Detailed information for compound 34143

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 416.986 | Formula: C27H29ClN2
  • H donors: 1 H acceptors: 0 LogP: 6.02 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccccc1CN[C@H]1C2CCN([C@H]1C(c1ccccc1)c1ccccc1)CC2
  • InChi: 1S/C27H29ClN2/c28-24-14-8-7-13-23(24)19-29-26-22-15-17-30(18-16-22)27(26)25(20-9-3-1-4-10-20)21-11-5-2-6-12-21/h1-14,22,25-27,29H,15-19H2/t26-,27-/m0/s1
  • InChiKey: LURXNRSWKKLLDE-SVBPBHIXSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens tachykinin receptor 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K04224 tachykinin receptor 3, putative Get druggable targets OG5_137770 All targets in OG5_137770
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.005 0.0022 0.0266
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0104 0.0965
Entamoeba histolytica hypothetical protein 0.0068 0.0034 0.0424
Echinococcus granulosus 7tm_1 domain containing protein 0.0126 0.0072 0.0071
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0126 0.0072 0.0071
Echinococcus granulosus neuropeptides capa receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.1139 0.0729 0.9737
Schistosoma mansoni ran 0.0091 0.0049 0.0453
Schistosoma mansoni cpg binding protein 0.0117 0.0066 0.0609
Schistosoma mansoni hypothetical protein 0.0094 0.0051 0.0468
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0044 0.0018 0.0427
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0019 0.0002 0.0028
Loa Loa (eye worm) CXXC zinc finger family protein 0.0109 0.006 0.056
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0283 0.0174 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0015 0.3713
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Trichomonas vaginalis D-aminoacylase, putative 0.0101 0.0055 0.0711
Echinococcus granulosus replication factor c subunit 1 0.0019 0.0002 0.0001
Schistosoma mansoni rab6-interacting 0.0022 0.0004 0.0029
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.117 0.0749 1
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.0216 0.2861
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0026 0.0007 0.0006
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.005 0.0022 0.0201
Schistosoma mansoni myosin xvIII 0.0126 0.0072 0.0664
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Trypanosoma brucei target of rapamycin kinase 3, putative 0.116 0.0743 0.9919
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0283 0.0174 0.0173
Schistosoma mansoni peptidase Clp (S14 family) 0.0073 0.0037 0.0343
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0017 0.0197
Echinococcus multilocularis replication factor c subunit 1 0.0019 0.0002 0.0001
Plasmodium falciparum transportin 0.0029 0.0009 0.0478
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Brugia malayi hypothetical protein 0.0034 0.0012 0.0143
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0629 0.0398 0.5304
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0174 0.2305
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0743 0.0472 0.6288
Trichomonas vaginalis PIKK family atypical protein kinase 0.1139 0.0729 0.9737
Trypanosoma brucei polo-like protein kinase 0.0176 0.0104 0.1368
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0046 0.0591
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Echinococcus multilocularis snurportin 1 0.1663 0.1069 0.1069
Brugia malayi Associated with TFs and helicases family protein 0.0025 0.0006 0.0063
Echinococcus granulosus zinc finger protein 0.003 0.0009 0.0008
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0015 0.0175
Plasmodium vivax heterochromatin protein 1, putative 0.0025 0.0006 0.0331
Trypanosoma cruzi polo-like protein kinase, putative 0.0176 0.0104 0.0294
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0001 0.0004
Trichomonas vaginalis ran, putative 0.0091 0.0049 0.0628
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0126 0.0072 0.0071
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0024 0.1372
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0174 0.0495
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0084 0.0044 0.1999
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Onchocerca volvulus Huntingtin homolog 0.0178 0.0105 0.6531
Trichomonas vaginalis glutaminase, putative 0.0293 0.018 0.2377
Echinococcus granulosus neuropeptide receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Schistosoma mansoni hypothetical protein 0.049 0.0308 0.2875
Trichomonas vaginalis conserved hypothetical protein 0.049 0.0308 0.4094
Entamoeba histolytica hypothetical protein 0.0232 0.014 0.1846
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) ICD-1 protein 0.0022 0.0004 0.0034
Leishmania major hypothetical protein, conserved 0.0029 0.0009 0.002
Onchocerca volvulus 0.0126 0.0072 0.4394
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Onchocerca volvulus 0.0022 0.0004 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0418 0.0261 0.3464
Echinococcus multilocularis importin 5 0.0029 0.0009 0.0008
Echinococcus granulosus serine protein kinase ATM 0.0664 0.0421 0.042
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0008 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0026 0.0007 0.0073
Brugia malayi topoisomerase 0.0019 0.0002 0.0013
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0007 0.0057
Loa Loa (eye worm) beta-lactamase 0.0101 0.0055 0.0512
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.031 0.0191 0.467
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0101 0.0055 0.0511
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni hypothetical protein 0.0126 0.0072 0.0664
Brugia malayi phosphofructokinase 0.0119 0.0067 0.0868
Brugia malayi RE15519p 0.0126 0.0072 0.0925
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0649 0.0411 0.1177
Schistosoma mansoni intermediate filament proteins 0.0135 0.0077 0.0715
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0126 0.0072 0.0925
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Mycobacterium tuberculosis Conserved protein 0.0101 0.0055 0.1341
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.0026 0.0025
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0126 0.0072 0.0664
Trichomonas vaginalis PIKK family atypical protein kinase 0.0232 0.014 0.1846
Onchocerca volvulus 0.0126 0.0072 0.4394
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Onchocerca volvulus 0.0126 0.0072 0.4394
Brugia malayi hypothetical protein 0.0178 0.0105 0.1369
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.014 0.1302
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0126 0.0072 0.0071
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0073 0.0037 0.0502
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0044 0.0018 0.0971
Schistosoma mansoni hypothetical protein 0.0094 0.0051 0.0468
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0067 0.0881
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Giardia lamblia NADH oxidase lateral transfer candidate 0.0047 0.002 0.0243
Chlamydia trachomatis endonuclease IV 0.0084 0.0044 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Mycobacterium ulcerans beta-lactamase 0.0101 0.0055 0.3052
Onchocerca volvulus 0.0101 0.0055 0.3358
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0019 0.0169
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0126 0.0072 0.0071
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0015 0.0171
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0064
Loa Loa (eye worm) hypothetical protein 0.0094 0.0051 0.0468
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Loa Loa (eye worm) hypothetical protein 0.0075 0.0038 0.0354
Loa Loa (eye worm) importin-beta domain-containing protein 0.0029 0.0009 0.0077
Trichomonas vaginalis glutathione reductase, putative 0.0047 0.002 0.0243
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Echinococcus granulosus neuropeptide FF receptor 2 0.0126 0.0072 0.0071
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0044 0.0018 0.0971
Brugia malayi RNA binding protein 0.0223 0.0135 0.1755
Mycobacterium tuberculosis Putative ferredoxin reductase 0.031 0.0191 0.467
Brugia malayi Cytochrome P450 family protein 0.0071 0.0036 0.0453
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0156 0.0091 0.0845
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.031 0.0191 0.467
Loa Loa (eye worm) hypothetical protein 0.0448 0.028 0.2618
Loa Loa (eye worm) PHD-finger family protein 0.0048 0.002 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0722 0.0458 0.6106
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0021 0.0251
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.003
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0025 0.0006 0.032
Onchocerca volvulus 0.0232 0.014 0.872
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0006 0.0313
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0051 0.0023 0.031
Brugia malayi RNA recognition motif domain containing protein 0.0223 0.0135 0.1755
Toxoplasma gondii PHD-finger domain-containing protein 0.0048 0.002 0.0276
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0052
Loa Loa (eye worm) hypothetical protein 0.0032 0.0011 0.0095
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.0026 0.0355
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.0067 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0022 0.0004 0.009
Echinococcus granulosus neutral alpha glucosidase AB 0.0051 0.0023 0.0022
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0026 0.0007 0.0058
Toxoplasma gondii NAC domain-containing protein 0.0022 0.0004 0.0056
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0044 0.0018 0.0427
Loa Loa (eye worm) hypothetical protein 0.0072 0.0036 0.0337
Trypanosoma brucei trypanothione reductase 0.0136 0.0078 0.1024
Onchocerca volvulus Neuropeptide F receptor homolog 0.0126 0.0072 0.4394
Echinococcus granulosus G protein coupled receptor 139 0.0126 0.0072 0.0071
Schistosoma mansoni ap endonuclease 0.0039 0.0015 0.0136
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0015 0.0184
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0664 0.0421 0.3932
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Brugia malayi cytoplasmic intermediate filament protein 0.0072 0.0036 0.0464
Trypanosoma cruzi FHA domain containing protein, putative 0.0019 0.0002 0.0002
Echinococcus multilocularis 0.0232 0.014 0.0139
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0024 0.1372
Loa Loa (eye worm) phosphatidylinositol 3 0.0117 0.0065 0.0608
Leishmania major basic transcription factor 3a, putative 0.0022 0.0004 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0004 0.0205
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0101 0.0055 0.0512
Leishmania major phosphatidylinositol 3-kinase, putative 0.1139 0.0729 0.2004
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus dro:myosuppressin receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Loa Loa (eye worm) G-protein coupled receptor 0.0126 0.0072 0.0665
Echinococcus multilocularis serotonin receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.049 0.0308 0.0307
Leishmania major phosphatidylinositol 3-related kinase, putative 0.115 0.0737 0.2023
Echinococcus granulosus Chromo domain 0.0025 0.0006 0.0005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0232 0.014 0.342
Brugia malayi Melatonin receptor type 1A 0.0126 0.0072 0.0925
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0026 0.0007 0.0073
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0004 0.0003
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0021 0.0281
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0019 0.0002 0.0013
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0448 0.028 0.0279
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0073 0.0037 0.0036
Brugia malayi neuropeptide F receptor 0.0126 0.0072 0.0925
Echinococcus granulosus cpg binding protein 0.0117 0.0066 0.0065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0026 0.0007 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0044 0.0018 0.0427
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Plasmodium falciparum glutathione reductase 0.0136 0.0078 0.447
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Leishmania major hypothetical protein, conserved 0.0053 0.0024 0.0063
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0015 0.0845
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.117 0.0749 0.2058
Loa Loa (eye worm) neuropeptide F receptor 0.0126 0.0072 0.0665
Echinococcus multilocularis neuropeptides capa receptor 0.0126 0.0072 0.0071
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.0398
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0044 0.0018 0.0971
Onchocerca volvulus 0.0101 0.0055 0.3358
Echinococcus granulosus intermediate filament protein 0.0135 0.0077 0.0076
Echinococcus granulosus neuropeptide receptor A26 0.0423 0.0264 0.0263
Entamoeba histolytica hypothetical protein 0.0664 0.0421 0.5606
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus importin 5 0.0029 0.0009 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0004 0.0205
Trichomonas vaginalis set domain proteins, putative 0.0263 0.016 0.2117
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0026 0.0325
Schistosoma mansoni hypothetical protein 0.0094 0.0051 0.0468
Brugia malayi MAP kinase sur-1 0.0057 0.0026 0.0331
Loa Loa (eye worm) RecQ helicase 0.0024 0.0005 0.0044
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0022 0.0058
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Brugia malayi jmjC domain containing protein 0.0156 0.0091 0.1177
Trypanosoma cruzi major cysteine proteinase, putative 0.0039 0.0015 0.0038
Toxoplasma gondii FATC domain-containing protein 0.0664 0.0421 0.5675
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0232 0.014 0.1824
Echinococcus granulosus biogenic amine 5HT receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0014 0.0166
Echinococcus granulosus chromobox protein 1 0.0089 0.0047 0.0047
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0006 0.0331
Mycobacterium leprae Probable lipase LipE 0.0101 0.0055 0.2512
Echinococcus multilocularis g-protein coupled receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0033 0.0011 0.001
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0073 0.0037 0.2136
Echinococcus granulosus nibrin 0.0019 0.0002 0.0001
Leishmania major cathepsin L-like protease 0.0049 0.0022 0.0056
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Brugia malayi nuclear receptor NHR-88 0.0026 0.0007 0.0073
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0026 0.0072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0034
Brugia malayi beta-lactamase family protein 0.0101 0.0055 0.071
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0348 0.0216 0.2861
Brugia malayi FAT domain containing protein 0.049 0.0308 0.4029
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0283 0.0174 0.0173
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0283 0.0174 0.162
Echinococcus multilocularis serotonin receptor 0.0126 0.0072 0.0071
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0174 0.0474
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0044 0.0018 0.0427
Echinococcus multilocularis peptidase Clp (S14 family) 0.0048 0.0021 0.002
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0025 0.0006 0.0063
Mycobacterium tuberculosis Conserved protein 0.0101 0.0055 0.1341
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0113 0.0063 0.0062
Echinococcus granulosus jumonji domain containing protein 0.0066 0.0033 0.0032
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0099 0.0054 0.0498
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0176 0.0104 0.0103
Brugia malayi M-phase phosphoprotein, mpp8 0.0124 0.007 0.0905
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0348 0.0216 0.0616
Loa Loa (eye worm) cytochrome P450 family protein 0.0071 0.0036 0.0329
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0126 0.0072 0.0664
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0185 0.011 0.6818
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0232 0.014 0.0139
Trichomonas vaginalis mercuric reductase, putative 0.0047 0.002 0.0243
Mycobacterium ulcerans epimerase 0.0022 0.0004 0.0197
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.005 0.0022 0.0201
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0002 0.0002
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0232 0.014 0.8057
Toxoplasma gondii hypothetical protein 0.0025 0.0006 0.0081
Schistosoma mansoni neuropeptide F-like receptor 0.0126 0.0072 0.0664
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0108 0.1004
Brugia malayi Bromodomain containing protein 0.0087 0.0046 0.0587
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0108 0.1003
Echinococcus granulosus somatostatin receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0349 0.0216 0.2016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Brugia malayi Calcitonin receptor-like protein seb-1 0.0297 0.0182 0.2378
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0041 0.0016 0.0201
Leishmania major hypothetical protein, conserved 0.5614 0.3635 1
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0029 0.0009 0.0099
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Onchocerca volvulus Bile acid receptor homolog 0.0026 0.0007 0.029
Trypanosoma brucei transcription factor BTF3, putative 0.0022 0.0004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0073 0.0037 0.0344
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0047 0.002 0.0019
Brugia malayi Serotonin receptor 0.0126 0.0072 0.0925
Schistosoma mansoni jumonji domain containing protein 0.0124 0.007 0.0649
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0007 0.0073
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0026 0.0007 0.0057
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0101 0.0055 0.3052
Brugia malayi Serotonin receptor 0.0126 0.0072 0.0925
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0433 0.027 0.0773
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.5396
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0026 0.0007 0.0057
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0044 0.2531
Schistosoma mansoni alpha-glucosidase 0.0199 0.0119 0.111
Trichomonas vaginalis PIKK family atypical protein kinase 0.1139 0.0729 0.9737
Loa Loa (eye worm) hypothetical protein 0.0135 0.0077 0.0716
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0126 0.0072 0.0665
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0067 0.0872
Echinococcus multilocularis ecdysone induced protein 78C 0.0026 0.0007 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Schistosoma mansoni steroid hormone receptor ad4bp 0.0026 0.0007 0.0057
Entamoeba histolytica hypothetical protein 0.0068 0.0034 0.0424
Echinococcus multilocularis g protein coupled receptor 0.0126 0.0072 0.0071
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Onchocerca volvulus 0.0034 0.0011 0.0595
Onchocerca volvulus Alhambra homolog 0.0048 0.002 0.1165
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0067 0.0624
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0026 0.0007 0.0073
Brugia malayi Probable ClpP-like protease 0.0073 0.0037 0.0474
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0062 0.003 0.0278
Onchocerca volvulus Huntingtin homolog 0.0178 0.0105 0.6531
Echinococcus granulosus histone acetyltransferase KAT2B 0.0151 0.0088 0.0087
Schistosoma mansoni lipoxygenase 0.0022 0.0004 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0664 0.0421 0.5606
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0021 0.0251
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0005 0.0053
Schistosoma mansoni hypothetical protein 0.0044 0.0018 0.0162
Loa Loa (eye worm) hypothetical protein 0.0124 0.007 0.0651
Loa Loa (eye worm) melatonin receptor type 1A 0.0126 0.0072 0.0665
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0005 0.0042
Brugia malayi photoreceptor-specific nuclear receptor 0.0026 0.0007 0.0073
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0283 0.0174 0.2266
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0047 0.002 0.0052
Loa Loa (eye worm) hypothetical protein 0.0045 0.0019 0.0174
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0348 0.0216 0.2861
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0042
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3846 0.2487 0.2487
Loa Loa (eye worm) hypothetical protein 0.0121 0.0068 0.0631
Schistosoma mansoni hypothetical protein 0.0025 0.0006 0.005
Echinococcus multilocularis neuropeptide s receptor 0.0423 0.0264 0.0263
Brugia malayi AKH receptor 0.0126 0.0072 0.0925
Onchocerca volvulus 0.0109 0.006 0.3684
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0002 0.0013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Echinococcus granulosus alpha 1A adrenergic receptor 0.0126 0.0072 0.0071
Plasmodium vivax basic transcription factor 3b, putative 0.0022 0.0004 0.0231
Toxoplasma gondii cytochrome p450 superfamily protein 0.0044 0.0018 0.0241
Schistosoma mansoni hypothetical protein 0.0094 0.0051 0.0468
Trichomonas vaginalis PIKK family atypical protein kinase 0.066 0.0418 0.5571
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0047 0.002 0.0251
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0348 0.0216 0.2861
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0629 0.0398 0.5304
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0232 0.014 0.0139
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0126 0.0072 0.0664
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0008 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Schistosoma mansoni hypothetical protein 0.0232 0.014 0.1304
Brugia malayi PHD-finger family protein 0.0024 0.0005 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0026 0.0007 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.117 0.0749 1
Schistosoma mansoni chromosome transmission fidelity factor 0.0019 0.0002 0.0014
Schistosoma mansoni transcription factor btf3 0.0022 0.0004 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0047 0.0608
Toxoplasma gondii target of rapamycin (TOR), putative 0.1158 0.0742 1
Brugia malayi beta-lactamase 0.0101 0.0055 0.071
Echinococcus granulosus orexin receptor type 2 0.0126 0.0072 0.0071
Leishmania major phosphatidylinositol 3-kinase, putative 0.0283 0.0174 0.0474
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0101 0.0055 0.0155
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0047 0.002 0.0252
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0047 0.002 0.5162
Onchocerca volvulus 0.0126 0.0072 0.4394
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0004 0.0123
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0126 0.0072 0.4394
Echinococcus granulosus transcription factor btf3 0.0022 0.0004 0.0003
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0035 0.0012 0.0011
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0126 0.0072 0.0665
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0032 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus granulosus thioredoxin glutathione reductase 0.0136 0.0078 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0026 0.0316
Echinococcus granulosus GTP binding nuclear protein Ran 0.0091 0.0049 0.0048
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus translational activator gcn1 0.0029 0.0009 0.0008
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.005 0.0022 0.0201
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0004 0.0205
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0047 0.002 0.1101
Trichomonas vaginalis PIKK family atypical protein kinase 0.1151 0.0737 0.9838
Echinococcus granulosus cytochrome P450 2K1 0.0044 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0099 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0124 0.007 0.0651
Schistosoma mansoni loxhd1 0.0022 0.0004 0.0029
Echinococcus granulosus microtubule associated protein 2 0.0596 0.0377 0.0376
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0009 0.0118
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0232 0.014 0.1304
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0629 0.0398 0.5304
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0067 0.0872
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.119 0.0763 0.2185
Schistosoma mansoni lamin 0.0135 0.0077 0.0715
Schistosoma mansoni retinoic acid receptor RXR 0.0026 0.0007 0.0057
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0004 0.0098
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0126 0.0072 0.0931
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0016 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.117 0.0749 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0026 0.0007 0.0073
Plasmodium vivax importin-beta 2, putative 0.0156 0.0091 0.5222
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus bloom syndrome protein 0.0024 0.0005 0.0004
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0283 0.0174 0.2297
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0126 0.0072 0.0664
Entamoeba histolytica hypothetical protein 0.0068 0.0034 0.0424
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0004 0.0003
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.0067 0.0066
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0038 0.0354
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0011 0.0583
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.066 0.0418 0.5571
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Trypanosoma cruzi transcription factor btf3, putative 0.0022 0.0004 0.0008
Brugia malayi hypothetical protein 0.0019 0.0002 0.0013
Onchocerca volvulus 0.0101 0.0055 0.3358
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0044 0.0018 0.0971
Brugia malayi Cytochrome P450 family protein 0.0121 0.0068 0.0878
Brugia malayi beta-NAC-like protein 0.0022 0.0004 0.004
Schistosoma mansoni smad1 5 8 and 0.0018 0.0001 0.0005
Onchocerca volvulus 0.0064 0.0031 0.1823
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0026 0.0241
Onchocerca volvulus 0.0022 0.0004 0.0103
Echinococcus granulosus importin subunit beta 1 0.0156 0.0091 0.009
Plasmodium falciparum glutathione reductase 0.0047 0.002 0.1139
Mycobacterium ulcerans lipase LipD 0.0101 0.0055 0.3052
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0232 0.014 0.1824
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0055 0.0026 0.149
Schistosoma mansoni hypothetical protein 0.0021 0.0003 0.0026
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0664 0.0421 0.561
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0047 0.002 0.0019
Toxoplasma gondii PHD-finger domain-containing protein 0.0048 0.002 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0 0.0019
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Brugia malayi Valyl-tRNA synthetase 0.0025 0.0006 0.0063
Plasmodium falciparum heterochromatin protein 1 0.0025 0.0006 0.0313
Mycobacterium leprae conserved hypothetical protein 0.0101 0.0055 0.2512
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0108 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Entamoeba histolytica Ran family GTPase 0.0091 0.0049 0.0628
Schistosoma mansoni biogenic amine receptor 0.0126 0.0072 0.0664
Loa Loa (eye worm) hypothetical protein 0.0132 0.0075 0.0701
Schistosoma mansoni opsin-like receptor 0.0126 0.0072 0.0664
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0629 0.0398 0.114
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0024 0.0005 0.0004
Mycobacterium tuberculosis Probable esterase LipL 0.0101 0.0055 0.1341
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0009 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.117 0.0749 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0032 0.0298
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.0024 0.0023
Echinococcus granulosus g-protein coupled receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0126 0.0072 0.0071
Onchocerca volvulus 0.0126 0.0072 0.4394
Schistosoma mansoni bromodomain containing protein 0.0075 0.0038 0.0351
Trichomonas vaginalis hypothetical protein 0.0029 0.0009 0.009
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0011 0.2304
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0044 0.0018 0.0971
Onchocerca volvulus 0.0126 0.0072 0.4394
Trypanosoma cruzi cytochrome P450, putative 0.0071 0.0036 0.0098
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0024 0.1389
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0045 0.0019 0.005
Schistosoma mansoni topbp1 0.0019 0.0002 0.0014
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0091 0.0049 0.066
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0345 0.0213 0.5221
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0126 0.0072 0.0071
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0047 0.0608
Echinococcus granulosus sex peptide receptor 0.0126 0.0072 0.0071
Schistosoma mansoni hypothetical protein 0.1663 0.1069 1
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0044 0.0018 0.0971
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0113 0.0063 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.0026 0.0072
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0465 0.0292 0.3877
Schistosoma mansoni neuropeptide F-like receptor 0.0126 0.0072 0.0664
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0126 0.0072 0.0071
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Entamoeba histolytica hypothetical protein 0.0025 0.0006 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Brugia malayi Dopamine receptor protein 1 0.0126 0.0072 0.0925
Trichomonas vaginalis hypothetical protein 0.0025 0.0006 0.0051
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0047 0.002 0.1139
Loa Loa (eye worm) hypothetical protein 0.0034 0.0011 0.0103
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0024 0.0066
Onchocerca volvulus 0.0126 0.0072 0.4394
Mycobacterium tuberculosis Probable hydrolase 0.0101 0.0055 0.1341
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0126 0.0072 0.0071
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0175 0.0103 0.1339
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0146 0.1927
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0108 0.0107
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0126 0.0072 0.0071
Echinococcus multilocularis neuropeptides capa receptor 0.0126 0.0072 0.0071
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0126 0.0072 0.0664
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Brugia malayi PHD-finger family protein 0.0048 0.002 0.0254
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0297 0.0182 0.17
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0021 0.0281
Entamoeba histolytica hypothetical protein 0.0025 0.0006 0.0051
Brugia malayi kap beta 3 protein 0.0029 0.0009 0.01
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0041 0.0016 0.0149
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0047 0.002 0.1101
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0026 0.0007 0.0006
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0047 0.002 0.0484
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Brugia malayi F/Y-rich N-terminus family protein 0.0052 0.0023 0.0292
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0067 0.0872
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0073 0.0037 0.0036
Brugia malayi hypothetical protein 0.0124 0.007 0.0905
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0094 0.0051 0.005
Schistosoma mansoni cytochrome P450 0.0044 0.0018 0.0162
Loa Loa (eye worm) thioredoxin reductase 0.0136 0.0078 0.0724
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0024 0.0327
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0006 0.005
Loa Loa (eye worm) phosphatidylinositol 3 0.0232 0.014 0.1305
Toxoplasma gondii endonuclease IV APN 0.0084 0.0044 0.0597
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0383 0.0238 0.3161
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Echinococcus granulosus g protein coupled receptor 0.0126 0.0072 0.0071
Brugia malayi Cytochrome P450 family protein 0.0071 0.0036 0.0453
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.1854
Leishmania major cathepsin L-like protease 0.0049 0.0022 0.0056
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0158 0.0092 0.0091
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0044 0.0018 0.0427
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Loa Loa (eye worm) glutaminase 2 0.0293 0.018 0.1676
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0048 0.0021 0.0499
Loa Loa (eye worm) G-protein coupled receptor 0.0126 0.0072 0.0665
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0091 0.0049 0.2799
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0345 0.0213 1
Schistosoma mansoni alpha glucosidase 0.0051 0.0023 0.021
Echinococcus multilocularis FTZ F1 alpha 0.0026 0.0007 0.0006
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0061 0.0029 0.0028
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0004 0.004
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus multilocularis dro:myosuppressin receptor 0.0126 0.0072 0.0071
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0052
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0232 0.014 0.1306
Trypanosoma cruzi cytochrome P450, putative 0.0071 0.0036 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0009 0.0098
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0232 0.014 0.1308
Onchocerca volvulus 0.0126 0.0072 0.4394
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.053 0.0334 0.444
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Echinococcus granulosus lamin dm0 0.0135 0.0077 0.0076
Brugia malayi 6-phosphofructokinase 0.0119 0.0067 0.0868
Echinococcus multilocularis g protein coupled receptor 0.0126 0.0072 0.0071
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.205
Plasmodium vivax thioredoxin reductase, putative 0.0136 0.0078 0.448
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.0067 0.0066
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Loa Loa (eye worm) hypothetical protein 0.0048 0.002 0.0187
Echinococcus granulosus Chromobox protein 3 0.0025 0.0006 0.0005
Trypanosoma brucei importin beta-1 subunit, putative 0.0156 0.0091 0.1196
Entamoeba histolytica protein kinase rad3, putative 0.0649 0.0411 0.5477
Trichomonas vaginalis importin beta-1, putative 0.0126 0.0072 0.0931
Onchocerca volvulus 0.0126 0.0072 0.4394
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0047 0.002 0.0052
Schistosoma mansoni opsin-like receptor 0.0126 0.0072 0.0664
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0126 0.0072 0.0925
Echinococcus granulosus tachykinin peptides receptor 99D 0.0126 0.0072 0.0071
Trichomonas vaginalis sucrase-isomaltase, putative 0.0051 0.0023 0.0281
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0176 0.0104 0.0103
Loa Loa (eye worm) hypothetical protein 0.0053 0.0024 0.0222
Mycobacterium ulcerans endonuclease IV 0.0084 0.0044 0.2447
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0176 0.0104 0.0965
Echinococcus granulosus FTZ F1 alpha 0.0026 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.005 0.0022 0.0274
Trichomonas vaginalis PIKK family atypical protein kinase 0.1151 0.0737 0.9838
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Loa Loa (eye worm) hypothetical protein 0.0433 0.027 0.2526
Toxoplasma gondii melibiase subfamily protein 0.0113 0.0063 0.0846
Leishmania major cytochrome p450-like protein 0.0071 0.0036 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0026 0.0007 0.0058
Loa Loa (eye worm) cytochrome P450 0.0044 0.0018 0.0163
Onchocerca volvulus 0.0126 0.0072 0.4394
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.0026 0.0242
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0005 0.0004
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0001 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) Smad1 0.0018 0.0001 0.0006
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0063 0.0582
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0176 0.0104 0.0282
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0025 0.0006 0.0079
Echinococcus granulosus hypothetical protein 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0054 0.0024 0.0224
Onchocerca volvulus 0.0134 0.0077 0.4717
Leishmania major hypothetical protein, unknown function 0.0232 0.014 0.0381
Echinococcus multilocularis thioredoxin glutathione reductase 0.0136 0.0078 0.0077
Echinococcus multilocularis importin subunit beta 1 0.0156 0.0091 0.009
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0015 0.0184
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0006 0.0051
Toxoplasma gondii ABC1 family protein 0.0101 0.0055 0.0744
Schistosoma mansoni kinase 0.009 0.0048 0.0442
Brugia malayi hypothetical protein 0.0068 0.0034 0.0429
Echinococcus granulosus neuropeptide Y receptor 0.0126 0.0072 0.0071
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.119 0.0763 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0232 0.014 0.1305
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0044 0.0018 0.0427
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Loa Loa (eye worm) hypothetical protein 0.0178 0.0105 0.0981
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0044 0.0018 0.0427
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0011 0.0142
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.031 0.0191 0.467
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0091 0.0049 0.0137
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.0398
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0047 0.002 0.0184
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0015 0.0137
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Brugia malayi N-terminal motif family protein 0.0185 0.011 0.1428
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Schistosoma mansoni chromobox protein 0.0025 0.0006 0.005
Echinococcus granulosus GPCR family 2 0.0094 0.0051 0.005
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0019 0.0002 0.0002
Schistosoma mansoni neuropeptide f receptor 76f 0.0126 0.0072 0.0664
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.0023 0.0062
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0044 0.0018 0.0971
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Leishmania major phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.0381
Echinococcus granulosus fmrfamide receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis neuropeptide receptor 0.0126 0.0072 0.0071
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1139 0.0729 0.9737
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0005 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0026 0.0325
Schistosoma mansoni lipoxygenase 0.0061 0.0029 0.0266
Schistosoma mansoni chromobox protein 0.0025 0.0006 0.005
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0126 0.0072 0.0071
Brugia malayi hypothetical protein 0.0022 0.0004 0.0034
Brugia malayi G protein-coupled receptor 0.0126 0.0072 0.0925
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0113 0.0063 0.0062
Loa Loa (eye worm) acetyltransferase 0.0158 0.0092 0.0856
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0047 0.002 0.0054
Loa Loa (eye worm) phosphatidylinositol 3 0.0232 0.014 0.1305
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0067 0.0872
Onchocerca volvulus 0.0026 0.0007 0.029
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0001 0.0005
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0223 0.0135 0.1256
Schistosoma mansoni hypothetical protein 0.0203 0.0121 0.1129
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0044 0.0018 0.0971
Onchocerca volvulus 0.0019 0.0002 0.0001
Schistosoma mansoni biogenic amine (5HT) receptor 0.0126 0.0072 0.0664
Echinococcus granulosus chromobox protein 1 0.0089 0.0047 0.0047
Brugia malayi follicle stimulating hormone receptor 0.0561 0.0354 0.4633
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0804 0.0512 0.0511
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0629 0.0398 0.114
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Loa Loa (eye worm) phosphatidylinositol 3 0.0739 0.047 0.439
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0028 0.0344
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.117 0.0749 0.2147
Onchocerca volvulus 0.0263 0.016 1
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0019 0.0002 0.0089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.117 0.0749 1
Echinococcus multilocularis geminin 0.035 0.0217 0.0216
Echinococcus granulosus 7TM GPCR rhodopsin 0.0126 0.0072 0.0071
Brugia malayi larval opioid receptor 0.0126 0.0072 0.0925
Echinococcus multilocularis neuropeptide receptor A26 0.0423 0.0264 0.0263
Echinococcus multilocularis microtubule associated protein 2 0.0596 0.0377 0.0376
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0044 0.0018 0.0164
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.0067 0.3081
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0099 0.0054 0.0053
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0013 0.0013
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0009 0.0008
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.8057
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0044 0.0018 0.0047
Echinococcus granulosus tumor protein p63 0.0434 0.0272 0.0271
Echinococcus multilocularis chromobox protein 2 0.0025 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Brugia malayi Glycosyl hydrolases family 31 protein 0.0232 0.014 0.1826
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0091 0.0049 0.0628
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Echinococcus multilocularis musashi 0.0135 0.0077 0.0076
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0004 0.004
Schistosoma mansoni fkbp-rapamycin associated protein 0.0649 0.0411 0.3842
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0019 0.0169
Loa Loa (eye worm) glutaminase 0.0293 0.018 0.1676
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0007 0.0073
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Brugia malayi Bromodomain containing protein 0.0054 0.0025 0.0307
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0026 0.0007 0.0073
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0232 0.014 0.0139
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.119 0.0763 0.0762
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0012 0.0168
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0059 0.0028 0.1624
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0063 0.0582
Trypanosoma brucei protein kinase, putative 0.0057 0.0026 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Brugia malayi jmjC domain containing protein 0.0066 0.0032 0.0409
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0007 0.0057
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0035 0.0012 0.0144
Loa Loa (eye worm) hypothetical protein 0.0084 0.0044 0.041
Brugia malayi hypothetical protein 0.0134 0.0076 0.099
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0091 0.0049 0.0048
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0006 0.0079
Toxoplasma gondii histone lysine methyltransferase SET1 0.0214 0.0128 0.1731
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0068 0.0034 0.0033
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0011 0.0601
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0004 0.0028
Onchocerca volvulus 0.0124 0.007 0.4298
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0804 0.0512 0.4783
Echinococcus granulosus serotonin receptor 0.0126 0.0072 0.0071
Giardia lamblia Phosphatidylinositol 4-kinase 0.0232 0.014 0.1846
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0126 0.0072 0.0664
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0051 0.0023 0.0281
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.0026 0.0069
Echinococcus granulosus dnaJ subfamily B 0.0316 0.0195 0.0194
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0071 0.0036 0.0035
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0024 0.0217
Plasmodium vivax hypothetical protein, conserved 0.0048 0.002 0.1172
Plasmodium vivax hypothetical protein 0.0232 0.014 0.8057
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0094 0.0051 0.005
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0026 0.0007 0.0006
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0019 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0044 0.0018 0.0427
Loa Loa (eye worm) transcription factor SMAD2 0.026 0.0158 0.1477
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0044 0.0018 0.0047
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0024 0.0005 0.0004
Loa Loa (eye worm) phosphatidylinositol 3 0.0232 0.014 0.1305
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0283 0.0174 0.2297
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0232 0.014 0.1846
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0101 0.0055 0.1341
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0044 0.0018 0.0971
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0126 0.0072 0.0925
Brugia malayi G protein-coupled receptor F59B2.13 0.0126 0.0072 0.0925
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.2121
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.8057
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0026 0.0325
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus multilocularis beta LACTamase domain containing family member 0.0101 0.0055 0.0054
Loa Loa (eye worm) phosphatidylinositol 3 0.117 0.0749 0.7004
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0232 0.014 0.0139
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0007 0.0057
Echinococcus multilocularis Zinc finger, PHD finger 0.0283 0.0174 0.0173
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Schistosoma mansoni neuropeptide receptor 0.0126 0.0072 0.0664
Schistosoma mansoni hypothetical protein 0.0316 0.0195 0.1815
Echinococcus granulosus tm gpcr rhodopsin 0.0126 0.0072 0.0071
Schistosoma mansoni hypothetical protein 0.035 0.0217 0.2024
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0034
Schistosoma mansoni histamine h1 receptor 0.0126 0.0072 0.0664
Onchocerca volvulus 0.0135 0.0077 0.4738
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0015 0.0014
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0032 0.0297
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0017 0.0197
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0011 0.0142
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0033
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0005 0.0042
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.117 0.0749 0.0748
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0047 0.002 0.0054
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0232 0.014 0.1854
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0026 0.0007 0.0073
Mycobacterium tuberculosis Probable lipase LipE 0.0101 0.0055 0.1341
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0004 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0044 0.0018 0.0427
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Schistosoma mansoni ran 0.0091 0.0049 0.0453
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0025 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0022 0.0058
Echinococcus multilocularis serine protein kinase ATM 0.0664 0.0421 0.042
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0021 0.002
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.005 0.0022 0.0267
Loa Loa (eye worm) neuropeptide F receptor 0.0126 0.0072 0.0665
Schistosoma mansoni hypothetical protein 0.0126 0.0072 0.0664
Onchocerca volvulus 0.0126 0.0072 0.4394
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0011 0.1307
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0048 0.0021 0.0499
Loa Loa (eye worm) steroid hormone receptor 0.0026 0.0007 0.0058
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.0067 0.3723
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.117 0.0749 0.7003
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0044 0.0018 0.0427
Mycobacterium ulcerans esterase/lipase LipP 0.0101 0.0055 0.3052
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0022 0.0004 0.0205
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Entamoeba histolytica acyl-CoA synthetase, putative 0.0022 0.0004 0.0028
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0047 0.002 0.0272
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0232 0.014 0.0398
Brugia malayi steroid hormone receptor 0.0026 0.0007 0.0073
Toxoplasma gondii exonuclease III APE 0.0039 0.0015 0.0204
Trichomonas vaginalis PIKK family atypical protein kinase 0.068 0.0431 0.574
Toxoplasma gondii HEAT repeat-containing protein 0.0156 0.0091 0.1224
Trichomonas vaginalis esterase, putative 0.0101 0.0055 0.0711
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0001 0.0021
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0044 0.0018 0.0971
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0035 0.0012 0.0011
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0044 0.0018 0.0427
Brugia malayi cytochrome P450 0.0044 0.0018 0.022
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni hypothetical protein 0.0126 0.0072 0.0664
Entamoeba histolytica acyl-CoA synthetase, putative 0.0022 0.0004 0.0028
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0006 0.0051
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.8378
Loa Loa (eye worm) hypothetical protein 0.0065 0.0032 0.0293
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0158 0.0092 0.0855
Echinococcus multilocularis g protein coupled receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0126 0.0072 0.0071
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0044 0.0018 0.0427
Echinococcus granulosus PHD finger protein rhinoceros 0.0048 0.002 0.002
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0001 0.005
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0561 0.0354 0.3306
Plasmodium vivax sentrin-specific protease 1, putative 0.005 0.0022 0.126
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0044 0.0018 0.0221
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0007 0.0057
Entamoeba histolytica hypothetical protein 0.0022 0.0004 0.0028
Onchocerca volvulus 0.0022 0.0004 0.0103
Brugia malayi Glycosyl hydrolases family 31 protein 0.0051 0.0023 0.0288
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0044 0.0018 0.0427
Loa Loa (eye worm) CHromoDomain protein family member 0.0033 0.0011 0.01
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0232 0.014 0.1846
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.0026 0.0025
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0026 0.0007 0.0006
Echinococcus multilocularis lamin dm0 0.0135 0.0077 0.0076
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0073 0.0037 0.0502
Trypanosoma cruzi hypothetical protein, conserved 0.5383 0.3485 1
Plasmodium falciparum thioredoxin reductase 0.0136 0.0078 0.447
Echinococcus multilocularis neuropeptide receptor 0.0126 0.0072 0.0071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0002 0.0002
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.116 0.0743 0.2041
Trichomonas vaginalis conserved hypothetical protein 0.0418 0.0261 0.3464
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0091 0.0049 0.0637
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0345 0.0213 0.5221
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.0026 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0668 0.0423 0.5638
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0094 0.0051 0.005
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0283 0.0174 0.0173
Schistosoma mansoni neuropeptide receptor 0.0126 0.0072 0.0664
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0026 0.0007 0.0058
Echinococcus granulosus chromobox protein 2 0.0025 0.0006 0.0005
Entamoeba histolytica hypothetical protein 0.0232 0.014 0.1846
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.002 0.0054
Brugia malayi Glycosyl hydrolases family 31 protein 0.0019 0.0002 0.0012
Treponema pallidum NADH oxidase 0.0047 0.002 0.2786
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0044 0.2546
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Entamoeba histolytica transcription factor BTF3, putative 0.0022 0.0004 0.0028
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0283 0.0174 0.162
Chlamydia trachomatis DNA ligase 0.0019 0.0002 0.0363
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.117 0.0749 0.2058
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0004 0.0205
Echinococcus granulosus geminin 0.035 0.0217 0.0216
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0047 0.002 0.0252
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0664 0.0421 0.1204
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0015 0.0359
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0398 0.0248 0.3292
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0232 0.014 0.1824
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0044 0.0018 0.0971
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0063 0.0582
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.0024 0.0023
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0283 0.0174 0.2297
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.117 0.0749 0.0748
Onchocerca volvulus 0.0126 0.0072 0.4394
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.115 0.0737 0.9832
Brugia malayi isocitrate dehydrogenase 0.0018 0.0001 0.0003
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0048 0.002 0.0187
Schistosoma mansoni hypothetical protein 0.035 0.0217 0.2024
Toxoplasma gondii ATPase, AAA family protein 0.0019 0.0002 0.0028
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0026 0.0007 0.0058
Mycobacterium tuberculosis Conserved protein 0.0101 0.0055 0.1341
Schistosoma mansoni neuropeptide receptor 0.0126 0.0072 0.0664
Echinococcus multilocularis neuropeptide FF receptor 2 0.0126 0.0072 0.0071
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0448 0.028 0.0279
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0232 0.014 0.8054
Loa Loa (eye worm) hypothetical protein 0.0039 0.0015 0.0136
Echinococcus multilocularis somatostatin receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) phosphatidylinositol 3 0.115 0.0737 0.6886
Schistosoma mansoni growth hormone secretagogue receptor 0.0126 0.0072 0.0664
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0004 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0067 0.0872
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0048 0.0021 0.0887
Brugia malayi glutaminase DH11.1 0.0293 0.018 0.2345
Schistosoma mansoni adenoreceptor 0.0126 0.0072 0.0664
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0136 0.0078 0.1898
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0015 0.004
Brugia malayi hypothetical protein 0.0053 0.0024 0.0304
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0044 0.0018 0.0971
Loa Loa (eye worm) cytochrome P450 family protein 0.0071 0.0036 0.0329
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.001 0.0009
Entamoeba histolytica acyl-coA synthetase, putative 0.0022 0.0004 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0044 0.0018 0.0427
Echinococcus multilocularis dnaJ subfamily B 0.0316 0.0195 0.0194
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0047 0.002 0.1101
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0126 0.0072 0.0071
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.119 0.0763 0.7129
Echinococcus granulosus neuropeptide Y receptor 0.0126 0.0072 0.0071
Mycobacterium tuberculosis Probable dehydrogenase 0.031 0.0191 0.467
Trypanosoma cruzi polo-like protein kinase, putative 0.0176 0.0104 0.0294
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0051 0.0023 0.0211
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0002 0.0002
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0015 0.0817
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0101 0.0055 0.0511
Brugia malayi serine/threonine-protein kinase plk-2 0.0176 0.0104 0.1347
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0025 0.0006 0.0005
Trypanosoma cruzi trypanothione reductase, putative 0.0136 0.0078 0.022
Brugia malayi putative neuropeptide receptor 0.0126 0.0072 0.0925
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.205
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0126 0.0072 0.0664
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.117 0.0749 1
Onchocerca volvulus 0.0126 0.0072 0.4394
Echinococcus multilocularis 0.0044 0.0018 0.0017
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1663 0.1069 1
Giardia lamblia Kinase, PLK 0.0176 0.0104 0.136
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0004 0.0003
Echinococcus multilocularis nibrin 0.0019 0.0002 0.0001
Brugia malayi latrophilin 2 splice variant baaae 0.0203 0.0121 0.1578
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0296 0.0182 0.2409
Schistosoma mansoni cellular tumor antigen P53 0.0064 0.0031 0.0284
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.049 0.0308 0.0307
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0156 0.0091 0.009
Trichomonas vaginalis penicillin-binding protein, putative 0.0101 0.0055 0.0711
Trichomonas vaginalis PIKK family atypical protein kinase 0.0668 0.0423 0.5638
Schistosoma mansoni DNA ligase IV 0.0019 0.0002 0.0014
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0024 0.0306
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0047 0.002 0.1156
Echinococcus multilocularis zinc finger protein 0.003 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.1139 0.0729 0.9737
Schistosoma mansoni biogenic amine receptor 0.0126 0.0072 0.0664
Loa Loa (eye worm) hypothetical protein 0.0649 0.0411 0.3842
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0007 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0029 0.0264
Mycobacterium leprae putative cytochrome p450 0.0044 0.0018 0.0748
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0065 0.0032 0.0031
Brugia malayi Doublecortin family protein 0.0022 0.0004 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Giardia lamblia PHD finger protein 15 0.0048 0.002 0.0247
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0026 0.0007 0.0057
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0246 0.015 0.0426
Schistosoma mansoni opsin-like receptor 0.0126 0.0072 0.0664
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0629 0.0398 0.5304
Brugia malayi ORL1-like opioid receptor 0.0126 0.0072 0.0925
Echinococcus multilocularis transcription factor btf3 0.0022 0.0004 0.0003
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0038 0.0354
Loa Loa (eye worm) heterochromatin protein 1 0.0089 0.0047 0.044
Echinococcus multilocularis PHD finger protein rhinoceros 0.0048 0.002 0.002
Echinococcus multilocularis G protein coupled receptor 139 0.0126 0.0072 0.0071
Schistosoma mansoni rab6-interacting 0.0022 0.0004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0071 0.0036 0.0035
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0001 0.0004
Echinococcus granulosus tar DNA binding protein 0.0223 0.0135 0.0134
Schistosoma mansoni importin-beta 2 0.0029 0.0009 0.0077
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0005 0.0004
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0022 0.0004 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Brugia malayi Dopamine receptor 0.0126 0.0072 0.0925
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0101 0.0055 0.1341
Brugia malayi acetyltransferase, GNAT family protein 0.0158 0.0092 0.1193
Leishmania major cytochrome p450-like protein 0.0044 0.0018 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0026 0.0007 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.031 0.0191 0.8937
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0044 0.0018 0.0427
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0084 0.0044 0.1075
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0011 0.0583
Plasmodium vivax SET domain protein, putative 0.0035 0.0012 0.071
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Loa Loa (eye worm) TAR-binding protein 0.0223 0.0135 0.1256
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0348 0.0216 0.2014
Echinococcus multilocularis neuropeptide Y receptor 0.0126 0.0072 0.0071
Brugia malayi Pre-SET motif family protein 0.0231 0.014 0.182
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Brugia malayi PHD-finger family protein 0.0035 0.0013 0.0151
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0126 0.0072 0.0664
Echinococcus granulosus peptide allatostatin:somatostatin 0.0126 0.0072 0.0071
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0026 0.0007 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0022 0.0058
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0068 0.0034 0.0033
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0046 0.0591
Plasmodium vivax glutathione reductase, putative 0.0136 0.0078 0.448
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Onchocerca volvulus Serine\/threonine kinase homolog 0.0176 0.0104 0.6424
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0044 0.0018 0.0971
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0032 0.0297
Schistosoma mansoni RAR-like nuclear receptor 0.0026 0.0007 0.0057
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Brugia malayi Tachykinin-like peptides receptor 99D 0.0126 0.0072 0.0925
Leishmania major phosphatidylinositol kinase related protein, putative 0.0246 0.015 0.0408
Loa Loa (eye worm) hypothetical protein 0.0203 0.0121 0.113
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0047 0.002 0.1139
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0649 0.0411 0.041
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0126 0.0072 0.0925
Brugia malayi nuclear hormone receptor 0.0026 0.0007 0.0073
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0126 0.0072 0.0071
Mycobacterium ulcerans hypothetical protein 0.0101 0.0055 0.3052
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0044 0.0018 0.0427
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0024 0.0217
Brugia malayi CXXC zinc finger family protein 0.0109 0.006 0.0778
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0156 0.0091 0.009
Onchocerca volvulus 0.0126 0.0072 0.4394
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Onchocerca volvulus 0.0126 0.0072 0.4394
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Plasmodium vivax transportin, putative 0.0029 0.0009 0.0496
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0094 0.0051 0.0649
Plasmodium vivax replication factor C subunit 1, putative 0.0019 0.0002 0.0111
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0126 0.0072 0.0665
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.025 0.0152 0.2015
Trichomonas vaginalis helicase, putative 0.0025 0.0006 0.0048
Echinococcus multilocularis jumonji domain containing protein 0.0066 0.0033 0.0032
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0645 0.0408 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0009 0.0075
Echinococcus granulosus peregrin 0.0054 0.0025 0.0024
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0108 0.1401
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0015 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.0023 0.0062
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.0067 0.0181
Schistosoma mansoni microtubule-associated protein tau 0.0596 0.0377 0.3518
Schistosoma mansoni transcription factor LCR-F1 0.0068 0.0034 0.0311
Trichomonas vaginalis D-aminoacylase, putative 0.0101 0.0055 0.0711
Brugia malayi G-protein coupled receptor 0.0126 0.0072 0.0925
Echinococcus granulosus transportin 1 0.0029 0.0009 0.0008
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0448 0.028 0.3667
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0283 0.0174 0.162
Echinococcus granulosus g protein coupled receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0015 0.0175
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0067 0.0624
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0011 0.0114
Loa Loa (eye worm) kap beta 3 protein 0.0029 0.0009 0.0077
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0006 0.0331
Echinococcus multilocularis neutral alpha glucosidase AB 0.0051 0.0023 0.0022
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0047 0.002 0.0252
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0044 0.0018 0.0971
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0013 0.0151
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0067 0.0872
Loa Loa (eye worm) helicase 0.0025 0.0006 0.0051
Echinococcus granulosus neuropeptides capa receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0053 0.0024 0.0218
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0232 0.014 0.1304
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0091 0.0049 0.0453
Toxoplasma gondii NADPH-glutathione reductase 0.0047 0.002 0.0272
Onchocerca volvulus 0.0124 0.007 0.4298
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0649 0.0411 0.5386
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0075 0.0038 0.0486
Echinococcus granulosus ecdysone induced protein 78C 0.0026 0.0007 0.0006
Brugia malayi G-protein coupled receptor 0.0126 0.0072 0.0925
Loa Loa (eye worm) phosphofructokinase 0.0119 0.0067 0.0624
Mycobacterium leprae conserved hypothetical protein 0.0232 0.014 0.6524
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0091 0.0049 0.2812
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0026 0.0007 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0232 0.014 0.1846
Trichomonas vaginalis PIKK family atypical protein kinase 0.067 0.0425 0.5659
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0028 0.0344
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0007 0.0006
Leishmania major hypothetical protein, conserved 0.0101 0.0055 0.0148
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0015 0.0171
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0026 0.0007 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0044 0.0018 0.0427
Trypanosoma cruzi hypothetical protein, conserved 0.0101 0.0055 0.0155
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0084 0.0044 0.0567
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0011 0.2304
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0026 0.0007 0.029
Brugia malayi chromobox protein homolog 3 0.0055 0.0026 0.0322
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0004 0.004
Leishmania major cytochrome p450-like protein 0.0044 0.0018 0.0046
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0101 0.0055 0.071
Plasmodium falciparum thioredoxin reductase 0.0047 0.002 0.1139
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0044 0.0018 0.0427
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0026 0.0007 0.0057
Echinococcus multilocularis GPCR, family 2 0.0094 0.0051 0.005
Echinococcus multilocularis Chromo domain 0.0025 0.0006 0.0005
Brugia malayi Steroid receptor seven-up type 2 0.0026 0.0007 0.0073
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0004 0.0008
Schistosoma mansoni hypothetical protein 0.0048 0.002 0.0187
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) hypothetical protein 0.0185 0.011 0.1024
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0283 0.0174 0.2342
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus granulosus neuropeptide receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0004 0.0031
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0044 0.0018 0.0046
Onchocerca volvulus 0.0135 0.0077 0.4738
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.0026 0.0069
Brugia malayi glutathione reductase 0.0136 0.0078 0.1008
Entamoeba histolytica hypothetical protein 0.0068 0.0034 0.0424
Echinococcus multilocularis orexin receptor type 2 0.0126 0.0072 0.0071
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0044 0.0018 0.0427
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0297 0.0182 0.2378
Schistosoma mansoni cpg binding protein 0.0117 0.0066 0.0609
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0003 0.0163
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0283 0.0174 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0126 0.0072 0.0664
Plasmodium falciparum replication factor C subunit 1, putative 0.0019 0.0002 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Brugia malayi intermediate filament protein 0.0135 0.0077 0.0997
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0015 0.2003
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Toxoplasma gondii thioredoxin reductase 0.0136 0.0078 0.105
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0031 0.0009 0.0108
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0044 0.0018 0.0971
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0022 0.0004 0.0205
Leishmania major phosphatidylinositol kinase, putative 0.0232 0.014 0.0381
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0174 0.0495
Trypanosoma cruzi cruzipain precursor, putative 0.0049 0.0022 0.0058
Schistosoma mansoni hypothetical protein 0.0024 0.0005 0.0043
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Schistosoma mansoni hypothetical protein 0.0068 0.0034 0.0311
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0004 0.0028
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0047 0.002 0.4501
Echinococcus multilocularis transportin 1 0.0029 0.0009 0.0008
Echinococcus multilocularis fmrfamide receptor 0.0126 0.0072 0.0071
Brugia malayi Latrophilin receptor protein 2 0.0094 0.0051 0.0649
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0006 0.005
Brugia malayi hypothetical protein 0.0022 0.0004 0.0034
Entamoeba histolytica hypothetical protein 0.0232 0.014 0.1846
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0026 0.0007 0.0058
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0021 0.1191
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0044 0.0018 0.0971
Plasmodium falciparum importin beta, putative 0.0156 0.0091 0.5213
Echinococcus multilocularis sex peptide receptor 0.0126 0.0072 0.0071
Schistosoma mansoni biogenic amine (5HT) receptor 0.0126 0.0072 0.0664
Brugia malayi Protein cec-1. 0.0025 0.0006 0.0063
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0232 0.014 0.1887
Brugia malayi CHD4 protein 0.0033 0.0011 0.0132
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0025 0.0006 0.0313
Schistosoma mansoni alpha-glucosidase 0.0199 0.0119 0.111
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0804 0.0512 0.0511
Brugia malayi GnHR receptor homolog 0.0126 0.0072 0.0925
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0025 0.0006 0.0338
Brugia malayi Intermediate filament tail domain containing protein 0.0135 0.0077 0.0997
Plasmodium vivax hypothetical protein, conserved 0.0232 0.014 0.8057
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0026 0.0316
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.8378
Entamoeba histolytica HEAT repeat domain containing protein 0.0029 0.0009 0.009
Entamoeba histolytica hypothetical protein 0.0025 0.0006 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0014 0.0166
Echinococcus granulosus beta LACTamase domain containing family member 0.0101 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0024 0.0066
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0025 0.0006 0.0187
Mycobacterium leprae Conserved hypothetical protein 0.0044 0.0018 0.0748
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0015 0.0863
Echinococcus granulosus g protein coupled receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0065 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0232 0.014 0.1305
Leishmania major glycosyl hydrolase-like protein 0.0019 0.0002 0.0002
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0006 0.005
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0004 0.0223
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0126 0.0072 0.0925
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0348 0.0216 0.2868
Schistosoma mansoni smad1 5 8 and 0.0018 0.0001 0.0005
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0033 0.0011 0.001
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0283 0.0174 0.2297
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0004 0.0197
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0047 0.002 0.0252
Echinococcus granulosus lysosomal alpha glucosidase 0.0232 0.014 0.0139
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.0216 0.2861
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Echinococcus granulosus peptidase Clp S14 family 0.0048 0.0021 0.002
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.5047 0.3267 0.3267
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0026 0.0007 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0004 0.0028
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0044 0.0018 0.0047
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Loa Loa (eye worm) hypothetical protein 0.0082 0.0043 0.0394
Brugia malayi RNA, U transporter 1 0.0443 0.0277 0.3627
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Echinococcus multilocularis peregrin 0.0054 0.0025 0.0024
Loa Loa (eye worm) RNA binding protein 0.0223 0.0135 0.1256
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.0026 0.0334
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.0026 0.0025
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0044 0.0018 0.0971
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0011 0.0114
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0004 0.003
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.053 0.0334 0.444
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0026 0.0007 0.0058
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.117 0.0749 0.9824
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0126 0.0072 0.0664
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0071 0.0036 0.1962
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Trypanosoma cruzi transcription factor btf3, putative 0.0022 0.0004 0.0008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0108 0.0107
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0072 0.0036 0.0336
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0033 0.0011 0.01
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0001 0.0069
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0015 0.0175
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0027 0.0026
Echinococcus multilocularis lysosomal alpha glucosidase 0.0232 0.014 0.0139
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0004 0.0087
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.117 0.0749 0.2147
Mycobacterium ulcerans glutaminase 0.0293 0.018 1
Brugia malayi Cytochrome P450 family protein 0.0044 0.0018 0.022
Trypanosoma brucei cytochrome P450, putative 0.0071 0.0036 0.0459
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0004 0.0003
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0025 0.0006 0.0606
Schistosoma mansoni ap endonuclease 0.0039 0.0015 0.0136
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0565 0.0356 0.4741
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0051 0.0023 0.0281
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0007 0.0073
Echinococcus multilocularis allatostatin A receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) TYRA-2 protein 0.0126 0.0072 0.0665
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0044 0.0018 0.0971
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Loa Loa (eye worm) latrophilin receptor protein 2 0.0094 0.0051 0.0468
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.0067 0.1635
Brugia malayi neuropeptide F receptor 0.0126 0.0072 0.0925
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0007 0.0006
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0001 0.0008
Brugia malayi TAR-binding protein 0.0223 0.0135 0.1755
Plasmodium falciparum sentrin-specific protease 1 0.005 0.0022 0.1243
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0004 0.0003
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0232 0.014 0.1304
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0126 0.0072 0.0664
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0117 0.0065 0.0184
Loa Loa (eye worm) hypothetical protein 0.0182 0.0108 0.1002
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 1.5416 1 1
Loa Loa (eye worm) MH2 domain-containing protein 0.026 0.0158 0.1477
Plasmodium falciparum phd finger protein, putative 0.0048 0.002 0.1156
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0099 0.0054 0.0498
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0108 0.0107
Trypanosoma brucei glucosidase, putative 0.0051 0.0023 0.029
Echinococcus granulosus tm gpcr rhodopsin 0.0126 0.0072 0.0071
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.119 0.0763 0.0762
Echinococcus multilocularis RUN 0.0022 0.0004 0.0003
Brugia malayi 6-phosphofructokinase 0.0119 0.0067 0.0868
Schistosoma mansoni Smad4 0.0018 0.0001 0.0005
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0004 0.0204
Onchocerca volvulus Protein ultraspiracle homolog 0.0026 0.0007 0.029
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0051 0.0023 0.0281
Echinococcus granulosus mixed lineage leukemia protein mll 0.0028 0.0008 0.0007
Echinococcus granulosus RUN 0.0022 0.0004 0.0003
Brugia malayi Heterochromatin protein 1 0.0089 0.0047 0.0609
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0061 0.0029 0.0028
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0091 0.0049 0.0137
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0722 0.0458 0.6179
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0009 0.0098
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0026 0.0072
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.005 0.0022 0.0267
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0232 0.014 0.0139
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0067 0.0624
Trypanosoma brucei glycosyl hydrolase-like protein 0.0019 0.0002 0.001
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma cruzi target of rapamycin kinase 3 0.116 0.0743 0.2129
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0035 0.0012 0.0144
Brugia malayi SET domain containing protein 0.0029 0.0008 0.0093
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0091 0.0049 0.0628
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0126 0.0072 0.0664
Schistosoma mansoni cpg binding protein 0.0109 0.006 0.0559
Mycobacterium ulcerans hypothetical protein 0.0022 0.0004 0.0205
Echinococcus multilocularis thyroid hormone receptor alpha 0.0026 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0062 0.003 0.0278
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0007 0.0073
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0015 0.004
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) cytochrome P450 family protein 0.0121 0.0068 0.0631
Brugia malayi putative neuropeptide receptor NPR1 0.0126 0.0072 0.0925
Giardia lamblia GTOR 0.117 0.0749 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0232 0.014 0.0139
Loa Loa (eye worm) phosphatidylinositol kinase 0.0232 0.014 0.1305
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0004 0.0186
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0047 0.002 0.5162
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0283 0.0174 0.2342
Loa Loa (eye worm) hypothetical protein 0.0064 0.0031 0.0284
Schistosoma mansoni neuropeptide receptor 0.0126 0.0072 0.0664
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0007 0.0073
Schistosoma mansoni zinc finger protein 0.003 0.0009 0.008
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0094 0.0051 0.005
Schistosoma mansoni hypothetical protein 0.0022 0.0004 0.0029
Schistosoma mansoni hypothetical protein 0.0126 0.0072 0.0664
Brugia malayi Pre-SET motif family protein 0.0035 0.0012 0.0149
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0001 0.0018
Schistosoma mansoni biogenic amine receptor 0.0126 0.0072 0.0664
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0067 0.0189
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Echinococcus granulosus biogenic amine 5HT receptor 0.0126 0.0072 0.0071
Plasmodium falciparum basic transcription factor 3b, putative 0.0022 0.0004 0.0213
Schistosoma mansoni coup transcription factor 0.0026 0.0007 0.0057
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0006 0.0051
Loa Loa (eye worm) jmjC domain-containing protein 0.0098 0.0053 0.0495
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0004 0.0092
Schistosoma mansoni smad1 5 8 and 0.0018 0.0001 0.0005
Brugia malayi sulfakinin receptor protein 0.0126 0.0072 0.0925
Trypanosoma brucei importin beta-1 subunit, putative 0.0156 0.0091 0.1196
Loa Loa (eye worm) glutathione reductase 0.0136 0.0078 0.0724
Echinococcus granulosus snurportin 1 0.1663 0.1069 0.1069
Echinococcus multilocularis chromobox protein 1 0.0089 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0034
Echinococcus multilocularis tar DNA binding protein 0.0223 0.0135 0.0134
Onchocerca volvulus 0.0126 0.0072 0.4394
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0283 0.0174 0.2297
Onchocerca volvulus 0.0126 0.0072 0.4394
Leishmania major trypanothione reductase 0.0136 0.0078 0.0211
Brugia malayi Bromodomain containing protein 0.0043 0.0017 0.0215
Leishmania major alpha glucosidase II subunit, putative 0.0051 0.0023 0.006
Schistosoma mansoni smad 0.0018 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus multilocularis neuropeptide Y receptor 0.0126 0.0072 0.0071
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.119 0.0763 0.2185
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0026 0.0325
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0011 0.0114
Echinococcus granulosus neuropeptide s receptor 0.0423 0.0264 0.0263
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0649 0.0411 0.5477
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0026 0.0007 0.0057
Echinococcus multilocularis G-protein coupled receptor, putative 0.0126 0.0072 0.0071
Echinococcus multilocularis lamin 0.0135 0.0077 0.0076
Mycobacterium ulcerans hypothetical protein 0.0022 0.0004 0.0197
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0011 0.0601
Echinococcus multilocularis sentrin specific protease 1 0.005 0.0022 0.0021
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0015 0.0014
Leishmania major cathepsin L-like protease 0.0049 0.0022 0.0056
Schistosoma mansoni chromobox protein 0.0089 0.0047 0.0439
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0011 0.0142
Schistosoma mansoni polycystin 1-related 0.0022 0.0004 0.0029
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0015 0.0175
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0004 0.0003
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0126 0.0072 0.0664
Leishmania major GTP-binding protein, putative 0.0091 0.0049 0.0131
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Echinococcus multilocularis tumor protein p63 0.0434 0.0272 0.0271
Schistosoma mansoni alpha-1 adrenergic receptor 0.0126 0.0072 0.0664
Onchocerca volvulus 0.006 0.0029 0.1687
Trypanosoma brucei hypothetical protein, conserved 0.0101 0.0055 0.072
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Trichomonas vaginalis penicillin-binding protein, putative 0.0101 0.0055 0.0711
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0731 0.0464 0.6191
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0002 0.001
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0067 0.0624
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Trypanosoma cruzi importin beta-1 subunit, putative 0.0126 0.0072 0.0202
Schistosoma mansoni lamin 0.0135 0.0077 0.0715
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0044 0.0018 0.0427
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0108 0.1003
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0232 0.014 0.0398
Echinococcus multilocularis Chromobox protein 3 0.0025 0.0006 0.0005
Trichomonas vaginalis Heterochromatin protein, putative 0.0025 0.0006 0.0051
Echinococcus multilocularis translational activator gcn1 0.0029 0.0009 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0007 0.0073
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0007 0.0073
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0007 0.0006
Giardia lamblia Hypothetical protein 0.0232 0.014 0.1846
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0649 0.0411 0.041
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.117 0.0749 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0022 0.0004 0.0205
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0044 0.0018 0.0971
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.0026 0.0325
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0067 0.0872
Trichomonas vaginalis D-aminoacylase, putative 0.0101 0.0055 0.0711
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0044 0.0018 0.0971
Loa Loa (eye worm) hypothetical protein 0.0055 0.0026 0.0235
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0003 0.0026
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0017 0.0942
Brugia malayi ecdysteroid receptor 0.0026 0.0007 0.0073
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0348 0.0216 0.2819
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.005 0.0022 0.0297
Loa Loa (eye worm) intermediate filament protein 0.0135 0.0077 0.0716
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0006 0.0079
Schistosoma mansoni chromobox protein 0.0089 0.0047 0.0439
Echinococcus granulosus allatostatin A receptor 0.0126 0.0072 0.0071
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0232 0.014 0.1887
Brugia malayi beta-lactamase family protein 0.0101 0.0055 0.071
Brugia malayi Thioredoxin reductase 0.0136 0.0078 0.1008
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0126 0.0072 0.0071
Schistosoma mansoni topbp1 0.0019 0.0002 0.0014
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0126 0.0072 0.0665
Plasmodium vivax hypothetical protein, conserved 0.0101 0.0055 0.3171
Brugia malayi hypothetical protein 0.0019 0.0002 0.0013
Mycobacterium tuberculosis Probable reductase 0.031 0.0191 0.467
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0028 0.0008 0.0007
Mycobacterium tuberculosis Probable oxidoreductase 0.0345 0.0213 0.5221
Loa Loa (eye worm) CYP4Cod1 0.0071 0.0036 0.0329
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Entamoeba histolytica hypothetical protein 0.0565 0.0356 0.4741
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Mycobacterium tuberculosis Probable lipase LipD 0.0101 0.0055 0.1341
Entamoeba histolytica hypothetical protein 0.0126 0.0072 0.0931
Trichomonas vaginalis maltase-glucoamylase, putative 0.0051 0.0023 0.0281
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Loa Loa (eye worm) hypothetical protein 0.0297 0.0182 0.17
Schistosoma mansoni importin beta-1 0.0156 0.0091 0.0844
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0135 0.0077 0.0716
Echinococcus multilocularis chromobox protein 1 0.0089 0.0047 0.0047
Loa Loa (eye worm) histone methyltransferase 0.0035 0.0012 0.011
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0101 0.0055 0.1341
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0232 0.014 0.1846
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0004 0.0038
Brugia malayi DKFZp564C0469 protein 0.0019 0.0002 0.0013
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0004 0.009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.005 0.0022 0.0266
Brugia malayi Melibiase family protein 0.0075 0.0038 0.0489
Brugia malayi Importin beta-1 subunit 0.0156 0.0091 0.1177
Loa Loa (eye worm) hypothetical protein 0.0178 0.0105 0.0981
Brugia malayi MH2 domain containing protein 0.026 0.0158 0.2065
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0664 0.0421 0.5512
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0629 0.0398 0.5217
Brugia malayi Pax transcription activation domain interacting protein 0.0019 0.0002 0.0013
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0001 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.115 0.0737 0.9832
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0073 0.0037 0.1662
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0668 0.0423 0.5638
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Echinococcus multilocularis fmrfamide receptor 0.0126 0.0072 0.0071
Echinococcus granulosus lamin 0.0135 0.0077 0.0076
Echinococcus granulosus tm gpcr rhodopsin 0.5047 0.3267 0.3267
Echinococcus granulosus sentrin specific protease 1 0.005 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) hypothetical protein 0.0722 0.0458 0.4282
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0108 0.1003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0012 0.0112
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0001 0.0006
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0051 0.0023 0.0281
Schistosoma mansoni glutaminase 0.0293 0.018 0.1676
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0126 0.0072 0.0931
Leishmania major importin beta-1 subunit, putative 0.0126 0.0072 0.0193
Entamoeba histolytica serine/threonine protein kinase, putative 0.0176 0.0104 0.136
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0047 0.002 0.1156
Echinococcus multilocularis cpg binding protein 0.0117 0.0066 0.0065
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0232 0.014 0.1887
Onchocerca volvulus 0.0232 0.014 0.872
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0232 0.014 0.8054
Loa Loa (eye worm) hypothetical protein 0.049 0.0308 0.2876
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0063 0.0582
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0006 0.0051
Brugia malayi Dopamine receptor protein 2 0.0126 0.0072 0.0925
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 7 mg kg-1 Inhibition of capsaicin-induced plasma extravasation in guinea pig ureter after intraperitoneal injection ChEMBL. 1378901
IC50 (binding) = 33.3 nM Binding affinity towards Tachykinin receptor 1 in human IM-9 cells using [3H]-substance P as ligand ChEMBL. 1378901
IC50 (binding) = 33.3 nM Binding affinity towards Tachykinin receptor 1 in human IM-9 cells using [3H]-substance P as ligand ChEMBL. 1378901
IC50 (binding) = 56 nM Binding potency of the compound against SP receptor in bovine caudate using [3H]- as radioligand ChEMBL. No reference
IC50 (binding) = 56 nM Binding potency of the compound against SP receptor in bovine caudate using [3H]- as radioligand ChEMBL. No reference
Inhibition (functional) = 38 % Inhibition of SP-induced plasma extravasation in guinea pig after peroral administration at a dose 15 mg/kg ChEMBL. 1378901
Inhibition (functional) < 43.9 % Inhibition of SP-induced salvation after intraperitoneal administration of the durg at a concentration of 50 mg/kg in rats ChEMBL. 1378901

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.