 0.0086
Trichomonas vaginalis tubulin beta-1 chain, putative 0.009 0.0333 0.1173
Trichomonas vaginalis tubulin, putative 0.0117 0.0456 0.1604
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0162 0.0572
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0034 0.0082 0.0232
Chlamydia trachomatis DNA gyrase subunit B 0.0431 0.1871 0.9544
Onchocerca volvulus 0.0046 0.0138 0.0436
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0034 0.0082 0.0258
Toxoplasma gondii heat shock protein 90, putative 0.0034 0.0082 0.0258
Mycobacterium leprae cell division protein FtsZ 0.009 0.0333 0.5489
Schistosoma mansoni aryl hydrocarbon receptor 0.0157 0.0636 0.1012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.002
Schistosoma mansoni Smad4 0.0034 0.0083 0.0132
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0567 0.2484 0.4366
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0037 0.0117
Giardia lamblia Pms1-like protein 0.0034 0.0082 0.0311
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0038 0.0099 0.0433
Loa Loa (eye worm) MH2 domain-containing protein 0.0502 0.2189 0.3848
Loa Loa (eye worm) hexokinase type II 0.0718 0.3163 0.5559
Schistosoma mansoni dishevelled 0.0016 0.0002 0.0003
Leishmania major DNA topoisomerase III, putative 0.0063 0.0212 0.067
Entamoeba histolytica hypothetical protein 0.0024 0.0037 0.0117
Onchocerca volvulus Slit protein homolog 0.0076 0.0273 0.0863
Onchocerca volvulus Chorion peroxidase homolog 0.059 0.2588 0.8184
Trichomonas vaginalis tubulin gamma chain, putative 0.0206 0.0859 0.3028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0003 0.001
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0148 0.0595 0.1881
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0087 0.032 0.1009
Echinococcus granulosus heat shock protein 0.0034 0.0082 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.022 0.0773
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0034 0.0082 0.0348
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0026 0.0048 0.0048
Onchocerca volvulus 0.0076 0.0273 0.0863
Mycobacterium leprae Probable two-component sensor kinase 0.0034 0.0082 0.1165
Brugia malayi Animal haem peroxidase family protein 0.059 0.2588 0.455
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0087 0.032 0.0509
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0029 0.006 0.0189
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0016 0.0025
Brugia malayi hypothetical protein 0.0371 0.1601 0.2814
Plasmodium vivax metacaspase 1, putative 0.0021 0.0024 0.0077
Onchocerca volvulus Pyruvate kinase homolog 0.0027 0.0049 0.0155
Toxoplasma gondii target of rapamycin (TOR), putative 0.0064 0.022 0.0693
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0034 0.0082 0.0288
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0034 0.0082 0.0257
Loa Loa (eye worm) tubulin alpha-2 chain 0.0281 0.1195 0.2101
Trypanosoma brucei Metacaspase-4 0.0021 0.0024 0.0076
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0046 0.0138 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0049 0.0086
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0069 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0283 0.1205 0.2118
Echinococcus multilocularis protein patched 0.0096 0.036 0.036
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0016 0 0.0001
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0064 0.0217 0.0933
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0069 0.024 0.0758
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0018 0.0012 0.0035
Trypanosoma brucei heat shock protein, putative 0.0034 0.0082 0.0258
Mycobacterium ulcerans two component sensor kinase MprB 0.0034 0.0082 0.0348
Giardia lamblia Alpha-tubulin 0.0281 0.1195 0.4559
Chlamydia trachomatis DNA gyrase subunit A 0.0114 0.0442 0.2106
Loa Loa (eye worm) tubulin alpha 2 0.0191 0.0792 0.1391
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0037 0.0117
Schistosoma mansoni pyruvate kinase 0.0027 0.0049 0.0078
Echinococcus multilocularis chromobox protein 1 0.005 0.0153 0.0153
Schistosoma mansoni ap endonuclease 0.0064 0.0217 0.0345
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0087 0.032 0.1009
Plasmodium falciparum DNA gyrase subunit A 0.0114 0.0442 0.1398
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Echinococcus multilocularis Protein lozenge 0.0044 0.0129 0.0129
Echinococcus multilocularis Tubulin alpha 1 chain 0.0281 0.1195 0.1195
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0115 0.0449 0.1418
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0239 0.038
Onchocerca volvulus 0.0718 0.3163 1
Schistosoma mansoni notch 0.0076 0.0273 0.0435
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0046 0.0138 0.0436
Mycobacterium ulcerans DNA topoisomerase I 0.0063 0.0212 0.1018
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0082 0.0258
Echinococcus multilocularis carbonic anhydrase 0.0395 0.1707 0.1707
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.032 0.1125
Schistosoma mansoni thyroid hormone receptor 0.0104 0.0399 0.0635
Loa Loa (eye worm) hypothetical protein 0.0359 0.1546 0.2718
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0055 0.0192
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0167 0.0265
Echinococcus granulosus nuclear factor of activated T cells 5 0.0059 0.0194 0.0308
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0034 0.0082 0.0348
Echinococcus granulosus cytochrome P450 2K1 0.0038 0.0099 0.0157
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0451 0.1959 1
Onchocerca volvulus DNA topoisomerase 2 homolog 0.046 0.2001 0.6326
Echinococcus granulosus thyroid hormone receptor alpha 0.0046 0.0138 0.022
Schistosoma mansoni organic anion transporter 0.0022 0.0029 0.0047
Schistosoma mansoni carbonic anhydrase-related 0.0395 0.1707 0.2719
Trypanosoma brucei unspecified product 0.0037 0.0097 0.0305
Brugia malayi hypothetical protein 0.0058 0.019 0.0334
Schistosoma mansoni smad1 5 8 and 0.0034 0.0083 0.0132
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0038 0.0099 0.0433
Schistosoma mansoni carbonic anhydrase 0.0395 0.1707 0.2719
Trichomonas vaginalis DNA topoisomerase II, putative 0.0632 0.2774 0.9778
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Toxoplasma gondii LsmAD domain-containing protein 0.0124 0.0486 0.1536
Giardia lamblia DNA topoisomerase III 0.0063 0.0212 0.0809
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0024 0.0085
Brugia malayi notch-like transmembrane receptor 0.0076 0.0273 0.048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0183 0.0643
Echinococcus multilocularis mitogen activated protein kinase 3 0.0115 0.0449 0.0449
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0104 0.0399 0.0635
Mycobacterium ulcerans putative regulatory protein 0.0098 0.0371 0.1835
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0029 0.006 0.0189
Schistosoma mansoni lipoxygenase 0.0044 0.0127 0.0203
Echinococcus multilocularis hypothetical protein 0.0281 0.1195 0.1195
Schistosoma mansoni DNA helicase recq5 0.0016 0 0.0001
Treponema pallidum DNA topoisomerase I (topA) 0.0063 0.0212 0.056
Trichomonas vaginalis tubulin gamma chain, putative 0.0343 0.1474 0.5196
Giardia lamblia DINP protein human, muc B family 0.0037 0.0097 0.0368
Echinococcus multilocularis notch 0.0076 0.0273 0.0273
Trichomonas vaginalis glutaminase, putative 0.0195 0.0809 0.2849
Giardia lamblia Beta tubulin 0.0343 0.1474 0.5624
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0104 0.0399 0.0635
Trichomonas vaginalis receptor histidine kinase, putative 0.0034 0.0082 0.0288
Trypanosoma cruzi Heat shock protein 83, putative 0.0034 0.0082 0.0258
Trypanosoma brucei heat shock protein, putative 0.0034 0.0082 0.0258
Echinococcus granulosus caspase 0.0079 0.0286 0.0455
Echinococcus granulosus chromobox protein 1 0.005 0.0153 0.0244
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0034 0.0082 0.0348
Echinococcus granulosus regulator of G protein signaling 7 0.0016 0.0002 0.0003
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Loa Loa (eye worm) hypothetical protein 0.0046 0.0138 0.0242
Brugia malayi hexokinase 0.0718 0.3163 0.5559
Echinococcus granulosus peroxisome assembly protein 26 0.0281 0.1195 0.1904
Brugia malayi EGF-like domain containing protein 0.0076 0.0273 0.048
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0115 0.0449 0.1418
Loa Loa (eye worm) cytochrome P450 family protein 0.0111 0.043 0.0756
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0135 0.0621
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.0314 0.05
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0241 0.1013 0.3203
Brugia malayi Muscle positioning protein 4 0.0076 0.0273 0.048
Trypanosoma cruzi zeta tubulin, putative 0.009 0.0333 0.1052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0046 0.0134 0.0424
Brugia malayi GCC2 and GCC3 family protein 0.0076 0.0273 0.048
Brugia malayi DNA topoisomerase III 0.0063 0.0212 0.0373
Trypanosoma brucei beta tubulin 0.0343 0.1474 0.4661
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0148 0.0595 0.2986
Echinococcus multilocularis carbonic anhydrase 0.0395 0.1707 0.1707
Leishmania major cathepsin L-like protease 0.0046 0.0134 0.0424
Echinococcus granulosus pyruvate kinase 0.0027 0.0049 0.0078
Onchocerca volvulus 0.0272 0.1156 0.3655
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.016 0.0563
Leishmania major cathepsin L-like protease 0.0046 0.0134 0.0424
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0005
Mycobacterium ulcerans cell division protein FtsZ 0.009 0.0333 0.1639
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0079 0.0287 0.0905
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0016 0.0002 0.0004
Trypanosoma brucei heat shock protein, putative 0.0034 0.0082 0.0258
Trypanosoma brucei DNA topoisomerase III, putative 0.0063 0.0212 0.067
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0046 0.0135 0.0215
Trypanosoma brucei Heat shock protein 83, putative 0.0034 0.0082 0.0258
Schistosoma mansoni caspase-7 (C14 family) 0.0021 0.0024 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.014 0.0492
Loa Loa (eye worm) hypothetical protein 0.0028 0.0055 0.0096
Trypanosoma brucei developmentally regulated phosphoprotein 0.0034 0.0082 0.0258
Trypanosoma cruzi metacaspase, putative 0.0021 0.0024 0.0076
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0016 0.0002 0.0002
Chlamydia trachomatis DNA gyrase subunit B 0.0451 0.1959 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0079 0.0287 0.0287
Echinococcus granulosus dna polymerase eta 0.0037 0.0097 0.0154
Trypanosoma cruzi epsilon tubulin, putative 0.0206 0.0859 0.2716
Schistosoma mansoni DNA topoisomerase II 0.0632 0.2774 0.4418
Toxoplasma gondii transporter, major facilitator family protein 0.0022 0.0029 0.0092
Mycobacterium tuberculosis Cell division protein FtsZ 0.009 0.0333 0.1639
Echinococcus granulosus Tubulin beta 2C chain 0.0343 0.1474 0.2348
Echinococcus multilocularis transfer RNA-Lys 0.0098 0.0371 0.0371
Leishmania major DNA polymerase eta, putative 0.0037 0.0097 0.0305
Echinococcus multilocularis rho GTPase activating protein 20 0.0063 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0056 0.0181 0.0319
Brugia malayi DNA topoisomerase III beta-1 0.0063 0.0212 0.0373
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0059 0.0197 0.0621
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0097 0.0305
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0261 0.1104 0.1941
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0034 0.0082 0.0348
Echinococcus granulosus tubulin alpha 3 chain 0.0281 0.1195 0.1904
Echinococcus granulosus serine protein kinase ATM 0.0016 0.0003 0.0005
Trichomonas vaginalis tubulin, putative 0.0117 0.0456 0.1604
Loa Loa (eye worm) hypothetical protein 0.0108 0.0415 0.073
Entamoeba histolytica hypothetical protein 0.0276 0.1174 0.3711
Loa Loa (eye worm) hypothetical protein 0.0223 0.0933 0.164
Echinococcus multilocularis Tubulin beta 2C chain 0.0343 0.1474 0.1474
Treponema pallidum exodeoxyribonuclease (exoA) 0.0064 0.0217 0.0574
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0104 0.0399 0.0635
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.014 0.0491
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0 0.00000000010244
Echinococcus granulosus neuropeptide receptor A26 0.0948 0.4201 0.669
Onchocerca volvulus Putative organic anion transporter 0.0022 0.0029 0.0093
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0588 0.2578 0.4532
Plasmodium falciparum DNA gyrase subunit B 0.0451 0.1959 0.6194
Brugia malayi Hexokinase family protein 0.0718 0.3163 0.5559
Brugia malayi Animal haem peroxidase family protein 0.059 0.2588 0.455
Echinococcus multilocularis tubulin epsilon chain 0.0206 0.0859 0.0859
Echinococcus granulosus hexokinase 0.0718 0.3163 0.5037
Schistosoma mansoni notch 0.0076 0.0273 0.0435
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0052
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0097 0.0305
Trypanosoma brucei unspecified product 0.0026 0.0045 0.0141
Trypanosoma cruzi tubulin delta chain 0.009 0.0333 0.1052
Toxoplasma gondii beta-tubulin, putative 0.0343 0.1474 0.4661
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0038 0.0099 0.0433
Trypanosoma cruzi metacaspase, putative 0.0021 0.0024 0.0076
Leishmania major hexokinase, putative 0.0718 0.3163 1
Loa Loa (eye worm) hypothetical protein 0.0139 0.0554 0.0973
Trypanosoma cruzi cruzipain precursor, putative 0.0046 0.0134 0.0424
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Onchocerca volvulus Peroxidase homolog 0.059 0.2588 0.8184
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0058 0.019 0.0334
Trypanosoma brucei pyruvate kinase 1, putative 0.0027 0.0049 0.0154
Brugia malayi sodium-independent organic anion transporter family protein 0.0022 0.0029 0.0052
Schistosoma mansoni carbonic anhydrase-related 0.0395 0.1707 0.2719
Echinococcus granulosus Niemann Pick C1 protein 0.0318 0.1364 0.2172
Loa Loa (eye worm) hypothetical protein 0.0228 0.0957 0.1683
Schistosoma mansoni steroid hormone receptor ad4bp 0.0104 0.0399 0.0635
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0115 0.0449 0.1418
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0038 0.0099 0.0433
Echinococcus granulosus carbonic anhydrase II 0.0588 0.2578 0.4106
Mycobacterium leprae Probable pyruvate kinase PykA 0.0027 0.0049 0.0596
Trichomonas vaginalis tubulin beta chain, putative 0.0281 0.1195 0.4213
Brugia malayi bZIP transcription factor family protein 0.0095 0.0357 0.0628
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0038 0.0099 0.0433
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0083 0.0132
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0138 0.0138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.024 0.0844
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0063 0.0212 0.067
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0003 0.001
Echinococcus multilocularis tubulin alpha 1C chain 0.0281 0.1195 0.1195
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0114 0.0442 0.2106
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0081 0.0296 0.0934
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0177 0.0727 0.1278
Trypanosoma brucei hexokinase, putative 0.0718 0.3163 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0395 0.1707 0.3001
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0034 0.0082 0.0348
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0038 0.0099 0.0433
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0104 0.0399 0.0399
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.022 0.0773
Echinococcus granulosus notch 0.0076 0.0273 0.0435
Schistosoma mansoni notch 0.0076 0.0273 0.0435
Brugia malayi hypothetical protein 0.0022 0.0029 0.0052
Loa Loa (eye worm) tubulin gamma chain 0.0206 0.0859 0.151
Echinococcus granulosus tubulin beta 1 chain 0.0343 0.1474 0.2348
Echinococcus multilocularis dna polymerase kappa 0.0037 0.0097 0.0097
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0027 0.0049 0.0178
Onchocerca volvulus Peroxidase homolog 0.059 0.2588 0.8184
Schistosoma mansoni hypothetical protein 0.0056 0.0182 0.0289
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0034 0.0082 0.1165
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0037 0.0097 0.017
Schistosoma mansoni smad1 5 8 and 0.0034 0.0083 0.0132
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0087 0.032 0.0509
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0037 0.0097 0.034
Schistosoma mansoni organic anion transporter 0.0022 0.0029 0.0047
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0029 0.006 0.006
Trypanosoma brucei DNA topoisomerase IA, putative 0.0063 0.0212 0.067
Brugia malayi PAS domain containing protein 0.0156 0.0634 0.1114
Echinococcus granulosus tubulin alpha chain 0.0281 0.1195 0.1904
Toxoplasma gondii DNA topoisomerase 2, putative 0.0632 0.2774 0.8771
Loa Loa (eye worm) hypothetical protein 0.0022 0.0028 0.0049
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0588 0.2578 0.4106
Brugia malayi kinase, mitochondrial precursor 0.0034 0.0082 0.0144
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0052
Trypanosoma cruzi heat shock protein 90, putative 0.0034 0.0082 0.0258
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0104 0.0399 0.0399
Trichomonas vaginalis tubulin epsilon chain, putative 0.0343 0.1474 0.5196
Brugia malayi hypothetical protein 0.0075 0.0265 0.0466
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0127 0.0503 0.8412
Echinococcus granulosus tubulin alpha 0.0206 0.0859 0.1368
Loa Loa (eye worm) hypothetical protein 0.0046 0.0138 0.0242
Brugia malayi Cell division protein ftsZ 0.009 0.0333 0.0585
Echinococcus granulosus Tubulin alpha 1 chain 0.0281 0.1195 0.1904
Brugia malayi MH2 domain containing protein 0.0034 0.0083 0.0146
Brugia malayi EGF-like domain containing protein 0.0076 0.0273 0.048
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0024 0.0085
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0117 0.0456 0.1604
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0038 0.0099 0.0433
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0449 0.0715
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0034 0.0082 0.0258
Trypanosoma brucei epsilon tubulin 0.0206 0.0859 0.2716
Schistosoma mansoni peroxidasin 0.059 0.2588 0.4122
Trichomonas vaginalis tubulin beta chain, putative 0.0281 0.1195 0.4213
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0014 0.0025
Schistosoma mansoni retinoic acid receptor RXR 0.0104 0.0399 0.0635
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0016 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0046 0.0138 0.0242
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0056 0.0182 0.0289
Leishmania major alpha tubulin 0.0281 0.1195 0.3779
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0018 0.0063
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0038 0.0099 0.0433
Trichomonas vaginalis heat shock protein, putative 0.0034 0.0082 0.0288
Schistosoma mansoni tubulin subunit beta 0.0343 0.1474 0.2348
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Brugia malayi Tubulin alpha chain 0.0281 0.1195 0.2101
Plasmodium falciparum DNA topoisomerase 2 0.0632 0.2774 0.8771
Mycobacterium ulcerans two component regulator - sensor kinase 0.0034 0.0082 0.0348
Onchocerca volvulus 0.059 0.2588 0.8184
Echinococcus multilocularis fibropellin Ia 0.0076 0.0273 0.0273
Schistosoma mansoni carbonic anhydrase-related 0.0395 0.1707 0.2719
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0016 0 0.0001
Echinococcus multilocularis peroxisome assembly protein 26 0.0281 0.1195 0.1195
Loa Loa (eye worm) cytochrome P450 0.0038 0.0099 0.0173
Onchocerca volvulus 0.0261 0.1104 0.3491
Echinococcus multilocularis beta tubulin 0.0343 0.1474 0.1474
Leishmania major alpha tubulin 0.0281 0.1195 0.3779
Echinococcus multilocularis fat cadherin tumor suppressor 0.0076 0.0273 0.0273
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0038 0.0099 0.0433
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0038 0.0099 0.0433
Echinococcus granulosus bloom syndrome protein 0.0016 0 0.0001
Schistosoma mansoni hexokinase 0.0718 0.3163 0.5037
Onchocerca volvulus 0.009 0.0332 0.1051
Echinococcus multilocularis thyroid hormone receptor alpha 0.0104 0.0399 0.0399
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Entamoeba histolytica tubulin gamma chain 0.0206 0.0859 0.2716
Brugia malayi Peroxidasin 0.059 0.2588 0.455
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.032 0.1125
Loa Loa (eye worm) hypothetical protein 0.0058 0.0192 0.0337
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0059 0.0197 0.0621
Onchocerca volvulus 0.0371 0.1601 0.5061
Schistosoma mansoni hypothetical protein 0.0056 0.0182 0.0289
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0034 0.0082 0.0142
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0034 0.0082 0.0082
Trypanosoma brucei heat shock protein, putative 0.0034 0.0082 0.0258
Echinococcus multilocularis mitogen activated protein kinase 0.0115 0.0449 0.0449
Onchocerca volvulus 0.0022 0.0028 0.0088
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0022
Trichomonas vaginalis tubulin gamma chain, putative 0.0206 0.0859 0.3028
Schistosoma mansoni ap endonuclease 0.0064 0.0217 0.0345
Echinococcus multilocularis segment polarity protein dishevelled 0.0016 0.0002 0.0002
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0046 0.0137 0.0481
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0029 0.006 0.0189
Giardia lamblia GTOR 0.0087 0.032 0.1218
Schistosoma mansoni tubulin subunit gamma 0.0206 0.0859 0.1368
Trypanosoma brucei DNA polymerase eta, putative 0.0037 0.0097 0.0305
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0104 0.0399 0.0701
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.0314 0.05
Trypanosoma cruzi metacaspase 5, putative 0.0021 0.0024 0.0076
Brugia malayi nuclear receptor RXR 0.0058 0.019 0.0334
Leishmania major alpha tubulin 0.0281 0.1195 0.3779
Trypanosoma brucei PAB1-binding protein , putative 0.0124 0.0486 0.1536
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Schistosoma mansoni transcription factor LCR-F1 0.0276 0.1174 0.187
Brugia malayi Endoplasmin precursor 0.0034 0.0082 0.0144
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0059 0.0194 0.0194
Toxoplasma gondii endonuclease IV APN 0.0148 0.0595 0.188
Echinococcus granulosus ubiquitin specific protease 41 0.0026 0.0048 0.0077
Trypanosoma brucei metacaspase 5, putative 0.0021 0.0024 0.0076
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0079 0.0287 0.0905
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0043
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0034 0.0082 0.0131
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0096 0.036 0.0633
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0029 0.006 0.0106
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0104 0.0399 0.0701
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0063 0.0212 0.0373
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0037 0.0117
Trypanosoma cruzi pyruvate kinase 2, putative 0.0027 0.0049 0.0154
Leishmania major hexokinase, putative 0.0718 0.3163 1
Trichomonas vaginalis guanylate cyclase, putative 0.0058 0.0192 0.0676
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0162 0.0572
Loa Loa (eye worm) hypothetical protein 0.0046 0.0138 0.0242
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Echinococcus granulosus tumor protein p63 0.0382 0.1652 0.263
Echinococcus granulosus lamin dm0 0.0132 0.0523 0.0832
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0064 0.0217 0.0685
Treponema pallidum hexokinase (hxk) 0.0718 0.3163 1
Schistosoma mansoni hypothetical protein 0.0092 0.0344 0.0549
Trypanosoma cruzi alpha tubulin, putative 0.0281 0.1195 0.3779
Schistosoma mansoni patched 1 0.0096 0.036 0.0573
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.022 0.0773
Onchocerca volvulus 0.0076 0.0273 0.0863
Brugia malayi Animal haem peroxidase family protein 0.059 0.2588 0.455
Echinococcus granulosus peroxidasin 0.059 0.2588 0.4122
Loa Loa (eye worm) carbonic anhydrase 3 0.0588 0.2578 0.4532
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0034 0.0082 0.0257
Brugia malayi hypothetical protein 0.0139 0.0554 0.0973
Echinococcus granulosus caspase 3 0.0058 0.019 0.0303
Leishmania major metacaspase, putative 0.0021 0.0024 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0085
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0079 0.0286 0.0286
Brugia malayi hypothetical protein 0.0138 0.055 0.0966
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0022 0.0029 0.0029
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0046 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0104 0.0399 0.0701
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0024 0.0085
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0034 0.0082 0.0348
Loa Loa (eye worm) glutaminase 2 0.0195 0.0809 0.1421
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0038 0.0099 0.0433
Onchocerca volvulus 0.0076 0.0273 0.0863
Brugia malayi MH1 domain containing protein 0.0034 0.0083 0.0146
Loa Loa (eye worm) DIX domain-containing protein 0.0016 0.0002 0.0004
Treponema pallidum cell division protein FtsZ 0.009 0.0333 0.0946
Giardia lamblia Pyruvate kinase 0.0027 0.0049 0.0185
Leishmania major DNA topoisomerase III, putative 0.0063 0.0212 0.067
Loa Loa (eye worm) DNA topoisomerase III 0.0063 0.0212 0.0373
Loa Loa (eye worm) steroid hormone receptor 0.0104 0.0399 0.0701
Plasmodium falciparum tubulin gamma chain 0.0206 0.0859 0.2717
Trypanosoma cruzi metacaspase 5, putative 0.0021 0.0024 0.0076
Trichomonas vaginalis set domain proteins, putative 0.0646 0.2837 1
Leishmania major epsilon tubulin, putative 0.0206 0.0859 0.2716
Schistosoma mansoni tubulin subunit alpha 0.0281 0.1195 0.1904
Brugia malayi N-terminal motif family protein 0.0335 0.1436 0.2524
Plasmodium vivax hexokinase, putative 0.0718 0.3163 1
Onchocerca volvulus 0.0056 0.0181 0.0573
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0022 0.0029 0.0047
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0087 0.032 0.1009
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0004
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0016 0.0003 0.0005
Brugia malayi photoreceptor-specific nuclear receptor 0.0104 0.0399 0.0701
Giardia lamblia Heat shock protein HSP 90-alpha 0.0034 0.0082 0.0311
Echinococcus granulosus carbonic anhydrase 0.0395 0.1707 0.2719
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0046 0.0138 0.0138
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0104 0.0399 0.0701
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0046 0.0134 0.0424
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Loa Loa (eye worm) hypothetical protein 0.0395 0.1707 0.3001
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0114 0.0442 0.1397
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0343 0.1474 0.1474
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0056 0.0182 0.0289
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0632 0.2774 0.4876
Brugia malayi Pyruvate kinase, M2 isozyme 0.0027 0.0049 0.0086
Echinococcus granulosus Tubulin beta 2C chain 0.0343 0.1474 0.2348
Brugia malayi Cytochrome P450 family protein 0.0038 0.0099 0.0173
Brugia malayi hypothetical protein 0.0016 0.0002 0.0004
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0104 0.0399 0.0701
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0058 0.0192 0.0676
Loa Loa (eye worm) hypothetical protein 0.0148 0.0595 0.1046
Echinococcus granulosus Tubulin beta 2C chain 0.0343 0.1474 0.2348
Mycobacterium ulcerans endonuclease IV 0.0148 0.0595 0.2986
Trypanosoma cruzi DNA topoisomerase III, putative 0.0063 0.0212 0.067
Echinococcus granulosus hexokinase 0.0718 0.3163 0.5037
Entamoeba histolytica hexokinase 1 0.0718 0.3163 1
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0451 0.1959 1
Echinococcus multilocularis dna polymerase eta 0.0037 0.0097 0.0097
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0058 0.0192 0.0676
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.024 0.0844
Loa Loa (eye worm) hypothetical protein 0.0081 0.0296 0.052
Loa Loa (eye worm) hypothetical protein 0.0139 0.0554 0.0973
Echinococcus multilocularis protein jagged 2 0.0076 0.0273 0.0273
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0104 0.0399 0.0701
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0026 0.0048 0.0169
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0632 0.2774 0.2774
Schistosoma mansoni notch 0.0076 0.0273 0.0435
Brugia malayi Cytochrome P450 family protein 0.009 0.0334 0.0588
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0104 0.0399 0.0701
Trichomonas vaginalis tubulin, putative 0.0343 0.1474 0.5196
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0114 0.0442 0.22
Loa Loa (eye worm) pax transcription factor protein 2 0.0272 0.1156 0.2032
Loa Loa (eye worm) hexokinase 0.045 0.1958 0.3441
Echinococcus granulosus carbonic anhydrase 0.0395 0.1707 0.2719
Echinococcus multilocularis carbonic anhydrase 0.0395 0.1707 0.1707
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0052
Brugia malayi hypothetical protein 0.0056 0.018 0.0316
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0064 0.0217 0.0826
Brugia malayi Probable DNA topoisomerase II 0.0632 0.2774 0.4876
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0449 0.1581
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.024 0.0844
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0104 0.0399 0.0701
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0449 0.1581
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0104 0.0399 0.0399
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0083 0.0146
Trypanosoma brucei beta tubulin 0.0206 0.0859 0.2716
Mycobacterium tuberculosis Conserved hypothetical protein 0.0127 0.05 0.2498
Toxoplasma gondii pyruvate kinase PyK1 0.0027 0.0049 0.0154
Echinococcus granulosus regulator of G protein signaling 7 0.0016 0.0002 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.006 0.0211
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0046 0.0134 0.0424
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0395 0.1707 0.3001
Brugia malayi hypothetical protein 0.008 0.0289 0.0508
Echinococcus multilocularis 0.0038 0.0099 0.0099
Toxoplasma gondii FATC domain-containing protein 0.0016 0.0003 0.0009
Echinococcus granulosus protein jagged 2 0.0076 0.0273 0.0435
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0588 0.2578 0.8152
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0058 0.0192 0.0606
Trypanosoma brucei alpha tubulin 0.0281 0.1195 0.3779
Echinococcus granulosus protein jagged 1 0.0076 0.0273 0.0435
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0097 0.0305
Leishmania major alpha tubulin 0.0281 0.1195 0.3779
Loa Loa (eye worm) hypothetical protein 0.0036 0.0092 0.0162
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0296 0.0471
Trypanosoma brucei beta tubulin 0.0343 0.1474 0.4661
Trichomonas vaginalis ap endonuclease, putative 0.0064 0.0217 0.0763
Echinococcus granulosus protein jagged 2 0.0076 0.0273 0.0435
Schistosoma mansoni jun-related protein 0.0077 0.0277 0.0441
Plasmodium vivax DNA gyrase subunit A, putative 0.0114 0.0442 0.1398
Brugia malayi tailless protein 0.0046 0.0138 0.0242
Loa Loa (eye worm) hypothetical protein 0.0046 0.0138 0.0242
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0223 0.0933 0.2949
Chlamydia trachomatis DNA topoisomerase I 0.0063 0.0212 0.091
Onchocerca volvulus Hexokinase homolog 0.045 0.1958 0.619
Giardia lamblia Kinase, CMGC MAPK 0.0115 0.0449 0.1711
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0058 0.019 0.0303
Echinococcus multilocularis FTZ F1 alpha 0.0104 0.0399 0.0399
Schistosoma mansoni tubulin subunit beta 0.0343 0.1474 0.2348
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0063 0.0212 0.0338
Brugia malayi sodium-independent organic anion transporter family protein 0.0022 0.0029 0.0052
Echinococcus multilocularis hexokinase 0.0718 0.3163 0.3163
Trichomonas vaginalis tubulin beta chain, putative 0.0343 0.1474 0.5196
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0038 0.0099 0.0433
Chlamydia trachomatis DNA gyrase subunit A 0.0114 0.0442 0.2106
Echinococcus granulosus tubulin subunit TubB 0.0281 0.1195 0.1904
Trypanosoma brucei tubulin gamma chain 0.0206 0.0859 0.2716
Loa Loa (eye worm) tubulin beta chain 0.0343 0.1474 0.2592
Leishmania major alpha tubulin 0.0281 0.1195 0.3779
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Onchocerca volvulus 0.0046 0.0138 0.0436
Schistosoma mansoni hypothetical protein 0.0076 0.0273 0.0435
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0022 0.0029 0.0052
Brugia malayi nuclear receptor NHR-88 0.0104 0.0399 0.0701
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0241 0.1013 0.3203
Schistosoma mansoni tubulin subunit epsilon 0.0206 0.0859 0.1368
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0059 0.0194 0.0309
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0135 0.0621
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0114 0.0444 0.0781
Leishmania major hypothetical protein, conserved 0.0034 0.0082 0.0258
Trypanosoma cruzi zeta tubulin, putative 0.009 0.0333 0.1052
Onchocerca volvulus Cell death protein 3 homolog 0.0021 0.0024 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0104 0.0399 0.0701
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0024 0.0085
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0097 0.0305
Echinococcus granulosus nuclear receptor nhr 48 0.0046 0.0138 0.022
Schistosoma mansoni hypothetical protein 0.0076 0.0273 0.0435
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0104 0.0399 0.0635
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Brugia malayi nuclear receptor RXR 0.0046 0.0138 0.0242
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0135 0.0621
Echinococcus granulosus chromobox protein 1 0.005 0.0153 0.0244
Trichomonas vaginalis tubulin alpha chain, putative 0.0117 0.0456 0.1604
Trypanosoma cruzi cysteine peptidase, putative 0.0046 0.0134 0.0424
Trichomonas vaginalis heat shock protein, putative 0.0034 0.0082 0.0288
Schistosoma mansoni lamin 0.0132 0.0523 0.0832
Schistosoma mansoni tubulin subunit alpha 0.009 0.0333 0.053
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Toxoplasma gondii cytochrome p450 superfamily protein 0.0038 0.0099 0.0311
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0069 0.024 0.0758
Echinococcus multilocularis caspase 3 0.0058 0.019 0.019
Loa Loa (eye worm) beta-tubulin 0.0343 0.1474 0.2592
Schistosoma mansoni hypothetical protein 0.0077 0.0277 0.0441
Schistosoma mansoni notch 0.0076 0.0273 0.0435
Mycobacterium leprae Conserved hypothetical protein 0.0038 0.0099 0.1452
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0104 0.0399 0.0399
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0079 0.0287 0.0456
Leishmania major 4-coumarate:coa ligase-like protein 0.0019 0.0014 0.0044
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0079 0.0287 0.0906
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0083 0.0132
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0038 0.0099 0.0433
Onchocerca volvulus Bile acid receptor homolog 0.0104 0.0399 0.1261
Plasmodium vivax ataxin-2 like protein, putative 0.0124 0.0486 0.1537
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.024 0.0844
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0024 0.0085
Loa Loa (eye worm) hypothetical protein 0.0353 0.1519 0.267
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0239 0.1154
Leishmania major alpha tubulin 0.0281 0.1195 0.3779
Echinococcus granulosus Niemann Pick C1 protein 0.0223 0.0933 0.1486
Brugia malayi hypoxia-induced factor 1 0.041 0.1778 0.3124
Echinococcus multilocularis slit 2 protein 0.0076 0.0273 0.0273
Echinococcus multilocularis Tubulin alpha 1 chain 0.0281 0.1195 0.1195
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0082 0.0258
Plasmodium falciparum tubulin delta chain, putative 0.009 0.0333 0.1053
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Echinococcus multilocularis neuropeptide s receptor 0.0948 0.4201 0.4201
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0063 0.0212 0.341
Loa Loa (eye worm) hypothetical protein 0.0058 0.019 0.0334
Schistosoma mansoni notch 0.0076 0.0273 0.0435
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0064 0.0217 0.0685
Loa Loa (eye worm) nuclear hormone receptor 0.0046 0.0138 0.0242
Brugia malayi nuclear hormone receptor 0.0104 0.0399 0.0701
Trypanosoma cruzi tubulin delta chain 0.009 0.0333 0.1052
Leishmania major cytochrome p450-like protein 0.009 0.0334 0.1056
Trypanosoma brucei pyruvate kinase 1 0.0027 0.0049 0.0154
Toxoplasma gondii hexokinase 0.0718 0.3163 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0016 0 0.0001
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0395 0.1707 0.3001
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0034 0.0082 0.0257
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Loa Loa (eye worm) hypothetical protein 0.0016 0 0.0001
Loa Loa (eye worm) endoplasmin 0.0034 0.0082 0.0144
Loa Loa (eye worm) hypothetical protein 0.0129 0.0512 0.0899
Brugia malayi hypothetical protein 0.0276 0.1174 0.2064
Giardia lamblia Delta tubulin 0.009 0.0333 0.1269
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0038 0.0099 0.0433
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0115 0.0449 0.1418
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0296 0.0471
Onchocerca volvulus 0.0019 0.0014 0.0045
Brugia malayi Tubulin alpha chain 0.009 0.0333 0.0585
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0022 0.0029 0.0029
Leishmania major pyruvate kinase 0.0027 0.0049 0.0154
Echinococcus multilocularis neurogenic locus protein delta 0.0076 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0025
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0016 0.0003 0.0005
Echinococcus multilocularis neurogenic locus notch protein 0.0076 0.0273 0.0273
Schistosoma mansoni coup transcription factor 0.0104 0.0399 0.0635
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0104 0.0399 0.0635
Entamoeba histolytica hypothetical protein 0.0276 0.1174 0.3711
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.014 0.0492
Trypanosoma brucei heat shock protein, putative 0.0034 0.0082 0.0258
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0083 0.0083
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0079 0.0287 0.0905
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0046 0.0134 0.0424
Echinococcus multilocularis hexokinase type 2 0.0718 0.3163 0.3163
Onchocerca volvulus Protein cycle homolog 0.0056 0.0182 0.0574
Trichomonas vaginalis chromobox protein, putative 0.005 0.0153 0.0539
Echinococcus multilocularis tubulin gamma 1 chain 0.0206 0.0859 0.0859
Loa Loa (eye worm) hypothetical protein 0.0395 0.1707 0.3001
Echinococcus multilocularis beta tubulin 0.0343 0.1474 0.1474
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0064 0.0217 0.0381
Loa Loa (eye worm) pyruvate kinase 0.0027 0.0049 0.0086
Entamoeba histolytica tubulin alpha chain, putative 0.0281 0.1195 0.3779
Toxoplasma gondii isocitrate dehydrogenase 0.0079 0.0287 0.0905
Leishmania major protein kinase, putative 0.0059 0.0197 0.0621
Loa Loa (eye worm) hypothetical protein 0.0104 0.0399 0.0701
Echinococcus granulosus Tubulin beta 2C chain 0.0343 0.1474 0.2348
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0079 0.0287 0.14
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.016 0.0563
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0316
Leishmania major alpha tubulin 0.0281 0.1195 0.3779
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0034 0.0082 0.0288
Toxoplasma gondii EGF family domain-containing protein 0.0076 0.0273 0.0862
Brugia malayi hypothetical protein 0.0058 0.019 0.0334
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Loa Loa (eye worm) isocitrate dehydrogenase 0.0079 0.0287 0.0504
Schistosoma mansoni DNA helicase recq1 0.0016 0 0.0001
Echinococcus granulosus Tubulin beta 2C chain 0.0343 0.1474 0.2348
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Trypanosoma brucei protein kinase, putative 0.0115 0.0449 0.1418
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0104 0.0399 0.0399
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.022 0.0773
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0164 0.0669 0.2357
Loa Loa (eye worm) hypothetical protein 0.0092 0.0346 0.0607
Trypanosoma cruzi cytochrome P450, putative 0.009 0.0334 0.1056
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0148 0.0595 0.1046
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Mycobacterium leprae Possible regulatory protein 0.0058 0.0192 0.3059
Brugia malayi Cytochrome P450 family protein 0.009 0.0334 0.0588
Brugia malayi Pre-SET motif family protein 0.0567 0.2484 0.4366
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0071 0.0247 0.0434
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0016 0.0004 0.0006
Trypanosoma brucei zeta tubulin, putative 0.009 0.0333 0.1052
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0034 0.0082 0.0348
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0177 0.0727 0.1278
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0058 0.019 0.0303
Leishmania major alpha tubulin 0.0281 0.1195 0.3779
Mycobacterium tuberculosis Possible two component sensor kinase 0.0034 0.0082 0.0348
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0588 0.2578 0.4532
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0104 0.0399 0.0701
Echinococcus multilocularis caspase 8 0.0021 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0046 0.0138 0.0242
Echinococcus granulosus survival motor neuron protein 1 0.1279 0.5689 0.906
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0082 0.0259
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0034 0.0082 0.0348
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0034 0.0082 0.0348
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0043
Plasmodium falciparum endoplasmin, putative 0.0034 0.0082 0.0259
Trypanosoma cruzi target of rapamycin kinase 3 0.0069 0.024 0.0758
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0038 0.0099 0.0433
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0104 0.0399 0.0701
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0085
Loa Loa (eye worm) hypothetical protein 0.0046 0.0138 0.0242
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Brugia malayi orphan nuclear receptor NR2E1 0.0046 0.0138 0.0242
Brugia malayi hypothetical protein 0.059 0.2588 0.455
Echinococcus multilocularis Tubulin beta 2C chain 0.0343 0.1474 0.1474
Plasmodium falciparum ataxin-2 like protein, putative 0.0124 0.0486 0.1537
Loa Loa (eye worm) DR-78 0.0046 0.0138 0.0242
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0016 0 0.0001
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0046 0.0138 0.0242
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0104 0.0399 0.0701
Mycobacterium tuberculosis Conserved protein 0.0034 0.0082 0.0348
Brugia malayi tubulin alpha chain - mouse 0.0281 0.1195 0.2101
Trypanosoma brucei DNA topoisomerase III, putative 0.0063 0.0212 0.067
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0588 0.2578 0.4106
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0316
Trypanosoma brucei carbonic anhydrase-like protein 0.0588 0.2578 0.8152
Brugia malayi Animal haem peroxidase family protein 0.059 0.2588 0.455
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0087 0.032 0.1009
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0021 0.0024 0.0076
Entamoeba histolytica deoxycytidyl transferase, putative 0.0037 0.0097 0.0305
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0044 0.0127 0.0127
Loa Loa (eye worm) tubulin beta-1 chain 0.0343 0.1474 0.2592
Echinococcus multilocularis pyruvate kinase 0.0027 0.0049 0.0049
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0063 0.0212 0.067
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0269 0.114 0.2004
Mycobacterium ulcerans hypothetical protein 0.0039 0.0104 0.0463
Loa Loa (eye worm) alpha-tubulin 0.0281 0.1195 0.2101
Brugia malayi Tubulin gamma chain 0.0206 0.0859 0.151
Trypanosoma cruzi cysteine peptidase, putative 0.0046 0.0134 0.0424
Loa Loa (eye worm) tubulin beta-2A chain 0.0343 0.1474 0.2592
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0192 0.0676
Echinococcus multilocularis smad 0.0034 0.0083 0.0083
Brugia malayi MH1 domain containing protein 0.0019 0.0014 0.0025
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0024 0.0085
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0449 0.1581
Trichomonas vaginalis tubulin epsilon chain, putative 0.0343 0.1474 0.5196
Schistosoma mansoni laminin gamma-3 chain 0.0076 0.0273 0.0435
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0039 0.0104 0.0463
Brugia malayi Cadherin domain containing protein 0.0076 0.0273 0.048
Trypanosoma cruzi DNA topoisomerase II, putative 0.0569 0.2491 0.7876
Brugia malayi MH2 domain containing protein 0.0502 0.2189 0.3848
Loa Loa (eye worm) hypothetical protein 0.0108 0.0415 0.073
Schistosoma mansoni tubulin subunit beta 0.0343 0.1474 0.2348
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0076 0.0273 0.0435
Schistosoma mansoni chromobox protein 0.005 0.0153 0.0244
Loa Loa (eye worm) phosphatidylinositol 3 0.0087 0.032 0.0562
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0045 0.0141
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0014 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.022 0.0773
Echinococcus granulosus tubulin epsilon chain 0.0206 0.0859 0.1368
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0034 0.0082 0.0348
Loa Loa (eye worm) hypothetical protein 0.0104 0.0399 0.0701
Trypanosoma brucei heat shock protein, putative 0.0034 0.0082 0.0258
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.014 0.0491
Trypanosoma cruzi hexokinase, putative 0.0718 0.3163 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.006 0.0211
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0104 0.0399 0.0635
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0104 0.0399 0.0701
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Loa Loa (eye worm) hypothetical protein 0.0395 0.1707 0.3001
Trypanosoma cruzi beta tubulin, putative 0.0343 0.1474 0.4661
Brugia malayi isocitrate dehydrogenase 0.0079 0.0287 0.0504
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Leishmania major carbonic anhydrase-like protein 0.0588 0.2578 0.8152
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0024 0.0085
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0003 0.0005
Echinococcus granulosus tubulin alpha chain 0.0281 0.1195 0.1904
Leishmania major cathepsin L-like protease 0.0046 0.0134 0.0424
Brugia malayi Smad1 0.0034 0.0083 0.0146
Brugia malayi prostaglandin transporter 0.0022 0.0029 0.0052
Loa Loa (eye worm) hypothetical protein 0.0393 0.1701 0.299
Loa Loa (eye worm) hypothetical protein 0.0108 0.0415 0.073
Echinococcus multilocularis tubulin subunit beta 0.0343 0.1474 0.1474
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0038 0.0099 0.0433
Toxoplasma gondii exonuclease III APE 0.0064 0.0217 0.0685
Schistosoma mansoni tubulin subunit delta 0.009 0.0333 0.053
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Onchocerca volvulus 0.0718 0.3163 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0104 0.0463
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0029 0.006 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.022 0.0773
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0038 0.0099 0.0433
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0038 0.0099 0.0433
Onchocerca volvulus 0.059 0.2588 0.8184
Trypanosoma brucei beta tubulin 0.0343 0.1474 0.4661
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0276 0.1174 0.1174
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0025
Echinococcus multilocularis tubulin delta chain 0.009 0.0333 0.0333
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0081 0.0296 0.0296
Plasmodium falciparum metacaspase 1 0.0021 0.0024 0.0077
Schistosoma mansoni lamin 0.0132 0.0523 0.0832
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0034 0.0082 0.0258
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0276 0.1174 0.187
Loa Loa (eye worm) hypothetical protein 0.1279 0.5689 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0079 0.0287 0.0456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.014 0.0492
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0191 0.0792 0.2789
Entamoeba histolytica acyl-coA synthetase, putative 0.0019 0.0014 0.0044
Loa Loa (eye worm) hypothetical protein 0.0393 0.1701 0.299
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Echinococcus multilocularis protein dispatched 1 0.0109 0.0421 0.0421
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0038 0.0099 0.0433
Leishmania major alpha tubulin 0.0281 0.1195 0.3779
Leishmania major hypothetical protein, conserved 0.0124 0.0486 0.1536
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0038 0.0099 0.0433
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0055 0.0179 0.0179
Onchocerca volvulus 0.0117 0.0456 0.144
Trichomonas vaginalis tubulin epsilon chain, putative 0.0281 0.1195 0.4213
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Leishmania major alpha tubulin 0.0281 0.1195 0.3779
Toxoplasma gondii alpha tubulin TUBA1 0.0281 0.1195 0.3779
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0079 0.0287 0.0905
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0087 0.032 0.0562
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0063 0.0212 0.067
Brugia malayi glutaminase DH11.1 0.0195 0.0809 0.1421
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.019 0.0334
Plasmodium vivax tubulin gamma chain, putative 0.0206 0.0859 0.2717
Loa Loa (eye worm) BEN-1 protein 0.0343 0.1474 0.2592
Brugia malayi Hexokinase family protein 0.0222 0.093 0.1634
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.0314 0.0314
Schistosoma mansoni hypothetical protein 0.0056 0.0182 0.0289
Brugia malayi Calcium binding EGF domain containing protein 0.0076 0.0273 0.048
Schistosoma mansoni DNA polymerase eta 0.0037 0.0097 0.0154
Schistosoma mansoni chromobox protein 0.005 0.0153 0.0244
Brugia malayi Niemann-Pick C1 protein precursor 0.0223 0.0933 0.164
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0055 0.0192
Schistosoma mansoni caspase-3 (C14 family) 0.0079 0.0286 0.0455
Leishmania major alpha tubulin 0.0281 0.1195 0.3779
Echinococcus granulosus Solute carrier organic anion transporter family 0.0022 0.0029 0.0047
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0588 0.2578 0.4532
Onchocerca volvulus 0.0646 0.2838 0.8972
Loa Loa (eye worm) hypothetical protein 0.0104 0.0399 0.0701
Giardia lamblia Beta tubulin 0.0343 0.1474 0.5624
Plasmodium vivax delta tubulin, putative 0.009 0.0333 0.1053
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0038 0.0099 0.0433
Toxoplasma gondii isocitrate dehydrogenase 0.0079 0.0287 0.0905
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.009 0.0333 0.1052
Brugia malayi hypothetical protein 0.0046 0.0138 0.0242
Echinococcus granulosus tubulin alpha chain 0.0281 0.1195 0.1904
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0104 0.0399 0.0399
Schistosoma mansoni tubulin subunit alpha 0.0281 0.1195 0.1904
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0034 0.0082 0.0348
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0064 0.0217 0.0686
Trichomonas vaginalis receptor histidine kinase, putative 0.0034 0.0082 0.0288
Leishmania major alpha tubulin 0.0281 0.1195 0.3779
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0104 0.0399 0.0635
Echinococcus granulosus fibropellin Ia 0.0076 0.0273 0.0435
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.009 0.0333 0.1538
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0048 0.0151
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0058 0.0192 0.0676
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0034 0.0118
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0095 0.0357 0.0569
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0034 0.0082 0.0348
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.006 0.0211
Loa Loa (eye worm) hypothetical protein 0.0104 0.0399 0.0701
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0025
Mycobacterium ulcerans putative regultory protein 0.0034 0.0082 0.0348
Echinococcus multilocularis musashi 0.0132 0.0523 0.0523
Loa Loa (eye worm) hypothetical protein 0.0046 0.0138 0.0242
Echinococcus multilocularis chromobox protein 1 0.005 0.0153 0.0153
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0395 0.1707 0.3001
Brugia malayi intermediate filament protein 0.0132 0.0523 0.0919
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0034 0.0082 0.0348
Loa Loa (eye worm) hypothetical protein 0.0039 0.0104 0.0183
Leishmania major zeta tubulin, putative 0.009 0.0333 0.1052
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0087 0.032 0.032
Loa Loa (eye worm) animal heme peroxidase 0.059 0.2588 0.455
Loa Loa (eye worm) animal heme peroxidase 0.059 0.2588 0.455
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0064 0.0217 0.0685
Onchocerca volvulus 0.0114 0.0443 0.1399
Loa Loa (eye worm) hypothetical protein 0.049 0.2135 0.3752
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.0097 0.0424
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0049 0.0149 0.0149
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0038 0.0099 0.0311
Echinococcus multilocularis tubulin alpha chain 0.0281 0.1195 0.1195
Echinococcus granulosus tubulin alpha 1C chain 0.0281 0.1195 0.1904
Brugia malayi Tubulin beta-1 chain 0.0343 0.1474 0.2592
Echinococcus multilocularis heat shock protein 0.0034 0.0082 0.0082
Trichomonas vaginalis adenylate cyclase, putative 0.0058 0.0192 0.0676
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0046 0.0134 0.0424
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0335 0.1436 0.4541
Brugia malayi hypothetical protein 0.0353 0.1519 0.267
Echinococcus granulosus neuropeptide s receptor 0.0948 0.4201 0.669
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0104 0.0399 0.0635
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0092 0.0345 0.1599
Echinococcus granulosus voltage gated potassium channel 0.0019 0.0016 0.0025
Trypanosoma brucei metacaspase MCA3 0.0021 0.0024 0.0076
Plasmodium falciparum carbonic anhydrase 0.0395 0.1707 0.5398
Onchocerca volvulus 0.0016 0.0002 0.0007
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0064 0.0217 0.0217
Schistosoma mansoni single-minded 0.0156 0.0634 0.101
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.019 0.0334
Onchocerca volvulus Huntingtin homolog 0.0139 0.0554 0.1751
Plasmodium falciparum tubulin epsilon chain, putative 0.0206 0.0859 0.2717
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0085
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0451 0.1959 0.6149
Schistosoma mansoni zinc finger protein 0.0046 0.0138 0.022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0104 0.0399 0.0701
Brugia malayi Nuclear hormone receptor E75 0.0046 0.0138 0.0242
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0104 0.0399 0.0701
Loa Loa (eye worm) hypothetical protein 0.0046 0.0138 0.0242
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0632 0.2774 0.4876
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0104 0.0399 0.0701
Echinococcus granulosus tubulin delta chain 0.009 0.0333 0.053
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Trypanosoma brucei epsilon tubulin 0.0206 0.0859 0.2716
Brugia malayi Isocitrate dehydrogenase 0.0079 0.0287 0.0504
Echinococcus granulosus expressed conserved protein 0.0209 0.0872 0.1389
Onchocerca volvulus 0.0076 0.0273 0.0863
Plasmodium vivax tubulin alpha chain, putative 0.0281 0.1195 0.3779
Schistosoma mansoni alpha tubulin 0.0281 0.1195 0.1904
Schistosoma mansoni hypothetical protein 0.0076 0.0273 0.0435
Brugia malayi Delta serrate ligand family protein 0.0076 0.0273 0.048
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0064 0.0216 0.0216
Onchocerca volvulus 0.0075 0.0265 0.0839
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0038 0.0099 0.0433
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0034 0.0082 0.0348
Echinococcus multilocularis carbonic anhydrase II 0.0588 0.2578 0.2578
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0069 0.0239 0.0754
Echinococcus granulosus hexokinase type 2 0.0718 0.3163 0.5037
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0046 0.0135 0.0238
Echinococcus granulosus geminin 0.1256 0.5586 0.8895
Plasmodium falciparum alpha tubulin 2 0.0281 0.1195 0.3779
Plasmodium falciparum ataxin-2 like protein, putative 0.0124 0.0486 0.1537
Schistosoma mansoni nuclear hormone receptor 0.0104 0.0399 0.0635
Trichomonas vaginalis chromobox protein, putative 0.003 0.0064 0.0226
Plasmodium falciparum pyruvate kinase 0.0027 0.0049 0.0155
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0082 0.0258
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Toxoplasma gondii hypothetical protein 0.0039 0.0104 0.0328
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0016 0.0003 0.0009
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0114 0.0442 0.1295
Onchocerca volvulus Pyruvate kinase homolog 0.0027 0.0049 0.0155
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0046 0.0135 0.0426
Echinococcus multilocularis ecdysone induced protein 78C 0.0104 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0097 0.0424
Loa Loa (eye worm) CYP4Cod1 0.009 0.0334 0.0588
Brugia malayi Tubulin beta chain 0.009 0.0333 0.0585
Loa Loa (eye worm) hypothetical protein 0.0046 0.0138 0.0242
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0069 0.0239 0.038
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.014 0.0492
Trichomonas vaginalis tubulin, putative 0.009 0.0333 0.1173
Brugia malayi hypothetical protein 0.0056 0.0182 0.0319
Echinococcus multilocularis tumor protein p63 0.0382 0.1652 0.1652
Schistosoma mansoni nuclear receptor 0.0046 0.0138 0.022
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0046 0.0138 0.022
Schistosoma mansoni alpha tubulin 0.0281 0.1195 0.1904
Chlamydia trachomatis endonuclease IV 0.0148 0.0595 0.2902
Plasmodium vivax tubulin alpha chain, putative 0.0281 0.1195 0.3779
Loa Loa (eye worm) transcription factor SMAD2 0.0502 0.2189 0.3848
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0046 0.0134 0.0424
Entamoeba histolytica acyl-CoA synthetase, putative 0.0019 0.0014 0.0044
Schistosoma mansoni tubulin subunit alpha 0.0281 0.1195 0.1904
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Echinococcus multilocularis nuclear receptor nhr 48 0.0046 0.0138 0.0138
Onchocerca volvulus 0.0022 0.0029 0.0093
Onchocerca volvulus 0.0099 0.0373 0.1179
Echinococcus granulosus neurogenic locus notch protein 0.0076 0.0273 0.0435
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0115 0.0449 0.1418
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0024 0.0085
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0034 0.0082 0.0259
Loa Loa (eye worm) RecQ helicase 0.0016 0 0.0001
Mycobacterium ulcerans hypothetical protein 0.0127 0.05 0.2498
Schistosoma mansoni hypothetical protein 0.0038 0.0099 0.0157
Schistosoma mansoni hypothetical protein 0.0092 0.0344 0.0549
Trichomonas vaginalis ap endonuclease, putative 0.0064 0.0217 0.0763
Loa Loa (eye worm) hypothetical protein 0.0121 0.0475 0.0835
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0037 0.0097 0.0154
Schistosoma mansoni cytochrome P450 0.0038 0.0099 0.0157
Trichomonas vaginalis sensor histidine kinase, putative 0.0034 0.0082 0.0288
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0046 0.0134 0.0424
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0038 0.0099 0.0433
Echinococcus multilocularis neurogenic locus notch protein 0.0076 0.0273 0.0273
Plasmodium falciparum alpha tubulin 1 0.0281 0.1195 0.3779
Onchocerca volvulus 0.0132 0.0523 0.1652
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.036 0.1268
Trichomonas vaginalis tubulin beta chain, putative 0.0117 0.0456 0.1604
Leishmania major beta tubulin 0.0343 0.1474 0.4661
Brugia malayi Heterochromatin protein 1 0.005 0.0153 0.027
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0079 0.0287 0.0906
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.024 0.0844
Giardia lamblia Epsilon tubulin 0.009 0.0333 0.1269
Loa Loa (eye worm) notch protein 0.0076 0.0273 0.048
Brugia malayi Hexokinase family protein 0.045 0.1958 0.3441
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0632 0.2774 0.4418
Echinococcus multilocularis tubulin alpha chain 0.0281 0.1195 0.1195
Brugia malayi hypothetical protein 0.0022 0.0029 0.0052
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0025
Brugia malayi Cadherin domain containing protein 0.0076 0.0273 0.048
Echinococcus granulosus mitogen activated protein kinase 0.0115 0.0449 0.0715
Plasmodium vivax DNA topoisomerase II, putative 0.0632 0.2774 0.8771
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0046 0.0134 0.0424
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0082 0.0258
Brugia malayi Tubulin alpha-2 chain 0.0281 0.1195 0.2101
Schistosoma mansoni peroxidasin 0.059 0.2588 0.4122
Schistosoma mansoni tubulin subunit beta 0.0343 0.1474 0.2348
Onchocerca volvulus 0.059 0.2588 0.8184
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0037 0.0398
Echinococcus granulosus protein jagged 1 0.0076 0.0273 0.0435
Echinococcus multilocularis Tubulin beta 2C chain 0.0343 0.1474 0.1474
Trichomonas vaginalis endoplasmin, putative 0.0034 0.0082 0.0288
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0029 0.006 0.0189
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0104 0.0399 0.0635
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0052
Schistosoma mansoni hypothetical protein 0.0055 0.0179 0.0285
Brugia malayi EGF-like domain containing protein 0.0076 0.0273 0.048
Brugia malayi EGF-like domain containing protein 0.0076 0.0273 0.048
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0026 0.0048 0.0151
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0029 0.006 0.0189
Loa Loa (eye worm) cytochrome P450 family protein 0.009 0.0334 0.0588
Toxoplasma gondii beta tubulin 0.0343 0.1474 0.4661
Toxoplasma gondii hypothetical protein 0.0016 0.0002 0.0006
Loa Loa (eye worm) pyruvate kinase 0.0027 0.0049 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.022 0.0773
Brugia malayi MH2 domain containing protein 0.0034 0.0083 0.0146
Echinococcus multilocularis tubulin alpha 1C chain 0.0281 0.1195 0.1195
Echinococcus granulosus tubulin alpha 1C chain 0.0281 0.1195 0.1904
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0037 0.0117
Echinococcus granulosus Protein patched homolog 1 0.0096 0.036 0.0573
Leishmania major heat shock protein 83-1 0.0034 0.0082 0.0258
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0046 0.0135 0.0135
Trypanosoma cruzi DNA topoisomerase II, putative 0.0569 0.2491 0.7876
Entamoeba histolytica hypothetical protein 0.0276 0.1174 0.3711
Onchocerca volvulus 0.0718 0.3163 1
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0569 0.2491 0.7876
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0016 0 0.0001
Leishmania major delta tubulin, putative 0.009 0.0333 0.1052
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0052
Echinococcus granulosus segment polarity protein dishevelled 0.0016 0.0002 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0045 0.0141
Brugia malayi DIX domain containing protein 0.0016 0.0002 0.0004
Loa Loa (eye worm) tubulin alpha 2 0.0191 0.0792 0.1391
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0239 0.038
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0085
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0588 0.2578 0.8152
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0037 0.0118
Brugia malayi MAP kinase sur-1 0.0115 0.0449 0.0789
Trypanosoma cruzi PAB1-binding protein , putative 0.0124 0.0486 0.1536
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0138 0.022
Brugia malayi ecdysteroid receptor 0.0104 0.0399 0.0701
Echinococcus multilocularis tubulin subunit TubB 0.0281 0.1195 0.1195
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0097 0.0305
Trypanosoma brucei heat shock protein, putative 0.0034 0.0082 0.0258
Echinococcus multilocularis ubiquitin specific protease 41 0.0026 0.0048 0.0048
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0056 0.0182 0.0319
Loa Loa (eye worm) TOPoisomerase family member 0.0632 0.2774 0.4876
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Loa Loa (eye worm) hypothetical protein 0.0076 0.0273 0.048
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0395 0.1707 0.3001
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0049 0.0149 0.0262
Brugia malayi hypothetical protein 0.0016 0.0002 0.0004
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0038 0.0099 0.0433
Onchocerca volvulus 0.0085 0.0314 0.0993
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0087 0.032 0.1009
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0104 0.0399 0.1261
Schistosoma mansoni lozenge 0.0044 0.0129 0.0205
Trypanosoma brucei tubulin delta chain 0.009 0.0333 0.1052
Onchocerca volvulus 0.0022 0.0029 0.0093
Loa Loa (eye worm) hypothetical protein 0.0104 0.0399 0.0701
Trichomonas vaginalis tubulin gamma chain, putative 0.009 0.0333 0.1173
Plasmodium vivax DNA gyrase subunit B, putative 0.0451 0.1959 0.6194
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0064 0.0217 0.0686
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0056 0.0182 0.0289
Schistosoma mansoni smad1 5 8 and 0.0034 0.0083 0.0132
Echinococcus granulosus neurogenic locus notch protein 0.0076 0.0273 0.0435
Loa Loa (eye worm) hypothetical protein 0.059 0.2588 0.455
Echinococcus multilocularis Tubulin beta 2C chain 0.0343 0.1474 0.1474
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0651 0.2862 0.9048
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0021 0.0024 0.0043
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0034 0.0082 0.0288
Echinococcus granulosus Pleckstrin G protein interacting region 0.0016 0.0002 0.0003
Mycobacterium ulcerans pyruvate kinase 0.0027 0.0049 0.0178
Trypanosoma brucei heat shock protein, putative 0.0034 0.0082 0.0258
Trichomonas vaginalis chromobox protein, putative 0.003 0.0064 0.0226
Trichomonas vaginalis tubulin beta chain, putative 0.0281 0.1195 0.4213
Echinococcus granulosus neurogenic locus protein delta 0.0076 0.0273 0.0435
Leishmania major mitochondrial DNA polymerase beta 0.0241 0.1013 0.3203
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0034 0.0082 0.0257
Brugia malayi Blistered cuticle protein 3 0.059 0.2588 0.455
Onchocerca volvulus Peroxidasin homolog 0.059 0.2588 0.8184
Loa Loa (eye worm) blistered cuticle protein 3 0.059 0.2588 0.455
Mycobacterium ulcerans DNA gyrase subunit A 0.0114 0.0442 0.22
Echinococcus multilocularis aryl hydrocarbon receptor 0.0114 0.0444 0.0444
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0042 0.0117 0.0368
Loa Loa (eye worm) hypothetical protein 0.0052 0.0165 0.029
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0144

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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