Detailed information for compound 168355

Basic information

Technical information
  • TDR Targets ID: 168355
  • Name: 2-(4-hydroxy-3-methoxyphenyl)ethylazanium
  • MW: 168.213 | Formula: C9H14NO2+
  • H donors: 2 H acceptors: 1 LogP: 0.86 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(ccc1O)CC[NH3+]
  • InChi: 1S/C9H13NO2/c1-12-9-6-7(4-5-10)2-3-8(9)11/h2-3,6,11H,4-5,10H2,1H3/p+1
  • InChiKey: DIVQKHQLANKJQO-UHFFFAOYSA-O  


Substructure search Similarity search

Network

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Synonyms

  • 2-(4-hydroxy-3-methoxy-phenyl)ethylammonium
  • 2-(4-hydroxy-3-methoxyphenyl)ethylammonium
  • 2-(4-hydroxy-3-methoxy-phenyl)ethylazanium
  • homovanillylammonium
  • 3-methoxytyramine
  • ZINC00119675

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0263 0.0751 0.8711
Loa Loa (eye worm) hypothetical protein 0.0034 0.0051 0.005
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0095 0.0238 0.1806
Echinococcus granulosus zinc finger protein 0.2784 0.8475 0.9133
Loa Loa (eye worm) steroid hormone receptor 0.0083 0.02 0.0211
Schistosoma mansoni hypothetical protein 0.0102 0.026 0.0281
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0043 0.0078 0.0135
Schistosoma mansoni nuclear receptor nhr-48 0.0039 0.0066 0.0072
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0083 0.02 0.0216
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0145 0.039 0.0421
Mycobacterium ulcerans hypothetical protein 0.0165 0.0454 0.3441
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Echinococcus multilocularis Aminotransferase class III 0.0022 0.0013 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0043 0.0078 0.0135
Echinococcus multilocularis heat shock protein 90 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0083 0.02 0.0211
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0153 0.0415 0.0443
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0059 0.0196
Leishmania major importin beta-1 subunit, putative 0.0025 0.0023 0.0171
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0025 0.0023 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0059 0.0646
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.02 0.0216
Brugia malayi Cytochrome P450 family protein 0.0062 0.0138 0.0149
Schistosoma mansoni aldehyde dehydrogenase 0.0448 0.1319 0.1421
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0034 0.0051 0.0055
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0025 0.0023 0.0025
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0043 0.0078 0.0593
Plasmodium vivax importin-beta 2, putative 0.003 0.004 0.0464
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0043 0.0078 0.0135
Treponema pallidum gamma-glutamyl phosphate reductase 0.0025 0.0023 0.0303
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0111 0.0287 0.2179
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0095 0.0238 0.1806
Onchocerca volvulus 0.0043 0.0078 0.0233
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0263 0.0751 0.0805
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0059 0.0196
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0095 0.0238 0.2761
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0263 0.0751 0.8631
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0263 0.0751 0.0751
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0043 0.0078 0.0135
Trypanosoma brucei heat shock protein 90, putative 0.0026 0.0027 0.0294
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0111 0.0287 0.3162
Mycobacterium ulcerans hypothetical protein 0.0299 0.0863 0.654
Brugia malayi hypothetical protein 0.0039 0.0066 0.0072
Brugia malayi MBOAT family protein 0.0263 0.0751 0.081
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0317 0.0919 0.0919
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0083 0.02 0.0216
Leishmania major glycerol uptake protein, putative 0.0263 0.0751 0.5697
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Schistosoma mansoni lipoxygenase 0.0192 0.0534 0.0576
Echinococcus multilocularis zinc finger protein 0.2784 0.8475 0.8475
Trypanosoma brucei unspecified product 0.002 0.0009 0.0103
Schistosoma mansoni cpg binding protein 0.0126 0.0333 0.0359
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0025 0.0023 0.0173
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.02 0.0216
Schistosoma mansoni rab6-interacting 0.0043 0.0078 0.0085
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.002 0.0009 0.001
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.002 0.0009 0.001
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0037 0.0037
Onchocerca volvulus 0.0039 0.0066 0.0192
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0059 0.0063
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0149 0.0402 0.4427
Brugia malayi glutathione reductase 0.005 0.0099 0.0107
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.002 0.0009 0.0009
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0025 0.0023 0.0173
Loa Loa (eye worm) hypothetical protein 0.0299 0.0863 0.0925
Loa Loa (eye worm) heat shock protein 90 0.0026 0.0027 0.0024
Loa Loa (eye worm) hypothetical protein 0.0299 0.0863 0.0925
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0315 0.0335
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0022 0.0013 0.003
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0201 0.0563 0.4272
Brugia malayi RNA binding protein 0.0063 0.0139 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0263 0.0751 0.2513
Echinococcus granulosus importin subunit beta 1 0.003 0.004 0.0043
Entamoeba histolytica heat shock protein 90, putative 0.0026 0.0027 0.0205
Echinococcus multilocularis muscleblind protein 0.1105 0.3331 0.3331
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0025 0.0023 0.0159
Schistosoma mansoni lipoxygenase 0.0115 0.0298 0.0321
Schistosoma mansoni lamin 0.0026 0.0028 0.003
Loa Loa (eye worm) aldehyde dehydrogenase 0.0025 0.0023 0.002
Echinococcus granulosus lamin dm0 0.0026 0.0028 0.003
Plasmodium falciparum thioredoxin reductase 0.005 0.0099 0.1323
Echinococcus granulosus guanine nucleotide binding protein subunit 0.002 0.0009 0.001
Giardia lamblia Histone acetyltransferase GCN5 0.0085 0.0207 0.3678
Mycobacterium ulcerans acetylornithine aminotransferase 0.0022 0.0013 0.01
Schistosoma mansoni heat shock protein 0.0026 0.0027 0.0029
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0067
Trypanosoma brucei glycerol uptake protein, putative 0.0263 0.0751 0.8267
Loa Loa (eye worm) cytochrome P450 0.0043 0.0078 0.0079
Loa Loa (eye worm) hypothetical protein 0.1105 0.3331 0.3587
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0066 0.0192
Entamoeba histolytica acetyltransferase, GNAT family 0.0085 0.0207 0.2304
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0025 0.0023 0.0039
Echinococcus granulosus guanine nucleotide binding protein G protein 0.002 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0067
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0099 0.0172
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0025 0.0023 0.025
Toxoplasma gondii hypothetical protein 0.0263 0.0751 0.5697
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.0449 0.0449
Leishmania major cytochrome p450-like protein 0.0043 0.0078 0.0593
Trichomonas vaginalis conserved hypothetical protein 0.0263 0.0751 0.2513
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0067
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0189 0.2519
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0043 0.0078 0.0593
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0103
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0095 0.0098
Schistosoma mansoni zinc finger protein 0.3047 0.9279 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0113 0.0294 0.333
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.015
Echinococcus granulosus guanine nucleotide binding protein subunit 0.002 0.0009 0.001
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0095 0.0095
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0025 0.0023 0.0025
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0043 0.0078 0.0593
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0009 0.001
Schistosoma mansoni retinoic acid receptor RXR 0.0083 0.02 0.0216
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0067
Mycobacterium ulcerans L-lysine aminotransferase 0.0022 0.0013 0.01
Schistosoma mansoni hypothetical protein 0.0021 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0067
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0201 0.0563 1
Onchocerca volvulus 0.0127 0.0338 0.1102
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0078 0.0085
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0023 0.0025
Trichomonas vaginalis penicillin-binding protein, putative 0.0299 0.0863 0.2885
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0056 0.006
Brugia malayi nuclear hormone receptor family member odr-7 0.0039 0.0066 0.0072
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.047 0.1387 0.1494
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0263 0.0751 0.0751
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0043 0.0078 0.0593
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0201 0.0563 0.0607
Plasmodium vivax ornithine aminotransferase, putative 0.0022 0.0013 0.0152
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0009 0.001
Echinococcus granulosus GPCR family 2 0.0048 0.0095 0.0103
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.0131 0.1743
Toxoplasma gondii heat shock protein HSP90 0.0026 0.0027 0.0203
Onchocerca volvulus 0.0299 0.0863 0.2863
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0066 0.0066
Schistosoma mansoni hypothetical protein 0.0033 0.0047 0.005
Onchocerca volvulus Protein ultraspiracle homolog 0.0083 0.02 0.064
Onchocerca volvulus Huntingtin homolog 0.0255 0.0729 0.2416
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0029 0.0096
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0058 0.0058
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0151 0.0411 0.3113
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0009 0.0031
Loa Loa (eye worm) hypothetical protein 0.0299 0.0863 0.0925
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0022 0.0013 0.0023
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0066 0.0072
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0025 0.0023 0.025
Schistosoma mansoni inositol monophosphatase 0.0036 0.0058 0.0062
Brugia malayi hypothetical protein 0.0043 0.0078 0.0085
Schistosoma mansoni trimeric G-protein alpha o subunit 0.002 0.0009 0.001
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0402 0.3051
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0126 0.0333 0.0575
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0448 0.1319 1
Echinococcus multilocularis endoplasmin 0.0021 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0029 0.0096
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0083 0.02 0.02
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0016 0.0016
Mycobacterium tuberculosis Probable dehydrogenase 0.0113 0.0294 0.0508
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.0131 0.1417
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0023 0.0025
Brugia malayi Niemann-Pick C1 protein precursor 0.0079 0.0188 0.0203
Brugia malayi nuclear receptor NHR-88 0.0083 0.02 0.0216
Loa Loa (eye worm) hypothetical protein 0.0079 0.0189 0.0199
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0005
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.002 0.0009 0.0005
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0039 0.0066 0.0072
Echinococcus granulosus histone acetyltransferase KAT2B 0.0095 0.0238 0.0257
Brugia malayi ecdysteroid receptor 0.0083 0.02 0.0216
Toxoplasma gondii cytochrome p450 superfamily protein 0.0043 0.0078 0.0593
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0043 0.0078 0.0593
Brugia malayi F/Y-rich N-terminus family protein 0.0042 0.0077 0.0083
Echinococcus multilocularis survival motor neuron protein 1 0.0501 0.1482 0.1482
Trypanosoma brucei Heat shock protein 83, putative 0.0026 0.0027 0.0294
Brugia malayi CHE-14 protein 0.0034 0.0051 0.0054
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.002 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0083 0.02 0.0211
Loa Loa (eye worm) inositol-1 0.0036 0.0058 0.0057
Brugia malayi MBOAT family protein 0.0263 0.0751 0.081
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0083 0.02 0.0216
Loa Loa (eye worm) hypothetical protein 0.0044 0.0081 0.0082
Brugia malayi Steroid receptor seven-up type 2 0.0083 0.02 0.0216
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0043 0.0078 0.0593
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0043 0.0078 0.0135
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0009 0.0103
Onchocerca volvulus 0.0039 0.0066 0.0192
Schistosoma mansoni cytochrome P450 0.0043 0.0078 0.0084
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0314 0.0909 1
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0025 0.0023 0.0025
Echinococcus multilocularis microtubule associated protein 2 0.1463 0.4427 0.4427
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0005
Schistosoma mansoni cpg binding protein 0.0126 0.0333 0.0359
Loa Loa (eye worm) endoplasmin 0.0026 0.0027 0.0024
Echinococcus granulosus sterol regulatory element binding protein 0.0034 0.0051 0.0054
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0041 0.0073 0.0073
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0025 0.0023 0.0173
Echinococcus granulosus neuropeptide s receptor 0.1008 0.3035 0.3271
Schistosoma mansoni survival motor neuron protein 0.0102 0.026 0.0281
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0201 0.0563 0.0607
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0062 0.0138 0.1047
Echinococcus multilocularis mitogen activated protein kinase 3 0.0111 0.0287 0.0287
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0059 0.0196
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0201 0.0563 0.0563
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0005
Entamoeba histolytica hypothetical protein, conserved 0.0263 0.0751 0.8631
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.026 0.0281
Echinococcus multilocularis zinc finger protein 0.0034 0.0052 0.0052
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0023 0.025
Loa Loa (eye worm) hypothetical protein 0.0044 0.0081 0.0082
Loa Loa (eye worm) hypothetical protein 0.0263 0.0751 0.0805
Schistosoma mansoni inositol monophosphatase 0.0036 0.0058 0.0062
Loa Loa (eye worm) hypothetical protein 0.0299 0.0863 0.0925
Echinococcus multilocularis Niemann Pick C1 protein 0.0112 0.0291 0.0291
Mycobacterium leprae PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT 0.0025 0.0023 0.0143
Trypanosoma brucei cytochrome P450, putative 0.0062 0.0138 0.152
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0083 0.02 0.0216
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.004 0.0304
Echinococcus granulosus cpg binding protein 0.0126 0.0333 0.0359
Schistosoma mansoni hypothetical protein 0.0048 0.0095 0.0103
Echinococcus granulosus expressed protein 0.002 0.0009 0.001
Brugia malayi TAR-binding protein 0.0063 0.0139 0.015
Echinococcus multilocularis neuropeptide receptor A26 0.1008 0.3035 0.3035
Plasmodium vivax hypothetical protein, conserved 0.0299 0.0863 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.047 0.1387 0.1387
Giardia lamblia DINP protein human, muc B family 0.002 0.0009 0.0166
Schistosoma mansoni hypothetical protein 0.0043 0.0078 0.0085
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.002 0.0009 0.0009
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0009 0.001
Trichomonas vaginalis ran, putative 0.0022 0.0016 0.0052
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0067
Brugia malayi intermediate filament protein 0.0026 0.0028 0.003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.02 0.0216
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0029 0.0096
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0315 0.0335
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0043 0.0078 0.0135
Loa Loa (eye worm) histone methyltransferase 0.0041 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0096 0.0241 0.0255
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.008
Brugia malayi Pre-SET motif family protein 0.0127 0.0338 0.0364
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0059 0.0063
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.002 0.0009 0.001
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0059 0.0445
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0034 0.0051 0.0051
Echinococcus granulosus guanine nucleotide binding protein G protein 0.002 0.0009 0.001
Leishmania major cytochrome p450-like protein 0.0043 0.0078 0.0593
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0059 0.0196
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0005
Echinococcus multilocularis 0.0043 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0067
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0287 0.0961
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0025 0.0023 0.0023
Echinococcus granulosus o acyltransferase membrane bound domain 0.0263 0.0751 0.081
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0263 0.0751 0.0751
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Brugia malayi hypothetical protein 0.0039 0.0066 0.0072
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.002 0.0009 0.001
Loa Loa (eye worm) cytochrome P450 family protein 0.0062 0.0138 0.0144
Echinococcus granulosus heat shock protein 90 0.0021 0.0011 0.0011
Plasmodium vivax glutathione reductase, putative 0.005 0.0099 0.1152
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0005
Echinococcus granulosus mitogen activated protein kinase 0.0111 0.0287 0.031
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0043 0.0078 0.0593
Schistosoma mansoni RAR-like nuclear receptor 0.0083 0.02 0.0216
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0043 0.0078 0.0593
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0029 0.0096
Brugia malayi Calcitonin receptor-like protein seb-1 0.0153 0.0415 0.0447
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.02 0.0216
Onchocerca volvulus 0.0117 0.0307 0.0999
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0025 0.0023 0.0046
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.008
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0083 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0067
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0201 0.0563 0.6199
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0022 0.0013 0.0023
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0299 0.0863 0.093
Schistosoma mansoni eyes absent homolog 0.0096 0.0241 0.026
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0078 0.0085
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0448 0.1319 0.1319
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0025 0.0023 0.0025
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.0131 0.1441
Brugia malayi diacylglycerol acyltransferase 0.0263 0.0751 0.081
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0034 0.0051 0.0055
Brugia malayi Muscleblind-like protein 0.1105 0.3331 0.359
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0025 0.0023 0.0173
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0201 0.0563 0.0563
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0029 0.0096
Entamoeba histolytica hypothetical protein 0.0301 0.0869 1
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0059 0.0059
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0043 0.0078 0.0135
Echinococcus granulosus mitogen activated protein kinase 3 0.0111 0.0287 0.031
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0009 0.0009
Trichomonas vaginalis penicillin-binding protein, putative 0.0299 0.0863 0.2885
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0025 0.0023 0.0039
Echinococcus multilocularis heat shock protein 0.0026 0.0027 0.0027
Echinococcus multilocularis musashi 0.0026 0.0028 0.0028
Echinococcus granulosus microtubule associated protein 2 0.1463 0.4427 0.4771
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0099 0.0102
Loa Loa (eye worm) hypothetical protein 0.0044 0.0081 0.0082
Schistosoma mansoni coup transcription factor 0.0083 0.02 0.0216
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0153 0.0415 0.0447
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0051 0.0169
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0043 0.0078 0.0135
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0009 0.0031
Echinococcus multilocularis snurportin 1 0.0323 0.0938 0.0938
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0263 0.0751 0.081
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0083 0.0908
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0081 0.0087
Echinococcus granulosus zinc finger protein 0.0034 0.0052 0.0056
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0127 0.0338 0.256
Echinococcus multilocularis expressed conserved protein 0.0074 0.0173 0.0173
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0099 0.1152
Trichomonas vaginalis D-aminoacylase, putative 0.0299 0.0863 0.2885
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.002 0.0009 0.0009
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.002 0.0009 0.001
Echinococcus multilocularis GPCR, family 2 0.0048 0.0095 0.0095
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0029 0.0096
Loa Loa (eye worm) hypothetical protein 0.0026 0.0027 0.0024
Echinococcus multilocularis dnaJ subfamily B 0.127 0.3836 0.3836
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0038
Echinococcus granulosus ecdysone induced protein 78C 0.0083 0.02 0.0216
Leishmania major glycerol uptake protein, putative 0.0263 0.0751 0.5697
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0201 0.0563 0.1884
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0029 0.0096
Echinococcus multilocularis nuclear receptor nhr 48 0.0039 0.0066 0.0066
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0058 0.0063
Echinococcus granulosus dna polymerase eta 0.002 0.0009 0.001
Brugia malayi Cytochrome P450 family protein 0.0062 0.0138 0.0149
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0083 0.02 0.0211
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0059 0.0196
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0025 0.0023 0.0039
Entamoeba histolytica hypothetical protein 0.0301 0.0869 1
Trypanosoma brucei heat shock protein, putative 0.0026 0.0027 0.0294
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.002 0.0009 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.0448 0.1319 0.1421
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Echinococcus granulosus tumor protein p63 0.1384 0.4187 0.4512
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0299 0.0863 0.093
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0201 0.0563 0.6199
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0009 0.0071
Echinococcus multilocularis Niemann Pick C1 protein 0.0079 0.0188 0.0188
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0044 0.0081 0.0082
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0043 0.0078 0.0135
Loa Loa (eye worm) hypothetical protein 0.0083 0.02 0.0211
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.0025 0.0023 0.0143
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0025 0.0023 0.0159
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.002 0.0009 0.003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0131 0.1518
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0263 0.0751 0.5697
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.002 0.0009 0.0009
Echinococcus multilocularis sterol O acyltransferase 1 0.0263 0.0751 0.0751
Echinococcus multilocularis expressed protein 0.002 0.0009 0.0009
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Plasmodium vivax endoplasmin, putative 0.0026 0.0027 0.031
Leishmania major cytochrome p450-like protein 0.0062 0.0138 0.1047
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0023 0.0025
Leishmania major glycerol uptake protein, putative 0.0263 0.0751 0.5697
Echinococcus multilocularis sterol regulatory element binding protein 0.0034 0.0051 0.0051
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0009 0.0103
Schistosoma mansoni cpg binding protein 0.0117 0.0307 0.0331
Schistosoma mansoni loxhd1 0.0043 0.0078 0.0085
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.012 0.0316 0.034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0029 0.0096
Echinococcus granulosus o acyltransferase membrane bound domain 0.0263 0.0751 0.081
Schistosoma mansoni ap endonuclease 0.006 0.0131 0.0141
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0043 0.0078 0.0593
Brugia malayi ecdysone receptor 0.0039 0.0066 0.0072
Onchocerca volvulus 0.0043 0.0078 0.0233
Schistosoma mansoni hypothetical protein 0.0048 0.0095 0.0103
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0059 0.0445
Mycobacterium ulcerans aldehyde dehydrogenase 0.0448 0.1319 1
Echinococcus granulosus cytochrome P450 2K1 0.0043 0.0078 0.0084
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0025 0.0023 0.0025
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.0027 0.0294
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0314 0.0909 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.006 0.0131 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.047 0.1387 0.1494
Brugia malayi hypothetical protein 0.002 0.0009 0.001
Mycobacterium ulcerans esterase/lipase LipP 0.0299 0.0863 0.654
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0025 0.0023 0.025
Schistosoma mansoni hypothetical protein 0.0048 0.0095 0.0103
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0081 0.0087
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.0131 0.0993
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0009 0.0103
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0043 0.0078 0.0593
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0083 0.02 0.0216
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.0027 0.0294
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0022 0.0013 0.003
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0263 0.0751 0.8631
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0059 0.0196
Entamoeba histolytica hypothetical protein 0.0301 0.0869 1
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0022 0.0013 0.01
Trypanosoma brucei glucosidase, putative 0.0036 0.0059 0.0646
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0025 0.0023 0.0173
Schistosoma mansoni alpha glucosidase 0.0036 0.0059 0.0063
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0022 0.0013 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.047 0.1387 0.1494
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0043 0.0078 0.0135
Echinococcus multilocularis protein patched 0.0034 0.0051 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0103
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.0449 0.0449
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.02 0.0216
Mycobacterium tuberculosis Probable lipase LipE 0.0299 0.0863 0.1488
Toxoplasma gondii LsmAD domain-containing protein 0.0079 0.0189 0.1435
Mycobacterium tuberculosis Probable reductase 0.0113 0.0294 0.0508
Mycobacterium tuberculosis Probable hydrolase 0.0299 0.0863 0.1488
Schistosoma mansoni rab6-interacting 0.0043 0.0078 0.0085
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0025 0.0023 0.0173
Brugia malayi nuclear receptor NHR-88 0.0039 0.0066 0.0072
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.002 0.0009 0.001
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0025 0.0023 0.0025
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0039 0.0066 0.0067
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0111 0.0287 0.3162
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0009 0.0103
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0039 0.0066 0.0072
Echinococcus granulosus lamin 0.0026 0.0028 0.003
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0287 0.3162
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0043 0.0078 0.0135
Brugia malayi MH2 domain containing protein 0.012 0.0315 0.034
Schistosoma mansoni ap endonuclease 0.006 0.0131 0.0141
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0039 0.0066 0.0072
Loa Loa (eye worm) MBOAT family protein 0.3047 0.9279 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0046 0.0419
Schistosoma mansoni nuclear hormone receptor 0.0083 0.02 0.0216
Schistosoma mansoni importin beta-1 0.003 0.004 0.0043
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.002 0.0009 0.001
Brugia malayi nuclear hormone receptor family member nhr-6 0.0039 0.0066 0.0072
Brugia malayi nuclear receptor RXR 0.0044 0.0081 0.0087
Schistosoma mansoni hypothetical protein 0.0104 0.0267 0.0288
Schistosoma mansoni hypothetical protein 0.0033 0.0047 0.005
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0009 0.003
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0083 0.02 0.0211
Onchocerca volvulus 0.0026 0.0028 0.0063
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0009 0.001
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0009 0.0103
Loa Loa (eye worm) bromodomain containing protein 0.0025 0.0025 0.0022
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0263 0.0751 0.081
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0011 0.0035
Echinococcus multilocularis neuropeptide s receptor 0.1008 0.3035 0.3035
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0009 0.0103
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0011 0.0035
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0078 0.008
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0448 0.1319 0.1421
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0083 0.02 0.0216
Schistosoma mansoni sterol O-acyltransferase 1 0.0263 0.0751 0.081
Schistosoma mansoni alpha-glucosidase 0.0141 0.0379 0.0409
Brugia malayi Nuclear hormone receptor-like 1 0.0083 0.02 0.0216
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.015
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0079 0.0188 0.2079
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0099 0.1094
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0175 0.0189
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.0078 0.0861
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0034 0.0051 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0083 0.02 0.0216
Toxoplasma gondii heat shock protein 90, putative 0.0026 0.0027 0.0203
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0299 0.0863 0.654
Schistosoma mansoni hypothetical protein 0.0033 0.0047 0.005
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0025 0.0023 0.0173
Schistosoma mansoni ran 0.0022 0.0016 0.0017
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0013 0.0014
Loa Loa (eye worm) CXXC zinc finger family protein 0.0117 0.0307 0.0326
Echinococcus granulosus nuclear receptor nhr 48 0.0039 0.0066 0.0072
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0046 0.008
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0112 0.1233
Loa Loa (eye worm) hypothetical protein 0.0263 0.0751 0.0805
Entamoeba histolytica hypothetical protein 0.0025 0.0023 0.0156
Brugia malayi nuclear receptor NHR-67 0.0039 0.0066 0.0072
Trypanosoma cruzi hypothetical protein, conserved 0.0299 0.0863 0.9491
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0025 0.0023 0.0173
Trypanosoma brucei heat shock protein 90, putative 0.0026 0.0027 0.0294
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0009 0.003
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0175 0.0175
Entamoeba histolytica vacuolar protein sorting 26 0.0263 0.0751 0.8631
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0287 0.0961
Echinococcus multilocularis importin subunit beta 1 0.003 0.004 0.004
Loa Loa (eye worm) MBOAT family protein 0.0263 0.0751 0.0805
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0317 0.0919 0.099
Loa Loa (eye worm) DR-78 0.0039 0.0066 0.0067
Trypanosoma cruzi hypothetical protein, conserved 0.0299 0.0863 0.9491
Loa Loa (eye worm) hypothetical protein 0.0104 0.0267 0.0283
Entamoeba histolytica heat shock protein 90, putative 0.0026 0.0027 0.0205
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0111 0.0287 0.0305
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0039 0.0066 0.0072
Brugia malayi hypothetical protein 0.0079 0.0189 0.0204
Echinococcus granulosus heat shock protein 0.0026 0.0027 0.0029
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0059 0.0577
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0058 0.0636
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.002 0.0009 0.0009
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.3047 0.9279 0.9279
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0043 0.0078 0.0135
Schistosoma mansoni polycystin 1-related 0.0043 0.0078 0.0085
Loa Loa (eye worm) nuclear receptor NHR-67 0.0039 0.0066 0.0067
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.047 0.1387 0.1494
Echinococcus multilocularis cpg binding protein 0.0126 0.0333 0.0333
Loa Loa (eye worm) MBOAT family protein 0.0263 0.0751 0.0805
Mycobacterium ulcerans beta-lactamase 0.0299 0.0863 0.654
Loa Loa (eye worm) hypothetical protein 0.1105 0.3331 0.3587
Trypanosoma cruzi cytochrome P450, putative 0.0062 0.0138 0.152
Leishmania major aldehyde dehydrogenase, putative 0.0025 0.0023 0.0173
Plasmodium vivax SET domain containing protein 0.0017 0 0.0002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0237 0.0674 0.5109
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0066 0.0066
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0013 0.01
Echinococcus granulosus expressed conserved protein 0.0074 0.0173 0.0187
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0059 0.0646
Trypanosoma brucei protein kinase, putative 0.0111 0.0287 0.3162
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0025 0.0023 0.025
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0025 0.0023 0.0039
Echinococcus granulosus snurportin 1 0.0323 0.0938 0.1011
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0058 0.4415
Trypanosoma cruzi heat shock protein 90, putative 0.0021 0.0011 0.0116
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0009 0.0071
Mycobacterium tuberculosis Probable lipase LipD 0.0299 0.0863 0.1488
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0201 0.0563 0.0607
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0263 0.0751 0.0751
Echinococcus granulosus FTZ F1 alpha 0.0083 0.02 0.0216
Brugia malayi nuclear hormone receptor 0.0083 0.02 0.0216
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0095 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0103
Schistosoma mansoni thyroid hormone receptor 0.0083 0.02 0.0216
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0103
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0254 0.0725 0.0781
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0025 0.0023 0.025
Leishmania major glycerol uptake protein, putative 0.0263 0.0751 0.5697
Schistosoma mansoni heat shock protein 0.0026 0.0027 0.0029
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0013 0.01
Echinococcus multilocularis dna polymerase eta 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0083 0.02 0.0211
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0025 0.0023 0.025
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0058 0.0062
Brugia malayi hypothetical protein 0.0241 0.0686 0.0739
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0025 0.0023 0.0025
Onchocerca volvulus 0.0299 0.0863 0.2863
Echinococcus granulosus survival motor neuron protein 1 0.0501 0.1482 0.1597
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0009 0.0103
Loa Loa (eye worm) hypothetical protein 0.0083 0.02 0.0211
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0025 0.0023 0.0173
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0025 0.0023 0.025
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0025 0.0023 0.0173
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0066 0.0072
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0066 0.0072
Brugia malayi Pre-SET motif family protein 0.0873 0.2622 0.2826
Onchocerca volvulus Bile acid receptor homolog 0.0083 0.02 0.064
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.0078 0.0861
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0066 0.0072
Mycobacterium leprae putative cytochrome p450 0.0043 0.0078 0.0794
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.015
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0078 0.0078
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0113 0.0294 0.0508
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0083 0.02 0.0216
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0301 0.0869 0.0869
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0099 0.0099
Leishmania major mitochondrial DNA polymerase beta 0.0314 0.0909 0.6891
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.002 0.0009 0.003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0058 0.0193
Schistosoma mansoni zinc finger protein 0.0039 0.0066 0.0072
Mycobacterium tuberculosis Possible penicillin-binding protein 0.191 0.5795 1
Echinococcus multilocularis FTZ F1 alpha 0.0083 0.02 0.02
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0078 0.0078
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0263 0.0751 0.081
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0022 0.0013 0.1004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0083 0.02 0.0216
Brugia malayi Glycosyl hydrolases family 31 protein 0.0164 0.0449 0.0484
Loa Loa (eye worm) hypothetical protein 0.0201 0.0563 0.0603
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0023 0.025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0095 0.0238 0.0796
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0028 0.003
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0067
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0488 0.1442 0.155
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0034 0.0051 0.005
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0083 0.0908
Mycobacterium tuberculosis Conserved hypothetical protein 0.0165 0.0454 0.0783
Schistosoma mansoni lamin 0.0026 0.0028 0.003
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0023 0.0248
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0131 0.0438
Toxoplasma gondii hypothetical protein 0.0051 0.0102 0.0776
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0025 0.0023 0.0023
Mycobacterium ulcerans lipase LipD 0.0299 0.0863 0.654
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0113 0.0294 0.0508
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0043 0.0078 0.0135
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0263 0.0751 0.081
Treponema pallidum heat shock protein 90 0.0021 0.0011 0.014
Loa Loa (eye worm) cytochrome P450 family protein 0.0168 0.0462 0.0493
Echinococcus multilocularis heat shock protein 90 0.0026 0.0027 0.0027
Trichomonas vaginalis porcupine, putative 0.0263 0.0751 0.2513
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0083 0.02 0.0216
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0025 0.0023 0.025
Brugia malayi G-protein alpha subunit 0.002 0.0009 0.001
Schistosoma mansoni thyroid hormone receptor 0.0083 0.02 0.0216
Echinococcus granulosus Niemann Pick C1 protein 0.0112 0.0291 0.0314
Brugia malayi Bromodomain containing protein 0.0046 0.0089 0.0096
Echinococcus granulosus histone lysine methyltransferase setb 0.0145 0.039 0.0421
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0263 0.0751 0.8631
Giardia lamblia Alcohol dehydrogenase 0.0025 0.0023 0.0404
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.002 0.0009 0.003
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0043 0.0078 0.0135
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0023 0.0075
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0131 0.1743
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0025 0.0023 0.0173
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0025 0.0023 0.0173
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0201 0.0563 0.1884
Onchocerca volvulus 0.0994 0.299 1
Echinococcus multilocularis dna polymerase kappa 0.002 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0043 0.0078 0.0593
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0058 0.0636
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0095 0.0103
Brugia malayi MBOAT family protein 0.0263 0.0751 0.081
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0066 0.0072
Schistosoma mansoni hypothetical protein 0.0035 0.0056 0.006
Brugia malayi MBOAT family protein 0.0263 0.0751 0.081
Loa Loa (eye worm) hypothetical protein 0.0145 0.039 0.0416
Loa Loa (eye worm) hypothetical protein 0.0083 0.02 0.0211
Loa Loa (eye worm) hypothetical protein 0.0153 0.0415 0.0443
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0066 0.0072
Wolbachia endosymbiont of Brugia malayi bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 0.0025 0.0023 0.1738
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0058 0.0438
Leishmania major aldehyde dehydrogenase, putative 0.0025 0.0023 0.0173
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0023 0.0075
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0025 0.0023 0.0173
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0201 0.0563 0.6445
Brugia malayi MBOAT family protein 0.3047 0.9279 1
Brugia malayi Bromodomain containing protein 0.009 0.0223 0.024
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0043 0.0078 0.0593
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.0131 0.0136
Schistosoma mansoni hypothetical protein 0.127 0.3836 0.4134
Loa Loa (eye worm) hypothetical protein 0.0501 0.1482 0.1593
Loa Loa (eye worm) hypothetical protein 0.0299 0.0863 0.0925
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0016 0.0012
Trypanosoma brucei heat shock protein, putative 0.0026 0.0027 0.0294
Schistosoma mansoni ran 0.0022 0.0016 0.0017
Plasmodium vivax SET domain protein, putative 0.0127 0.0338 0.3914
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0058 0.0438
Echinococcus granulosus ubiquitin specific protease 41 0.0201 0.0563 0.0607
Leishmania major hypothetical protein, conserved 0.0079 0.0189 0.1435
Brugia malayi Inositol-1 0.0036 0.0058 0.0062
Leishmania major hypothetical protein, conserved 0.0263 0.0751 0.5697
Onchocerca volvulus 0.0299 0.0863 0.2863
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0016 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0201 0.0563 0.1884
Mycobacterium leprae Probable lipase LipE 0.0299 0.0863 1
Echinococcus granulosus sterol O acyltransferase 1 0.0263 0.0751 0.081
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0009 0.003
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0314 0.0909 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0066 0.0192
Echinococcus granulosus beta LACTamase domain containing family member 0.0299 0.0863 0.093
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0301 0.0869 0.0937
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.047 0.1387 0.1387
Echinococcus multilocularis lamin 0.0026 0.0028 0.0028
Schistosoma mansoni alpha-glucosidase 0.0141 0.0379 0.0409
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0059 0.0577
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0103
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0037 0.004
Brugia malayi steroid hormone receptor 0.0083 0.02 0.0216
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0127 0.0338 0.0338
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0043 0.0078 0.0135
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0126 0.0333 0.3785
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0016 0.0171
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.02 0.0216
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0111 0.0287 0.2179
Echinococcus granulosus histone acetyltransferase KAT2B 0.0306 0.0885 0.0953
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0023 0.0025
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Loa Loa (eye worm) hypothetical protein 0.0083 0.02 0.0211
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0078 0.091
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0145 0.039 0.039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0127 0.0338 0.0364
Giardia lamblia Kinase, CMGC MAPK 0.0111 0.0287 0.5102
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0067
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0083 0.02 0.0216
Loa Loa (eye worm) cytochrome P450 family protein 0.0062 0.0138 0.0144
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0005
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0022 0.0013 0.01
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.002 0.0009 0.001
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0025 0.0023 0.0039
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0022 0.0013 0.003
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0025 0.0023 0.025
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0059 0.0196
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0066 0.0072
Loa Loa (eye worm) hypothetical protein 0.0044 0.0081 0.0082
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0078 0.0078
Brugia malayi aldehyde dehydrogenase 0.0025 0.0023 0.0025
Schistosoma mansoni hypothetical protein 0.0263 0.0751 0.081
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0025 0.0023 0.025
Schistosoma mansoni hypothetical protein 0.0048 0.0095 0.0103
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0095 0.0095
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.015
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0009 0.0071
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0058 0.0567
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0025 0.0023 0.0159
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0025 0.0023 0.0173
Schistosoma mansoni niemann-pick C1 (NPC1) 0.008 0.0192 0.0207
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0083 0.02 0.0216
Plasmodium falciparum histone acetyltransferase GCN5 0.0085 0.0207 0.2758
Onchocerca volvulus 0.0026 0.0028 0.0063
Plasmodium vivax heat shock protein 86, putative 0.0026 0.0027 0.031
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.015
Brugia malayi beta-lactamase 0.0299 0.0863 0.093
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0151 0.0411 0.0708
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0263 0.0751 1
Echinococcus granulosus RUN 0.0043 0.0078 0.0085
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.047 0.1387 0.1494
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0299 0.0863 0.0925
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Brugia malayi photoreceptor-specific nuclear receptor 0.0083 0.02 0.0216
Schistosoma mansoni intermediate filament proteins 0.0026 0.0028 0.003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0058 0.0193
Trypanosoma brucei heat shock protein, putative 0.0026 0.0027 0.0294
Toxoplasma gondii exonuclease III APE 0.006 0.0131 0.0993
Echinococcus granulosus mixed lineage leukemia protein mll 0.0034 0.0051 0.0055
Echinococcus granulosus dna polymerase kappa 0.002 0.0009 0.001
Trypanosoma cruzi glycerol uptake protein, putative 0.0263 0.0751 0.8267
Leishmania major glycerol uptake protein, putative 0.0263 0.0751 0.5697
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.0131 0.0226
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0263 0.0751 0.081
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0263 0.0751 0.081
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0025 0.0023 0.0039
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0043 0.0078 0.0135
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0016 0.0276
Trypanosoma brucei trypanothione reductase 0.005 0.0099 0.1094
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0083 0.02 0.0216
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0083 0.02 0.02
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0022 0.0013 0.0023
Schistosoma mansoni bromodomain containing protein 0.0078 0.0186 0.0201
Onchocerca volvulus 0.0263 0.0751 0.249
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0127 0.0338 0.0364
Plasmodium falciparum glutathione reductase 0.005 0.0099 0.1323
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0039 0.0066 0.0066
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0099 0.0107
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0058 0.0438
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0043 0.0078 0.0593
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0043 0.0078 0.0593
Entamoeba histolytica Ran family GTPase 0.0022 0.0016 0.0075
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0263 0.0751 0.081
Mycobacterium leprae conserved hypothetical protein 0.0299 0.0863 1
Loa Loa (eye worm) hypothetical protein 0.0096 0.0241 0.0255
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0044 0.0081 0.0081
Brugia malayi Thioredoxin reductase 0.005 0.0099 0.0107
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0448 0.1319 0.2276
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0029 0.0096
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0263 0.0751 0.0805
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.0131 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0029 0.0096
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0263 0.0751 0.081
Mycobacterium tuberculosis Conserved protein 0.0299 0.0863 0.1488
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0067
Trypanosoma brucei heat shock protein, putative 0.0026 0.0027 0.0294
Echinococcus granulosus heat shock protein 90 0.0026 0.0027 0.0029
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.3047 0.9279 1
Schistosoma mansoni zinc finger protein 0.0034 0.0052 0.0056
Plasmodium vivax ataxin-2 like protein, putative 0.0079 0.0189 0.2194
Echinococcus granulosus intermediate filament protein 0.0026 0.0028 0.003
Trypanosoma cruzi heat shock protein 90, putative 0.0026 0.0027 0.0294
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0029 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0103
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0111 0.0287 0.3162
Loa Loa (eye worm) beta-lactamase 0.0299 0.0863 0.0925
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0083 0.02 0.0211
Giardia lamblia Grp94/Hsp90 0.0021 0.0011 0.0187
Brugia malayi heat shock protein 90 0.0026 0.0027 0.0029
Brugia malayi Endoplasmin precursor 0.0026 0.0027 0.0029
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0023 0.025
Brugia malayi conserved hypotetical protein 0.0039 0.0066 0.0072
Mycobacterium ulcerans heat shock protein 90 0.0021 0.0011 0.008
Loa Loa (eye worm) RNA binding protein 0.0063 0.0139 0.0145
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0067
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.002 0.0009 0.001
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0041 0.0073 0.0078
Echinococcus multilocularis ubiquitin specific protease 41 0.0201 0.0563 0.0563
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0263 0.0751 0.0751
Brugia malayi Hhat protein 0.0263 0.0751 0.081
Schistosoma mansoni DNA polymerase eta 0.002 0.0009 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0029 0.0096
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.002
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0078 0.1044
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.0131 0.2325
Trichomonas vaginalis conserved hypothetical protein 0.0263 0.0751 0.2513
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0192 0.0534 0.0534
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0028 0.0025
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0023 0.025
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0039 0.0066 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0083 0.02 0.0216
Echinococcus granulosus muscleblind protein 0.1105 0.3331 0.359
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0043 0.0078 0.0135
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0043 0.0078 0.0861
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0043 0.0078 0.0593
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0013 0.0013
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0263 0.0751 0.0751
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0043 0.0078 0.0593
Brugia malayi tailless protein 0.0039 0.0066 0.0072
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.004 0.0441
Mycobacterium leprae Conserved hypothetical protein 0.0043 0.0078 0.0794
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0299 0.0863 0.093
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0083 0.02 0.0216
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0029 0.0096
Loa Loa (eye worm) hypothetical protein 0.0079 0.0188 0.0198
Leishmania major aldehyde dehydrogenase, putative 0.0025 0.0023 0.0173
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0131 0.0438
Echinococcus granulosus tar DNA binding protein 0.0063 0.0139 0.015
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0083 0.02 0.0216
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0287 0.0961
Toxoplasma gondii thioredoxin reductase 0.005 0.0099 0.0754
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.0131 0.0993
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0025 0.0023 0.0173
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0058 0.0636
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0095 0.0238 0.0796
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0043 0.0078 0.0593
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0078 0.0085
Schistosoma mansoni hypothetical protein 0.0043 0.0078 0.0084
Brugia malayi hypothetical protein 0.0043 0.0078 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.02 0.0216
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0022 0.0013 0.01
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0025 0.0023 0.002
Echinococcus granulosus endoplasmin 0.0021 0.0011 0.0011
Trichomonas vaginalis esterase, putative 0.0299 0.0863 0.2885
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0139 0.0145
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0139 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0103
Echinococcus granulosus thyroid hormone receptor alpha 0.0039 0.0066 0.0072
Brugia malayi MAP kinase sur-1 0.0111 0.0287 0.031
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0025 0.0023 0.0173
Schistosoma mansoni cellular tumor antigen P53 0.0203 0.0568 0.0612
Loa Loa (eye worm) hypothetical protein 0.0263 0.0751 0.0805
Echinococcus granulosus Niemann Pick C1 protein 0.0079 0.0188 0.0203
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0299 0.0863 0.1488
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0029 0.0096
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0021 0.0011 0.008
Treponema pallidum alginate O-acetylation protein (algI) 0.0263 0.0751 1
Schistosoma mansoni nuclear receptor 0.0039 0.0066 0.0072
Brugia malayi Cytochrome P450 family protein 0.0043 0.0078 0.0084
Trypanosoma cruzi GUP1, putative 0.0263 0.0751 0.8267
Brugia malayi CXXC zinc finger family protein 0.0117 0.0307 0.0331
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0009 0.0016
Schistosoma mansoni GTP-binding protein alpha subunit 0.002 0.0009 0.001
Brugia malayi Doublecortin family protein 0.0043 0.0078 0.0085
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0323 0.0938 0.1006
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0043 0.0078 0.0135
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0192 0.0534 0.0576
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0151 0.0411 0.4694
Echinococcus multilocularis muscleblind protein 1 0.1105 0.3331 0.3331
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0083 0.0908
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0025 0.0023 0.0023
Trichomonas vaginalis helicase, putative 0.0027 0.0029 0.0096
Brugia malayi PHD-finger family protein 0.0039 0.0068 0.0073
Trichomonas vaginalis transmembrane protein nessy, putative 0.0263 0.0751 0.2513
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0043 0.0078 0.0593
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0022 0.0013 0.0014
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0009 0.003
Brugia malayi follicle stimulating hormone receptor 0.0488 0.1442 0.1554
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0113 0.0294 0.0508
Echinococcus granulosus ornithine aminotransferase 0.0022 0.0013 0.0014
Schistosoma mansoni microtubule-associated protein tau 0.1463 0.4427 0.4771
Loa Loa (eye worm) hypothetical protein 0.0071 0.0165 0.0173
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0083 0.0908
Onchocerca volvulus 0.0083 0.02 0.064
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.002 0.0009 0.001
Mycobacterium tuberculosis Conserved protein 0.0299 0.0863 0.1488
Toxoplasma gondii ABC1 family protein 0.0299 0.0863 0.654
Entamoeba histolytica hypothetical protein 0.0263 0.0751 0.8631
Brugia malayi acetyltransferase, GNAT family protein 0.0317 0.0919 0.099
Toxoplasma gondii aldehyde dehydrogenase 0.0448 0.1319 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.0568 0.0607
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0025 0.0023 0.0159
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0025 0.0023 0.025
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0263 0.0751 0.081
Loa Loa (eye worm) hypothetical protein 0.0048 0.0095 0.0098
Loa Loa (eye worm) acetyltransferase 0.0317 0.0919 0.0986
Brugia malayi Aldehyde dehydrogenase protein 4 0.0025 0.0023 0.0025
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0201 0.0563 0.6199
Brugia malayi hypothetical protein 0.0301 0.0869 0.0937
Brugia malayi orphan nuclear receptor NR2E1 0.0039 0.0066 0.0072
Onchocerca volvulus 0.0102 0.026 0.0843
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0111 0.0287 0.2179
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0164 0.0449 0.048
Echinococcus multilocularis protein dispatched 1 0.0038 0.0065 0.0065
Trypanosoma cruzi GUP1, putative 0.0263 0.0751 0.8267
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0095 0.0103
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0043 0.0078 0.0135
Brugia malayi Importin beta-1 subunit 0.003 0.004 0.0043
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.002 0.0009 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0081 0.0087
Plasmodium falciparum importin beta, putative 0.003 0.004 0.0533
Schistosoma mansoni GTP-binding protein alpha subunit 0.002 0.0009 0.001
Schistosoma mansoni nuclear receptor 0.0039 0.0066 0.0072
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0299 0.0863 0.1488
Mycobacterium tuberculosis Conserved protein 0.0299 0.0863 0.1488
Schistosoma mansoni hypothetical protein 0.0323 0.0938 0.1011
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0287 0.0961
Loa Loa (eye worm) hypothetical protein 0.0241 0.0686 0.0735
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0189 0.2083
Mycobacterium leprae PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDE 0.0025 0.0023 0.0143
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0025 0.0023 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0103
Echinococcus multilocularis RUN 0.0043 0.0078 0.0078
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0009 0.001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0095 0.0103
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0263 0.0751 0.5697
Trypanosoma brucei PAB1-binding protein , putative 0.0079 0.0189 0.2083
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0009 0.0003
Brugia malayi hypothetical protein 0.0051 0.0104 0.0112
Loa Loa (eye worm) hypothetical protein 0.0083 0.02 0.0211
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0028 0.0025
Trypanosoma brucei heat shock protein, putative 0.0026 0.0027 0.0294
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.0027 0.0294
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0025 0.0023 0.0173
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0066
Loa Loa (eye worm) hhat protein 0.0263 0.0751 0.0805
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.002 0.0009 0.001
Trypanosoma cruzi Heat shock protein 83, putative 0.0026 0.0027 0.0294
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0023 0.025
Trypanosoma brucei hypothetical protein, conserved 0.0299 0.0863 0.9491
Entamoeba histolytica hypothetical protein 0.0301 0.0869 1
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0043 0.0078 0.0593
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0025 0.0023 0.0039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0083 0.02 0.0211
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0103
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0016 0.0207
Leishmania major DNA polymerase kappa, putative 0.002 0.0009 0.0071
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0023 0.0025
Loa Loa (eye worm) hypothetical protein 0.0255 0.0729 0.0782
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0083 0.02 0.0211
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0059 0.0058
Loa Loa (eye worm) hypothetical protein 0.0263 0.0751 0.0805
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0113 0.0294 0.0508
Brugia malayi RNA, U transporter 1 0.0086 0.0211 0.0227
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0013 0.0013
Leishmania major trypanothione reductase 0.005 0.0099 0.0754
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0022 0.0013 0.0023
Onchocerca volvulus 0.0203 0.0568 0.1874
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0126 0.0333 0.0575
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0009 0.001
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.002 0.0009 0.0005
Leishmania major DNA polymerase eta, putative 0.002 0.0009 0.0071
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0021 0.0011 0.0018
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0058 0.0058
Plasmodium falciparum ornithine aminotransferase 0.0022 0.0013 0.0175
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0043 0.0078 0.0593
Mycobacterium ulcerans aldehyde dehydrogenase 0.0448 0.1319 1
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.002 0.0009 0.001
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0016 0.018
Onchocerca volvulus Huntingtin homolog 0.0255 0.0729 0.2416
Brugia malayi beta-lactamase family protein 0.0299 0.0863 0.093
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.0131 0.1441
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0021 0.0011 0.0011
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0009 0.001
Loa Loa (eye worm) hhat protein 0.0263 0.0751 0.0805
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0025 0.0023 0.0039
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0873 0.2622 0.2822
Leishmania major GTP-binding protein, putative 0.0022 0.0016 0.0118
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0287 0.031
Mycobacterium ulcerans aldehyde dehydrogenase 0.0025 0.0023 0.0173
Trypanosoma cruzi heat shock protein 85, putative 0.0021 0.0011 0.0116
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0044 0.0081 0.0087
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.002 0.0009 0.001
Loa Loa (eye worm) nuclear hormone receptor 0.0039 0.0066 0.0067
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0151 0.0411 0.1373
Trichomonas vaginalis D-aminoacylase, putative 0.0299 0.0863 0.2885
Brugia malayi Cytochrome P450 family protein 0.0168 0.0462 0.0498
Schistosoma mansoni endoplasmin 0.0026 0.0027 0.0029
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0016 0.0118
Schistosoma mansoni steroid hormone receptor ad4bp 0.0083 0.02 0.0216
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0009 0.0016
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0201 0.0563 0.0607
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0037 0.004
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0044 0.0081 0.0087
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0009 0.0103
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0263 0.0751 0.0751
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0025 0.0023 0.0173
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0099
Trypanosoma brucei heat shock protein, putative 0.0026 0.0027 0.0294
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0011 0.0035
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0189 0.2519
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0189 0.2083
Schistosoma mansoni hypothetical protein 0.0301 0.0869 0.0937
Loa Loa (eye worm) hypothetical protein 0.0255 0.0729 0.0782
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0083 0.02 0.0216
Loa Loa (eye worm) hypothetical protein 0.0299 0.0863 0.0925
Brugia malayi hypothetical protein 0.0096 0.0241 0.026
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.047 0.1387 0.149
Trypanosoma cruzi glycerol uptake protein, putative 0.0263 0.0751 0.8267
Brugia malayi hypothetical protein 0.0255 0.0729 0.0786
Brugia malayi hypothetical protein 0.0044 0.0081 0.0087
Onchocerca volvulus 0.0095 0.0238 0.0767
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0025 0.0023 0.0039
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.02 0.02
Trichomonas vaginalis D-aminoacylase, putative 0.0299 0.0863 0.2885
Mycobacterium tuberculosis Probable aminotransferase 0.0151 0.0411 0.0708
Brugia malayi hypothetical protein 0.0044 0.0081 0.0087
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0022 0.0013 0.0014
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0023 0.0075
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.02 0.0216
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0043 0.0078 0.0593
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0059 0.0196
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0067
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0009 0.0005
Echinococcus multilocularis lamin dm0 0.0026 0.0028 0.0028
Leishmania major hypothetical protein, conserved 0.0299 0.0863 0.654
Schistosoma mansoni patched 1 0.0034 0.0051 0.0054
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0043 0.0078 0.0861
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0083 0.02 0.064
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0025 0.0023 0.0025
Onchocerca volvulus 0.0241 0.0686 0.227
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.02 0.02
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0083 0.02 0.0216
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0058 0.0193
Echinococcus multilocularis ecdysone induced protein 78C 0.0083 0.02 0.02
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0287 0.3162
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0083 0.02 0.0211
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0066 0.0066
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.002 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0028 0.0025
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0016 0.0017
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0009 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0083 0.02 0.0211
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0009 0.001
Trypanosoma brucei glycerol uptake protein, putative 0.0263 0.0751 0.8267
Loa Loa (eye worm) G protein alpha subunit 3 0.002 0.0009 0.0005
Echinococcus multilocularis tumor protein p63 0.1384 0.4187 0.4187
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.004 0.0441
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0299 0.0863 0.1488
Schistosoma mansoni hypothetical protein 0.0033 0.0047 0.005
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Echinococcus multilocularis beta LACTamase domain containing family member 0.0299 0.0863 0.0863
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0009 0.0103
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0016 0.0171
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0003
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0016 0.0017
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0139 0.015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0029 0.0096
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0402 0.4427
Plasmodium falciparum heat shock protein 90 0.0026 0.0027 0.0356
Echinococcus granulosus o acyltransferase membrane bound domain 0.0263 0.0751 0.081
Loa Loa (eye worm) hypothetical protein 0.0044 0.0081 0.0082
Mycobacterium tuberculosis Probable oxidoreductase 0.0126 0.0333 0.0575
Brugia malayi cytochrome P450 0.0043 0.0078 0.0084
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.047 0.1387 0.1494
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.0131 0.0141
Loa Loa (eye worm) CYP4Cod1 0.0062 0.0138 0.0144
Loa Loa (eye worm) glutathione reductase 0.005 0.0099 0.0102
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0021 0.0011 0.0806
Trypanosoma cruzi glycerol uptake protein, putative 0.0263 0.0751 0.8267
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0145 0.039 0.0421
Echinococcus multilocularis mitogen activated protein kinase 0.0111 0.0287 0.0287
Giardia lamblia Heat shock protein HSP 90-alpha 0.0026 0.0027 0.0474
Schistosoma mansoni bromodomain containing protein 0.0019 0.0005 0.0005
Brugia malayi latrophilin 2 splice variant baaae 0.0104 0.0267 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0029 0.0096
Echinococcus granulosus dnaJ subfamily B 0.127 0.3836 0.4134
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0201 0.0563 0.0607
Mycobacterium tuberculosis Probable esterase LipL 0.0299 0.0863 0.1488
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0025 0.0023 0.0023
Echinococcus granulosus neuropeptide receptor A26 0.1008 0.3035 0.3271
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0139 0.0145
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0009 0.001
Brugia malayi beta-lactamase family protein 0.0299 0.0863 0.093
Brugia malayi hypothetical protein 0.0501 0.1482 0.1597
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0025 0.0023 0.025
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0056 0.0056
Schistosoma mansoni transcription factor LCR-F1 0.0301 0.0869 0.0937
Leishmania major heat shock protein 83-1 0.0026 0.0027 0.0203
Trypanosoma cruzi cytochrome P450, putative 0.0062 0.0138 0.152
Brugia malayi nuclear receptor RXR 0.0039 0.0066 0.0072
Schistosoma mansoni endoplasmin 0.0026 0.0027 0.0029
Echinococcus multilocularis thyroid hormone receptor alpha 0.0083 0.02 0.02
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0043 0.0078 0.0135
Echinococcus granulosus Protein patched homolog 1 0.0034 0.0051 0.0054
Trypanosoma brucei heat shock protein, putative 0.0026 0.0027 0.0294
Brugia malayi nuclear hormone receptor 0.0039 0.0066 0.0072
Mycobacterium ulcerans aldehyde dehydrogenase 0.0448 0.1319 1
Mycobacterium ulcerans hypothetical protein 0.0151 0.0411 0.3113
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.0128
Loa Loa (eye worm) hypothetical protein 0.0041 0.0074 0.0075
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.0131 0.1441
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0025 0.0023 0.0173
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0027 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0029 0.0096
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0263 0.0751 0.081
Trypanosoma brucei heat shock protein, putative 0.0026 0.0027 0.0294
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0025 0.0023 0.002
Echinococcus granulosus Aminotransferase class III 0.0022 0.0013 0.0014
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0011 0.0007
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.0131 0.0141
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0059 0.0196
Trichomonas vaginalis set domain proteins, putative 0.0994 0.299 1
Schistosoma mansoni hypothetical protein 0.0025 0.0023 0.0025
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0083 0.02 0.02
Giardia lamblia Heat shock protein HSP 90-alpha 0.0021 0.0011 0.0187
Echinococcus granulosus lysosomal alpha glucosidase 0.0164 0.0449 0.0484

Activities

Activity type Activity value Assay description Source Reference
Kd (binding) = 88 uM In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes. ChEMBL. 10956209
Kd (binding) = 94 uM In vitro affinity at wild type Dopamine receptor D2 on C6 (glioma) cell membranes. ChEMBL. 10956209
Kd (binding) = 225 uM In vitro affinity at mutant D2 receptor (S197A) in C6 (glioma) cell membranes. ChEMBL. 10956209
Kd (binding) = 251 uM In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes. ChEMBL. 10956209

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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