Detailed information for compound 1691672

Basic information

Technical information
  • TDR Targets ID: 1691672
  • Name: (2S)-2-[[(8S)-1-azabicyclo[2.2.2]octan-8-yl]a mino]-N-[(3S,6S,7R,10R)-6-(cyclohexylmethyl)- 7-hydroxy-10-(morpholin-4-ylmethyl)-4,8,14-tr ioxo-1,9-dioxa-5-azacyclotetradec-3-yl]-3-phe nylpropanamide
  • MW: 725.914 | Formula: C39H59N5O8
  • H donors: 4 H acceptors: 5 LogP: 3.61 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C1CCC[C@H](CN2CCOCC2)OC(=O)[C@@H]([C@@H](NC(=O)[C@H](CO1)NC(=O)[C@@H](N[C@@H]1CN2CCC1CC2)Cc1ccccc1)CC1CCCCC1)O
  • InChi: 1S/C39H59N5O8/c45-35-13-7-12-30(24-44-18-20-50-21-19-44)52-39(49)36(46)31(22-27-8-3-1-4-9-27)41-38(48)34(26-51-35)42-37(47)32(23-28-10-5-2-6-11-28)40-33-25-43-16-14-29(33)15-17-43/h2,5-6,10-11,27,29-34,36,40,46H,1,3-4,7-9,12-26H2,(H,41,48)(H,42,47)/t30-,31+,32+,33-,34+,36-/m1/s1
  • InChiKey: KUQRLGWOANPHCW-OUOPBPENSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (2S)-N-[(3S,6S,7R,10R)-6-(cyclohexylmethyl)-7-hydroxy-10-(morpholinomethyl)-4,8,14-trioxo-1,9-dioxa-5-azacyclotetradec-3-yl]-3-phenyl-2-[[(3S)-quinuclidin-3-yl]amino]propanamide
  • (2S)-N-[(3S,6S,7R,10R)-6-(cyclohexylmethyl)-7-hydroxy-10-(morpholinomethyl)-4,8,14-trioxo-1,9-dioxa-5-azacyclotetradec-3-yl]-3-phenyl-2-[[(3S)-3-quinuclidinyl]amino]propanamide
  • (2S)-N-[(3S,6S,7R,10R)-6-(cyclohexylmethyl)-7-hydroxy-4,8,14-triketo-10-(morpholinomethyl)-1,9-dioxa-5-azacyclotetradec-3-yl]-3-phenyl-2-[[(3S)-quinuclidin-3-yl]amino]propionamide
  • (2S)-2-[[(8S)-1-azabicyclo[2.2.2]octan-8-yl]amino]-N-[(3S,6S,7R,10R)-6-(cyclohexylmethyl)-7-hydroxy-10-(morpholin-4-ylmethyl)-4,8,14-trioxo-1,9-dioxa-5-azacyclotetradec-3-yl]-3-phenyl-propanamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens renin Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Theileria parva cathepsin E, putative Get druggable targets OG5_126885 All targets in OG5_126885
Babesia bovis eukaryotic aspartyl protease family protein Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium berghei plasmepsin IV Get druggable targets OG5_126885 All targets in OG5_126885
Neospora caninum Renin, related Get druggable targets OG5_126885 All targets in OG5_126885
Candida albicans vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C) Get druggable targets OG5_126885 All targets in OG5_126885
Echinococcus granulosus cathepsin d lysosomal aspartyl protease Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Cryptosporidium hominis aspartyl protease precursor Get druggable targets OG5_126885 All targets in OG5_126885
Cryptosporidium parvum membrane bound aspartyl proteinase with a signal peptide plus transmembrane domain Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin VI Get druggable targets OG5_126885 All targets in OG5_126885
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma japonicum Cathepsin D precursor, putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin I Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium berghei plasmepsin VI Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium vivax plasmepsin IV, putative Get druggable targets OG5_126885 All targets in OG5_126885
Toxoplasma gondii aspartyl protease ASP1 Get druggable targets OG5_126885 All targets in OG5_126885
Candida albicans vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C) Get druggable targets OG5_126885 All targets in OG5_126885
Theileria parva pepsinogen, putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium knowlesi plasmepsin IV, putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin IV Get druggable targets OG5_126885 All targets in OG5_126885
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium knowlesi aspartyl protease, putative Get druggable targets OG5_126885 All targets in OG5_126885
Toxoplasma gondii aspartyl proteinase (eimepsin), putative Get druggable targets OG5_126885 All targets in OG5_126885
Neospora caninum Pepsinogen A1, related Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii plasmepsin Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin II Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma japonicum ko:K01379 cathepsin D [EC3.4.23.5], putative Get druggable targets OG5_126885 All targets in OG5_126885
Loa Loa (eye worm) aspartic protease BmAsp-2 Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium vivax aspartyl proteinase, putative Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni cathepsin D (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni cathepsin D (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum plasmepsin X renin 406 aa 352 aa 26.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.011 0.0275 0.0355
Giardia lamblia DINP protein human, muc B family 0.0021 0.0019 0.0138
Brugia malayi hypothetical protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0027 0.0035 0.019
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0039
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0037 0.0064 0.0341
Echinococcus granulosus g-protein coupled receptor 0.0068 0.0152 0.0152
Schistosoma mansoni loxhd1 0.0141 0.0362 0.0362
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0112 0.028 0.1504
Schistosoma mansoni intermediate filament proteins 0.0111 0.0276 0.0276
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0051 0.0104 0.1
Onchocerca volvulus 0.0068 0.0152 0.0195
Echinococcus multilocularis somatostatin receptor 0.0068 0.0152 0.0152
Echinococcus multilocularis cpg binding protein 0.0063 0.014 0.014
Brugia malayi prostaglandin transporter 0.0028 0.0039 0.005
Onchocerca volvulus 0.0052 0.0108 0.0138
Schistosoma mansoni neuropeptide F-like receptor 0.0068 0.0152 0.0152
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0027 0.0035 0.019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0104 0.0509
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0517 0.0517
Trypanosoma brucei glucose transporter 2A 0.0015 0.0001 0.0003
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.0059 0.0076
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0012 0.0065
Brugia malayi histone deacetylase 11 0.0134 0.0343 0.0442
Trichomonas vaginalis histone deacetylase, putative 0.0374 0.1032 0.5086
Echinococcus granulosus histone lysine methyltransferase setb 0.0092 0.0222 0.0222
Brugia malayi hypothetical protein 0.0068 0.0152 0.0196
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0104 0.0509
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0052 0.0108 0.0138
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0073 0.0166 0.1243
Echinococcus granulosus tachykinin peptides receptor 99D 0.0068 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0006 0.0034
Brugia malayi Cathepsin L-like precursor 0.0051 0.0104 0.0134
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0073 0.0166 0.1608
Brugia malayi sulfakinin receptor protein 0.0068 0.0152 0.0196
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0151 0.0392 0.0392
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0002 0.0002
Schistosoma mansoni cathepsin s 0.0017 0.0006 0.0006
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0097 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0058 0.0126 0.0162
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0002 0.0002
Loa Loa (eye worm) neuropeptide F receptor 0.0068 0.0152 0.0196
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0069 0.0335
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0027 0.0035 0.019
Echinococcus granulosus histone deacetylase 3 0.0374 0.1032 0.1032
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0374 0.1032 0.5086
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0037 0.0064 0.0341
Onchocerca volvulus 0.0045 0.0086 0.011
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0024 0.0027 0.0128
Echinococcus granulosus lipoxygenase domain containing protein 0.0141 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0028 0.0136
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.0172 0.0452 0.0452
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0138 0.0138
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) acetyltransferase 0.0144 0.0372 0.048
Trichomonas vaginalis histone deacetylase, putative 0.0374 0.1032 0.5086
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Echinococcus granulosus ecdysone induced protein 78C 0.011 0.0275 0.0275
Loa Loa (eye worm) fibroinase 0.0051 0.0104 0.0134
Onchocerca volvulus 0.0068 0.0152 0.0195
Mycobacterium ulcerans hypothetical protein 0.0045 0.0087 0.0462
Brugia malayi SET domain containing protein 0.0016 0.0004 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0801 0.395
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.0232 0.0299
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.011 0.0275 0.0275
Schistosoma mansoni glucose transport protein 0.0015 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.008 0.0187 0.0187
Echinococcus multilocularis g protein coupled receptor 0.0068 0.0152 0.0152
Echinococcus multilocularis fatty acid binding protein FABP2 0.0035 0.0058 0.0058
Echinococcus granulosus neurogenic locus notch protein 0.0479 0.1334 0.1334
Brugia malayi nuclear receptor NHR-88 0.011 0.0275 0.0355
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0139
Onchocerca volvulus 0.0095 0.0232 0.0298
Schistosoma mansoni hypothetical protein 0.0347 0.0953 0.0953
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0031 0.0296
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0019 0.0102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.0152 0.0152
Toxoplasma gondii aldo-keto reductase 0.0073 0.0166 0.1243
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0139
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0001 0.0001
Echinococcus multilocularis aldo keto reductase 0.0184 0.0486 0.0486
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0048 0.0097 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.01 0.01
Echinococcus multilocularis pyruvate kinase 0.0028 0.0038 0.0038
Onchocerca volvulus Phospholipase A2 homolog 0.0095 0.0232 0.0298
Brugia malayi Nuclear hormone receptor family member nhr-31 0.011 0.0275 0.0355
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Echinococcus granulosus neuropeptide FF receptor 2 0.0068 0.0152 0.0152
Leishmania major cathepsin L-like protease 0.0051 0.0104 0.0557
Schistosoma mansoni sugar transporter 0.0015 0.0001 0.0001
Trypanosoma cruzi aldo/keto reductase, putative 0.0184 0.0486 0.2606
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0068 0.0152 0.0152
Echinococcus multilocularis g protein coupled receptor 0.0068 0.0152 0.0152
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0374 0.1032 0.1331
Echinococcus multilocularis Ankyrin 0.0015 0.0002 0.0002
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0193 0.0513 0.2752
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.011 0.0275 0.0355
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0073 0.0166 0.1243
Toxoplasma gondii transporter, major facilitator family protein 0.0028 0.0039 0.0285
Plasmodium vivax aspartyl proteinase, putative 0.0059 0.0128 0.1231
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0007 0.0039
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0052 0.0108 0.0108
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0184 0.0486 0.0486
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Schistosoma mansoni hypothetical protein 0.0479 0.1334 0.1334
Brugia malayi ecdysteroid receptor 0.011 0.0275 0.0355
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.011 0.0275 0.0355
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0112 0.028 0.1504
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0121 0.0644
Echinococcus multilocularis ecdysone induced protein 78C 0.011 0.0275 0.0275
Echinococcus granulosus fatty acid binding protein FABP2 0.0035 0.0058 0.0058
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0055 0.0405
Trichomonas vaginalis sulfite reductase, putative 0.0027 0.0035 0.0171
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0068 0.0152 0.0152
Schistosoma mansoni laminin gamma-3 chain 0.0479 0.1334 0.1334
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0513 0.275
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0059 0.0128 0.0165
Onchocerca volvulus 0.2716 0.7755 1
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0001 0.0001
Mycobacterium ulcerans glyoxalase GloA 0.0045 0.0087 0.0462
Echinococcus granulosus cathepsin l cysteine peptidase 0.0051 0.0104 0.0104
Onchocerca volvulus Lactoylglutathione lyase homolog 0.0193 0.0513 0.0661
Schistosoma mansoni neuropeptide receptor 0.0068 0.0152 0.0152
Schistosoma mansoni tyrosine kinase 0.0081 0.0189 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0055 0.0267
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0036 0.0173
Loa Loa (eye worm) intermediate filament protein 0.0111 0.0276 0.0355
Echinococcus multilocularis neurogenic locus notch protein 0.0479 0.1334 0.1334
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0077 0.0411
Brugia malayi photoreceptor-specific nuclear receptor 0.011 0.0275 0.0355
Leishmania major hypothetical protein, conserved 0.0015 0.0001 0.0003
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0104 0.0134
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0068 0.0152 0.0152
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0048 0.0097 0.052
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0184 0.0486 0.2394
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0002
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0068 0.0152 0.0152
Loa Loa (eye worm) glutathione reductase 0.0049 0.01 0.0128
Echinococcus granulosus geminin 0.0347 0.0953 0.0953
Schistosoma mansoni hypothetical protein 0.0479 0.1334 0.1334
Brugia malayi Dopamine receptor protein 1 0.0068 0.0152 0.0196
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0059 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0077 0.0411
Mycobacterium leprae conserved hypothetical protein 0.0048 0.0097 0.0933
Loa Loa (eye worm) oxidoreductase 0.0184 0.0486 0.0627
Mycobacterium leprae conserved hypothetical protein 0.0045 0.0087 0.0691
Trypanosoma brucei histone deacetylase, putative 0.0134 0.0343 0.184
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0139
Brugia malayi Cadherin domain containing protein 0.0479 0.1334 0.1721
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0322
Echinococcus multilocularis thyroid hormone receptor alpha 0.0361 0.0995 0.0995
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0088 0.0852
Trichomonas vaginalis histone deacetylase, putative 0.0374 0.1032 0.5086
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.009 0.0218 0.0218
Toxoplasma gondii glyoxalase family protein 0.0045 0.0087 0.0645
Brugia malayi G protein-coupled receptor F59B2.13 0.0068 0.0152 0.0196
Echinococcus multilocularis serotonin receptor 0.0068 0.0152 0.0152
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0068 0.0152 0.0196
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0108 0.0108
Brugia malayi ORL1-like opioid receptor 0.0068 0.0152 0.0196
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0184 0.0486 0.0486
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0055 0.0267
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0058 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0031 0.0048 0.0062
Schistosoma mansoni slit 0.0479 0.1334 0.1334
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0007 0.0147
Echinococcus granulosus RUN 0.0141 0.0362 0.0362
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.011 0.0275 0.0275
Brugia malayi histone deacetylase 3 (HD3) 0.0374 0.1032 0.1331
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0184 0.0486 0.0627
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0092 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0104 0.0104
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0664 0.1865 1
Brugia malayi RE15519p 0.0068 0.0152 0.0196
Echinococcus multilocularis dro:myosuppressin receptor 0.0068 0.0152 0.0152
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0088 0.0852
Echinococcus multilocularis protein jagged 1 0.0479 0.1334 0.1334
Echinococcus granulosus epidermal growth factor receptor 0.0081 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0041 0.0075 0.0097
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0077 0.0411
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0068 0.0152 0.0152
Schistosoma mansoni nuclear receptor 0.0052 0.0108 0.0108
Plasmodium vivax unspecified product 0.0026 0.0033 0.0316
Schistosoma mansoni ap endonuclease 0.0057 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Brugia malayi Dopamine receptor 0.0068 0.0152 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0005
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0343 0.184
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.011 0.0275 0.0275
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0002 0.0009
Brugia malayi neuropeptide F receptor 0.0068 0.0152 0.0196
Brugia malayi putative neuropeptide receptor 0.0068 0.0152 0.0196
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0037 0.0064 0.0337
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0479 0.1334 0.1721
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Plasmodium falciparum aldehyde reductase, putative 0.0073 0.0166 0.1608
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0001 0.0001
Echinococcus granulosus thyroid hormone receptor alpha 0.0052 0.0108 0.0108
Brugia malayi nuclear receptor RXR 0.0058 0.0126 0.0162
Schistosoma mansoni amine GPCR 0.0068 0.0152 0.0152
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0039 0.0049
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0513 0.275
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0059 0.0287
Onchocerca volvulus 0.0051 0.0104 0.0133
Brugia malayi hypothetical protein 0.0052 0.0108 0.0139
Trypanosoma cruzi cysteine peptidase, putative 0.0026 0.0033 0.0178
Brugia malayi jmjC domain containing protein 0.0016 0.0003 0.0005
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0068 0.0152 0.0196
Onchocerca volvulus Neurogenic locus notch homolog 0.0479 0.1335 0.172
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0039
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0059 0.0128 0.0128
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0059 0.0128 0.0165
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0007 0.0064
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0039 0.005
Echinococcus granulosus histone deacetylase 6 0.0134 0.0343 0.0343
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0037 0.0064 0.0341
Echinococcus granulosus neuropeptide s receptor 0.1959 0.5582 0.5582
Echinococcus granulosus solute carrier family 22 0.0015 0.0001 0.0001
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0037 0.0064 0.0341
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0039 0.0049
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0001 0.0001
Echinococcus multilocularis allatostatin A receptor 0.0068 0.0152 0.0152
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.007 0.0671
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0037 0.0064 0.0337
Brugia malayi cytoplasmic intermediate filament protein 0.0059 0.0128 0.0165
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0513 0.275
Plasmodium falciparum glutathione reductase 0.0049 0.01 0.0959
Schistosoma mansoni amine GPCR 0.0068 0.0152 0.0152
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0801 0.395
Plasmodium vivax aldehyde reductase, putative 0.0073 0.0166 0.1608
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0013 0.0017
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0513 0.275
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Brugia malayi Phospholipase A2 family protein 0.0095 0.0232 0.0299
Loa Loa (eye worm) melatonin receptor type 1A 0.0068 0.0152 0.0196
Brugia malayi Histone deacetylase family protein 0.0134 0.0343 0.0442
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.0152 0.0152
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0108 0.0108
Loa Loa (eye worm) oxidoreductase 0.0184 0.0486 0.0627
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0033 0.0161
Plasmodium vivax multidomain scavenger receptor, putative 0.0141 0.0362 0.3506
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0003 0.0003
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.009 0.0116
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0343 0.184
Brugia malayi Nuclear hormone receptor family member nhr-19 0.011 0.0275 0.0355
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0027 0.0035 0.019
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0051 0.0104 0.1
Echinococcus granulosus biogenic amine 5HT receptor 0.0068 0.0152 0.0152
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0035 0.0058 0.0075
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0184 0.0486 0.0486
Brugia malayi GnHR receptor homolog 0.0068 0.0152 0.0196
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0046 0.009 0.0479
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0031 0.0229
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0322
Echinococcus granulosus neuropeptides capa receptor 0.0068 0.0152 0.0152
Trypanosoma brucei prostaglandin f synthase 0.0184 0.0486 0.2606
Schistosoma mansoni cpg binding protein 0.0063 0.014 0.014
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0033 0.0322
Brugia malayi dehydrogenases, short chain protein 2 0.0045 0.0086 0.0111
Schistosoma mansoni biogenic amine receptor 0.0068 0.0152 0.0152
Echinococcus granulosus histone deacetylase 6 0.0134 0.0343 0.0343
Echinococcus multilocularis neuropeptide receptor 0.0068 0.0152 0.0152
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0045 0.0086 0.0111
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0097 0.0237 0.0237
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.002 0.0105
Loa Loa (eye worm) hypothetical protein 0.0058 0.0126 0.0162
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.0517 0.0517
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0068 0.0152 0.0152
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0104 0.0104
Brugia malayi major facilitator superfamily protein 0.0015 0.0001 0.0001
Onchocerca volvulus 0.0051 0.0104 0.0133
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0052 0.0108 0.0108
Trypanosoma brucei glucose transporter, putative 0.0015 0.0001 0.0003
Brugia malayi Calcitonin receptor-like protein seb-1 0.0307 0.084 0.1084
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0077 0.0411
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0021 0.0021
Schistosoma mansoni tyrosine kinase 0.0048 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Brugia malayi Pre-SET motif family protein 0.0092 0.0222 0.0287
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Plasmodium vivax pyruvate kinase, putative 0.0035 0.0059 0.0565
Echinococcus granulosus neurogenic locus notch protein 4 0.0479 0.1334 0.1334
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0128 0.0128
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0026 0.0033 0.0178
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0307 0.084 0.1084
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0092 0.0222 0.0222
Leishmania major cathepsin L-like protease 0.0051 0.0104 0.0557
Entamoeba histolytica aldose reductase, putative 0.0184 0.0486 0.471
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0513 0.275
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0184 0.0486 0.0486
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0222 0.0222
Brugia malayi hypothetical protein 0.0068 0.0152 0.0196
Echinococcus granulosus aldo keto reductase 0.0184 0.0486 0.0486
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.011 0.0275 0.0355
Echinococcus granulosus G protein coupled receptor 139 0.0068 0.0152 0.0152
Onchocerca volvulus Peroxidasin homolog 0.2716 0.7755 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0007 0.0009
Brugia malayi nuclear receptor NHR-67 0.0052 0.0108 0.0139
Echinococcus granulosus alpha 1A adrenergic receptor 0.0068 0.0152 0.0152
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.0316 0.6048
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0077 0.0375
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0068 0.0152 0.0152
Schistosoma mansoni hypothetical protein 0.043 0.1192 0.1192
Echinococcus multilocularis survival motor neuron protein 1 0.0468 0.1301 0.1301
Schistosoma mansoni opsin-like receptor 0.0068 0.0152 0.0152
Trypanosoma cruzi cysteine protease, putative 0.0026 0.0033 0.0178
Onchocerca volvulus 0.0068 0.0152 0.0195
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0017
Schistosoma mansoni hypothetical protein 0.0097 0.0237 0.0237
Loa Loa (eye worm) oxidoreductase 0.0184 0.0486 0.0627
Onchocerca volvulus 0.0102 0.025 0.0322
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Brugia malayi hypothetical protein 0.0141 0.0362 0.0467
Brugia malayi Cathepsin L-like precursor 0.0051 0.0104 0.0134
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0374 0.1032 0.5086
Echinococcus granulosus insulin receptor 0.0048 0.0096 0.0096
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0007 0.0032
Trypanosoma cruzi hexose transporter 0.0015 0.0001 0.0003
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0195 0.0517 0.0666
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0007 0.0007
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0003 0.0005
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.0059 0.0076
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.013 0.0168
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0015 0.0001 0.0003
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0307 0.084 0.1084
Plasmodium falciparum plasmepsin IV 0.0059 0.0128 0.1231
Brugia malayi flavodoxin family protein 0.0027 0.0035 0.0046
Plasmodium falciparum plasmepsin I 0.0059 0.0128 0.1231
Entamoeba histolytica cysteine protease, putative 0.0051 0.0104 0.1006
Brugia malayi hypothetical protein 0.0028 0.0039 0.005
Brugia malayi jmjC domain containing protein 0.0016 0.0003 0.0005
Echinococcus multilocularis agrin 0.0019 0.0013 0.0013
Echinococcus granulosus epidermal growth factor receptor 0.015 0.0388 0.0388
Brugia malayi Furin-like cysteine rich region family protein 0.015 0.0388 0.0501
Onchocerca volvulus 0.0184 0.0486 0.0626
Brugia malayi Cytochrome P450 family protein 0.0046 0.009 0.0116
Loa Loa (eye worm) TK/EGFR protein kinase 0.015 0.0388 0.0501
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0322
Entamoeba histolytica hypothetical protein 0.0078 0.0181 0.1759
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0028 0.0039 0.0039
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0322
Echinococcus granulosus protein jagged 2 0.0479 0.1334 0.1334
Schistosoma mansoni neuropeptide F-like receptor 0.0068 0.0152 0.0152
Echinococcus granulosus pyruvate kinase 0.0018 0.001 0.001
Schistosoma mansoni cytochrome P450 reductase 0.0027 0.0035 0.0035
Echinococcus multilocularis orexin receptor type 2 0.0068 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Loa Loa (eye worm) hypothetical protein 0.0184 0.0486 0.0627
Schistosoma mansoni biogenic amine (5HT) receptor 0.0068 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0017
Toxoplasma gondii protease inhibitor PI2 0.0019 0.0013 0.0094
Echinococcus multilocularis neuropeptides capa receptor 0.0068 0.0152 0.0152
Brugia malayi Cathepsin L-like precursor 0.0051 0.0104 0.0134
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0068 0.0152 0.0152
Brugia malayi jmjC domain containing protein 0.0063 0.0138 0.0178
Brugia malayi neuropeptide F receptor 0.0068 0.0152 0.0196
Echinococcus granulosus Ankyrin repeat domain containing protein 0.009 0.0218 0.0218
Onchocerca volvulus 0.0479 0.1334 0.172
Toxoplasma gondii histone deacetylase HDAC5 0.0134 0.0343 0.2571
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0003 0.0003
Trypanosoma brucei cytochrome P450, putative 0.0046 0.009 0.0482
Trypanosoma brucei aldo/keto reductase, putative 0.0073 0.0166 0.0892
Brugia malayi lactoylglutathione lyase 0.0193 0.0513 0.0662
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0322
Onchocerca volvulus 0.0721 0.2028 0.2615
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0059 0.0075
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.0372 0.0372
Mycobacterium ulcerans pyruvate kinase 0.0035 0.0059 0.0312
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0027 0.0035 0.019
Onchocerca volvulus 0.0051 0.0104 0.0133
Brugia malayi G-protein coupled receptor 0.0068 0.0152 0.0196
Loa Loa (eye worm) hypothetical protein 0.0041 0.0075 0.0097
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0068 0.0152 0.0196
Onchocerca volvulus Chorion peroxidase homolog 0.2716 0.7755 1
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.028 0.1504
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0184 0.0486 0.0486
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.007 0.0677
Schistosoma mansoni aldo-keto reductase 0.0184 0.0486 0.0486
Loa Loa (eye worm) hypothetical protein 0.021 0.0561 0.0724
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0068 0.0152 0.0196
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0033 0.0043
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0028 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.0152 0.0152
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0104 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0061 0.03
Plasmodium falciparum LCCL domain-containing protein 0.0141 0.0362 0.3506
Plasmodium vivax vivapain-2 0.0051 0.0104 0.1
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0037 0.0064 0.0341
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0048 0.0097 0.0517
Trichomonas vaginalis set domain proteins, putative 0.0721 0.2028 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0068 0.0152 0.0152
Echinococcus multilocularis nuclear receptor nhr 48 0.0052 0.0108 0.0108
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.011 0.0275 0.0275
Onchocerca volvulus 0.0045 0.0086 0.011
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0037 0.0064 0.0337
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0068 0.0152 0.0152
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.011 0.0275 0.0355
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0019 0.0102
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0039
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0037 0.0064 0.0337
Brugia malayi Cathepsin L-like precursor 0.0051 0.0104 0.0134
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0104 0.0509
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0184 0.0486 0.0486
Loa Loa (eye worm) hypothetical protein 0.0102 0.0251 0.0323
Plasmodium falciparum nitric oxide synthase, putative 0.0027 0.0035 0.0337
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0031 0.0296
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0059 0.0128 0.0626
Loa Loa (eye worm) hypothetical protein 0.0141 0.0362 0.0467
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0195 0.0517 0.0666
Plasmodium vivax histone deacetylase 2, putative 0.0134 0.0343 0.3321
Echinococcus multilocularis aldo keto reductase 0.0184 0.0486 0.0486
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.037 0.1982
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0468 0.1301 0.1677
Trichomonas vaginalis histone deacetylase, putative 0.0374 0.1032 0.5086
Onchocerca volvulus Neuropeptide F receptor homolog 0.0068 0.0152 0.0195
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0069 0.0069
Loa Loa (eye worm) histone deacetylase 11 0.0134 0.0343 0.0442
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0007 0.0035
Echinococcus multilocularis histone deacetylase 6 0.0134 0.0343 0.0343
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.0013 0.0017
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0322
Echinococcus multilocularis dnaJ subfamily B 0.043 0.1192 0.1192
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0069 0.0368
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0001 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0048 0.0257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0061 0.03
Echinococcus granulosus phd:f box containing protein 0.0016 0.0003 0.0003
Schistosoma mansoni retinoid-x-receptor (RXR) 0.011 0.0275 0.0275
Schistosoma mansoni histone deacetylase 0.0374 0.1032 0.1032
Schistosoma mansoni 4-hydroxyphenylpyruvate dioxygenase 0.0045 0.0087 0.0087
Onchocerca volvulus Putative protein 0.0045 0.0087 0.0111
Trypanosoma brucei trypanothione reductase 0.0049 0.01 0.0534
Echinococcus granulosus neuropeptide Y receptor 0.0068 0.0152 0.0152
Brugia malayi Protein kinase domain containing protein 0.0048 0.0096 0.0123
Loa Loa (eye worm) oxidoreductase 0.0045 0.0086 0.0111
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0322
Toxoplasma gondii exonuclease III APE 0.0057 0.0121 0.09
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0007 0.0547
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0028 0.0136
Brugia malayi hypothetical protein 0.0068 0.0152 0.0196
Schistosoma mansoni pyruvate kinase 0.0035 0.0059 0.0059
Echinococcus granulosus aldo keto reductase 0.0184 0.0486 0.0486
Brugia malayi SPARC precursor 0.0019 0.0013 0.0017
Onchocerca volvulus 0.0479 0.1334 0.172
Schistosoma mansoni hypothetical protein 0.0479 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Brugia malayi Animal haem peroxidase family protein 0.2716 0.7755 1
Onchocerca volvulus 0.0052 0.0108 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0104 0.0509
Schistosoma mansoni notch 0.0479 0.1334 0.1334
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0002 0.0002
Echinococcus granulosus histone deacetylase 8 0.0134 0.0343 0.0343
Plasmodium vivax vivapain-2 0.0051 0.0104 0.1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0068 0.0152 0.0152
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0097 0.0237 0.0306
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0145
Schistosoma mansoni pol-related 0.0184 0.0486 0.0486
Schistosoma mansoni retinoic acid receptor RXR 0.0209 0.0559 0.0559
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0184 0.0486 0.0627
Brugia malayi Cathepsin L-like precursor 0.0051 0.0104 0.0134
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Brugia malayi follicle stimulating hormone receptor 0.0068 0.0152 0.0196
Onchocerca volvulus 0.011 0.0275 0.0354
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0035 0.0169
Echinococcus granulosus protein jagged 1 0.0479 0.1334 0.1334
Onchocerca volvulus Peroxidase homolog 0.2716 0.7755 1
Brugia malayi Sugar transporter family protein 0.0015 0.0001 0.0001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0088 0.0113
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0003 0.0003
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0164 0.043 0.2305
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.008 0.0391
Brugia malayi cathepsin L-like precursor 0.0034 0.0056 0.0072
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0002 0.0002
Brugia malayi EGF-like domain containing protein 0.0479 0.1334 0.1721
Trichomonas vaginalis histone deacetylase, putative 0.0374 0.1032 0.5086
Schistosoma mansoni glucose transporter 0.0015 0.0001 0.0001
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0007 0.0007
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0121 0.0156
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0002 0.0002
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0001 0.0001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.011 0.0275 0.0275
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0077 0.0411
Loa Loa (eye worm) hypothetical protein 0.011 0.0275 0.0355
Echinococcus multilocularis neuropeptide s receptor 0.1959 0.5582 0.5582
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0011 0.0011
Onchocerca volvulus 0.0068 0.0152 0.0195
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0031 0.0167
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0184 0.0486 0.2606
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0068 0.0152 0.0152
Echinococcus granulosus hypothetical protein 0.0068 0.0152 0.0152
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0097 0.0935
Loa Loa (eye worm) hypothetical protein 0.0058 0.0126 0.0162
Onchocerca volvulus 0.0045 0.0086 0.011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0513 0.275
Echinococcus granulosus tm gpcr rhodopsin 0.0068 0.0152 0.0152
Echinococcus granulosus single minded 2 0.0036 0.0062 0.0062
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0447 0.2202
Brugia malayi Nuclear hormone receptor E75 0.0052 0.0108 0.0139
Echinococcus multilocularis neurogenic locus notch protein 0.0479 0.1334 0.1334
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0037 0.0064 0.0341
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0447 0.2202
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0068 0.0152 0.0152
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0801 0.395
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0005
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0001 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0077 0.0411
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0068 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0138 0.0138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0061 0.03
Onchocerca volvulus 0.0045 0.0086 0.011
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.0152 0.0152
Plasmodium falciparum plasmepsin II 0.0059 0.0128 0.1231
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0039
Echinococcus granulosus pyruvate kinase 0.0018 0.001 0.001
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0068 0.0152 0.0152
Brugia malayi Animal haem peroxidase family protein 0.2716 0.7755 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0052 0.0108 0.0139
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0801 0.395
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0077 0.0408
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0003 0.0003
Schistosoma mansoni glucose transport protein 0.0015 0.0001 0.0001
Plasmodium falciparum aldo-keto reductase, putative 0.0073 0.0166 0.1608
Trichomonas vaginalis aldo-keto reductase, putative 0.0184 0.0486 0.2394
Giardia lamblia Nitric oxide synthase, inducible 0.0024 0.0027 0.0195
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0002 0.0009
Brugia malayi steroid hormone receptor 0.011 0.0275 0.0355
Giardia lamblia Hypothetical protein 0.0024 0.0027 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0166 0.0818
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.011 0.0275 0.0355
Brugia malayi jmjC domain containing protein 0.0059 0.0128 0.0165
Schistosoma mansoni hypothetical protein 0.0347 0.0953 0.0953
Schistosoma mansoni hypothetical protein 0.0097 0.0237 0.0237
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.026 0.0703 0.0907
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0037 0.0064 0.0337
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0447 0.2202
Onchocerca volvulus 0.0028 0.0039 0.0049
Onchocerca volvulus 0.0102 0.025 0.0322
Plasmodium falciparum thioredoxin reductase 0.0017 0.0007 0.0064
Echinococcus multilocularis serotonin receptor 0.0068 0.0152 0.0152
Echinococcus granulosus cathepsin L cysteine proteinase 0.0051 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Mycobacterium tuberculosis Probable oxidoreductase 0.0184 0.0486 0.2606
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0184 0.0486 0.0486
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0031 0.0167
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0002 0.0002
Leishmania major prostaglandin f synthase, putative 0.0184 0.0486 0.2606
Plasmodium vivax glutathione reductase, putative 0.0049 0.01 0.0959
Schistosoma mansoni neuropeptide receptor 0.0068 0.0152 0.0152
Echinococcus multilocularis solute carrier family 22 0.0015 0.0001 0.0001
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0007 0.0039
Echinococcus granulosus orexin receptor type 2 0.0068 0.0152 0.0152
Trypanosoma brucei glucose transporter, putative 0.0015 0.0001 0.0003
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0031 0.0167
Echinococcus granulosus neural cadherin 0.0479 0.1334 0.1334
Schistosoma mansoni sugar transporter 0.0015 0.0001 0.0001
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0052 0.0108 0.0139
Loa Loa (eye worm) notch protein 0.0479 0.1334 0.1721
Loa Loa (eye worm) FAD binding domain-containing protein 0.0027 0.0035 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0801 0.395
Echinococcus granulosus aldehyde reductase 0.0111 0.0278 0.0278
Echinococcus multilocularis cathepsin L 0.0026 0.0033 0.0033
Schistosoma mansoni lamin 0.0111 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0184 0.0486 0.2394
Echinococcus granulosus Solute carrier family 22 5 0.2081 0.5931 0.5931
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0007 0.0035
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.0126 0.0162
Trypanosoma cruzi major cysteine proteinase, putative 0.0152 0.0394 0.2113
Schistosoma mansoni sugar transporter 0.0015 0.0001 0.0001
Brugia malayi hypothetical protein 0.0068 0.0152 0.0196
Echinococcus multilocularis 0.0046 0.0091 0.0091
Onchocerca volvulus 0.0172 0.0452 0.0582
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0039 0.0049
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0088 0.043
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0017 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Brugia malayi Nuclear hormone receptor family member nhr-49 0.011 0.0275 0.0355
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0068 0.0152 0.0195
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0193 0.0513 0.0662
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0087 0.0424
Brugia malayi EGF-like domain containing protein 0.0479 0.1334 0.1721
Echinococcus multilocularis RUN 0.0141 0.0362 0.0362
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0037 0.0064 0.0337
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0842 0.2375 0.2375
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0172 0.0452 0.0583
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0322
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0007 0.0547
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0062 0.008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.005
Entamoeba histolytica alcohol dehydrogenase, putative 0.0073 0.0166 0.1613
Trichomonas vaginalis aldo-keto reductase, putative 0.0073 0.0166 0.0818
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0035 0.0169
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0028 0.0039 0.0039
Echinococcus multilocularis Polycystic kidney disease protein 0.0141 0.0362 0.0362
Trypanosoma brucei glucose transporter, putative 0.0015 0.0001 0.0003
Echinococcus granulosus hypothetical protein 0.0184 0.0486 0.0486
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0068 0.0152 0.0196
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0062 0.033
Schistosoma mansoni histone deacetylase 0.0374 0.1032 0.1032
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0801 0.395
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0184 0.0486 0.0486
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0045 0.022
Leishmania major trypanothione reductase 0.0049 0.01 0.0534
Trypanosoma brucei sugar transporter, putative 0.0015 0.0001 0.0003
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0007 0.0035
Echinococcus granulosus fibropellin Ia 0.0479 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Leishmania major cathepsin L-like protease 0.0193 0.0513 0.275
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Schistosoma mansoni amine GPCR 0.0068 0.0152 0.0152
Onchocerca volvulus 0.0028 0.0039 0.0049
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0001 0.0001
Echinococcus granulosus neuropeptide receptor A26 0.1959 0.5582 0.5582
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0145
Loa Loa (eye worm) hypothetical protein 0.011 0.0275 0.0355
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0104 0.0509
Brugia malayi Protein kinase domain containing protein 0.0015 0.0002 0.0002
Loa Loa (eye worm) inositol-1 0.0038 0.0069 0.0088
Echinococcus granulosus notch 0.0479 0.1334 0.1334
Entamoeba histolytica cysteine proteinase 2 0.0026 0.0033 0.0322
Toxoplasma gondii aldose reductase, putative 0.0184 0.0486 0.3639
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0104 0.0509
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0184 0.0486 0.0486
Schistosoma mansoni cathepsin D (A01 family) 0.0174 0.0458 0.0458
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.005
Schistosoma mansoni myosin xvIII 0.0068 0.0152 0.0152
Echinococcus granulosus somatostatin receptor 0.0068 0.0152 0.0152
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0322
Schistosoma mansoni tyrosine kinase 0.0048 0.0096 0.0096
Brugia malayi larval opioid receptor 0.0068 0.0152 0.0196
Schistosoma mansoni hypothetical protein 0.0015 0.0002 0.0002
Echinococcus multilocularis musashi 0.0111 0.0276 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-25 0.011 0.0275 0.0355
Echinococcus granulosus solute carrier family 22 0.0015 0.0001 0.0001
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.011 0.0275 0.0275
Schistosoma mansoni tyrosine kinase 0.008 0.0187 0.0187
Trypanosoma brucei aldo-keto reductase, putative 0.0184 0.0486 0.2606
Mycobacterium ulcerans hypothetical protein 0.0045 0.0087 0.0462
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0184 0.0486 0.2606
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0006 0.0033
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0003 0.0003
Onchocerca volvulus 0.0068 0.0152 0.0195
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0003 0.0019
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0479 0.1334 0.172
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0087 0.0209 0.0209
Entamoeba histolytica hypothetical protein 0.0078 0.0181 0.1759
Schistosoma mansoni Tr4/Tr2 (homologue) 0.011 0.0275 0.0275
Brugia malayi Nuclear hormone receptor family member nhr-41 0.011 0.0275 0.0355
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0059 0.0287
Schistosoma mansoni hypothetical protein 0.0068 0.0152 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0056 0.0272
Brugia malayi Sugar transporter family protein 0.0015 0.0001 0.0001
Echinococcus granulosus neuropeptide receptor 0.0068 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0172 0.0452 0.0583
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0513 0.275
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0139
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.0059 0.0316
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Brugia malayi G protein-coupled receptor 0.0068 0.0152 0.0196
Onchocerca volvulus 0.0028 0.0039 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0104 0.0509
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0343 0.184
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0145
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0068 0.0152 0.0152
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.008 0.008
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.0703 0.3466
Plasmodium vivax SET domain protein, putative 0.0092 0.0222 0.215
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0069 0.0337
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0068 0.0152 0.0196
Onchocerca volvulus 0.0028 0.0039 0.0049
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0088 0.0471
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0104 0.0104
Brugia malayi Cathepsin L-like precursor 0.0034 0.0056 0.0072
Schistosoma mansoni lamin 0.0111 0.0276 0.0276
Trichomonas vaginalis aldo-keto reductase, putative 0.0184 0.0486 0.2394
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0039
Leishmania major pyruvate kinase 0.0035 0.0059 0.0316
Treponema pallidum fructose-bisphosphate aldolase 0.0294 0.0801 1
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0447 0.2202
Echinococcus granulosus survival motor neuron protein 1 0.0468 0.1301 0.1301
Toxoplasma gondii cytochrome p450 superfamily protein 0.0037 0.0064 0.0472
Mycobacterium ulcerans hypothetical protein 0.0045 0.0087 0.0462
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0059 0.0316
Loa Loa (eye worm) histone deacetylase 0.0134 0.0343 0.0442
Plasmodium vivax unspecified product 0.0017 0.0006 0.0056
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0048 0.0097 0.1131
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Entamoeba histolytica hypothetical protein 0.0048 0.0097 0.0941
Loa Loa (eye worm) CYP4Cod1 0.0046 0.009 0.0116
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0121 0.0592
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.009 0.0482
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0068 0.0152 0.0196
Trypanosoma cruzi p450 reductase, putative 0.0027 0.0035 0.019
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0051 0.0104 0.0134
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.0703 0.3466
Brugia malayi tailless protein 0.0052 0.0108 0.0139
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0121 0.1164
Mycobacterium tuberculosis Probable reductase 0.0112 0.028 0.1504
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0068 0.0152 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0055 0.0267
Entamoeba histolytica alcohol dehydrogenase, putative 0.0073 0.0166 0.1613
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0343 0.184
Onchocerca volvulus Phospholipase A2 homolog 0.0095 0.0232 0.0298
Trypanosoma brucei histone deacetylase 2 0.0134 0.0343 0.184
Echinococcus granulosus neuropeptides capa receptor 0.0068 0.0152 0.0152
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0007 0.0049
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0015 0.0001 0.0001
Trichomonas vaginalis aldo-keto reductase, putative 0.0184 0.0486 0.2394
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0184 0.0486 0.0486
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0322
Leishmania major cathepsin L-like protease 0.0051 0.0104 0.0557
Onchocerca volvulus Glucosylceramidase homolog 0.017 0.0447 0.0576
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0031 0.0296
Onchocerca volvulus 0.0184 0.0486 0.0626
Echinococcus multilocularis lamin 0.0111 0.0276 0.0276
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0001 0.0001
Plasmodium falciparum pyruvate kinase 0.0035 0.0059 0.0565
Brugia malayi Histone deacetylase 1 0.0374 0.1032 0.1331
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Echinococcus granulosus fatty acid binding protein FABP2 0.0035 0.0058 0.0058
Schistosoma mansoni histone deacetylase hda2 0.0134 0.0343 0.0343
Echinococcus granulosus protein jagged 2 0.0479 0.1334 0.1334
Schistosoma mansoni cytochrome P450 0.0037 0.0064 0.0064
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0052 0.0108 0.0138
Onchocerca volvulus 0.0068 0.0152 0.0195
Plasmodium falciparum cysteine proteinase falcipain 1 0.0026 0.0033 0.0316
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0222 0.0222
Echinococcus multilocularis fmrfamide receptor 0.0068 0.0152 0.0152
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0059 0.0316
Brugia malayi Latrophilin receptor protein 2 0.0097 0.0237 0.0306
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0068 0.0152 0.0152
Leishmania major cytochrome p450-like protein 0.0046 0.009 0.0482
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0088 0.0471
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0037 0.0064 0.0337
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0007 0.0049
Brugia malayi Cathepsin L-like precursor 0.0051 0.0104 0.0134
Brugia malayi Cathepsin L-like precursor 0.0017 0.0006 0.0008
Entamoeba histolytica aldose reductase, putative 0.0184 0.0486 0.471
Trypanosoma brucei glucose transporter, putative 0.0015 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0035 0.0059 0.0076
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0447 0.2202
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0015 0.0001 0.0001
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0062 0.0062
Toxoplasma gondii histone deacetylase HDAC1 0.0134 0.0343 0.2568
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.01 0.0534
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0006 0.0008
Brugia malayi Animal haem peroxidase family protein 0.2716 0.7755 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0513 0.275
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0068 0.0152 0.0152
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.0332 0.0332
Brugia malayi Nuclear hormone receptor-like 1 0.011 0.0275 0.0355
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0037 0.0064 0.0337
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.0152 0.0152
Onchocerca volvulus 0.0051 0.0104 0.0133
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0068 0.0152 0.0196
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0068 0.0152 0.0196
Schistosoma mansoni nuclear hormone receptor 0.011 0.0275 0.0275
Trypanosoma cruzi MFS transporter, putative 0.0028 0.0039 0.0207
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0068 0.0152 0.0152
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0069 0.0368
Echinococcus multilocularis neuropeptide FF receptor 2 0.0068 0.0152 0.0152
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0057 0.0306
Brugia malayi Nuclear hormone receptor family member nhr-3 0.011 0.0275 0.0355
Schistosoma mansoni hypothetical protein 0.0015 0.0001 0.0001
Echinococcus multilocularis notch 0.0479 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.005
Echinococcus multilocularis 0.0037 0.0064 0.0064
Schistosoma mansoni histone deacetylase hda2 0.0134 0.0343 0.0343
Schistosoma mansoni sugar transporter 0.0015 0.0001 0.0001
Echinococcus multilocularis pyruvate kinase 0.0035 0.0059 0.0059
Onchocerca volvulus Bile acid receptor homolog 0.011 0.0275 0.0354
Trypanosoma brucei THT1 - hexose transporter, putative 0.0015 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0139
Trypanosoma brucei THT1 - hexose transporter, putative 0.0015 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0139
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0139
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0121 1
Onchocerca volvulus 0.0479 0.1334 0.172
Brugia malayi Nuclear hormone receptor family member nhr-14 0.011 0.0275 0.0355
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0003 0.0005
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0176 0.0465 0.2492
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0001 0.0003
Brugia malayi hypothetical protein 0.0068 0.0152 0.0196
Schistosoma mansoni follistatin 0.0019 0.0013 0.0013
Plasmodium vivax JmjC domain containing protein 0.0016 0.0003 0.0028
Schistosoma mansoni RAR-like nuclear receptor 0.011 0.0275 0.0275
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.011 0.0275 0.0355
Leishmania major histone deacetylase, putative 0.0374 0.1032 0.5532
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0005
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0003 0.0003
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0184 0.0486 0.0486
Trypanosoma cruzi cruzipain precursor, putative 0.0193 0.0513 0.275
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0027 0.0035 0.019
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0184 0.0486 0.0486
Brugia malayi Cadherin domain containing protein 0.0479 0.1334 0.1721
Echinococcus granulosus g protein coupled receptor 0.0068 0.0152 0.0152
Leishmania major hypothetical protein, conserved 0.0025 0.0031 0.0167
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0088 0.0113
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0001 0.0003
Brugia malayi EGF-like domain containing protein 0.0479 0.1334 0.1721
Loa Loa (eye worm) G-protein coupled receptor 0.0068 0.0152 0.0196
Onchocerca volvulus 0.0019 0.0013 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0039
Loa Loa (eye worm) blistered cuticle protein 3 0.2716 0.7755 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0003 0.0019
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0048 0.0097 0.0723
Leishmania major pyruvate kinase 0.0035 0.0059 0.0316
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0104 0.0557
Schistosoma mansoni amine GPCR 0.0068 0.0152 0.0152
Leishmania major DNA polymerase kappa, putative 0.0021 0.0019 0.0102
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0028 0.0039 0.005
Loa Loa (eye worm) histone deacetylase 1 0.0374 0.1032 0.1331
Schistosoma mansoni cathepsin D (A01 family) 0.0174 0.0458 0.0458
Trypanosoma brucei hypothetical protein, conserved 0.0048 0.0097 0.052
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Onchocerca volvulus 0.0068 0.0152 0.0195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0513 0.275
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0184 0.0486 0.0486
Brugia malayi hypothetical protein 0.0068 0.0152 0.0196
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0343 0.184
Giardia lamblia GTOR 0.0045 0.0088 0.0654
Schistosoma mansoni neuropeptide receptor 0.0068 0.0152 0.0152
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0374 0.1032 0.5086
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0053 0.0111 0.0111
Mycobacterium ulcerans hypothetical protein 0.0045 0.0087 0.0462
Brugia malayi conserved hypotetical protein 0.0052 0.0108 0.0139
Schistosoma mansoni nuclear receptor 0.0052 0.0108 0.0108
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0251 0.0679 0.0679
Leishmania major cytochrome p450-like protein 0.0037 0.0064 0.0341
Echinococcus granulosus FTZ F1 alpha 0.011 0.0275 0.0275
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0003 0.0021
Brugia malayi nuclear hormone receptor family member odr-7 0.0052 0.0108 0.0139
Brugia malayi Dopamine receptor protein 2 0.0068 0.0152 0.0196
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0033 0.0178
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0121 0.0647
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Giardia lamblia Aldose reductase 0.0184 0.0486 0.3639
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0078 0.0181 0.0181
Schistosoma mansoni hypothetical protein 0.0479 0.1334 0.1334
Trypanosoma cruzi histone deacetylase 1, putative 0.0374 0.1032 0.5532
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0037 0.0064 0.0337
Schistosoma mansoni hypothetical protein 0.0068 0.0152 0.0152
Loa Loa (eye worm) DR-78 0.0052 0.0108 0.0139
Echinococcus granulosus delta-like protein 1 0.0479 0.1334 0.1334
Schistosoma mansoni tyrosine kinase 0.008 0.0187 0.0187
Leishmania major cathepsin L-like protease 0.0193 0.0513 0.275
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0139
Echinococcus granulosus Ankyrin 0.0015 0.0002 0.0002
Echinococcus multilocularis G protein coupled receptor 139 0.0068 0.0152 0.0152
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0027 0.0035 0.0035
Toxoplasma gondii histone deacetylase HDAC2 0.0374 0.1032 0.7732
Brugia malayi Nuclear hormone receptor family member nhr-40 0.011 0.0275 0.0355
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0069 0.0665
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.002 0.0026
Schistosoma mansoni biogenic amine (5HT) receptor 0.0068 0.0152 0.0152
Schistosoma mansoni hypothetical protein 0.0095 0.0232 0.0232
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0322
Schistosoma mansoni hypothetical protein 0.021 0.0561 0.0561
Echinococcus multilocularis histone deacetylase 0.0134 0.0343 0.0343
Echinococcus multilocularis g protein coupled receptor 0.0068 0.0152 0.0152
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0104 0.0134
Leishmania major cathepsin L-like protease 0.0051 0.0104 0.0557
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0033 0.0178
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0033 0.0033
Onchocerca volvulus Histone deacetylase 10 homolog 0.0134 0.0343 0.0442
Echinococcus multilocularis protein jagged 1 0.0479 0.1334 0.1334
Brugia malayi notch-like transmembrane receptor 0.0479 0.1334 0.1721
Trypanosoma cruzi histone deacetylase 1, putative 0.0374 0.1032 0.5532
Echinococcus granulosus Nuclear hormone receptor HR96 0.0052 0.0108 0.0108
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0473 0.2332
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0007 0.0049
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.0316 0.1697
Onchocerca volvulus 0.0045 0.0086 0.011
Echinococcus granulosus nuclear receptor nhr 48 0.0052 0.0108 0.0108
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.0517 0.0517
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.0801 0.7767
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0209 0.0559 0.0559
Loa Loa (eye worm) oxidoreductase 0.0184 0.0486 0.0627
Schistosoma mansoni notch 0.0479 0.1334 0.1334
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.0152 0.0152
Echinococcus granulosus allatostatin A receptor 0.0068 0.0152 0.0152
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0033 0.0322
Mycobacterium leprae Conserved hypothetical protein 0.0111 0.0278 0.5147
Schistosoma mansoni thyroid hormone receptor 0.0361 0.0995 0.0995
Plasmodium vivax histone deacetylase, putative 0.0134 0.0343 0.3321
Toxoplasma gondii histone deacetylase HDAC3 0.0374 0.1032 0.7732
Schistosoma mansoni hypothetical protein 0.0479 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.011 0.0275 0.0355
Loa Loa (eye worm) ctsf protein 0.0051 0.0104 0.0134
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.0372 0.048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0055 0.0267
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.0072
Loa Loa (eye worm) nuclear hormone receptor 0.0052 0.0108 0.0139
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0077 0.0375
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0007 0.0064
Echinococcus granulosus cytochrome P450 2K1 0.0037 0.0064 0.0064
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0002 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.0058 0.0126 0.0162
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0007 0.0039
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0037 0.0064 0.0341
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0007 0.0007
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0058 0.0126 0.0126
Mycobacterium tuberculosis Conserved hypothetical protein 0.0045 0.0087 0.0465
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0001 0.0003
Trichomonas vaginalis aldo/keto reductase, putative 0.0184 0.0486 0.2394
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0073 0.0166 0.0215
Leishmania major cytochrome P450 reductase, putative 0.0024 0.0027 0.0143
Brugia malayi Nuclear hormone receptor family member nhr-25 0.011 0.0275 0.0355
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0013 0.0017
Plasmodium falciparum histone deacetylase, putative 0.0134 0.0343 0.3321
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0447 0.2202
Loa Loa (eye worm) hypothetical protein 0.0041 0.0075 0.0097
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0088 0.0471
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Loa Loa (eye worm) Notch2 0.0479 0.1334 0.1721
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0037 0.0064 0.0337
Echinococcus multilocularis neuropeptide receptor A26 0.1959 0.5582 0.5582
Brugia malayi hypothetical protein 0.0468 0.1301 0.1677
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0801 0.395
Loa Loa (eye worm) latrophilin receptor protein 2 0.0097 0.0237 0.0306
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0088 0.0471
Schistosoma mansoni biogenic amine receptor 0.0068 0.0152 0.0152
Brugia malayi hypothetical protein 0.0141 0.0362 0.0467
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0046
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0513 0.275
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0005
Schistosoma mansoni histamine h1 receptor 0.0068 0.0152 0.0152
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0001 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0006 0.0033
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0002 0.0009
Brugia malayi N-terminal motif family protein 0.0208 0.0554 0.0715
Echinococcus multilocularis slit 2 protein 0.0479 0.1334 0.1334
Echinococcus granulosus lamin 0.0111 0.0276 0.0276
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0033 0.0178
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0513 0.275
Brugia malayi intermediate filament protein 0.0111 0.0276 0.0355
Plasmodium vivax flavodoxin domain containing protein 0.0024 0.0027 0.0252
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0037 0.0064 0.0337
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0052 0.0108 0.0108
Echinococcus granulosus neurogenic locus protein delta 0.0479 0.1334 0.1334
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.018 0.018
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0184 0.0486 0.2394
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0048 0.0097 0.0517
Schistosoma mansoni histone deacetylase 4 5 0.0134 0.0343 0.0343
Mycobacterium ulcerans hypothetical protein 0.0073 0.0166 0.0889
Schistosoma mansoni glucose transport protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Loa Loa (eye worm) cysteine protease 0.0051 0.0104 0.0134
Onchocerca volvulus Peroxidase homolog 0.2716 0.7755 1
Schistosoma mansoni biogenic amine receptor 0.0068 0.0152 0.0152
Mycobacterium ulcerans oxidoreductase 0.0184 0.0486 0.2603
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0037 0.0064 0.0341
Schistosoma mansoni notch 0.0479 0.1335 0.1335
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0002 0.0009
Onchocerca volvulus 0.0111 0.0276 0.0355
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0121 0.1169
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0088 0.043
Schistosoma mansoni pyruvate kinase 0.0018 0.001 0.001
Onchocerca volvulus 0.0036 0.0062 0.0079
Echinococcus multilocularis neuropeptide receptor 0.0068 0.0152 0.0152
Trypanosoma brucei histone deacetylase 4 0.0134 0.0343 0.184
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0128 0.0128
Echinococcus granulosus nuclear receptor 2DBD gamma 0.011 0.0275 0.0275
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Echinococcus multilocularis histone deacetylase 7 0.0134 0.0343 0.0343
Mycobacterium ulcerans hypothetical protein 0.0045 0.0087 0.0462
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0061 0.033
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0048 0.0096 0.0096
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0184 0.0486 0.0486
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.0801 0.395
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0184 0.0486 0.2394
Schistosoma mansoni rab6-interacting 0.0141 0.0362 0.0362
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0222 0.0222
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0035 0.0058 0.0075
Schistosoma mansoni lipoxygenase 0.0842 0.2375 0.2375
Leishmania major aldo-keto reductase-like protein 0.0184 0.0486 0.2606
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.0703 0.3466
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.005
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0184 0.0486 0.0486
Echinococcus multilocularis cysteine protease 0.0051 0.0104 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0036 0.0173
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0052 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Trypanosoma brucei glucose transporter 1E 0.0015 0.0001 0.0003
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3421 0.9779 0.9779
Echinococcus multilocularis geminin 0.0347 0.0953 0.0953
Brugia malayi nuclear receptor NHR-88 0.0052 0.0108 0.0139
Brugia malayi Pre-SET motif family protein 0.0634 0.1777 0.2292
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Trypanosoma brucei glucose transporter, putative 0.0015 0.0001 0.0003
Brugia malayi hypothetical protein 0.0015 0.0001 0.0001
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0068 0.0152 0.0152
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0092 0.0222 0.1663
Chlamydia trachomatis pyruvate kinase 0.0035 0.0059 0.5813
Brugia malayi GCC2 and GCC3 family protein 0.0479 0.1334 0.1721
Brugia malayi hypothetical protein 0.0045 0.0086 0.0111
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0009 0.0042
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0045 0.0086 0.0111
Brugia malayi Peroxidasin 0.2716 0.7755 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.0361 0.0361
Echinococcus multilocularis histone deacetylase 6 0.0134 0.0343 0.0343
Mycobacterium ulcerans epoxide hydrolase EphA 0.0164 0.043 0.2302
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0001 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0104 0.1006
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0108 0.0108
Echinococcus multilocularis histone deacetylase 8 0.0134 0.0343 0.0343
Echinococcus granulosus dro:myosuppressin receptor 0.0068 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Mycobacterium leprae putative cytochrome p450 0.0037 0.0064 0.0152
Toxoplasma gondii cathepsin CPL 0.0051 0.0104 0.0774
Echinococcus multilocularis histone deacetylase 6 0.0134 0.0343 0.0343
Schistosoma mansoni polycystin 1-related 0.0141 0.0362 0.0362
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.009 0.0116
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.008 0.0595
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0184 0.0486 1
Onchocerca volvulus 0.0111 0.0276 0.0355
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0061 0.03
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0058 0.0126 0.0126
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0015 0.0001 0.0001
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0128 0.0128
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0121 0.0647
Brugia malayi Animal haem peroxidase family protein 0.2716 0.7755 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.011 0.0275 0.0355
Brugia malayi 4-hydroxyphenylpyruvate dioxygenase family protein 0.0045 0.0087 0.0112
Trichomonas vaginalis aldo-keto reductase, putative 0.0184 0.0486 0.2394
Echinococcus multilocularis fmrfamide receptor 0.0068 0.0152 0.0152
Echinococcus granulosus nuclear receptor 2DBD gamma 0.011 0.0275 0.0275
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.026 0.0703 0.0907
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.011 0.0275 0.0355
Echinococcus multilocularis pyruvate kinase 0.0018 0.001 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0002 0.0002
Brugia malayi major facilitator superfamily protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Brugia malayi hypothetical protein 0.0052 0.0108 0.0139
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0003 0.0005
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0061 0.033
Brugia malayi hypothetical protein 0.0068 0.0152 0.0196
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0011 0.0011
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0218 0.0218
Onchocerca volvulus 0.0068 0.0152 0.0195
Brugia malayi Melatonin receptor type 1A 0.0068 0.0152 0.0196
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0218 0.0218
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0059 0.0076
Loa Loa (eye worm) sugar transporter 0.0015 0.0001 0.0001
Echinococcus granulosus 7TM GPCR rhodopsin 0.0068 0.0152 0.0152
Echinococcus granulosus L aminoadipate semialdehyde 0.0172 0.0452 0.0452
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0104 0.0509
Trichomonas vaginalis histone deacetylase, putative 0.0374 0.1032 0.5086
Echinococcus granulosus pyruvate kinase 0.0018 0.001 0.001
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0664 0.1865 1
Echinococcus granulosus lamin dm0 0.0111 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Entamoeba histolytica aldose reductase, putative 0.0184 0.0486 0.471
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0002 0.0002
Echinococcus granulosus neurogenic locus notch protein 0.0479 0.1334 0.1334
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0001 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0013 0.0094
Echinococcus granulosus dnaJ subfamily B 0.043 0.1192 0.1192
Brugia malayi Serotonin receptor 0.0068 0.0152 0.0196
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.001 0.0069
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0037 0.0064 0.0341
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0634 0.1777 0.2292
Echinococcus granulosus intermediate filament protein 0.0111 0.0276 0.0276
Brugia malayi M-phase phosphoprotein, mpp8 0.0102 0.025 0.0323
Trypanosoma brucei THT1 - hexose transporter, putative 0.0015 0.0001 0.0003
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0001 0.0003
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0053 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.004
Loa Loa (eye worm) nuclear receptor NHR-67 0.0052 0.0108 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0036 0.0173
Toxoplasma gondii aspartyl protease ASP1 0.0059 0.0128 0.0952
Brugia malayi Serotonin receptor 0.0068 0.0152 0.0196
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Echinococcus multilocularis lamin dm0 0.0111 0.0276 0.0276
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0068 0.0152 0.0152
Onchocerca volvulus 0.0479 0.1334 0.172
Echinococcus granulosus agrin 0.0019 0.0013 0.0013
Plasmodium falciparum glyoxalase I 0.0193 0.0513 0.4972
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0002 0.0002
Loa Loa (eye worm) animal heme peroxidase 0.2716 0.7755 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0068 0.0152 0.0152
Loa Loa (eye worm) 4-hydroxyphenylpyruvate dioxygenase 0.0045 0.0087 0.0112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.0152 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0006 0.0033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0517 0.0517
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0033 0.0033
Echinococcus multilocularis protein jagged 2 0.0479 0.1334 0.1334
Plasmodium falciparum cysteine proteinase falcipain 3 0.0051 0.0104 0.1
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0059 0.0075
Plasmodium vivax histone deacetylase, putative 0.0134 0.0343 0.3321
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.011 0.0275 0.0354
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0003 0.0003
Schistosoma mansoni histone deacetylase 1 2 3 0.0134 0.0343 0.0343
Echinococcus granulosus pyruvate kinase 0.0035 0.0059 0.0059
Brugia malayi Calcium binding EGF domain containing protein 0.0479 0.1334 0.1721
Echinococcus multilocularis sex peptide receptor 0.0068 0.0152 0.0152
Echinococcus granulosus biogenic amine 5HT receptor 0.0068 0.0152 0.0152
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0193 0.0513 0.2752
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0664 0.1865 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0184 0.0486 0.2394
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0001 0.0001
Echinococcus multilocularis neural cadherin 0.0479 0.1334 0.1334
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.011 0.0275 0.0275
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0013 0.0017
Onchocerca volvulus 0.0068 0.0152 0.0195
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0037 0.0064 0.0337
Echinococcus granulosus solute carrier family 22 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0005
Echinococcus granulosus histone deacetylase 6 0.0134 0.0343 0.0343
Echinococcus granulosus Solute carrier organic anion transporter family 0.0028 0.0039 0.0039
Echinococcus granulosus voltage gated potassium channel subunit 0.0073 0.0166 0.0166
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.037 0.1985
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0077 0.0411
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0059 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0058 0.0126 0.0162
Schistosoma mansoni pyruvate kinase 0.0035 0.0059 0.0059
Brugia malayi EGF-like domain containing protein 0.0479 0.1334 0.1721
Onchocerca volvulus 0.0184 0.0486 0.0626
Loa Loa (eye worm) hypothetical protein 0.0041 0.0075 0.0097
Entamoeba histolytica hypothetical protein 0.0078 0.0181 0.1759
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0037 0.0064 0.0341
Onchocerca volvulus 0.0068 0.0152 0.0195
Onchocerca volvulus 0.0068 0.0152 0.0195
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Toxoplasma gondii histone deacetylase HDAC4 0.0134 0.0343 0.2568
Echinococcus multilocularis neurogenic locus protein delta 0.0479 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0145
Mycobacterium tuberculosis Conserved protein TB27.3 0.0045 0.0087 0.0465
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Loa Loa (eye worm) hypothetical protein 0.0095 0.0232 0.0299
Brugia malayi Animal haem peroxidase family protein 0.2716 0.7755 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0184 0.0486 0.0486
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.011 0.0275 0.0275
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0068 0.0152 0.0152
Echinococcus granulosus dna polymerase kappa 0.0041 0.0077 0.0077
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0059 0.0075
Brugia malayi Cytochrome P450 family protein 0.0037 0.0064 0.0082
Trypanosoma brucei pyruvate kinase 1 0.0035 0.0059 0.0316
Brugia malayi hypothetical protein 0.0028 0.0039 0.005
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0061 0.033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0077 0.0411
Loa Loa (eye worm) hypothetical protein 0.0102 0.025 0.0323
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0184 0.0486 0.0486
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.0703 0.3466
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0011 0.0011
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0447 0.2202
Mycobacterium ulcerans glyoxalase GloA 0.0045 0.0087 0.0462
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0059 0.0128 0.0952
Plasmodium falciparum plasmepsin VI 0.0059 0.0128 0.1231
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.011 0.0275 0.0275
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0104 0.0133
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0059 0.0128 0.0165
Loa Loa (eye worm) cytochrome P450 family protein 0.0076 0.0176 0.0227
Onchocerca volvulus 0.0479 0.1334 0.172
Toxoplasma gondii thioredoxin reductase 0.0049 0.01 0.0741
Leishmania major glucose transporter, lmgt2 0.0015 0.0001 0.0003
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0027 0.0035 0.0035
Brugia malayi Sugar transporter family protein 0.0015 0.0001 0.0001
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0033 0.0043
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.0059 0.0316
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0104 0.1006
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0088 0.0471
Loa Loa (eye worm) hypothetical protein 0.0058 0.0126 0.0162
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0037 0.0064 0.0341
Onchocerca volvulus 0.0073 0.0166 0.0214
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0048 0.0096 0.0096
Echinococcus multilocularis solute carrier family 22 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0134 0.0343 0.0442
Echinococcus multilocularis neurogenic locus protein delta 0.0479 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Brugia malayi Nuclear hormone receptor family member nhr-19 0.011 0.0275 0.0355
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0103 0.0255 0.0255
Mycobacterium tuberculosis Conserved protein 0.0073 0.0166 0.0892
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0027 0.0035 0.019
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0039 0.005
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0027 0.0035 0.0337
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0088 0.0088
Brugia malayi hypoxia-induced factor 1 0.0151 0.0393 0.0506
Onchocerca volvulus Slit protein homolog 0.0479 0.1334 0.172
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.0152 0.0152
Echinococcus granulosus histone deacetylase 1 0.0374 0.1032 0.1032
Echinococcus multilocularis aldo keto reductase 0.0184 0.0486 0.0486
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0028 0.0136
Mycobacterium tuberculosis Conserved protein 0.0045 0.0087 0.0465
Echinococcus multilocularis pyruvate kinase 0.0018 0.001 0.001
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0037 0.0064 0.0341
Brugia malayi AKH receptor 0.0068 0.0152 0.0196
Onchocerca volvulus 0.0141 0.0362 0.0466
Schistosoma mansoni nuclear receptor nhr-48 0.0052 0.0108 0.0108
Leishmania major cathepsin L-like protease 0.0193 0.0513 0.275
Echinococcus multilocularis FTZ F1 alpha 0.011 0.0275 0.0275
Plasmodium vivax histone deacetylase 1, putative 0.0374 0.1032 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0013 0.0094
Echinococcus multilocularis aldo keto reductase 0.0184 0.0486 0.0486
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0069 0.0069
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0056 0.0056
Trichomonas vaginalis aldo/keto reductase, putative 0.0184 0.0486 0.2394
Echinococcus multilocularis lipoxygenase domain containing protein 0.0141 0.0362 0.0362
Trypanosoma cruzi aldo/keto reductase, putative 0.0073 0.0166 0.0892
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.0059 0.0043
Brugia malayi polk-prov protein 0.0031 0.0048 0.0062
Giardia lamblia Pyruvate kinase 0.0018 0.001 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0001 0.0001
Schistosoma mansoni agrin 0.0019 0.0013 0.0013
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0077 0.0077
Echinococcus granulosus aldo keto reductase 0.0184 0.0486 0.0486
Schistosoma mansoni hypothetical protein 0.0097 0.0237 0.0237
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0003 0.0003
Schistosoma mansoni neuropeptide receptor 0.0068 0.0152 0.0152
Trichomonas vaginalis aldo-keto reductase, putative 0.0184 0.0486 0.2394
Brugia malayi Cytochrome P450 family protein 0.0076 0.0176 0.0227
Brugia malayi Cathepsin L-like precursor 0.0034 0.0056 0.0072
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0068 0.0152 0.0196
Echinococcus granulosus neuropeptide Y receptor 0.0068 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0028 0.0136
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0145
Echinococcus multilocularis insulin receptor 0.0048 0.0096 0.0096
Echinococcus multilocularis neuropeptides capa receptor 0.0068 0.0152 0.0152
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0322
Onchocerca volvulus 0.0141 0.0362 0.0466
Schistosoma mansoni hypothetical protein 0.0078 0.0181 0.0181
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0015 0.0001 0.0001
Brugia malayi hypothetical protein 0.0068 0.0152 0.0196
Trichomonas vaginalis aldo-keto reductase, putative 0.0073 0.0166 0.0818
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0121 0.1428
Echinococcus granulosus Polycystic kidney disease protein 0.0141 0.0362 0.0362
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0069 0.0335
Plasmodium falciparum histone deacetylase 2 0.0134 0.0343 0.3321
Schistosoma mansoni hypothetical protein 0.0479 0.1334 0.1334
Echinococcus multilocularis histone deacetylase 1 0.0374 0.1032 0.1032
Giardia lamblia Pyruvate kinase 0.0035 0.0059 0.0437
Brugia malayi PAS domain containing protein 0.0049 0.0099 0.0127
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0048 0.0097 0.8035
Brugia malayi nuclear receptor RXR 0.0052 0.0108 0.0139
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0045 0.0086 0.046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.011 0.0275 0.0355
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0184 0.0486 0.0627
Echinococcus multilocularis GPCR, family 2 0.0097 0.0237 0.0237
Trypanosoma brucei histone deacetylase 1 0.0374 0.1032 0.5532
Echinococcus granulosus sex peptide receptor 0.0068 0.0152 0.0152
Toxoplasma gondii histone lysine methyltransferase SET1 0.012 0.0304 0.2272
Schistosoma mansoni ap endonuclease 0.0057 0.0121 0.0121
Onchocerca volvulus Dual oxidase homolog 0.2716 0.7755 1
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0104 0.0509
Brugia malayi EGF-like domain containing protein 0.0479 0.1334 0.1721
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0045 0.0086 0.0111
Schistosoma mansoni fatty acid binding protein 0.0035 0.0058 0.0058
Brugia malayi hypothetical protein 0.0102 0.0251 0.0323
Echinococcus granulosus protein jagged 1 0.0479 0.1334 0.1334
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.0703 0.3466
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Echinococcus granulosus neuropeptide receptor 0.0068 0.0152 0.0152
Schistosoma mansoni septate junction protein 0.0479 0.1334 0.1334
Brugia malayi hypothetical protein 0.0058 0.0126 0.0162
Schistosoma mansoni aldo-keto reductase 0.0184 0.0486 0.0486
Schistosoma mansoni tyrosine kinase 0.015 0.0388 0.0388
Loa Loa (eye worm) histone deacetylase 7A 0.0134 0.0343 0.0442
Trichomonas vaginalis aldo-keto reductase, putative 0.0184 0.0486 0.2394
Echinococcus granulosus pyruvate kinase 0.0035 0.0059 0.0059
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.0517 0.0517
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0019 0.0102
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0008
Mycobacterium tuberculosis Conserved protein 0.0045 0.0087 0.0465
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0077 0.0411
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0037 0.0064 0.0341
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0003 0.0019
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0172 0.0452 0.0452
Brugia malayi CXXC zinc finger family protein 0.006 0.013 0.0168
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0011 0.0011
Schistosoma mansoni cpg binding protein 0.006 0.013 0.013
Brugia malayi hypothetical protein 0.0068 0.0152 0.0196
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0059 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0045 0.0086 0.0642
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0513 0.275
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0087 0.0424
Onchocerca volvulus Cathepsin F homolog 0.0051 0.0104 0.0133
Brugia malayi cathepsin F-like cysteine proteinase 0.0017 0.0006 0.0008
Leishmania major hypothetical protein, conserved 0.0016 0.0003 0.0019
Leishmania major histone deacetylase, putative 0.0134 0.0343 0.184
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0027 0.0035 0.0186
Loa Loa (eye worm) hypothetical protein 0.0097 0.0237 0.0306
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.0316 0.1697
Mycobacterium leprae Conserved hypothetical protein 0.0037 0.0064 0.0152
Trichomonas vaginalis aldo-keto reductase, putative 0.0184 0.0486 0.2394
Schistosoma mansoni hypothetical protein 0.0068 0.0152 0.0152
Schistosoma mansoni thyroid hormone receptor 0.0361 0.0995 0.0995
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0517 0.0517
Leishmania major histone deacetylase, putative 0.0134 0.0343 0.184
Echinococcus multilocularis neuropeptide Y receptor 0.0068 0.0152 0.0152
Onchocerca volvulus 0.0184 0.0486 0.0626
Leishmania major glucose transporter/membrane transporter D2, putative 0.0015 0.0001 0.0003
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0068 0.0152 0.0152
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0208 0.0554 0.0714
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0069 0.0335
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0015 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0039 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0033 0.0161
Onchocerca volvulus 0.0068 0.0152 0.0195
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0104 0.0104
Brugia malayi Calcium binding EGF domain containing protein 0.0479 0.1334 0.1721
Trypanosoma brucei DNA polymerase IV, putative 0.0035 0.0058 0.0309
Leishmania major p450 reductase, putative 0.0027 0.0035 0.019
Onchocerca volvulus 0.2716 0.7755 1
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0002 0.0009
Brugia malayi Muscle positioning protein 4 0.0479 0.1334 0.1721
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0068 0.0152 0.0152
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.0517 0.0517
Echinococcus granulosus tm gpcr rhodopsin 0.0068 0.0152 0.0152
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.0801 0.7767
Loa Loa (eye worm) FAD binding domain-containing protein 0.0017 0.0006 0.0008
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0027 0.0035 0.0035
Mycobacterium leprae Possible oxidoreductase 0.0073 0.0166 0.255
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0058 0.0126 0.0162
Loa Loa (eye worm) animal heme peroxidase 0.2716 0.7755 1
Echinococcus multilocularis neuropeptide Y receptor 0.0068 0.0152 0.0152
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0007 0.0039
Leishmania major protein kinase, putative 0.0017 0.0008 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0037 0.0064 0.0341
Leishmania major histone deacetylase, putative 0.0374 0.1032 0.5532
Brugia malayi Calcium binding EGF domain containing protein 0.0479 0.1334 0.1721
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.001 0.009
Giardia lamblia Fructose-bisphosphate aldolase 0.0294 0.0801 0.6005
Onchocerca volvulus 0.2716 0.7755 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.0276 0.0355
Mycobacterium ulcerans hypothetical protein 0.0045 0.0087 0.0462
Giardia lamblia Histone deacetylase 0.0374 0.1032 0.7732
Brugia malayi nuclear hormone receptor family member nhr-6 0.0052 0.0108 0.0139
Brugia malayi ecdysone receptor 0.0052 0.0108 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0055 0.0267
Loa Loa (eye worm) oxidoreductase 0.0184 0.0486 0.0627
Echinococcus multilocularis solute carrier family 22 0.0015 0.0001 0.0001
Trypanosoma brucei glucose transporter, putative 0.0015 0.0001 0.0003
Plasmodium falciparum glutathione reductase 0.0017 0.0007 0.0064
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Echinococcus granulosus peptide allatostatin:somatostatin 0.0068 0.0152 0.0152
Brugia malayi glutathione reductase 0.0049 0.01 0.0128
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.028 0.1504
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.0013 0.0017
Schistosoma mansoni hypothetical protein 0.0141 0.0362 0.0362
Trichomonas vaginalis aldo-keto reductase, putative 0.0073 0.0166 0.0818
Schistosoma mansoni amine GPCR 0.0068 0.0152 0.0152
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.008 0.0595
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.0372 0.0372
Brugia malayi cytochrome P450 0.0037 0.0064 0.0082
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0139
Schistosoma mansoni microtubule-associated protein tau 0.3498 1 1
Echinococcus granulosus cathepsin L 0.0026 0.0033 0.0033
Schistosoma mansoni tyrosine kinase 0.0081 0.0189 0.0189
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0473 0.2332
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0003 0.0003
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0097 0.0237 0.0237
Brugia malayi Intermediate filament tail domain containing protein 0.0111 0.0276 0.0355
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0139
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0003 0.0003
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0003 0.0003
Giardia lamblia High cysteine protein 0.0479 0.1334 1
Echinococcus granulosus cpg binding protein 0.0063 0.014 0.014
Giardia lamblia Aldose reductase 0.0184 0.0486 0.3639
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0056 0.054
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0121 0.09
Schistosoma mansoni organic anion transporter 0.0028 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0139
Leishmania major phosphopantetheinyl transferase-like protein 0.0048 0.0097 0.052
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.0703 0.3466
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0145
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.011 0.0275 0.0275
Echinococcus multilocularis cysteine protease 0.0051 0.0104 0.0104
Echinococcus granulosus histone deacetylase 7 0.0134 0.0343 0.0343
Brugia malayi nuclear hormone receptor 0.0052 0.0108 0.0139
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Brugia malayi hypothetical protein 0.0068 0.0152 0.0196
Plasmodium vivax vivapain-1 0.0026 0.0033 0.0316
Brugia malayi Thioredoxin reductase 0.0049 0.01 0.0128
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0111 0.0276 0.0355
Loa Loa (eye worm) histone deacetylase 3 0.0374 0.1032 0.1331
Onchocerca volvulus 0.0051 0.0104 0.0133
Toxoplasma gondii glyoxalase I, putative 0.0193 0.0513 0.3844
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0055 0.0267
Loa Loa (eye worm) hypothetical protein 0.0208 0.0554 0.0715
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0007 0.0039
Leishmania major glyoxalase I,trypanothione-dependent glyoxalase I 0.0193 0.0513 0.2752
Brugia malayi FAD binding domain containing protein 0.0027 0.0035 0.0046
Loa Loa (eye worm) hypothetical protein 0.011 0.0275 0.0355
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0088 0.0471
Echinococcus granulosus fmrfamide receptor 0.0068 0.0152 0.0152
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0121 0.0156
Leishmania major cathepsin L-like protease 0.0051 0.0104 0.0557
Onchocerca volvulus 0.0051 0.0104 0.0133
Brugia malayi nuclear hormone receptor 0.011 0.0275 0.0355
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0078 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.005
Schistosoma mansoni gynecophoral canal protein 0.0045 0.0087 0.0087
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0033 0.0033
Echinococcus granulosus g protein coupled receptor 0.0068 0.0152 0.0152
Schistosoma mansoni hypothetical protein 0.0068 0.0152 0.0152
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0322
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0068 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.011 0.0275 0.0355
Echinococcus granulosus Nuclear hormone receptor HR96 0.0052 0.0108 0.0108
Loa Loa (eye worm) cytochrome P450 0.0037 0.0064 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0077 0.0411
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.011 0.0275 0.0275
Onchocerca volvulus 0.0068 0.0152 0.0195
Loa Loa (eye worm) steroid hormone receptor 0.011 0.0275 0.0355
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Mycobacterium tuberculosis Cadmium inducible protein CadI 0.0045 0.0087 0.0465
Echinococcus granulosus cathepsin l1 0.0034 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.005
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.011 0.0275 0.0275
Brugia malayi Steroid receptor seven-up type 2 0.011 0.0275 0.0355
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0002 0.0002
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0121 0.0592
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0077 0.0411
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0184 0.0486 0.0627
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0017 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0017
Loa Loa (eye worm) hypoxia-induced factor 1 0.0151 0.0393 0.0506
Schistosoma mansoni organic anion transporter 0.0028 0.0039 0.0039
Leishmania major glucose transporter, lmgt1 0.0015 0.0001 0.0003
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0068 0.0152 0.0152
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0073 0.0166 0.0818
Plasmodium vivax glyoxalase I, putative 0.0193 0.0513 0.4972
Echinococcus granulosus cathepsin l1 0.0051 0.0104 0.0104
Brugia malayi hypothetical protein 0.0164 0.0429 0.0553
Schistosoma mansoni cell polarity protein 0.0479 0.1334 0.1334
Schistosoma mansoni notch 0.0479 0.1334 0.1334
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.01 0.0128
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0056 0.0072
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0037 0.0064 0.0337
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0028 0.0275
Echinococcus multilocularis epidermal growth factor receptor 0.0081 0.0189 0.0189
Schistosoma mansoni netrin receptor unc5 0.0015 0.0002 0.0002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0007 0.0039
Echinococcus multilocularis lipoxygenase domain containing protein 0.0141 0.0362 0.0362
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.011 0.0275 0.0275
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.009 0.0482
Echinococcus multilocularis G-protein coupled receptor, putative 0.0068 0.0152 0.0152
Schistosoma mansoni transcription factor LCR-F1 0.0078 0.0181 0.0181
Echinococcus multilocularis methionine synthase reductase 0.0017 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0104 0.0509
Schistosoma mansoni survival motor neuron protein 0.0095 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0095 0.0232 0.0299
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0001 0.0001
Onchocerca volvulus 0.0068 0.0152 0.0195
Brugia malayi EGF-like domain containing protein 0.0479 0.1334 0.1721
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0002 0.0002
Echinococcus multilocularis epidermal growth factor receptor 0.015 0.0388 0.0388
Leishmania major glucose transporter, lmgt3 0.0015 0.0001 0.0003
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.01 0.0534
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0033 0.0322
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0007 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0513 0.275
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0013 0.0094
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.003 0.0145
Echinococcus multilocularis pyruvate kinase 0.0018 0.001 0.001
Onchocerca volvulus 0.0068 0.0152 0.0195
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0081 0.0189 0.0189
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.028 0.1504
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0037 0.0064 0.0341
Plasmodium vivax vivapain-3 0.0026 0.0033 0.0316
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0073 0.0166 0.0215
Mycobacterium ulcerans short chain dehydrogenase 0.0045 0.0086 0.046
Echinococcus multilocularis microtubule associated protein 2 0.3498 1 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0052 0.0108 0.0108
Brugia malayi orphan nuclear receptor NR2E1 0.0052 0.0108 0.0139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0056 0.0272
Echinococcus granulosus tm gpcr rhodopsin 0.0068 0.0152 0.0152
Echinococcus granulosus lipoxygenase domain containing protein 0.0141 0.0362 0.0362
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0037 0.0064 0.0341
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0121 0.0647
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0069 0.0368
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0121 0.0647
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.011 0.0275 0.0275
Brugia malayi FAD binding domain containing protein 0.0017 0.0006 0.0008
Echinococcus granulosus peroxidasin 0.2716 0.7755 0.7755
Schistosoma mansoni hypothetical protein 0.0251 0.0679 0.0679
Plasmodium falciparum pyruvate kinase 2 0.0018 0.001 0.009
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Echinococcus granulosus lysine specific demethylase 5A 0.0063 0.0138 0.0138
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0112 0.028 0.521
Echinococcus granulosus solute carrier family 22 0.0015 0.0001 0.0001
Echinococcus granulosus histone deacetylase 0.0134 0.0343 0.0343
Brugia malayi Nuclear hormone receptor family member nhr-1 0.011 0.0275 0.0355
Schistosoma mansoni adenoreceptor 0.0068 0.0152 0.0152
Brugia malayi jmjC domain containing protein 0.0016 0.0003 0.0005
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0037 0.0064 0.0337
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0037 0.0064 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0513 0.275
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0121 0.0647
Echinococcus granulosus cysteine protease 0.0026 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Brugia malayi hypothetical protein 0.0058 0.0126 0.0162
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0104 0.0509
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.003 0.0145
Brugia malayi hypothetical protein 0.0016 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Brugia malayi Inositol-1 0.0038 0.0069 0.0088
Plasmodium falciparum thioredoxin reductase 0.0049 0.01 0.0959
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0128 0.0128
Trichomonas vaginalis aldo-keto reductase, putative 0.0184 0.0486 0.2394
Loa Loa (eye worm) hypothetical protein 0.0092 0.0222 0.0287
Schistosoma mansoni neuropeptide f receptor 76f 0.0068 0.0152 0.0152
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0007 0.0064
Echinococcus multilocularis solute carrier family 22 0.0015 0.0001 0.0001
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.0059 0.0437
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0073 0.0166 0.0166
Brugia malayi CHD4 protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) animal heme peroxidase 0.2716 0.7755 1
Echinococcus granulosus g protein coupled receptor 0.0068 0.0152 0.0152
Trypanosoma brucei unspecified product 0.0035 0.0058 0.0309
Loa Loa (eye worm) hypothetical protein 0.0307 0.084 0.1084
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0068 0.0152 0.0152
Schistosoma mansoni fatty acid binding protein 0.0035 0.0058 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0028 0.0136
Leishmania major cytochrome p450-like protein 0.0037 0.0064 0.0341
Loa Loa (eye worm) hypothetical protein 0.0051 0.0104 0.0134
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Brugia malayi EGF-like domain containing protein 0.0479 0.1334 0.1721
Loa Loa (eye worm) hypothetical protein 0.0051 0.0106 0.0136
Schistosoma mansoni growth hormone secretagogue receptor 0.0068 0.0152 0.0152
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0077 0.0411
Loa Loa (eye worm) animal heme peroxidase 0.2716 0.7755 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Brugia malayi Doublecortin family protein 0.0141 0.0362 0.0467
Echinococcus granulosus death domain containing protein 0.0015 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.008 0.0769
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0059 0.0076
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0028 0.0039 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0842 0.2375 0.2375
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0037 0.0064 0.0341
Onchocerca volvulus 0.006 0.013 0.0167
Onchocerca volvulus 0.0103 0.0255 0.0328
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.0316 0.1697
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0048 0.0097 0.0723
Onchocerca volvulus Protein ultraspiracle homolog 0.011 0.0275 0.0354
Onchocerca volvulus 0.0045 0.0086 0.011
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0037 0.0064 0.0337
Entamoeba histolytica hypothetical protein 0.0078 0.0181 0.1759
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0068 0.0152 0.0152
Echinococcus multilocularis fat cadherin tumor suppressor 0.0479 0.1334 0.1334
Echinococcus multilocularis expressed protein 0.0019 0.0013 0.0013
Plasmodium vivax glyoxalase I, putative 0.0045 0.0087 0.0834
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0077 0.0408
Brugia malayi Uncoordinated protein 44 0.0015 0.0002 0.0002
Echinococcus multilocularis histone deacetylase 3 0.0374 0.1032 0.1032
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0021 0.0027
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0001 0.0001
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0104 0.0133
Schistosoma mansoni zinc finger protein 0.0052 0.0108 0.0108
Echinococcus multilocularis fatty acid binding protein FABP2 0.0035 0.0058 0.0058
Echinococcus granulosus cathepsin L cysteine protease 0.0026 0.0033 0.0033
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0058 0.0126 0.0126
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0013 0.0017
Loa Loa (eye worm) doublecortin family protein 0.0141 0.0362 0.0467
Schistosoma mansoni inositol monophosphatase 0.0038 0.0069 0.0069
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0037 0.0064 0.0341
Schistosoma mansoni hypothetical protein 0.0479 0.1334 0.1334
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Leishmania major myo-inositol/proton symporter (MIT) 0.0015 0.0001 0.0003
Schistosoma mansoni opsin-like receptor 0.0068 0.0152 0.0152
Brugia malayi hypothetical protein 0.2716 0.7755 1
Schistosoma mansoni histone deacetylase 4 5 0.0134 0.0343 0.0343
Echinococcus multilocularis follistatin 0.0019 0.0013 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0055 0.0267
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0108 0.0108
Brugia malayi Blistered cuticle protein 3 0.2716 0.7755 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.005
Loa Loa (eye worm) hypothetical protein 0.0109 0.027 0.0348
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Onchocerca volvulus 0.0051 0.0104 0.0133
Loa Loa (eye worm) G-protein coupled receptor 0.0068 0.0152 0.0196
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Echinococcus multilocularis voltage gated potassium channel subunit 0.0073 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0141 0.0362 0.0467
Echinococcus multilocularis peroxidasin 0.2716 0.7755 0.7755
Schistosoma mansoni alpha-1 adrenergic receptor 0.0068 0.0152 0.0152
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0012 0.0056
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0003
Echinococcus multilocularis aldehyde reductase 0.0111 0.0278 0.0278
Brugia malayi hypothetical protein 0.0078 0.0181 0.0234
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.01 0.0959
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0048 0.0257
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0021 0.0021
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0664 0.1865 1
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Onchocerca volvulus 0.0184 0.0486 0.0626
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0033 0.0178
Echinococcus granulosus slit 2 protein 0.0479 0.1334 0.1334
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0013 0.0094
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0664 0.1865 1
Brugia malayi G-protein coupled receptor 0.0068 0.0152 0.0196
Schistosoma mansoni hypothetical protein 0.0097 0.0237 0.0237
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.007 0.0519
Brugia malayi Delta serrate ligand family protein 0.0479 0.1334 0.1721
Loa Loa (eye worm) hypothetical protein 0.2716 0.7755 1
Plasmodium vivax plasmepsin IV, putative 0.0059 0.0128 0.1231
Trypanosoma cruzi aldo-keto reductase 0.0184 0.0486 0.2606
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0003 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0077 0.0411
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0069 0.051
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0037 0.0064 0.0341
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0184 0.0486 0.0486
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0042 0.0206
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0007 0.0039
Onchocerca volvulus 0.0184 0.0486 0.0626
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0037 0.0064 0.0337
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0007 0.0064
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0007 0.0039
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0138 0.0178
Schistosoma mansoni steroid hormone receptor ad4bp 0.011 0.0275 0.0275
Brugia malayi Histone deacetylase family protein 0.0134 0.0343 0.0442
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0037 0.0064 0.0337
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0251 0.0679 0.0679
Schistosoma mansoni potassium channel beta 0.0073 0.0166 0.0166
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.037 0.73
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.0152 0.0152
Schistosoma mansoni inositol monophosphatase 0.0038 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Echinococcus granulosus GPCR family 2 0.0097 0.0237 0.0237
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0097 0.0935
Trypanosoma brucei histone deacetylase 3 0.0134 0.0343 0.184
Toxoplasma gondii EGF family domain-containing protein 0.0479 0.1334 1
Echinococcus granulosus follistatin 0.0019 0.0013 0.0013
Brugia malayi jmjC domain containing protein 0.0016 0.0003 0.0005
Onchocerca volvulus 0.0028 0.0039 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0028 0.0136
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0121 0.1164
Brugia malayi Tachykinin-like peptides receptor 99D 0.0068 0.0152 0.0196
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0002 0.0009
Trypanosoma cruzi cruzipain precursor, putative 0.0017 0.0006 0.0034
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0027 0.0035 0.0035
Onchocerca volvulus 0.0034 0.0056 0.0071
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0144
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0099 0.0099
Mycobacterium ulcerans biphenyl-2,3-diol 1,2-dioxygenase 0.0045 0.0087 0.0462
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0007 0.0032
Loa Loa (eye worm) hypothetical protein 0.011 0.0275 0.0355
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0039
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0069 0.0368
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0077 0.0411
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.0152 0.0152
Brugia malayi Nuclear hormone receptor E75 0.0052 0.0108 0.0139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0068 0.0152 0.0152
Brugia malayi NADH-dependent xylose reductase 0.0073 0.0166 0.0215
Schistosoma mansoni peroxidasin 0.2716 0.7755 0.7755
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0088 0.043
Loa Loa (eye worm) hypothetical protein 0.0024 0.0028 0.0037
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0052 0.0108 0.0108
Echinococcus multilocularis g-protein coupled receptor 0.0068 0.0152 0.0152
Trypanosoma brucei glucose transporter, putative 0.0015 0.0001 0.0003
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0013 0.0017
Schistosoma mansoni coup transcription factor 0.011 0.0275 0.0275
Plasmodium falciparum histone deacetylase 1 0.0374 0.1032 1
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0033 0.0322
Schistosoma mansoni lipoxygenase 0.0588 0.1647 0.1647
Loa Loa (eye worm) TYRA-2 protein 0.0068 0.0152 0.0196
Brugia malayi hypothetical protein 0.0025 0.0031 0.004
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0664 0.1865 1
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0012 0.0056
Echinococcus multilocularis fibropellin Ia 0.0479 0.1334 0.1334
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Loa Loa (eye worm) neuropeptide F receptor 0.0068 0.0152 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0005
Trichomonas vaginalis aldo/keto reductase, putative 0.0184 0.0486 0.2394
Echinococcus multilocularis pyruvate kinase 0.0035 0.0059 0.0059
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0037 0.0064 0.0341
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Schistosoma mansoni rab6-interacting 0.0141 0.0362 0.0362
Onchocerca volvulus 0.0068 0.0152 0.0195
Loa Loa (eye worm) hypothetical protein 0.0164 0.0429 0.0553
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.0072
Schistosoma mansoni peroxidasin 0.2716 0.7755 0.7755
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) sugar transporter 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0068 0.0152 0.0196
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0027 0.0035 0.019
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0184 0.0486 0.0486
Plasmodium falciparum glyoxalase I 0.0045 0.0087 0.0834
Schistosoma mansoni notch 0.0479 0.1334 0.1334
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.01 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0104 0.0509
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0068 0.0152 0.0152
Schistosoma mansoni notch 0.0479 0.1334 0.1334
Onchocerca volvulus Peroxidasin homolog 0.2716 0.7755 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0061 0.03
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Trichomonas vaginalis aldo-keto reductase, putative 0.0184 0.0486 0.2394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0028 0.0136
Loa Loa (eye worm) TK/INSR protein kinase 0.0048 0.0096 0.0123
Echinococcus granulosus serotonin receptor 0.0068 0.0152 0.0152
Brugia malayi Cytochrome P450 family protein 0.0046 0.009 0.0116
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.008 0.0391
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0479 0.1334 0.1334
Echinococcus multilocularis neurogenic locus notch protein 4 0.0479 0.1334 0.1334
Brugia malayi histone deacetylase 1 (HD1) 0.0374 0.1032 0.1331
Trypanosoma brucei glucose transporter, putative 0.0015 0.0001 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.011 0.0275 0.0355
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0008
Onchocerca volvulus Putative cubilin 0.0479 0.1334 0.172
Entamoeba histolytica cysteine proteinase 1, putative 0.0026 0.0033 0.0322
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.0139
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0184 0.0486 0.0486
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0037 0.0064 0.0337
Entamoeba histolytica histone deacetylase, putative 0.0374 0.1032 1
Onchocerca volvulus 0.0068 0.0152 0.0195
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0077 0.0411
Echinococcus granulosus methionine synthase reductase 0.0017 0.0006 0.0006
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0121 0.0121
Brugia malayi latrophilin 2 splice variant baaae 0.021 0.0561 0.0724
Leishmania major cysteine peptidase A (CPA) 0.0051 0.0104 0.0557
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0073 0.0166 0.0892
Schistosoma mansoni cpg binding protein 0.0063 0.014 0.014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0045 0.0086 0.0111
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0001 0.0001
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0007 0.0039
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0003 0.0028
Schistosoma mansoni single-minded 0.0049 0.0099 0.0099
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0037 0.0064 0.0337
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0069 0.5663
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0001 0.0001
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0069 0.0365
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0479 0.1334 0.1721
Trichomonas vaginalis aldo-keto reductase, putative 0.0184 0.0486 0.2394
Brugia malayi Death domain containing protein 0.0015 0.0002 0.0002
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0068 0.0152 0.0152
Schistosoma mansoni opsin-like receptor 0.0068 0.0152 0.0152
Brugia malayi putative neuropeptide receptor NPR1 0.0068 0.0152 0.0196
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0068 0.0152 0.0152
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0097 0.0237 0.0237
Brugia malayi hypothetical protein 0.0015 0.0001 0.0001

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.3 nM Inhibition of renin ChEMBL. 21381769

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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