Detailed information for compound 159807

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 457.049 | Formula: C30H33ClN2
  • H donors: 1 H acceptors: 0 LogP: 6.99 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccccc1CNC1C2CC3N([C@H]1C(c1ccccc1)c1ccccc1)C(C2)CCC3
  • InChi: 1S/C30H33ClN2/c31-27-17-8-7-14-23(27)20-32-29-24-18-25-15-9-16-26(19-24)33(25)30(29)28(21-10-3-1-4-11-21)22-12-5-2-6-13-22/h1-8,10-14,17,24-26,28-30,32H,9,15-16,18-20H2/t24?,25?,26?,29?,30-/m0/s1
  • InChiKey: HTQPNCOATOPAJK-ICQJPXRGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens tachykinin receptor 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K04224 tachykinin receptor 3, putative Get druggable targets OG5_137770 All targets in OG5_137770
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Loa Loa (eye worm) PHD-finger family protein 0.0048 0.002 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0722 0.0458 0.6106
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0156 0.0091 0.0845
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.031 0.0191 0.467
Loa Loa (eye worm) hypothetical protein 0.0448 0.028 0.2618
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0006 0.0313
Onchocerca volvulus 0.0232 0.014 0.872
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0051 0.0023 0.031
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0021 0.0251
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.003
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0025 0.0006 0.032
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Loa Loa (eye worm) hypothetical protein 0.0032 0.0011 0.0095
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.0026 0.0355
Toxoplasma gondii PHD-finger domain-containing protein 0.0048 0.002 0.0276
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Brugia malayi RNA recognition motif domain containing protein 0.0223 0.0135 0.1755
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0052
Echinococcus granulosus neutral alpha glucosidase AB 0.0051 0.0023 0.0022
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.0067 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0022 0.0004 0.009
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0067 0.0881
Schistosoma mansoni hypothetical protein 0.0094 0.0051 0.0468
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0044 0.0018 0.0971
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.014 0.1302
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0073 0.0037 0.0502
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0126 0.0072 0.0071
Mycobacterium ulcerans beta-lactamase 0.0101 0.0055 0.3052
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0019 0.0169
Onchocerca volvulus 0.0101 0.0055 0.3358
Giardia lamblia NADH oxidase lateral transfer candidate 0.0047 0.002 0.0243
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Chlamydia trachomatis endonuclease IV 0.0084 0.0044 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0064
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Loa Loa (eye worm) hypothetical protein 0.0094 0.0051 0.0468
Loa Loa (eye worm) importin-beta domain-containing protein 0.0029 0.0009 0.0077
Loa Loa (eye worm) hypothetical protein 0.0075 0.0038 0.0354
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0126 0.0072 0.0071
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0015 0.0171
Brugia malayi Cytochrome P450 family protein 0.0071 0.0036 0.0453
Mycobacterium tuberculosis Putative ferredoxin reductase 0.031 0.0191 0.467
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Trichomonas vaginalis glutathione reductase, putative 0.0047 0.002 0.0243
Brugia malayi RNA binding protein 0.0223 0.0135 0.1755
Echinococcus granulosus neuropeptide FF receptor 2 0.0126 0.0072 0.0071
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0044 0.0018 0.0971
Leishmania major phosphatidylinositol 3-kinase, putative 0.1139 0.0729 0.2004
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0101 0.0055 0.0512
Loa Loa (eye worm) G-protein coupled receptor 0.0126 0.0072 0.0665
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Echinococcus granulosus dro:myosuppressin receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0004 0.0205
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Leishmania major phosphatidylinositol 3-related kinase, putative 0.115 0.0737 0.2023
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.049 0.0308 0.0307
Echinococcus multilocularis serotonin receptor 0.0126 0.0072 0.0071
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0021 0.0281
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0019 0.0002 0.0013
Brugia malayi Melatonin receptor type 1A 0.0126 0.0072 0.0925
Mycobacterium tuberculosis Conserved hypothetical protein 0.0232 0.014 0.342
Echinococcus granulosus Chromo domain 0.0025 0.0006 0.0005
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0004 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0026 0.0007 0.0073
Plasmodium falciparum glutathione reductase 0.0136 0.0078 0.447
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0044 0.0018 0.0427
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0073 0.0037 0.0036
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0448 0.028 0.0279
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0026 0.0007 0.0058
Echinococcus granulosus cpg binding protein 0.0117 0.0066 0.0065
Brugia malayi neuropeptide F receptor 0.0126 0.0072 0.0925
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0044 0.0018 0.0427
Toxoplasma gondii NAC domain-containing protein 0.0022 0.0004 0.0056
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0026 0.0007 0.0058
Schistosoma mansoni ap endonuclease 0.0039 0.0015 0.0136
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0015 0.0184
Trypanosoma brucei trypanothione reductase 0.0136 0.0078 0.1024
Loa Loa (eye worm) hypothetical protein 0.0072 0.0036 0.0337
Echinococcus granulosus G protein coupled receptor 139 0.0126 0.0072 0.0071
Onchocerca volvulus Neuropeptide F receptor homolog 0.0126 0.0072 0.4394
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0664 0.0421 0.3932
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Echinococcus multilocularis 0.0232 0.014 0.0139
Loa Loa (eye worm) phosphatidylinositol 3 0.0117 0.0065 0.0608
Leishmania major basic transcription factor 3a, putative 0.0022 0.0004 0.0008
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0024 0.1372
Brugia malayi cytoplasmic intermediate filament protein 0.0072 0.0036 0.0464
Trypanosoma cruzi FHA domain containing protein, putative 0.0019 0.0002 0.0002
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.005 0.0022 0.0201
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0026 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Schistosoma mansoni myosin xvIII 0.0126 0.0072 0.0664
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0013 0.0013
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0017 0.0197
Schistosoma mansoni peptidase Clp (S14 family) 0.0073 0.0037 0.0343
Plasmodium falciparum transportin 0.0029 0.0009 0.0478
Echinococcus multilocularis replication factor c subunit 1 0.0019 0.0002 0.0001
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0283 0.0174 0.0173
Trypanosoma brucei target of rapamycin kinase 3, putative 0.116 0.0743 0.9919
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0046 0.0591
Trichomonas vaginalis PIKK family atypical protein kinase 0.1139 0.0729 0.9737
Trypanosoma brucei polo-like protein kinase 0.0176 0.0104 0.1368
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0174 0.2305
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0629 0.0398 0.5304
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Brugia malayi hypothetical protein 0.0034 0.0012 0.0143
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0743 0.0472 0.6288
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0015 0.0175
Echinococcus granulosus zinc finger protein 0.003 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Echinococcus multilocularis snurportin 1 0.1663 0.1069 0.1069
Brugia malayi Associated with TFs and helicases family protein 0.0025 0.0006 0.0063
Echinococcus granulosus 7tm_1 domain containing protein 0.0126 0.0072 0.0071
Entamoeba histolytica hypothetical protein 0.0068 0.0034 0.0424
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0104 0.0965
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.005 0.0022 0.0266
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0019 0.0002 0.0028
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0044 0.0018 0.0427
Schistosoma mansoni cpg binding protein 0.0117 0.0066 0.0609
Schistosoma mansoni hypothetical protein 0.0094 0.0051 0.0468
Loa Loa (eye worm) CXXC zinc finger family protein 0.0109 0.006 0.056
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0126 0.0072 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.1139 0.0729 0.9737
Schistosoma mansoni ran 0.0091 0.0049 0.0453
Echinococcus granulosus neuropeptides capa receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Trichomonas vaginalis D-aminoacylase, putative 0.0101 0.0055 0.0711
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0283 0.0174 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0015 0.3713
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.0216 0.2861
Schistosoma mansoni rab6-interacting 0.0022 0.0004 0.0029
Echinococcus granulosus replication factor c subunit 1 0.0019 0.0002 0.0001
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.117 0.0749 1
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0101 0.0055 0.0511
Brugia malayi topoisomerase 0.0019 0.0002 0.0013
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0007 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0026 0.0007 0.0073
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.031 0.0191 0.467
Loa Loa (eye worm) beta-lactamase 0.0101 0.0055 0.0512
Brugia malayi phosphofructokinase 0.0119 0.0067 0.0868
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni hypothetical protein 0.0126 0.0072 0.0664
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0126 0.0072 0.0925
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0126 0.0072 0.0664
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.0026 0.0025
Mycobacterium tuberculosis Conserved protein 0.0101 0.0055 0.1341
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Schistosoma mansoni intermediate filament proteins 0.0135 0.0077 0.0715
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0649 0.0411 0.1177
Brugia malayi RE15519p 0.0126 0.0072 0.0925
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0016 0.0015
Brugia malayi hypothetical protein 0.0178 0.0105 0.1369
Onchocerca volvulus 0.0126 0.0072 0.4394
Onchocerca volvulus 0.0126 0.0072 0.4394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0232 0.014 0.1846
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0001 0.0004
Trichomonas vaginalis ran, putative 0.0091 0.0049 0.0628
Plasmodium vivax heterochromatin protein 1, putative 0.0025 0.0006 0.0331
Trypanosoma cruzi polo-like protein kinase, putative 0.0176 0.0104 0.0294
Onchocerca volvulus Huntingtin homolog 0.0178 0.0105 0.6531
Trichomonas vaginalis glutaminase, putative 0.0293 0.018 0.2377
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Echinococcus granulosus neuropeptide receptor 0.0126 0.0072 0.0071
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0174 0.0495
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0024 0.1372
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0126 0.0072 0.0071
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0084 0.0044 0.1999
Loa Loa (eye worm) ICD-1 protein 0.0022 0.0004 0.0034
Leishmania major hypothetical protein, conserved 0.0029 0.0009 0.002
Schistosoma mansoni hypothetical protein 0.049 0.0308 0.2875
Entamoeba histolytica hypothetical protein 0.0232 0.014 0.1846
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.049 0.0308 0.4094
Echinococcus granulosus serine protein kinase ATM 0.0664 0.0421 0.042
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0008 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Onchocerca volvulus 0.0022 0.0004 0.0132
Onchocerca volvulus 0.0126 0.0072 0.4394
Echinococcus multilocularis importin 5 0.0029 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0418 0.0261 0.3464
Brugia malayi Probable ClpP-like protease 0.0073 0.0037 0.0474
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0026 0.0007 0.0073
Onchocerca volvulus Huntingtin homolog 0.0178 0.0105 0.6531
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0062 0.003 0.0278
Schistosoma mansoni steroid hormone receptor ad4bp 0.0026 0.0007 0.0057
Onchocerca volvulus Alhambra homolog 0.0048 0.002 0.1165
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0067 0.0624
Echinococcus multilocularis g protein coupled receptor 0.0126 0.0072 0.0071
Entamoeba histolytica hypothetical protein 0.0068 0.0034 0.0424
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Onchocerca volvulus 0.0034 0.0011 0.0595
Loa Loa (eye worm) hypothetical protein 0.0124 0.007 0.0651
Schistosoma mansoni hypothetical protein 0.0044 0.0018 0.0162
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0005 0.0053
Loa Loa (eye worm) melatonin receptor type 1A 0.0126 0.0072 0.0665
Schistosoma mansoni lipoxygenase 0.0022 0.0004 0.0029
Echinococcus granulosus histone acetyltransferase KAT2B 0.0151 0.0088 0.0087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0664 0.0421 0.5606
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0021 0.0251
Loa Loa (eye worm) hypothetical protein 0.0121 0.0068 0.0631
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3846 0.2487 0.2487
Echinococcus multilocularis neuropeptide s receptor 0.0423 0.0264 0.0263
Schistosoma mansoni hypothetical protein 0.0025 0.0006 0.005
Brugia malayi photoreceptor-specific nuclear receptor 0.0026 0.0007 0.0073
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0005 0.0042
Loa Loa (eye worm) hypothetical protein 0.0045 0.0019 0.0174
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0348 0.0216 0.2861
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0042
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0047 0.002 0.0052
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0283 0.0174 0.2266
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Onchocerca volvulus 0.0109 0.006 0.3684
Brugia malayi AKH receptor 0.0126 0.0072 0.0925
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0002 0.0013
Schistosoma mansoni jumonji domain containing protein 0.0124 0.007 0.0649
Brugia malayi Serotonin receptor 0.0126 0.0072 0.0925
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0047 0.002 0.0019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0007 0.0073
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0026 0.0007 0.0057
Loa Loa (eye worm) hypothetical protein 0.0073 0.0037 0.0344
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0101 0.0055 0.3052
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0433 0.027 0.0773
Brugia malayi Serotonin receptor 0.0126 0.0072 0.0925
Trichomonas vaginalis PIKK family atypical protein kinase 0.1139 0.0729 0.9737
Schistosoma mansoni alpha-glucosidase 0.0199 0.0119 0.111
Loa Loa (eye worm) hypothetical protein 0.0135 0.0077 0.0716
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0067 0.0872
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0126 0.0072 0.0665
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0026 0.0007 0.0057
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0044 0.2531
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.5396
Echinococcus multilocularis ecdysone induced protein 78C 0.0026 0.0007 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0047 0.002 0.5162
Leishmania major phosphatidylinositol 3-kinase, putative 0.0283 0.0174 0.0474
Echinococcus granulosus orexin receptor type 2 0.0126 0.0072 0.0071
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0047 0.002 0.0252
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0101 0.0055 0.0155
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0035 0.0012 0.0011
Echinococcus granulosus transcription factor btf3 0.0022 0.0004 0.0003
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0032 0.0031
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0126 0.0072 0.0665
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0004 0.0123
Onchocerca volvulus 0.0126 0.0072 0.4394
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0126 0.0072 0.4394
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus translational activator gcn1 0.0029 0.0009 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0026 0.0316
Echinococcus granulosus thioredoxin glutathione reductase 0.0136 0.0078 0.0077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus granulosus GTP binding nuclear protein Ran 0.0091 0.0049 0.0048
Echinococcus granulosus cytochrome P450 2K1 0.0044 0.0018 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.1151 0.0737 0.9838
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0047 0.002 0.1101
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0099 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.005 0.0022 0.0201
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0004 0.0205
Echinococcus granulosus alpha 1A adrenergic receptor 0.0126 0.0072 0.0071
Plasmodium vivax basic transcription factor 3b, putative 0.0022 0.0004 0.0231
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Trichomonas vaginalis PIKK family atypical protein kinase 0.066 0.0418 0.5571
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0047 0.002 0.0251
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0348 0.0216 0.2861
Toxoplasma gondii cytochrome p450 superfamily protein 0.0044 0.0018 0.0241
Schistosoma mansoni hypothetical protein 0.0094 0.0051 0.0468
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Brugia malayi PHD-finger family protein 0.0024 0.0005 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0629 0.0398 0.5304
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0008 0.0007
Schistosoma mansoni hypothetical protein 0.0232 0.014 0.1304
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0232 0.014 0.0139
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0126 0.0072 0.0664
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0047 0.0608
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Brugia malayi beta-lactamase 0.0101 0.0055 0.071
Toxoplasma gondii target of rapamycin (TOR), putative 0.1158 0.0742 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0026 0.0007 0.0006
Schistosoma mansoni transcription factor btf3 0.0022 0.0004 0.0034
Schistosoma mansoni chromosome transmission fidelity factor 0.0019 0.0002 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.117 0.0749 1
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0022 0.0058
Loa Loa (eye worm) RecQ helicase 0.0024 0.0005 0.0044
Brugia malayi MAP kinase sur-1 0.0057 0.0026 0.0331
Trichomonas vaginalis set domain proteins, putative 0.0263 0.016 0.2117
Schistosoma mansoni hypothetical protein 0.0094 0.0051 0.0468
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0026 0.0325
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0232 0.014 0.1824
Trypanosoma cruzi major cysteine proteinase, putative 0.0039 0.0015 0.0038
Toxoplasma gondii FATC domain-containing protein 0.0664 0.0421 0.5675
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Brugia malayi jmjC domain containing protein 0.0156 0.0091 0.1177
Echinococcus granulosus nibrin 0.0019 0.0002 0.0001
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0073 0.0037 0.2136
Echinococcus multilocularis g-protein coupled receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0033 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Brugia malayi nuclear receptor NHR-88 0.0026 0.0007 0.0073
Leishmania major cathepsin L-like protease 0.0049 0.0022 0.0056
Echinococcus granulosus chromobox protein 1 0.0089 0.0047 0.0047
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0014 0.0166
Echinococcus granulosus biogenic amine 5HT receptor 0.0126 0.0072 0.0071
Mycobacterium leprae Probable lipase LipE 0.0101 0.0055 0.2512
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0006 0.0331
Brugia malayi FAT domain containing protein 0.049 0.0308 0.4029
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0348 0.0216 0.2861
Brugia malayi beta-lactamase family protein 0.0101 0.0055 0.071
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0034
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0026 0.0072
Leishmania major hypothetical protein, conserved 0.0053 0.0024 0.0063
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0015 0.0845
Echinococcus multilocularis neuropeptides capa receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) neuropeptide F receptor 0.0126 0.0072 0.0665
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.0398
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.117 0.0749 0.2058
Onchocerca volvulus 0.0101 0.0055 0.3358
Echinococcus granulosus intermediate filament protein 0.0135 0.0077 0.0076
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0044 0.0018 0.0971
Echinococcus granulosus importin 5 0.0029 0.0009 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0004 0.0205
Echinococcus granulosus neuropeptide receptor A26 0.0423 0.0264 0.0263
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Entamoeba histolytica hypothetical protein 0.0664 0.0421 0.5606
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.005 0.0022 0.0201
Trichomonas vaginalis mercuric reductase, putative 0.0047 0.002 0.0243
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0185 0.011 0.6818
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0232 0.014 0.0139
Mycobacterium ulcerans epimerase 0.0022 0.0004 0.0197
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Brugia malayi Bromodomain containing protein 0.0087 0.0046 0.0587
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0108 0.1004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0108 0.1003
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0232 0.014 0.8057
Toxoplasma gondii hypothetical protein 0.0025 0.0006 0.0081
Schistosoma mansoni neuropeptide F-like receptor 0.0126 0.0072 0.0664
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Brugia malayi Calcitonin receptor-like protein seb-1 0.0297 0.0182 0.2378
Loa Loa (eye worm) hypothetical protein 0.0349 0.0216 0.2016
Echinococcus granulosus somatostatin receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma brucei transcription factor BTF3, putative 0.0022 0.0004 0.0038
Onchocerca volvulus Bile acid receptor homolog 0.0026 0.0007 0.029
Leishmania major hypothetical protein, conserved 0.5614 0.3635 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0041 0.0016 0.0201
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0029 0.0009 0.0099
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0174 0.0474
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0044 0.0018 0.0427
Echinococcus multilocularis peptidase Clp (S14 family) 0.0048 0.0021 0.002
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0283 0.0174 0.162
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0283 0.0174 0.0173
Echinococcus multilocularis serotonin receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Mycobacterium tuberculosis Conserved protein 0.0101 0.0055 0.1341
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0025 0.0006 0.0063
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0099 0.0054 0.0498
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0113 0.0063 0.0062
Echinococcus granulosus jumonji domain containing protein 0.0066 0.0033 0.0032
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0348 0.0216 0.0616
Brugia malayi M-phase phosphoprotein, mpp8 0.0124 0.007 0.0905
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0126 0.0072 0.0664
Loa Loa (eye worm) cytochrome P450 family protein 0.0071 0.0036 0.0329
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0176 0.0104 0.0103
Brugia malayi PHD-finger family protein 0.0048 0.002 0.0254
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0297 0.0182 0.17
Entamoeba histolytica hypothetical protein 0.0025 0.0006 0.0051
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0021 0.0281
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0041 0.0016 0.0149
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0047 0.002 0.0484
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0026 0.0007 0.0006
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0047 0.002 0.1101
Brugia malayi kap beta 3 protein 0.0029 0.0009 0.01
Brugia malayi hypothetical protein 0.0124 0.007 0.0905
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0024 0.0327
Loa Loa (eye worm) thioredoxin reductase 0.0136 0.0078 0.0724
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0094 0.0051 0.005
Schistosoma mansoni cytochrome P450 0.0044 0.0018 0.0162
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0067 0.0872
Brugia malayi F/Y-rich N-terminus family protein 0.0052 0.0023 0.0292
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0073 0.0037 0.0036
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0383 0.0238 0.3161
Echinococcus granulosus g protein coupled receptor 0.0126 0.0072 0.0071
Toxoplasma gondii endonuclease IV APN 0.0084 0.0044 0.0597
Loa Loa (eye worm) phosphatidylinositol 3 0.0232 0.014 0.1305
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0006 0.005
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0465 0.0292 0.3877
Schistosoma mansoni neuropeptide F-like receptor 0.0126 0.0072 0.0664
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0044 0.0018 0.0971
Schistosoma mansoni hypothetical protein 0.1663 0.1069 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.0026 0.0072
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0113 0.0063 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Entamoeba histolytica hypothetical protein 0.0025 0.0006 0.0051
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0126 0.0072 0.0071
Brugia malayi Dopamine receptor protein 1 0.0126 0.0072 0.0925
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0024 0.0066
Onchocerca volvulus 0.0126 0.0072 0.4394
Loa Loa (eye worm) hypothetical protein 0.0034 0.0011 0.0103
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0047 0.002 0.1139
Trichomonas vaginalis hypothetical protein 0.0025 0.0006 0.0051
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0108 0.0107
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0126 0.0072 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0146 0.1927
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus multilocularis neuropeptides capa receptor 0.0126 0.0072 0.0071
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0126 0.0072 0.0664
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Mycobacterium tuberculosis Probable hydrolase 0.0101 0.0055 0.1341
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0126 0.0072 0.0071
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0175 0.0103 0.1339
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0345 0.0213 1
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0091 0.0049 0.2799
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0052
Echinococcus multilocularis dro:myosuppressin receptor 0.0126 0.0072 0.0071
Trypanosoma cruzi cytochrome P450, putative 0.0071 0.0036 0.0098
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0232 0.014 0.1306
Schistosoma mansoni alpha glucosidase 0.0051 0.0023 0.021
Echinococcus multilocularis FTZ F1 alpha 0.0026 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0004 0.004
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0061 0.0029 0.0028
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.053 0.0334 0.444
Onchocerca volvulus 0.0126 0.0072 0.4394
Echinococcus granulosus lamin dm0 0.0135 0.0077 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Brugia malayi 6-phosphofructokinase 0.0119 0.0067 0.0868
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0009 0.0098
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0232 0.014 0.1308
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.0067 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Echinococcus multilocularis g protein coupled receptor 0.0126 0.0072 0.0071
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.205
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Plasmodium vivax thioredoxin reductase, putative 0.0136 0.0078 0.448
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Brugia malayi Cytochrome P450 family protein 0.0071 0.0036 0.0453
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.1854
Leishmania major cathepsin L-like protease 0.0049 0.0022 0.0056
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0158 0.0092 0.0091
Loa Loa (eye worm) glutaminase 2 0.0293 0.018 0.1676
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0044 0.0018 0.0427
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0048 0.0021 0.0499
Loa Loa (eye worm) G-protein coupled receptor 0.0126 0.0072 0.0665
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0126 0.0072 0.0664
Entamoeba histolytica hypothetical protein 0.0068 0.0034 0.0424
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0283 0.0174 0.2297
Echinococcus granulosus bloom syndrome protein 0.0024 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0126 0.0072 0.0071
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.066 0.0418 0.5571
Trypanosoma cruzi transcription factor btf3, putative 0.0022 0.0004 0.0008
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0011 0.0583
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0004 0.0003
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.0067 0.0066
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0038 0.0354
Brugia malayi Cytochrome P450 family protein 0.0121 0.0068 0.0878
Brugia malayi beta-NAC-like protein 0.0022 0.0004 0.004
Onchocerca volvulus 0.0101 0.0055 0.3358
Brugia malayi hypothetical protein 0.0019 0.0002 0.0013
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0044 0.0018 0.0971
Plasmodium falciparum glutathione reductase 0.0047 0.002 0.1139
Onchocerca volvulus 0.0022 0.0004 0.0103
Echinococcus granulosus importin subunit beta 1 0.0156 0.0091 0.009
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0055 0.0026 0.149
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0232 0.014 0.1824
Mycobacterium ulcerans lipase LipD 0.0101 0.0055 0.3052
Onchocerca volvulus 0.0064 0.0031 0.1823
Schistosoma mansoni smad1 5 8 and 0.0018 0.0001 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0026 0.0241
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0629 0.0398 0.5304
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0009 0.0118
Loa Loa (eye worm) hypothetical protein 0.0124 0.007 0.0651
Echinococcus granulosus microtubule associated protein 2 0.0596 0.0377 0.0376
Schistosoma mansoni loxhd1 0.0022 0.0004 0.0029
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0232 0.014 0.1304
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0004 0.0098
Schistosoma mansoni lamin 0.0135 0.0077 0.0715
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.119 0.0763 0.2185
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0067 0.0872
Schistosoma mansoni retinoic acid receptor RXR 0.0026 0.0007 0.0057
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0016 0.0015
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0126 0.0072 0.0931
Trichomonas vaginalis PIKK family atypical protein kinase 0.117 0.0749 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Plasmodium vivax importin-beta 2, putative 0.0156 0.0091 0.5222
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0026 0.0007 0.0073
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Echinococcus granulosus g-protein coupled receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0126 0.0072 0.0071
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0032 0.0298
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.0024 0.0023
Trypanosoma cruzi cytochrome P450, putative 0.0071 0.0036 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0024 0.1389
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0011 0.2304
Trichomonas vaginalis hypothetical protein 0.0029 0.0009 0.009
Schistosoma mansoni bromodomain containing protein 0.0075 0.0038 0.0351
Onchocerca volvulus 0.0126 0.0072 0.4394
Onchocerca volvulus 0.0126 0.0072 0.4394
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0044 0.0018 0.0971
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0345 0.0213 0.5221
Echinococcus granulosus sex peptide receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0126 0.0072 0.0071
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0047 0.0608
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0045 0.0019 0.005
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni topbp1 0.0019 0.0002 0.0014
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0091 0.0049 0.066
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0 0.0019
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni hypothetical protein 0.0021 0.0003 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Toxoplasma gondii PHD-finger domain-containing protein 0.0048 0.002 0.0276
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0047 0.002 0.0019
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0664 0.0421 0.561
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Entamoeba histolytica Ran family GTPase 0.0091 0.0049 0.0628
Brugia malayi Valyl-tRNA synthetase 0.0025 0.0006 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0108 0.0107
Plasmodium falciparum heterochromatin protein 1 0.0025 0.0006 0.0313
Mycobacterium leprae conserved hypothetical protein 0.0101 0.0055 0.2512
Schistosoma mansoni opsin-like receptor 0.0126 0.0072 0.0664
Loa Loa (eye worm) hypothetical protein 0.0132 0.0075 0.0701
Schistosoma mansoni biogenic amine receptor 0.0126 0.0072 0.0664
Trichomonas vaginalis PIKK family atypical protein kinase 0.117 0.0749 1
Mycobacterium tuberculosis Probable esterase LipL 0.0101 0.0055 0.1341
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0024 0.0005 0.0004
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0009 0.0118
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0629 0.0398 0.114
Loa Loa (eye worm) phosphatidylinositol 3 0.0739 0.047 0.439
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0019 0.0002 0.0089
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0028 0.0344
Onchocerca volvulus 0.0263 0.016 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.117 0.0749 0.2147
Brugia malayi larval opioid receptor 0.0126 0.0072 0.0925
Echinococcus multilocularis neuropeptide receptor A26 0.0423 0.0264 0.0263
Echinococcus granulosus 7TM GPCR rhodopsin 0.0126 0.0072 0.0071
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.117 0.0749 1
Echinococcus multilocularis geminin 0.035 0.0217 0.0216
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0099 0.0054 0.0053
Echinococcus multilocularis microtubule associated protein 2 0.0596 0.0377 0.0376
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0044 0.0018 0.0164
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.0067 0.3081
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0223 0.0135 0.1256
Schistosoma mansoni hypothetical protein 0.0203 0.0121 0.1129
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Echinococcus granulosus chromobox protein 1 0.0089 0.0047 0.0047
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Schistosoma mansoni biogenic amine (5HT) receptor 0.0126 0.0072 0.0664
Onchocerca volvulus 0.0019 0.0002 0.0001
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0044 0.0018 0.0971
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0629 0.0398 0.114
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0804 0.0512 0.0511
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Brugia malayi follicle stimulating hormone receptor 0.0561 0.0354 0.4633
Loa Loa (eye worm) hypothetical protein 0.0084 0.0044 0.041
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0007 0.0057
Brugia malayi jmjC domain containing protein 0.0066 0.0032 0.0409
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0035 0.0012 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0004 0.0028
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0068 0.0034 0.0033
Toxoplasma gondii histone lysine methyltransferase SET1 0.0214 0.0128 0.1731
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0011 0.0601
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0091 0.0049 0.0048
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0006 0.0079
Brugia malayi hypothetical protein 0.0134 0.0076 0.099
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0126 0.0072 0.0664
Giardia lamblia Phosphatidylinositol 4-kinase 0.0232 0.014 0.1846
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0071 0.0036 0.0035
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.0026 0.0069
Echinococcus granulosus dnaJ subfamily B 0.0316 0.0195 0.0194
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0051 0.0023 0.0281
Echinococcus granulosus serotonin receptor 0.0126 0.0072 0.0071
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0804 0.0512 0.4783
Onchocerca volvulus 0.0124 0.007 0.4298
Plasmodium vivax hypothetical protein 0.0232 0.014 0.8057
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0094 0.0051 0.005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0024 0.0217
Plasmodium vivax hypothetical protein, conserved 0.0048 0.002 0.1172
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0044 0.0018 0.0047
Echinococcus granulosus tumor protein p63 0.0434 0.0272 0.0271
Brugia malayi Glycosyl hydrolases family 31 protein 0.0232 0.014 0.1826
Echinococcus multilocularis chromobox protein 2 0.0025 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.8057
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0009 0.0008
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0013 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Echinococcus multilocularis musashi 0.0135 0.0077 0.0076
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0091 0.0049 0.0628
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.003
Schistosoma mansoni fkbp-rapamycin associated protein 0.0649 0.0411 0.3842
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0004 0.004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0007 0.0073
Loa Loa (eye worm) glutaminase 0.0293 0.018 0.1676
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Brugia malayi Bromodomain containing protein 0.0054 0.0025 0.0307
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0019 0.0169
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0063 0.0582
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0012 0.0168
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0059 0.0028 0.1624
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Trypanosoma brucei protein kinase, putative 0.0057 0.0026 0.0334
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0026 0.0007 0.0073
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.119 0.0763 0.0762
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0232 0.014 0.0139
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0001 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Onchocerca volvulus 0.0126 0.0072 0.4394
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.0026 0.0242
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0005 0.0004
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0063 0.0582
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) Smad1 0.0018 0.0001 0.0006
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0015 0.0184
Leishmania major hypothetical protein, unknown function 0.0232 0.014 0.0381
Echinococcus multilocularis importin subunit beta 1 0.0156 0.0091 0.009
Echinococcus multilocularis thioredoxin glutathione reductase 0.0136 0.0078 0.0077
Toxoplasma gondii ABC1 family protein 0.0101 0.0055 0.0744
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0006 0.0051
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0025 0.0006 0.0079
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0176 0.0104 0.0282
Onchocerca volvulus 0.0134 0.0077 0.4717
Echinococcus granulosus hypothetical protein 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0054 0.0024 0.0224
Loa Loa (eye worm) phosphatidylinositol 3 0.0232 0.014 0.1305
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0044 0.0018 0.0427
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Schistosoma mansoni kinase 0.009 0.0048 0.0442
Echinococcus granulosus neuropeptide Y receptor 0.0126 0.0072 0.0071
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.119 0.0763 1
Brugia malayi hypothetical protein 0.0068 0.0034 0.0429
Trichomonas vaginalis importin beta-1, putative 0.0126 0.0072 0.0931
Onchocerca volvulus 0.0126 0.0072 0.4394
Entamoeba histolytica protein kinase rad3, putative 0.0649 0.0411 0.5477
Trypanosoma brucei importin beta-1 subunit, putative 0.0156 0.0091 0.1196
Schistosoma mansoni opsin-like receptor 0.0126 0.0072 0.0664
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0047 0.002 0.0052
Loa Loa (eye worm) hypothetical protein 0.0048 0.002 0.0187
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Echinococcus granulosus Chromobox protein 3 0.0025 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0053 0.0024 0.0222
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0176 0.0104 0.0103
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0126 0.0072 0.0925
Trichomonas vaginalis sucrase-isomaltase, putative 0.0051 0.0023 0.0281
Echinococcus granulosus tachykinin peptides receptor 99D 0.0126 0.0072 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.005 0.0022 0.0274
Echinococcus granulosus FTZ F1 alpha 0.0026 0.0007 0.0006
Mycobacterium ulcerans endonuclease IV 0.0084 0.0044 0.2447
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0176 0.0104 0.0965
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) cytochrome P450 0.0044 0.0018 0.0163
Leishmania major cytochrome p450-like protein 0.0071 0.0036 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0026 0.0007 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.1151 0.0737 0.9838
Loa Loa (eye worm) hypothetical protein 0.0433 0.027 0.2526
Toxoplasma gondii melibiase subfamily protein 0.0113 0.0063 0.0846
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0026 0.0325
Schistosoma mansoni lipoxygenase 0.0061 0.0029 0.0266
Schistosoma mansoni chromobox protein 0.0025 0.0006 0.005
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0005 0.0004
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1139 0.0729 0.9737
Loa Loa (eye worm) acetyltransferase 0.0158 0.0092 0.0856
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0113 0.0063 0.0062
Brugia malayi G protein-coupled receptor 0.0126 0.0072 0.0925
Brugia malayi hypothetical protein 0.0022 0.0004 0.0034
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0126 0.0072 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0047 0.002 0.0054
Loa Loa (eye worm) phosphatidylinositol 3 0.0232 0.014 0.1305
Onchocerca volvulus 0.0026 0.0007 0.029
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0001 0.0005
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0067 0.0872
Loa Loa (eye worm) hypothetical protein 0.0178 0.0105 0.0981
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0011 0.0142
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.031 0.0191 0.467
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0044 0.0018 0.0427
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0015 0.0137
Brugia malayi N-terminal motif family protein 0.0185 0.011 0.1428
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.0398
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0091 0.0049 0.0137
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0047 0.002 0.0184
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Leishmania major phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.0381
Echinococcus multilocularis neuropeptide receptor 0.0126 0.0072 0.0071
Echinococcus granulosus fmrfamide receptor 0.0126 0.0072 0.0071
Echinococcus granulosus GPCR family 2 0.0094 0.0051 0.005
Schistosoma mansoni chromobox protein 0.0025 0.0006 0.005
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0019 0.0002 0.0002
Schistosoma mansoni neuropeptide f receptor 76f 0.0126 0.0072 0.0664
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.0023 0.0062
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0044 0.0018 0.0971
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0091 0.0049 0.0637
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0345 0.0213 0.5221
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.0026 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0418 0.0261 0.3464
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0283 0.0174 0.0173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0668 0.0423 0.5638
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0094 0.0051 0.005
Echinococcus granulosus chromobox protein 2 0.0025 0.0006 0.0005
Schistosoma mansoni neuropeptide receptor 0.0126 0.0072 0.0664
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0026 0.0007 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0044 0.2546
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.002 0.0054
Entamoeba histolytica hypothetical protein 0.0232 0.014 0.1846
Treponema pallidum NADH oxidase 0.0047 0.002 0.2786
Brugia malayi Glycosyl hydrolases family 31 protein 0.0019 0.0002 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0044 0.0018 0.0427
Loa Loa (eye worm) CHromoDomain protein family member 0.0033 0.0011 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0232 0.014 0.1846
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0007 0.0057
Entamoeba histolytica hypothetical protein 0.0022 0.0004 0.0028
Onchocerca volvulus 0.0022 0.0004 0.0103
Brugia malayi Glycosyl hydrolases family 31 protein 0.0051 0.0023 0.0288
Plasmodium falciparum thioredoxin reductase 0.0136 0.0078 0.447
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0073 0.0037 0.0502
Trypanosoma cruzi hypothetical protein, conserved 0.5383 0.3485 1
Echinococcus multilocularis neuropeptide receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.0026 0.0025
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0026 0.0007 0.0006
Echinococcus multilocularis lamin dm0 0.0135 0.0077 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0002 0.0002
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.116 0.0743 0.2041
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.117 0.0749 0.0748
Onchocerca volvulus 0.0126 0.0072 0.4394
Brugia malayi isocitrate dehydrogenase 0.0018 0.0001 0.0003
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0048 0.002 0.0187
Schistosoma mansoni hypothetical protein 0.035 0.0217 0.2024
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.115 0.0737 0.9832
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0026 0.0007 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Mycobacterium tuberculosis Conserved protein 0.0101 0.0055 0.1341
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Toxoplasma gondii ATPase, AAA family protein 0.0019 0.0002 0.0028
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0232 0.014 0.8054
Echinococcus multilocularis somatostatin receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0039 0.0015 0.0136
Loa Loa (eye worm) phosphatidylinositol 3 0.115 0.0737 0.6886
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0448 0.028 0.0279
Echinococcus multilocularis neuropeptide FF receptor 2 0.0126 0.0072 0.0071
Schistosoma mansoni neuropeptide receptor 0.0126 0.0072 0.0664
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0283 0.0174 0.162
Entamoeba histolytica transcription factor BTF3, putative 0.0022 0.0004 0.0028
Echinococcus granulosus geminin 0.035 0.0217 0.0216
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0004 0.0205
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0047 0.002 0.0252
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.117 0.0749 0.2058
Chlamydia trachomatis DNA ligase 0.0019 0.0002 0.0363
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0664 0.0421 0.1204
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.0024 0.0023
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0283 0.0174 0.2297
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0398 0.0248 0.3292
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0015 0.0359
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0063 0.0582
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0044 0.0018 0.0971
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0232 0.014 0.1824
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0011 0.0142
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0033
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0032 0.0297
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0017 0.0197
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0026 0.0007 0.0073
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.117 0.0749 0.0748
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0005 0.0042
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0232 0.014 0.1854
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0047 0.002 0.0054
Schistosoma mansoni ran 0.0091 0.0049 0.0453
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0022 0.0058
Echinococcus multilocularis serine protein kinase ATM 0.0664 0.0421 0.042
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0025 0.0006 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0044 0.0018 0.0427
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0004 0.0098
Mycobacterium tuberculosis Probable lipase LipE 0.0101 0.0055 0.1341
Schistosoma mansoni hypothetical protein 0.0126 0.0072 0.0664
Loa Loa (eye worm) neuropeptide F receptor 0.0126 0.0072 0.0665
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0048 0.0021 0.0499
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0011 0.1307
Onchocerca volvulus 0.0126 0.0072 0.4394
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.005 0.0022 0.0267
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0021 0.002
Loa Loa (eye worm) phosphatidylinositol 3 0.0232 0.014 0.1305
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0283 0.0174 0.2297
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0232 0.014 0.1846
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0019 0.0002 0.0002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0026 0.0007 0.0006
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0024 0.0005 0.0004
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0044 0.0018 0.0047
Loa Loa (eye worm) transcription factor SMAD2 0.026 0.0158 0.1477
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0044 0.0018 0.0427
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0044 0.0018 0.0971
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0126 0.0072 0.0925
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0101 0.0055 0.1341
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.8057
Brugia malayi G protein-coupled receptor F59B2.13 0.0126 0.0072 0.0925
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.2121
Loa Loa (eye worm) phosphatidylinositol 3 0.117 0.0749 0.7004
Echinococcus multilocularis beta LACTamase domain containing family member 0.0101 0.0055 0.0054
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0007 0.0057
Echinococcus multilocularis Zinc finger, PHD finger 0.0283 0.0174 0.0173
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0232 0.014 0.0139
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0026 0.0325
Schistosoma mansoni histamine h1 receptor 0.0126 0.0072 0.0664
Schistosoma mansoni hypothetical protein 0.035 0.0217 0.2024
Echinococcus granulosus tm gpcr rhodopsin 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0034
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0015 0.0014
Onchocerca volvulus 0.0135 0.0077 0.4738
Schistosoma mansoni neuropeptide receptor 0.0126 0.0072 0.0664
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Schistosoma mansoni hypothetical protein 0.0316 0.0195 0.1815
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Brugia malayi cytochrome P450 0.0044 0.0018 0.022
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0035 0.0012 0.0011
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0044 0.0018 0.0427
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0006 0.0051
Schistosoma mansoni hypothetical protein 0.0126 0.0072 0.0664
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Entamoeba histolytica acyl-CoA synthetase, putative 0.0022 0.0004 0.0028
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0561 0.0354 0.3306
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0001 0.005
Echinococcus granulosus PHD finger protein rhinoceros 0.0048 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0065 0.0032 0.0293
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.8378
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0044 0.0018 0.0427
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0126 0.0072 0.0071
Echinococcus multilocularis g protein coupled receptor 0.0126 0.0072 0.0071
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0158 0.0092 0.0855
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0044 0.0018 0.0221
Plasmodium vivax sentrin-specific protease 1, putative 0.005 0.0022 0.126
Loa Loa (eye worm) steroid hormone receptor 0.0026 0.0007 0.0058
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0022 0.0004 0.0205
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Mycobacterium ulcerans esterase/lipase LipP 0.0101 0.0055 0.3052
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0044 0.0018 0.0427
Entamoeba histolytica acyl-CoA synthetase, putative 0.0022 0.0004 0.0028
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.0067 0.3723
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.117 0.0749 0.7003
Brugia malayi steroid hormone receptor 0.0026 0.0007 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.068 0.0431 0.574
Toxoplasma gondii exonuclease III APE 0.0039 0.0015 0.0204
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0047 0.002 0.0272
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0232 0.014 0.0398
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0001 0.0021
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0044 0.0018 0.0971
Toxoplasma gondii HEAT repeat-containing protein 0.0156 0.0091 0.1224
Trichomonas vaginalis esterase, putative 0.0101 0.0055 0.0711
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0126 0.0072 0.0925
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0126 0.0072 0.0071
Brugia malayi nuclear hormone receptor 0.0026 0.0007 0.0073
Mycobacterium ulcerans hypothetical protein 0.0101 0.0055 0.3052
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0044 0.0018 0.0427
Brugia malayi CXXC zinc finger family protein 0.0109 0.006 0.0778
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0156 0.0091 0.009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0024 0.0217
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Onchocerca volvulus 0.0126 0.0072 0.4394
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Onchocerca volvulus 0.0126 0.0072 0.4394
Plasmodium vivax replication factor C subunit 1, putative 0.0019 0.0002 0.0111
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0094 0.0051 0.0649
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0126 0.0072 0.0665
Plasmodium vivax transportin, putative 0.0029 0.0009 0.0496
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0026 0.0007 0.0006
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0126 0.0072 0.0664
Echinococcus granulosus peptide allatostatin:somatostatin 0.0126 0.0072 0.0071
Plasmodium vivax glutathione reductase, putative 0.0136 0.0078 0.448
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0046 0.0591
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0126 0.0072 0.0071
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0022 0.0058
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0068 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni RAR-like nuclear receptor 0.0026 0.0007 0.0057
Brugia malayi Tachykinin-like peptides receptor 99D 0.0126 0.0072 0.0925
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Onchocerca volvulus Serine\/threonine kinase homolog 0.0176 0.0104 0.6424
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0044 0.0018 0.0971
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0032 0.0297
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0649 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0203 0.0121 0.113
Leishmania major phosphatidylinositol kinase related protein, putative 0.0246 0.015 0.0408
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0047 0.002 0.1139
Loa Loa (eye worm) hypothetical protein 0.0053 0.0024 0.0218
Echinococcus granulosus neuropeptides capa receptor 0.0126 0.0072 0.0071
Onchocerca volvulus 0.0124 0.007 0.4298
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0091 0.0049 0.0453
Toxoplasma gondii NADPH-glutathione reductase 0.0047 0.002 0.0272
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0232 0.014 0.1304
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0067 0.0872
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0013 0.0151
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0047 0.002 0.0252
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0044 0.0018 0.0971
Loa Loa (eye worm) helicase 0.0025 0.0006 0.0051
Loa Loa (eye worm) phosphofructokinase 0.0119 0.0067 0.0624
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0649 0.0411 0.5386
Echinococcus granulosus ecdysone induced protein 78C 0.0026 0.0007 0.0006
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0075 0.0038 0.0486
Brugia malayi G-protein coupled receptor 0.0126 0.0072 0.0925
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0026 0.0007 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Mycobacterium leprae conserved hypothetical protein 0.0232 0.014 0.6524
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0091 0.0049 0.2812
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0015 0.0171
Leishmania major hypothetical protein, conserved 0.0101 0.0055 0.0148
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0026 0.0007 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.067 0.0425 0.5659
Trichomonas vaginalis PIKK family atypical protein kinase 0.0232 0.014 0.1846
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0028 0.0344
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0007 0.0006
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.025 0.0152 0.2015
Trichomonas vaginalis helicase, putative 0.0025 0.0006 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0009 0.0075
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0645 0.0408 1
Echinococcus multilocularis jumonji domain containing protein 0.0066 0.0033 0.0032
Trichomonas vaginalis D-aminoacylase, putative 0.0101 0.0055 0.0711
Echinococcus granulosus transportin 1 0.0029 0.0009 0.0008
Brugia malayi G-protein coupled receptor 0.0126 0.0072 0.0925
Schistosoma mansoni transcription factor LCR-F1 0.0068 0.0034 0.0311
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0108 0.1401
Echinococcus granulosus peregrin 0.0054 0.0025 0.0024
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.0067 0.0181
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.0023 0.0062
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0015 0.0038
Schistosoma mansoni microtubule-associated protein tau 0.0596 0.0377 0.3518
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0011 0.0114
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0067 0.0624
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0015 0.0175
Echinococcus granulosus g protein coupled receptor 0.0126 0.0072 0.0071
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0448 0.028 0.3667
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0283 0.0174 0.162
Echinococcus multilocularis neutral alpha glucosidase AB 0.0051 0.0023 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0006 0.0331
Loa Loa (eye worm) kap beta 3 protein 0.0029 0.0009 0.0077
Brugia malayi putative neuropeptide receptor 0.0126 0.0072 0.0925
Trypanosoma cruzi trypanothione reductase, putative 0.0136 0.0078 0.022
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0025 0.0006 0.0005
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.117 0.0749 1
Onchocerca volvulus 0.0126 0.0072 0.4394
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0126 0.0072 0.0664
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.205
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1663 0.1069 1
Echinococcus multilocularis 0.0044 0.0018 0.0017
Giardia lamblia Kinase, PLK 0.0176 0.0104 0.136
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0296 0.0182 0.2409
Schistosoma mansoni cellular tumor antigen P53 0.0064 0.0031 0.0284
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0156 0.0091 0.009
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.049 0.0308 0.0307
Echinococcus multilocularis nibrin 0.0019 0.0002 0.0001
Brugia malayi latrophilin 2 splice variant baaae 0.0203 0.0121 0.1578
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0004 0.0003
Brugia malayi glutaminase DH11.1 0.0293 0.018 0.2345
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0048 0.0021 0.0887
Schistosoma mansoni adenoreceptor 0.0126 0.0072 0.0664
Brugia malayi hypothetical protein 0.0053 0.0024 0.0304
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0136 0.0078 0.1898
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0015 0.004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Schistosoma mansoni growth hormone secretagogue receptor 0.0126 0.0072 0.0664
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0067 0.0872
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0004 0.0008
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0044 0.0018 0.0971
Loa Loa (eye worm) cytochrome P450 family protein 0.0071 0.0036 0.0329
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0047 0.002 0.1101
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis dnaJ subfamily B 0.0316 0.0195 0.0194
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0044 0.0018 0.0427
Entamoeba histolytica acyl-coA synthetase, putative 0.0022 0.0004 0.0028
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.001 0.0009
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0101 0.0055 0.0511
Brugia malayi serine/threonine-protein kinase plk-2 0.0176 0.0104 0.1347
Trypanosoma cruzi polo-like protein kinase, putative 0.0176 0.0104 0.0294
Mycobacterium tuberculosis Probable dehydrogenase 0.031 0.0191 0.467
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.119 0.0763 0.7129
Echinococcus granulosus neuropeptide Y receptor 0.0126 0.0072 0.0071
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0015 0.0817
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0051 0.0023 0.0211
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0002 0.0002
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0101 0.0055 0.1341
Brugia malayi acetyltransferase, GNAT family protein 0.0158 0.0092 0.1193
Brugia malayi Dopamine receptor 0.0126 0.0072 0.0925
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Schistosoma mansoni importin-beta 2 0.0029 0.0009 0.0077
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0022 0.0004 0.0205
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0005 0.0004
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0044 0.0018 0.0427
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0026 0.0007 0.0073
Leishmania major cytochrome p450-like protein 0.0044 0.0018 0.0046
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.031 0.0191 0.8937
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Plasmodium vivax SET domain protein, putative 0.0035 0.0012 0.071
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0084 0.0044 0.1075
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0011 0.0583
Brugia malayi PHD-finger family protein 0.0035 0.0013 0.0151
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Loa Loa (eye worm) TAR-binding protein 0.0223 0.0135 0.1256
Echinococcus multilocularis neuropeptide Y receptor 0.0126 0.0072 0.0071
Brugia malayi Pre-SET motif family protein 0.0231 0.014 0.182
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0348 0.0216 0.2014
Echinococcus multilocularis zinc finger protein 0.003 0.0009 0.0008
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0047 0.002 0.1156
Trichomonas vaginalis PIKK family atypical protein kinase 0.1139 0.0729 0.9737
Schistosoma mansoni biogenic amine receptor 0.0126 0.0072 0.0664
Schistosoma mansoni DNA ligase IV 0.0019 0.0002 0.0014
Trichomonas vaginalis penicillin-binding protein, putative 0.0101 0.0055 0.0711
Trichomonas vaginalis PIKK family atypical protein kinase 0.0668 0.0423 0.5638
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0024 0.0306
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0065 0.0032 0.0031
Mycobacterium leprae putative cytochrome p450 0.0044 0.0018 0.0748
Brugia malayi Doublecortin family protein 0.0022 0.0004 0.0034
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Loa Loa (eye worm) hypothetical protein 0.0649 0.0411 0.3842
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0029 0.0264
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0007 0.0006
Echinococcus multilocularis transcription factor btf3 0.0022 0.0004 0.0003
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0038 0.0354
Brugia malayi ORL1-like opioid receptor 0.0126 0.0072 0.0925
Echinococcus multilocularis PHD finger protein rhinoceros 0.0048 0.002 0.002
Loa Loa (eye worm) heterochromatin protein 1 0.0089 0.0047 0.044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Giardia lamblia PHD finger protein 15 0.0048 0.002 0.0247
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0629 0.0398 0.5304
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0246 0.015 0.0426
Schistosoma mansoni opsin-like receptor 0.0126 0.0072 0.0664
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0026 0.0007 0.0057
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0001 0.0004
Echinococcus granulosus tar DNA binding protein 0.0223 0.0135 0.0134
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0071 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus multilocularis G protein coupled receptor 139 0.0126 0.0072 0.0071
Schistosoma mansoni rab6-interacting 0.0022 0.0004 0.0029
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0026 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0004 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Echinococcus granulosus peptidase Clp S14 family 0.0048 0.0021 0.002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.5047 0.3267 0.3267
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.0026 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Loa Loa (eye worm) RNA binding protein 0.0223 0.0135 0.1256
Echinococcus multilocularis peregrin 0.0054 0.0025 0.0024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Loa Loa (eye worm) hypothetical protein 0.0082 0.0043 0.0394
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0044 0.0018 0.0047
Brugia malayi RNA, U transporter 1 0.0443 0.0277 0.3627
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0044 0.0018 0.0971
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.0026 0.0025
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.0026 0.0334
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.117 0.0749 0.9824
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0026 0.0007 0.0058
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.053 0.0334 0.444
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0004 0.003
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0011 0.0114
Mycobacterium leprae Conserved hypothetical protein 0.0044 0.0018 0.0748
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0025 0.0006 0.0187
Leishmania major glycosyl hydrolase-like protein 0.0019 0.0002 0.0002
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0006 0.005
Loa Loa (eye worm) hypothetical protein 0.0232 0.014 0.1305
Echinococcus granulosus g protein coupled receptor 0.0126 0.0072 0.0071
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0015 0.0863
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0065 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0348 0.0216 0.2868
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0126 0.0072 0.0925
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0283 0.0174 0.2297
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0033 0.0011 0.001
Schistosoma mansoni smad1 5 8 and 0.0018 0.0001 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0004 0.0223
Echinococcus granulosus lysosomal alpha glucosidase 0.0232 0.014 0.0139
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.0216 0.2861
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0004 0.0197
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0047 0.002 0.0252
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0044 0.0018 0.0971
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.0067 0.1635
Loa Loa (eye worm) latrophilin receptor protein 2 0.0094 0.0051 0.0468
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0232 0.014 0.1304
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0004 0.0003
Plasmodium falciparum sentrin-specific protease 1 0.005 0.0022 0.1243
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0001 0.0008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0007 0.0006
Brugia malayi neuropeptide F receptor 0.0126 0.0072 0.0925
Brugia malayi TAR-binding protein 0.0223 0.0135 0.1755
Plasmodium falciparum phd finger protein, putative 0.0048 0.002 0.1156
Trypanosoma brucei glucosidase, putative 0.0051 0.0023 0.029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0108 0.0107
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0099 0.0054 0.0498
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0126 0.0072 0.0664
Loa Loa (eye worm) MH2 domain-containing protein 0.026 0.0158 0.1477
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 1.5416 1 1
Loa Loa (eye worm) hypothetical protein 0.0182 0.0108 0.1002
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0117 0.0065 0.0184
Schistosoma mansoni Smad4 0.0018 0.0001 0.0005
Brugia malayi 6-phosphofructokinase 0.0119 0.0067 0.0868
Echinococcus granulosus mixed lineage leukemia protein mll 0.0028 0.0008 0.0007
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0051 0.0023 0.0281
Onchocerca volvulus Protein ultraspiracle homolog 0.0026 0.0007 0.029
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0004 0.0204
Echinococcus granulosus tm gpcr rhodopsin 0.0126 0.0072 0.0071
Echinococcus multilocularis RUN 0.0022 0.0004 0.0003
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.119 0.0763 0.0762
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0033 0.0011 0.01
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0072 0.0036 0.0336
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0126 0.0072 0.0664
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0071 0.0036 0.1962
Trypanosoma cruzi transcription factor btf3, putative 0.0022 0.0004 0.0008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0108 0.0107
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0004 0.0087
Echinococcus multilocularis lysosomal alpha glucosidase 0.0232 0.014 0.0139
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0027 0.0026
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0015 0.0175
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0001 0.0069
Trypanosoma brucei cytochrome P450, putative 0.0071 0.0036 0.0459
Brugia malayi Cytochrome P450 family protein 0.0044 0.0018 0.022
Schistosoma mansoni ap endonuclease 0.0039 0.0015 0.0136
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0025 0.0006 0.0606
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0004 0.0003
Mycobacterium ulcerans glutaminase 0.0293 0.018 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.117 0.0749 0.2147
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0007 0.0073
Loa Loa (eye worm) TYRA-2 protein 0.0126 0.0072 0.0665
Echinococcus multilocularis allatostatin A receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0051 0.0023 0.0281
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0565 0.0356 0.4741
Onchocerca volvulus 0.0135 0.0077 0.4738
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.0026 0.0069
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0044 0.0018 0.0046
Echinococcus granulosus neuropeptide receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0004 0.0031
Echinococcus multilocularis orexin receptor type 2 0.0126 0.0072 0.0071
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0044 0.0018 0.0427
Brugia malayi glutathione reductase 0.0136 0.0078 0.1008
Entamoeba histolytica hypothetical protein 0.0068 0.0034 0.0424
Plasmodium falciparum replication factor C subunit 1, putative 0.0019 0.0002 0.0092
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0283 0.0174 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0126 0.0072 0.0664
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0297 0.0182 0.2378
Schistosoma mansoni cpg binding protein 0.0117 0.0066 0.0609
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0003 0.0163
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0015 0.2003
Toxoplasma gondii thioredoxin reductase 0.0136 0.0078 0.105
Brugia malayi intermediate filament protein 0.0135 0.0077 0.0997
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0011 0.2304
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0044 0.0018 0.0427
Trypanosoma cruzi hypothetical protein, conserved 0.0101 0.0055 0.0155
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0084 0.0044 0.0567
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0004 0.004
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0101 0.0055 0.071
Leishmania major cytochrome p450-like protein 0.0044 0.0018 0.0046
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0026 0.0007 0.029
Brugia malayi chromobox protein homolog 3 0.0055 0.0026 0.0322
Echinococcus multilocularis Chromo domain 0.0025 0.0006 0.0005
Plasmodium falciparum thioredoxin reductase 0.0047 0.002 0.1139
Echinococcus multilocularis GPCR, family 2 0.0094 0.0051 0.005
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0044 0.0018 0.0427
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0026 0.0007 0.0057
Loa Loa (eye worm) hypothetical protein 0.0185 0.011 0.1024
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0283 0.0174 0.2342
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Brugia malayi Steroid receptor seven-up type 2 0.0026 0.0007 0.0073
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0004 0.0008
Schistosoma mansoni hypothetical protein 0.0048 0.002 0.0187
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0021 0.1191
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0026 0.0007 0.0058
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0044 0.0018 0.0971
Entamoeba histolytica hypothetical protein 0.0232 0.014 0.1846
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0232 0.014 0.1887
Schistosoma mansoni alpha-glucosidase 0.0199 0.0119 0.111
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0025 0.0006 0.0313
Brugia malayi CHD4 protein 0.0033 0.0011 0.0132
Plasmodium falciparum importin beta, putative 0.0156 0.0091 0.5213
Brugia malayi Protein cec-1. 0.0025 0.0006 0.0063
Echinococcus multilocularis sex peptide receptor 0.0126 0.0072 0.0071
Schistosoma mansoni biogenic amine (5HT) receptor 0.0126 0.0072 0.0664
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0026 0.0316
Plasmodium vivax hypothetical protein, conserved 0.0232 0.014 0.8057
Brugia malayi Intermediate filament tail domain containing protein 0.0135 0.0077 0.0997
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.8378
Brugia malayi GnHR receptor homolog 0.0126 0.0072 0.0925
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0804 0.0512 0.0511
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0025 0.0006 0.0338
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0024 0.0066
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Entamoeba histolytica HEAT repeat domain containing protein 0.0029 0.0009 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0014 0.0166
Echinococcus granulosus beta LACTamase domain containing family member 0.0101 0.0055 0.0054
Entamoeba histolytica hypothetical protein 0.0025 0.0006 0.0051
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0044 0.0018 0.0971
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0022 0.0004 0.0205
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0031 0.0009 0.0108
Schistosoma mansoni hypothetical protein 0.0024 0.0005 0.0043
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Trypanosoma cruzi cruzipain precursor, putative 0.0049 0.0022 0.0058
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0174 0.0495
Leishmania major phosphatidylinositol kinase, putative 0.0232 0.014 0.0381
Schistosoma mansoni hypothetical protein 0.0068 0.0034 0.0311
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0004 0.0028
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0047 0.002 0.4501
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Brugia malayi Latrophilin receptor protein 2 0.0094 0.0051 0.0649
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0006 0.005
Brugia malayi hypothetical protein 0.0022 0.0004 0.0034
Echinococcus multilocularis fmrfamide receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis transportin 1 0.0029 0.0009 0.0008
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.0026 0.0325
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0044 0.0018 0.0971
Trichomonas vaginalis D-aminoacylase, putative 0.0101 0.0055 0.0711
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0067 0.0872
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0649 0.0411 0.041
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.117 0.0749 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0022 0.0004 0.0205
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Schistosoma mansoni chromobox protein 0.0089 0.0047 0.0439
Loa Loa (eye worm) hypothetical protein 0.0055 0.0026 0.0235
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0017 0.0942
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0003 0.0026
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0044 0.0018 0.0971
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0006 0.0079
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0348 0.0216 0.2819
Loa Loa (eye worm) intermediate filament protein 0.0135 0.0077 0.0716
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.005 0.0022 0.0297
Brugia malayi ecdysteroid receptor 0.0026 0.0007 0.0073
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Schistosoma mansoni topbp1 0.0019 0.0002 0.0014
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0126 0.0072 0.0665
Echinococcus granulosus allatostatin A receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0126 0.0072 0.0071
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0232 0.014 0.1887
Brugia malayi Thioredoxin reductase 0.0136 0.0078 0.1008
Brugia malayi beta-lactamase family protein 0.0101 0.0055 0.071
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0028 0.0008 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Mycobacterium tuberculosis Probable oxidoreductase 0.0345 0.0213 0.5221
Loa Loa (eye worm) CYP4Cod1 0.0071 0.0036 0.0329
Plasmodium vivax hypothetical protein, conserved 0.0101 0.0055 0.3171
Brugia malayi hypothetical protein 0.0019 0.0002 0.0013
Mycobacterium tuberculosis Probable reductase 0.031 0.0191 0.467
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0067 0.0624
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0002 0.001
Trypanosoma cruzi importin beta-1 subunit, putative 0.0126 0.0072 0.0202
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0731 0.0464 0.6191
Trichomonas vaginalis penicillin-binding protein, putative 0.0101 0.0055 0.0711
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Schistosoma mansoni lamin 0.0135 0.0077 0.0715
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0108 0.1003
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0044 0.0018 0.0427
Trichomonas vaginalis Heterochromatin protein, putative 0.0025 0.0006 0.0051
Echinococcus multilocularis Chromobox protein 3 0.0025 0.0006 0.0005
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0232 0.014 0.0398
Giardia lamblia Hypothetical protein 0.0232 0.014 0.1846
Echinococcus multilocularis translational activator gcn1 0.0029 0.0009 0.0008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0007 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0007 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0007 0.0073
Echinococcus granulosus sentrin specific protease 1 0.005 0.0022 0.0021
Echinococcus granulosus tm gpcr rhodopsin 0.5047 0.3267 0.3267
Echinococcus multilocularis fmrfamide receptor 0.0126 0.0072 0.0071
Echinococcus granulosus lamin 0.0135 0.0077 0.0076
Loa Loa (eye worm) hypothetical protein 0.0722 0.0458 0.4282
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis PIKK family atypical protein kinase 0.115 0.0737 0.9832
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0001 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0668 0.0423 0.5638
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0073 0.0037 0.1662
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0012 0.0112
Schistosoma mansoni glutaminase 0.0293 0.018 0.1676
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0051 0.0023 0.0281
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0001 0.0006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0108 0.1003
Onchocerca volvulus 0.0232 0.014 0.872
Echinococcus multilocularis cpg binding protein 0.0117 0.0066 0.0065
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0232 0.014 0.1887
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0063 0.0582
Loa Loa (eye worm) hypothetical protein 0.049 0.0308 0.2876
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0232 0.014 0.8054
Entamoeba histolytica serine/threonine protein kinase, putative 0.0176 0.0104 0.136
Leishmania major importin beta-1 subunit, putative 0.0126 0.0072 0.0193
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0126 0.0072 0.0931
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0047 0.002 0.1156
Brugia malayi Dopamine receptor protein 2 0.0126 0.0072 0.0925
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0006 0.0051
Trichomonas vaginalis maltase-glucoamylase, putative 0.0051 0.0023 0.0281
Entamoeba histolytica hypothetical protein 0.0126 0.0072 0.0931
Mycobacterium tuberculosis Probable lipase LipD 0.0101 0.0055 0.1341
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Loa Loa (eye worm) hypothetical protein 0.0297 0.0182 0.17
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Entamoeba histolytica hypothetical protein 0.0565 0.0356 0.4741
Loa Loa (eye worm) histone methyltransferase 0.0035 0.0012 0.011
Echinococcus multilocularis chromobox protein 1 0.0089 0.0047 0.0047
Schistosoma mansoni importin beta-1 0.0156 0.0091 0.0844
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0135 0.0077 0.0716
Brugia malayi DKFZp564C0469 protein 0.0019 0.0002 0.0013
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0004 0.009
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0232 0.014 0.1846
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0101 0.0055 0.1341
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0004 0.0038
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0664 0.0421 0.5512
Brugia malayi Pax transcription activation domain interacting protein 0.0019 0.0002 0.0013
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0629 0.0398 0.5217
Brugia malayi Importin beta-1 subunit 0.0156 0.0091 0.1177
Brugia malayi Melibiase family protein 0.0075 0.0038 0.0489
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.005 0.0022 0.0266
Brugia malayi MH2 domain containing protein 0.026 0.0158 0.2065
Loa Loa (eye worm) hypothetical protein 0.0178 0.0105 0.0981
Brugia malayi putative neuropeptide receptor NPR1 0.0126 0.0072 0.0925
Loa Loa (eye worm) cytochrome P450 family protein 0.0121 0.0068 0.0631
Giardia lamblia GTOR 0.117 0.0749 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis thyroid hormone receptor alpha 0.0026 0.0007 0.0006
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0015 0.004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0007 0.0073
Loa Loa (eye worm) hypothetical protein 0.0062 0.003 0.0278
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0047 0.002 0.5162
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0004 0.0186
Loa Loa (eye worm) hypothetical protein 0.0064 0.0031 0.0284
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0283 0.0174 0.2342
Echinococcus multilocularis lysosomal alpha glucosidase 0.0232 0.014 0.0139
Loa Loa (eye worm) phosphatidylinositol kinase 0.0232 0.014 0.1305
Schistosoma mansoni zinc finger protein 0.003 0.0009 0.008
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0094 0.0051 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0007 0.0073
Schistosoma mansoni neuropeptide receptor 0.0126 0.0072 0.0664
Schistosoma mansoni biogenic amine receptor 0.0126 0.0072 0.0664
Schistosoma mansoni hypothetical protein 0.0126 0.0072 0.0664
Brugia malayi Pre-SET motif family protein 0.0035 0.0012 0.0149
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0001 0.0018
Schistosoma mansoni hypothetical protein 0.0022 0.0004 0.0029
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0722 0.0458 0.6179
Echinococcus granulosus RUN 0.0022 0.0004 0.0003
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0091 0.0049 0.0137
Brugia malayi Heterochromatin protein 1 0.0089 0.0047 0.0609
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0061 0.0029 0.0028
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0026 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0009 0.0098
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0232 0.014 0.0139
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.005 0.0022 0.0267
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0035 0.0012 0.0144
Trypanosoma brucei glycosyl hydrolase-like protein 0.0019 0.0002 0.001
Trypanosoma cruzi target of rapamycin kinase 3 0.116 0.0743 0.2129
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0067 0.0624
Mycobacterium ulcerans hypothetical protein 0.0022 0.0004 0.0205
Schistosoma mansoni cpg binding protein 0.0109 0.006 0.0559
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0126 0.0072 0.0664
Brugia malayi SET domain containing protein 0.0029 0.0008 0.0093
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0091 0.0049 0.0628
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0009 0.0008
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0026 0.0007 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0649 0.0411 0.5477
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0026 0.0325
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.119 0.0763 0.2185
Echinococcus multilocularis neuropeptide Y receptor 0.0126 0.0072 0.0071
Echinococcus granulosus neuropeptide s receptor 0.0423 0.0264 0.0263
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0011 0.0114
Echinococcus multilocularis lamin 0.0135 0.0077 0.0076
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0015 0.0014
Echinococcus multilocularis sentrin specific protease 1 0.005 0.0022 0.0021
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0011 0.0601
Mycobacterium ulcerans hypothetical protein 0.0022 0.0004 0.0197
Echinococcus multilocularis G-protein coupled receptor, putative 0.0126 0.0072 0.0071
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0015 0.0175
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0011 0.0142
Schistosoma mansoni chromobox protein 0.0089 0.0047 0.0439
Leishmania major cathepsin L-like protease 0.0049 0.0022 0.0056
Schistosoma mansoni polycystin 1-related 0.0022 0.0004 0.0029
Echinococcus multilocularis tumor protein p63 0.0434 0.0272 0.0271
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Trypanosoma brucei hypothetical protein, conserved 0.0101 0.0055 0.072
Schistosoma mansoni alpha-1 adrenergic receptor 0.0126 0.0072 0.0664
Onchocerca volvulus 0.006 0.0029 0.1687
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0126 0.0072 0.0664
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0004 0.0003
Leishmania major GTP-binding protein, putative 0.0091 0.0049 0.0131
Schistosoma mansoni coup transcription factor 0.0026 0.0007 0.0057
Loa Loa (eye worm) jmjC domain-containing protein 0.0098 0.0053 0.0495
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0006 0.0051
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0067 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Plasmodium falciparum basic transcription factor 3b, putative 0.0022 0.0004 0.0213
Echinococcus granulosus biogenic amine 5HT receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0034
Echinococcus multilocularis chromobox protein 1 0.0089 0.0047 0.0047
Echinococcus granulosus snurportin 1 0.1663 0.1069 0.1069
Echinococcus multilocularis tar DNA binding protein 0.0223 0.0135 0.0134
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0004 0.0092
Brugia malayi sulfakinin receptor protein 0.0126 0.0072 0.0925
Schistosoma mansoni smad1 5 8 and 0.0018 0.0001 0.0005
Loa Loa (eye worm) glutathione reductase 0.0136 0.0078 0.0724
Trypanosoma brucei importin beta-1 subunit, putative 0.0156 0.0091 0.1196
Brugia malayi Bromodomain containing protein 0.0043 0.0017 0.0215
Schistosoma mansoni smad 0.0018 0.0001 0.0005
Leishmania major alpha glucosidase II subunit, putative 0.0051 0.0023 0.006
Onchocerca volvulus 0.0126 0.0072 0.4394
Onchocerca volvulus 0.0126 0.0072 0.4394
Leishmania major trypanothione reductase 0.0136 0.0078 0.0211
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0283 0.0174 0.2297
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 58 nM Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligand ChEMBL. 7520943
IC50 (binding) = 58 nM Tested in vitro for the binding affinity towards NK1 receptor in human IM-9 cells using [125I]-labeled bolton-hunter substance P as ligand ChEMBL. 7520943

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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