Detailed information for compound 1133736

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 469.944 | Formula: C22H20ClN5O3S
  • H donors: 1 H acceptors: 5 LogP: 3.94 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)CN(S(=O)(=O)c1ccc(cc1)Cl)Cc1ccc(cc1)c1[nH]nnn1
  • InChi: 1S/C22H20ClN5O3S/c1-31-20-10-4-17(5-11-20)15-28(32(29,30)21-12-8-19(23)9-13-21)14-16-2-6-18(7-3-16)22-24-26-27-25-22/h2-13H,14-15H2,1H3,(H,24,25,26,27)
  • InChiKey: FBAYADNKOSZSNU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens chemokine (C-X-C motif) receptor 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0012 0.0057
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0116 0.0194 0.4095
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0257 0.0473 0.178
Brugia malayi dehydrogenases, short chain protein 2 0.0019 0.0003 0.0014
Echinococcus multilocularis lamin 0.0055 0.0074 0.0074
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0044 0.0179
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0006 0.0031
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0037 0.0148
Echinococcus multilocularis peregrin 0.0038 0.004 0.004
Brugia malayi Glycosyl hydrolases family 31 protein 0.0182 0.0325 0.1594
Loa Loa (eye worm) hypothetical protein 0.0055 0.0074 0.0364
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0003 0.0009
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0019 0.0003 0.001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0397 0.0752 0.3687
Loa Loa (eye worm) hypothetical protein 0.0072 0.0107 0.0525
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0006 0.0132
Mycobacterium ulcerans hypothetical protein 0.0072 0.0107 0.0389
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0084
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Mycobacterium tuberculosis Probable peptidase 0.0027 0.0018 0.0057
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0021 0.0078
Schistosoma mansoni inositol monophosphatase 0.0037 0.0037 0.014
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0044 0.0179
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0257 0.0473 0.178
Brugia malayi beta-lactamase family protein 0.0257 0.0473 0.2322
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0003 0.0059
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0035 0.0541
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.004 0.0044 0.0937
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0057
Schistosoma mansoni tar DNA-binding protein 0.0195 0.0352 0.1322
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0014
Schistosoma mansoni nuclear receptor 0.0024 0.0012 0.0043
Schistosoma mansoni nuclear receptor 0.0024 0.0012 0.0043
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0012 0.0043
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.034 0.0637 0.0637
Mycobacterium ulcerans beta-lactamase 0.0257 0.0473 0.1722
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0012 0.0012
Loa Loa (eye worm) prolyl oligopeptidase 0.0027 0.0018 0.009
Echinococcus granulosus tar DNA binding protein 0.0195 0.0352 0.1322
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0003 0.0059
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0051 0.0064 0.0064
Mycobacterium leprae Probable lipase LipE 0.0257 0.0473 0.1722
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0003 0.001
Brugia malayi ecdysteroid receptor 0.0051 0.0064 0.0316
Brugia malayi hypothetical protein 0.0024 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.0027 0.0018 0.009
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0071 0.0106 0.0384
Brugia malayi hypothetical protein 0.015 0.0261 0.128
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0035 0.0035
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.03 0.0558 0.0558
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0003 0.0059
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0012 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0013 0.027
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0017 0.0084
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0126 0.0213 0.0213
Brugia malayi Latrophilin receptor protein 2 0.0126 0.0213 0.1047
Schistosoma mansoni survival motor neuron protein 0.0148 0.0258 0.0971
Loa Loa (eye worm) hypothetical protein 0.015 0.0261 0.128
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0003 0.0059
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0017 0.0065
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0014
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0064 0.0242
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0752 0.1454 0.5464
Echinococcus multilocularis thyroid hormone receptor alpha 0.0051 0.0064 0.0064
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0003 0.0003
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0006 0.0023
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0016 0.0016
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.0064 0.0242
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0026 0.0015 0.0075
Schistosoma mansoni hypothetical protein 0.0081 0.0124 0.0468
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0027 0.0018 0.0067
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0012 0.0043
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0044 0.0218
Onchocerca volvulus 0.0148 0.0258 0.11
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0752 0.1454 0.5464
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0023 0.0113
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0003 0.0009
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0006 0.0019
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0003 0.0003
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.004 0.0044 0.0218
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0003 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0044 0.0179
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0003 0.0059
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0019 0.0003 0.001
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0006 0.0073
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.0064 0.0064
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0016 0.0079
Brugia malayi PHD-finger family protein 0.0032 0.0027 0.0134
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0019 0.0003 0.0059
Entamoeba histolytica acyl-coA synthetase, putative 0.0072 0.0107 0.173
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.008 0.2982
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0037 0.0037
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0018 0.0259
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0003 0.001
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0067 0.0329
Schistosoma mansoni hypothetical protein 0.0126 0.0213 0.0803
Schistosoma mansoni Smad4 0.0026 0.0016 0.0061
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0071 0.0106 0.0397
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0003 0.0059
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0019 0.0003 0.0009
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0006 0.0023
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0037 0.0135
Loa Loa (eye worm) beta-lactamase 0.0257 0.0473 0.2322
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0015 0.0075
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0126 0.0213 0.0213
Echinococcus granulosus prolyl endopeptidase 0.0027 0.0018 0.0069
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0003 0.0059
Loa Loa (eye worm) hypothetical protein 0.0051 0.0064 0.0316
Schistosoma mansoni hypothetical protein 0.0126 0.0213 0.0803
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0033 0.0033
Brugia malayi TAR-binding protein 0.0195 0.0352 0.1725
Schistosoma mansoni retinal dehydrogenase 0.0019 0.0003 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Echinococcus multilocularis acylamino acid releasing enzyme 0.0027 0.0018 0.0018
Plasmodium falciparum peptidase, putative 0.0027 0.0018 0.0606
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0027 0.0018 0.0069
Onchocerca volvulus 0.0105 0.0173 0.0732
Leishmania major dehydrogenase-like protein 0.0019 0.0003 0.0059
Brugia malayi hypothetical protein 0.0019 0.0003 0.0014
Onchocerca volvulus 0.0055 0.0074 0.0307
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0006 0.0132
Schistosoma mansoni ets-related 0.0246 0.0451 0.1695
Toxoplasma gondii serine carboxypeptidase s28 protein 0.004 0.0044 0.0937
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0175 0.031 0.1522
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0085
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0012 0.0043
Schistosoma mansoni carbonyl reductase 0.0019 0.0003 0.001
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0005 0.0022
Brugia malayi MH1 domain containing protein 0.0026 0.0016 0.0079
Loa Loa (eye worm) hypothetical protein 0.0051 0.0064 0.0316
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0064 0.0316
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.0064 0.0316
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.0064 0.0242
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0057
Trichomonas vaginalis D-aminoacylase, putative 0.0257 0.0473 0.2026
Brugia malayi prolyl oligopeptidase family protein 0.0116 0.0194 0.0951
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0003 0.001
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0003 0.001
Schistosoma mansoni hypothetical protein 0.0081 0.0124 0.0468
Schistosoma mansoni carbonyl reductase 0.0019 0.0003 0.001
Echinococcus multilocularis neuropeptide s receptor 0.0461 0.0878 0.0878
Mycobacterium leprae Probable oxidoreductase 0.0019 0.0003 0.001
Schistosoma mansoni alpha-glucosidase 0.0157 0.0275 0.1033
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0012 0.0012
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0006 0.0126
Schistosoma mansoni alpha-glucosidase 0.0157 0.0275 0.1033
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0044 0.0179
Schistosoma mansoni hypothetical protein 0.0126 0.0213 0.0803
Mycobacterium tuberculosis Probable lipase LipD 0.0257 0.0473 0.1472
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.0064 0.0316
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0017 0.0084
Plasmodium falciparum acyl-CoA synthetase 0.0054 0.0071 0.2641
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0017 0.0084
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0003 0.001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0065 0.0203
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0145 0.0251 0.0943
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0003 0.001
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0044 0.0179
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0167 0.0295 0.0295
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.0064 0.0316
Schistosoma mansoni alpha glucosidase 0.004 0.0044 0.0167
Loa Loa (eye worm) hypothetical protein 0.0054 0.0071 0.0348
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0081 0.0125 0.0611
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0037 0.0148
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0006 0.0031
Brugia malayi prolyl oligopeptidase family protein 0.0027 0.0018 0.009
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0081 0.0396
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.0064 0.0316
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.0084 0.013 0.0639
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0003 0.0059
Schistosoma mansoni hypothetical protein 0.0067 0.0097 0.0366
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0044 0.0179
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.008 0.1685
Trypanosoma brucei oligopeptidase b 0.0027 0.0018 0.0389
Echinococcus multilocularis oxidoreductase 0.0019 0.0003 0.0003
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0003 0.0059
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.034 0.0637 0.2395
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0013 0.0048
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0012 0.0057
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.034 0.0637 0.2395
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.0064 0.0316
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0016 0.0061
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0072 0.0107 0.0389
Loa Loa (eye worm) fli-1 protein 0.0246 0.0451 0.2212
Brugia malayi Calcitonin receptor-like protein seb-1 0.0397 0.0752 0.3687
Loa Loa (eye worm) hypothetical protein 0.0072 0.0107 0.0525
Loa Loa (eye worm) hypothetical protein 0.0103 0.0168 0.0823
Echinococcus multilocularis Smad4 0.0026 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0057
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0107 0.0525
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0003 0.0009
Toxoplasma gondii hypothetical protein 0.0027 0.0018 0.0389
Giardia lamblia Thymus-specific serine protease precursor 0.004 0.0044 0.3453
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0345 0.0647 0.2432
Echinococcus granulosus WW domain containing oxidoreductase 0.0019 0.0003 0.001
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0182 0.0325 0.1594
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0003 0.0059
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0072 0.0107 0.0389
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0006 0.0023
Echinococcus granulosus oxidoreductase 0.0019 0.0003 0.001
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0003 0.0059
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Schistosoma mansoni smad1 5 8 and 0.0026 0.0016 0.0061
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0257 0.0473 0.1472
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0003 0.0059
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0003 0.001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0107 0.0333
Loa Loa (eye worm) hypothetical protein 0.0054 0.0072 0.0354
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.008 0.03
Mycobacterium tuberculosis Probable dehydrogenase 0.0019 0.0003 0.0009
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0003 0.001
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0003 0.0009
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0397 0.0752 0.3687
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0012 0.0057
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0027 0.0018 0.0259
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0021 0.0078
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.008 0.1636
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0003 0.001
Brugia malayi hypothetical protein 0.0019 0.0003 0.0014
Plasmodium falciparum histone acetyltransferase GCN5 0.008 0.0123 0.466
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0027 0.0018 0.0069
Loa Loa (eye worm) dehydrogenase 0.0019 0.0003 0.0014
Echinococcus multilocularis geminin 0.0847 0.1643 0.1643
Loa Loa (eye worm) hypothetical protein 0.0257 0.0473 0.2322
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0116 0.0194 0.4095
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0018 0.0067
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0003 0.0059
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0027 0.0018 0.0259
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0003 0.0059
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0116 0.0194 0.4095
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0044 0.069
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0003 0.0059
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0008 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0107 0.0389
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0006 0.0019
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0051 0.0064 0.0316
Mycobacterium ulcerans oxidoreductase 0.0019 0.0003 0.001
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0012 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0195 0.0352 0.1322
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0054 0.0071 0.0221
Brugia malayi Serine carboxypeptidase S28 family protein 0.004 0.0044 0.0218
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.008 0.1685
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0057
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0003 0.0009
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0006 0.0023
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0035 0.0747
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0044 0.0937
Entamoeba histolytica hypothetical protein 0.0024 0.0013 0.0165
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.0064 0.0242
Echinococcus granulosus FTZ F1 alpha 0.0051 0.0064 0.0242
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0019 0.0003 0.001
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0003 0.0009
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0035 0.0133
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0019 0.0003 0.0059
Onchocerca volvulus 0.0021 0.0006 0.0015
Brugia malayi Fli-1 protein 0.0246 0.0451 0.2212
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0003 0.0003
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0257 0.0473 0.2322
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0006 0.0023
Echinococcus granulosus intermediate filament protein 0.0055 0.0074 0.0279
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0345 0.0647 0.2432
Echinococcus multilocularis neuropeptide receptor A26 0.0461 0.0878 0.0878
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0044 0.0044
Echinococcus multilocularis protein dispatched 1 0.0096 0.0154 0.0154
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.004 0.0044 0.0044
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0019 0.0003 0.0009
Brugia malayi hypothetical protein 0.0027 0.0017 0.0084
Brugia malayi Retinol dehydrogenase 12 0.0019 0.0003 0.0014
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.0064 0.0242
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0013 0.0013
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0071 0.0106 0.0328
Loa Loa (eye worm) hypothetical protein 0.0054 0.0071 0.0348
Brugia malayi nuclear hormone receptor 0.0051 0.0064 0.0316
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Giardia lamblia PHD finger protein 15 0.0028 0.0021 0.1487
Brugia malayi ecdysone receptor 0.0024 0.0012 0.0057
Brugia malayi jmjC domain containing protein 0.0036 0.0036 0.0178
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0019 0.0003 0.0009
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.009 0.0142 0.3003
Echinococcus multilocularis GPCR, family 2 0.0126 0.0213 0.0213
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0027 0.0018 0.0067
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0019 0.0003 0.001
Trichomonas vaginalis esterase, putative 0.0257 0.0473 0.2026
Onchocerca volvulus Alhambra homolog 0.0028 0.0021 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.0064 0.0316
Loa Loa (eye worm) hypothetical protein 0.0054 0.0071 0.0348
Loa Loa (eye worm) hypothetical protein 0.0069 0.0101 0.0497
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0107 0.0389
Loa Loa (eye worm) hypothetical protein 0.0257 0.0473 0.2322
Echinococcus granulosus geminin 0.0847 0.1643 0.6176
Loa Loa (eye worm) prolyl oligopeptidase 0.0345 0.0647 0.3173
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0012 0.0038
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1047 0.2039 1
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0013 0.027
Brugia malayi nuclear receptor NHR-88 0.0024 0.0012 0.0057
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0019 0.0003 0.0009
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.009 0.0142 0.3003
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.0064 0.0316
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.015 0.0262 0.0984
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0095 0.0095
Brugia malayi tailless protein 0.0024 0.0012 0.0057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0065 0.0203
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0107 0.0389
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.0064 0.0316
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.034 0.0637 0.2395
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.0064 0.0265
Echinococcus multilocularis Niemann Pick C1 protein 0.0279 0.0517 0.0517
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0027 0.0018 0.0389
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0013 0.0048
Onchocerca volvulus 0.0257 0.0473 0.2026
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0071 0.0106 0.0106
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0006 0.0023
Echinococcus multilocularis sterol regulatory element binding protein 0.0084 0.013 0.013
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0067 0.0097 0.0366
Schistosoma mansoni coup transcription factor 0.0051 0.0064 0.0242
Loa Loa (eye worm) hypothetical protein 0.0257 0.0473 0.2322
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0397 0.0752 0.3687
Giardia lamblia Serine peptidase, putative 0.004 0.0044 0.3453
Echinococcus multilocularis microtubule associated protein 2 0.1361 0.266 0.266
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0003 0.0059
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0019 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.0473 1
Toxoplasma gondii ABC1 family protein 0.0257 0.0473 1
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0003 0.0059
Brugia malayi nuclear receptor RXR 0.0027 0.0017 0.0084
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0019 0.0003 0.0009
Toxoplasma gondii exonuclease III APE 0.0058 0.008 0.1685
Echinococcus multilocularis lysosomal alpha glucosidase 0.0182 0.0325 0.0325
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0014
Loa Loa (eye worm) hypothetical protein 0.0156 0.0274 0.1346
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0044 0.0179
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.015 0.0262 0.0984
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0035 0.0133
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0149 0.056
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0003 0.0009
Echinococcus granulosus microtubule associated protein 2 0.1361 0.266 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0012 0.0012
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.008 0.0331
Schistosoma mansoni smad 0.0026 0.0016 0.0061
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0003 0.0059
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0003 0.0059
Brugia malayi hypothetical protein 0.0097 0.0156 0.0764
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0019 0.0003 0.001
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0008 0.0031
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Schistosoma mansoni hypothetical protein 0.002 0.0005 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0019 0.0003 0.0014
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0072 0.0107 0.0389
Giardia lamblia Histone acetyltransferase GCN5 0.008 0.0123 1
Echinococcus granulosus survival motor neuron protein 1 0.0727 0.1405 0.5283
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.0064 0.0242
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0006 0.0019
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0064 0.0242
Echinococcus multilocularis Niemann Pick C1 protein 0.0195 0.0351 0.0351
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0006 0.0019
Trypanosoma brucei prolyl endopeptidase 0.0027 0.0018 0.0389
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Schistosoma mansoni hypothetical protein 0.0148 0.0258 0.0971
Loa Loa (eye worm) hypothetical protein 0.0272 0.0503 0.2465
Leishmania major hypothetical protein, conserved 0.0019 0.0003 0.0059
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0345 0.0647 0.0647
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0019 0.0003 0.001
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0021 0.0101
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0035 0.0747
Loa Loa (eye worm) oxidoreductase 0.0019 0.0003 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0167 0.0295 0.1109
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0035 0.0747
Trypanosoma brucei PAB1-binding protein , putative 0.015 0.0261 0.5513
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0035 0.2708
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0012 0.0057
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0064 0.0316
Trypanosoma cruzi oligopeptidase b 0.0027 0.0018 0.0389
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.004 0.0044 0.0689
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0019 0.0003 0.0003
Echinococcus multilocularis retinol dehydrogenase 13 0.0019 0.0003 0.0003
Mycobacterium ulcerans dehydrogenase/reductase 0.0019 0.0003 0.001
Brugia malayi Dehydrogenases, short chain protein 30 0.0019 0.0003 0.0014
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0006 0.0133
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0019 0.0003 0.0059
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0003 0.0009
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0035 0.0133
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0006 0.0031
Schistosoma mansoni zinc finger protein 0.0024 0.0012 0.0043
Loa Loa (eye worm) TAR-binding protein 0.0195 0.0352 0.1725
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0037 0.0148
Brugia malayi Serine protease Z688.6 precursor 0.004 0.0044 0.0218
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.0064 0.0242
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0044 0.0179
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0035 0.0133
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0107 0.2262
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Mycobacterium ulcerans transcriptional regulator 0.1406 0.275 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0014
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0198 0.0357 0.1343
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0027 0.0018 0.0057
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.008 0.5
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0012 0.0043
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0034 0.0129
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0257 0.0473 0.2322
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0027 0.0018 0.0067
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0107 0.0525
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0012 0.0038
Echinococcus multilocularis conserved hypothetical protein 0.0019 0.0003 0.0003
Trypanosoma cruzi PAB1-binding protein , putative 0.015 0.0261 0.5513
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0257 0.0473 0.1472
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0006 0.0019
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0148 0.0258 0.1267
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0003 0.001
Echinococcus granulosus Protein patched homolog 1 0.0084 0.013 0.049
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0064 0.0316
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0126 0.0213 0.0803
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0006 0.0132
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.004 0.0044 0.0937
Brugia malayi hypothetical protein 0.0024 0.0012 0.0057
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.008 0.1685
Mycobacterium tuberculosis Probable hydrolase 0.0257 0.0473 0.1472
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0019 0.0003 0.0059
Brugia malayi Cytochrome P450 family protein 0.0076 0.0116 0.0567
Schistosoma mansoni hypothetical protein 0.0272 0.0503 0.1889
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0064 0.0316
Loa Loa (eye worm) hypothetical protein 0.0054 0.0071 0.0348
Loa Loa (eye worm) hypothetical protein 0.0072 0.0107 0.0525
Brugia malayi hypothetical protein 0.0727 0.1405 0.6893
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0003 0.0059
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Brugia malayi latrophilin 2 splice variant baaae 0.0272 0.0503 0.2465
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0043 0.0043
Echinococcus multilocularis lamin dm0 0.0055 0.0074 0.0074
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0019 0.0003 0.0009
Entamoeba histolytica prolyl oligopeptidase family protein 0.0027 0.0018 0.0259
Trichomonas vaginalis bromodomain-containing protein, putative 0.009 0.0142 0.06
Leishmania major pteridine reductase 1 0.0019 0.0003 0.0059
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0044 0.0179
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0116 0.0194 0.0729
Loa Loa (eye worm) hypothetical protein 0.0167 0.0295 0.1448
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0064 0.0242
Echinococcus granulosus neuropeptide receptor A26 0.0461 0.0878 0.3301
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0107 0.2262
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0003 0.0003
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.0064 0.0242
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0006 0.0132
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0031
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0006 0.0132
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.004 0.0044 0.0937
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0057
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0059
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0071 0.0106 0.2231
Echinococcus multilocularis prolyl endopeptidase 0.0027 0.0018 0.0018
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0071 0.0106 0.0397
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0037 0.014
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0084
Echinococcus granulosus lysosomal alpha glucosidase 0.0182 0.0325 0.1222
Onchocerca volvulus Prolyl endopeptidase homolog 0.0027 0.0018 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0035 0.014
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0008 0.0031
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0006 0.0023
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0034 0.0034
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0037 0.4473
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0035 0.0747
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0012 0.0043
Giardia lamblia Alanyl dipeptidyl peptidase 0.0027 0.0018 0.13
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0019 0.0003 0.0003
Toxoplasma gondii carbonyl reductase 1, putative 0.0019 0.0003 0.0059
Schistosoma mansoni ap endonuclease 0.0058 0.008 0.03
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0006 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0003 0.0059
Brugia malayi hypothetical protein 0.0027 0.0017 0.0084
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0037 0.0786
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.0064 0.0316
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.0064 0.0242
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0003 0.0009
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0095 0.0358
Loa Loa (eye worm) hypothetical protein 0.0257 0.0473 0.2322
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0044 0.069
Brugia malayi Pre-SET motif family protein 0.015 0.0262 0.1284
Loa Loa (eye worm) hypothetical protein 0.0727 0.1405 0.6893
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0013 0.027
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0044 0.0937
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0074 0.0364
Loa Loa (eye worm) hypothetical protein 0.0047 0.0058 0.0285
Entamoeba histolytica prolyl oligopeptidase family protein 0.0027 0.0018 0.0259
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0006 0.0132
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0019 0.0003 0.001
Brugia malayi RNA binding protein 0.0195 0.0352 0.1725
Loa Loa (eye worm) oxidoreductase 0.0019 0.0003 0.0014
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0044 0.0179
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0003 0.0059
Plasmodium vivax histone acetyltransferase GCN5, putative 0.009 0.0142 0.2962
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0064 0.0242
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0044 0.0179
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.0064 0.0064
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0044 0.0179
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0006 0.0023
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0044 0.0179
Mycobacterium ulcerans short-chain type oxidoreductase 0.0019 0.0003 0.001
Entamoeba histolytica prolyl oligopeptidase family protein 0.0027 0.0018 0.0259
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0049 0.0062 0.0304
Onchocerca volvulus 0.1192 0.2326 1
Entamoeba histolytica hypothetical protein 0.0324 0.0606 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.008 1
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0003 0.001
Brugia malayi hypothetical protein 0.0089 0.014 0.0685
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.034 0.0637 0.3125
Onchocerca volvulus 0.0072 0.0107 0.0449
Leishmania major hypothetical protein, conserved 0.0019 0.0003 0.0059
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Schistosoma mansoni hypothetical protein 0.0324 0.0606 0.2276
Brugia malayi hypothetical protein 0.0455 0.0867 0.425
Mycobacterium ulcerans TetR family transcriptional regulator 0.1406 0.275 1
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0116 0.0194 0.4095
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0019 0.0003 0.0009
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0044 0.0179
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0035 0.0035
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Brugia malayi Bromodomain containing protein 0.0045 0.0053 0.0262
Loa Loa (eye worm) hypothetical protein 0.0051 0.0064 0.0316
Giardia lamblia Alanyl dipeptidyl peptidase 0.0027 0.0018 0.13
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.008 0.008
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0006 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.0064 0.0316
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0149 0.0149
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Echinococcus granulosus peregrin 0.0038 0.004 0.0149
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0018 0.0389
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0324 0.0606 0.2276
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0019 0.0003 0.0059
Schistosoma mansoni cellular tumor antigen P53 0.0156 0.0274 0.1031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0057
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0126 0.0213 0.1047
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.034 0.0637 0.2395
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0006 0.0015
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0064 0.0242
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0019 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0018 0.009
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0057
Trichomonas vaginalis D-aminoacylase, putative 0.0257 0.0473 0.2026
Brugia malayi Bromodomain containing protein 0.0038 0.004 0.0195
Schistosoma mansoni ap endonuclease 0.0058 0.008 0.03
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0003 0.0009
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0006 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0003 0.0059
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.003 0.0092
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0021 0.038
Brugia malayi CHE-14 protein 0.0084 0.013 0.0639
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0021 0.0437
Schistosoma mansoni lamin 0.0055 0.0074 0.0279
Schistosoma mansoni microtubule-associated protein tau 0.1361 0.266 1
Loa Loa (eye worm) oxidoreductase 0.0019 0.0003 0.0014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0084
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.007 0.0102 0.0501
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0037 0.0786
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0003 0.0009
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0003 0.001
Loa Loa (eye worm) oxidoreductase 0.0019 0.0003 0.0014
Echinococcus granulosus lamin 0.0055 0.0074 0.0279
Brugia malayi conserved hypotetical protein 0.0024 0.0012 0.0057
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0003 0.001
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.0064 0.0242
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0037 0.0571
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.004 0.0044 0.0179
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0019 0.0003 0.0059
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0023 0.0113
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.004 0.0044 0.0167
Loa Loa (eye worm) hypothetical protein 0.0126 0.0213 0.1047
Brugia malayi Inositol-1 0.0037 0.0037 0.0183
Trichomonas vaginalis penicillin-binding protein, putative 0.0257 0.0473 0.2026
Plasmodium vivax SET domain protein, putative 0.015 0.0262 0.5505
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0006 0.0023
Echinococcus granulosus steroid dehydrogenase 0.0019 0.0003 0.001
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0051 0.0064 0.0316
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.004 0.0044 0.0179
Loa Loa (eye worm) acetyltransferase 0.03 0.0558 0.2737
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0195 0.0352 0.1725
Plasmodium vivax hypothetical protein, conserved 0.0257 0.0473 1
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0006 0.0132
Echinococcus granulosus Dipeptidyl peptidase 9 0.0116 0.0194 0.0729
Onchocerca volvulus 0.0055 0.0074 0.0307
Echinococcus multilocularis protein patched 0.0084 0.013 0.013
Schistosoma mansoni hypothetical protein 0.0081 0.0124 0.0468
Mycobacterium ulcerans oxidoreductase 0.0019 0.0003 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.015 0.0261 0.5513
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0019 0.0003 0.0059
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0044 0.0179
Brugia malayi steroid hormone receptor 0.0051 0.0064 0.0316
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0003 0.001
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0036 0.0136
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.015 0.0262 0.5532
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0003 0.0009
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0084 0.013 0.0639
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0019 0.0003 0.0014
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0044 0.0179
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0006 0.0031
Echinococcus granulosus zinc finger protein 0.0027 0.0017 0.0064
Plasmodium vivax acyl-CoA synthetase, putative 0.0054 0.0071 0.1449
Brugia malayi beta-lactamase 0.0257 0.0473 0.2322
Loa Loa (eye worm) transcription factor SMAD2 0.0384 0.0725 0.3553
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0006 0.0019
Brugia malayi nuclear receptor RXR 0.0024 0.0012 0.0057
Leishmania major short chain dehydrogenase, putative 0.0019 0.0003 0.0059
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0044 0.0167
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0019 0.0003 0.001
Schistosoma mansoni tar DNA-binding protein 0.0195 0.0352 0.1322
Loa Loa (eye worm) dehydrogenase 0.0019 0.0003 0.0014
Schistosoma mansoni inositol monophosphatase 0.0037 0.0037 0.014
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0044 0.0218
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.008 0.029
Brugia malayi MH2 domain containing protein 0.0026 0.0016 0.0079
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0257 0.0473 0.2322
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.0006 0.0023
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0107 0.2262
Brugia malayi Niemann-Pick C1 protein precursor 0.0195 0.0351 0.1723
Onchocerca volvulus 0.004 0.0044 0.0179
Schistosoma mansoni tar DNA-binding protein 0.0195 0.0352 0.1322
Loa Loa (eye worm) cytochrome P450 family protein 0.0076 0.0116 0.0567
Brugia malayi Bromodomain containing protein 0.0081 0.0125 0.0613
Echinococcus granulosus histone lysine methyltransferase setb 0.0167 0.0295 0.1109
Brugia malayi jmjC domain containing protein 0.0093 0.0149 0.073
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0017 0.0065
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0345 0.0647 0.2774
Brugia malayi oxidoreductase 0.0019 0.0003 0.0014
Onchocerca volvulus 0.0257 0.0473 0.2026
Loa Loa (eye worm) hypothetical protein 0.0051 0.0064 0.0316
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0006 0.0019
Echinococcus granulosus beta LACTamase domain containing family member 0.0257 0.0473 0.178
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0126 0.0213 0.0803
Loa Loa (eye worm) hypothetical protein 0.0049 0.0061 0.0299
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0012 0.0043
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0012 0.0057
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0064 0.0064
Schistosoma mansoni bromodomain containing protein 0.007 0.0102 0.0384
Schistosoma mansoni hypothetical protein 0.0028 0.0021 0.0078
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0027 0.0018 0.0069
Plasmodium falciparum ataxin-2 like protein, putative 0.015 0.0261 1
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0003 0.001
Echinococcus granulosus neuropeptide s receptor 0.0461 0.0878 0.3301
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0019 0.0003 0.0009
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0006 0.0023
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0003 0.0009
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0012 0.0057
Schistosoma mansoni smad1 5 8 and 0.0026 0.0016 0.0061
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0006 0.0019
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.008 0.0391
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.0064 0.0265
Echinococcus multilocularis zinc finger protein 0.0027 0.0017 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Onchocerca volvulus 0.0051 0.0064 0.0265
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0074 0.0364
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.008 0.0391
Toxoplasma gondii prolyl endopeptidase 0.0027 0.0018 0.0389
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0016 0.0061
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.0064 0.0265
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0057
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0107 0.0389
Plasmodium vivax ataxin-2 like protein, putative 0.015 0.0261 0.5486
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0054 0.0071 0.5
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0027 0.0018 0.0389
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0003 0.001
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0107 0.0525
Schistosoma mansoni hypothetical protein 0.0081 0.0124 0.0468
Trypanosoma brucei glucosidase, putative 0.004 0.0044 0.0937
Loa Loa (eye worm) latrophilin receptor protein 2 0.0126 0.0213 0.1047
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0006 0.0132
Echinococcus granulosus lamin dm0 0.0055 0.0074 0.0279
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0044 0.0179
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0027 0.0018 0.0069
Onchocerca volvulus 0.0041 0.0045 0.018
Leishmania major oxidoreductase-like protein 0.0019 0.0003 0.0059
Trypanosoma brucei oxidoreductase-like protein 0.0019 0.0003 0.0059
Leishmania major hypothetical protein, conserved 0.0019 0.0003 0.0059
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0003 0.001
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0012 0.0043
Brugia malayi Steroid receptor seven-up type 2 0.0051 0.0064 0.0316
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0019 0.0003 0.001
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0003 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0064 0.0242
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0067 0.0097 0.0097
Leishmania major hypothetical protein, conserved 0.0257 0.0473 1
Echinococcus granulosus hypothetical protein 0.0019 0.0003 0.001
Echinococcus granulosus GA binding protein alpha chain 0.0081 0.0125 0.0469
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0044 0.0179
Schistosoma mansoni intermediate filament proteins 0.0055 0.0074 0.0279
Mycobacterium tuberculosis Probable lipase LipE 0.0257 0.0473 0.1472
Onchocerca volvulus 0.0455 0.0867 0.3719
Onchocerca volvulus 0.0257 0.0473 0.2026
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0006 0.0023
Loa Loa (eye worm) oxidoreductase 0.0019 0.0003 0.0014
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0044 0.0179
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0006 0.0006
Echinococcus multilocularis beta LACTamase domain containing family member 0.0257 0.0473 0.0473
Loa Loa (eye worm) oxidoreductase 0.0019 0.0003 0.0014
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.009 0.0142 0.06
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0027 0.0018 0.0389
Trichomonas vaginalis penicillin-binding protein, putative 0.0257 0.0473 0.2026
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0003 0.0059
Brugia malayi MH2 domain containing protein 0.0026 0.0016 0.0079
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0019 0.0003 0.001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0064 0.0316
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.03 0.0558 0.2098
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0059
Echinococcus granulosus expressed conserved protein 0.0183 0.0328 0.1232
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0044 0.0937
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0003 0.0059
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0035 0.0035
Loa Loa (eye worm) RNA binding protein 0.0195 0.0352 0.1725
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.008 0.6398
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.034 0.0637 0.3125
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0006 0.0023
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0107 0.173
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.0064 0.0316
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0003 0.001
Loa Loa (eye worm) bromodomain containing protein 0.0025 0.0013 0.0065
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0044 0.0179
Schistosoma mansoni gabp alpha 0.0081 0.0125 0.0469
Leishmania major 3-keto-dihydrosphingosine reductase 0.0019 0.0003 0.0059
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0057
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0006 0.0057
Echinococcus multilocularis survival motor neuron protein 1 0.0727 0.1405 0.1405
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.004 0.0044 0.0689
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0324 0.0606 0.0606
Echinococcus granulosus jumonji domain containing protein 0.004 0.0043 0.0161
Leishmania major oligopeptidase b 0.0027 0.0018 0.0389
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0003 0.0003
Echinococcus granulosus Niemann Pick C1 protein 0.0195 0.0351 0.1321
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0057
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Entamoeba histolytica acetyltransferase, GNAT family 0.008 0.0123 0.1996
Trichomonas vaginalis conserved hypothetical protein 0.017 0.0301 0.1283
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0029
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0037 0.0786
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0006 0.0132
Loa Loa (eye worm) hypothetical protein 0.0175 0.031 0.1522
Plasmodium falciparum ataxin-2 like protein, putative 0.015 0.0261 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.0064 0.0242
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0016 0.0061
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.0071 0.0258
Brugia malayi nuclear hormone receptor 0.0024 0.0012 0.0057
Loa Loa (eye worm) oxidoreductase 0.0019 0.0003 0.0014
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0036 0.0136
Trypanosoma cruzi prolyl endopeptidase 0.0027 0.0018 0.0389
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0195 0.0351 0.5782
Leishmania major hypothetical protein, conserved 0.0019 0.0003 0.0059
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.004 0.0044 0.0179
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0003 0.001
Trypanosoma brucei prolyl oligopeptidase, putative 0.0027 0.0018 0.0389
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0019 0.0003 0.001
Echinococcus multilocularis lysosomal alpha glucosidase 0.0182 0.0325 0.0325
Schistosoma mansoni smad1 5 8 and 0.0026 0.0016 0.0061
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0003 0.0059
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.003 0.0108
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0017 0.0065
Trichomonas vaginalis set domain proteins, putative 0.1192 0.2326 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.0064 0.0316
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0019 0.0003 0.0059
Echinococcus granulosus histone acetyltransferase KAT2B 0.009 0.0142 0.0534
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0064 0.0316
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.0064 0.0242
Schistosoma mansoni carbonyl reductase 0.0019 0.0003 0.001
Brugia malayi prolyl oligopeptidase family protein 0.0027 0.0018 0.009
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0017 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.0064 0.0316
Entamoeba histolytica hypothetical protein 0.0324 0.0606 1
Echinococcus granulosus acylamino acid releasing enzyme 0.0027 0.0018 0.0069
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0059
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0017 0.0065
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Mycobacterium leprae conserved hypothetical protein 0.0257 0.0473 0.1722
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0257 0.0473 0.2322
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0027 0.0018 0.0389
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0065 0.0203
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0084
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.0064 0.0242
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0051 0.0064 0.0242
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0072 0.0107 0.0389
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0006 0.0023
Brugia malayi nuclear receptor NHR-67 0.0024 0.0012 0.0057
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0021 0.0437
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0035 0.014
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0019 0.0003 0.0059
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0021 0.0021
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0019 0.0003 0.001
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0006 0.0019
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0006 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0003 0.0059
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0071 0.0106 0.0384
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0014
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0035 0.0133
Loa Loa (eye worm) hypothetical protein 0.0036 0.0035 0.0174
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0003 0.0059
Leishmania major short chain dehydrogenase-like protein 0.0019 0.0003 0.0059
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0003 0.001
Mycobacterium tuberculosis Probable esterase LipL 0.0257 0.0473 0.1472
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0019 0.0003 0.001
Brugia malayi dehydrogenases, short chain protein 9 0.0019 0.0003 0.0014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0014
Onchocerca volvulus 0.0024 0.0012 0.0038
Schistosoma mansoni lamin 0.0055 0.0074 0.0279
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0027 0.0018 0.0067
Loa Loa (eye worm) hypothetical protein 0.004 0.0044 0.0218
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0003 0.001
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0019 0.0003 0.0009
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0072 0.0107 0.0333
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.004 0.0044 0.0689
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0035 0.0174
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0006 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0014
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.0064 0.0064
Loa Loa (eye worm) oxidoreductase 0.0019 0.0003 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0006 0.0023
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0003 0.0003
Brugia malayi Pre-SET motif family protein 0.1047 0.2039 1
Schistosoma mansoni patched 1 0.0084 0.013 0.049
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0035 0.014
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0059
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0111 0.0417
Mycobacterium leprae Probable transcriptional regulatory repressor protein (TetR-family) EthR 0.1406 0.275 1
Echinococcus granulosus smad 0.0026 0.0016 0.0061
Loa Loa (eye worm) hypothetical protein 0.004 0.0044 0.0218
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0084
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0003 0.001
Onchocerca volvulus 0.015 0.0262 0.1115
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0037 0.0786
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0116 0.0194 0.0194
Brugia malayi MH2 domain containing protein 0.0384 0.0725 0.3553
Schistosoma mansoni tar DNA-binding protein 0.0195 0.0352 0.1322
Echinococcus multilocularis musashi 0.0055 0.0074 0.0074
Mycobacterium ulcerans carveol-like dehydrogenase 0.0019 0.0003 0.001
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0003 0.0059
Schistosoma mansoni hypothetical protein 0.0847 0.1643 0.6176
Loa Loa (eye worm) oxidoreductase 0.0019 0.0003 0.0014
Loa Loa (eye worm) Smad1 0.0026 0.0016 0.0079
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0257 0.0473 0.1472
Leishmania major hypothetical protein, conserved 0.015 0.0261 0.5513
Loa Loa (eye worm) MH2 domain-containing protein 0.0384 0.0725 0.3553
Echinococcus granulosus Niemann Pick C1 protein 0.0279 0.0517 0.1945
Echinococcus multilocularis GA binding protein alpha chain 0.0081 0.0125 0.0125
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0006 0.0023
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0116 0.0194 0.4095
Entamoeba histolytica hypothetical protein 0.0324 0.0606 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0006 0.0023
Brugia malayi Ets-domain containing protein 0.0081 0.0125 0.0611
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0003 0.0059
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.0064 0.0316
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0059
Mycobacterium ulcerans lipase LipD 0.0257 0.0473 0.1722
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0006 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0014
Plasmodium falciparum phd finger protein, putative 0.0028 0.0021 0.0693
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0107 0.173
Onchocerca volvulus 0.0021 0.0006 0.0015
Brugia malayi MH1 domain containing protein 0.0026 0.0016 0.0079
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0464 0.0883 0.4331
Loa Loa (eye worm) inositol-1 0.0037 0.0037 0.0183
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0 0.0001
Brugia malayi RNA recognition motif domain containing protein 0.0195 0.0352 0.1725
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0012 0.0043
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0044 0.0179
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0003 0.001
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0027 0.0018 0.0389
Brugia malayi Ets-domain containing protein 0.0081 0.0125 0.0611
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0107 0.0389
Schistosoma mansoni hypothetical protein 0.0126 0.0213 0.0803
Loa Loa (eye worm) hypothetical protein 0.0038 0.0039 0.0192
Mycobacterium ulcerans esterase/lipase LipP 0.0257 0.0473 0.1722
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.004 0.0044 0.0218
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0027 0.0018 0.0389
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0014
Loa Loa (eye worm) hypothetical protein 0.0089 0.014 0.0685
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.008 0.1277
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0003 0.001
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1642 0.3217 1
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0006 0.0031
Loa Loa (eye worm) hypothetical protein 0.0051 0.0064 0.0316
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0012 0.0057
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.0064 0.0064
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0006 0.0023
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0044 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.0064 0.0316
Loa Loa (eye worm) hypothetical protein 0.0027 0.0018 0.009
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.008 0.0331
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0003 0.0059
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.0064 0.0242
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0064 0.0064
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0003 0.0059
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0036 0.0178
Onchocerca volvulus 0.0156 0.0274 0.1169
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0003 0.0003
Brugia malayi Dehydrogenases, short chain protein 2 0.0019 0.0003 0.0014
Loa Loa (eye worm) hypothetical protein 0.0195 0.0351 0.1723
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.034 0.0637 0.0637
Leishmania major hypothetical protein, conserved 0.0019 0.0003 0.0059
Entamoeba histolytica hypothetical protein 0.0324 0.0606 1
Brugia malayi PHD-finger family protein 0.0028 0.0021 0.0101
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0019 0.0003 0.001
Echinococcus multilocularis tumor protein p63 0.1069 0.2082 0.2082
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0003 0.0014
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0016 0.0079
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0003 0.001
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0019 0.0003 0.0009
Schistosoma mansoni zinc finger protein 0.0027 0.0017 0.0064
Leishmania major short chain dehydrogenase, putative 0.0019 0.0003 0.0059
Echinococcus multilocularis smad 0.0026 0.0016 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.0064 0.0316
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0006 0.0132
Echinococcus granulosus sterol regulatory element binding protein 0.0084 0.013 0.049
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0013 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0044 0.0937
Mycobacterium tuberculosis Conserved protein 0.0257 0.0473 0.1472
Onchocerca volvulus 0.0021 0.0006 0.0015
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0057
Brugia malayi intermediate filament protein 0.0055 0.0074 0.0364
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0257 0.0473 0.1722
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0018 0.0332
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0006 0.0132
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.008 0.0248
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0003 0.001
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.015 0.0262 0.0262
Loa Loa (eye worm) hypothetical protein 0.0028 0.0021 0.0101
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0167 0.0295 0.1109
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0003 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.013 0.0549
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0003 0.0009
Echinococcus granulosus Smad4 0.0026 0.0016 0.0061
Mycobacterium ulcerans dehydrogenase 0.0019 0.0003 0.001
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0074 0.0364
Mycobacterium tuberculosis Conserved protein 0.0257 0.0473 0.1472
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0006 0.0132
Trypanosoma brucei hypothetical protein, conserved 0.0257 0.0473 1
Brugia malayi prolyl oligopeptidase family protein 0.0345 0.0647 0.3173
Toxoplasma gondii LsmAD domain-containing protein 0.015 0.0261 0.5513
Echinococcus multilocularis expressed conserved protein 0.0183 0.0328 0.0328
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.0473 1
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0006 0.0023
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0003 0.0059
Echinococcus granulosus tumor protein p63 0.1069 0.2082 0.7828
Mycobacterium tuberculosis Conserved protein 0.0257 0.0473 0.1472
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.008 0.1685
Echinococcus granulosus GPCR family 2 0.0126 0.0213 0.0803
Echinococcus multilocularis tar DNA binding protein 0.0195 0.0352 0.0352
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0012 0.0012
Brugia malayi beta-lactamase family protein 0.0257 0.0473 0.2322
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.0064 0.0064
Echinococcus granulosus hypothetical protein 0.0019 0.0003 0.001
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0003 0.001
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Trypanosoma cruzi oligopeptidase b 0.0027 0.0018 0.0389
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.034 0.0637 0.2395
Loa Loa (eye worm) oxidoreductase 0.0021 0.0006 0.0031
Brugia malayi Smad1 0.0026 0.0016 0.0079
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0027 0.0018 0.0389
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0044 0.0179
Brugia malayi follicle stimulating hormone receptor 0.0464 0.0883 0.4331
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0003 0.0059
Echinococcus granulosus histone acetyltransferase KAT2B 0.0289 0.0537 0.2018
Loa Loa (eye worm) DR-78 0.0024 0.0012 0.0057
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0003 0.0059
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0003 0.0059
Loa Loa (eye worm) hypothetical protein 0.0051 0.0064 0.0316
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0016 0.0016
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0019 0.0003 0.0014
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0006 0.0015
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0116 0.0194 0.4095
Schistosoma mansoni hypothetical protein 0.0847 0.1643 0.6176
Brugia malayi nuclear receptor NHR-88 0.0051 0.0064 0.0316
Loa Loa (eye worm) hypothetical protein 0.0054 0.0071 0.0348
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0036 0.0136
Brugia malayi Serine protease Z688.6 precursor 0.004 0.0044 0.0218
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0003 0.001
Schistosoma mansoni transcription factor LCR-F1 0.0324 0.0606 0.2276
Trichomonas vaginalis D-aminoacylase, putative 0.0257 0.0473 0.2026
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0003 0.001
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0752 0.1454 0.1454
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0071 0.0106 0.0518
Brugia malayi acetyltransferase, GNAT family protein 0.03 0.0558 0.2737
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0013 0.0063
Brugia malayi prolyl oligopeptidase family protein 0.0027 0.0018 0.009
Onchocerca volvulus 0.0024 0.0012 0.0038
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0037 0.0786
Loa Loa (eye worm) hypothetical protein 0.0455 0.0867 0.425
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0012 0.0057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0065 0.0203
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0003 0.0059
Mycobacterium ulcerans hypothetical protein 0.0257 0.0473 0.1722
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0064 0.0316
Brugia malayi hypothetical protein 0.0324 0.0606 0.297
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0017 0.0017
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0012 0.0057
Mycobacterium tuberculosis Transcriptional regulatory repressor protein (TetR-family) EthR 0.1406 0.275 0.8547
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0018 0.0389
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0003 0.0059
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0019 0.0003 0.0003
Mycobacterium ulcerans AcrR family transcriptional regulator 0.1406 0.275 1
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.004 0.0044 0.0167

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Antagonist activity at human CXCR5 expressed in mouse L1.2 cells assessed as inhibition of CXCL13-induced chemotaxis up to 10 uM after 4 hrs ChEMBL. 20483605
IC50 (functional) = 885 nM Antagonist activity at human CXCR3 expressed in mouse L1.2 cells assessed as inhibition of IP10-induced chemotaxis after 4 hrs ChEMBL. 20483605

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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