Detailed information for compound 84607

Basic information

Technical information
  • TDR Targets ID: 84607
  • Name: 8-[1-[4-(2,5-dichlorophenyl)piperazin-1-yl]pr opan-2-yl]-8-azaspiro[4.5]decane-7,9-dione
  • MW: 438.391 | Formula: C22H29Cl2N3O2
  • H donors: 0 H acceptors: 2 LogP: 4.52 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(N1C(=O)CC2(CC1=O)CCCC2)CN1CCN(CC1)c1cc(Cl)ccc1Cl
  • InChi: 1S/C22H29Cl2N3O2/c1-16(27-20(28)13-22(14-21(27)29)6-2-3-7-22)15-25-8-10-26(11-9-25)19-12-17(23)4-5-18(19)24/h4-5,12,16H,2-3,6-11,13-15H2,1H3
  • InChiKey: RPADCEVSPXUEKK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 8-[2-[4-(2,5-dichlorophenyl)piperazin-1-yl]-1-methyl-ethyl]-8-azaspiro[4.5]decane-7,9-dione
  • 8-[2-[4-(2,5-dichlorophenyl)-1-piperazinyl]-1-methylethyl]-8-azaspiro[4.5]decane-7,9-dione
  • 8-[2-[4-(2,5-dichlorophenyl)piperazino]-1-methyl-ethyl]-8-azaspiro[4.5]decane-7,9-quinone
  • 8-[2-[4-(2,5-dichlorophenyl)piperazin-1-yl]-1-methyl-ethyl]-8-azaspiro[4.5]decane-7,9-quinone

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens adrenoceptor alpha 1B Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled Starlite/ChEMBL References
Rattus norvegicus Alpha-1d adrenergic receptor Starlite/ChEMBL References
Rattus norvegicus Alpha-1a adrenergic receptor Starlite/ChEMBL References
Homo sapiens adrenoceptor alpha 1A Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni amine GPCR Get druggable targets OG5_128924 All targets in OG5_128924
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Get druggable targets OG5_128924 All targets in OG5_128924
Schistosoma japonicum expressed protein Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum Alpha-1D adrenergic receptor, putative Get druggable targets OG5_128924 All targets in OG5_128924
Echinococcus granulosus biogenic amine 5HT receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum ko:K04153 5-hydroxytryptamine (serotonin) receptor 1A, putative Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum Octopamine receptor, putative Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma mansoni biogenic amine (5HT) receptor Get druggable targets OG5_133249 All targets in OG5_133249
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus rhodopsin orphan GPCR Alpha-1a adrenergic receptor   466 aa 418 aa 20.3 %
Echinococcus multilocularis neuropeptide Y receptor Alpha-1a adrenergic receptor   466 aa 419 aa 19.6 %
Echinococcus multilocularis g protein coupled receptor Alpha-1a adrenergic receptor   466 aa 414 aa 20.3 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Alpha-1a adrenergic receptor   466 aa 443 aa 31.2 %
Schistosoma japonicum FMRFamide receptor, putative Alpha-1a adrenergic receptor   466 aa 374 aa 19.5 %
Echinococcus granulosus biogenic amine 5HT receptor Alpha-1a adrenergic receptor   466 aa 418 aa 30.4 %
Echinococcus granulosus g protein coupled receptor Alpha-1a adrenergic receptor   466 aa 399 aa 20.8 %
Echinococcus granulosus g protein coupled receptor Alpha-1a adrenergic receptor   466 aa 414 aa 20.5 %
Echinococcus multilocularis g protein coupled receptor Alpha-1a adrenergic receptor   466 aa 398 aa 21.4 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Alpha-1a adrenergic receptor   466 aa 386 aa 31.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0064 0.0119 0.2619
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0005 0.0003
Schistosoma mansoni nephrin related 0.0054 0.0093 0.0093
Onchocerca volvulus LIM and SH3 domain protein homolog 0.0022 0.0009 0.0014
Brugia malayi Protein kinase domain containing protein 0.0024 0.0016 0.0016
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0005 0.0005
Brugia malayi larval opioid receptor 0.002 0.0005 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0683 1
Trypanosoma cruzi cdc2-related kinase 1 0.0093 0.0193 0.0237
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0042 0.0063 0.0063
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0064 0.0119 0.0118
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0032 0.0036 0.0036
Echinococcus granulosus tyrosine protein kinase HCK 0.0126 0.0277 0.0277
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0064 0.0119 0.2619
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0064 0.0119 0.2619
Brugia malayi Prion-like- 0.0096 0.0202 0.0202
Loa Loa (eye worm) fructose-1,6-bisphosphatase 0.3187 0.8143 0.8143
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0064 0.0119 0.2619
Echinococcus multilocularis tyrosine protein kinase pr2 0.0064 0.0119 0.0119
Brugia malayi Prion-like- 0.0042 0.0063 0.0063
Schistosoma mansoni single-minded 0.0053 0.0091 0.0091
Brugia malayi SH2 domain containing protein 0.0032 0.0036 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0037 0.0045
Schistosoma mansoni opsin-like receptor 0.002 0.0005 0.0005
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Toxoplasma gondii hypothetical protein 0.0039 0.0054 0.0066
Echinococcus multilocularis Immunoglobulin 0.0054 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0026 0.002 0.0024
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.002 0.0005 0.0005
Brugia malayi protein-tyrosine kinase 0.0022 0.0009 0.0009
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0065 0.0065
Schistosoma mansoni tyrosine kinase 0.018 0.0415 0.0415
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Brugia malayi P38 map kinase family protein 2 0.0527 0.1307 0.1307
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0022 0.0009 0.0008
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0064 0.0118 0.0116
Echinococcus multilocularis mitogen activated protein kinase 11 0.0527 0.1307 0.1307
Echinococcus granulosus epidermal growth factor receptor kinase 0.0022 0.0009 0.0009
Schistosoma mansoni biogenic amine (5HT) receptor 0.0167 0.0383 0.0383
Trypanosoma brucei Flagellum attachment zone protein 20 0.0064 0.0119 0.0146
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Echinococcus multilocularis G-protein coupled receptor, putative 0.002 0.0005 0.0005
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0064 0.0118 0.0118
Echinococcus multilocularis transfer RNA-Phe 0.0052 0.0088 0.0088
Plasmodium falciparum conserved protein, unknown function 0.0039 0.0054 0.1915
Onchocerca volvulus 0.0022 0.0009 0.0014
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0202 0.0201
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0116 0.4439
Echinococcus granulosus lachesin 0.0096 0.0202 0.0202
Trichomonas vaginalis protein kinase atn1, putative 0.0064 0.0119 0.1744
Echinococcus granulosus suppressor of cytokine signaling 7 0.0032 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.0027
Brugia malayi MAP kinase sur-1 0.0115 0.0249 0.0249
Loa Loa (eye worm) TK/DDR protein kinase 0.0064 0.0119 0.0118
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0683 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Brugia malayi Inositol-1 0.0041 0.0058 0.0058
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0118 0.0257 0.0257
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0014 0.0205
Loa Loa (eye worm) hypothetical protein 0.0064 0.0119 0.0118
Echinococcus granulosus fructose 16 bisphosphatase 1 0.3187 0.8143 0.8143
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.002 0.0024
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0164 0.0374 0.0374
Onchocerca volvulus 0.0042 0.0063 0.0178
Onchocerca volvulus 0.0039 0.0054 0.0151
Echinococcus granulosus tyrosine protein kinase Src64B 0.018 0.0415 0.0415
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0683 1
Onchocerca volvulus 0.0042 0.0063 0.0178
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Giardia lamblia Kinase, CMGC MAPK 0.0115 0.0249 0.8842
Echinococcus multilocularis epidermal growth factor receptor kinase 0.0022 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0432 0.6328
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0032 0.0036 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0683 1
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.1185 0.2999 0.3683
Brugia malayi kettin 0.0042 0.0063 0.0063
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0064 0.0119 0.2619
Schistosoma mansoni neuropeptide receptor 0.002 0.0005 0.0005
Echinococcus granulosus allatostatin A receptor 0.002 0.0005 0.0005
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.004 0.0058 0.0058
Schistosoma mansoni titin 0.0061 0.011 0.011
Echinococcus granulosus tyrosine protein kinase csk 0.0064 0.0119 0.0119
Loa Loa (eye worm) TK protein kinase 0.0126 0.0277 0.0276
Brugia malayi Cytochrome P450 family protein 0.0044 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0054 0.0093 0.0091
Echinococcus granulosus g protein coupled receptor 0.002 0.0005 0.0005
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0037 0.1301
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0116 0.0116
Schistosoma mansoni tyrosine kinase 0.0161 0.0367 0.0367
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0032 0.0036 0.0035
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0087 0.0087
Mycobacterium tuberculosis Probable dehydrogenase 0.0119 0.0258 0.8837
Echinococcus multilocularis tyrosine protein kinase Fyn 0.018 0.0415 0.0415
Echinococcus granulosus nostrin 0.0022 0.0009 0.0009
Echinococcus granulosus serotonin receptor 0.002 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Schistosoma mansoni protein tyrosine kinase 0.0064 0.0119 0.0119
Giardia lamblia Kinase, NEK 0.0064 0.0119 0.4227
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0119 0.1744
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0119 0.1744
Echinococcus granulosus mitogen activated protein kinase 3 0.0115 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0001
Echinococcus granulosus arachidonate 5 lipoxygenase 0.019 0.0443 0.0443
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.002 0.0005 0.0003
Echinococcus multilocularis g-protein coupled receptor 0.002 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0032 0.0036 0.0036
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0037 0.1301
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0042 0.0063 0.0062
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0022 0.0009 0.0009
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0064 0.0119 0.0119
Onchocerca volvulus 0.0032 0.0036 0.0097
Loa Loa (eye worm) intermediate filament protein 0.003 0.003 0.0029
Brugia malayi MH2 domain containing protein 0.0131 0.0291 0.0291
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Schistosoma mansoni tyrosine kinase 0.2148 0.5472 0.5472
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Onchocerca volvulus 0.0032 0.0036 0.0097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0005 0.0005
Loa Loa (eye worm) TK/RYK protein kinase 0.0064 0.0119 0.0118
Loa Loa (eye worm) hypothetical protein 0.0039 0.0054 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0005 0.0005
Schistosoma mansoni cell adhesion molecule 0.0096 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0064 0.0119 0.0118
Echinococcus granulosus microtubule associated protein 2 0.1455 0.3693 0.3693
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0037 0.0048 0.0048
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Schistosoma mansoni cell adhesion molecule 0.0042 0.0063 0.0063
Echinococcus multilocularis dnaJ subfamily B 0.0449 0.1109 0.1109
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0119 0.1744
Echinococcus granulosus signal transduction protein lnk realted 0.0032 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0042 0.0063 0.0063
Echinococcus granulosus tyrosine protein kinase 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Entamoeba histolytica hypothetical protein, conserved 0.0039 0.0054 0.1066
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0064 0.0119 0.0119
Plasmodium falciparum protein kinase, putative 0.0073 0.0141 0.4998
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Onchocerca volvulus Netrin receptor homolog 0.0058 0.0103 0.0302
Echinococcus granulosus SHC transforming protein 3 0.0032 0.0036 0.0036
Echinococcus multilocularis 0.0026 0.002 0.002
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0532 0.132 0.132
Onchocerca volvulus 0.003 0.003 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0119 0.1744
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0042 0.0063 0.0063
Loa Loa (eye worm) TK/EPH protein kinase 0.0273 0.0655 0.0654
Echinococcus granulosus SH2 motif 0.0032 0.0036 0.0036
Schistosoma mansoni tensin 0.0032 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0096 0.0202 0.02
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0054 0.0093 0.0093
Brugia malayi hypothetical protein 0.0028 0.0025 0.0025
Schistosoma mansoni sorting nexin 0.0022 0.0009 0.0009
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.0088 0.0088
Echinococcus granulosus titin 0.0042 0.0063 0.0063
Echinococcus multilocularis neuropeptide receptor A26 0.002 0.0005 0.0005
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0154 0.0349 0.0348
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Brugia malayi SH2 domain containing protein 0.0032 0.0036 0.0036
Echinococcus granulosus single minded 2 0.004 0.0055 0.0055
Brugia malayi putative neuropeptide receptor NPR1 0.002 0.0005 0.0005
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Echinococcus granulosus tyrosine protein kinase Fyn 0.018 0.0415 0.0415
Echinococcus granulosus titin 0.0042 0.0063 0.0063
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Leishmania major 0.3187 0.8143 1
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0026 0.002 0.0754
Onchocerca volvulus 0.0052 0.0088 0.0255
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0026 0.002 0.0672
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Echinococcus granulosus cyclin dependent kinase 0.0093 0.0193 0.0193
Echinococcus multilocularis epidermal growth factor receptor 0.391 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0135
Brugia malayi Protein kinase domain containing protein 0.0097 0.0202 0.0202
Echinococcus granulosus tyrosine protein kinase Lyn 0.0188 0.0437 0.0437
Toxoplasma gondii cytochrome p450 superfamily protein 0.0026 0.002 0.0024
Echinococcus granulosus mitogen activated protein kinase 11 0.0527 0.1307 0.1307
Brugia malayi G-protein coupled receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Echinococcus granulosus tyrosine protein kinase csk 0.0064 0.0119 0.0119
Schistosoma mansoni protein kinase 0.0068 0.0129 0.0129
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Brugia malayi Dopamine receptor protein 2 0.002 0.0005 0.0005
Echinococcus granulosus insulin receptor 0.1391 0.3527 0.3527
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0096 0.0202 0.02
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Loa Loa (eye worm) hypothetical protein 0.0064 0.0119 0.0118
Echinococcus granulosus thyrotropin releasing hormone receptor 0.002 0.0005 0.0005
Schistosoma mansoni tyrosine kinase 0.2084 0.5307 0.5307
Echinococcus granulosus hypothetical protein 0.0119 0.026 0.026
Brugia malayi hypothetical protein 0.0054 0.0093 0.0093
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0508 0.126 0.126
Plasmodium vivax tyrosine kinase-like protein, putative 0.0064 0.0119 0.4227
Brugia malayi cytokine inducible SH2-containing protein 5 0.0032 0.0036 0.0036
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Brugia malayi Serotonin/octopamine receptor family protein 7 0.002 0.0005 0.0005
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0527 0.1307 0.1306
Loa Loa (eye worm) hypothetical protein 0.0231 0.0546 0.0545
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0037 0.0537
Trypanosoma cruzi cdc2-related kinase 3 0.0093 0.0193 0.0237
Schistosoma mansoni jumonji domain containing protein 0.0065 0.012 0.012
Loa Loa (eye worm) CAMK protein kinase 0.0061 0.011 0.0108
Schistosoma mansoni hypothetical protein 0.002 0.0005 0.0005
Schistosoma mansoni metabotropic glutamate receptor 0.002 0.0005 0.0005
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0106 0.0227 0.0227
Loa Loa (eye worm) STAT protein 0.0032 0.0036 0.0035
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0005 0.0005
Schistosoma mansoni signal transduction protein lnk-related 0.0032 0.0036 0.0036
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0106 0.0227 0.0227
Echinococcus granulosus cytochrome P450 2K1 0.0026 0.002 0.002
Schistosoma mansoni suppressor of cytokine signaling 0.0032 0.0036 0.0036
Echinococcus granulosus metabotropic glutamate receptor 2 0.0034 0.0041 0.0041
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0261 0.5995
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0119 0.0118
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0054 0.0092 0.0091
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0047 0.1611
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0005 0.0005
Plasmodium falciparum tyrosine kinase-like protein 0.0064 0.0119 0.4227
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0124 0.0123
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0026 0.002 0.0672
Brugia malayi Metabotropic glutamate receptor precursor. 0.0041 0.0058 0.0058
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0026 0.002 0.0754
Loa Loa (eye worm) TK protein kinase 0.0064 0.0119 0.0118
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0063 0.0116 0.0116
Onchocerca volvulus 0.0039 0.0054 0.0151
Plasmodium falciparum protein kinase, putative 0.0064 0.0119 0.4227
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0037 0.0537
Brugia malayi Thioredoxin reductase 0.0052 0.0087 0.0087
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Schistosoma mansoni formin binding protein and related proteins 0.0022 0.0009 0.0009
Entamoeba histolytica receptor protein kinase, putative 0.0064 0.0119 0.2619
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0202 0.0201
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0065 0.0065
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0261 0.032
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis tyrosine protein kinase shark 0.0097 0.0202 0.0202
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0026 0.002 0.0754
Brugia malayi AKH receptor 0.002 0.0005 0.0005
Schistosoma mansoni adenoreceptor 0.002 0.0005 0.0005
Echinococcus multilocularis tyrosine protein kinase csk 0.0064 0.0119 0.0119
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0096 0.0202 0.02
Schistosoma mansoni amine GPCR 0.002 0.0005 0.0005
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.002 0.0005 0.0005
Echinococcus granulosus kinase suppressor of Ras 1 0.0064 0.0119 0.0119
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.0022 0.0009 0.0009
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0064 0.0119 0.0119
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0026 0.002 0.0672
Loa Loa (eye worm) SH2 domain-containing protein 0.0032 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Echinococcus multilocularis ephrin type A receptor 4 A 0.0267 0.064 0.064
Brugia malayi Tyrosine-protein kinase abl-1 0.0269 0.0644 0.0644
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0042 0.0063 0.0062
Onchocerca volvulus 0.0097 0.0202 0.0603
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0005 0.0005
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0508 0.126 0.126
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0063 0.0116 0.0116
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0063 0.0063
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0005 0.0005
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0064 0.0119 0.0119
Onchocerca volvulus Peroxidasin homolog 0.0042 0.0063 0.0178
Echinococcus granulosus tyrosine protein kinase pr2 0.0064 0.0119 0.0119
Echinococcus granulosus epidermal growth factor receptor 0.391 1 1
Toxoplasma gondii kringle domain-containing protein 0.0039 0.0054 0.0066
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0064 0.0119 0.2619
Schistosoma mansoni dreadlocks/dock 0.0022 0.0009 0.0009
Echinococcus granulosus activin receptor type 0.0073 0.0141 0.0141
Schistosoma mansoni tensin-related 0.0032 0.0036 0.0036
Echinococcus granulosus fibroblast growth factor receptor 4 0.0064 0.0119 0.0119
Onchocerca volvulus 0.0064 0.0119 0.035
Schistosoma mansoni alpha-1 adrenergic receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Brugia malayi follicle stimulating hormone receptor 0.002 0.0005 0.0005
Brugia malayi Disorganized muscle protein 1 0.0042 0.0063 0.0063
Giardia lamblia Aurora kinase 0.0121 0.0265 0.9419
Schistosoma mansoni biogenic amine receptor 0.002 0.0005 0.0005
Echinococcus granulosus hematopoietic lineage cell specific protein 0.0022 0.0009 0.0009
Echinococcus multilocularis dual specificity protein kinase clk2 0.0128 0.0282 0.0282
Echinococcus multilocularis fructose 1,6 bisphosphatase 1 0.3187 0.8143 0.8143
Schistosoma mansoni histamine h1 receptor 0.002 0.0005 0.0005
Plasmodium falciparum protein kinase, putative 0.0064 0.0119 0.4227
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0054 0.0093 0.0093
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0037 0.0045
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Schistosoma mansoni peroxidasin 0.0054 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0096 0.0202 0.02
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0026 0.002 0.0672
Plasmodium falciparum glutathione reductase 0.0052 0.0087 0.3097
Echinococcus multilocularis twitchin 0.0051 0.0085 0.0085
Plasmodium falciparum serine/threonine protein kinase, putative 0.0121 0.0265 0.9419
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0037 0.0537
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0037 0.0654
Echinococcus granulosus hypothetical protein 0.002 0.0005 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Giardia lamblia Kinase, CMGC CDK 0.0093 0.0193 0.6862
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0125 0.0124
Echinococcus multilocularis tachykinin peptides receptor 99D 0.002 0.0005 0.0005
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0073 0.0141 0.0141
Echinococcus granulosus titin 0.0061 0.011 0.011
Schistosoma mansoni amine GPCR 0.002 0.0005 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0249 0.3647
Schistosoma mansoni basigin related 0.0054 0.0093 0.0093
Echinococcus granulosus titin 0.0042 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0064 0.0119 0.0118
Schistosoma mansoni SH2A 0.0032 0.0036 0.0036
Echinococcus granulosus g protein coupled receptor 0.002 0.0005 0.0005
Onchocerca volvulus 0.0043 0.0065 0.0185
Loa Loa (eye worm) protein-tyrosine kinase 0.0022 0.0009 0.0008
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0054 0.0093 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0432 0.6328
Echinococcus multilocularis kinase suppressor of Ras 1 0.0064 0.0119 0.0119
Schistosoma mansoni C-fyn 0.0022 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0054 0.0093 0.0093
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0063 0.0116 0.0142
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0026 0.002 0.0754
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0135
Schistosoma mansoni lipoxygenase 0.019 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Schistosoma mansoni cpg binding protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) TK protein kinase 0.0064 0.0119 0.0118
Brugia malayi serine/threonine-protein kinase 6 0.0121 0.0265 0.0265
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Brugia malayi Protein kinase domain containing protein 0.0097 0.0202 0.0202
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0064 0.0119 0.0119
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0009 0.0009
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) transcription factor SMAD2 0.0131 0.0291 0.029
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0121 0.0265 0.6107
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis mitogen activated protein kinase 11 0.0527 0.1307 0.1307
Onchocerca volvulus 0.1186 0.3001 0.9161
Leishmania major protein kinase, putative 0.0022 0.0011 0.0014
Echinococcus granulosus intermediate filament protein 0.003 0.003 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0301 0.0728 0.0728
Schistosoma mansoni hypothetical protein 0.0042 0.0063 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0005 0.0005
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0284 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0167 0.0383 0.0381
Schistosoma mansoni shc transforming protein 0.0032 0.0036 0.0036
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.002 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.002 0.0005 0.0005
Loa Loa (eye worm) TK protein kinase 0.0064 0.0119 0.0118
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.2148 0.5472 0.5472
Schistosoma mansoni adapter molecule crk 0.0054 0.0092 0.0092
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Echinococcus granulosus neuropeptide receptor 0.002 0.0005 0.0005
Echinococcus granulosus dual specificity 0.0185 0.0429 0.0429
Echinococcus multilocularis neuropeptide s receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) TK/ROR protein kinase 0.0107 0.0228 0.0227
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0026 0.002 0.0024
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0054 0.0093 0.0093
Echinococcus multilocularis Immunoglobulin 0.0054 0.0093 0.0093
Plasmodium vivax cysteine repeat modular protein 3, putative 0.0039 0.0054 0.1915
Schistosoma mansoni tyrosine kinase 0.0068 0.0129 0.0129
Brugia malayi protein-tyrosine kinase 0.0158 0.036 0.036
Echinococcus multilocularis 0.1196 0.3027 0.3027
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0128 0.0282 0.0346
Brugia malayi Protein kinase domain containing protein 0.0097 0.0202 0.0202
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Schistosoma mansoni cell polarity protein 0.0022 0.0009 0.0009
Schistosoma mansoni tyrosine kinase 0.391 1 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0032 0.0036 0.0036
Schistosoma mansoni titin 0.0052 0.0088 0.0088
Brugia malayi Immunoglobulin I-set domain containing protein 0.0096 0.0202 0.0202
Giardia lamblia Kinase, NEK 0.0064 0.0119 0.4239
Loa Loa (eye worm) hypothetical protein 0.0039 0.0054 0.0053
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0064 0.0119 0.2619
Echinococcus granulosus hemicentin 1 0.0096 0.0202 0.0202
Brugia malayi GnHR receptor homolog 0.002 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0073 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0282 0.4125
Loa Loa (eye worm) hypothetical protein 0.0054 0.0093 0.0091
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0026 0.002 0.0754
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Loa Loa (eye worm) glutathione reductase 0.0052 0.0087 0.0086
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0026 0.002 0.0672
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0115 0.0249 0.0306
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0061 0.011 0.0108
Echinococcus multilocularis neuroglian 0.0196 0.0458 0.0458
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0073 0.0141 0.0141
Schistosoma mansoni myosin-binding protein-related 0.0052 0.0088 0.0088
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Brugia malayi serine/threonine kinase 12 0.0121 0.0265 0.0265
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0026 0.002 0.0672
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.0261 0.032
Schistosoma mansoni nephrin related 0.0042 0.0063 0.0063
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0154 0.0349 0.0349
Brugia malayi Guanylyl cyclase protein 23 0.0068 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Schistosoma mansoni eps8-related protein 0.0022 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0064 0.0119 0.2619
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0185 0.0429 0.0526
Brugia malayi PAS domain containing protein 0.0053 0.0091 0.0091
Trichomonas vaginalis CMGC family protein kinase 0.0093 0.0193 0.2831
Schistosoma mansoni titin 0.0042 0.0063 0.0063
Loa Loa (eye worm) guanylate kinase 0.0022 0.0009 0.0008
Brugia malayi hypothetical protein 0.0064 0.0119 0.0119
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.0022 0.0009 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Mycobacterium ulcerans putative regulatory protein 0.004 0.0055 0.2125
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0026 0.002 0.0754
Echinococcus granulosus retinal guanylyl cyclase 2 0.0064 0.0119 0.0119
Echinococcus multilocularis microtubule associated protein 2 0.1455 0.3693 0.3693
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0125 0.0154
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0042 0.0063 0.0063
Loa Loa (eye worm) cytochrome P450 family protein 0.0044 0.0067 0.0066
Echinococcus granulosus Immunoglobulin 0.0054 0.0093 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0058 0.085
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0009 0.0011
Brugia malayi 6-phosphofructokinase 0.012 0.0261 0.0261
Schistosoma mansoni biogenic amine receptor 0.002 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0026 0.002 0.0672
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0032 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0164 0.0374 0.0373
Brugia malayi integrin-linked kinase 0.0064 0.0119 0.0119
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0106 0.0227 0.0227
Echinococcus multilocularis aurora kinase A 0.0121 0.0265 0.0265
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0087 0.0107
Echinococcus multilocularis lachesin 0.0096 0.0202 0.0202
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0005 0.0005
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Echinococcus multilocularis c src tyrosine kinase 0.0118 0.0257 0.0257
Brugia malayi hypothetical protein 0.0032 0.0036 0.0036
Brugia malayi gonadotropin-releasing hormone receptor 2 0.002 0.0005 0.0005
Echinococcus multilocularis somatostatin receptor 0.002 0.0005 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0063 0.0063
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.002 0.0005 0.0005
Brugia malayi Cytochrome P450 family protein 0.0026 0.002 0.002
Echinococcus granulosus MAM 0.0028 0.0025 0.0025
Entamoeba histolytica serine/threonine kinase, putative 0.0064 0.0119 0.2619
Loa Loa (eye worm) hypothetical protein 0.0096 0.0202 0.02
Echinococcus multilocularis mitogen activated protein kinase 3 0.0115 0.0249 0.0249
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0064 0.0119 0.0119
Echinococcus multilocularis tyrosine protein kinase otk 0.0096 0.0202 0.0202
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.0022 0.0009 0.0009
Onchocerca volvulus 0.0042 0.0063 0.0178
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0119 0.0118
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0022 0.0009 0.0009
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0065 0.0065
Onchocerca volvulus Putative cortactin 0.0022 0.0009 0.0014
Brugia malayi Leucine Rich Repeat family protein 0.0042 0.0063 0.0063
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Trichomonas vaginalis protein tyrosine kinase, putative 0.0064 0.0119 0.1744
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0026 0.002 0.0672
Echinococcus granulosus activated cdc42 kinase 1 0.0064 0.0119 0.0119
Entamoeba histolytica serine/threonine kinase, putative 0.0064 0.0119 0.2619
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0115 0.0249 0.0306
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Schistosoma mansoni protein kinase 0.0064 0.0119 0.0119
Echinococcus granulosus biogenic amine 5HT receptor 0.0167 0.0383 0.0383
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0261 0.3817
Brugia malayi Immunoglobulin I-set domain containing protein 0.0064 0.0118 0.0118
Toxoplasma gondii GCC2 and GCC3 domain-containing protein 0.0039 0.0054 0.0066
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0054 0.0093 0.0093
Loa Loa (eye worm) one IG domain family member 0.0042 0.0063 0.0062
Echinococcus granulosus insulin growth factor 1 receptor beta 0.14 0.3552 0.3552
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0119 0.1744
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0042 0.0063 0.0062
Schistosoma mansoni lamin 0.003 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0243 0.0579 0.0578
Loa Loa (eye worm) hypothetical protein 0.0154 0.0349 0.0348
Echinococcus multilocularis hemicentin 1 0.0096 0.0202 0.0202
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0054 0.0093 0.0091
Schistosoma mansoni suppressor of cytokine signaling 0.0032 0.0036 0.0036
Echinococcus granulosus peroxidasin 0.0096 0.0202 0.0202
Entamoeba histolytica ankyrin repeat protein 0.0064 0.0119 0.2619
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Brugia malayi Myb-like DNA-binding domain containing protein 0.0042 0.0063 0.0063
Echinococcus granulosus dual specificity protein kinase clk2 0.0128 0.0282 0.0282
Schistosoma mansoni hypothetical protein 0.0186 0.0432 0.0432
Loa Loa (eye worm) LAD-2 short isoform 0.0054 0.0093 0.0091
Schistosoma mansoni ephrin receptor 0.0228 0.054 0.054
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0064 0.0119 0.0119
Onchocerca volvulus 0.0032 0.0035 0.0092
Loa Loa (eye worm) glutamate receptor 0.0041 0.0058 0.0057
Brugia malayi Raf kinase 0.0293 0.0706 0.0706
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0432 0.6328
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0063 0.0063
Schistosoma mansoni biogenic amine receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) TK/INSR protein kinase 0.1391 0.3527 0.3526
Echinococcus granulosus NCK adaptor protein 0.0054 0.0092 0.0092
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0073 0.0141 0.0173
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Schistosoma mansoni inositol monophosphatase 0.0041 0.0058 0.0058
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0005 0.0005
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.002 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0121 0.0265 0.0265
Brugia malayi intermediate filament protein 0.003 0.003 0.003
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0249 0.3647
Echinococcus multilocularis cyclin dependent kinase 1 0.0093 0.0193 0.0193
Onchocerca volvulus 0.0097 0.0202 0.0603
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0261 0.0259
Schistosoma mansoni basigin related 0.0054 0.0093 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0683 1
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0119 0.0118
Entamoeba histolytica hypothetical protein 0.0064 0.0119 0.2619
Brugia malayi Heparan sulfate 0.0054 0.0093 0.0093
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0107 0.0132
Schistosoma mansoni opsin-like receptor 0.002 0.0005 0.0005
Onchocerca volvulus 0.0061 0.011 0.0321
Schistosoma mansoni tyrosine kinase 0.0097 0.0202 0.0202
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0005 0.0005
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0005 0.0003
Echinococcus granulosus SH2 motif 0.0032 0.0036 0.0036
Schistosoma mansoni cpg binding protein 0.0033 0.0039 0.0039
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0119 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0121 0.0265 0.9419
Loa Loa (eye worm) hypothetical protein 0.0154 0.0349 0.0348
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0094 0.0194 0.0194
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0115 0.0249 0.0248
Echinococcus multilocularis SH2 motif 0.0032 0.0036 0.0036
Leishmania major protein kinase, putative 0.0073 0.0141 0.0173
Schistosoma mansoni protein kinase 0.0064 0.0119 0.0119
Echinococcus granulosus tyrosine protein kinase Src42A 0.0094 0.0194 0.0194
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0009 0.0009
Echinococcus granulosus somatostatin receptor 0.002 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0005 0.0005
Echinococcus granulosus down syndrome cell adhesion 0.0042 0.0063 0.0063
Plasmodium falciparum cysteine repeat modular protein 2 0.0039 0.0054 0.1915
Loa Loa (eye worm) AUR protein kinase 0.0121 0.0265 0.0264
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus granulosus N chimaerin 0.004 0.0058 0.0058
Entamoeba histolytica protein kinase, putative 0.0121 0.0265 0.6107
Brugia malayi neuropeptide F receptor 0.002 0.0005 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Echinococcus multilocularis tyrosine protein kinase Src64B 0.018 0.0415 0.0415
Echinococcus granulosus receptor type guanylyl cyclase 0.0068 0.0129 0.0129
Brugia malayi Immunoglobulin I-set domain containing protein 0.0054 0.0093 0.0093
Entamoeba histolytica serine/threonine kinase, putative 0.0064 0.0119 0.2619
Brugia malayi Src substrate cortactin 0.0022 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0052 0.0088 0.0088
Echinococcus multilocularis transfer RNA-Ala 0.0022 0.0009 0.0009
Echinococcus multilocularis integrin linked protein kinase 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0508 0.126 0.1259
Entamoeba histolytica cell division protein kinase 2, putative 0.0093 0.0193 0.4389
Schistosoma mansoni intermediate filament proteins 0.003 0.003 0.003
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0193 0.0193
Entamoeba histolytica hypothetical protein 0.0185 0.0429 1
Trypanosoma brucei cytochrome P450, putative 0.0044 0.0067 0.0082
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0022 0.0009 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0265 0.0265
Echinococcus granulosus fmrfamide receptor 0.002 0.0005 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0063 0.0063
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Brugia malayi GCC2 and GCC3 family protein 0.0039 0.0054 0.0054
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Schistosoma mansoni microtubule-associated protein tau 0.1455 0.3693 0.3693
Onchocerca volvulus 0.0037 0.005 0.0138
Schistosoma mansoni septate junction protein 0.0054 0.0093 0.0093
Brugia malayi Immunoglobulin I-set domain containing protein 0.0096 0.0202 0.0202
Trichomonas vaginalis CMGC family protein kinase 0.0093 0.0193 0.2831
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0026 0.002 0.0754
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.002 0.0005 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0005 0.0005
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0037 0.0537
Trypanosoma brucei Pseudokinase, putative 0.0064 0.0119 0.0146
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0116 0.4439
Brugia malayi putative neuropeptide receptor 0.002 0.0005 0.0005
Schistosoma mansoni tyrosine kinase 0.018 0.0415 0.0415
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0001 0.0001
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0249 0.0306
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0527 0.1307 0.1605
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0119 0.0258 0.8837
Brugia malayi G protein-coupled receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0058 0.0058
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.018 0.0415 0.0415
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0093 0.0193 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0119 0.1744
Echinococcus multilocularis tyrosine protein kinase 0.0064 0.0119 0.0119
Onchocerca volvulus 0.0064 0.0119 0.035
Echinococcus granulosus integrin linked protein kinase 0.0064 0.0119 0.0119
Brugia malayi tRNA modification GTPase TrmE family protein 0.0032 0.0036 0.0036
Echinococcus granulosus expressed conserved protein 0.0032 0.0036 0.0036
Brugia malayi hypothetical protein 0.0097 0.0202 0.0202
Schistosoma mansoni tyrosine kinase 0.0499 0.1237 0.1237
Onchocerca volvulus 0.0032 0.0036 0.0097
Schistosoma mansoni hypothetical protein 0.0054 0.0093 0.0093
Brugia malayi Sex muscle abnormal protein 5 0.0054 0.0092 0.0092
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0054 0.1915
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0282 0.0282
Echinococcus multilocularis roundabout 2 0.0106 0.0227 0.0227
Schistosoma mansoni neuropeptide f receptor 76f 0.002 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0202 0.0201
Toxoplasma gondii STE kinase 0.0064 0.0119 0.0146
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0037 0.1301
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0032 0.0036 0.0035
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0026 0.002 0.0754
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0032 0.0036 0.0097
Echinococcus granulosus tensin 0.0032 0.0036 0.0036
Echinococcus multilocularis MAM 0.0028 0.0025 0.0025
Brugia malayi SH2 domain containing protein 0.0032 0.0036 0.0036
Loa Loa (eye worm) TK protein kinase 0.0064 0.0119 0.0118
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0106 0.0227 0.0226
Toxoplasma gondii fructose-bisphospatase II 0.3187 0.8143 1
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0043 0.0065 0.0064
Schistosoma mansoni signal transducing adapter molecule (stam) 0.0022 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.002 0.0005 0.0003
Loa Loa (eye worm) animal heme peroxidase 0.0042 0.0063 0.0062
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0064 0.0119 0.0119
Echinococcus multilocularis tyrosine protein kinase Src42A 0.018 0.0415 0.0415
Schistosoma mansoni hypothetical protein 0.0054 0.0093 0.0093
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0005 0.0005
Echinococcus granulosus insulin growth factor binding 0.0042 0.0063 0.0063
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Brugia malayi Variant SH3 domain containing protein 0.0054 0.0092 0.0092
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0124 0.0124
Loa Loa (eye worm) TK protein kinase 0.0064 0.0119 0.0118
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0185 0.0429 0.0427
Echinococcus multilocularis cyclin dependent kinase 0.0093 0.0193 0.0193
Onchocerca volvulus 0.0042 0.0063 0.0178
Schistosoma mansoni GTPase activating protein 0.0032 0.0036 0.0036
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0058 0.085
Schistosoma mansoni hypothetical protein 0.0054 0.0093 0.0093
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0032 0.0036 0.0036
Schistosoma mansoni amine GPCR 0.002 0.0005 0.0005
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0058 0.0071
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.0022 0.0009 0.0009
Echinococcus granulosus roundabout 2 0.0106 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.0164 0.0374 0.0373
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Echinococcus multilocularis tyrosine protein kinase Fgr 0.018 0.0415 0.0415
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0097 0.0202 0.0202
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0022 0.0011 0.0014
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.004 0.0058 0.0058
Loa Loa (eye worm) RecQ helicase 0.0023 0.0014 0.0013
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0026 0.002 0.0754
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0064 0.0119 0.0119
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0064 0.0119 0.0119
Schistosoma mansoni septate junction protein 0.0096 0.0202 0.0202
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Echinococcus granulosus mitogen activated protein kinase 0.0115 0.0249 0.0249
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0128 0.0282 0.0346
Echinococcus multilocularis neuroglian 0.0106 0.0227 0.0227
Echinococcus multilocularis insulin growth factor binding 0.0042 0.0063 0.0063
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0039 0.0054 0.1915
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Loa Loa (eye worm) hypothetical protein 0.0085 0.0172 0.017
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Leishmania major hypothetical protein, conserved 0.0064 0.0119 0.0146
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0096 0.0202 0.0602
Brugia malayi Immunoglobulin domain containing protein 0.0054 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0119 0.1744
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase 14 0.0527 0.1307 0.1307
Echinococcus multilocularis NCK adaptor protein 0.0054 0.0092 0.0092
Loa Loa (eye worm) TK/EGFR protein kinase 0.391 1 1
Echinococcus multilocularis G protein coupled receptor 139 0.002 0.0005 0.0005
Mycobacterium tuberculosis Probable oxidoreductase 0.0132 0.0292 1
Schistosoma mansoni tyrosine kinase 0.1391 0.3527 0.3527
Plasmodium vivax glutathione reductase, putative 0.0052 0.0087 0.3097
Echinococcus granulosus c src tyrosine kinase 0.0118 0.0257 0.0257
Schistosoma mansoni titin 0.0042 0.0063 0.0063
Brugia malayi Guanylate kinase family protein 0.0022 0.0009 0.0009
Giardia lamblia Kinase, CMGC CLK 0.0128 0.0282 1
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0026 0.002 0.0754
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0261 0.0261
Echinococcus granulosus tyrosine protein kinase ABL1 0.0532 0.132 0.132
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0032 0.0036 0.0097
Echinococcus multilocularis peroxidasin 0.0096 0.0202 0.0202
Schistosoma mansoni fructose-16-bisphosphatase-related 0.3187 0.8143 0.8143
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.002 0.0005 0.0005
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0058 0.0058
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0508 0.126 0.126
Brugia malayi Variant SH3 domain containing protein 0.004 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.003 0.003 0.0029
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Entamoeba histolytica serine/threonine kinase, putative 0.0064 0.0119 0.2619
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.002 0.0005 0.0005
Schistosoma mansoni septate junction protein 0.0096 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0087 0.0177 0.0176
Echinococcus granulosus suppressor of cytokine signaling 6 0.0032 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0042 0.0063 0.0063
Schistosoma mansoni polycystin 1-related 0.0043 0.0065 0.0065
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0175 0.0175
Leishmania major trypanothione reductase 0.0052 0.0087 0.0107
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0065 0.0064
Loa Loa (eye worm) follicle stimulating hormone receptor 0.002 0.0005 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0202 0.0201
Echinococcus granulosus nuclear factor of activated T cells 5 0.0081 0.0162 0.0162
Schistosoma mansoni hypothetical protein 0.0054 0.0093 0.0093
Schistosoma mansoni hypothetical protein 0.0054 0.0093 0.0093
Echinococcus multilocularis SHC transforming protein 3 0.0032 0.0036 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0261 0.3817
Loa Loa (eye worm) RGC/RGC protein kinase 0.0068 0.0129 0.0128
Loa Loa (eye worm) hypothetical protein 0.0039 0.0054 0.0053
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0063 0.0063
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0058 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Schistosoma mansoni hypothetical protein 0.0064 0.0119 0.0119
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.002 0.0005 0.0005
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Plasmodium falciparum thioredoxin reductase 0.0052 0.0087 0.3097
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Schistosoma mansoni hypothetical protein 0.002 0.0005 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Echinococcus multilocularis g protein coupled receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0128 0.0282 0.0281
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Brugia malayi hypothetical protein 0.0064 0.0119 0.0119
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0119 0.0117
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0249 0.3647
Brugia malayi RhoGAP domain containing protein 0.004 0.0058 0.0058
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0064 0.0119 0.0119
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.3187 0.8143 1
Echinococcus granulosus basement membrane specific heparan sulfate 0.0054 0.0093 0.0093
Schistosoma mansoni growth hormone secretagogue receptor 0.002 0.0005 0.0005
Schistosoma mansoni cell adhesion molecule 0.0218 0.0513 0.0513
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0115 0.0249 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0119 0.1744
Echinococcus multilocularis netrin receptor unc 5 0.007 0.0133 0.0133
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0527 0.1307 0.1605
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0005 0.0005
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0158 0.036 0.036
Echinococcus granulosus tyrosine protein kinase Srms 0.0097 0.0202 0.0202
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0063 0.0063
Echinococcus multilocularis lamin dm0 0.003 0.003 0.003
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Onchocerca volvulus 0.0064 0.0119 0.035
Loa Loa (eye worm) hypothetical protein 0.0054 0.0093 0.0091
Loa Loa (eye worm) TYRA-2 protein 0.002 0.0005 0.0003
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Brugia malayi Receptor family ligand binding region containing protein 0.0068 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Echinococcus multilocularis mitogen activated protein kinase 14 0.0527 0.1307 0.1307
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0176 0.0407 0.0406
Brugia malayi sulfakinin receptor protein 0.002 0.0005 0.0005
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0065 0.0065
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0005 0.0003
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0009 0.0009
Trypanosoma cruzi cytochrome P450, putative 0.0044 0.0067 0.0082
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0081 0.0162 0.0162
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0063 0.0063
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0064 0.0119 0.0119
Echinococcus multilocularis tyrosine protein kinase HCK 0.0126 0.0277 0.0277
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.0022 0.0009 0.0009
Schistosoma mansoni protein kinase 0.0064 0.0119 0.0119
Giardia lamblia Kinase 0.0064 0.0119 0.4227
Onchocerca volvulus 0.0022 0.0009 0.0014
Schistosoma mansoni tensin 0.0032 0.0036 0.0036
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0124 0.0124
Brugia malayi hypothetical protein 0.0164 0.0374 0.0374
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0064 0.0119 0.0119
Brugia malayi Myosin tail family protein 0.0022 0.0009 0.0009
Echinococcus multilocularis neuropeptide FF receptor 2 0.002 0.0005 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Loa Loa (eye worm) hypothetical protein 0.025 0.0597 0.0596
Loa Loa (eye worm) TK protein kinase 0.0107 0.0228 0.0227
Trypanosoma cruzi aurora B kinase, putative 0.0121 0.0265 0.0326
Plasmodium falciparum protein serine/threonine kinase-1 0.0128 0.0282 1
Echinococcus granulosus aurora kinase A 0.0121 0.0265 0.0265
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.0088 0.0088
Plasmodium falciparum cysteine repeat modular protein 1 0.0039 0.0054 0.1915
Brugia malayi SH2 domain containing protein 0.0097 0.0202 0.0202
Trypanosoma brucei protein kinase, putative 0.0073 0.0141 0.0173
Echinococcus multilocularis serotonin receptor 0.0167 0.0383 0.0383
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0005 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Schistosoma mansoni hemicentin 0.0052 0.0088 0.0088
Plasmodium vivax protein kinase, putative 0.0077 0.0152 0.54
Schistosoma mansoni hypothetical protein 0.0449 0.1109 0.1109
Brugia malayi SRC-1 0.018 0.0415 0.0415
Schistosoma mansoni slit-robo rho gtpase activating protein 0.0022 0.0009 0.0009
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0037 0.1301
Schistosoma mansoni growth factor receptor-bound protein 0.0054 0.0092 0.0092
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0005 0.0005
Schistosoma mansoni myosin xvIII 0.002 0.0005 0.0005
Brugia malayi CXXC zinc finger family protein 0.0032 0.0035 0.0035
Echinococcus granulosus nephrin 0.0052 0.0088 0.0088
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0026 0.002 0.0024
Leishmania major cytochrome p450-like protein 0.0026 0.002 0.0024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0096 0.0202 0.0202
Schistosoma mansoni hypothetical protein 0.0042 0.0063 0.0063
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0243 0.0579 0.0578
Brugia malayi Fibronectin type III domain containing protein 0.0164 0.0374 0.0374
Echinococcus multilocularis Immunoglobulin 0.0154 0.0349 0.0349
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0193 0.0193
Loa Loa (eye worm) RGC/RGC protein kinase 0.0068 0.0129 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0135
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0064 0.0119 0.1744
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0202 0.0201
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0093 0.0193 0.0192
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0068 0.0129 0.038
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Echinococcus multilocularis expressed protein 0.0022 0.0009 0.0009
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0249 0.3647
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0064 0.0119 0.2619
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Schistosoma mansoni growth factor receptor-bound protein 0.0054 0.0092 0.0092
Schistosoma mansoni inositol monophosphatase 0.0041 0.0058 0.0058
Echinococcus granulosus dro:myosuppressin receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) SH2 domain-containing protein 0.0032 0.0036 0.0035
Schistosoma mansoni titin 0.0042 0.0063 0.0063
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0096 0.0202 0.0202
Entamoeba histolytica tyrosin kinase, putative 0.0064 0.0119 0.2619
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0058 0.085
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Echinococcus multilocularis tyrosine protein kinase Fyn 0.018 0.0415 0.0415
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0128 0.0282 0.0346
Schistosoma mansoni amine GPCR 0.062 0.1546 0.1546
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0037 1
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0432 0.6328
Echinococcus multilocularis natriuretic peptide receptor 1 0.0064 0.0119 0.0119
Entamoeba histolytica protein kinase, putative 0.0041 0.0058 0.1167
Brugia malayi SH2 domain containing protein 0.0032 0.0036 0.0036
Entamoeba histolytica protein kinase, putative 0.0121 0.0265 0.6107
Schistosoma mansoni apoptosis stimulating of P53 0.0022 0.0009 0.0009
Echinococcus granulosus netrin receptor unc 5 0.007 0.0133 0.0133
Entamoeba histolytica protein kinase domain containing protein 0.0185 0.0429 1
Brugia malayi serine/threonine protein kinase 6 0.0121 0.0265 0.0265
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus granulosus g protein coupled receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0003 0.0003
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0185 0.0429 0.0526
Trichomonas vaginalis AGC family protein kinase 0.0121 0.0265 0.3885
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0009 0.0009
Onchocerca volvulus 0.0042 0.0063 0.0178
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0064 0.0119 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0249 0.0249
Echinococcus granulosus twitchin 0.0205 0.048 0.048
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0085 0.0085
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0037 0.0537
Echinococcus multilocularis endophilin A3 0.0022 0.0009 0.0009
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0141 0.3137
Echinococcus multilocularis FL cytokine receptor 0.0064 0.0119 0.0119
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0032 0.0036 0.0036
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0005 0.0005
Plasmodium falciparum cysteine repeat modular protein 3 0.0039 0.0054 0.1915
Loa Loa (eye worm) hypothetical protein 0.0054 0.0093 0.0091
Entamoeba histolytica protein kinase, putative 0.0185 0.0429 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0129 0.0128
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis tyrosine protein kinase Abl 0.0284 0.0685 0.0685
Echinococcus granulosus SH2 domain containing protein 7 0.0032 0.0036 0.0036
Brugia malayi Immunoglobulin I-set domain containing protein 0.0106 0.0227 0.0227
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.1185 0.2999 0.3683
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0064 0.0119 0.0118
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Echinococcus multilocularis alpha 1A adrenergic receptor 0.002 0.0005 0.0005
Echinococcus granulosus cyclin dependent kinase 1 0.0093 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Brugia malayi jmjC domain containing protein 0.0066 0.0124 0.0124
Schistosoma mansoni ephrin receptor 0.0074 0.0144 0.0144
Echinococcus multilocularis tyrosine protein kinase csk 0.0064 0.0119 0.0119
Trichomonas vaginalis AGC family protein kinase 0.0121 0.0265 0.3885
Trypanosoma brucei fructose-1,6-bisphosphatase 0.3187 0.8143 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.002 0.0005 0.0005
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0042 0.0063 0.0062
Brugia malayi cell division control protein 2 homolog 0.0093 0.0193 0.0193
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0032 0.0036 0.0036
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0097 0.0202 0.4591
Echinococcus multilocularis lamin 0.003 0.003 0.003
Echinococcus multilocularis dual specificity 0.0185 0.0429 0.0429
Echinococcus multilocularis dro:myosuppressin receptor 0.002 0.0005 0.0005
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0125 0.0154
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.002 0.0024
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0064 0.0119 0.0119
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0037 0.1301
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Loa Loa (eye worm) cytochrome P450 0.0026 0.002 0.0018
Brugia malayi jmjC domain containing protein 0.0065 0.012 0.012
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Loa Loa (eye worm) TK protein kinase 0.0064 0.0119 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0042 0.0063 0.0063
Entamoeba histolytica tyrosin kinase, putative 0.0064 0.0119 0.2619
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0052 0.0088 0.0087
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0052 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0005 0.0005
Brugia malayi bone morphogenetic protein type 1 receptor 0.0064 0.0119 0.0119
Echinococcus multilocularis fmrfamide receptor 0.002 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0028 0.0025 0.0025
Echinococcus granulosus cyclin dependent kinase 5 0.0093 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0026 0.002 0.0754
Loa Loa (eye worm) hypothetical protein 0.0167 0.0383 0.0381
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0125 0.2762
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis lysine specific demethylase 5A 0.0065 0.012 0.012
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Entamoeba histolytica ankyrin repeat protein 0.0064 0.0119 0.2619
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Brugia malayi SH2 domain containing protein 0.0097 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0125 0.0125
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.018 0.0415 0.0415
Echinococcus granulosus Immunoglobulin 0.0054 0.0093 0.0093
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1756 0.4465 0.4465
Brugia malayi Serotonin receptor 0.002 0.0005 0.0005
Schistosoma mansoni peptide (allatostatin)-like receptor 0.002 0.0005 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Echinococcus multilocularis tyrosine protein kinase csk 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis raf serine:threonine protein kinase 0.0301 0.0728 0.0728
Brugia malayi GCC2 and GCC3 family protein 0.0039 0.0054 0.0054
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0022 0.0009 0.0008
Brugia malayi Protein kinase domain containing protein 0.0294 0.071 0.071
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Trypanosoma brucei conserved protein 0.0022 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0106 0.0227 0.0226
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0119 0.0258 0.8837
Schistosoma mansoni nephrin 0.0106 0.0227 0.0227
Echinococcus granulosus G protein coupled receptor 139 0.002 0.0005 0.0005
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0003 0.0003
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0093 0.0193 0.0237
Onchocerca volvulus 0.004 0.0055 0.0155
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0118 0.0257 0.0257
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0121 0.0265 0.6107
Onchocerca volvulus 0.0064 0.0119 0.035
Echinococcus granulosus geminin 0.0186 0.0432 0.0432
Brugia malayi Protein kinase domain containing protein 0.0097 0.0202 0.0202
Echinococcus granulosus Immunoglobulin 0.0154 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0026 0.002 0.0754
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.002 0.0005 0.0005
Entamoeba histolytica serine/threonine kinase, putative 0.0064 0.0119 0.2619
Loa Loa (eye worm) CYP4Cod1 0.0044 0.0067 0.0066
Echinococcus multilocularis tensin 0.0032 0.0036 0.0036
Echinococcus multilocularis titin 0.0042 0.0063 0.0063
Echinococcus granulosus neuropeptide receptor 0.002 0.0005 0.0005
Echinococcus granulosus SH2 domain containing adapter protein F 0.0032 0.0036 0.0036
Entamoeba histolytica protein kinase, putative 0.0126 0.0277 0.6387
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.0088 0.0088
Echinococcus multilocularis Immunoglobulin subtype 0.0054 0.0093 0.0093
Echinococcus granulosus endonuclease reverse transcriptase 0.0039 0.0054 0.0054
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0054 0.0093 0.0093
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0064 0.0119 0.2619
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0158 0.036 0.036
Loa Loa (eye worm) projectin 0.0052 0.0088 0.0087
Loa Loa (eye worm) AUR protein kinase 0.0121 0.0265 0.0264
Echinococcus granulosus protein kinase 0.0064 0.0119 0.0119
Schistosoma mansoni nephrin 0.0206 0.0484 0.0484
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0087 0.0087
Entamoeba histolytica tyrosin kinase, putative 0.0064 0.0119 0.2619
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0683 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0037 1
Echinococcus multilocularis serotonin receptor 0.0167 0.0383 0.0383
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0249 0.0306
Echinococcus granulosus natriuretic peptide receptor 1 0.0064 0.0119 0.0119
Trichomonas vaginalis p67phox protein, putative 0.0022 0.0009 0.0135
Onchocerca volvulus Glucosylceramidase homolog 0.0186 0.0432 0.1307
Echinococcus granulosus Immunoglobulin subtype 0.0054 0.0093 0.0093
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0064 0.0119 0.2619
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0054 0.0093 0.0093
Echinococcus granulosus neuropeptide receptor A26 0.002 0.0005 0.0005
Leishmania major protein kinase, putative 0.0064 0.0119 0.0146
Trypanosoma cruzi protein kinase, putative 0.0064 0.0119 0.0146
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0126 0.0126
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) RGC/RGC protein kinase 0.0068 0.0129 0.0128
Echinococcus multilocularis neuropeptide receptor 0.002 0.0005 0.0005
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Echinococcus multilocularis 0.0042 0.0063 0.0063
Trichomonas vaginalis neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative 0.0022 0.0009 0.0135
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0064 0.0119 0.2619
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0026 0.002 0.0754
Echinococcus granulosus lamin 0.003 0.003 0.003
Echinococcus multilocularis tyrosine kinase 0.0068 0.0129 0.0129
Plasmodium falciparum tyrosine kinase-like protein 0.0064 0.0119 0.4227
Echinococcus granulosus retinal guanylyl cyclase 2 0.0064 0.0119 0.0119
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Echinococcus granulosus tyrosine protein kinase Fyn 0.018 0.0415 0.0415
Echinococcus granulosus neuropeptide FF receptor 2 0.002 0.0005 0.0005
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0064 0.0119 0.035
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.002 0.0005 0.0005
Echinococcus granulosus alpha 1A adrenergic receptor 0.002 0.0005 0.0005
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.0261 0.0261
Plasmodium vivax cysteine repeat modular protein 2, putative 0.0039 0.0054 0.1915
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0261 0.5995
Echinococcus granulosus retinal guanylyl cyclase 2 0.0064 0.0119 0.0119
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0053 0.0053
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Echinococcus multilocularis Spectrin alpha actinin 0.0022 0.0009 0.0009
Echinococcus multilocularis RUN 0.0043 0.0065 0.0065
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0093 0.0193 0.0237
Echinococcus granulosus bloom syndrome protein 0.0023 0.0014 0.0014
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.14 0.3552 0.3552
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0023
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0052 0.0088 0.0087
Trichomonas vaginalis AGC family protein kinase 0.0121 0.0265 0.3885
Echinococcus granulosus tyrosine protein kinase shark 0.0097 0.0202 0.0202
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0026 0.002 0.0672
Entamoeba histolytica hypothetical protein 0.0064 0.0119 0.2619
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0005 0.0003
Echinococcus granulosus 7tm_1 domain containing protein 0.002 0.0005 0.0005
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0042 0.0063 0.0063
Echinococcus multilocularis cyclin dependent kinase 5 0.0093 0.0193 0.0193
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0054 0.1915
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0037 0.1406
Echinococcus multilocularis tensin 0.0032 0.0036 0.0036
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.018 0.0415 0.0415
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0202 0.0201
Echinococcus multilocularis SH2 domain containing protein 7 0.0032 0.0036 0.0036
Loa Loa (eye worm) MH2 domain-containing protein 0.0131 0.0291 0.029
Brugia malayi Immunoglobulin I-set domain containing protein 0.0107 0.0228 0.0228
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0005 0.0005
Onchocerca volvulus 0.0028 0.0025 0.0061
Loa Loa (eye worm) hypothetical protein 0.0072 0.0139 0.0137
Schistosoma mansoni hypothetical protein 0.0042 0.0063 0.0063
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0058 0.1163
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0026 0.002 0.0672
Brugia malayi STAT protein, DNA binding domain containing protein 0.0032 0.0036 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0282 0.0282
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0054 0.0093 0.0093
Schistosoma mansoni protein kinase 0.0073 0.0141 0.0141
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0087 0.2985
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0009 0.0011
Plasmodium vivax serine/threonine kinase-1, putative 0.0128 0.0282 1
Schistosoma mansoni slit 0.0042 0.0063 0.0063
Loa Loa (eye worm) TK/Met protein kinase 0.0064 0.0119 0.0118
Onchocerca volvulus Putative titin 0.0042 0.0063 0.0178
Loa Loa (eye worm) hypothetical protein 0.0054 0.0093 0.0091
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0058 0.0071
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0042 0.0063 0.0063
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0185 0.0429 0.0526
Echinococcus multilocularis mitogen activated protein kinase 0.0115 0.0249 0.0249
Schistosoma mansoni protein kinase 0.0064 0.0119 0.0119
Echinococcus granulosus 7TM GPCR rhodopsin 0.002 0.0005 0.0005
Echinococcus multilocularis hemicentin 1 0.0096 0.0202 0.0202
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Trypanosoma brucei cdc2-related kinase 1 0.0093 0.0193 0.0237
Entamoeba histolytica hypothetical protein 0.0064 0.0119 0.2619
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0026 0.002 0.0672
Echinococcus multilocularis transfer RNA-Thr 0.0064 0.0119 0.0119
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.0458 0.6706
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0093 0.0193 0.0193
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.003 0.003
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1458 0.3701 0.37
Loa Loa (eye worm) hypoxia-induced factor 1 0.0165 0.0379 0.0378
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0032 0.0036 0.0036
Echinococcus multilocularis allatostatin A receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Echinococcus multilocularis roundabout 2 0.0106 0.0227 0.0227
Echinococcus granulosus tyrosine kinase 0.0068 0.0129 0.0129
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0202 0.0201
Brugia malayi Cytochrome P450 family protein 0.0044 0.0067 0.0067
Echinococcus granulosus Spectrin alpha actinin 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0119 0.026 0.0259
Echinococcus multilocularis g protein coupled receptor 0.002 0.0005 0.0005
Trypanosoma brucei protein kinase, putative 0.0115 0.0249 0.0306
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.002 0.0005 0.0005
Brugia malayi Doublecortin family protein 0.0043 0.0065 0.0065
Schistosoma mansoni hypothetical protein 0.002 0.0005 0.0005
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0032 0.0036 0.0035
Onchocerca volvulus 0.0042 0.0063 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0119 0.1744
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0041 0.0058 0.1167
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0064 0.0119 0.0146
Echinococcus multilocularis 0.0032 0.0036 0.0036
Loa Loa (eye worm) RGC/RGC protein kinase 0.0064 0.0119 0.0118
Schistosoma mansoni protein kinase 0.0064 0.0119 0.0119
Brugia malayi Peripheral plasma membrane protein CASK 0.0022 0.0009 0.0009
Onchocerca volvulus 0.0064 0.0119 0.035
Echinococcus granulosus metabotropic glutamate receptor 5 0.005 0.0082 0.0082
Entamoeba histolytica SH2 domain containing protein 0.0032 0.0036 0.0649
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0128 0.0282 0.0346
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0064 0.0119 0.0119
Brugia malayi ephrin receptor 1 precursor 0.0142 0.0317 0.0317
Brugia malayi Variant SH3 domain containing protein 0.0054 0.0092 0.0092
Echinococcus multilocularis tyrosine protein kinase csk 0.0064 0.0119 0.0119
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0064 0.0119 0.0119
Entamoeba histolytica hypothetical protein 0.0064 0.0119 0.2619
Echinococcus multilocularis intersectin 2 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0125 0.0125
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Loa Loa (eye worm) disorganized muscle protein 1 0.0042 0.0063 0.0062
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0261 0.0261
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0005 0.0005
Schistosoma mansoni cell adhesion molecule 0.0106 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0106 0.0227 0.0227
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0065 0.0065
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0064 0.0119 0.0146
Echinococcus multilocularis activated cdc42 kinase 1 0.0064 0.0119 0.0119
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0026 0.002 0.0672
Loa Loa (eye worm) hypothetical protein 0.0097 0.0202 0.0201
Echinococcus multilocularis protein kinase 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Trypanosoma brucei sedoheptulose-1,7-bisphosphatase 0.1185 0.2999 0.3683
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0115 0.0248 0.0247
Schistosoma mansoni tyrosine kinase 0.1391 0.3527 0.3527
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0135
Brugia malayi Immunoglobulin I-set domain containing protein 0.007 0.0133 0.0133
Schistosoma mansoni netrin receptor unc5 0.007 0.0133 0.0133
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0128 0.0282 0.0346
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0009 0.0009
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0052 0.0088 0.0087
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0432 0.6328
Echinococcus multilocularis g protein coupled receptor 0.002 0.0005 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.0458 0.6706
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.002 0.0005 0.0005
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.002 0.0005 0.0005
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0124 0.0124
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Onchocerca volvulus 0.0064 0.0119 0.035
Echinococcus granulosus g-protein coupled receptor 0.002 0.0005 0.0005
Brugia malayi GCC2 and GCC3 family protein 0.0039 0.0054 0.0054
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0026 0.002 0.0672
Trichomonas vaginalis TK family protein kinase 0.0064 0.0119 0.1744
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0058 1
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0097 0.0202 0.0202
Entamoeba histolytica hypothetical protein 0.0064 0.0119 0.2619
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0005 0.0005
Echinococcus multilocularis tyrosine kinase 0.0097 0.0202 0.0202
Schistosoma mansoni nck2/grb4 0.0054 0.0092 0.0092
Echinococcus granulosus orexin receptor type 2 0.002 0.0005 0.0005
Loa Loa (eye worm) TK/ABL protein kinase 0.0532 0.132 0.1318
Schistosoma mansoni tyrosine kinase 0.0097 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0096 0.0202 0.0202
Echinococcus granulosus raf serine:threonine protein kinase 0.0301 0.0728 0.0728
Brugia malayi phosphofructokinase 0.0119 0.0261 0.0261
Plasmodium falciparum cysteine repeat modular protein 4 0.0039 0.0054 0.1915
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.004 0.0058 0.0058
Schistosoma mansoni cytochrome P450 0.0026 0.002 0.002
Brugia malayi Protein kinase domain containing protein 0.0128 0.0282 0.0282
Loa Loa (eye worm) hypothetical protein 0.0164 0.0374 0.0373
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0106 0.0227 0.0227
Echinococcus multilocularis signal transduction protein lnk realted 0.0032 0.0036 0.0036
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.0261 1
Brugia malayi Spectrin alpha chain 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0096 0.0202 0.02
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0026 0.002 0.0754
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0064 0.0119 0.2619
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0026 0.002 0.0754
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0035 0.0034
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0005 0.0005
Echinococcus granulosus fch and double sh3 domains protein 2 0.0022 0.0009 0.0009
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0064 0.0119 0.1744
Toxoplasma gondii sedoheptulose-1,7-bisphosphatase 0.1185 0.2999 0.3683
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.002 0.0005 0.0005
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0014 0.0014
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Schistosoma mansoni tyrosine kinase 0.2148 0.5472 0.5472
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0121 0.0265 0.0265
Echinococcus granulosus epidermal growth factor receptor 0.2148 0.5472 0.5472
Echinococcus granulosus neuroglian 0.0196 0.0458 0.0458
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Brugia malayi Protein kinase domain containing protein 0.0097 0.0202 0.0202
Schistosoma mansoni cell adhesion molecule 0.0106 0.0227 0.0227
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0063 0.0063
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0261 0.3817
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0208 0.0488 0.0488
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0022 0.0009 0.0009
Schistosoma mansoni tensin-related 0.0032 0.0036 0.0036
Echinococcus multilocularis fmrfamide receptor 0.002 0.0005 0.0005
Brugia malayi Prion-like- 0.0042 0.0063 0.0063
Brugia malayi Tyrosine-protein kinase PR2 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0039 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Loa Loa (eye worm) RhoGAP domain-containing protein 0.004 0.0058 0.0057
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0065 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0164 0.0374 0.0373
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis SH2 motif 0.0032 0.0036 0.0036
Brugia malayi cytochrome P450 0.0026 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0037 0.0045
Brugia malayi neuropeptide F receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0176 0.0407 0.0406
Schistosoma mansoni Dab2-interacting protein-like 0.0022 0.0009 0.0009
Echinococcus multilocularis cyclin dependent kinase 1 0.0093 0.0193 0.0193
Loa Loa (eye worm) SRC-1 0.018 0.0415 0.0414
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0118 0.0257 0.0257
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.002 0.0005 0.0005
Onchocerca volvulus 0.0032 0.0036 0.0097
Entamoeba histolytica hypothetical protein 0.0064 0.0119 0.2619
Onchocerca volvulus 0.0022 0.0009 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0135
Echinococcus granulosus growth factor receptor bound protein 2 0.0054 0.0092 0.0092
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0005 0.0005
Brugia malayi GCC2 and GCC3 family protein 0.0039 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Toxoplasma gondii protein kinase domain-containing protein 0.0064 0.0119 0.0146
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0064 0.0119 0.0118
Loa Loa (eye worm) thyroid receptor interactor 0.0022 0.0009 0.0008
Schistosoma mansoni loxhd1 0.0043 0.0065 0.0065
Giardia lamblia Kinase, CMGC CDK 0.0093 0.0193 0.6862
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0284 0.0683 0.0682
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0064 0.0119 0.0118
Brugia malayi fructose-1,6-bisphosphatase 0.3187 0.8143 0.8143
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0063 0.0063
Entamoeba histolytica protein kinase, putative 0.0047 0.0076 0.1584
Echinococcus multilocularis roundabout 2 0.026 0.0622 0.0622
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0202 0.0201
Brugia malayi bHLH-PAS transcription factor 0.004 0.0055 0.0055
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1294 0.328 0.3279
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0203 0.0474 0.0473
Brugia malayi SH3 domain containing protein 0.0022 0.0009 0.0009
Brugia malayi Cytochrome P450 family protein 0.0064 0.0119 0.0119
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0064 0.0119 0.2619
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0432 0.6328
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Brugia malayi hypothetical protein 0.0043 0.0065 0.0065
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0261 0.3817
Loa Loa (eye worm) phosphofructokinase 0.0119 0.0261 0.0259
Leishmania major protein kinase, putative 0.0121 0.0265 0.0326
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0064 0.0119 0.0118
Onchocerca volvulus 0.0064 0.0119 0.035
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0891 0.2243 0.2243
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0005 0.0005
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0034 0.0041 0.0041
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0064 0.0119 0.0119
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0005 0.0005
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0054 0.0092 0.0091
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0005 0.0005
Echinococcus granulosus neuropeptide s receptor 0.002 0.0005 0.0005
Echinococcus granulosus tyrosine kinase 0.0158 0.036 0.036
Echinococcus multilocularis endonuclease reverse transcriptase 0.0039 0.0054 0.0054
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0026 0.002 0.0672
Loa Loa (eye worm) TK/ALK protein kinase 0.0294 0.071 0.0709
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0202 0.0201
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0032 0.0036 0.0036
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0054 0.0093 0.0093
Echinococcus granulosus tyrosine protein kinase Src42A 0.018 0.0415 0.0415
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0202 0.0201
Echinococcus multilocularis SH2 motif 0.0032 0.0036 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0121 0.0265 0.6107
Giardia lamblia Hypothetical protein 0.0039 0.0054 0.1915
Echinococcus multilocularis heat shock protein 70 0.0064 0.0119 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0119 0.0258 0.8753
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0054 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Brugia malayi Immunoglobulin I-set domain containing protein 0.1458 0.3701 0.3701
Loa Loa (eye worm) p53BP2 0.0022 0.0009 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0054 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0052 0.0088 0.0087
Entamoeba histolytica hypothetical protein, conserved 0.0064 0.0119 0.2619
Entamoeba histolytica cysteine-rich surface protein, putative 0.0039 0.0054 0.1066
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0032 0.0036 0.0036
Echinococcus granulosus titin 0.0061 0.011 0.011
Loa Loa (eye worm) serine/threonine protein kinase 0.0064 0.0119 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Echinococcus granulosus cpg binding protein 0.0033 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Leishmania major protein kinase, putative 0.0128 0.0282 0.0346
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.0022 0.0009 0.0009
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0115 0.0249 0.0306
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0064 0.0118 0.0118
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.002 0.0005 0.0003
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.002 0.0005 0.0005
Brugia malayi SH2 domain containing protein 0.0032 0.0036 0.0036
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0128 0.0282 0.0346
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Schistosoma mansoni aryl hydrocarbon receptor 0.0053 0.0091 0.0091
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.3187 0.8143 1
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Schistosoma mansoni neuropeptide receptor 0.002 0.0005 0.0005
Schistosoma mansoni amine GPCR 0.002 0.0005 0.0005
Echinococcus multilocularis titin 0.0042 0.0063 0.0063
Schistosoma mansoni vesicular amine transporter 0.0154 0.0349 0.0349
Schistosoma mansoni rab6-interacting 0.0043 0.0065 0.0065
Schistosoma mansoni hypothetical protein 0.0186 0.0432 0.0432
Schistosoma mansoni titin 0.0096 0.0202 0.0202
Toxoplasma gondii protein kinase 0.0064 0.0119 0.0146
Brugia malayi Immunoglobulin I-set domain containing protein 0.0106 0.0227 0.0227
Plasmodium vivax tyrosine kinase-like protein, putative 0.0064 0.0119 0.4227
Brugia malayi Dopamine receptor protein 1 0.002 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.1391 0.3527 0.3527
Echinococcus multilocularis protein KINase family member (kin 25) 0.0064 0.0119 0.0119
Schistosoma mansoni sorbin 0.0022 0.0009 0.0009
Brugia malayi hypothetical protein 0.0179 0.0415 0.0415
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Loa Loa (eye worm) hypothetical protein 0.0179 0.0415 0.0413
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Brugia malayi Tensin 0.0032 0.0036 0.0036
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0073 0.0141 0.0173
Brugia malayi Melatonin receptor type 1A 0.002 0.0005 0.0005
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.002 0.0005 0.0005
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0026 0.002 0.0754
Loa Loa (eye worm) hypothetical protein 0.0043 0.0065 0.0064
Brugia malayi basement membrane proteoglycan 0.0054 0.0093 0.0093
Trypanosoma cruzi paraflagellar rod protein 5, putative 0.0022 0.0009 0.0011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0054 0.0093 0.0093
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0132 0.0292 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Onchocerca volvulus 0.0032 0.0036 0.0097
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0005 0.0005
Loa Loa (eye worm) melatonin receptor type 1A 0.002 0.0005 0.0003
Toxoplasma gondii aurora kinase 0.0121 0.0265 0.0326
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0005 0.0005
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0022 0.0011 0.0014
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0064 0.0119 0.0119
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0005 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.0022 0.0009 0.0009
Loa Loa (eye worm) raf kinase 0.0237 0.0562 0.0561
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0026 0.002 0.0754
Brugia malayi Prion-like- 0.0042 0.0063 0.0063
Echinococcus granulosus expressed protein 0.0022 0.0009 0.0009
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0064 0.0119 0.0119
Onchocerca volvulus 0.0097 0.0202 0.0603
Onchocerca volvulus 0.0042 0.0063 0.0178
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0106 0.0227 0.0227
Onchocerca volvulus 0.0097 0.0202 0.0603
Onchocerca volvulus 0.0097 0.0202 0.0603
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Onchocerca volvulus Peroxidasin homolog 0.0042 0.0063 0.0178
Brugia malayi Protein kinase domain containing protein 0.0093 0.0193 0.0193
Echinococcus multilocularis tyrosine protein kinase Fyn 0.018 0.0415 0.0415
Schistosoma mansoni protein kinase 0.0064 0.0119 0.0119
Brugia malayi protein unc-22 0.0061 0.011 0.011
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Loa Loa (eye worm) TK protein kinase 0.0064 0.0119 0.0118
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0065 0.231
Brugia malayi G protein-coupled receptor F59B2.13 0.002 0.0005 0.0005
Brugia malayi Dopamine receptor 0.002 0.0005 0.0005
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0064 0.0119 0.0119
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0107 0.0228 0.0228
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0432 0.6328
Echinococcus multilocularis geminin 0.0186 0.0432 0.0432
Brugia malayi Protein kinase domain containing protein 0.1294 0.328 0.328
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0032 0.0036 0.0036
Entamoeba histolytica hypothetical protein 0.0064 0.0119 0.2619
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0064 0.0119 0.2619
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0014 0.0014
Onchocerca volvulus 0.003 0.003 0.0077
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0042 0.0063 0.0063
Brugia malayi Peroxidasin 0.0096 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0023
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0527 0.1307 0.1605
Echinococcus granulosus intersectin 2 0.0022 0.0009 0.0009
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0261 0.032
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0064 0.0119 0.0119
Entamoeba histolytica hypothetical protein 0.0039 0.0054 0.1066
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Onchocerca volvulus 0.0052 0.0088 0.0255
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0064 0.0119 0.0118
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0527 0.1307 0.1605
Onchocerca volvulus 0.0042 0.0063 0.0178
Echinococcus granulosus hypothetical protein 0.0032 0.0036 0.0036
Schistosoma mansoni rab6-interacting 0.0043 0.0065 0.0065
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0032 0.0036 0.0036
Brugia malayi Immunoglobulin I-set domain containing protein 0.0096 0.0202 0.0202
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0065 0.0065
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Onchocerca volvulus 0.0022 0.0009 0.0014
Schistosoma mansoni run and tbc1 domain containing 0.0022 0.0009 0.0009
Trypanosoma brucei aurora B kinase 0.0121 0.0265 0.0326
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0261 0.0259
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Brugia malayi Variant SH3 domain containing protein 0.0032 0.0036 0.0036
Schistosoma mansoni tyrosine kinase 0.0118 0.0257 0.0257
Schistosoma mansoni protein kinase 0.0073 0.0141 0.0141
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Brugia malayi Animal haem peroxidase family protein 0.0042 0.0063 0.0063
Echinococcus multilocularis 0.0119 0.026 0.026
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0044 0.0067 0.2575
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0037 0.0537
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0005 0.0005
Brugia malayi ORL1-like opioid receptor 0.002 0.0005 0.0005
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0037 0.0537
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Onchocerca volvulus 0.0068 0.0129 0.038
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0005 0.0005
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0093 0.0193 0.0192
Schistosoma mansoni tensin 0.0032 0.0036 0.0036
Echinococcus multilocularis tyrosine protein kinase Srms 0.0158 0.036 0.036
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0116 0.0116
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.018 0.0415 0.0415
Brugia malayi Serotonin receptor 0.002 0.0005 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0096 0.0202 0.0202
Plasmodium vivax protein kinase Crk2 0.0093 0.0193 0.6862
Entamoeba histolytica protein kinase , putative 0.0121 0.0265 0.6107
Echinococcus granulosus contactin 0.0106 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.0096 0.0202 0.02
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0054 0.0093 0.0093
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0014 0.0205
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0087 0.3097
Echinococcus multilocularis orexin receptor type 2 0.002 0.0005 0.0005
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Brugia malayi Tyrosine-protein kinase abl-1 0.0284 0.0685 0.0685
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0119 0.0118
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0064 0.0119 0.0118
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0022 0.0009 0.0009
Trypanosoma brucei trypanothione reductase 0.0052 0.0087 0.0107
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0042 0.0063 0.0063
Mycobacterium tuberculosis Probable reductase 0.0119 0.0258 0.8837
Echinococcus granulosus lamin dm0 0.003 0.003 0.003
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0026 0.002 0.0672
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0054 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0064 0.0119 0.0118
Brugia malayi SH2 domain containing protein 0.0032 0.0036 0.0036
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.002 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0026 0.002 0.0672
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Echinococcus multilocularis neuropeptide receptor 0.002 0.0005 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0093 0.0193 0.2831
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0032 0.0036 0.0036
Toxoplasma gondii fructose-bisphospatase I 0.1185 0.2999 0.3683
Schistosoma mansoni basigin related 0.0054 0.0093 0.0093
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0026 0.002 0.0754
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0005 0.0005
Brugia malayi basement membrane proteoglycan precursor 0.0054 0.0093 0.0093
Schistosoma mansoni neuropeptide receptor 0.002 0.0005 0.0005
Echinococcus granulosus tyrosine protein kinase Fyn 0.018 0.0415 0.0415
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Schistosoma mansoni serine/threonine RGC 0.0064 0.0119 0.0119
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0119 0.0258 0.8837
Brugia malayi RE15519p 0.002 0.0005 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Leishmania major protein kinase, putative 0.0128 0.0282 0.0346
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Echinococcus granulosus leucine rich repeat containing protein 4 0.0042 0.0063 0.0063
Brugia malayi Immunoglobulin domain containing protein 0.0054 0.0093 0.0093
Loa Loa (eye worm) AUR protein kinase 0.0121 0.0265 0.0264
Schistosoma mansoni tyrosine kinase 0.0118 0.0257 0.0257
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Onchocerca volvulus 0.003 0.0031 0.008
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Leishmania major cytochrome p450-like protein 0.0044 0.0067 0.0082
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0022 0.0011 0.0014
Plasmodium falciparum protein kinase 5 0.0093 0.0193 0.6862
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0058 0.0071
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0125 0.0125
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0005 0.0005
Schistosoma mansoni roundabout 0.0096 0.0202 0.0202
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0429 0.0429
Brugia malayi Immunoglobulin I-set domain containing protein 0.0106 0.0227 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0135
Entamoeba histolytica receptor protein kinase, putative 0.0064 0.0119 0.2619
Toxoplasma gondii thioredoxin reductase 0.0052 0.0087 0.0107
Trypanosoma cruzi cdc2-related kinase 1 0.0093 0.0193 0.0237
Loa Loa (eye worm) inositol-1 0.0041 0.0058 0.0057
Entamoeba histolytica cell division protein kinase 2, putative 0.0093 0.0193 0.4389
Loa Loa (eye worm) hypothetical protein 0.0064 0.0119 0.0118
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0058 0.2226
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Echinococcus granulosus src region 0.0022 0.0009 0.0009
Brugia malayi Immunoglobulin I-set domain containing protein 0.0061 0.011 0.011
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.0261 0.884
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Echinococcus granulosus endophilin A3 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0058 0.0071
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0132 0.0292 1
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Schistosoma mansoni cell adhesion molecule 0.0054 0.0093 0.0093
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0198 0.0463 0.0462
Schistosoma mansoni dynamin-associated protein 0.0022 0.0009 0.0009
Onchocerca volvulus 0.0032 0.0036 0.0097
Loa Loa (eye worm) TK/ACK protein kinase 0.0064 0.0119 0.0118
Loa Loa (eye worm) TK/CSK protein kinase 0.0064 0.0119 0.0118
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0119 0.0119
Echinococcus multilocularis down syndrome cell adhesion 0.0042 0.0063 0.0063
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0007 0.0237
Schistosoma mansoni cpg binding protein 0.0033 0.0039 0.0039
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0132 0.0292 1
Brugia malayi glutathione reductase 0.0052 0.0087 0.0087
Schistosoma mansoni titin 0.0042 0.0063 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Schistosoma mansoni hypothetical protein 0.0042 0.0063 0.0063
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0064 0.0119 0.0119
Entamoeba histolytica protein kinase domain containing protein 0.0121 0.0265 0.6107
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0054 0.0092 0.0092
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Brugia malayi metabotropic glutamate receptor type 2 0.002 0.0005 0.0005
Echinococcus multilocularis epidermal growth factor receptor 0.2148 0.5472 0.5472
Echinococcus multilocularis growth factor receptor bound protein 2 0.0054 0.0092 0.0092
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Schistosoma mansoni opsin-like receptor 0.002 0.0005 0.0005
Onchocerca volvulus Tyrosine kinase homolog 0.1293 0.3275 1
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0064 0.0119 0.1744
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0115 0.0249 0.0306
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0064 0.0119 0.0119
Schistosoma mansoni neuroglian 0.0106 0.0227 0.0227
Trichomonas vaginalis AGC family protein kinase 0.0121 0.0265 0.3885
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0115 0.0249 0.0306
Loa Loa (eye worm) cytochrome P450 family protein 0.0044 0.0067 0.0066
Echinococcus granulosus ephrin type A receptor 4 A 0.0267 0.064 0.064
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0119 0.0118
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0009 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0026 0.002 0.0672
Schistosoma mansoni lamin 0.003 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0054 0.0092 0.0091
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0073 0.0141 0.0173
Echinococcus multilocularis receptor type guanylyl cyclase 0.0068 0.0129 0.0129
Brugia malayi C-terminal src kinase protein 1 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.025 0.0597 0.0596
Brugia malayi Fes/CIP4 homology domain containing protein 0.0022 0.0009 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0026 0.002 0.0672
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0064 0.0119 0.0119
Entamoeba histolytica hypothetical protein 0.0064 0.0119 0.2619
Brugia malayi 6-phosphofructokinase 0.0119 0.0261 0.0261
Echinococcus granulosus RUN 0.0043 0.0065 0.0065
Schistosoma mansoni hypothetical protein 0.0039 0.0054 0.0054
Echinococcus multilocularis insulin receptor 0.1391 0.3527 0.3527
Schistosoma mansoni netrin receptor unc5 0.0054 0.0093 0.0093
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.0261 0.8918
Schistosoma mansoni lipoxygenase 0.0112 0.0242 0.0242
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0064 0.0119 0.1744
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Giardia lamblia Protein 21.1 0.0064 0.0119 0.4227
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0065 0.231
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0125 0.0154
Echinococcus multilocularis cpg binding protein 0.0033 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Schistosoma mansoni tyrosine kinase 0.0068 0.0129 0.0129
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.018 0.0415 0.0415
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0093 0.0193 0.0192
Schistosoma mansoni vav2 0.004 0.0058 0.0058
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0107 0.0228 0.0228
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0047 0.1007
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0042 0.0063 0.0062
Echinococcus multilocularis musashi 0.003 0.003 0.003
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Brugia malayi hypothetical protein 0.0243 0.0579 0.0579
Brugia malayi Protein kinase domain containing protein 0.0136 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0064 0.0119 0.0119
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.0088 0.0088
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Entamoeba histolytica cysteine surface protein, putative 0.0064 0.0119 0.2619
Loa Loa (eye worm) hypothetical protein 0.0064 0.0119 0.0118
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.004 0.0058 0.0058
Schistosoma mansoni protein kinase 0.0064 0.0119 0.0119
Echinococcus multilocularis tyrosine protein kinase Blk 0.0158 0.036 0.036
Echinococcus multilocularis Immunoglobulin 0.0154 0.0349 0.0349
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0055 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0135
Echinococcus granulosus dnaJ subfamily B 0.0449 0.1109 0.1109
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0052 0.0088 0.0087
Schistosoma mansoni tyrosine protein kinase 0.0064 0.0119 0.0119
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0261 0.5995
Brugia malayi hypoxia-induced factor 1 0.0165 0.0379 0.0379
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0064 0.0119 0.0146
Loa Loa (eye worm) hypothetical protein 0.0096 0.0202 0.02
Echinococcus granulosus tachykinin peptides receptor 99D 0.002 0.0005 0.0005
Echinococcus granulosus roundabout 2 0.026 0.0622 0.0622
Schistosoma mansoni hypothetical protein 0.0026 0.002 0.002
Schistosoma mansoni septate junction protein 0.0054 0.0093 0.0093
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0026 0.002 0.0672
Echinococcus granulosus neuroglian 0.0106 0.0227 0.0227
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.0088 0.0088
Entamoeba histolytica protein kinase, putative 0.0064 0.0119 0.2619
Schistosoma mansoni hypothetical protein 0.0022 0.0009 0.0009
Schistosoma mansoni metabotropic glutamate receptor 0.0034 0.0041 0.0041
Brugia malayi SH2 domain containing protein 0.0032 0.0036 0.0036
Echinococcus granulosus protein tyrosine kinase 0.0064 0.0119 0.0119
Entamoeba histolytica protein kinase, putative 0.0185 0.0429 1
Echinococcus multilocularis N chimaerin 0.004 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0064 0.0119 0.0118
Entamoeba histolytica tyrosine kinase, putative 0.0064 0.0119 0.2619
Echinococcus granulosus mitogen activated protein kinase 14 0.0527 0.1307 0.1307
Schistosoma mansoni hypothetical protein 0.0043 0.0065 0.0065
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.019 0.0443 0.0443
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Entamoeba histolytica serine/threonine kinase, putative 0.0064 0.0119 0.2619
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0065 0.012 0.012
Entamoeba histolytica hypothetical protein 0.0039 0.0054 0.1066
Trypanosoma brucei cdc2-related kinase 3 0.0093 0.0193 0.0237
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0064 0.0119 0.2619
Brugia malayi Protein kinase domain containing protein 0.0185 0.0429 0.0429
Echinococcus granulosus low density lipoprotein receptor ldl 0.0054 0.0093 0.0093
Leishmania major protein kinase, putative 0.0022 0.0011 0.0014
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Echinococcus multilocularis metabotropic glutamate receptor 5 0.005 0.0082 0.0082
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0026 0.002 0.0754
Echinococcus multilocularis titin 0.0061 0.011 0.011
Loa Loa (eye worm) TK/FER protein kinase 0.0064 0.0119 0.0118
Onchocerca volvulus 0.0064 0.0119 0.035
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0073 0.0141 0.0173
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0046 0.0072 0.0072
Echinococcus multilocularis activin receptor type 0.0073 0.0141 0.0141
Echinococcus granulosus tyrosine protein kinase otk 0.0096 0.0202 0.0202
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Loa Loa (eye worm) hypothetical protein 0.0032 0.0036 0.0035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0005 0.0005
Trichomonas vaginalis STE family protein kinase 0.0064 0.0119 0.1744
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0022 0.0011 0.0014
Brugia malayi hypothetical protein 0.002 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0063 0.0063
Entamoeba histolytica tyrosin kinase, putative 0.0064 0.0119 0.2619
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Loa Loa (eye worm) TK protein kinase 0.0158 0.036 0.0359
Trypanosoma cruzi cdc2-related kinase 3 0.0093 0.0193 0.0237
Brugia malayi Tachykinin-like peptides receptor 99D 0.002 0.0005 0.0005
Schistosoma mansoni tyrosine kinase 0.2084 0.5307 0.5307
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0032 0.0036 0.0036
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0121 0.0265 0.0265
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0063 0.0063
Echinococcus granulosus sex peptide receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0003
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0064 0.0119 0.2619
Onchocerca volvulus 0.0097 0.0202 0.0603
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Brugia malayi hypothetical protein 0.0043 0.0065 0.0065
Schistosoma mansoni neuropeptide receptor 0.002 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0064 0.0119 0.2619
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Loa Loa (eye worm) hypothetical protein 0.005 0.0082 0.0081
Echinococcus granulosus tyrosine kinase 0.0097 0.0202 0.0202
Schistosoma mansoni tyrosine kinase 0.2084 0.5307 0.5307
Echinococcus multilocularis nostrin 0.0022 0.0009 0.0009
Leishmania major cytochrome p450-like protein 0.0026 0.002 0.0024
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.0022 0.0009 0.0009
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0096 0.0202 0.02
Giardia lamblia CEGP1 protein 0.0039 0.0054 0.1915
Echinococcus granulosus tyrosine protein kinase Blk 0.0158 0.036 0.036
Loa Loa (eye worm) SH2 domain-containing protein 0.0032 0.0036 0.0035
Schistosoma mansoni hypothetical protein 0.0032 0.0036 0.0036
Leishmania major hypothetical protein, conserved 0.0022 0.0009 0.0011
Onchocerca volvulus 0.0164 0.0374 0.113
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0064 0.0119 0.0118
Echinococcus multilocularis biogenic amine (5HT) receptor 0.002 0.0005 0.0005
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0064 0.0119 0.0119
Schistosoma mansoni cell adhesion molecule 0.0054 0.0093 0.0093
Echinococcus multilocularis protein kinase 0.0064 0.0119 0.0119
Schistosoma mansoni hypothetical protein 0.0028 0.0025 0.0025
Echinococcus granulosus tyrosine protein kinase csk 0.0064 0.0119 0.0119
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0119 0.0119
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0128 0.0282 0.0346
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0053 0.0053
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0005 0.0005
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0063 0.0116 0.3959
Schistosoma mansoni titin 0.0042 0.0063 0.0063
Trypanosoma cruzi protein kinase, putative 0.0064 0.0119 0.0146
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0185 0.0429 0.0526
Echinococcus multilocularis sex peptide receptor 0.002 0.0005 0.0005
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0154 0.0349 0.0349
Brugia malayi Immunoglobulin I-set domain containing protein 0.0096 0.0202 0.0202
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.011 0.011
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0064 0.0119 0.2619
Brugia malayi G-protein coupled receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0154 0.0349 0.0349
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0064 0.0119 0.0119
Schistosoma mansoni cell adhesion molecule 0.0052 0.0088 0.0088
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0125 0.0154
Loa Loa (eye worm) hypothetical protein 0.0208 0.0488 0.0487
Echinococcus granulosus defective proboscis extension response 0.0154 0.0349 0.0349
Echinococcus granulosus activated cdc42 kinase 1 0.0064 0.0119 0.0119
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.0261 1
Echinococcus multilocularis protein tyrosine kinase 0.0064 0.0119 0.0119
Loa Loa (eye worm) protein kinase domain-containing protein 0.0064 0.0119 0.0118
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0005 0.0005
Loa Loa (eye worm) TK/FAK protein kinase 0.0064 0.0119 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Trypanosoma cruzi cytochrome P450, putative 0.0044 0.0067 0.0082
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0125 0.0125
Schistosoma mansoni tyrosine kinase 0.0064 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0042 0.0063 0.0062
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0026 0.002 0.0672
Echinococcus multilocularis titin 0.0042 0.0063 0.0063
Echinococcus granulosus roundabout 2 0.0106 0.0227 0.0227
Schistosoma mansoni cell adhesion molecule 0.0052 0.0088 0.0088
Onchocerca volvulus 0.0043 0.0065 0.0185
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.0261 0.0261
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.0088 0.0088
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0005 0.0005
Brugia malayi Immunoglobulin domain containing protein 0.0054 0.0093 0.0093
Brugia malayi Protein kinase domain containing protein 0.0064 0.0119 0.0119
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0119 0.2619
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0026 0.002 0.0754
Trichomonas vaginalis TKL family protein kinase 0.0064 0.0119 0.1744
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0119 0.0258 0.8837

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 6.82 Binding affinity to adrenergic alpha1A receptor (unknown origin) ChEMBL. No reference
Ki (binding) = 0.41 nM Binding affinity to the adrenergic receptor alpha-1D of rat aorta ChEMBL. 15055991
Ki (binding) = 0.41 nM Binding affinity to the adrenergic receptor alpha-1D of rat aorta ChEMBL. 15055991
Ki (binding) = 13.11 nM Binding affinity constant against alpha-1B adrenergic receptor of guinea pig spleen ChEMBL. 15055991
Ki (binding) = 13.11 nM Binding affinity constant against alpha-1B adrenergic receptor of guinea pig spleen ChEMBL. 15055991
Ki (binding) = 149.344 nM Binding affinity to adrenergic alpha1A receptor (unknown origin) ChEMBL. No reference
Ki (binding) = 186.68 nM In vitro binding affinity towards alpha-1A adrenergic receptor through displacement of [3H]-prazosin in epididymal rat vas deferens. ChEMBL. 15055991
Ki (binding) = 186.68 nM In vitro binding affinity towards alpha-1A adrenergic receptor through displacement of [3H]-prazosin in epididymal rat vas deferens. ChEMBL. 15055991
Ki (binding) = 206.96 nM Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]-8-OH-DPAT) as radioligand ChEMBL. 15055991
Ki (binding) = 206.96 nM Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]-8-OH-DPAT) as radioligand ChEMBL. 15055991

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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