Detailed information for compound 257538

Basic information

Technical information
  • TDR Targets ID: 257538
  • Name: N-(4-chloro-2-fluorophenyl)-6,7-bis(2-methoxy ethoxy)quinazolin-4-amine
  • MW: 421.85 | Formula: C20H21ClFN3O4
  • H donors: 1 H acceptors: 2 LogP: 3.79 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCCOc1cc2c(ncnc2cc1OCCOC)Nc1ccc(cc1F)Cl
  • InChi: 1S/C20H21ClFN3O4/c1-26-5-7-28-18-10-14-17(11-19(18)29-8-6-27-2)23-12-24-20(14)25-16-4-3-13(21)9-15(16)22/h3-4,9-12H,5-8H2,1-2H3,(H,23,24,25)
  • InChiKey: XTELADPHRDQWCD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(4-chloro-2-fluoro-phenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
  • N-(4-chloro-2-fluorophenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
  • [6,7-bis(2-methoxyethoxy)quinazolin-4-yl]-(4-chloro-2-fluoro-phenyl)amine
  • Anilinoquinazoline deriv. 14

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens kinase insert domain receptor Starlite/ChEMBL References
Homo sapiens fms-related tyrosine kinase 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Onchocerca volvulus Get druggable targets OG5_130320 All targets in OG5_130320
Onchocerca volvulus Tyrosine kinase homolog Get druggable targets OG5_130320 All targets in OG5_130320
Loa Loa (eye worm) TK/KIN16 protein kinase Get druggable targets OG5_130320 All targets in OG5_130320
Brugia malayi Immunoglobulin I-set domain containing protein Get druggable targets OG5_130320 All targets in OG5_130320
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0038 0.0013 0.0297
Echinococcus granulosus serine:threonine protein kinase 0.0085 0.026 0.026
Trichomonas vaginalis AGC family protein kinase 0.014 0.0549 0.2284
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0039 0.0019 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Brugia malayi Guanylyl cyclase protein 23 0.0046 0.0057 0.006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0041 0.0029 0.0031
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0122 0.0455 0.0988
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0101 0.0346 0.3632
Schistosoma mansoni hypothetical protein 0.0041 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0076 0.0217 0.023
Trichomonas vaginalis AGC family protein kinase 0.0108 0.0382 0.1589
Trichomonas vaginalis CK1 family protein kinase 0.008 0.0239 0.0992
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0046 0.0057 0.0123
Echinococcus granulosus neuroglian 0.0098 0.0332 0.0332
Echinococcus multilocularis dual specificity 0.0103 0.0357 0.0775
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0382 0.043
Brugia malayi SH2 domain containing protein 0.0181 0.0767 0.0815
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.1083 0.1219
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0193 0.083 0.1803
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Brugia malayi Protein kinase domain containing protein 0.0062 0.0139 0.0148
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0057 0.0362
Onchocerca volvulus 0.0058 0.0118 0.0138
Echinococcus granulosus serine threonine protein kinase nrc 0.0116 0.0426 0.0426
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0057 0.0362
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.004 0.0023 0.0096
Giardia lamblia Kinase, CAMK CAMKL 0.0066 0.0163 0.1762
Onchocerca volvulus 0.0036 0.0004 0.0005
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.006
Echinococcus granulosus twitchin 0.0207 0.0906 0.0906
Loa Loa (eye worm) hypothetical protein 0.0106 0.0372 0.0395
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.1352 0.1523
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0046 0.0057 0.0057
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0062 0.0139 0.1599
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.0141 0.1627
Schistosoma mansoni serine/threonine-protein kinase 0.0123 0.046 0.0519
Schistosoma mansoni suppressor of cytokine signaling 0.0039 0.0019 0.0021
Onchocerca volvulus 0.0106 0.0372 0.0432
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0196 0.0845 0.0898
Schistosoma mansoni septate junction protein 0.0076 0.0217 0.0244
Echinococcus multilocularis roundabout 2 0.0245 0.1106 0.2404
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0083 0.0251 0.0545
Onchocerca volvulus 0.0137 0.0535 0.0621
Brugia malayi Fibronectin type III domain containing protein 0.0169 0.0704 0.0749
Echinococcus granulosus tyrosine protein kinase Fyn 0.018 0.0763 0.0763
Onchocerca volvulus 0.0174 0.0731 0.085
Schistosoma mansoni protein kinase 0.0074 0.0205 0.0231
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0057 0.006
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0193 0.083 0.083
Schistosoma mansoni hypothetical protein 0.0036 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0041 0.0028 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0341 0.0384
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Loa Loa (eye worm) DOMON domain-containing protein 0.0174 0.0731 0.0777
Entamoeba histolytica protein kinase domain containing protein 0.0074 0.0205 0.1517
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0058 0.0118 0.0126
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0107 0.038 0.0825
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0082 0.0245 0.0245
Echinococcus multilocularis nervana 2 0.0092 0.0297 0.0646
Echinococcus multilocularis tyrosine protein kinase csk 0.0046 0.0057 0.0123
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0046 0.0057 0.006
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0141 0.0588
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0037 0.0011 0.0024
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0085 0.0264 0.0264
Loa Loa (eye worm) hypothetical protein 0.0058 0.0118 0.0126
Echinococcus multilocularis lachesin 0.0076 0.0217 0.0471
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0108 0.0382 0.0382
Loa Loa (eye worm) CMGC/MAPK/NMO protein kinase 0.0136 0.0529 0.0562
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0261 0.119 0.1382
Schistosoma mansoni tyrosine kinase 0.0366 0.174 0.1959
Brugia malayi Temporarily assigned gene name protein 59 0.0083 0.0251 0.0266
Echinococcus granulosus myotubularin protein 13 0.0038 0.0013 0.0013
Echinococcus multilocularis dual specificity 0.0103 0.0357 0.0775
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.007 0.0185 0.1875
Toxoplasma gondii AGC kinase 0.0216 0.0952 1
Schistosoma mansoni protein kinase 0.0046 0.0057 0.0064
Echinococcus multilocularis CDC7 cell division cycle 7 0.0066 0.0165 0.0358
Brugia malayi Immunoglobulin domain containing protein 0.0041 0.0028 0.003
Echinococcus granulosus dual specificity 0.0103 0.0357 0.0357
Echinococcus granulosus titin 0.0036 0.0003 0.0003
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0141 0.0141
Loa Loa (eye worm) TK protein kinase 0.0229 0.1018 0.1082
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0046 0.0057 0.006
Brugia malayi Protein kinase domain containing protein 0.0143 0.0567 0.0602
Entamoeba histolytica cell division protein kinase 2, putative 0.0088 0.0278 0.2084
Echinococcus multilocularis serine:threonine protein kinase N2 0.022 0.0975 0.2119
Schistosoma mansoni protein kinase C mu 0.0161 0.0663 0.0747
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0046 0.0057 0.006
Echinococcus granulosus titin 0.0036 0.0003 0.0003
Onchocerca volvulus 0.0082 0.0247 0.0287
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0038 0.0013 0.0297
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Echinococcus granulosus SH2 motif 0.0039 0.0019 0.0019
Entamoeba histolytica protein kinase, putative 0.0216 0.0952 0.7319
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0357 0.1483
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0165 0.0681 0.0724
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0046 0.0057 0.006
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0013 0.0014
Onchocerca volvulus 0.0174 0.0731 0.085
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0074 0.0205 0.4822
Trichomonas vaginalis AGC family protein kinase 0.0223 0.0987 0.4102
Brugia malayi bone morphogenetic protein type 1 receptor 0.0046 0.0057 0.006
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0869 0.3611
Echinococcus multilocularis tyrosine protein kinase Src64B 0.018 0.0763 0.1659
Echinococcus granulosus Glutaredoxin protein 5 0.0092 0.0297 0.0297
Echinococcus multilocularis insulin receptor 0.0366 0.174 0.378
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Echinococcus multilocularis c src tyrosine kinase 0.0115 0.042 0.0914
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0056 0.011 0.1267
Schistosoma mansoni hypothetical protein 0.0083 0.0251 0.0282
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0118 0.0435 0.0463
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0107 0.0379 0.0824
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.006 0.0133 0.0133
Brugia malayi Uncoordinated protein 44 0.0037 0.0011 0.0012
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0063 0.0147 0.1065
Echinococcus multilocularis aurora kinase A 0.0108 0.0382 0.083
Leishmania major protein kinase, putative 0.0114 0.0414 0.4765
Giardia lamblia Kinase, CK1 Casein kinase 0.008 0.0239 0.2639
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0107 0.0379 0.0379
Plasmodium falciparum tyrosine kinase-like protein, putative 0.006 0.0131 0.286
Onchocerca volvulus 0.0058 0.0118 0.0138
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0083 0.0251 0.0251
Schistosoma mansoni ankyrin 23/unc44 0.0037 0.0011 0.0012
Brugia malayi Disorganized muscle protein 1 0.0036 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0057 0.0235
Entamoeba histolytica protein kinase, putative 0.0091 0.0292 0.2188
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0046 0.0057 0.0594
Schistosoma mansoni tyrosine kinase 0.0301 0.1399 0.1576
Echinococcus granulosus protein kinase 0.0113 0.0412 0.0412
Toxoplasma gondii STE kinase 0.0046 0.0057 0.0594
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Loa Loa (eye worm) hypothetical protein 0.0909 0.4602 0.4891
Schistosoma mansoni serine/threonine protein kinase 0.0353 0.1675 0.1886
Echinococcus granulosus protein kinase C gamma type 0.0155 0.0629 0.0629
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0057 0.006
Onchocerca volvulus 0.0056 0.011 0.0128
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0147 0.0589 0.0664
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.0141 0.1627
Brugia malayi DOMON domain containing protein 0.0174 0.0731 0.0777
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Brugia malayi Protein kinase domain containing protein 0.0425 0.2054 0.2183
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0003 0.0003
Schistosoma mansoni dopamine-beta-monooxygenase 0.1722 0.8879 1
Schistosoma mansoni tyrosine kinase 0.018 0.0763 0.086
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0039 0.0019 0.004
Loa Loa (eye worm) hypothetical protein 0.0076 0.0217 0.023
Trichomonas vaginalis STE family protein kinase 0.0064 0.015 0.0625
Schistosoma mansoni protein kinase 0.0321 0.1507 0.1697
Loa Loa (eye worm) hypothetical protein 0.0041 0.0028 0.003
Schistosoma mansoni cell adhesion molecule 0.0098 0.0332 0.0374
Brugia malayi Doublecortin family protein 0.0112 0.0403 0.0428
Toxoplasma gondii histone kinase SNF1, putative 0.0066 0.0163 0.1717
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0107 0.038 0.038
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Echinococcus multilocularis peroxidasin 0.0077 0.0218 0.0473
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0046 0.0057 0.0064
Schistosoma mansoni protein kinase 0.0143 0.0567 0.0638
Echinococcus granulosus casein kinase i 0.008 0.0239 0.0239
Entamoeba histolytica protein kinase, putative 0.0124 0.047 0.3572
Echinococcus multilocularis tyrosine protein kinase Fyn 0.018 0.0763 0.1659
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0114 0.0414 0.4195
Entamoeba histolytica hypothetical protein 0.0091 0.0292 0.2188
Echinococcus granulosus low density lipoprotein receptor ldl 0.0041 0.0028 0.0028
Trichomonas vaginalis AGC family protein kinase 0.006 0.0133 0.0551
Toxoplasma gondii NEK kinase 0.0038 0.0013 0.0133
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Loa Loa (eye worm) hypothetical protein 0.0076 0.0217 0.023
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0321 0.1507 0.1507
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.02 0.0869 0.1888
Echinococcus granulosus jumonji domain containing protein 0.004 0.0023 0.0023
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0084 0.0256 0.0272
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0013 0.0053
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0064 0.015 0.015
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0095 0.0317 0.0336
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0038 0.0013 0.0128
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0357 0.1483
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.007 0.0185 0.213
Loa Loa (eye worm) hypothetical protein 0.0089 0.0285 0.0303
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0084 0.0256 0.2942
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.0792 0.0892
Echinococcus multilocularis epidermal growth factor receptor 0.0347 0.1641 0.3566
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0122 0.0455 0.0483
Trypanosoma cruzi casein kinase, putative 0.008 0.0239 0.2746
Echinococcus multilocularis twitchin 0.006 0.0132 0.0286
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0357 0.1483
Loa Loa (eye worm) hypothetical protein 0.0077 0.0218 0.0231
Loa Loa (eye worm) hypothetical protein 0.0147 0.0589 0.0626
Echinococcus granulosus tyrosine protein kinase ABL1 0.0238 0.1069 0.1069
Brugia malayi Protein kinase domain containing protein 0.014 0.0549 0.0584
Echinococcus multilocularis neuroglian 0.0098 0.0332 0.0721
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0046 0.0057 0.0594
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.0165 0.0685
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0909 0.4602 0.4891
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0013 0.0053
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0003 0.0003
Toxoplasma gondii casein kinase I 0.008 0.0239 0.2506
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0075 0.0208 0.0208
Echinococcus granulosus roundabout 2 0.0098 0.0332 0.0332
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0098 0.0332 0.0721
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0731 0.0824
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0063 0.0145 0.1669
Echinococcus multilocularis SH2 domain containing protein 7 0.0039 0.0019 0.004
Entamoeba histolytica tyrosin kinase, putative 0.0046 0.0057 0.0362
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Leishmania major protein kinase A catalytic subunit isoform 2 0.0084 0.0256 0.2942
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Echinococcus multilocularis 0.0089 0.0285 0.062
Echinococcus granulosus tyrosine protein kinase Blk 0.015 0.0603 0.0603
Echinococcus multilocularis dual specificity 0.0103 0.0357 0.0775
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0076 0.0217 0.0244
Brugia malayi Tyrosine-protein kinase PR2 0.0046 0.0057 0.006
Schistosoma mansoni myosin-binding protein-related 0.0058 0.0118 0.0133
Echinococcus granulosus protein kinase 0.0046 0.0057 0.0057
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0057 0.0362
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Entamoeba histolytica serine/threonine protein kinase, putative 0.0066 0.0163 0.1193
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0036 0.0003 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.0165 0.0685
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0088 0.0278 0.0278
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Schistosoma mansoni protein kinase 0.007 0.0185 0.0208
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0057 0.0362
Leishmania major protein kinase, putative 0.007 0.0185 0.213
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Brugia malayi map kinase activated protein kinase protein 2 0.0292 0.1352 0.1437
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0123 0.046 0.53
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0108 0.0382 0.8979
Echinococcus granulosus hemicentin 1 0.0076 0.0217 0.0217
Brugia malayi hypothetical protein 0.0042 0.0035 0.0037
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0041 0.0028 0.0062
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0046 0.0057 0.006
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.02 0.0869 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.1614 0.1715
Entamoeba histolytica casein kinase, putative 0.008 0.0239 0.1776
Echinococcus granulosus serine:threonine protein kinase MARK2 0.016 0.0657 0.0657
Echinococcus multilocularis N chimaerin 0.007 0.0182 0.0395
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0041 0.0028 0.0028
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0098 0.0332 0.0374
Schistosoma mansoni nephrin 0.0205 0.0893 0.1005
Echinococcus multilocularis Immunoglobulin 0.0147 0.0589 0.128
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0036 0.0003 0.0004
Schistosoma mansoni titin 0.0036 0.0003 0.0004
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Schistosoma mansoni tyrosine kinase 0.0115 0.042 0.0474
Echinococcus granulosus serine:threonine kinase SAD 1 0.0066 0.0163 0.0163
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0046 0.0057 0.0057
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0039 0.0019 0.004
Trichomonas vaginalis AGC family protein kinase 0.0108 0.0382 0.1589
Brugia malayi Protein kinase domain containing protein 0.0085 0.026 0.0277
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Trypanosoma cruzi casein kinase, putative 0.008 0.0239 0.2746
Onchocerca volvulus 0.0036 0.0003 0.0004
Brugia malayi Protein kinase domain containing protein 0.0444 0.2154 0.229
Brugia malayi hypothetical protein 0.0169 0.0704 0.0749
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0076 0.0217 0.0471
Toxoplasma gondii AGC kinase 0.0084 0.0256 0.2685
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0046 0.0057 0.0064
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0039 0.0019 0.0019
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0118 0.0126
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus granulosus aurora kinase A 0.0108 0.0382 0.0382
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0039 0.0019 0.0022
Entamoeba histolytica protein kinase domain containing protein 0.0095 0.0317 0.2383
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0057 0.006
Onchocerca volvulus 0.0216 0.0954 0.1108
Giardia lamblia Kinase, CMGC SRPK 0.0062 0.0139 0.1475
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0074 0.0205 0.0218
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Entamoeba histolytica protein kinase, putative 0.0108 0.0382 0.2892
Schistosoma mansoni tyrosine kinase 0.0301 0.1399 0.1576
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.0141 0.1627
Brugia malayi basement membrane proteoglycan 0.0041 0.0028 0.003
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0084 0.0256 0.2942
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0066 0.0163 0.1882
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0057 0.006
Loa Loa (eye worm) hypothetical protein 0.0041 0.0028 0.003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0869 0.3611
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0103 0.0357 0.0379
Brugia malayi casein kinase I 0.008 0.0239 0.0254
Brugia malayi Serine/threonine-protein kinase SULU 0.0165 0.0681 0.0724
Echinococcus multilocularis mitogen activated protein kinase 14 0.0118 0.0435 0.0946
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0046 0.0057 0.006
Schistosoma mansoni protein tyrosine kinase 0.0046 0.0057 0.0064
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0088 0.0278 0.0296
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0057 0.006
Trichomonas vaginalis STE family protein kinase 0.0046 0.0057 0.0235
Onchocerca volvulus 0.0083 0.0251 0.0291
Giardia lamblia Kinase, PLK 0.02 0.0869 1
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.019 0.0816 0.0868
Brugia malayi integrin-linked kinase 0.0046 0.0057 0.006
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0057 0.0362
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.047 0.0529
Brugia malayi Heparan sulfate 0.0041 0.0028 0.003
Brugia malayi Variant SH3 domain containing protein 0.0046 0.0058 0.0062
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0085 0.026 0.1944
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Schistosoma mansoni kinase 0.0214 0.0941 0.1059
Echinococcus multilocularis hemicentin 1 0.0076 0.0217 0.0471
Loa Loa (eye worm) AUR protein kinase 0.0108 0.0382 0.0406
Echinococcus multilocularis down syndrome cell adhesion 0.0036 0.0003 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.01 0.034 0.0383
Giardia lamblia Kinase, CMGC GSK 0.0095 0.0317 0.355
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0066 0.0163 0.1657
Onchocerca volvulus Putative titin 0.0036 0.0003 0.0004
Echinococcus granulosus tensin 0.0039 0.0019 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0165 0.0186
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0052 0.0091 0.0198
Brugia malayi Tyrosine-protein kinase abl-1 0.0095 0.0314 0.0334
Trichomonas vaginalis CMGC family protein kinase 0.0088 0.0278 0.1156
Echinococcus granulosus serine:threonine protein kinase PLK1 0.02 0.0869 0.0869
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0057 0.006
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Trichomonas vaginalis AGC family protein kinase 0.006 0.0133 0.0551
Leishmania major protein kinase, putative 0.0038 0.0013 0.0145
Trichomonas vaginalis TKL family protein kinase 0.0047 0.0061 0.0254
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0057 0.006
Brugia malayi Death domain containing protein 0.0037 0.0011 0.0012
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0909 0.4602 0.4602
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0091 0.0292 0.3356
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0124 0.047 0.047
Schistosoma mansoni vav2 0.0076 0.0216 0.0244
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus granulosus contactin 0.0098 0.0332 0.0332
Plasmodium falciparum calcium-dependent protein kinase 2 0.0075 0.0208 0.4733
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0057 0.0362
Echinococcus granulosus tyrosine protein kinase csk 0.0046 0.0057 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0057 0.0362
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0121 0.0453 0.0482
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Echinococcus granulosus NDR protein kinase 0.0124 0.047 0.047
Loa Loa (eye worm) hypothetical protein 0.0178 0.075 0.0797
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0066 0.0163 0.1882
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Echinococcus multilocularis protein kinase shaggy 0.0095 0.0317 0.0688
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0113 0.0412 0.0438
Brugia malayi Immunoglobulin I-set domain containing protein 0.0076 0.0217 0.023
Onchocerca volvulus 0.0085 0.026 0.0302
Onchocerca volvulus 0.0036 0.0003 0.0004
Brugia malayi Protein kinase domain containing protein 0.0085 0.026 0.0276
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0114 0.0414 0.4765
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0066 0.0163 0.0355
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus multilocularis tyrosine protein kinase shark 0.0243 0.1093 0.2376
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0185 0.0791 0.1719
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0444 0.2154 0.229
Trypanosoma brucei Flagellum attachment zone protein 20 0.0046 0.0057 0.0573
Echinococcus multilocularis PAK box P21 Rho binding 0.0048 0.0066 0.0143
Brugia malayi Prion-like- 0.0076 0.0217 0.023
Echinococcus multilocularis roundabout 2 0.0098 0.0332 0.0721
Echinococcus granulosus tyrosine kinase 0.015 0.0603 0.0603
Echinococcus multilocularis Glutaredoxin protein 5 0.0092 0.0297 0.0646
Brugia malayi Stress-activated protein kinase jnk-1 0.0196 0.0845 0.0898
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0064 0.015 0.0326
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Giardia lamblia Kinase, CMGC CDK 0.0088 0.0278 0.3101
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Trichomonas vaginalis CAMK family protein kinase 0.0085 0.026 0.108
Schistosoma mansoni vam6/vps39 related 0.0083 0.0251 0.0282
Brugia malayi Protein kinase domain containing protein 0.0144 0.057 0.0606
Loa Loa (eye worm) projectin 0.0058 0.0118 0.0126
Trichomonas vaginalis CK1 family protein kinase 0.008 0.0239 0.0992
Schistosoma mansoni titin 0.0076 0.0217 0.0244
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0037
Schistosoma mansoni basigin related 0.0041 0.0028 0.0032
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.006 0.0133 0.0141
Schistosoma mansoni protein kinase 0.0113 0.0412 0.0464
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0278 0.0313
Brugia malayi Raf kinase 0.0046 0.0057 0.006
Plasmodium falciparum casein kinase 2, alpha subunit 0.0074 0.0205 0.4664
Echinococcus multilocularis receptor type guanylyl cyclase 0.0046 0.0057 0.0123
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0414 0.1721
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0138 0.0539 0.0573
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0046 0.0057 0.0235
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0059 0.0127 0.0276
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0088 0.0278 0.0296
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Schistosoma mansoni vesicular amine transporter 0.0147 0.0589 0.0664
Echinococcus granulosus ephrin type A receptor 4 A 0.0093 0.0306 0.0306
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Loa Loa (eye worm) SH2 domain-containing protein 0.0039 0.0019 0.002
Loa Loa (eye worm) LAD-2 short isoform 0.0041 0.0028 0.003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0003 0.0003
Leishmania major protein kinase A catalytic subunit 0.0084 0.0256 0.2942
Echinococcus multilocularis dual specificity protein kinase clk2 0.0114 0.0414 0.0899
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0657 0.074
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0136 0.0529 0.115
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0095 0.0317 0.0357
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0193 0.083 0.1803
Echinococcus granulosus basement membrane specific heparan sulfate 0.0041 0.0028 0.0028
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0063 0.0145 0.1049
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Entamoeba histolytica hypothetical protein 0.0046 0.0057 0.0362
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0046 0.0057 0.0064
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0039 0.0019 0.004
Echinococcus granulosus calcium dependent protein kinase 0.005 0.008 0.008
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0057 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0661 0.2747
Echinococcus granulosus tyrosine protein kinase Src42A 0.0105 0.0369 0.0369
Loa Loa (eye worm) hypothetical protein 0.0039 0.0019 0.002
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0039 0.0019 0.0021
Echinococcus granulosus nervana 2 0.0092 0.0297 0.0297
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0112 0.0403 0.0428
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0057 0.006
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Trichomonas vaginalis AGC family protein kinase 0.014 0.0549 0.2284
Echinococcus granulosus nuclear factor of activated T cells 5 0.0081 0.0242 0.0242
Echinococcus granulosus tyrosine protein kinase HCK 0.0111 0.04 0.04
Echinococcus multilocularis neuroglian 0.0183 0.0777 0.1689
Loa Loa (eye worm) hypothetical protein 0.0172 0.0719 0.0764
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0075 0.0208 0.2186
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0076 0.0217 0.023
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0037 0.0011 0.0011
Entamoeba histolytica cysteine surface protein, putative 0.0046 0.0057 0.0362
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0046 0.0057 0.0057
Loa Loa (eye worm) STAT protein 0.0039 0.0019 0.002
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.026 0.0277
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0066 0.0163 0.3841
Plasmodium falciparum calcium-dependent protein kinase 5 0.0075 0.0208 0.4733
Echinococcus multilocularis rac serine:threonine kinase 0.0123 0.046 0.1001
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0069 0.0179 0.019
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0069 0.0179 0.019
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Echinococcus multilocularis 0.015 0.0604 0.1313
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0261 0.119 0.1264
Giardia lamblia Kinase, CAMK CAMKL 0.0066 0.0163 0.1762
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0116 0.0426 1
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Loa Loa (eye worm) AUR protein kinase 0.0108 0.0382 0.0406
Onchocerca volvulus 0.0143 0.057 0.0662
Echinococcus granulosus signal transduction protein lnk realted 0.0039 0.0019 0.0019
Brugia malayi hypothetical protein 0.0046 0.0057 0.006
Loa Loa (eye worm) hypothetical protein 0.0169 0.0704 0.0749
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0041 0.0028 0.0032
Schistosoma mansoni tyrosine kinase 0.0421 0.203 0.2286
Loa Loa (eye worm) AGC/AKT protein kinase 0.0223 0.0987 0.1049
Schistosoma mansoni hemicentin 0.0058 0.0118 0.0133
Brugia malayi SH2 domain containing protein 0.0039 0.0019 0.002
Trypanosoma cruzi casein kinase, putative 0.008 0.0239 0.2746
Loa Loa (eye worm) hypothetical protein 0.0066 0.0163 0.0173
Loa Loa (eye worm) hypothetical protein 0.0105 0.0366 0.0389
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0272 0.1245 0.1245
Trichomonas vaginalis AGC family protein kinase 0.0223 0.0987 0.4102
Brugia malayi DOMON domain containing protein 0.0174 0.0731 0.0777
Loa Loa (eye worm) CDC7 protein kinase 0.0066 0.0165 0.0175
Trichomonas vaginalis CMGC family protein kinase 0.0095 0.0317 0.1316
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Onchocerca volvulus 0.0241 0.1083 0.1257
Echinococcus multilocularis casein kinase I alpha 0.008 0.0239 0.0518
Mycobacterium leprae conserved hypothetical protein 0.0035 0 0.5
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0058 0.0118 0.0118
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0188 0.0803 0.0803
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0357 0.1483
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0046 0.0057 0.0064
Echinococcus granulosus tyrosine protein kinase Srms 0.0387 0.185 0.185
Echinococcus granulosus tyrosine protein kinase Fyn 0.018 0.0763 0.0763
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0064 0.015 0.0326
Loa Loa (eye worm) hypothetical protein 0.0137 0.0535 0.0568
Trichomonas vaginalis STE family protein kinase 0.0064 0.015 0.0625
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus granulosus expressed conserved protein 0.0039 0.0019 0.0019
Brugia malayi p70 ribosomal S6 kinase beta 0.0216 0.0952 0.1012
Onchocerca volvulus 0.0036 0.0003 0.0004
Brugia malayi Prion-like- 0.0036 0.0003 0.0003
Brugia malayi Furin-like cysteine rich region family protein 0.0533 0.2621 0.2786
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Echinococcus multilocularis cyclin dependent kinase 1 0.0088 0.0278 0.0604
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0075 0.0208 0.0452
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Entamoeba histolytica hypothetical protein 0.0046 0.0057 0.0362
Schistosoma mansoni protein kinase 0.0196 0.0848 0.0955
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.004 0.0028 0.0116
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0272 0.1245 0.1323
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0292 0.1352 0.2938
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0055 0.0103 0.0109
Loa Loa (eye worm) TK protein kinase 0.0046 0.0057 0.006
Brugia malayi Protein kinase domain containing protein 0.0366 0.174 0.1849
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Loa Loa (eye worm) hypothetical protein 0.0169 0.0704 0.0749
Echinococcus granulosus casein kinase I delta 0.008 0.0239 0.0239
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.018 0.0763 0.0763
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0313 0.1461 0.1461
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0038 0.0013 0.0145
Schistosoma mansoni protein kinase 0.008 0.0239 0.0269
Loa Loa (eye worm) TK protein kinase 0.0046 0.0057 0.006
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0039 0.0019 0.0019
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0038 0.0013 0.0145
Echinococcus granulosus growth factor receptor bound protein 2 0.0071 0.0187 0.0187
Trypanosoma cruzi Protein kinase B 0.0123 0.046 0.53
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0172 0.0719 0.0719
Loa Loa (eye worm) hypothetical protein 0.0075 0.0212 0.0225
Onchocerca volvulus 0.0039 0.0019 0.0022
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Echinococcus multilocularis tyrosine protein kinase csk 0.0046 0.0057 0.0123
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.007 0.0182 0.0182
Trypanosoma brucei rac serine-threonine kinase, putative 0.0223 0.0987 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.006
Loa Loa (eye worm) hypothetical protein 0.0098 0.0332 0.0353
Echinococcus granulosus serine:threonine protein kinase MARK2 0.016 0.0657 0.0657
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.004 0.0023 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0239 0.0269
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0046 0.0057 0.006
Giardia lamblia Kinase, NEK 0.0101 0.0346 0.3891
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0062 0.0144 0.0153
Echinococcus multilocularis calcium dependent protein kinase 0.005 0.008 0.0173
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0046 0.0058 0.0062
Echinococcus multilocularis casein kinase I delta 0.008 0.0239 0.0518
Loa Loa (eye worm) hypothetical protein 0.0444 0.2154 0.229
Entamoeba histolytica cell division protein kinase 2, putative 0.0088 0.0278 0.2084
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Onchocerca volvulus 0.0056 0.0112 0.013
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0095 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.0037
Echinococcus granulosus serine:threonine protein kinase N2 0.022 0.0975 0.0975
Loa Loa (eye worm) hypothetical protein 0.0085 0.026 0.0277
Plasmodium falciparum serine/threonine protein kinase, putative 0.0108 0.0382 0.8948
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0064 0.015 0.0326
Schistosoma mansoni protein kinase 0.0185 0.0791 0.0891
Entamoeba histolytica protein kinase, putative 0.0054 0.0101 0.0704
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0047 0.0064 0.0064
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0357 0.1483
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0046 0.0057 0.006
Brugia malayi serine/threonine-protein kinase PAK 7 0.0172 0.072 0.0765
Echinococcus multilocularis casein kinase I gamma 0.0158 0.0646 0.1404
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus granulosus dual specificity 0.0103 0.0357 0.0357
Brugia malayi Protein kinase domain containing protein 0.0062 0.0139 0.0148
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0039 0.0019 0.004
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0306 0.0306
Echinococcus multilocularis tyrosine protein kinase 0.0224 0.0991 0.2154
Echinococcus multilocularis SH2 motif 0.0039 0.0019 0.004
Onchocerca volvulus 0.0039 0.0019 0.0022
Echinococcus multilocularis Immunoglobulin 0.0147 0.0589 0.128
Schistosoma mansoni adapter molecule crk 0.0069 0.0179 0.0201
Plasmodium vivax serine/threonine protein kinase, putative 0.0062 0.0139 0.3264
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0046 0.0057 0.0235
Onchocerca volvulus 0.0066 0.0165 0.0192
Plasmodium falciparum tyrosine kinase-like protein 0.0046 0.0057 0.1063
Brugia malayi DOMON domain containing protein 0.0174 0.0731 0.0777
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0041 0.0028 0.0062
Brugia malayi SH2 domain containing protein 0.0085 0.026 0.0277
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0114 0.0414 0.4765
Echinococcus granulosus casein kinase I alpha 0.008 0.0239 0.0239
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0103 0.0357 0.4107
Brugia malayi Immunoglobulin I-set domain containing protein 0.0047 0.0064 0.0068
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0141 0.1627
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Brugia malayi Immunoglobulin I-set domain containing protein 0.1823 0.9409 1
Echinococcus granulosus tyrosine protein kinase csk 0.0046 0.0057 0.0057
Echinococcus granulosus titin 0.0082 0.0247 0.0247
Entamoeba histolytica protein kinase 2, putative 0.0116 0.0426 0.323
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0088 0.0278 0.3201
Loa Loa (eye worm) protein kinase domain-containing protein 0.0046 0.0057 0.006
Schistosoma mansoni serine/threonine-protein kinase 0.0123 0.046 0.0519
Plasmodium vivax protein kinase Crk2 0.0088 0.0278 0.6535
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0046 0.0057 0.006
Echinococcus granulosus casein kinase ii subunit alpha 0.0074 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0039 0.0019 0.002
Schistosoma mansoni cell adhesion molecule 0.0058 0.0118 0.0133
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0091 0.0292 0.3356
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Entamoeba histolytica protein kinase domain containing protein 0.007 0.0185 0.136
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0091 0.0292 0.2954
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0116 0.0426 0.0426
Trypanosoma cruzi NIMA-related kinase, putative 0.0038 0.0013 0.0145
Entamoeba histolytica tyrosin kinase, putative 0.0048 0.0069 0.0458
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0313 0.1461 0.3174
Schistosoma mansoni hypothetical protein 0.0036 0.0003 0.0004
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0247 0.1114 0.1184
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Brugia malayi follicle stimulating hormone receptor 0.0255 0.1157 0.123
Trichomonas vaginalis CMGC family protein kinase 0.0074 0.0205 0.0853
Brugia malayi Immunoglobulin I-set domain containing protein 0.0041 0.0028 0.003
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0047 0.0064 0.014
Entamoeba histolytica hypothetical protein, conserved 0.0046 0.0057 0.0362
Trichomonas vaginalis protein tyrosine kinase, putative 0.0046 0.0057 0.0235
Trypanosoma cruzi cdc2-related kinase 3 0.0088 0.0278 0.3201
Brugia malayi intracellular kinase 0.0095 0.0317 0.0336
Echinococcus multilocularis NCK adaptor protein 0.0071 0.0187 0.0405
Giardia lamblia Kinase, CMGC CLK 0.0114 0.0414 0.4688
Brugia malayi tRNA modification GTPase TrmE family protein 0.0039 0.0019 0.002
Brugia malayi Animal haem peroxidase family protein 0.0036 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Schistosoma mansoni suppressor of cytokine signaling 0.0039 0.0019 0.0021
Echinococcus multilocularis mitogen activated protein kinase 11 0.0118 0.0435 0.0946
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0038 0.0013 0.0145
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0041 0.0028 0.0062
Trypanosoma cruzi casein kinase, putative 0.008 0.0239 0.2746
Brugia malayi Protein kinase domain containing protein 0.0085 0.026 0.0277
Echinococcus granulosus mitogen activated protein kinase 14 0.0118 0.0435 0.0435
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0133 0.0149
Brugia malayi protein kinase C II. 0.0156 0.0638 0.0678
Plasmodium falciparum glycogen synthase kinase 3 0.0095 0.0317 0.736
Trypanosoma brucei protein kinase, putative 0.0062 0.0141 0.1433
Echinococcus multilocularis tyrosine protein kinase csk 0.0046 0.0057 0.0123
Brugia malayi hypothetical protein 0.0083 0.0251 0.0266
Schistosoma mansoni rap gtpase-activating protein 0.0083 0.0251 0.0282
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0098 0.0332 0.0721
Echinococcus granulosus natriuretic peptide receptor 1 0.0046 0.0057 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.0098 0.0332 0.0353
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Entamoeba histolytica p21-activated kinase 0.007 0.0185 0.1361
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0075 0.0208 0.0208
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0003 0.0003
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0075 0.0208 0.4889
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0605 0.0681
Echinococcus granulosus receptor type guanylyl cyclase 0.0046 0.0057 0.0057
Onchocerca volvulus 0.0066 0.0165 0.0192
Brugia malayi Immunoglobulin I-set domain containing protein 0.0098 0.0332 0.0353
Echinococcus granulosus calcium activated potassium channel 0.01 0.0341 0.0341
Trichomonas vaginalis AGC family protein kinase 0.0223 0.0987 0.4102
Giardia lamblia Kinase, CDC7 0.0066 0.0165 0.1778
Trichomonas vaginalis CMGC family protein kinase 0.0074 0.0205 0.0853
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0057 0.006
Loa Loa (eye worm) SH2 domain-containing protein 0.0039 0.0019 0.002
Schistosoma mansoni protein kinase 0.0048 0.0066 0.0074
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Echinococcus multilocularis hemicentin 1 0.0076 0.0217 0.0471
Echinococcus granulosus CDC7 cell division cycle 7 0.0066 0.0165 0.0165
Onchocerca volvulus 0.0046 0.0057 0.0066
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.006 0.0133 0.0141
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0084 0.0256 0.0555
Loa Loa (eye worm) TK protein kinase 0.0142 0.0564 0.0599
Entamoeba histolytica PH domain containing protein kinase, putative 0.009 0.029 0.2179
Schistosoma mansoni tyrosine kinase 0.0069 0.0179 0.0201
Echinococcus multilocularis raf serine:threonine protein kinase 0.0077 0.022 0.0477
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0028 0.0031
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0103 0.0357 0.3748
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0339 0.0382
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0108 0.0382 0.2892
Schistosoma mansoni hypothetical protein 0.0036 0.0003 0.0004
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0082 0.0247 0.0262
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0036 0.0003 0.0003
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Brugia malayi C1-like domain containing protein 0.0161 0.0663 0.0705
Loa Loa (eye worm) hypothetical protein 0.0039 0.0019 0.002
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0063 0.0145 0.1669
Echinococcus granulosus casein kinase I alpha 0.008 0.0239 0.0239
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.0141 0.0141
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0057 0.0362
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0114 0.0414 0.4349
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Echinococcus multilocularis expressed conserved protein 0.01 0.034 0.0738
Schistosoma mansoni tensin 0.0039 0.0019 0.0021
Brugia malayi Protein kinase domain containing protein 0.0698 0.3488 0.3707
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0731 0.0824
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0165 0.0681 0.148
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.004 0.0023 0.0096
Echinococcus multilocularis heat shock protein 70 0.0046 0.0057 0.0123
Loa Loa (eye worm) hypothetical protein 0.0044 0.0048 0.0051
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.007 0.0185 0.1944
Echinococcus granulosus Immunoglobulin 0.0041 0.0028 0.0028
Echinococcus granulosus nephrin 0.0058 0.0118 0.0118
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0357 0.0402
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0057 0.0362
Trypanosoma cruzi cdc2-related kinase 1 0.0088 0.0278 0.3201
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1823 0.9409 1
Loa Loa (eye worm) serine/threonine protein kinase 0.0046 0.0057 0.006
Echinococcus multilocularis cyclin dependent kinase 0.0088 0.0278 0.0604
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0057 0.0064
Entamoeba histolytica hypothetical protein 0.0046 0.0057 0.0368
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0037 0.001 0.0011
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.004 0.0028 0.0322
Schistosoma mansoni tyrosine kinase 0.0204 0.0889 0.1001
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0084 0.0256 0.0256
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Entamoeba histolytica protein kinase, putative 0.0052 0.0091 0.063
Schistosoma mansoni nephrin related 0.0036 0.0003 0.0004
Echinococcus granulosus neuroglian 0.0183 0.0777 0.0777
Schistosoma mansoni basigin related 0.0041 0.0028 0.0032
Echinococcus multilocularis tyrosine protein kinase csk 0.0046 0.0057 0.0123
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0062 0.0139 0.1408
Entamoeba histolytica ankyrin repeat protein 0.0046 0.0057 0.0362
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0118 0.0126
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0256 0.1162 0.1235
Echinococcus multilocularis Immunoglobulin subtype 0.0041 0.0028 0.0062
Plasmodium vivax serine/threonine kinase-1, putative 0.0114 0.0414 0.9726
Brugia malayi casein kinase 1, delta 0.008 0.0239 0.0254
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0057 0.0235
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0057 0.0362
Schistosoma mansoni tyrosine kinase 0.0347 0.1641 0.1848
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus multilocularis growth factor receptor bound protein 2 0.0069 0.0179 0.0388
Trichomonas vaginalis CMGC family protein kinase 0.0095 0.0317 0.1316
Entamoeba histolytica protein kinase domain containing protein 0.0095 0.0317 0.2383
Schistosoma mansoni hypothetical protein 0.0046 0.0057 0.0064
Leishmania major hypothetical protein, conserved 0.0046 0.0057 0.0651
Loa Loa (eye worm) hypothetical protein 0.0106 0.0372 0.0395
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Echinococcus granulosus cyclin dependent kinase 0.0088 0.0278 0.0278
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0058 0.0118 0.0126
Entamoeba histolytica hypothetical protein 0.0046 0.0057 0.0362
Echinococcus granulosus retinal guanylyl cyclase 2 0.0046 0.0057 0.0057
Brugia malayi Protein kinase domain containing protein 0.0444 0.2154 0.229
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0292 0.1352 0.1437
Loa Loa (eye worm) hypothetical protein 0.0076 0.0217 0.023
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0256 0.0288
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0058 0.0118 0.0126
Brugia malayi Kinase associated domain 1 family protein 0.0075 0.0212 0.0225
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0115 0.0421 0.175
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0075 0.0208 0.4889
Echinococcus granulosus retinal guanylyl cyclase 2 0.0046 0.0057 0.0057
Schistosoma mansoni hypothetical protein 0.0036 0.0003 0.0004
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Brugia malayi Protein kinase domain containing protein 0.0085 0.026 0.0277
Echinococcus multilocularis titin 0.0036 0.0003 0.0007
Schistosoma mansoni hypothetical protein 0.0037 0.0011 0.0012
Echinococcus multilocularis death associated protein kinase 1 0.0628 0.3123 0.6785
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Echinococcus multilocularis casein kinase ii subunit alpha 0.0074 0.0205 0.0446
Brugia malayi basement membrane proteoglycan precursor 0.0041 0.0028 0.003
Trypanosoma cruzi casein kinase, delta isoform, putative 0.008 0.0239 0.2746
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.018 0.0763 0.0763
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Loa Loa (eye worm) CAMK/PKD protein kinase 0.013 0.05 0.0532
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Echinococcus granulosus activated cdc42 kinase 1 0.0046 0.0057 0.0057
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0124 0.047 0.1021
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Schistosoma mansoni tensin-related 0.0039 0.0019 0.0021
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0069 0.0179 0.0201
Brugia malayi SH2 domain containing protein 0.0039 0.0019 0.002
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Echinococcus granulosus cGMP dependent protein kinase 0.01 0.034 0.034
Trypanosoma cruzi aurora B kinase, putative 0.0108 0.0382 0.4399
Echinococcus multilocularis rho associated protein kinase 0.0241 0.1083 0.2352
Schistosoma mansoni protein kinase 0.0321 0.1507 0.1697
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0041 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0085 0.026 0.0276
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0093 0.0306 0.3525
Entamoeba histolytica ankyrin repeat protein 0.0046 0.0057 0.0362
Trichomonas vaginalis set domain proteins, putative 0.0492 0.2406 1
Schistosoma mansoni ste20-related kinase 0.0152 0.0615 0.0692
Brugia malayi Protein kinase domain containing protein 0.0066 0.0165 0.0175
Loa Loa (eye worm) SH2 domain-containing protein 0.0039 0.0019 0.002
Schistosoma mansoni tyrosine kinase 0.0301 0.1399 0.1576
Echinococcus granulosus tyrosine kinase 0.0085 0.026 0.026
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0414 0.0466
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0075 0.0208 0.2186
Loa Loa (eye worm) animal heme peroxidase 0.0036 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0041 0.0028 0.003
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0084 0.0256 0.0555
Loa Loa (eye worm) hypothetical protein 0.0103 0.0356 0.0378
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Loa Loa (eye worm) TK/FAK protein kinase 0.0425 0.2054 0.2183
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0088 0.0278 0.2922
Trichomonas vaginalis TK family protein kinase 0.0047 0.0061 0.0254
Entamoeba histolytica protein kinase, putative 0.0223 0.0987 0.759
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0124 0.047 0.1021
Echinococcus multilocularis tyrosine kinase 0.0046 0.0057 0.0123
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Schistosoma mansoni protein kinase 0.0321 0.1507 0.1697
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0041 0.0028 0.0032
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0084 0.0256 0.6005
Leishmania major serine/threonine-protein kinase, putative 0.0038 0.0013 0.0145
Onchocerca volvulus Tyrosine kinase homolog 0.1671 0.8609 1
Entamoeba histolytica protein kinase , putative 0.0108 0.0382 0.2892
Trichomonas vaginalis protein kinase atn1, putative 0.0046 0.0057 0.0235
Giardia lamblia Kinase, CMGC GSK 0.0095 0.0317 0.355
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0909 0.4602 0.4891
Entamoeba histolytica protein kinase, putative 0.0076 0.0213 0.1578
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0052 0.0091 0.0091
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Trypanosoma cruzi p21-activated kinase 3, putative 0.004 0.0028 0.0322
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.0141 0.0141
Echinococcus multilocularis tyrosine protein kinase otk 0.0076 0.0217 0.0471
Echinococcus granulosus insulin growth factor binding 0.0036 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0046 0.0057 0.0368
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0584 0.2429
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0114 0.0414 0.4765
Echinococcus granulosus lachesin 0.0076 0.0217 0.0217
Echinococcus granulosus mitogen activated protein kinase 11 0.0118 0.0435 0.0435
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.007 0.0182 0.0395
Brugia malayi Myb-like DNA-binding domain containing protein 0.0036 0.0003 0.0003
Schistosoma mansoni basigin related 0.0041 0.0028 0.0032
Schistosoma mansoni serine/threonine RGC 0.0046 0.0057 0.0064
Trichomonas vaginalis CMGC family protein kinase 0.0074 0.0205 0.0853
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0141 0.0159
Schistosoma mansoni nephrin related 0.0041 0.0028 0.0032
Brugia malayi Immunoglobulin I-set domain containing protein 0.0098 0.0332 0.0353
Brugia malayi probable protein kinase 0.0196 0.0848 0.0901
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0321 0.1507 0.3274
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0046 0.0057 0.0123
Brugia malayi Protein kinase domain containing protein 0.0332 0.1564 0.1662
Echinococcus granulosus tyrosine protein kinase Lyn 0.0205 0.0892 0.0892
Loa Loa (eye worm) hypothetical protein 0.0041 0.0028 0.003
Trichomonas vaginalis AGC family protein kinase 0.006 0.0133 0.0551
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0075 0.0208 0.2109
Onchocerca volvulus 0.0046 0.0057 0.0066
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.006
Brugia malayi SH2 domain containing protein 0.0039 0.0019 0.002
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0046 0.0057 0.0235
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0064 0.015 0.015
Schistosoma mansoni protein kinase 0.0046 0.0057 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0061 0.0254
Echinococcus multilocularis roundabout 2 0.0098 0.0332 0.0721
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0039 0.0019 0.0019
Brugia malayi hypothetical protein 0.0039 0.0019 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0063 0.0145 0.1469
Echinococcus granulosus netrin receptor unc 5 0.0078 0.0225 0.0225
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0909 0.4602 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0124 0.0132
Trichomonas vaginalis CMGC family protein kinase 0.0074 0.0205 0.0853
Echinococcus multilocularis cyclin dependent kinase 5 0.0088 0.0278 0.0604
Plasmodium falciparum calcium-dependent protein kinase 4 0.0075 0.0208 0.4733
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0174 0.0731 0.0731
Schistosoma mansoni tyrosine kinase 0.0115 0.042 0.0474
Loa Loa (eye worm) hypothetical protein 0.0083 0.0251 0.0266
Loa Loa (eye worm) thyroid receptor interactor 0.0087 0.0271 0.0288
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0057 0.0362
Trypanosoma cruzi protein kinase, putative 0.0046 0.0057 0.0651
Echinococcus multilocularis ephrin type A receptor 4 A 0.0093 0.0306 0.0665
Loa Loa (eye worm) hypothetical protein 0.0039 0.0022 0.0023
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Leishmania major protein kinase, putative 0.0108 0.0382 0.4399
Brugia malayi Protein kinase domain containing protein 0.0261 0.119 0.1264
Loa Loa (eye worm) hypothetical protein 0.0041 0.0028 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0084 0.0256 0.5883
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0038 0.0013 0.0145
Schistosoma mansoni netrin receptor unc5 0.0041 0.0028 0.0032
Entamoeba histolytica tyrosin kinase, putative 0.0046 0.0057 0.0362
Schistosoma mansoni hypothetical protein 0.0036 0.0003 0.0004
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0057 0.0362
Trichomonas vaginalis TKL family protein kinase 0.0047 0.0061 0.0254
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Echinococcus multilocularis casein kinase I alpha 0.008 0.0239 0.0518
Echinococcus multilocularis titin 0.0082 0.0247 0.0536
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0084 0.0256 0.2942
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0037 0.0012 0.0013
Echinococcus granulosus titin 0.0036 0.0003 0.0003
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0143 0.0567 0.0602
Brugia malayi Protein kinase domain containing protein 0.0223 0.0987 0.1049
Schistosoma mansoni titin 0.0082 0.0247 0.0278
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0306 0.0664
Echinococcus multilocularis myotubularin protein 13 0.0038 0.0013 0.0028
Brugia malayi Protein kinase domain containing protein 0.0149 0.0598 0.0635
Brugia malayi Pre-SET motif family protein 0.0062 0.0141 0.015
Entamoeba histolytica tyrosin kinase, putative 0.0046 0.0057 0.0362
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.0809 0.0911
Echinococcus multilocularis serine:threonine protein kinase N2 0.0096 0.032 0.0696
Echinococcus granulosus hypothetical protein 0.0039 0.0019 0.0019
Echinococcus multilocularis kinase suppressor of Ras 1 0.0046 0.0057 0.0123
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0869 0.3611
Schistosoma mansoni shc transforming protein 0.0039 0.0019 0.0021
Loa Loa (eye worm) RhoGAP domain-containing protein 0.007 0.0182 0.0193
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0057 0.0362
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0064 0.015 0.015
Schistosoma mansoni nck2/grb4 0.0069 0.0179 0.0201
Toxoplasma gondii protein kinase domain-containing protein 0.0046 0.0057 0.0594
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.004 0.0028 0.003
Loa Loa (eye worm) hypothetical protein 0.0039 0.0019 0.002
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0036 0.0004 0.0004
Loa Loa (eye worm) DOMON domain-containing protein 0.0174 0.0731 0.0777
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0141 0.0588
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0088 0.0278 0.0296
Loa Loa (eye worm) hypothetical protein 0.0083 0.0251 0.0266
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0118 0.0126
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0261 0.119 0.119
Schistosoma mansoni tyrosine kinase 0.0366 0.174 0.1959
Brugia malayi Immunoglobulin domain containing protein 0.0041 0.0028 0.003
Loa Loa (eye worm) hypothetical protein 0.0143 0.057 0.0606
Trichomonas vaginalis AGC family protein kinase 0.0223 0.0987 0.4102
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0057 0.0362
Echinococcus granulosus casein kinase I alpha 0.008 0.0239 0.0239
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Echinococcus granulosus fibroblast growth factor receptor 4 0.0193 0.083 0.083
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0038 0.0013 0.0128
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0261 0.119 0.1264
Trypanosoma cruzi polo-like protein kinase, putative 0.02 0.0869 1
Brugia malayi Receptor family ligand binding region containing protein 0.0046 0.0057 0.006
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0046 0.0057 0.0057
Echinococcus granulosus leucine rich repeat containing protein 4 0.0036 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0909 0.4602 0.4891
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Plasmodium falciparum calcium-dependent protein kinase 1 0.0075 0.0208 0.4733
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0149 0.0598 0.1298
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0046 0.0057 0.006
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.119 0.134
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Schistosoma mansoni hypothetical protein 0.0075 0.0212 0.0239
Echinococcus granulosus nervana 2 0.0092 0.0297 0.0297
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Brugia malayi kettin 0.0036 0.0003 0.0003
Entamoeba histolytica receptor protein kinase, putative 0.0046 0.0057 0.0362
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0187 0.0798 0.0798
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.006
Echinococcus multilocularis serine:threonine protein kinase 3 0.019 0.0816 0.1774
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0041 0.0028 0.0032
Schistosoma mansoni cell adhesion molecule 0.0041 0.0028 0.0032
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0114 0.0414 0.4765
Schistosoma mansoni tyrosine kinase 0.0122 0.0458 0.0516
Loa Loa (eye worm) TK/EGFR protein kinase 0.0533 0.2621 0.2786
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0062 0.0144 0.0144
Plasmodium falciparum casein kinase 1 0.008 0.0239 0.5471
Brugia malayi Protein kinase c protein 2 0.0086 0.0266 0.0283
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Brugia malayi SH2 domain containing protein 0.0039 0.0019 0.002
Brugia malayi Fes/CIP4 homology domain containing protein 0.0087 0.0271 0.0288
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.0141 0.0307
Schistosoma mansoni tensin-related 0.0039 0.0019 0.0021
Echinococcus multilocularis mitogen activated protein kinase 11 0.0118 0.0435 0.0946
Echinococcus multilocularis tyrosine kinase 0.0085 0.026 0.0565
Trichomonas vaginalis STE family protein kinase 0.0038 0.0013 0.0053
Brugia malayi Immunoglobulin I-set domain containing protein 0.0169 0.0704 0.0749
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0003 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Schistosoma mansoni hypothetical protein 0.0058 0.0118 0.0133
Brugia malayi serine/threonine protein kinase 6 0.0108 0.0382 0.0406
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0187 0.0798 0.0848
Echinococcus multilocularis epidermal growth factor receptor 0.0533 0.2621 0.5695
Echinococcus multilocularis Immunoglobulin 0.0041 0.0028 0.0062
Schistosoma mansoni titin 0.0058 0.0118 0.0133
Echinococcus multilocularis dual specificity 0.0091 0.0292 0.0633
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0085 0.026 0.0276
Brugia malayi SH2 domain containing protein 0.0039 0.0019 0.002
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0098 0.0332 0.0353
Schistosoma mansoni cell adhesion molecule 0.0041 0.0028 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0013 0.0053
Brugia malayi Immunoglobulin I-set domain containing protein 0.0076 0.0217 0.023
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.006
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0103 0.0357 0.3616
Echinococcus granulosus dual specificity 0.0103 0.0357 0.0357
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.0141 0.1504
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.007 0.0185 0.213
Echinococcus multilocularis hypothetical protein 0.0075 0.0212 0.0461
Leishmania major casein kinase, putative 0.008 0.0239 0.2746
Leishmania major protein kinase, putative 0.0114 0.0414 0.4765
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0083 0.0251 0.2885
Entamoeba histolytica protein kinase, putative 0.0062 0.0139 0.1002
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.006
Echinococcus granulosus NCK adaptor protein 0.0069 0.0179 0.0179
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.016 0.0657 0.1428
Echinococcus multilocularis titin 0.0036 0.0003 0.0007
Echinococcus multilocularis cyclin dependent kinase 1 0.0088 0.0278 0.0604
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus granulosus roundabout 2 0.0098 0.0332 0.0332
Schistosoma mansoni septate junction protein 0.0076 0.0217 0.0244
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.0141 0.1433
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0039 0.0019 0.002
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0066 0.0163 0.1882
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.006 0.0133 0.0288
Echinococcus multilocularis tyrosine protein kinase Fyn 0.015 0.0603 0.1311
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Brugia malayi MAP kinase sur-1 0.0062 0.0141 0.015
Schistosoma mansoni serine/threonine kinase 0.0124 0.047 0.0529
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0036 0.0004 0.0009
Trichomonas vaginalis STE family protein kinase 0.0101 0.0346 0.1437
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Onchocerca volvulus 0.0047 0.0065 0.0075
Brugia malayi Protein kinase domain containing protein 0.0091 0.0292 0.031
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0003 0.0003
Brugia malayi protein-tyrosine kinase 0.015 0.0603 0.0641
Trypanosoma cruzi casein kinase II, putative 0.0074 0.0205 0.2362
Trypanosoma brucei Casein kinase II 0.0074 0.0205 0.208
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0076 0.0217 0.0252
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.008 0.0239 0.0254
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0141 0.0588
Schistosoma mansoni protein kinase 0.0185 0.0791 0.0891
Giardia lamblia Kinase, CMGC CDK 0.0088 0.0278 0.3101
Trichomonas vaginalis AGC family protein kinase 0.0101 0.0346 0.1437
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0238 0.1069 0.2323
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0062 0.0139 0.1599
Loa Loa (eye worm) TK/FER protein kinase 0.0181 0.0767 0.0815
Onchocerca volvulus 0.0046 0.0057 0.0066
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0091 0.0292 0.3356
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0087 0.0271 0.0288
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0084 0.0256 0.0256
Schistosoma mansoni hypothetical protein 0.0041 0.0028 0.0032
Schistosoma mansoni hypothetical protein 0.0036 0.0003 0.0004
Echinococcus granulosus Protein kinase C brain isozyme 0.0186 0.0792 0.0792
Giardia lamblia Kinase, AGC PKA 0.0116 0.0426 0.4824
Loa Loa (eye worm) AGC/PKN protein kinase 0.022 0.0975 0.1037
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0098 0.0332 0.0332
Brugia malayi Sex muscle abnormal protein 5 0.0069 0.0179 0.019
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0039 0.0019 0.002
Echinococcus granulosus N chimaerin 0.007 0.0182 0.0182
Echinococcus multilocularis transfer RNA-Phe 0.0058 0.0118 0.0257
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0095 0.0317 0.3644
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0092 0.0297 0.0646
Loa Loa (eye worm) SRC-1 0.018 0.0763 0.0811
Loa Loa (eye worm) one IG domain family member 0.0036 0.0003 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Toxoplasma gondii CMGC kinase, CK2 family 0.0074 0.0205 0.2156
Echinococcus multilocularis Ankyrin 0.0037 0.0012 0.0025
Brugia malayi cell division control protein 2 homolog 0.0088 0.0278 0.0296
Entamoeba histolytica casein kinase, putative 0.0074 0.0205 0.1517
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0084 0.0256 0.259
Brugia malayi SRC-1 0.018 0.0763 0.0811
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0047 0.0064 0.0068
Echinococcus granulosus tyrosine protein kinase shark 0.0243 0.1093 0.1093
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0046 0.0057 0.0573
Echinococcus granulosus integrin linked protein kinase 0.0046 0.0057 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0138 0.0539 0.1172
Plasmodium vivax tyrosine kinase-like protein, putative 0.0046 0.0057 0.1329
Trichomonas vaginalis AGC family protein kinase 0.0108 0.0382 0.1589
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0357 0.1483
Trypanosoma cruzi polo-like protein kinase, putative 0.02 0.0869 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0141 0.0307
Echinococcus granulosus titin 0.0082 0.0247 0.0247
Brugia malayi Pleckstrin Homology Domain 0.0038 0.0013 0.0014
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0046 0.0057 0.0057
Giardia lamblia Kinase, NEK 0.0101 0.0346 0.3891
Plasmodium falciparum tyrosine kinase-like protein 0.0046 0.0057 0.1063
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0138 0.0539 0.0539
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.022 0.0247
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0163 0.0184
Echinococcus multilocularis insulin growth factor binding 0.0036 0.0003 0.0007
Echinococcus granulosus protein tyrosine kinase 0.0421 0.203 0.203
Brugia malayi Protein kinase domain containing protein 0.0158 0.0646 0.0687
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0132 0.0148
Schistosoma mansoni protein kinase 0.0046 0.0057 0.0064
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0046 0.0058 0.0241
Echinococcus granulosus protein kinase c epsilon type 0.0156 0.0638 0.0638
Brugia malayi Immunoglobulin I-set domain containing protein 0.0082 0.0247 0.0262
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0088 0.0278 0.3201
Loa Loa (eye worm) TK/Met protein kinase 0.0046 0.0057 0.006
Schistosoma mansoni tyrosine kinase 0.0243 0.1093 0.1231
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0095 0.0317 0.3644
Schistosoma mansoni protein kinase 0.0064 0.015 0.0169
Onchocerca volvulus 0.0103 0.0356 0.0414
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0098 0.0332 0.0721
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0105 0.0369 0.0802
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0046 0.0057 0.0235
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0255 0.1157 0.123
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0046 0.0057 0.006
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0075 0.0208 0.0221
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0084 0.0256 0.259
Echinococcus granulosus protein kinase c iota type 0.0217 0.0956 0.0956
Loa Loa (eye worm) hypothetical protein 0.0066 0.0163 0.0173
Echinococcus multilocularis calcium activated potassium channel 0.01 0.0341 0.074
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0036 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0111 0.0401 0.0426
Schistosoma mansoni protein kinase 0.0046 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Onchocerca volvulus 0.0039 0.0019 0.0022
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.026 0.0277
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.026 0.0277
Entamoeba histolytica protein kinase, putative 0.0223 0.0987 0.759
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0332 0.1564 0.1662
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.026 0.0277
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.006 0.0131 0.1374
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0216 0.0952 0.1012
Trypanosoma cruzi cdc2-related kinase 3 0.0088 0.0278 0.3201
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0075 0.0208 0.0452
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0046 0.0057 0.0064
Echinococcus granulosus retinal guanylyl cyclase 2 0.0046 0.0057 0.0057
Trichomonas vaginalis STE family protein kinase 0.0063 0.0145 0.0603
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.006
Giardia lamblia Kinase, AGC PKA 0.0084 0.0256 0.2838
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0057 0.0235
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.047 0.0529
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.026 0.0277
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus granulosus SH2 domain containing adapter protein F 0.0039 0.0019 0.0019
Brugia malayi Protein kinase domain containing protein 0.0114 0.0414 0.044
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0247 0.1114 0.1184
Schistosoma mansoni cell adhesion molecule 0.0098 0.0332 0.0374
Echinococcus granulosus hypothetical protein 0.0089 0.0285 0.0285
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0196 0.0845 0.1837
Echinococcus granulosus homeodomain interacting protein kinase 3 0.015 0.0605 0.0605
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.0141 0.1485
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0292 0.1352 0.1352
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0181 0.0767 0.0767
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.0792 0.0892
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0046 0.0057 0.0123
Echinococcus multilocularis serine:threonine protein kinase 0.0085 0.026 0.0565
Trichomonas vaginalis CAMK family protein kinase 0.0075 0.0208 0.0865
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.026 0.0277
Plasmodium falciparum serine/threonine protein kinase 0.0062 0.0139 0.3058
Trypanosoma brucei cdc2-related kinase 3 0.0088 0.0278 0.2818
Plasmodium vivax tyrosine kinase-like protein, putative 0.0046 0.0057 0.1329
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0084 0.0256 0.2685
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0066 0.0163 0.1882
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0161 0.0663 0.0705
Loa Loa (eye worm) hypothetical protein 0.0049 0.0072 0.0076
Echinococcus granulosus Immunoglobulin subtype 0.0041 0.0028 0.0028
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.016 0.0657 0.1428
Echinococcus multilocularis tyrosine protein kinase Src42A 0.018 0.0763 0.1659
Giardia lamblia Kinase, AGC AKT 0.0087 0.0271 0.3022
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0076 0.0217 0.023
Echinococcus multilocularis nervana 2 0.0092 0.0297 0.0646
Schistosoma mansoni hypothetical protein 0.0039 0.0019 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0163 0.0184
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0023 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.02 0.0869 0.0978
Brugia malayi putative serine/threonine kinase SADA gamma 0.0066 0.0163 0.0174
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0366 0.1743 0.1743
Giardia lamblia Aurora kinase 0.0108 0.0382 0.4316
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Schistosoma mansoni titin 0.0036 0.0003 0.0004
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0046 0.0057 0.0362
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0036 0.0003 0.0003
Entamoeba histolytica protein kinase, putative 0.0075 0.0208 0.1539
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Schistosoma mansoni titin 0.0036 0.0003 0.0004
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0082 0.0245 0.0532
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus granulosus casein kinase I gamma 0.0158 0.0646 0.0646
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0046 0.0058 0.0241
Entamoeba histolytica protein kinase, putative 0.0052 0.0091 0.063
Entamoeba histolytica protein kinase, putative 0.0063 0.0147 0.1065
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0208 0.0234
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.006
Loa Loa (eye worm) hypothetical protein 0.0039 0.0019 0.002
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0075 0.0208 0.2186
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0272 0.1245 0.2705
Schistosoma mansoni titin 0.0036 0.0003 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0088 0.0278 0.1156
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0141 0.1627
Loa Loa (eye worm) hypothetical protein 0.0147 0.059 0.0627
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.0141 0.015
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0161 0.0663 0.0705
Loa Loa (eye worm) hypothetical protein 0.0134 0.0519 0.0552
Entamoeba histolytica protein kinase, putative 0.0091 0.0292 0.2188
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0084 0.0256 0.2942
Echinococcus granulosus defective proboscis extension response 0.0147 0.0589 0.0589
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0098 0.0332 0.0721
Trichomonas vaginalis STE family protein kinase 0.0064 0.015 0.0625
Echinococcus multilocularis netrin receptor unc 5 0.0078 0.0225 0.0488
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0388 0.1855 0.4031
Schistosoma mansoni tensin 0.0039 0.0019 0.0021
Brugia malayi Peroxidasin 0.0077 0.0218 0.0231
Schistosoma mansoni hypothetical protein 0.0041 0.0028 0.0032
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0092 0.0297 0.0297
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Echinococcus granulosus epidermal growth factor receptor 0.0533 0.2621 0.2621
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0013 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0091 0.0103
Echinococcus multilocularis myosin iiia 0.0063 0.0145 0.0315
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0003 0.0003
Brugia malayi hypothetical protein 0.0165 0.0681 0.0724
Onchocerca volvulus Netrin receptor homolog 0.0073 0.0199 0.0231
Entamoeba histolytica protein kinase, putative 0.0054 0.0101 0.0704
Trypanosoma cruzi protein kinase, putative 0.0046 0.0057 0.0651
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0041 0.0028 0.0032
Echinococcus granulosus dual specificity 0.0091 0.0292 0.0292
Plasmodium falciparum calcium-dependent protein kinase 3 0.0075 0.0208 0.4733
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0046 0.0057 0.0057
Echinococcus granulosus tyrosine protein kinase Fyn 0.018 0.0763 0.0763
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0163 0.0184
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0225 0.0998 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.006
Entamoeba histolytica PH domain containing protein kinase, putative 0.009 0.029 0.2179
Schistosoma mansoni tyrosine kinase 0.018 0.0763 0.086
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0075 0.0208 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0057 0.0235
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0046 0.0057 0.006
Onchocerca volvulus 0.0046 0.0057 0.0066
Echinococcus multilocularis activated cdc42 kinase 1 0.0046 0.0057 0.0123
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0083 0.0251 0.254
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0156 0.0638 0.0678
Echinococcus multilocularis casein kinase I alpha 0.008 0.0239 0.0518
Echinococcus multilocularis tyrosine protein kinase pr2 0.0046 0.0057 0.0123
Brugia malayi Variant SH3 domain containing protein 0.0069 0.0179 0.019
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0075 0.0208 0.0452
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0108 0.0382 0.2892
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0256 0.0288
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.0141 0.1627
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0046 0.0057 0.0123
Echinococcus granulosus serine:threonine protein kinase NLK 0.0136 0.0529 0.0529
Echinococcus multilocularis protein kinase c iota type 0.0217 0.0956 0.2077
Brugia malayi serine/threonine kinase 12 0.0108 0.0382 0.0406
Loa Loa (eye worm) hypothetical protein 0.0039 0.0019 0.002
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0114 0.0414 0.4195
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0057 0.006
Entamoeba histolytica protein kinase, putative 0.0111 0.04 0.3027
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Plasmodium falciparum cGMP-dependent protein kinase 0.01 0.034 0.792
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0598 0.0673
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0084 0.0256 0.259
Trichomonas vaginalis CK1 family protein kinase 0.008 0.0239 0.0992
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0141 0.0588
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Brugia malayi Protein kinase domain containing protein 0.0136 0.0529 0.0562
Echinococcus granulosus Vam6:Vps39 protein 0.0083 0.0251 0.0251
Loa Loa (eye worm) hypothetical protein 0.0223 0.0991 0.1053
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0141 0.0307
Leishmania major protein kinase, putative 0.0075 0.0208 0.2395
Echinococcus granulosus Immunoglobulin 0.0041 0.0028 0.0028
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0041 0.0028 0.0062
Trichomonas vaginalis CMGC family protein kinase 0.0074 0.0205 0.0853
Brugia malayi Variant SH3 domain containing protein 0.0069 0.0179 0.019
Onchocerca volvulus 0.0085 0.026 0.0302
Brugia malayi Immunoglobulin I-set domain containing protein 0.0078 0.0225 0.0239
Entamoeba histolytica serine/threonine protein kinase, putative 0.02 0.0869 0.6673
Toxoplasma gondii aurora kinase 0.0108 0.0382 0.4015
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0039 0.0019 0.004
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Plasmodium falciparum protein kinase 5 0.0088 0.0278 0.6429
Echinococcus multilocularis serine:threonine protein kinase 38 0.0124 0.047 0.1021
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Brugia malayi protein kinase C3,putative 0.0117 0.043 0.0457
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0116 0.0426 0.4899
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0046 0.0057 0.0123
Echinococcus granulosus cyclin dependent kinase 5 0.0088 0.0278 0.0278
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0116 0.0426 1
Echinococcus granulosus rho-associated protein kinase 1 0.0241 0.1083 0.1083
Echinococcus multilocularis protein kinase 0.0046 0.0057 0.0123
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0059 0.0127 0.0127
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Loa Loa (eye worm) TK/ACK protein kinase 0.0046 0.0057 0.006
Schistosoma mansoni growth factor receptor-bound protein 0.0071 0.0187 0.021
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0256 0.0288
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0172 0.072 0.0765
Echinococcus multilocularis tensin 0.0039 0.0019 0.004
Schistosoma mansoni signal transduction protein lnk-related 0.0039 0.0019 0.0021
Echinococcus granulosus SH2 domain containing protein 7 0.0039 0.0019 0.0019
Entamoeba histolytica serine/threonine protein kinase, putative 0.0038 0.0013 0.0021
Echinococcus granulosus tyrosine protein kinase Src42A 0.018 0.0763 0.0763
Brugia malayi ephrin receptor 1 precursor 0.0068 0.0174 0.0185
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Loa Loa (eye worm) hypothetical protein 0.0069 0.0179 0.019
Onchocerca volvulus 0.0039 0.0019 0.0022
Entamoeba histolytica protein kinase, putative 0.006 0.0133 0.0953
Loa Loa (eye worm) TK protein kinase 0.0046 0.0057 0.006
Schistosoma mansoni ephrin receptor 0.0068 0.0172 0.0193
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0057 0.0235
Loa Loa (eye worm) hypothetical protein 0.0039 0.0019 0.002
Echinococcus multilocularis Immunoglobulin 0.0041 0.0028 0.0062
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.02 0.0869 0.0923
Loa Loa (eye worm) AGC/PKA protein kinase 0.0084 0.0256 0.0272
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0869 0.3611
Loa Loa (eye worm) TK protein kinase 0.0046 0.0057 0.006
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0247 0.0278
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Loa Loa (eye worm) hypothetical protein 0.0106 0.0375 0.0398
Brugia malayi Pre-SET motif family protein 0.0432 0.2091 0.2222
Trypanosoma brucei protein kinase, putative 0.007 0.0185 0.1875
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0041 0.0028 0.0062
Onchocerca volvulus Peroxidasin homolog 0.0036 0.0003 0.0004
Trichomonas vaginalis AGC family protein kinase 0.0223 0.0987 0.4102
Plasmodium falciparum protein serine/threonine kinase-1 0.0114 0.0414 0.9718
Schistosoma mansoni serine/threonine protein kinase 0.0136 0.0529 0.0596
Brugia malayi jmjC domain containing protein 0.0093 0.0306 0.0325
Onchocerca volvulus 0.0095 0.0317 0.0368
Brugia malayi hypothetical protein 0.0046 0.0057 0.006
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0186 0.0792 0.1722
Onchocerca volvulus 0.0062 0.0141 0.0164
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Onchocerca volvulus 0.0046 0.0057 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0163 0.0184
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0414 0.0466
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0115 0.042 0.0474
Brugia malayi Protein kinase domain containing protein 0.0124 0.047 0.0499
Schistosoma mansoni protein kinase 0.0108 0.0382 0.043
Loa Loa (eye worm) hypothetical protein 0.0169 0.0704 0.0749
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0057 0.0362
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0187 0.0798 0.1733
Echinococcus multilocularis activin receptor type 0.007 0.0185 0.0402
Trichomonas vaginalis AGC family protein kinase 0.0108 0.0382 0.1589
Echinococcus multilocularis SH2 motif 0.0039 0.0019 0.004
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.004 0.0028 0.003
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0869 0.3611
Loa Loa (eye worm) CAMK protein kinase 0.0082 0.0247 0.0262
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0036 0.0003 0.0003
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0101 0.0346 0.8123
Schistosoma mansoni septate junction protein 0.0041 0.0028 0.0032
Echinococcus multilocularis expressed protein 0.0062 0.0139 0.0302
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Echinococcus multilocularis tyrosine protein kinase Blk 0.015 0.0603 0.1311
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0118 0.0126
Brugia malayi SH2 domain containing protein 0.0039 0.0019 0.002
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0095 0.0317 0.0336
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0174 0.0731 0.1589
Loa Loa (eye worm) TK protein kinase 0.015 0.0603 0.0641
Loa Loa (eye worm) hypothetical protein 0.0076 0.0217 0.023
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0057 0.006
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0149 0.0598 0.0598
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0103 0.0357 0.4107
Entamoeba histolytica hypothetical protein 0.0046 0.0057 0.0362
Plasmodium vivax tyrosine kinase-like protein, putative 0.006 0.0131 0.3072
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0046 0.0057 0.0368
Echinococcus granulosus c src tyrosine kinase 0.0115 0.042 0.042
Schistosoma mansoni septate junction protein 0.0041 0.0028 0.0032
Toxoplasma gondii AGC kinase 0.0084 0.0256 0.2685
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0057 0.0362
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0347 0.1641 0.1641
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Brugia malayi Protein kinase domain containing protein 0.006 0.0133 0.0141
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0141 0.0159
Plasmodium vivax glycogen synthase kinase 3, putative 0.0095 0.0317 0.7439
Schistosoma mansoni protein kinase 0.0046 0.0057 0.0064
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0075 0.0208 0.0221
Echinococcus multilocularis transfer RNA-Thr 0.0046 0.0057 0.0123
Echinococcus granulosus epidermal growth factor receptor 0.0347 0.1641 0.1641
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0116 0.0426 0.0925
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Loa Loa (eye worm) hypothetical protein 0.0088 0.0279 0.0296
Loa Loa (eye worm) protein kinase domain-containing protein 0.0158 0.0646 0.0687
Echinococcus multilocularis serine:threonine protein kinase 0.0085 0.026 0.0565
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0057 0.0362
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.006
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0052 0.0091 0.0198
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Trichomonas vaginalis CAMK family protein kinase 0.0085 0.0264 0.1096
Echinococcus multilocularis protein tyrosine kinase 0.0421 0.203 0.4411
Schistosoma mansoni atypical protein kinase C 0.0221 0.098 0.1103
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.015 0.0603 0.0603
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.008 0.0239 0.0254
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.0141 0.0307
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.015 0.0605 0.0643
Echinococcus multilocularis tyrosine protein kinase Abl 0.0174 0.073 0.1585
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.026 0.0277
Echinococcus granulosus protein kinase shaggy 0.0095 0.0317 0.0317
Trichomonas vaginalis AGC family protein kinase 0.0223 0.0987 0.4102
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.006
Toxoplasma gondii protein kinase 0.0046 0.0057 0.0594
Echinococcus multilocularis 0.0039 0.0019 0.004
Brugia malayi P38 map kinase family protein 2 0.0118 0.0435 0.0463
Loa Loa (eye worm) hypothetical protein 0.0227 0.1011 0.1074
Echinococcus granulosus Ankyrin 0.0037 0.0012 0.0012
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0388 0.1855 0.1855
Entamoeba histolytica protein kinase, putative 0.0062 0.0139 0.1002
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0075 0.0208 0.4889
Schistosoma mansoni peptidylglycine monooxygenase 0.0909 0.4602 0.5183
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0118 0.0126
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0003 0.0003
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0261 0.119 0.2585
Echinococcus granulosus roundabout 2 0.0245 0.1106 0.1106
Onchocerca volvulus 0.0036 0.0003 0.0004
Brugia malayi phosphoinositide-dependent protein kinase I 0.006 0.0133 0.0141
Entamoeba histolytica protein kinase, putative 0.0108 0.0382 0.2892
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0075 0.0208 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0308 0.1279
Loa Loa (eye worm) hypothetical protein 0.0045 0.0053 0.0057
Schistosoma mansoni netrin receptor unc5 0.0078 0.0225 0.0253
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Trypanosoma brucei Pseudokinase, putative 0.0046 0.0057 0.0573
Schistosoma mansoni hypothetical protein 0.0041 0.0028 0.0032
Onchocerca volvulus 0.0085 0.026 0.0302
Loa Loa (eye worm) hypothetical protein 0.0066 0.0163 0.0174
Schistosoma mansoni SH2A 0.0039 0.0019 0.0021
Echinococcus multilocularis integrin linked protein kinase 0.0046 0.0057 0.0123
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0147 0.0589 0.0664
Schistosoma mansoni hypothetical protein 0.0041 0.0028 0.0032
Schistosoma mansoni tyrosine kinase 0.02 0.0865 0.0975
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0108 0.0382 0.083
Schistosoma mansoni peroxidasin 0.0041 0.0029 0.0033
Echinococcus multilocularis protein kinase 0.0046 0.0057 0.0123
Onchocerca volvulus Serine\/threonine kinase homolog 0.02 0.0869 0.1009
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Entamoeba histolytica hypothetical protein 0.0046 0.0057 0.0362
Toxoplasma gondii NEK kinase 0.0038 0.0013 0.0133
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Loa Loa (eye worm) AGC/PKG protein kinase 0.01 0.034 0.0361
Brugia malayi STE20-like kinase MST 0.019 0.0816 0.0868
Entamoeba histolytica protein kinase domain containing protein 0.0048 0.0069 0.0458
Echinococcus granulosus kinase suppressor of Ras 1 0.0046 0.0057 0.0057
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Echinococcus multilocularis signal transduction protein lnk realted 0.0039 0.0019 0.004
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0256 0.1062
Brugia malayi cytokine inducible SH2-containing protein 5 0.0039 0.0019 0.002
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Echinococcus granulosus raf serine:threonine protein kinase 0.0077 0.022 0.022
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.018 0.0763 0.1659
Leishmania major protein kinase, putative 0.0063 0.0145 0.1669
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0909 0.4602 0.5183
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0037 0.0011 0.0012
Echinococcus multilocularis SHC transforming protein 3 0.0039 0.0019 0.004
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0147 0.0589 0.128
Brugia malayi hypothetical protein 0.0041 0.0028 0.003
Trichomonas vaginalis CMGC family protein kinase 0.0088 0.0278 0.1156
Echinococcus granulosus tyrosine kinase 0.0046 0.0057 0.0057
Echinococcus multilocularis titin 0.0036 0.0003 0.0007
Echinococcus multilocularis tyrosine protein kinase Fyn 0.018 0.0763 0.1659
Echinococcus multilocularis tensin 0.0039 0.0019 0.004
Echinococcus granulosus tyrosine protein kinase otk 0.0076 0.0217 0.0217
Mycobacterium ulcerans hypothetical protein 0.0075 0.0211 1
Schistosoma mansoni growth factor receptor-bound protein 0.0069 0.0179 0.0201
Plasmodium falciparum serine/threonine protein kinase KIN 0.0066 0.0163 0.3653
Schistosoma mansoni protein kinase 0.0046 0.0057 0.0064
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0141 0.1485
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0084 0.0256 0.0555
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0462 0.2244 0.2385
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0046 0.0057 0.0066
Plasmodium vivax unspecified product 0.0074 0.0205 0.4822
Echinococcus multilocularis protein kinase c epsilon type 0.0156 0.0638 0.1386
Onchocerca volvulus 0.008 0.0239 0.0277
Plasmodium falciparum protein kinase, putative 0.0046 0.0057 0.1063
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0681 0.0767
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Onchocerca volvulus 0.0036 0.0003 0.0004
Echinococcus multilocularis casein kinase I delta 0.008 0.0239 0.0518
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0118 0.0435 0.4412
Onchocerca volvulus Peroxidasin homolog 0.0036 0.0004 0.0005
Entamoeba histolytica hypothetical protein 0.0046 0.0057 0.0362
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0083 0.0251 0.0282
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0118 0.0435 0.5011
Giardia lamblia Kinase, STE STE20 0.0064 0.015 0.1608
Trypanosoma brucei polo-like protein kinase 0.02 0.0869 0.8804
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0798 0.0898
Brugia malayi Prion-like- 0.0036 0.0003 0.0003
Echinococcus granulosus SHC transforming protein 3 0.0039 0.0019 0.0019
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0036 0.0003 0.0003
Echinococcus granulosus tyrosine protein kinase pr2 0.0046 0.0057 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Schistosoma mansoni protein kinase 0.0272 0.1245 0.1402
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0095 0.0317 0.3326
Echinococcus multilocularis 0.0036 0.0003 0.0007
Schistosoma mansoni protein kinase 0.0064 0.015 0.0169
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0037 0.001 0.0022
Echinococcus granulosus serine:threonine protein kinase N2 0.0096 0.032 0.032
Echinococcus granulosus activated cdc42 kinase 1 0.0046 0.0057 0.0057
Brugia malayi Cam kinase protein 1 0.0075 0.0208 0.0221
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0366 0.1743 0.3786
Trichomonas vaginalis AGC family protein kinase 0.004 0.0023 0.0096
Brugia malayi RhoGAP domain containing protein 0.007 0.0182 0.0193
Loa Loa (eye worm) hypothetical protein 0.0037 0.0012 0.0012
Entamoeba histolytica SH2 domain containing protein 0.0039 0.0019 0.0067
Echinococcus multilocularis mitogen activated protein kinase 14 0.0118 0.0435 0.0946
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Onchocerca volvulus 0.0085 0.026 0.0302
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0122 0.0455 0.0455
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.007 0.0182 0.0205
Brugia malayi Immunoglobulin I-set domain containing protein 0.0076 0.0217 0.023
Echinococcus granulosus cGMP dependent protein kinase 1 0.01 0.034 0.034
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus multilocularis casein kinase i 0.008 0.0239 0.0518
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0039 0.0019 0.0021
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Loa Loa (eye worm) TK protein kinase 0.0224 0.0991 0.1054
Onchocerca volvulus 0.0036 0.0003 0.0004
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.004 0.0028 0.003
Onchocerca volvulus 0.0036 0.0003 0.0004
Onchocerca volvulus 0.0046 0.0057 0.0066
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0003 0.0003
Entamoeba histolytica casein kinase 1, putative 0.008 0.0239 0.1776
Loa Loa (eye worm) hypothetical protein 0.0223 0.0991 0.1053
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0139 0.0156
Loa Loa (eye worm) TK protein kinase 0.0046 0.0057 0.006
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0036 0.0003 0.0003
Entamoeba histolytica protein kinase, putative 0.0103 0.0357 0.2695
Echinococcus multilocularis protein KINase family member (kin 25) 0.0046 0.0057 0.0123
Echinococcus multilocularis tyrosine protein kinase Fgr 0.018 0.0763 0.1659
Giardia lamblia Kinase, CMGC DYRK 0.0103 0.0357 0.402
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.014 0.0549 0.0584
Echinococcus granulosus insulin receptor 0.0366 0.174 0.174
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0432 0.2091 0.2222
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0118 0.0435 0.5011
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0368
Trichomonas vaginalis CMGC family protein kinase 0.0074 0.0205 0.0853
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0129 0.0129
Schistosoma mansoni roundabout 0.0076 0.0217 0.0244
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0095 0.0317 0.0688
Trichomonas vaginalis CMGC family protein kinase 0.0074 0.0205 0.0853
Echinococcus granulosus suppressor of cytokine signaling 7 0.0039 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0135 0.0526 0.0559
Onchocerca volvulus 0.0046 0.0057 0.0066
Schistosoma mansoni slit 0.0036 0.0004 0.0005
Loa Loa (eye worm) AGC/NDR protein kinase 0.0124 0.047 0.0499
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0084 0.0256 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0061 0.0254
Echinococcus multilocularis serine threonine protein kinase 0.0155 0.0629 0.1367
Brugia malayi Immunoglobulin domain containing protein 0.0041 0.0028 0.003
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0039 0.0019 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.01 0.034 0.0383
Brugia malayi Temporarily assigned gene name protein 59 0.0096 0.0318 0.0338
Brugia malayi Casein kinase II, alpha chain 0.0074 0.0205 0.0218
Echinococcus granulosus serine:threonine protein kinase 0.0085 0.026 0.026
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0181 0.0767 0.1667
Schistosoma mansoni ephrin receptor 0.0093 0.0306 0.0345
Trypanosoma brucei SNF1-related protein kinases, putative 0.0066 0.0163 0.1657
Schistosoma mansoni cell adhesion molecule 0.0076 0.0217 0.0244
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.018 0.0763 0.1659
Onchocerca volvulus 0.0046 0.0057 0.0066
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0037 0.001 0.001
Echinococcus multilocularis natriuretic peptide receptor 1 0.0046 0.0057 0.0123
Loa Loa (eye worm) TK/ABL protein kinase 0.0238 0.1069 0.1136
Trypanosoma brucei protein kinase, putative 0.0095 0.0317 0.3208
Schistosoma mansoni cell adhesion molecule 0.0058 0.0118 0.0133
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0118 0.0126
Entamoeba histolytica protein kinase domain containing protein 0.015 0.0605 0.4623
Entamoeba histolytica PH domain containing protein kinase, putative 0.0123 0.046 0.3501
Loa Loa (eye worm) hypothetical protein 0.0135 0.0526 0.0559
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0022 0.009
Echinococcus granulosus down syndrome cell adhesion 0.0036 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0224 0.0991 0.1054
Schistosoma mansoni tyrosine kinase 0.0533 0.2621 0.2952
Entamoeba histolytica protein kinase, putative 0.0048 0.0066 0.0433
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0657 0.074
Echinococcus granulosus death domain containing protein 0.0037 0.0011 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0057 0.0235
Loa Loa (eye worm) hypothetical protein 0.0084 0.0256 0.0272
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0698 0.3488 0.3707
Loa Loa (eye worm) TK/INSR protein kinase 0.0366 0.174 0.1849
Schistosoma mansoni cell adhesion molecule 0.0036 0.0003 0.0004
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0046 0.0057 0.0123
Brugia malayi Immunoglobulin I-set domain containing protein 0.0076 0.0217 0.023
Brugia malayi hypothetical protein 0.0085 0.026 0.0277
Brugia malayi Protein kinase domain containing protein 0.0085 0.026 0.0277
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0057 0.0362
Brugia malayi STAT protein, DNA binding domain containing protein 0.0039 0.0019 0.002
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.015 0.0605 0.1314
Trypanosoma brucei NIMA-related protein kinase 0.0038 0.0013 0.0128
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.026 0.0277
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Loa Loa (eye worm) TK/RYK protein kinase 0.0046 0.0057 0.006
Echinococcus granulosus dual specificity protein kinase clk2 0.0114 0.0414 0.0414
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Entamoeba histolytica hypothetical protein 0.0046 0.0057 0.0362
Echinococcus granulosus serine:threonine protein kinase 3 0.019 0.0816 0.0816
Echinococcus multilocularis tyrosine protein kinase Fyn 0.018 0.0763 0.1659
Trichomonas vaginalis AGC family protein kinase 0.0124 0.047 0.1952
Schistosoma mansoni protein kinase 0.0046 0.0057 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0638 0.0718
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0114 0.0414 0.044
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0057 0.0362
Schistosoma mansoni tyrosine kinase 0.0284 0.1308 0.1473
Schistosoma mansoni tyrosine kinase 0.0347 0.1641 0.1848
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0123 0.046 0.0489
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0046 0.0057 0.0362
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus granulosus peroxidasin 0.0077 0.0218 0.0218
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Entamoeba histolytica protein kinase domain containing protein 0.0091 0.0292 0.2188
Brugia malayi Tyrosine-protein kinase abl-1 0.0174 0.073 0.0775
Loa Loa (eye worm) hypothetical protein 0.0076 0.0217 0.023
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Plasmodium vivax protein kinase, putative 0.0057 0.0115 0.2711
Entamoeba histolytica protein kinase domain containing protein 0.0103 0.0357 0.2695
Brugia malayi SH2 domain containing protein 0.0039 0.0019 0.002
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0138 0.0539 0.0573
Giardia lamblia Kinase 0.0046 0.0057 0.0513
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Echinococcus granulosus tyrosine protein kinase Src64B 0.018 0.0763 0.0763
Giardia lamblia Kinase, NEK 0.0046 0.0057 0.0521
Onchocerca volvulus Serine\/threonine kinase homolog 0.0122 0.0455 0.0528
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0869 0.3611
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Schistosoma mansoni GTPase activating protein 0.0039 0.0019 0.0021
Mycobacterium leprae Probable lipase LipE 0.0035 0 0.5
Loa Loa (eye worm) AUR protein kinase 0.0108 0.0382 0.0406
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0455 0.0512
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0014
Brugia malayi protein unc-22 0.0082 0.0247 0.0262
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Trypanosoma cruzi casein kinase, putative 0.008 0.0239 0.2746
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0057 0.0235
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0444 0.2154 0.229
Schistosoma mansoni serine/threonine kinase 0.0161 0.0661 0.0744
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0141 0.0159
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Loa Loa (eye worm) hypothetical protein 0.006 0.0133 0.0141
Echinococcus multilocularis tyrosine protein kinase HCK 0.0111 0.04 0.0868
Leishmania major protein kinase A catalytic subunit isoform 1 0.0084 0.0256 0.2942
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0081 0.0242 0.0525
Echinococcus granulosus tyrosine protein kinase csk 0.0046 0.0057 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.0041 0.0028 0.003
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0046 0.0057 0.0064
Brugia malayi Protein kinase domain containing protein 0.0152 0.0616 0.0655
Brugia malayi Protein kinase domain containing protein 0.0088 0.0278 0.0296
Brugia malayi Homeodomain interacting protein kinase protein 1 0.015 0.0605 0.0643
Brugia malayi Variant SH3 domain containing protein 0.007 0.0182 0.0193
Loa Loa (eye worm) hypothetical protein 0.0039 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0019 0.002
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0039 0.0019 0.0019
Plasmodium falciparum NIMA related kinase 1 0.0101 0.0346 0.8066
Trypanosoma brucei cdc2-related kinase 1 0.0088 0.0278 0.2818
Brugia malayi serine/threonine-protein kinase plk-2 0.02 0.0869 0.0923
Echinococcus granulosus cyclin dependent kinase 1 0.0088 0.0278 0.0278
Echinococcus multilocularis cGMP dependent protein kinase 1 0.01 0.034 0.0738
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0084 0.0256 0.0555
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.008 0.0239 0.0254
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0046 0.0057 0.0123
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Onchocerca volvulus 0.0085 0.026 0.0302
Schistosoma mansoni neuroglian 0.0098 0.0332 0.0374
Loa Loa (eye worm) hypothetical protein 0.0103 0.0356 0.0378
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0003 0.0003
Brugia malayi Egg laying defective protein 4 0.01 0.034 0.0361
Schistosoma mansoni titin 0.0036 0.0003 0.0004
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Loa Loa (eye worm) TK/ALK protein kinase 0.0046 0.0057 0.006
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0091 0.0292 0.031
Echinococcus granulosus expressed protein 0.0062 0.0139 0.0139
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.007 0.0182 0.0205
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Echinococcus granulosus casein kinase I delta 0.008 0.0239 0.0239
Brugia malayi C-terminal src kinase protein 1 0.0046 0.0057 0.006
Entamoeba histolytica protein kinase, putative 0.0046 0.0057 0.0362
Loa Loa (eye worm) hypothetical protein 0.0075 0.0208 0.0221
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0308 0.1279
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Brugia malayi Leucine Rich Repeat family protein 0.0036 0.0004 0.0004
Echinococcus granulosus Immunoglobulin 0.0147 0.0589 0.0589
Schistosoma mansoni tensin 0.0039 0.0019 0.0021
Schistosoma mansoni hypothetical protein 0.0039 0.0019 0.0021
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0062 0.0144 0.0312
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0062 0.0139 0.0148
Echinococcus multilocularis tyrosine protein kinase Srms 0.015 0.0603 0.1311
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0046 0.0057 0.0123
Echinococcus multilocularis serine:threonine protein kinase N2 0.0124 0.047 0.1021
Loa Loa (eye worm) hypothetical protein 0.0103 0.0356 0.0378
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0046 0.0057 0.0066
Entamoeba histolytica protein kinase, putative 0.0037 0.0011 0.0011
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0118 0.0435 0.5011
Schistosoma mansoni tyrosine kinase 0.0193 0.083 0.0934
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0448 0.2173 0.2309
Giardia lamblia Kinase, NEK 0.0046 0.0057 0.0513
Echinococcus granulosus tyrosine protein kinase 0.0224 0.0991 0.0991
Entamoeba histolytica protein kinase domain containing protein 0.0108 0.0382 0.2892
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Giardia lamblia Kinase, CMGC CK2 0.0074 0.0205 0.225
Brugia malayi Protein kinase domain containing protein 0.0085 0.026 0.0277
Loa Loa (eye worm) TK protein kinase 0.0111 0.04 0.0425
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Echinococcus granulosus SH2 motif 0.0039 0.0019 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0292 0.0328
Echinococcus multilocularis 0.0113 0.0412 0.0895
Trypanosoma brucei casein kinase I, isoform 2 0.008 0.0239 0.2418
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0539 0.0607
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Schistosoma mansoni serine/threonine protein kinase 0.022 0.0975 0.1098
Brugia malayi Protein kinase domain containing protein 0.0046 0.0057 0.006
Brugia malayi Protein kinase domain 0.0064 0.015 0.016
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0046 0.0057 0.006
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0066 0.0163 0.0174
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0103 0.0357 0.0379
Loa Loa (eye worm) TK/CSK protein kinase 0.0046 0.0057 0.006
Loa Loa (eye worm) hypothetical protein 0.0058 0.0118 0.0126
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.018 0.0763 0.1659
Plasmodium vivax calcium-dependent protein kinase, putative 0.0075 0.0208 0.4889
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0063 0.0145 0.1049
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0163 0.068
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0869 0.3611
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.01 0.034 0.3569
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0039 0.0019 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0085 0.0264 0.1096
Echinococcus granulosus serine/threonine protein kinase 0.0123 0.046 0.046
Toxoplasma gondii NEK kinase 0.0038 0.0013 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0341 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0845 0.0952
Echinococcus multilocularis cGMP dependent protein kinase 1 0.01 0.034 0.0738
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0039 0.0019 0.004
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0041 0.0028 0.003
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Entamoeba histolytica protein kinase, putative 0.0095 0.0317 0.2383
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0108 0.0382 0.2892
Loa Loa (eye worm) hypothetical protein 0.0037 0.0011 0.0012
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Brugia malayi Immunoglobulin I-set domain containing protein 0.0062 0.0144 0.0153
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0003 0.0003
Onchocerca volvulus 0.0039 0.0019 0.0022
Plasmodium vivax SET domain protein, putative 0.0062 0.0141 0.3322
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0141 0.0159
Brugia malayi Immunoglobulin I-set domain containing protein 0.0076 0.0217 0.023
Schistosoma mansoni hypothetical protein 0.0075 0.0212 0.0239
Echinococcus granulosus cGMP dependent protein kinase 1 0.01 0.034 0.034
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0085 0.0264 0.0573
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0052 0.0091 0.0091
Loa Loa (eye worm) TK/ROR protein kinase 0.0082 0.0245 0.026
Plasmodium falciparum protein kinase, putative 0.007 0.0185 0.4175
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0058 0.0241
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0083 0.0251 0.2885
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0057 0.0362
Giardia lamblia Kinase, NEK 0.0101 0.0346 0.3891
Brugia malayi Prion-like- 0.0036 0.0003 0.0003
Schistosoma mansoni cell adhesion molecule 0.021 0.0918 0.1034
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Entamoeba histolytica hypothetical protein 0.0046 0.0057 0.0362
Brugia malayi serine/threonine-protein kinase 6 0.0108 0.0382 0.0406
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0122 0.0455 0.0483
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0036 0.0003 0.0007
Brugia malayi Protein kinase domain containing protein 0.0161 0.0661 0.0702
Leishmania major casein kinase II, putative 0.0074 0.0205 0.2362
Trichomonas vaginalis STE family protein kinase 0.0048 0.0066 0.0273
Onchocerca volvulus 0.1589 0.8179 0.9501
Echinococcus granulosus suppressor of cytokine signaling 6 0.0039 0.0019 0.0019
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0057 0.0362
Loa Loa (eye worm) TK/EPH protein kinase 0.0106 0.0375 0.0398
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0341 0.0384
Loa Loa (eye worm) hypothetical protein 0.0039 0.0019 0.002
Schistosoma mansoni nephrin 0.0098 0.0332 0.0374
Brugia malayi Hr1 repeat family protein 0.022 0.0975 0.1037
Echinococcus multilocularis FL cytokine receptor 0.0046 0.0057 0.0123
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.0165 0.0685
Loa Loa (eye worm) hypothetical protein 0.0147 0.0589 0.0626
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0278 0.0313
Trichomonas vaginalis STE family protein kinase 0.0064 0.015 0.0625
Onchocerca volvulus 0.0085 0.026 0.0302
Loa Loa (eye worm) AGC/PKA protein kinase 0.0084 0.0256 0.0272
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0141 0.0159
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0261 0.119 0.1264
Echinococcus granulosus c-Jun N-terminal kinases 0.0196 0.0845 0.0845
Entamoeba histolytica receptor protein kinase, putative 0.0046 0.0057 0.0362
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0062 0.0139 0.1459
Brugia malayi Immunoglobulin I-set domain containing protein 0.0229 0.1018 0.1082
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0161 0.0661 0.0702
Trypanosoma cruzi cdc2-related kinase 1 0.0088 0.0278 0.3201
Entamoeba histolytica protein kinase, putative 0.0064 0.015 0.109
Loa Loa (eye worm) hypothetical protein 0.0188 0.0803 0.0853
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0083 0.0251 0.0282
Schistosoma mansoni tyrosine protein kinase 0.0046 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0064 0.015 0.0159
Entamoeba histolytica hypothetical protein 0.0046 0.0057 0.0368
Giardia lamblia Kinase, STE STE20 0.0063 0.0145 0.1546
Loa Loa (eye worm) DOMON domain-containing protein 0.0174 0.0731 0.0777
Giardia lamblia Protein 21.1 0.0046 0.0057 0.0513
Loa Loa (eye worm) hypothetical protein 0.0083 0.0251 0.0266
Loa Loa (eye worm) hypothetical protein 0.0062 0.0141 0.015
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0039 0.0019 0.002
Leishmania major protein kinase, putative 0.0046 0.0057 0.0651
Plasmodium falciparum protein kinase, putative 0.0046 0.0057 0.1063
Entamoeba histolytica PH domain containing protein kinase, putative 0.0123 0.046 0.3501
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0185 0.0791 0.0791
Loa Loa (eye worm) disorganized muscle protein 1 0.0036 0.0003 0.0003
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0041 0.0028 0.0032
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0057 0.0235
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0149 0.0598 0.0635
Trichomonas vaginalis AGC family protein kinase 0.0223 0.0987 0.4102
Echinococcus granulosus activin receptor type 0.007 0.0185 0.0185
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0165 0.0681 0.0681
Trypanosoma brucei aurora B kinase 0.0108 0.0382 0.3873
Schistosoma mansoni protein kinase 0.0046 0.0057 0.0064
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.026 0.0277
Loa Loa (eye worm) casein kinase 0.0134 0.0518 0.055
Echinococcus multilocularis SH2 motif 0.0039 0.0019 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0646 0.0728
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0036 0.0003 0.0003
Plasmodium vivax casein kinase 1, putative 0.008 0.0239 0.5605
Brugia malayi Protein kinase domain containing protein 0.0272 0.1245 0.1323
Onchocerca volvulus 0.0046 0.0057 0.0066
Loa Loa (eye worm) TK/DDR protein kinase 0.0046 0.0057 0.006
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0124 0.047 0.047
Schistosoma mansoni tyrosine kinase 0.0046 0.0057 0.0064
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0205 0.0231
Entamoeba histolytica hypothetical protein 0.0282 0.1297 1
Onchocerca volvulus 0.0039 0.0019 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0028 0.0031
Brugia malayi Tensin 0.0039 0.0019 0.002
Onchocerca volvulus 0.0492 0.2406 0.2795
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0076 0.0217 0.023

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.06 uM Vascular endothelial growth factor receptor 2 inhibitory activity at 2 uM of ATP in vitro. ChEMBL. 10639280
IC50 (binding) = 0.06 uM Vascular endothelial growth factor receptor 2 inhibitory activity at 2 uM of ATP in vitro. ChEMBL. 10639280
IC50 (binding) = 0.9 uM In vitro vascular endothelial growth factor receptor 1 inhibitory activity at 2 uM of ATP. ChEMBL. 10639280
IC50 (binding) = 0.9 uM In vitro vascular endothelial growth factor receptor 1 inhibitory activity at 2 uM of ATP. ChEMBL. 10639280
IC50 (binding) > 100 uM FGFR-1 (FTK) inhibitory activity at 2 uM of ATP in vitro. ChEMBL. 10639280
IC50 (binding) > 100 uM FGFR-1 (FTK) inhibitory activity at 2 uM of ATP in vitro. ChEMBL. 10639280
Selectivity (binding) > 100 Ratio of IC50 of FGFR-1 (FTK) to VEGFR-1 (Flt). ChEMBL. 10639280
Selectivity (binding) > 1600 Ratio of IC50 of FGFR-1 (FTK) to VEGFR-2 (KDR). ChEMBL. 10639280

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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