Detailed information for compound 1035245

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 527.397 | Formula: C25H26IN3O2
  • H donors: 1 H acceptors: 3 LogP: 4.61 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(c1cnc2c3c1cccc3c1c(C2=O)cccc1)NCC[N+]1(C)CCCCC1.[I-]
  • InChi: 1S/C25H25N3O2.HI/c1-28(13-5-2-6-14-28)15-12-26-25(30)21-16-27-23-22-18(10-7-11-19(21)22)17-8-3-4-9-20(17)24(23)29;/h3-4,7-11,16H,2,5-6,12-15H2,1H3;1H
  • InChiKey: VFCJYEKCSSECER-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Electrophorus electricus Acetylcholinesterase Starlite/ChEMBL References
Equus caballus Cholinesterase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus carboxylesterase 5A Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma japonicum Acetylcholinesterase 1 precursor, putative Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) acetylcholinesterase 1 Get druggable targets OG5_126875 All targets in OG5_126875
Brugia malayi Carboxylesterase family protein Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma japonicum ko:K01049 acetylcholinesterase [EC3.1.1.7], putative Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) carboxylesterase Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis carboxylesterase 5A Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Brugia malayi Carboxylesterase family protein Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus BC026374 protein S09 family Acetylcholinesterase   633 aa 690 aa 31.7 %
Onchocerca volvulus Molybdopterin synthase catalytic subunit homolog Acetylcholinesterase   633 aa 576 aa 28.8 %
Brugia malayi Carboxylesterase family protein Acetylcholinesterase   633 aa 517 aa 25.1 %
Onchocerca volvulus Putative nuclear protein Cholinesterase   574 aa 572 aa 40.9 %
Brugia malayi Carboxylesterase family protein Acetylcholinesterase   633 aa 620 aa 28.4 %
Onchocerca volvulus Galectin homolog Cholinesterase   574 aa 531 aa 39.7 %
Onchocerca volvulus Acetylcholinesterase   633 aa 648 aa 25.3 %
Loa Loa (eye worm) hypothetical protein Acetylcholinesterase   633 aa 597 aa 25.1 %
Onchocerca volvulus Cholinesterase   574 aa 578 aa 25.3 %
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) Acetylcholinesterase   633 aa 622 aa 24.9 %
Schistosoma japonicum ko:K01050 cholinesterase [EC3.1.1.8], putative Cholinesterase   574 aa 577 aa 36.9 %
Schistosoma mansoni gliotactin Cholinesterase   574 aa 587 aa 27.9 %
Onchocerca volvulus Cholinesterase   574 aa 551 aa 29.9 %
Echinococcus multilocularis BC026374 protein (S09 family) Acetylcholinesterase   633 aa 690 aa 32.3 %
Echinococcus granulosus neuroligin Cholinesterase   574 aa 492 aa 24.4 %
Onchocerca volvulus Carnitine O-palmitoyltransferase 2, mitochondrial homolog Cholinesterase   574 aa 554 aa 36.1 %
Brugia malayi Carboxylesterase family protein Cholinesterase   574 aa 538 aa 31.4 %
Loa Loa (eye worm) hypothetical protein Acetylcholinesterase   633 aa 576 aa 23.4 %
Drosophila melanogaster CG10175 gene product from transcript CG10175-RE Acetylcholinesterase   633 aa 549 aa 30.4 %
Echinococcus multilocularis neuroligin Acetylcholinesterase   633 aa 507 aa 23.9 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi nuclear receptor NHR-67 0.0015 0.0003 0.0005
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0062 0.0955
Schistosoma mansoni caspase-3 (C14 family) 0.0096 0.0148 0.0146
Trypanosoma cruzi hexose transporter 0.0032 0.0035 0.0505
Loa Loa (eye worm) hypothetical protein 0.0364 0.0622 0.2165
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0301 0.1046
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0075 0.0111 0.0109
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0035 0.0547
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0064 0.0091 0.031
Trypanosoma brucei glucose transporter, putative 0.0032 0.0035 0.0547
Plasmodium vivax calpain, putative 0.0019 0.0011 0.012
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0168 0.0275 0.0958
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Brugia malayi AMP-binding enzyme family protein 0.0077 0.0113 0.0387
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Schistosoma mansoni glucose transport protein 0.0104 0.0162 0.016
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0305 0.0518 0.6375
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0077 0.0113 0.2491
Brugia malayi F/Y-rich N-terminus family protein 0.0037 0.0042 0.0141
Brugia malayi Serotonin receptor 0.0124 0.0197 0.068
Echinococcus granulosus transient receptor potential cation channel 0.0075 0.0111 0.0111
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0197 0.0196
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Loa Loa (eye worm) hypothetical protein 0.0113 0.0178 0.062
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0077 0.0113 0.2168
Schistosoma mansoni hypothetical protein 0.0064 0.0091 0.0089
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0184 0.0304 0.2392
Echinococcus multilocularis isocitrate dehydrogenase 0.0048 0.0062 0.0059
Brugia malayi hypothetical protein 0.0106 0.0166 0.0571
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0019 0.0011 0.012
Echinococcus multilocularis calpain A 0.0066 0.0095 0.0092
Toxoplasma gondii exonuclease III APE 0.0056 0.0077 0.1457
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0003 0.0001
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0032 0.0031
Loa Loa (eye worm) voltage-gated calcium channel 0.0075 0.0111 0.0387
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0003 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0032 0.0105
Leishmania major cathepsin L-like protease 0.0016 0.0007 0.0029
Brugia malayi Patched related family protein 4 0.0017 0.0008 0.0022
Loa Loa (eye worm) Smad1 0.0041 0.0051 0.0177
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0055 0.0881
Onchocerca volvulus 0.0113 0.0178 0.1369
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0062 0.1167
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) hypothetical protein 0.0263 0.0444 0.1545
Echinococcus multilocularis short transient receptor potential channel 6 0.0201 0.0334 0.0331
Brugia malayi Melatonin receptor type 1A 0.0124 0.0197 0.068
Echinococcus granulosus Smad4 0.0041 0.0051 0.005
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0136 0.0136
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0075 0.0111 0.0381
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.016 0.0261 0.2306
Echinococcus granulosus potassium voltage gated channel protein 0.0075 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0029
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0007 0.0003
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0287 0.0486 0.5973
Echinococcus multilocularis beta LACTamase domain containing family member 0.0113 0.0178 0.0175
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0053 0.0071 0.0068
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0075 0.0111 0.0111
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0195 0.0323 0.1123
Loa Loa (eye worm) transcription factor SMAD2 0.0609 0.1057 0.3678
Schistosoma mansoni smad1 5 8 and 0.0041 0.0051 0.0049
Toxoplasma gondii transporter, cation channel family protein 0.0075 0.0111 0.2132
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.0518 0.402
Echinococcus granulosus caspase 2 0.0026 0.0023 0.0022
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0077 0.0113 0.0874
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0011 0.0168
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0124 0.0197 0.0194
Schistosoma mansoni smad1 5 8 and 0.0041 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Echinococcus multilocularis sentrin specific protease 7 0.0469 0.081 0.0807
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0075 0.0111 0.0108
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.0178 0.1382
Schistosoma mansoni alpha-1 adrenergic receptor 0.0124 0.0197 0.0195
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.0178 0.0176
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0097 0.015 0.0515
Echinococcus granulosus p2X purinoceptor 4 0.0134 0.0215 0.0214
Onchocerca volvulus 0.0015 0.0003 0.0011
Echinococcus granulosus potassium voltage gated channel protein 0.0075 0.0111 0.0111
Leishmania major protein kinase, putative 0.0038 0.0045 0.0376
Schistosoma mansoni amine GPCR 0.0124 0.0197 0.0195
Loa Loa (eye worm) hypothetical protein 0.0115 0.0181 0.0631
Echinococcus multilocularis lamin dm0 0.0083 0.0125 0.0122
Onchocerca volvulus 0.0016 0.0007 0.0036
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0077 0.0598
Brugia malayi Patched related family protein 10 0.0017 0.0008 0.0022
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0007 0.0036
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0011 0.0168
Schistosoma mansoni Mername-AA248 (C02 family) 0.0019 0.0011 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.0518 0.402
Loa Loa (eye worm) hypothetical protein 0.0164 0.0268 0.0932
Loa Loa (eye worm) hypothetical protein 0.0195 0.0323 0.1123
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0066 0.0094 0.0723
Echinococcus multilocularis allatostatin A receptor 0.0124 0.0197 0.0194
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0038 0.0045 0.0045
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0124 0.0197 0.0195
Brugia malayi Cathepsin L-like precursor 0.0016 0.0007 0.0016
Brugia malayi MH2 domain containing protein 0.0609 0.1057 0.3674
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0077 0.1192
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0147 0.0239 0.0237
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Brugia malayi cation channel family protein 0.0075 0.0111 0.0381
Onchocerca volvulus 0.0017 0.0008 0.005
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0113 0.3121
Brugia malayi G-protein coupled receptor 0.0124 0.0197 0.068
Mycobacterium tuberculosis Conserved protein 0.0113 0.0178 0.1391
Schistosoma mansoni calpain C (C02 family) 0.0019 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0022
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0075 0.0111 0.0108
Onchocerca volvulus 0.0015 0.0003 0.0011
Schistosoma mansoni opsin-like receptor 0.0124 0.0197 0.0195
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0075 0.0111 0.0381
Echinococcus granulosus dna polymerase kappa 0.0019 0.0011 0.001
Echinococcus multilocularis cysteine protease 0.0016 0.0007 0.0003
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0038 0.0045 0.0042
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0007 0.0031
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0124 0.0197 0.0196
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0047 0.0061 0.0772
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0197 0.0195
Schistosoma mansoni ferritin 0.0017 0.0007 0.0005
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0164 0.0268 0.0266
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Mycobacterium tuberculosis Conserved protein 0.0113 0.0178 0.1391
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0168 0.0275 0.0272
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0011 0.0038
Mycobacterium ulcerans acyl-CoA synthetase 0.0261 0.044 0.9899
Loa Loa (eye worm) patched family protein 0.0017 0.0008 0.0028
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0023
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0064 0.0091 0.031
Leishmania major hypothetical protein, conserved 0.0047 0.0062 0.0522
Leishmania major cathepsin L-like protease 0.0016 0.0007 0.0029
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0003 0.0026
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0077 0.0113 0.2491
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0047 0.0061 0.1049
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0416 0.0715 0.2483
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0197 0.0196
Echinococcus multilocularis sentrin specific protease 8 0.0064 0.0091 0.0088
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0038 0.0045 0.0829
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0088 0.1413
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.015 0.0243 0.024
Echinococcus multilocularis mitogen activated protein kinase 11 0.0253 0.0427 0.0424
Schistosoma mansoni neuropeptide F-like receptor 0.0124 0.0197 0.0195
Loa Loa (eye worm) hypothetical protein 0.0147 0.0239 0.083
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0097 0.015 0.1784
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0032 0.003
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0011 0.0032
Schistosoma mansoni smad1 5 8 and 0.0041 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0092
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0113
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0019 0.0144
Brugia malayi Carboxylesterase family protein 0.0164 0.0268 0.0926
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0197 0.0194
Brugia malayi ion channel NompC 0.0075 0.0111 0.0381
Brugia malayi Carboxylesterase family protein 0.0028 0.0026 0.0086
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Schistosoma mansoni hypothetical protein 0.0119 0.0188 0.0186
Mycobacterium ulcerans acyl-CoA synthetase 0.0077 0.0113 0.2491
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0003 0.0005
Brugia malayi putative neuropeptide receptor NPR1 0.0124 0.0197 0.068
Onchocerca volvulus 0.0028 0.0026 0.0191
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0011 0.0008
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0073 0.0107 0.0104
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0113 0.2078
Onchocerca volvulus 0.0075 0.0111 0.085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0197 0.0195
Brugia malayi Cathepsin L-like precursor 0.0016 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.0195 0.0323 0.1123
Toxoplasma gondii protein kinase, putative 0.03 0.051 1
Echinococcus granulosus neuropeptide Y receptor 0.0124 0.0197 0.0196
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0038 0.0045 0.0045
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0051
Leishmania major cathepsin L-like protease 0.0063 0.0088 0.0763
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0032 0.0029
Onchocerca volvulus 0.0167 0.0274 0.2115
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.0518 0.402
Schistosoma mansoni calcium-activated potassium channel 0.0075 0.0111 0.0109
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0035 0.0505
Loa Loa (eye worm) hypothetical protein 0.0416 0.0715 0.2488
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0054 0.0051
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0064 0.0091 0.0089
Echinococcus granulosus sex peptide receptor 0.0124 0.0197 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0179
Echinococcus granulosus General substrate transporter 0.0089 0.0136 0.0135
Brugia malayi hypothetical protein 0.0333 0.0569 0.1974
Echinococcus granulosus hyperpolarization activated cyclic 0.0075 0.0111 0.0111
Echinococcus multilocularis serotonin receptor 0.0244 0.041 0.0407
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0075 0.0111 0.0109
Echinococcus multilocularis p2X purinoceptor 4 0.0134 0.0215 0.0212
Loa Loa (eye worm) hypothetical protein 0.0263 0.0444 0.1545
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0011 0.0168
Brugia malayi MH2 domain containing protein 0.0019 0.001 0.0029
Loa Loa (eye worm) carboxylesterase 0.0164 0.0268 0.0932
Onchocerca volvulus 0.0028 0.0026 0.0191
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0023 0.0179
Loa Loa (eye worm) sugar transporter 0.0015 0.0003 0.0011
Echinococcus granulosus neuropeptide s receptor 0.1501 0.264 0.2639
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0077 0.0076
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.015 0.0243 0.0242
Echinococcus granulosus expressed protein 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0941 0.1647 0.1644
Echinococcus granulosus beta LACTamase domain containing family member 0.0113 0.0178 0.0178
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0015 0.0045
Schistosoma mansoni amine GPCR 0.0124 0.0197 0.0195
Onchocerca volvulus 0.0077 0.0113 0.0864
Echinococcus multilocularis neuropeptide receptor 0.0124 0.0197 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0007 0.0051
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0197 0.0195
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0032 0.0105
Loa Loa (eye worm) hypothetical protein 0.0125 0.0198 0.069
Toxoplasma gondii transporter, cation channel family protein 0.0093 0.0142 0.2744
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0011 0.0124
Loa Loa (eye worm) hypothetical protein 0.0151 0.0245 0.0852
Echinococcus multilocularis mitogen activated protein kinase 3 0.016 0.0261 0.0257
Echinococcus granulosus survival motor neuron protein 1 0.1168 0.2049 0.2049
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) voltage-gated potassium channel 0.0251 0.0423 0.1472
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0048 0.0062 0.0061
Brugia malayi metabotropic glutamate receptor type 2 0.0026 0.0024 0.0078
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Echinococcus granulosus mitogen activated protein kinase 14 0.0253 0.0427 0.0426
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0064 0.0091 0.0705
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0077 0.1366
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0011 0.0124
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0028 0.0026 0.0025
Brugia malayi cytoplasmic intermediate filament protein 0.0045 0.0056 0.019
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0077 0.0982
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0019 0.0011 0.0163
Brugia malayi cation channel family protein 0.0075 0.0111 0.0381
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0011 0.012
Echinococcus multilocularis serotonin receptor 0.0244 0.041 0.0407
Echinococcus multilocularis caspase 3 0.0071 0.0102 0.0099
Echinococcus granulosus neuropeptide receptor 0.0124 0.0197 0.0196
Echinococcus granulosus sodium leak channel non selective protein 0.0075 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0126 0.02 0.0696
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0067 0.0063
Echinococcus multilocularis cpg binding protein 0.0065 0.0093 0.009
Schistosoma mansoni opsin-like receptor 0.0124 0.0197 0.0195
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0032 0.0029
Toxoplasma gondii facilitative glucose transporter GT1 0.0104 0.0162 0.3129
Brugia malayi Latrophilin receptor protein 2 0.0193 0.0319 0.1105
Echinococcus granulosus sentrin specific protease 7 0.0469 0.081 0.0809
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0048 0.0062 0.0792
Schistosoma mansoni patched 1 0.0123 0.0196 0.0194
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Onchocerca volvulus 0.0263 0.0444 0.3433
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0197 0.0196
Leishmania major hypothetical protein, conserved 0.0113 0.0178 0.1567
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0042 0.0345
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0032 0.003
Brugia malayi Intermediate filament tail domain containing protein 0.0083 0.0125 0.0428
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0015 0.0102
Loa Loa (eye worm) patched family protein 0.0017 0.0008 0.0028
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0097 0.015 0.1162
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0035 0.028
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Toxoplasma gondii hypothetical protein 0.0026 0.0024 0.0414
Echinococcus multilocularis potassium voltage gated channel protein 0.0075 0.0111 0.0108
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0024 0.0394
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Entamoeba histolytica acyl-CoA synthetase, putative 0.0261 0.044 0.5392
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0003 0.0011
Echinococcus granulosus biogenic amine 5HT receptor 0.0495 0.0856 0.0855
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0042
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0011 0.0163
Trichomonas vaginalis set domain proteins, putative 0.074 0.129 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.0178 0.1382
Plasmodium vivax vivapain-2 0.0016 0.0007 0.0066
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0003 0.0011
Echinococcus granulosus two pore calcium channel protein 2 0.0075 0.0111 0.0111
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Echinococcus granulosus short transient receptor potential channel 6 0.0201 0.0334 0.0333
Echinococcus multilocularis g protein coupled receptor 0.0124 0.0197 0.0194
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0261 0.044 1
Echinococcus granulosus methyl CpG binding domain protein 2 0.0053 0.0071 0.0071
Brugia malayi jmjC domain containing protein 0.0102 0.0158 0.0543
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0193 0.0319 0.0316
Brugia malayi CXXC zinc finger family protein 0.0056 0.0077 0.0262
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0327 0.0557 0.1933
Echinococcus multilocularis hypothetical protein 0.0019 0.0011 0.0008
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0032 0.0032
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0092
Entamoeba histolytica acyl-coA synthetase, putative 0.0261 0.044 0.5392
Echinococcus granulosus calpain A 0.0066 0.0095 0.0094
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Schistosoma mansoni hypothetical protein 0.0838 0.1463 0.1461
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0011 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0179
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0197 0.0194
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0202 0.0336 0.1168
Schistosoma mansoni BC026374 protein (S09 family) 0.0028 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0533 0.0922 0.3208
Loa Loa (eye worm) hypothetical protein 0.0077 0.0113 0.0393
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0064 0.0091 0.1416
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0011 0.0066
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0301 0.0299
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0064 0.0091 0.1051
Plasmodium vivax metacaspase 1, putative 0.0026 0.0023 0.028
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0032 0.0105
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0124 0.0197 0.0195
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0035 0.0547
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0007 0.0005
Loa Loa (eye worm) RNA binding protein 0.0202 0.0336 0.1168
Brugia malayi sulfakinin receptor protein 0.0333 0.0569 0.1974
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0077 0.0113 0.1774
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0113 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0075 0.0111 0.0109
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0253 0.0427 0.3796
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0197 0.0194
Brugia malayi AMP-binding enzyme family protein 0.0261 0.044 0.1525
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0644 0.1119 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0023 0.039
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0007 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0124 0.0197 0.0196
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0131 0.0209 0.333
Toxoplasma gondii patched family protein 0.0017 0.0008 0.0098
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0077 0.0113 0.2491
Onchocerca volvulus 0.0017 0.0008 0.005
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4932 0.8723 0.8722
Echinococcus granulosus Protein patched homolog 1 0.0123 0.0196 0.0195
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0003 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Brugia malayi hypothetical protein 0.0124 0.0197 0.068
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0044 0.0041
Loa Loa (eye worm) hypothetical protein 0.0064 0.0091 0.0316
Brugia malayi ecdysone receptor 0.0015 0.0003 0.0005
Schistosoma mansoni jumonji/arid domain-containing protein 0.0047 0.006 0.0058
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0469 0.081 1
Onchocerca volvulus 0.0015 0.0003 0.0011
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0301 0.104
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0038 0.0045 0.0045
Schistosoma mansoni acetylcholinesterase 0.0028 0.0026 0.0025
Echinococcus granulosus transient receptor potential cation channel 0.0075 0.0111 0.0111
Trypanosoma brucei metacaspase 0.0026 0.0023 0.0362
Schistosoma mansoni Smad4 0.0019 0.001 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0088 0.1413
Echinococcus multilocularis neuropeptide Y receptor 0.0124 0.0197 0.0194
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0003 0.0005
Brugia malayi calpain 5 0.0019 0.0011 0.0031
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0003 0.0005
Schistosoma mansoni transient receptor potential channel 4 0.0269 0.0454 0.0452
Echinococcus multilocularis caspase 8 0.0026 0.0023 0.002
Giardia lamblia DINP protein human, muc B family 0.0019 0.0011 0.0149
Echinococcus multilocularis two pore calcium channel protein 2 0.0075 0.0111 0.0108
Toxoplasma gondii hypothetical protein 0.0075 0.0111 0.2132
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0077 0.0113 0.0874
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0011 0.0163
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0088 0.1413
Onchocerca volvulus 0.0124 0.0197 0.1515
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0147 0.0239 0.0235
Brugia malayi Bromodomain containing protein 0.0119 0.0188 0.0649
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0032 0.003
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0008 0.0005
Schistosoma mansoni hypothetical protein 0.0124 0.0197 0.0195
Echinococcus multilocularis g-protein coupled receptor 0.0124 0.0197 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0028 0.0026 0.0025
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Echinococcus multilocularis calpain 0.0019 0.0011 0.0008
Leishmania major cathepsin L-like protease 0.0063 0.0088 0.0763
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0124 0.0197 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0047 0.0061 0.5228
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0007 0.0051
Chlamydia trachomatis deubiquitinase/deneddylase Dub1 0.0064 0.0091 0.2379
Onchocerca volvulus 0.0016 0.0007 0.0036
Echinococcus multilocularis caspase 2 0.0026 0.0023 0.002
Schistosoma mansoni cpg binding protein 0.0056 0.0077 0.0075
Schistosoma mansoni P2X receptor subunit 0.0134 0.0215 0.0213
Echinococcus granulosus calcium activated potassium channel 0.0084 0.0126 0.0126
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0038 0.0045 0.057
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0364 0.0622 0.216
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0065 0.0991
Echinococcus granulosus transient receptor potential ion channel A 0.0193 0.032 0.0319
Schistosoma mansoni zinc finger protein 0.0064 0.0091 0.0089
Onchocerca volvulus 0.0028 0.0026 0.0191
Schistosoma mansoni adenoreceptor 0.0124 0.0197 0.0195
Echinococcus granulosus intermediate filament protein 0.0083 0.0125 0.0124
Schistosoma mansoni DNA helicase recq5 0.0021 0.0015 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0088 0.1413
Schistosoma mansoni gliotactin 0.0028 0.0026 0.0025
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Schistosoma mansoni glucose transport protein 0.0104 0.0162 0.016
Loa Loa (eye worm) hypothetical protein 0.0772 0.1347 0.4689
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0042 0.0525
Loa Loa (eye worm) calpain 0.0019 0.0011 0.0037
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Echinococcus granulosus neuropeptide receptor 0.0124 0.0197 0.0196
Onchocerca volvulus 0.0124 0.0197 0.1515
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0068 0.0097 0.0339
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.0178 0.1382
Schistosoma mansoni metabotropic glutamate receptor 0.0045 0.0058 0.0056
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Echinococcus multilocularis conserved hypothetical protein 0.0075 0.0111 0.0108
Brugia malayi AMP-binding enzyme family protein 0.0077 0.0113 0.0387
Echinococcus multilocularis g protein coupled receptor 0.0124 0.0197 0.0194
Brugia malayi Carboxylesterase family protein 0.0164 0.0268 0.0926
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0075 0.0111 0.0108
Echinococcus multilocularis muscleblind protein 0.0308 0.0523 0.052
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0033 0.057
Echinococcus multilocularis fmrfamide receptor 0.0124 0.0197 0.0194
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0077 0.0268
Onchocerca volvulus Alhambra homolog 0.0031 0.0032 0.0238
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0097 0.015 0.2893
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Brugia malayi Cam kinase protein 1 0.0038 0.0045 0.0151
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0011 0.0085
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0111
Brugia malayi Pre-SET motif family protein 0.065 0.1131 0.3932
Schistosoma mansoni hypothetical protein 0.0193 0.0319 0.0317
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0064 0.0091 0.1416
Schistosoma mansoni apoferritin-2 0.0017 0.0007 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.006 0.0209
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0092
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0075 0.0111 0.0381
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0011 0.012
Onchocerca volvulus 0.0056 0.0077 0.0583
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0019 0.0015
Echinococcus granulosus hypothetical protein 0.0124 0.0197 0.0196
Entamoeba histolytica acyl-CoA synthetase, putative 0.0261 0.044 0.5392
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0092
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0048 0.0062 0.0062
Brugia malayi hypothetical protein 0.0124 0.0197 0.068
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Echinococcus granulosus dro:myosuppressin receptor 0.0124 0.0197 0.0196
Schistosoma mansoni hypothetical protein 0.0119 0.0188 0.0186
Echinococcus granulosus solute carrier family 22 0.0015 0.0003 0.0003
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0253 0.0427 0.6845
Echinococcus multilocularis sodium channel protein 0.0682 0.1186 0.1183
Echinococcus multilocularis lamin 0.0083 0.0125 0.0122
Schistosoma mansoni bromodomain containing protein 0.02 0.0331 0.033
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0038 0.0045 0.0045
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0168 0.0275 0.0275
Echinococcus multilocularis somatostatin receptor 0.0124 0.0197 0.0194
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0197 0.0195
Loa Loa (eye worm) calpain family protein 1 0.0063 0.0089 0.0311
Loa Loa (eye worm) hypothetical protein 0.0097 0.015 0.0521
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0184 0.0304 0.2392
Mycobacterium ulcerans acyl-CoA synthetase 0.0077 0.0113 0.2491
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0197 0.0195
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0014 0.0014
Brugia malayi hypothetical protein 0.0015 0.0003 0.0005
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0168 0.0275 0.0273
Echinococcus granulosus short transient receptor potential channel 6 0.0201 0.0334 0.0333
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0301 0.0297
Trypanosoma cruzi metacaspase, putative 0.0026 0.0023 0.0319
Trypanosoma brucei glucose transporter, putative 0.0032 0.0035 0.0547
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0088 0.1413
Loa Loa (eye worm) hypothetical protein 0.0195 0.0323 0.1123
Chlamydia trachomatis deubiquitinase/deneddylase Dub2 0.0064 0.0091 0.2379
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0197 0.0195
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Brugia malayi latrophilin 2 splice variant baaae 0.0416 0.0716 0.2487
Echinococcus multilocularis dro:myosuppressin receptor 0.0124 0.0197 0.0194
Trypanosoma brucei unspecified product 0.0019 0.0011 0.0168
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0035
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0168 0.0275 0.0272
Loa Loa (eye worm) sugar transporter 0.0104 0.0162 0.0563
Schistosoma mansoni aldehyde dehydrogenase 0.0183 0.0302 0.03
Plasmodium vivax patched family protein, putative 0.0017 0.0008 0.0088
Loa Loa (eye worm) doublecortin family protein 0.002 0.0012 0.0042
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.0162 0.0159
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0193 0.0319 0.1105
Loa Loa (eye worm) hypothetical protein 0.0263 0.0444 0.1545
Schistosoma mansoni hypothetical protein 0.015 0.0243 0.0241
Brugia malayi G protein-coupled receptor 0.0124 0.0197 0.068
Loa Loa (eye worm) G-protein coupled receptor 0.0124 0.0197 0.0685
Echinococcus granulosus zinc finger protein 0.0064 0.0091 0.009
Onchocerca volvulus 0.0015 0.0003 0.0011
Trypanosoma brucei sugar transporter, putative 0.0015 0.0003 0.0044
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Leishmania major phosphopantetheinyl transferase-like protein 0.0047 0.0061 0.0516
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0238 0.04 0.1387
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0075 0.0111 0.0111
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0019 0.0222
Brugia malayi nuclear hormone receptor 0.0015 0.0003 0.0005
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.016 0.0261 0.4158
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Brugia malayi map kinase activated protein kinase protein 2 0.1633 0.2873 1
Brugia malayi RE15519p 0.0124 0.0197 0.068
Onchocerca volvulus 0.0124 0.0197 0.1515
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0364 0.0622 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0124 0.0197 0.1515
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0469 0.081 0.0808
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0019 0.0261
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0032 0.003
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0333 0.0569 0.1979
Mycobacterium ulcerans acetyl-CoA synthetase 0.0077 0.0113 0.2491
Mycobacterium ulcerans acyl-CoA synthetase 0.0077 0.0113 0.2491
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0327 0.0557 0.0556
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0023 0.028
Plasmodium falciparum protein kinase 7 0.03 0.051 0.6602
Echinococcus multilocularis protein dispatched 1 0.0141 0.0227 0.0223
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0113 0.2499
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0075 0.0111 0.0387
Giardia lamblia Kinase, CMGC MAPK 0.016 0.0261 0.4995
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0007 0.0029
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0195 0.0323 1
Schistosoma mansoni caspase-7 (C14 family) 0.0026 0.0023 0.0021
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0009 0.0086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0032 0.0111
Echinococcus granulosus sentrin specific protease 1 0.0097 0.015 0.0149
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0301 0.03
Schistosoma mansoni amine GPCR 0.0124 0.0197 0.0195
Onchocerca volvulus 0.0031 0.0032 0.0235
Echinococcus granulosus bloom syndrome protein 0.0021 0.0015 0.0014
Trypanosoma cruzi ISWI complex protein 0.0047 0.0062 0.0942
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0077 0.0113 0.1327
Schistosoma mansoni P2X receptor subunit 0.0134 0.0215 0.0213
Brugia malayi G protein-coupled receptor F59B2.13 0.0124 0.0197 0.068
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) voltage-gated potassium channel 0.0075 0.0111 0.0387
Echinococcus multilocularis musashi 0.0083 0.0125 0.0122
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0609 0.1058 0.3677
Loa Loa (eye worm) hypothetical protein 0.0244 0.041 0.1427
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0124 0.0197 0.0194
Trypanosoma brucei SUMO1/Ulp2, putative 0.0064 0.0091 0.1454
Echinococcus multilocularis expressed conserved protein 0.027 0.0455 0.0452
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0017 0.0007 0.0359
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0049 0.0045
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0003 0.0005
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0012 0.0012
Trypanosoma cruzi hypothetical protein 0.0064 0.0091 0.1416
Onchocerca volvulus 0.0261 0.044 0.3399
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0075 0.0111 0.0381
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0094 0.0145 0.0142
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Echinococcus multilocularis mitogen activated protein kinase 11 0.0253 0.0427 0.0424
Leishmania major cathepsin L-like protease 0.0016 0.0007 0.0029
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0023 0.039
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0011 0.001
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0033 0.0107
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0024 0.0333
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0113 0.0178 0.1391
Echinococcus multilocularis transient receptor potential ion channel A 0.0193 0.032 0.0317
Onchocerca volvulus Huntingtin homolog 0.0125 0.0198 0.1526
Echinococcus multilocularis caspase 0.0096 0.0148 0.0145
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0113 0.1455
Leishmania major metacaspase, putative 0.0026 0.0023 0.0177
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0077 0.1674
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0075 0.0111 0.0111
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0077 0.0982
Brugia malayi ecdysteroid receptor 0.0031 0.0032 0.0105
Loa Loa (eye worm) hypothetical protein 0.0039 0.0046 0.0159
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0261 0.044 0.9899
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0124 0.0197 0.068
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0003 0.0044
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0075 0.0111 0.0109
Schistosoma mansoni ap endonuclease 0.0056 0.0077 0.0075
Loa Loa (eye worm) voltage-dependent calcium channel 0.0093 0.0142 0.0495
Plasmodium falciparum hexose transporter 0.0104 0.0162 0.2082
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0723 0.126 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.0518 0.402
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0033 0.0031
Onchocerca volvulus 0.0015 0.0003 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0007 0.0051
Echinococcus multilocularis para nitrobenzyl esterase 0.0028 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Loa Loa (eye worm) voltage-gated potassium channel 0.0075 0.0111 0.0387
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0301 0.03
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0007
Echinococcus multilocularis mothers against decapentaplegic 5 0.0041 0.0051 0.0048
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0007 0.0051
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0042 0.0525
Onchocerca volvulus 0.0016 0.0007 0.0036
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0038 0.0045 0.057
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0045 0.0043
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0032 0.0569
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0015 0.0228
Giardia lamblia PHD finger protein 15 0.0031 0.0032 0.0566
Echinococcus granulosus GPCR family 2 0.0193 0.0319 0.0319
Brugia malayi neuropeptide F receptor 0.0124 0.0197 0.068
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.016 0.0261 0.2306
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0077 0.0878
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0149 0.0242 0.5423
Plasmodium vivax hexose transporter 0.0104 0.0162 0.2082
Trypanosoma cruzi metacaspase, putative 0.0026 0.0023 0.0319
Brugia malayi hypothetical protein 0.0124 0.0197 0.068
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0012 0.0139
Loa Loa (eye worm) hypothetical protein 0.0093 0.0142 0.0495
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.0685 0.0682
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Onchocerca volvulus 0.0263 0.0444 0.3433
Leishmania major glucose transporter, lmgt3 0.0032 0.0035 0.028
Schistosoma mansoni caspase-7 (C14 family) 0.0096 0.0148 0.0146
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0124 0.0197 0.0195
Echinococcus granulosus dna polymerase eta 0.0044 0.0055 0.0055
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0075 0.0111 0.0109
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Echinococcus granulosus neuropeptides capa receptor 0.0124 0.0197 0.0196
Entamoeba histolytica protein kinase, putative 0.0027 0.0026 0.0238
Brugia malayi AMP-binding enzyme family protein 0.0077 0.0113 0.0387
Brugia malayi isocitrate dehydrogenase 0.0048 0.0062 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0003 0.0026
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0047 0.0061 0.1393
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0007 0.0051
Plasmodium vivax acetyl-CoA synthetase, putative 0.0077 0.0113 0.145
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0075 0.0111 0.0108
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0006 0.0022
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0028 0.0026 0.0184
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0012 0.0012
Brugia malayi larval opioid receptor 0.0124 0.0197 0.068
Brugia malayi nuclear receptor RXR 0.0015 0.0003 0.0005
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0047 0.0061 0.1307
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0075 0.0111 0.0108
Loa Loa (eye worm) RecQ helicase 0.0021 0.0015 0.0051
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0048 0.0062 0.0995
Echinococcus multilocularis BC026374 protein (S09 family) 0.0028 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0119 0.0189 0.0656
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0041 0.0051 0.0049
Plasmodium falciparum calcium-dependent protein kinase 2 0.0038 0.0045 0.057
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.0518 0.402
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Schistosoma mansoni two-pore calcium channel 0.0075 0.0111 0.0109
Echinococcus multilocularis neuropeptide receptor A26 0.1501 0.264 0.2637
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0123 0.0195 0.0193
Leishmania major 4-coumarate:coa ligase-like protein 0.0261 0.044 0.391
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0003 0.0003
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0045 0.0056 0.0196
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0003 0.0005
Schistosoma mansoni lamin 0.0083 0.0125 0.0123
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0019 0.0222
Echinococcus multilocularis neuropeptides capa receptor 0.0124 0.0197 0.0194
Schistosoma mansoni sugar transporter 0.0015 0.0003 0.0001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0056 0.0077 0.0268
Brugia malayi MH1 domain containing protein 0.0023 0.0018 0.0057
Echinococcus granulosus potassium voltage gated channel protein 0.0075 0.0111 0.0111
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.0178 0.2826
Loa Loa (eye worm) DR-78 0.0015 0.0003 0.0011
Brugia malayi beta-lactamase family protein 0.0113 0.0178 0.0614
Brugia malayi hypothetical protein 0.0125 0.0198 0.0684
Schistosoma mansoni transient receptor potential channel 0.0201 0.0334 0.0332
Trichomonas vaginalis antibiotic synthetase, putative 0.0077 0.0113 0.0877
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0092
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1633 0.2873 0.287
Echinococcus granulosus acetylcholinesterase 0.0164 0.0268 0.0267
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0008 0.0005
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0124 0.0197 0.0195
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0032 0.0235
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0019 0.0246
Brugia malayi G-protein coupled receptor 0.0124 0.0197 0.068
Onchocerca volvulus 0.0017 0.0008 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0011 0.0168
Onchocerca volvulus Putative transporter 0.0015 0.0003 0.0011
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0143 0.0231 0.0228
Schistosoma mansoni ferritin 0.0017 0.0007 0.0005
Echinococcus multilocularis peregrin 0.0038 0.0046 0.0042
Brugia malayi tailless protein 0.0015 0.0003 0.0005
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0077 0.0113 0.0874
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0032 0.0576
Mycobacterium tuberculosis Probable lipase LipD 0.0113 0.0178 0.1391
Schistosoma mansoni hypothetical protein 0.0031 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0111
Schistosoma mansoni intermediate filament proteins 0.0083 0.0125 0.0123
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0011 0.012
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Echinococcus granulosus fmrfamide receptor 0.0124 0.0197 0.0196
Brugia malayi Carboxylesterase family protein 0.0028 0.0026 0.0086
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0077
Echinococcus granulosus orexin receptor type 2 0.0124 0.0197 0.0196
Trypanosoma brucei ISWI complex protein 0.0047 0.0062 0.0982
Echinococcus granulosus calpain 5 0.0019 0.0011 0.001
Echinococcus multilocularis dna polymerase eta 0.0044 0.0055 0.0052
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0077 0.0113 0.1811
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0007 0.0066
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0022
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0011 0.0168
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0032 0.003
Echinococcus granulosus g protein coupled receptor 0.0124 0.0197 0.0196
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0038 0.0045 0.0151
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0022
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0064 0.0091 0.173
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0032 0.0111
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Schistosoma mansoni tar DNA-binding protein 0.0202 0.0336 0.0334
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Echinococcus granulosus voltage dependent calcium channel 0.0168 0.0275 0.0275
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0168 0.0275 0.0273
Mycobacterium ulcerans lipase LipD 0.0113 0.0178 0.3967
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0124 0.0197 0.0195
Brugia malayi Sugar transporter family protein 0.0015 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Echinococcus granulosus tumor protein p63 0.0714 0.1244 0.1243
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0015 0.0003 0.0024
Trypanosoma brucei glucose transporter 1E 0.0032 0.0035 0.0547
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0038 0.0045 0.0829
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0067 0.1372
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Mycobacterium tuberculosis Carboxylesterase LipT 0.0028 0.0026 0.0184
Plasmodium vivax sentrin-specific protease 1, putative 0.0097 0.015 0.1927
Echinococcus granulosus somatostatin receptor 0.0124 0.0197 0.0196
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0113 0.2457
Brugia malayi MH2 domain containing protein 0.0041 0.0051 0.0171
Echinococcus granulosus sodium channel protein 0.0644 0.1119 0.1118
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0048 0.0062 0.0059
Trypanosoma cruzi metacaspase, putative 0.0026 0.0023 0.0319
Echinococcus multilocularis g protein coupled receptor 0.0124 0.0197 0.0194
Schistosoma mansoni glucose transport protein 0.0104 0.0162 0.016
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0011 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0003 0.0026
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0003 0.0001
Brugia malayi protein C24B5.3 0.0017 0.0008 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0011 0.0168
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0054 0.0053
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0302 0.6781
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0023 0.0179
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0012 0.0139
Trypanosoma brucei C-8 sterol isomerase, putative 0.0364 0.0622 1
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.001 0.001
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.0015 0.0014
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0028 0.0026 0.0025
Echinococcus granulosus ferritin 0.0017 0.0007 0.0007
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0077 0.0113 0.0387
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0113 0.2176
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0019 0.0136
Mycobacterium tuberculosis Conserved protein 0.0113 0.0178 0.1391
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0049 0.0048
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.003 0.0031 0.0108
Trypanosoma brucei glucose transporter, putative 0.0032 0.0035 0.0547
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Echinococcus multilocularis survival motor neuron protein 1 0.1168 0.2049 0.2046
Plasmodium falciparum metacaspase 1 0.0026 0.0023 0.028
Brugia malayi major facilitator superfamily protein 0.0015 0.0003 0.0005
Echinococcus multilocularis transient receptor potential cation channel 0.0075 0.0111 0.0108
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0075 0.0111 0.0111
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0077 0.0113 0.145
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.016 0.0261 0.4158
Onchocerca volvulus 0.002 0.0012 0.008
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0124 0.0197 0.0195
Loa Loa (eye worm) hypothetical protein 0.0195 0.0323 0.1123
Brugia malayi MAP kinase sur-1 0.016 0.0261 0.0901
Schistosoma mansoni microtubule-associated protein tau 0.5652 1 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.0162 0.0161
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Brugia malayi Carboxylesterase family protein 0.0028 0.0026 0.0086
Toxoplasma gondii aldehyde dehydrogenase 0.0183 0.0302 0.5903
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0019 0.0018
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0038 0.0045 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0011 0.0168
Schistosoma mansoni myosin xvIII 0.0124 0.0197 0.0195
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0167 0.0274 0.0272
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0042 0.0761
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0077 0.1192
Schistosoma mansoni bromodomain containing protein 0.0016 0.0007 0.0005
Leishmania major acetyl-CoA synthetase, putative 0.0077 0.0113 0.0984
Mycobacterium ulcerans beta-lactamase 0.0113 0.0178 0.3967
Plasmodium falciparum calcium-dependent protein kinase 5 0.0038 0.0045 0.057
Echinococcus multilocularis neuropeptide Y receptor 0.0124 0.0197 0.0194
Onchocerca volvulus 0.0124 0.0197 0.1515
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0003 0.0003
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0075 0.0111 0.0111
Echinococcus granulosus expressed conserved protein 0.027 0.0455 0.0455
Echinococcus granulosus ryanodine receptor 44f 0.0076 0.0111 0.0111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0088 0.1413
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0048 0.0062 0.0792
Brugia malayi steroid hormone receptor 0.0031 0.0032 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0003 0.0026
Onchocerca volvulus 0.0028 0.0026 0.0191
Brugia malayi Bromodomain containing protein 0.0236 0.0396 0.1372
Echinococcus multilocularis geminin 0.0838 0.1463 0.146
Plasmodium falciparum metacaspase-like protein 0.0026 0.0023 0.028
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0168 0.0275 0.0275
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0048 0.0062 0.0955
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0019 0.0289
Schistosoma mansoni hypothetical protein 0.0047 0.0062 0.006
Schistosoma mansoni ryanodine receptor related 0.0076 0.0111 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0197 0.0195
Trypanosoma brucei antigen, putative 0.0019 0.0011 0.0163
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0075 0.0111 0.0381
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0003 0.0001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0032 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0261 0.0259
Toxoplasma gondii patched family protein 0.0017 0.0008 0.0098
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0006 0.0003
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0003 0.0011
Schistosoma mansoni biogenic amine receptor 0.0124 0.0197 0.0195
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0033 0.0035 0.0033
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0772 0.1347 0.4686
Brugia malayi hypothetical protein 0.0017 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0269 0.0454 0.158
Echinococcus granulosus metabotropic glutamate receptor 2 0.0045 0.0058 0.0057
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0028 0.0026 0.0205
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0003 0.0026
Echinococcus granulosus tm gpcr rhodopsin 0.0124 0.0197 0.0196
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0079 0.1219
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0075 0.0111 0.0109
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0075 0.0111 0.0109
Onchocerca volvulus 0.0015 0.0003 0.001
Schistosoma mansoni apoferritin-2 0.0017 0.0007 0.0005
Plasmodium falciparum protein kinase 6 0.0448 0.0771 1
Echinococcus granulosus carboxylesterase 5A 0.0164 0.0268 0.0267
Echinococcus granulosus shaker cognate 0.0075 0.0111 0.0111
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0077 0.0113 0.2491
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0088 0.1413
Onchocerca volvulus 0.0263 0.0444 0.3433
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0037 0.0042 0.0039
Echinococcus multilocularis neuropeptide receptor 0.0124 0.0197 0.0194
Echinococcus granulosus BC026374 protein S09 family 0.0028 0.0026 0.0026
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0075 0.0111 0.0108
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0075 0.0111 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.1633 0.2873 0.2871
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0032 0.0031
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0007 0.0036
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0302 0.6781
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0011 0.0168
Mycobacterium ulcerans acyl-CoA synthetase 0.0261 0.044 0.9899
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0028 0.0026 0.0023
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0066 0.0095 0.0094
Loa Loa (eye worm) hypothetical protein 0.0261 0.044 0.153
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Schistosoma mansoni amine GPCR 0.0124 0.0197 0.0195
Echinococcus multilocularis short transient receptor potential channel 6 0.0201 0.0334 0.0331
Schistosoma mansoni jumonji/arid domain-containing protein 0.0047 0.006 0.0058
Brugia malayi MH1 domain containing protein 0.0023 0.0018 0.0057
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.003 0.0027
Trichomonas vaginalis ferritin, putative 0.0017 0.0007 0.0057
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0008 0.0008
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0023 0.0319
Brugia malayi nuclear hormone receptor 0.0031 0.0032 0.0105
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0011 0.0069
Plasmodium falciparum mitogen-activated protein kinase 2 0.0174 0.0287 0.3706
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0124 0.0197 0.0685
Onchocerca volvulus 0.0017 0.0008 0.005
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0049 0.0064 0.0218
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0022 0.0016 0.0211
Toxoplasma gondii hypothetical protein 0.0075 0.0111 0.2132
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0179
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0007 0.0051
Leishmania major cathepsin L-like protease 0.0063 0.0088 0.0763
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0015 0.0172
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Brugia malayi Patched protein homolog 1 0.0017 0.0008 0.0022
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0033 0.0254
Echinococcus granulosus two pore calcium channel protein 1 0.0075 0.0111 0.0111
Schistosoma mansoni lamin 0.0083 0.0125 0.0123
Leishmania major cathepsin L-like protease 0.0016 0.0007 0.0029
Echinococcus granulosus mothers against decapentaplegic 5 0.0041 0.0051 0.005
Echinococcus granulosus voltage dependent calcium channel 0.0093 0.0142 0.0142
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0062 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0032 0.0105
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0188 0.0312 0.0309
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.001 0.0007
Brugia malayi hypothetical protein 0.0124 0.0197 0.068
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0113 0.011
Schistosoma mansoni biogenic amine receptor 0.0124 0.0197 0.0195
Echinococcus multilocularis expressed conserved protein 0.0405 0.0696 0.0693
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0032 0.0105
Loa Loa (eye worm) hypothetical protein 0.0167 0.0274 0.0954
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0003 0.0005
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0047 0.0061 0.0772
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0188 0.0312 0.0311
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0035 0.0268
Echinococcus multilocularis acetylcholinesterase 0.0164 0.0268 0.0265
Loa Loa (eye worm) hypothetical protein 0.0143 0.0231 0.0805
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0035 0.0268
Echinococcus granulosus tachykinin peptides receptor 99D 0.0124 0.0197 0.0196
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0113 0.0178 0.1391
Echinococcus multilocularis transient receptor potential cation channel 0.0075 0.0111 0.0108
Leishmania major glucose transporter, lmgt2 0.0032 0.0035 0.028
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0077 0.0587
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0019 0.001 0.0065
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0301 0.0299
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0003 0.001
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0077 0.0113 0.0874
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0032 0.0105
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0032 0.0029
Echinococcus multilocularis Smad4 0.0041 0.0051 0.0048
Onchocerca volvulus 0.0124 0.0197 0.1515
Onchocerca volvulus 0.0016 0.0007 0.0036
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0075 0.0111 0.0381
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0003 0.0011
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0012 0.0009
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0064 0.0091 0.0705
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0028 0.0026 0.0026
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0011 0.012
Leishmania major DNA polymerase eta, putative 0.0044 0.0055 0.0466
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0032 0.0111
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0032 0.0031
Echinococcus multilocularis transfer RNA-Gly 0.0075 0.0111 0.0108
Schistosoma mansoni tar DNA-binding protein 0.0202 0.0336 0.0334
Schistosoma mansoni hypothetical protein 0.0193 0.0319 0.0317
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0063 0.0089 0.0088
Entamoeba histolytica hypothetical protein 0.015 0.0243 0.2943
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0111
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0014 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0044 0.0055 0.0192
Toxoplasma gondii hypothetical protein 0.0017 0.0008 0.0098
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0197 0.0194
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0062 0.0995
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0197 0.0194
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Onchocerca volvulus Huntingtin homolog 0.0125 0.0198 0.1526
Loa Loa (eye worm) glutamate receptor 0.0021 0.0015 0.0053
Schistosoma mansoni rab6-interacting 0.002 0.0012 0.001
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0124 0.0197 0.068
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0032 0.003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0011 0.012
Trypanosoma cruzi metacaspase, putative 0.0026 0.0023 0.0319
Echinococcus granulosus serotonin receptor 0.0124 0.0197 0.0196
Echinococcus granulosus tar DNA binding protein 0.0202 0.0336 0.0335
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.0162 0.0161
Schistosoma mansoni biogenic amine (5HT) receptor 0.0244 0.041 0.0408
Trypanosoma brucei metacaspase MCA2 0.0026 0.0023 0.0362
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0113 0.0178 0.1391
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0091 0.0317
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0007 0.0022
Loa Loa (eye worm) hypothetical protein 0.0125 0.0198 0.069
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0075 0.0111 0.0381
Schistosoma mansoni loxhd1 0.002 0.0012 0.001
Brugia malayi Dopamine receptor protein 2 0.0124 0.0197 0.068
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0011 0.0168
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0197 0.0194
Onchocerca volvulus 0.0015 0.0003 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0088 0.1413
Echinococcus granulosus para nitrobenzyl esterase 0.0028 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.016 0.0261 0.4184
Schistosoma mansoni tar DNA-binding protein 0.0202 0.0336 0.0334
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Schistosoma mansoni protein kinase 0.0038 0.0045 0.0043
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0124 0.0197 0.0194
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0032 0.0029
Echinococcus multilocularis transient receptor potential cation channel 0.0075 0.0111 0.0108
Onchocerca volvulus 0.0017 0.0008 0.005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0032 0.0031
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0011 0.0163
Giardia lamblia Sentrin specific protease, putative 0.0064 0.0091 0.17
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0077 0.0113 0.1774
Schistosoma mansoni ferritin light chain 0.0017 0.0007 0.0005
Entamoeba histolytica protein kinase, putative 0.0038 0.0045 0.0482
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0077 0.1432
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0012 0.0072
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0032 0.0029
Brugia malayi Pre-SET motif family protein 0.0094 0.0145 0.0498
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0088 0.1413
Trypanosoma brucei glucose transporter, putative 0.0032 0.0035 0.0547
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Loa Loa (eye worm) fibroinase 0.0016 0.0007 0.0022
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Echinococcus multilocularis potassium large conductance calcium activated 0.0075 0.0111 0.0108
Loa Loa (eye worm) calpain family protein 1 0.0044 0.0056 0.0195
Echinococcus granulosus caspase 0.0096 0.0148 0.0147
Loa Loa (eye worm) hypothetical protein 0.0064 0.0091 0.0316
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0011 0.0174
Loa Loa (eye worm) oxidoreductase 0.0077 0.0113 0.0393
Schistosoma mansoni biogenic amine (5HT) receptor 0.0495 0.0856 0.0854
Brugia malayi calpain family protein 1 0.0063 0.0089 0.0305
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0064 0.0091 0.0705
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0077 0.0113 0.0874
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0124 0.0197 0.0194
Schistosoma mansoni sugar transporter 0.0015 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Onchocerca volvulus 0.0028 0.0026 0.0191
Onchocerca volvulus 0.0124 0.0197 0.1515
Brugia malayi Cathepsin L-like precursor 0.0016 0.0007 0.0016
Echinococcus granulosus TGF beta signal transducer SmadC 0.0041 0.0051 0.005
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0075 0.0111 0.0109
Brugia malayi ORL1-like opioid receptor 0.0124 0.0197 0.068
Echinococcus granulosus potassium voltage gated channel subfamily KQT 0.0115 0.0181 0.0181
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0077 0.0113 0.2448
Trypanosoma cruzi ISWI complex protein 0.0047 0.0062 0.0942
Brugia malayi Doublecortin family protein 0.002 0.0012 0.0036
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0026 0.0024
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0075 0.0111 0.2132
Loa Loa (eye worm) neuropeptide F receptor 0.0124 0.0197 0.0685
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Trypanosoma brucei Metacaspase-4 0.0026 0.0023 0.0362
Mycobacterium leprae Probable lipase LipE 0.0113 0.0178 0.3953
Plasmodium vivax hypothetical protein, conserved 0.0113 0.0178 0.2296
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0064 0.0091 0.173
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0015 0.0045
Brugia malayi TAR-binding protein 0.0202 0.0336 0.1163
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0096 0.0148 0.0147
Onchocerca volvulus 0.0124 0.0197 0.1515
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.0095 0.0093
Entamoeba histolytica hypothetical protein 0.015 0.0243 0.2943
Schistosoma mansoni ferritin 0.0017 0.0007 0.0005
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0077 0.0113 0.0112
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0032 0.003
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0096 0.0148 0.0145
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0609 0.1058 0.3681
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0038 0.0045 0.0042
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0011 0.0163
Entamoeba histolytica ARF GTPase activating protein, putative 0.0029 0.0029 0.0276
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0023 0.0179
Echinococcus multilocularis tumor protein p63 0.0714 0.1244 0.1241
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0032 0.003
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0032 0.0111
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0007 0.0003
Brugia malayi Niemann-Pick C1 protein precursor 0.0287 0.0486 0.1687
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0168
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0183 0.0302 0.2378
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0168 0.0275 0.0275
Schistosoma mansoni opsin-like receptor 0.0124 0.0197 0.0195
Treponema pallidum fructose-bisphosphate aldolase 0.0305 0.0518 1
Plasmodium vivax sentrin-specific protease 2, putative 0.0064 0.0091 0.1162
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0003 0.0026
Mycobacterium ulcerans acyl-CoA synthetase 0.0261 0.044 0.9899
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0088 0.1375
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0077 0.0113 0.0874
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0012 0.0117
Echinococcus granulosus calcium dependent protein kinase 0.003 0.003 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0011 0.0168
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0075 0.0111 0.0387
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0011 0.0163
Brugia malayi major facilitator superfamily protein 0.0015 0.0003 0.0005
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0097 0.015 0.0148
Schistosoma mansoni neuropeptide receptor 0.0124 0.0197 0.0195
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0007 0.0051
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0024 0.0296
Brugia malayi hypothetical protein 0.0015 0.0003 0.0005
Trypanosoma cruzi kinesin, putative 0.0019 0.0011 0.012
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0015 0.0225
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0113 0.0178 0.3967
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1633 0.2873 0.2872
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0032 0.0105
Leishmania major 4-coumarate:coa ligase-like protein 0.0261 0.044 0.391
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0038 0.0045 0.072
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0032 0.0113
Trichomonas vaginalis Sentrin-specific protease, putative 0.0064 0.0091 0.0705
Mycobacterium ulcerans hypothetical protein 0.0261 0.044 0.9899
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0032 0.0111
Schistosoma mansoni tar DNA-binding protein 0.0202 0.0336 0.0334
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0066 0.0095 0.0092
Echinococcus granulosus lamin 0.0083 0.0125 0.0124
Loa Loa (eye worm) hypothetical protein 0.0113 0.0178 0.062
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0111
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0088 0.1375
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0124 0.0197 0.0194
Brugia malayi Carboxylesterase family protein 0.0028 0.0026 0.0086
Echinococcus multilocularis p2X purinoceptor 4 0.0134 0.0215 0.0212
Loa Loa (eye worm) hypothetical protein 0.0308 0.0523 0.182
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0075 0.0111 0.085
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0113 0.2499
Plasmodium falciparum calcium-dependent protein kinase 4 0.0038 0.0045 0.057
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0261 0.2021
Schistosoma mansoni voltage-gated ion channel 0.0075 0.0111 0.0109
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0032 0.0029
Brugia malayi hypothetical protein 0.002 0.0012 0.0036
Echinococcus granulosus peregrin 0.0038 0.0046 0.0045
Loa Loa (eye worm) hypothetical protein 0.0067 0.0096 0.0333
Onchocerca volvulus 0.0113 0.0178 0.1369
Schistosoma mansoni lipoxygenase 0.0117 0.0185 0.0184
Brugia malayi Cyclic-nucleotide gated cation channel 0.0075 0.0111 0.0381
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0047 0.0061 0.1137
Schistosoma mansoni histamine h1 receptor 0.0124 0.0197 0.0195
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0015 0.0045
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0035 0.0505
Trypanosoma brucei hypothetical protein, conserved 0.0113 0.0178 0.2858
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Echinococcus multilocularis carboxylesterase 5A 0.0164 0.0268 0.0265
Loa Loa (eye worm) hypothetical protein 0.0416 0.0715 0.2488
Brugia malayi hypothetical protein 0.0124 0.0197 0.068
Onchocerca volvulus 0.0015 0.0003 0.0011
Brugia malayi Sugar transporter family protein 0.0104 0.0162 0.0557
Onchocerca volvulus 0.0124 0.0197 0.1515
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0038 0.0045 0.0157
Loa Loa (eye worm) hypothetical protein 0.0077 0.0113 0.0393
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0077 0.0113 0.011
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0011 0.0066
Loa Loa (eye worm) intermediate filament protein 0.0083 0.0125 0.0434
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0261 0.044 0.3471
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0197 0.0195
Loa Loa (eye worm) hypothetical protein 0.0113 0.0178 0.062
Entamoeba histolytica calpain large subunit domain III containing protein 0.0019 0.0011 0.0052
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0124 0.0197 0.0195
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0064 0.0091 0.1051
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0038 0.0045 0.0829
Loa Loa (eye worm) hypothetical protein 0.0038 0.0045 0.0157
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0077 0.0113 0.0874
Onchocerca volvulus 0.0124 0.0197 0.1515
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0111
Trypanosoma brucei glucose transporter 2A 0.0032 0.0035 0.0547
Echinococcus multilocularis microtubule associated protein 2 0.5652 1 1
Loa Loa (eye worm) bromodomain containing protein 0.0055 0.0075 0.0259
Brugia malayi Smad1 0.0041 0.0051 0.0171
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0115 0.0181 0.0178
Schistosoma mansoni sugar transporter 0.0015 0.0003 0.0001
Echinococcus granulosus biogenic amine 5HT receptor 0.0244 0.041 0.041
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0261 0.044 0.153
Loa Loa (eye worm) G-protein coupled receptor 0.0124 0.0197 0.0685
Plasmodium vivax sugar transporter, putative 0.0015 0.0003 0.0024
Trichomonas vaginalis antibiotic synthetase, putative 0.0077 0.0113 0.0877
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.016 0.0261 0.5082
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.016 0.0261 0.4158
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0184 0.0304 0.2392
Schistosoma mansoni neuropeptide receptor 0.0124 0.0197 0.0195
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0032 0.0105
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0026 0.0023 0.0074
Brugia malayi hypothetical protein 0.0017 0.0008 0.0022
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0042 0.0345
Brugia malayi jmjC domain containing protein 0.0047 0.006 0.0203
Loa Loa (eye worm) ion channel NompC 0.0075 0.0111 0.0387
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0092
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0302 0.6781
Trypanosoma brucei protein kinase, putative 0.016 0.0261 0.4184
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0064 0.0091 0.0705
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.0016 0.0014
Echinococcus multilocularis potassium voltage gated channel protein 0.0075 0.0111 0.0108
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0261 0.044 0.9899
Loa Loa (eye worm) hypothetical protein 0.0113 0.0178 0.062
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0007 0.0003
Brugia malayi hypothetical protein 0.0075 0.0111 0.0381
Echinococcus granulosus allatostatin A receptor 0.0124 0.0197 0.0196
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0147 0.0239 0.0237
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0007 0.009
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0113 0.1455
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0012 0.0012
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.0158 0.0157
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0075 0.0111 0.2132
Onchocerca volvulus 0.0015 0.0003 0.0011
Onchocerca volvulus 0.0124 0.0197 0.1515
Onchocerca volvulus 0.0015 0.0003 0.0011
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Onchocerca volvulus 0.0083 0.0125 0.0954
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0035 0.0268
Loa Loa (eye worm) Ulp1 protease 0.0064 0.0091 0.0316
Brugia malayi RNA recognition motif domain containing protein 0.0202 0.0336 0.1163
Echinococcus granulosus caspase 3 0.0071 0.0102 0.0102
Loa Loa (eye worm) TAR-binding protein 0.0202 0.0336 0.1168
Echinococcus multilocularis tar DNA binding protein 0.0202 0.0336 0.0333
Onchocerca volvulus 0.0124 0.0197 0.1515
Echinococcus multilocularis transient receptor potential gamma protein 0.0269 0.0454 0.0451
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0094 0.0145 0.2792
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0261 0.044 0.9899
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Loa Loa (eye worm) carboxylesterase 0.0028 0.0026 0.0092
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0023 0.0179
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0077 0.0113 0.2491
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0115 0.0181 0.0631
Schistosoma mansoni zinc finger protein 0.0047 0.0062 0.006
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.0015 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0197 0.0194
Brugia malayi Bromodomain containing protein 0.0038 0.0046 0.0152
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0075 0.0111 0.0108
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0113 0.0112
Loa Loa (eye worm) isocitrate dehydrogenase 0.0048 0.0062 0.0217
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0094 0.0145 0.0143
Brugia malayi nuclear receptor NHR-88 0.0015 0.0003 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0032 0.0105
Loa Loa (eye worm) hypothetical protein 0.0193 0.0319 0.1111
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0003 0.0003
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0327 0.0557 0.0554
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0067 0.0066
Schistosoma mansoni biogenic amine receptor 0.0124 0.0197 0.0195
Loa Loa (eye worm) hypothetical protein 0.0136 0.0218 0.0758
Echinococcus multilocularis ferritin 0.0017 0.0007 0.0004
Echinococcus multilocularis transient receptor potential cation channel 0.0075 0.0111 0.0108
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.001 0.0029
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0075 0.0111 0.0109
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0032 0.0111
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0195 0.0323 0.2542
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0077 0.0113 0.0874
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Schistosoma mansoni smad 0.0041 0.0051 0.0049
Mycobacterium ulcerans carboxylesterase, LipT 0.0028 0.0026 0.0525
Onchocerca volvulus 0.0015 0.0003 0.0011
Echinococcus granulosus calpain 0.0019 0.0011 0.001
Leishmania major 4-coumarate:coa ligase-like protein 0.0261 0.044 0.391
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0124 0.0197 0.0194
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0011 0.0124
Loa Loa (eye worm) hypothetical protein 0.0308 0.0523 0.182
Schistosoma mansoni jumonji domain containing protein 0.0081 0.0121 0.0119
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0006 0.0015
Brugia malayi follicle stimulating hormone receptor 0.0124 0.0197 0.068
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0062 0.0087 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0196 0.1518
Loa Loa (eye worm) patched family protein 0.0017 0.0008 0.0028
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0124 0.0197 0.0194
Loa Loa (eye worm) latrophilin receptor protein 2 0.0193 0.0319 0.1111
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Schistosoma mansoni hypothetical protein 0.0838 0.1463 0.1461
Onchocerca volvulus 0.0015 0.0003 0.0011
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Schistosoma mansoni methyl-cpg binding protein mbd 0.0053 0.0071 0.0069
Echinococcus granulosus transient receptor potential cation channel 0.0075 0.0111 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0003 0.0026
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0007 0.0005
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0131 0.0209 0.336
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0045 0.0058 0.0055
Brugia malayi hypothetical protein 0.0016 0.0006 0.0015
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0124 0.0197 0.0685
Loa Loa (eye worm) Ulp1 protease 0.0064 0.0091 0.0316
Mycobacterium ulcerans acyl-CoA synthetase 0.0077 0.0113 0.2491
Mycobacterium ulcerans tryptophan-rich sensory protein 0.0263 0.0444 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0003 0.0011
Trypanosoma brucei glucose transporter, putative 0.0032 0.0035 0.0547
Schistosoma mansoni growth hormone secretagogue receptor 0.0124 0.0197 0.0195
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.0162 0.0161
Echinococcus multilocularis potassium voltage gated channel protein 0.0075 0.0111 0.0108
Schistosoma mansoni metabotropic glutamate receptor 0.0026 0.0024 0.0022
Schistosoma mansoni neuropeptide receptor 0.0124 0.0197 0.0195
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0032 0.0105
Echinococcus multilocularis voltage dependent calcium channel 0.0168 0.0275 0.0272
Schistosoma mansoni protein kinase 0.0038 0.0045 0.0043
Brugia malayi hypothetical protein 0.0028 0.0026 0.0086
Schistosoma mansoni Smad4 0.0019 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0495 0.0856 0.0853
Schistosoma mansoni peripheral-type benzodiazepine receptor 0.0263 0.0444 0.0442
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.0185 0.0182
Schistosoma mansoni hypothetical protein 0.0416 0.0716 0.0714
Echinococcus granulosus lamin dm0 0.0083 0.0125 0.0124
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0032 0.0403
Onchocerca volvulus 0.0124 0.0197 0.1515
Onchocerca volvulus 0.0124 0.0197 0.1515
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0014 0.0049
Brugia malayi hypothetical protein 0.002 0.0012 0.0036
Echinococcus multilocularis neuroligin 0.0028 0.0026 0.0023
Loa Loa (eye worm) calcium channel 0.0168 0.0275 0.0958
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0162 0.1254
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0075 0.0111 0.0111
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0011 0.012
Onchocerca volvulus 0.0077 0.0113 0.0864
Schistosoma mansoni sugar transporter 0.0015 0.0003 0.0001
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0023 0.0319
Schistosoma mansoni nuclear receptor 0.0015 0.0003 0.0001
Brugia malayi Muscleblind-like protein 0.0308 0.0523 0.1815
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0179
Echinococcus multilocularis calpain 7 (C02 family) 0.0019 0.0011 0.0008
Schistosoma mansoni smad 0.0019 0.001 0.0008
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0048 0.0062 0.047
Loa Loa (eye worm) hypothetical protein 0.0053 0.0072 0.025
Loa Loa (eye worm) hypothetical protein 0.0126 0.0202 0.0701
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0076 0.0111 0.0381
Loa Loa (eye worm) TYRA-2 protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) beta-lactamase 0.0113 0.0178 0.062
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0029
Echinococcus granulosus L aminoadipate semialdehyde 0.0167 0.0274 0.0274
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Echinococcus multilocularis zinc finger protein 0.0064 0.0091 0.0088
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0042 0.0665
Brugia malayi GTP-ase activating protein for Arf containing protein 0.003 0.0031 0.0102
Echinococcus granulosus solute carrier family 22 0.0015 0.0003 0.0003
Trypanosoma cruzi kinesin, putative 0.0019 0.0011 0.012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Loa Loa (eye worm) ctsf protein 0.0016 0.0007 0.0022
Echinococcus granulosus transient receptor potential cation channel 0.0075 0.0111 0.0111
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0112 0.0175 0.0172
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0113
Loa Loa (eye worm) hypothetical protein 0.0044 0.0056 0.0195
Schistosoma mansoni 60S ribosomal protein L21 0.0075 0.0111 0.0109
Schistosoma mansoni hypothetical protein 0.0119 0.0188 0.0186
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0075 0.0111 0.0108
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0167 0.0274 0.0949
Brugia malayi Receptor family ligand binding region containing protein 0.0014 0.0002 0.0001
Schistosoma mansoni cpg binding protein 0.0065 0.0093 0.0091
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0035 0.0268
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0168 0.0275 0.0272
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Echinococcus granulosus voltage gated potassium channel 0.0075 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0075 0.0111 0.085
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0011 0.0168
Trichomonas vaginalis spcc417.12 protein, putative 0.0028 0.0026 0.0205
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0035 0.0268
Loa Loa (eye worm) MH2 domain-containing protein 0.0609 0.1057 0.3678
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0032 0.003
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0073 0.0107 0.0105
Leishmania major C-8 sterol isomerase-like protein 0.0364 0.0622 0.5546
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Echinococcus granulosus p2X purinoceptor 4 0.0134 0.0215 0.0214
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0019 0.0017
Echinococcus granulosus mitogen activated protein kinase 11 0.0253 0.0427 0.0426
Echinococcus multilocularis translocator protein 0.0263 0.0444 0.0441
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0075 0.0111 0.1745
Echinococcus multilocularis mitogen activated protein kinase 14 0.0253 0.0427 0.0424
Toxoplasma gondii patched family protein 0.0017 0.0008 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0011 0.012
Plasmodium vivax CDK-related protein kinase 6, putative 0.0448 0.0771 1
Trichomonas vaginalis sentrin/sumo-specific protease, senp8, putative 0.0064 0.0091 0.0705
Echinococcus multilocularis voltage dependent calcium channel 0.0168 0.0275 0.0272
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0077 0.0262
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0077 0.0113 0.0984
Loa Loa (eye worm) hypothetical protein 0.0039 0.0046 0.0159
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0032 0.0105
Loa Loa (eye worm) MH1 domain-containing protein 0.0041 0.0051 0.0177
Mycobacterium ulcerans acyl-CoA synthetase 0.0077 0.0113 0.2491
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0007 0.0031
Echinococcus multilocularis calpain 5 0.0019 0.0011 0.0008
Brugia malayi Isocitrate dehydrogenase 0.0048 0.0062 0.0211
Brugia malayi hypothetical protein 0.0017 0.0008 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Loa Loa (eye worm) hypothetical protein 0.0083 0.0125 0.0434
Echinococcus granulosus calpain A 0.0019 0.0011 0.001
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0033 0.0032
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0064 0.0091 0.0705
Loa Loa (eye worm) hypothetical protein 0.0082 0.0122 0.0424
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0064 0.0091 0.1051
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0124 0.0197 0.0195
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0077 0.0113 0.0393
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0197 0.0196
Mycobacterium ulcerans hypothetical protein 0.0113 0.0178 0.3967
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0077 0.0113 0.0874
Loa Loa (eye worm) hypothetical protein 0.0063 0.0089 0.0311
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0168 0.0275 0.0272
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0033 0.0588
Schistosoma mansoni glucose transporter 0.0015 0.0003 0.0001
Brugia malayi Cathepsin L-like precursor 0.0016 0.0007 0.0016
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0015 0.0114
Mycobacterium ulcerans acyl-CoA synthetase 0.0077 0.0113 0.2491
Onchocerca volvulus 0.0124 0.0197 0.1515
Onchocerca volvulus 0.0124 0.0197 0.1515
Schistosoma mansoni methyl-cpg binding protein mbd 0.0053 0.0071 0.0069
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Echinococcus granulosus mitogen activated protein kinase 3 0.016 0.0261 0.026
Brugia malayi beta-lactamase 0.0113 0.0178 0.0614
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.001 0.001
Brugia malayi beta-lactamase family protein 0.0113 0.0178 0.0614
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0301 0.0297
Brugia malayi hypothetical protein 0.0124 0.0197 0.068
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0075 0.0111 0.0109
Echinococcus granulosus 7tm_1 domain containing protein 0.0124 0.0197 0.0196
Echinococcus multilocularis sentrin specific protease 1 0.0097 0.015 0.0147
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0032 0.003
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0305 0.0518 0.6375
Brugia malayi hypothetical protein 0.0124 0.0197 0.068
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0124 0.0197 0.0195
Loa Loa (eye worm) patched family protein 0.0017 0.0008 0.0028
Mycobacterium tuberculosis Probable hydrolase 0.0113 0.0178 0.1391
Echinococcus multilocularis neuropeptides capa receptor 0.0124 0.0197 0.0194
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0022
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0124 0.0197 0.0196
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0055 0.0186
Onchocerca volvulus 0.0094 0.0145 0.1109
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0023 0.039
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0038 0.0045 0.0157
Plasmodium falciparum calcium-dependent protein kinase 3 0.0038 0.0045 0.057
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0253 0.0427 0.1485
Echinococcus multilocularis calcium activated potassium channel 0.0084 0.0126 0.0123
Echinococcus granulosus muscleblind protein 0.0308 0.0523 0.0522
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0041 0.0051 0.0048
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0149 0.0242 0.1897
Trypanosoma brucei metacaspase 5, putative 0.0026 0.0023 0.0362
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.0178 0.0176
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Loa Loa (eye worm) MH2 domain-containing protein 0.0041 0.0051 0.0177
Brugia malayi AMP-binding enzyme family protein 0.0261 0.044 0.1525
Loa Loa (eye worm) carboxylesterase 0.0028 0.0026 0.0092
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0007 0.0016
Brugia malayi MH1 domain containing protein 0.0041 0.0051 0.0171
Brugia malayi TspO/MBR family protein 0.0263 0.0444 0.154
Onchocerca volvulus 0.0124 0.0197 0.1515
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0183 0.0302 0.0299
Echinococcus granulosus translocator protein 0.0263 0.0444 0.0443
Schistosoma mansoni hypothetical protein 0.0238 0.04 0.0398
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0261 0.2021
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0042 0.0623
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Echinococcus granulosus voltage gated potassium channel 0.0075 0.0111 0.0111
Onchocerca volvulus 0.0015 0.0003 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0202 0.0336 0.0334
Brugia malayi CHE-14 protein 0.0123 0.0196 0.0675
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0075 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0077 0.0113 0.0395
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0019 0.0296
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0077 0.0113 0.2168
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0033 0.0107
Echinococcus multilocularis mitogen activated protein kinase 0.016 0.0261 0.0257
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0003 0.0005
Brugia malayi protein C24B5.3 0.0017 0.0008 0.0022
Echinococcus multilocularis calpain family protein 1, d 0.0044 0.0056 0.0053
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0062 0.053
Echinococcus granulosus neuropeptide receptor A26 0.1501 0.264 0.2639
Brugia malayi intermediate filament protein 0.0083 0.0125 0.0428
Plasmodium falciparum phd finger protein, putative 0.0031 0.0032 0.0403
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0113 0.3121
Echinococcus granulosus Niemann Pick C1 protein 0.041 0.0704 0.0704
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0261 0.2021
Leishmania major DNA polymerase kappa, putative 0.0019 0.0011 0.0069
Brugia malayi RNA binding protein 0.0202 0.0336 0.1163
Mycobacterium leprae conserved hypothetical protein 0.0047 0.0061 0.1241
Echinococcus granulosus Niemann Pick C1 protein 0.0287 0.0486 0.0486
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Schistosoma mansoni zinc finger protein 0.0015 0.0003 0.0001
Echinococcus multilocularis voltage gated potassium channel 0.0075 0.0111 0.0108
Onchocerca volvulus 0.0017 0.0008 0.005
Schistosoma mansoni hypothetical protein 0.0399 0.0685 0.0683
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0077 0.0074
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.0015 0.0014
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0077 0.0113 0.2491
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0042 0.0051 0.0644
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.008
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.065 0.1131 0.3935
Plasmodium falciparum acyl-CoA synthetase 0.0195 0.0323 0.4174
Schistosoma mansoni rab6-interacting 0.002 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0035 0.0505
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0023 0.0179
Echinococcus multilocularis hyperpolarization activated cyclic 0.0075 0.0111 0.0108
Echinococcus granulosus g-protein coupled receptor 0.0124 0.0197 0.0196
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0062 0.0059
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0261 0.044 0.9899
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0011 0.0124
Entamoeba histolytica Arf GTPase activating protein, putative 0.0029 0.0029 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0179
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0015 0.0102
Onchocerca volvulus 0.074 0.129 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0032 0.0031
Echinococcus multilocularis General substrate transporter 0.0089 0.0136 0.0133
Loa Loa (eye worm) hypothetical protein 0.0219 0.0367 0.1276
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0012 0.0009
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0067 0.0503
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Loa Loa (eye worm) PHD-finger family protein 0.0064 0.0091 0.0316
Echinococcus granulosus caspase 8 0.0026 0.0023 0.0022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0077 0.0113 0.0874
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.0162 0.0161
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0097 0.015 0.0148
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0003 0.0003
Onchocerca volvulus Neuropeptide F receptor homolog 0.0124 0.0197 0.1515
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0077 0.0113 0.2448
Loa Loa (eye worm) hypothetical protein 0.0416 0.0716 0.2491
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Brugia malayi hypothetical protein 0.015 0.0243 0.0839
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0075 0.0111 0.0381
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Brugia malayi hypothetical protein 0.0017 0.0008 0.0022
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0011 0.0061
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0387
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0006 0.0015
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.001 0.0035
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0015 0.0225
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0184 0.0304 0.2392
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0077 0.0113 0.1811
Echinococcus granulosus transient receptor potential cation channel 0.0075 0.0111 0.0111
Echinococcus multilocularis two pore calcium channel protein 1 0.0075 0.0111 0.0108
Echinococcus granulosus neuropeptide Y receptor 0.0124 0.0197 0.0196
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0015 0.0184
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0301 0.0299
Brugia malayi voltage-dependent calcium channel 0.0075 0.0111 0.0381
Brugia malayi P38 map kinase family protein 2 0.0253 0.0427 0.148
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0075 0.0111 0.0109
Onchocerca volvulus 0.0016 0.0007 0.0036
Echinococcus granulosus hypothetical protein 0.0075 0.0111 0.0111
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0007 0.0022
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0015 0.0114
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0113 0.0178 0.062
Echinococcus multilocularis Niemann Pick C1 protein 0.041 0.0704 0.0701
Echinococcus granulosus neuroligin 0.0028 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0164 0.0268 0.0932
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0075 0.0111 0.0381
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0047 0.0061 0.1307
Leishmania major DNA polymerase eta, putative 0.0031 0.0032 0.0258
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0113 0.2176
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0042 0.0623
Brugia malayi Tachykinin-like peptides receptor 99D 0.0124 0.0197 0.068
Trypanosoma brucei kinesin, putative 0.0019 0.0011 0.0163
Mycobacterium ulcerans acyl-CoA synthetase 0.0077 0.0113 0.2491
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0022
Entamoeba histolytica protein kinase, putative 0.0038 0.0045 0.0482
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0075 0.0111 0.0381
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0047 0.0061 0.0458
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0104 0.0162 0.0159
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Trypanosoma brucei hypothetical protein, conserved 0.0047 0.0061 0.0971
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0011 0.0174
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Brugia malayi Cathepsin L-like precursor 0.0016 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.004
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0032 0.0031
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Schistosoma mansoni protein kinase 0.0038 0.0045 0.0043
Loa Loa (eye worm) hypothetical protein 0.1168 0.2049 0.7133
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0183 0.0302 0.0302
Onchocerca volvulus 0.0238 0.04 0.3092
Plasmodium falciparum calcium-dependent protein kinase 1 0.0038 0.0045 0.057
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Echinococcus granulosus hyperpolarization activated cyclic 0.0075 0.0111 0.0111
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0124 0.0197 0.0196
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0003 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0091 0.0705
Brugia malayi neuropeptide F receptor 0.0124 0.0197 0.068
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0635 0.1103 0.11
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0092
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0077 0.0113 0.0387
Giardia lamblia Fructose-bisphosphate aldolase 0.0305 0.0518 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0032 0.0029
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0011 0.0055
Schistosoma mansoni polycystin 1-related 0.002 0.0012 0.001
Onchocerca volvulus 0.0263 0.0444 0.3433
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0088 0.1413
Echinococcus multilocularis GPCR, family 2 0.0193 0.0319 0.0316
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0124 0.0197 0.0194
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0033 0.0326
Loa Loa (eye worm) hypothetical protein 0.0186 0.0307 0.1068
Echinococcus multilocularis smad 0.0041 0.0051 0.0048
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0062 0.0059
Echinococcus multilocularis hyperpolarization activated cyclic 0.0075 0.0111 0.0108
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0077 0.0113 0.0874
Echinococcus multilocularis Niemann Pick C1 protein 0.0287 0.0486 0.0483
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0011 0.0011
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0088 0.1375
Echinococcus multilocularis expressed protein 0.0017 0.0007 0.0004
Entamoeba histolytica hypothetical protein 0.015 0.0243 0.2943
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0011 0.0008
Onchocerca volvulus 0.0113 0.0178 0.1369
Schistosoma mansoni neuropeptide f receptor 76f 0.0124 0.0197 0.0195
Brugia malayi AMP-binding enzyme family protein 0.0261 0.044 0.1525
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0011 0.0168
Echinococcus granulosus tm gpcr rhodopsin 0.0941 0.1647 0.1646
Brugia malayi nuclear receptor RXR 0.0016 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0261 0.044 0.153
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0075 0.0111 0.0108
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0023 0.0179
Schistosoma mansoni vesicular amine transporter 0.0075 0.0111 0.0109
Plasmodium vivax acyl-CoA synthetase, putative 0.0195 0.0323 0.4174
Echinococcus granulosus geminin 0.0838 0.1463 0.1462
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0003 0.0005
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0007 0.0003
Echinococcus granulosus dnaJ subfamily B 0.0399 0.0685 0.0684
Brugia malayi Calcitonin receptor-like protein seb-1 0.0609 0.1058 0.3677
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0032 0.0031
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.0518 0.402
Echinococcus granulosus expressed conserved protein 0.0405 0.0696 0.0695
Loa Loa (eye worm) calpain 5 0.0019 0.0011 0.0037
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0124 0.0197 0.0685
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0003 0.0003
Echinococcus multilocularis protein patched 0.0123 0.0196 0.0193
Onchocerca volvulus 0.0015 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Schistosoma mansoni transient receptor potential channel 0.0269 0.0454 0.0452
Brugia malayi hypothetical protein 0.0015 0.0003 0.0005
Schistosoma mansoni acetyl-CoA synthetase 0.0077 0.0113 0.0111
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0077 0.0661
Echinococcus multilocularis L aminoadipate semialdehyde 0.0167 0.0274 0.0271
Echinococcus granulosus neuropeptide FF receptor 2 0.0124 0.0197 0.0196
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.008
Echinococcus multilocularis RUN 0.002 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Echinococcus granulosus solute carrier family 22 0.0015 0.0003 0.0003
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0055 0.084
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0022
Onchocerca volvulus 0.0016 0.0007 0.0036
Echinococcus granulosus acetylcholinesterase 0.0164 0.0268 0.0267
Loa Loa (eye worm) acetylcholinesterase 1 0.0164 0.0268 0.0932
Echinococcus granulosus RUN 0.002 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0007 0.0051
Trypanosoma brucei glucose transporter, putative 0.0032 0.0035 0.0547
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Brugia malayi Myosin head containing protein 0.0017 0.0008 0.0022
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0019 0.0301
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0006 0.0004
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0007 0.0066
Loa Loa (eye worm) hypothetical protein 0.0105 0.0163 0.0566
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0533 0.0922 0.3208
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0064 0.0091 0.0785
Schistosoma mansoni voltage-gated cation channel 0.0168 0.0275 0.0273
Brugia malayi Transient-receptor-potential like protein 0.0143 0.0231 0.0799
Echinococcus multilocularis cysteine protease 0.0016 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0124 0.0197 0.0195
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.0158 0.0155
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0124 0.0197 0.0685
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0032 0.0029
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0075 0.0111 0.0109
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0075 0.0111 0.0109
Brugia malayi nuclear receptor NHR-88 0.0031 0.0032 0.0105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0032 0.0111
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0416 0.0715 0.0713
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0064
Entamoeba histolytica hypothetical protein 0.015 0.0243 0.2943
Schistosoma mansoni hypothetical protein 0.0193 0.0319 0.0317
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0012 0.0072
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.0178 0.2826
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0032 0.0105
Leishmania major acetyl-CoA synthetase, putative 0.0077 0.0113 0.0984
Echinococcus granulosus neuropeptides capa receptor 0.0124 0.0197 0.0196
Schistosoma mansoni ap endonuclease 0.0056 0.0077 0.0075
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0075 0.0111 0.0111
Brugia malayi Cell death protein 3 precursor 0.0026 0.0023 0.0074
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0003 0.0001
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0062 0.1167
Plasmodium vivax vivapain-2 0.0016 0.0007 0.0066
Echinococcus multilocularis acetylcholinesterase 0.0164 0.0268 0.0265
Schistosoma mansoni neuropeptide F-like receptor 0.0124 0.0197 0.0195
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0035 0.0547
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0193 0.0319 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0007 0.0051
Brugia malayi AMP-binding enzyme family protein 0.0077 0.0113 0.0387
Echinococcus granulosus sentrin specific protease 8 0.0064 0.0091 0.009
Entamoeba histolytica hypothetical protein 0.0047 0.0061 0.0677
Echinococcus granulosus peptide allatostatin:somatostatin 0.0124 0.0197 0.0196
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0007 0.009
Echinococcus multilocularis mitogen activated protein kinase 14 0.0253 0.0427 0.0424
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0197 0.0194
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0077 0.0598
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0261 0.2021
Onchocerca volvulus 0.0015 0.0003 0.001
Toxoplasma gondii cathepsin CPL 0.0016 0.0007 0.0064
Schistosoma mansoni neuropeptide receptor 0.0124 0.0197 0.0195
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0174 0.0287 0.3706
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Toxoplasma gondii hypothetical protein 0.0017 0.0008 0.01
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0088 0.1413
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0197 0.0196
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0019 0.0345
Toxoplasma gondii propionate-CoA ligase 0.0077 0.0113 0.2168
Brugia malayi hypothetical protein 0.1168 0.2049 0.7131
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Brugia malayi PHD-finger family protein 0.0019 0.0012 0.0034
Brugia malayi olfactory channel protein osm-9 0.0075 0.0111 0.0381
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0067 0.0503
Brugia malayi hypothetical protein 0.0124 0.0197 0.068
Echinococcus multilocularis p2X purinoceptor 4 0.0134 0.0215 0.0212
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0193 0.0319 0.0319
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0033 0.0031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0145 0.0143
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.016 0.0261 0.0907
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0032 0.0466
Brugia malayi Dopamine receptor 0.0124 0.0197 0.068
Echinococcus granulosus transient receptor potential cation channel 0.0075 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) cysteine protease 0.0016 0.0007 0.0022
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.0162 0.0159
Onchocerca volvulus Protein patched homolog 0.0017 0.0008 0.005
Echinococcus multilocularis orexin receptor type 2 0.0124 0.0197 0.0194
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0019 0.0017
Onchocerca volvulus Cell death protein 3 homolog 0.0026 0.0023 0.0165
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0075 0.0111 0.0863
Mycobacterium leprae conserved hypothetical protein 0.0113 0.0178 0.3953
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0111
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0042
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Brugia malayi calpain family protein 1 0.0063 0.0089 0.0305
Trypanosoma brucei glucose transporter, putative 0.0032 0.0035 0.0547
Echinococcus multilocularis ryanodine receptor 44f 0.0076 0.0111 0.0108
Brugia malayi hypothetical protein 0.0015 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0533 0.0922 0.3208
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.0162 0.0159
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0011 0.012
Echinococcus multilocularis voltage gated potassium channel 0.0075 0.0111 0.0108
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0261 0.044 0.3471
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0007 0.0052
Brugia malayi Dopamine receptor protein 1 0.0533 0.0922 0.3204
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0075 0.0111 0.0387
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0038 0.0045 0.0042
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0149 0.0242 0.5409
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0077 0.0113 0.2491
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0012 0.0009
Onchocerca volvulus 0.0016 0.0007 0.0036
Echinococcus multilocularis sex peptide receptor 0.0124 0.0197 0.0194
Echinococcus granulosus potassium voltage gated channel protein 0.0075 0.0111 0.0111
Schistosoma mansoni transcription factor LCR-F1 0.015 0.0243 0.0241
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0124 0.0197 0.0195
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0075 0.0111 0.0863
Loa Loa (eye worm) melatonin receptor type 1A 0.0124 0.0197 0.0685
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0113 0.0178 0.0614
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.0518 0.402
Echinococcus granulosus p2X purinoceptor 4 0.0134 0.0215 0.0214
Echinococcus granulosus g protein coupled receptor 0.0124 0.0197 0.0196
Schistosoma mansoni cpg binding protein 0.0065 0.0093 0.0091
Echinococcus granulosus calpain 7 C02 family 0.0019 0.0011 0.001
Echinococcus granulosus fetal alzheimer antigen falz 0.0073 0.0107 0.0107
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0064 0.0091 0.031
Loa Loa (eye worm) ryanodine receptor 0.0075 0.0111 0.0387
Brugia malayi Sugar transporter family protein 0.0015 0.0003 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0032 0.0105
Onchocerca volvulus 0.0015 0.0003 0.0011
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0007 0.0006
Echinococcus multilocularis transient receptor potential cation channel 0.0075 0.0111 0.0108
Schistosoma mansoni hypothetical protein 0.0104 0.0162 0.016
Echinococcus granulosus tm gpcr rhodopsin 0.0635 0.1103 0.1102
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0123 0.0196 0.0681
Onchocerca volvulus 0.0077 0.0113 0.0864
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0124 0.0197 0.0194
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0197 0.0195
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0124 0.0197 0.068
Echinococcus granulosus transient receptor potential gamma protein 0.0269 0.0454 0.0453
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.0178 0.1382
Onchocerca volvulus 0.0017 0.0008 0.005
Mycobacterium tuberculosis Probable esterase LipL 0.0113 0.0178 0.1391
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0032 0.0031
Brugia malayi hypothetical protein 0.0124 0.0197 0.068
Onchocerca volvulus 0.0044 0.0056 0.0421
Schistosoma mansoni aldehyde dehydrogenase 0.0183 0.0302 0.03
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0003 0.0005
Echinococcus granulosus cpg binding protein 0.0065 0.0093 0.0093
Echinococcus granulosus sterol regulatory element binding protein 0.0123 0.0196 0.0195
Leishmania major hypothetical protein, unknown function 0.0075 0.0111 0.0968
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0168 0.0275 0.0952
Echinococcus granulosus voltage gated hydrogen channel 1 0.0075 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Trypanosoma brucei glucose transporter, putative 0.0032 0.0035 0.0547
Echinococcus multilocularis fmrfamide receptor 0.0124 0.0197 0.0194
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.001
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0075 0.0111 0.0109
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0032 0.0235
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0253 0.0427 0.6859
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0077 0.0113 0.1774
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0011 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0007 0.0051
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Echinococcus granulosus metabotropic glutamate receptor 5 0.0067 0.0096 0.0095
Echinococcus multilocularis G-protein coupled receptor, putative 0.0124 0.0197 0.0194
Echinococcus granulosus cathepsin l1 0.0016 0.0007 0.0006
Toxoplasma gondii patched family protein 0.0017 0.0008 0.0098
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Schistosoma mansoni survival motor neuron protein 0.0238 0.04 0.0398
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.001 0.0035
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Onchocerca volvulus 0.0064 0.0091 0.0692
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0023 0.0179
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0021 0.0015 0.0172
Echinococcus granulosus solute carrier family 22 0.0015 0.0003 0.0003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0011 0.0066
Echinococcus granulosus TRP transient receptor potential channel 0.0143 0.0231 0.0231
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.0015 0.0012
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0075 0.0111 0.0968
Brugia malayi Patched related family protein 12 0.0017 0.0008 0.0022
Echinococcus multilocularis shaker cognate 0.0075 0.0111 0.0108
Schistosoma mansoni hypothetical protein 0.0193 0.0319 0.0317
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0261 0.044 1
Brugia malayi PHD-finger family protein 0.0031 0.0032 0.0107
Loa Loa (eye worm) neuropeptide F receptor 0.0124 0.0197 0.0685
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0077 0.0113 0.0393
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0174 0.0287 0.5597
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0032 0.0105
Loa Loa (eye worm) hypothetical protein 0.0113 0.0178 0.062
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0075 0.0111 0.0111
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0124 0.0197 0.068
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0088 0.1375
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0077 0.0113 0.1774
Schistosoma mansoni cellular tumor antigen P53 0.0105 0.0163 0.0161
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0075 0.0111 0.0111
Mycobacterium tuberculosis Probable lipase LipE 0.0113 0.0178 0.1391
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0007 0.0051
Onchocerca volvulus 0.0077 0.0113 0.0864
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Loa Loa (eye worm) glutamate receptor 0.0054 0.0073 0.0255
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0124 0.0197 0.0194
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.0095 0.0093
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0037 0.0042 0.0042
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0064 0.0091 0.0705
Brugia malayi MH1 domain containing protein 0.0041 0.0051 0.0171
Onchocerca volvulus Protein patched homolog 0.0017 0.0008 0.005
Brugia malayi calpain 7 0.0019 0.0011 0.0031
Echinococcus multilocularis sodium leak channel non selective protein 0.0075 0.0111 0.0108
Loa Loa (eye worm) hypothetical protein 0.0244 0.041 0.1427
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0032 0.0105
Echinococcus multilocularis transient receptor potential cation channel 0.0075 0.0111 0.0108
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0124 0.0197 0.0195
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.016 0.0261 0.4158
Schistosoma mansoni hypothetical protein 0.0119 0.0188 0.0186
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0195 0.0323 0.7248
Echinococcus multilocularis G protein coupled receptor 139 0.0124 0.0197 0.0194
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0014 0.0002 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0197 0.0196
Loa Loa (eye worm) hypothetical protein 0.0115 0.0181 0.0631
Onchocerca volvulus 0.0083 0.0125 0.0954
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0032 0.003
Echinococcus granulosus G protein coupled receptor 139 0.0124 0.0197 0.0196
Echinococcus granulosus histone lysine methyltransferase setb 0.0147 0.0239 0.0238
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Echinococcus granulosus potassium voltage gated channel protein 0.0075 0.0111 0.0111
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.0178 0.1382
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0047 0.0061 0.1137
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0067 0.0096 0.0092
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0032 0.0576
Schistosoma mansoni hypothetical protein 0.0124 0.0197 0.0195
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0185 0.3592
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0032 0.0105
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0007 0.0066
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0075 0.0111 0.0108
Schistosoma mansoni hypothetical protein 0.0124 0.0197 0.0195
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0263 0.0444 0.1545
Echinococcus granulosus g protein coupled receptor 0.0124 0.0197 0.0196
Loa Loa (eye worm) hypothetical protein 0.0063 0.0089 0.0311
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1633 0.2873 1
Schistosoma mansoni voltage-dependent calcium channel 0.0075 0.0111 0.0109
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.0015 0.0051
Plasmodium falciparum sentrin-specific protease 1 0.0097 0.015 0.1927
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0011 0.012
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0032 0.003
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0253 0.0427 0.6845
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0197 0.0196
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0113 0.0113
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.0185 0.0185
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0014 0.0011
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0064 0.0091 0.0705
Brugia malayi conserved hypotetical protein 0.0015 0.0003 0.0005
Echinococcus multilocularis neuropeptide FF receptor 2 0.0124 0.0197 0.0194
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0023 0.0179
Brugia malayi Probable ClpP-like protease 0.0077 0.0113 0.0389
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0075 0.0111 0.1781
Schistosoma mansoni coup transcription factor 0.0031 0.0032 0.003
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0019 0.0345
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0075 0.0111 0.0111
Plasmodium falciparum lipid/sterol:H+ symporter 0.0017 0.0008 0.0088
Loa Loa (eye worm) hypothetical protein 0.0044 0.0056 0.0195
Toxoplasma gondii ABC1 family protein 0.0113 0.0178 0.3454
Mycobacterium ulcerans acyl-CoA synthetase 0.0077 0.0113 0.2491
Echinococcus granulosus smad 0.0041 0.0051 0.005
Trichomonas vaginalis esterase, putative 0.0113 0.0178 0.1382
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0077 0.1231
Echinococcus granulosus alpha 1A adrenergic receptor 0.0124 0.0197 0.0196
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Echinococcus multilocularis sterol regulatory element binding protein 0.0123 0.0196 0.0193
Leishmania major kinesin, putative 0.0019 0.0011 0.0066
Toxoplasma gondii transporter, cation channel family protein 0.0075 0.0111 0.2132
Echinococcus granulosus potassium large conductance calcium activated 0.0075 0.0111 0.0111
Schistosoma mansoni ferritin 0.0017 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0123 0.0196 0.0681
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0179
Schistosoma mansoni calpain (C02 family) 0.0019 0.0011 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0697 0.1213 0.9409
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0032 0.0111
Schistosoma mansoni Smad4 0.0041 0.0051 0.0049
Schistosoma mansoni lipoxygenase 0.0082 0.0123 0.0121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.0518 0.402
Loa Loa (eye worm) nuclear factor I 0.0023 0.0018 0.0063
Schistosoma mansoni hypothetical protein 0.0124 0.0197 0.0195
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0011 0.0009
Brugia malayi Patched family protein 0.0017 0.0008 0.0022
Brugia malayi GnHR receptor homolog 0.0124 0.0197 0.068
Echinococcus granulosus 7TM GPCR rhodopsin 0.0124 0.0197 0.0196
Brugia malayi Serotonin receptor 0.0578 0.1002 0.3485
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0077 0.0113 0.2448
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0035 0.0268
Echinococcus granulosus mitogen activated protein kinase 0.016 0.0261 0.026
Loa Loa (eye worm) hypothetical protein 0.0609 0.1058 0.3681
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0035 0.0268
Plasmodium vivax SET domain protein, putative 0.0094 0.0145 0.1861
Entamoeba histolytica hypothetical protein 0.0023 0.0019 0.0149
Leishmania major cathepsin L-like protease 0.0016 0.0007 0.0029
Onchocerca volvulus 0.0124 0.0197 0.1515
Trypanosoma brucei metacaspase MCA3 0.0026 0.0023 0.0362
Onchocerca volvulus 0.0015 0.0003 0.0011
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0064 0.0091 0.0705
Echinococcus multilocularis potassium voltage gated channel protein 0.0075 0.0111 0.0108
Schistosoma mansoni amine GPCR 0.0451 0.0777 0.0775
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0327 0.0557 0.0555
Schistosoma mansoni DNA helicase recq1 0.0021 0.0015 0.0013
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0064 0.0091 0.1051
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0024 0.0296
Schistosoma mansoni P2X receptor subunit 0.0134 0.0215 0.0213
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0075 0.0111 0.0111
Onchocerca volvulus 0.002 0.0012 0.008
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0083 0.0125 0.0434
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0193 0.0319 0.0316
Schistosoma mansoni hypothetical protein 0.0075 0.0111 0.0109
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0019 0.0058
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0111 0.0109
Mycobacterium ulcerans esterase/lipase LipP 0.0113 0.0178 0.3967
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0032 0.0029
Onchocerca volvulus 0.0015 0.0003 0.0011
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0003 0.0026
Brugia malayi PHD-finger family protein 0.0081 0.012 0.0412
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0026 0.0023 0.0021
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0077 0.6696
Giardia lamblia Sgs1 DNA helicase, putative 0.0021 0.0015 0.0221
Echinococcus multilocularis muscleblind protein 1 0.0308 0.0523 0.052
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0033 0.003
Brugia malayi AKH receptor 0.0124 0.0197 0.068
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0028
Echinococcus granulosus lysine specific demethylase 5A 0.0047 0.006 0.006
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0112 0.0175 0.0175
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0077 0.0113 0.2491
Schistosoma mansoni neuroligin 3 (S09 family) 0.0028 0.0026 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0011 0.0168
Brugia malayi hypothetical protein 0.0015 0.0003 0.0005
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0124 0.0197 0.0196
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0075 0.0111 0.0381
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0113
Schistosoma mansoni transient receptor potential channel 0.0201 0.0334 0.0332
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0023 0.0179
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0124 0.0197 0.0685
Schistosoma mansoni P2X receptor subunit 0.0134 0.0215 0.0213
Loa Loa (eye worm) hypothetical protein 0.0023 0.0018 0.0063
Plasmodium vivax calcium-dependent protein kinase, putative 0.0038 0.0045 0.057
Schistosoma mansoni ferritin light chain 0.0017 0.0007 0.0005
Brugia malayi hypothetical protein 0.0016 0.0006 0.0015
Brugia malayi Cathepsin L-like precursor 0.0016 0.0007 0.0016
Schistosoma mansoni nuclear receptor 0.0015 0.0003 0.0001
Brugia malayi Metabotropic glutamate receptor precursor. 0.0054 0.0073 0.0249
Loa Loa (eye worm) hypothetical protein 0.0124 0.0197 0.0685
Leishmania major pantothenate kinase subunit, putative 0.0022 0.0016 0.0117
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0011 0.0008
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0682 0.1186 0.1185
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0015 0.0114
Leishmania major glucose transporter, lmgt1 0.0032 0.0035 0.028
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0032 0.0235
Brugia malayi putative neuropeptide receptor 0.0124 0.0197 0.068
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0014 0.0105
Onchocerca volvulus 0.0105 0.0163 0.125
Echinococcus multilocularis neuropeptide s receptor 0.1501 0.264 0.2637
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0007 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0045 0.0351
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0291 0.0494 0.0492
Loa Loa (eye worm) patched family protein 0.0017 0.0008 0.0028
Schistosoma mansoni DNA polymerase eta 0.0044 0.0055 0.0053
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0124 0.0197 0.0196
Brugia malayi MH2 domain containing protein 0.0041 0.0051 0.0171
Loa Loa (eye worm) hypothetical protein 0.0287 0.0486 0.1692
Loa Loa (eye worm) hypothetical protein 0.0113 0.0178 0.062
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0028 0.0026 0.0184
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0183 0.0302 0.2679

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.35 uM Inhibition of electric eel AChE by Ellman's method ChEMBL. 19243862
IC50 (binding) = 6.76 uM Inhibition of equine serum BuChE by Ellman's method ChEMBL. 19243862

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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