Detailed information for compound 281247

Basic information

Technical information
  • TDR Targets ID: 281247
  • Name: 1-(6,7-dimethylnaphthalen-1-yl)-2-imidazol-1- ylethanone
  • MW: 264.322 | Formula: C17H16N2O
  • H donors: 0 H acceptors: 2 LogP: 3.5 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1cccc2c1cc(C)c(c2)C)Cn1cncc1
  • InChi: 1S/C17H16N2O/c1-12-8-14-4-3-5-15(16(14)9-13(12)2)17(20)10-19-7-6-18-11-19/h3-9,11H,10H2,1-2H3
  • InChiKey: ODLIXGTZZCULEZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(6,7-dimethyl-1-naphthyl)-2-imidazol-1-yl-ethanone
  • 1-(6,7-dimethyl-1-naphthyl)-2-(1-imidazolyl)ethanone
  • 1-(6,7-dimethylnaphthalen-1-yl)-2-imidazol-1-yl-ethanone

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans lipase LipD 0.0048 0.0145 0.0344
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.003 0.0048
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0014 0.0018
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0015 0.0014 0.0009
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) norepinephrine transporter 0.0061 0.0199 0.051
Echinococcus granulosus smad 0.0043 0.0126 0.0205
Schistosoma mansoni hypothetical protein 0.0095 0.0335 0.055
Echinococcus multilocularis microtubule associated protein 2 0.1535 0.6093 0.6093
Echinococcus granulosus caspase 0.002 0.0034 0.0054
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.065 0.2554 1
Trichomonas vaginalis abcb9, putative 0.0024 0.0049 0.0189
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0035 0.0094 0.0794
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0034 0.0059
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0029 0.0366
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0061 0.0128
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0094 0.0154
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0035 0.0094 0.0124
Schistosoma mansoni hypothetical protein 0.0016 0.0019 0.0031
Brugia malayi conserved hypotetical protein 0.003 0.0074 0.0188
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0111 0.0147
Plasmodium vivax metacaspase 1, putative 0.002 0.0034 0.042
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.0031 0.0077
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0318 0.1224 0.3095
Echinococcus multilocularis apoptotic protease activating factor 1 0.0046 0.0139 0.0138
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.002 0.0034 0.0054
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.012 0.0279
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0034 0.0129
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0493 0.0655
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0209 0.0208
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0064 0.0208 0.0533
Loa Loa (eye worm) hypothetical protein 0.0064 0.0208 0.0533
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0049 0.0189
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0025 0.0056 0.0091
Leishmania major cathepsin L-like protease 0.0135 0.0493 0.0655
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0014 0.0018
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0067 0.0089
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0715 0.2797
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0004 0.0012
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0027 0.0035
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0074 0.0164
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0025 0.0056 0.0091
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0096 0.0095
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0086 0.0296 0.2521
Loa Loa (eye worm) hypothetical protein 0.0034 0.0089 0.0225
Brugia malayi SPARC precursor 0.0086 0.0296 0.0759
Loa Loa (eye worm) nuclear receptor nhr-7B 0.003 0.0074 0.0188
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0064 0.0208 0.0533
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Onchocerca volvulus Putative organic anion transporter 0.0125 0.0455 0.1144
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0096 0.0244
Brugia malayi hypothetical protein 0.0064 0.0209 0.0535
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.012 0.0467
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0044 0.0167
Echinococcus multilocularis Protein lozenge 0.0124 0.0449 0.0448
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.005 0.0153 0.0152
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.0037 0.0102 0.0862
Schistosoma mansoni sodium/chloride dependent transporter 0.0061 0.0199 0.0327
Schistosoma mansoni hypothetical protein 0.0095 0.0335 0.055
Entamoeba histolytica cysteine protease, putative 0.0018 0.0027 0.0103
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0188
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0034 0.0044
Loa Loa (eye worm) retinol dehydrogenase 12 0.0014 0.0011 0.0025
Entamoeba histolytica cysteine protease, putative 0.0018 0.0027 0.0103
Onchocerca volvulus 0.0125 0.0455 0.1144
Brugia malayi Uncoordinated protein 44 0.0016 0.0019 0.0046
Schistosoma mansoni survival motor neuron protein 0.0054 0.0171 0.028
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0025 0.0056 0.0074
Onchocerca volvulus 0.0035 0.0096 0.0219
Entamoeba histolytica hypothetical protein 0.0072 0.0241 0.0942
Loa Loa (eye worm) glutaminase 0.0307 0.1182 0.3033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0493 0.0655
Schistosoma mansoni nuclear receptor nhr-48 0.003 0.0074 0.0122
Brugia malayi jmjC domain containing protein 0.0035 0.0094 0.0239
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0061 0.008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0239
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0034 0.0044
Echinococcus granulosus snurportin 1 0.0169 0.0629 0.1031
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0086 0.0296 0.0759
Loa Loa (eye worm) CXXC zinc finger family protein 0.0064 0.021 0.0537
Brugia malayi secreted modular calcium-binding protein 1 0.0086 0.0296 0.0759
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0035 0.0133
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0035 0.0133
Brugia malayi hypothetical protein 0.0125 0.0455 0.1167
Echinococcus multilocularis SAM and MBT domain containing protein 0.0037 0.0102 0.0101
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0027 0.0103
Treponema pallidum sodium- and chloride- dependent transporter 0.0061 0.0199 0.0672
Trypanosoma brucei importin beta-1 subunit, putative 0.0016 0.0018 0.0022
Brugia malayi beta-lactamase family protein 0.0048 0.0145 0.0371
Brugia malayi Cytochrome P450 family protein 0.0033 0.0088 0.0224
Echinococcus multilocularis transcription factor btf3 0.0039 0.0111 0.011
Schistosoma mansoni Smad4 0.0019 0.0031 0.0051
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0017 0.0023 0.0033
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0086 0.0296 0.0759
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.0031 0.0049
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0015 0.0014 0.0009
Brugia malayi GMP synthase 0.0037 0.0102 0.0259
Loa Loa (eye worm) hypothetical protein 0.0086 0.0296 0.0759
Loa Loa (eye worm) hypothetical protein 0.0077 0.0261 0.0668
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0015 0.0014 0.0009
Leishmania major fk506-binding protein 1-like protein 0.0025 0.0056 0.0074
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0012 0.0001 0.0001
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0115 0.0414 0.068
Schistosoma mansoni phosphatidylserine receptor 0.0035 0.0094 0.0154
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0209 0.0342
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0096 0.0527
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0715 0.2797
Brugia malayi Muscleblind-like protein 0.0332 0.1283 0.3293
Loa Loa (eye worm) matrixin family protein 0.019 0.0713 0.183
Loa Loa (eye worm) RNA binding protein 0.0071 0.0239 0.0611
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.034 0.0872
Trypanosoma cruzi importin beta-1 subunit, putative 0.0013 0.0006 0.0006
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0088 0.0116
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0208 0.0785 0.4331
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0115 0.0414 0.0413
Entamoeba histolytica NAD synthetase, putative 0.0092 0.0323 0.1262
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.029 0.1114 0.2859
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0012 0.0045
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.002 0.0034 0.0085
Trichomonas vaginalis glutaminase, putative 0.0307 0.1182 0.4625
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0145 0.1844
Onchocerca volvulus 0.0035 0.0096 0.0219
Onchocerca volvulus 0.0035 0.0096 0.0219
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0022 0.0044 0.0057
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.012 0.0159
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.029 0.1114 0.2859
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0037
Onchocerca volvulus Cell death protein 3 homolog 0.0066 0.0219 0.0536
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0088 0.0224
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0079 0.0268 0.044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0002 0.0006
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0014 0.0011 0.0125
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0014 0.0011 0.0025
Echinococcus multilocularis muscleblind protein 0.0332 0.1283 0.1282
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.034 0.0557
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0266 0.1016 0.1353
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0088 0.0224
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0022 0.0044 0.0167
Entamoeba histolytica hypothetical protein 0.0013 0.0006 0.0019
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0029 0.0048
Mycobacterium tuberculosis Probable lipase LipD 0.0048 0.0145 0.0344
Echinococcus multilocularis beta LACTamase domain containing family member 0.0048 0.0145 0.0145
Echinococcus granulosus survival motor neuron protein 1 0.0266 0.1016 0.1666
Trichomonas vaginalis hypothetical protein 0.0208 0.0785 0.3072
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0305 0.1175 0.297
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.003 0.0074 0.012
Loa Loa (eye worm) multidrug resistance protein 3 0.0024 0.0049 0.0124
Schistosoma mansoni dihydropteridine reductase 0.0014 0.0011 0.0017
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0017 0.0023 0.0033
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0241 0.0396
Schistosoma mansoni hypothetical protein 0.0046 0.0139 0.0229
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0085
Loa Loa (eye worm) serotonin transporter b 0.0061 0.0199 0.051
Mycobacterium leprae conserved hypothetical protein 0.0048 0.0145 0.0754
Schistosoma mansoni hypothetical protein 0.0206 0.0778 0.1276
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0067 0.0371
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0015 0.0014 0.0009
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0049 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0493 0.0655
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0061 0.0235
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0094 0.0795
Leishmania major basic transcription factor 3a, putative 0.0039 0.0111 0.0147
Plasmodium falciparum JmjC domain-containing protein, putative 0.0035 0.0094 0.0517
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0029 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0111 0.0433
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0094 0.0154
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0096 0.0371
Entamoeba histolytica cysteine protease, putative 0.0018 0.0027 0.0103
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0038 0.0096
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.0493 0.0655
Schistosoma mansoni nuclear receptor 0.003 0.0074 0.0122
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0096 0.0371
Brugia malayi hypothetical protein 0.0034 0.0089 0.0225
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0044 0.0167
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0113 0.0408 0.0542
Onchocerca volvulus 0.0048 0.0145 0.0347
Onchocerca volvulus Matrix metalloproteinase homolog 0.0174 0.065 0.1648
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0715 0.2797
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0096 0.0095
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0019 0.0031 0.0052
Trichomonas vaginalis D-aminoacylase, putative 0.0048 0.0145 0.0566
Trypanosoma cruzi major cysteine proteinase, putative 0.0106 0.0378 0.0502
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0034 0.0089 0.0144
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0014 0.0011 0.0016
Schistosoma mansoni inositol monophosphatase 0.0041 0.012 0.0197
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0005 0.0004
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0064 0.0208 0.0342
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0025 0.0056 0.0074
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0208 0.0785 0.4331
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0049 0.0048
Trichomonas vaginalis glucosylceramidase, putative 0.0201 0.0756 0.2958
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0025 0.0056 0.0216
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.0092 0.0323 0.4109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0003 0.0007
Schistosoma mansoni inositol monophosphatase 0.0041 0.012 0.0197
Toxoplasma gondii exonuclease III APE 0.0019 0.0029 0.0245
Schistosoma mansoni ap endonuclease 0.0019 0.0029 0.0048
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0055 0.0176 0.0288
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.034 0.0559
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0301 0.1159 0.2973
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0034 0.0129
Schistosoma mansoni ran 0.0012 0.0001 0.0001
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0049 0.0189
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0105 0.0375 0.0615
Schistosoma mansoni caspase-3 (C14 family) 0.002 0.0034 0.0055
Plasmodium vivax multidomain scavenger receptor, putative 0.0064 0.0209 0.2657
Onchocerca volvulus Matrilysin homolog 0.0079 0.0268 0.0663
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0019 0.0032 0.0055
Schistosoma mansoni caspase-7 (C14 family) 0.0066 0.0219 0.0359
Brugia malayi Cathepsin L-like precursor 0.0024 0.0049 0.0124
Loa Loa (eye worm) hypothetical protein 0.0102 0.0363 0.0931
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0031 0.0077
Brugia malayi Death domain containing protein 0.0016 0.0019 0.0046
Schistosoma mansoni nuclear hormone receptor 0.003 0.0074 0.0122
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1114 0.4359
Echinococcus granulosus lysine specific demethylase 6a 0.0035 0.0094 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Schistosoma mansoni chromobox protein 0.0035 0.0093 0.0152
Schistosoma mansoni cpg binding protein 0.0068 0.0224 0.0368
Loa Loa (eye worm) hypothetical protein 0.0125 0.0455 0.1167
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0074 0.012
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0208 0.0785 0.6694
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0027 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0025 0.0096
Leishmania major peptidylprolyl isomerase-like protein 0.0025 0.0056 0.0074
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.0027 0.0146
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.0461 0.1799 0.456
Onchocerca volvulus 0.0048 0.0145 0.0347
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0014 0.0018
Brugia malayi sodium-independent organic anion transporter family protein 0.0125 0.0455 0.1167
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0064 0.0208 0.0341
Plasmodium falciparum metacaspase 1 0.002 0.0034 0.0183
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0096 0.0244
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1889 0.7507 1
Echinococcus granulosus tar DNA binding protein 0.0071 0.0239 0.0391
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0015 0.0014 0.0009
Echinococcus multilocularis RUN 0.0064 0.0209 0.0208
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0208 0.0785 0.1975
Echinococcus granulosus nuclear receptor nhr 48 0.003 0.0074 0.012
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0093 0.036
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0115 0.0414 0.068
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0131 0.0477 0.0477
Schistosoma mansoni zinc finger protein 0.003 0.0074 0.0122
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.012 0.0467
Echinococcus granulosus histone acetyltransferase MYST2 0.0042 0.0122 0.0199
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0894 0.3529 0.47
Trypanosoma brucei Metacaspase-4 0.002 0.0034 0.0044
Onchocerca volvulus Putative organic anion transporter 0.0125 0.0455 0.1144
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0061 0.0128
Brugia malayi jmjC domain containing protein 0.0035 0.0094 0.0239
Entamoeba histolytica cysteine protease, putative 0.0018 0.0027 0.0103
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.034 0.0872
Onchocerca volvulus 0.0048 0.0145 0.0347
Brugia malayi hypothetical protein 0.0125 0.0455 0.1167
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0015 0.0014 0.0009
Plasmodium vivax hypothetical protein, conserved 0.002 0.0034 0.042
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0086 0.0296 0.2521
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.0092 0.0323 0.0797
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0094 0.0239
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0064 0.0208 0.0533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0044 0.0167
Onchocerca volvulus 0.0017 0.0023 0.0033
Loa Loa (eye worm) nuclear factor I 0.0024 0.0049 0.0124
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0094 0.0093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0096 0.0371
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0007 0.0025
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0086 0.0296 0.2521
Echinococcus multilocularis follistatin 0.0086 0.0296 0.0295
Echinococcus granulosus transcription factor btf3 0.0039 0.0111 0.0181
Brugia malayi Cathepsin L-like precursor 0.0035 0.0096 0.0244
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0034 0.0129
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Brugia malayi hypothetical protein 0.0018 0.0027 0.0068
Brugia malayi jmjC domain containing protein 0.0035 0.0094 0.0239
Onchocerca volvulus 0.0041 0.0117 0.0273
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0113 0.0408 0.1045
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0324 0.1249 0.1662
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0715 0.2797
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0096 0.0371
Mycobacterium ulcerans NAD synthetase 0.0092 0.0323 0.0797
Loa Loa (eye worm) hypothetical protein 0.0095 0.0335 0.0859
Leishmania major cytochrome p450-like protein 0.0015 0.0014 0.0018
Echinococcus granulosus adam 17 protease 0.0116 0.0417 0.0683
Loa Loa (eye worm) hypothetical protein 0.0079 0.0268 0.0687
Mycobacterium tuberculosis Conserved protein 0.0048 0.0145 0.0344
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0022 0.0044 0.0057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0027 0.0035
Loa Loa (eye worm) latrophilin receptor protein 2 0.0095 0.0335 0.0859
Loa Loa (eye worm) hypothetical protein 0.0061 0.0199 0.051
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0027 0.0103
Brugia malayi hypothetical protein 0.0102 0.0363 0.0931
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0064 0.0208 0.0533
Schistosoma mansoni nuclear hormone receptor 0.0064 0.0208 0.0342
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0049 0.0189
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0209 0.0342
Trichomonas vaginalis fk506-binding protein, putative 0.0025 0.0056 0.0216
Echinococcus granulosus cathepsin l1 0.0035 0.0096 0.0156
Mycobacterium ulcerans hypothetical protein 0.0995 0.3933 1
Echinococcus granulosus Solute carrier organic anion transporter family 0.0125 0.0455 0.0746
Mycobacterium leprae PROBABLE HYDROLASE 0.0096 0.0337 0.1823
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0049 0.0189
Trypanosoma cruzi metacaspase, putative 0.002 0.0034 0.0044
Schistosoma mansoni ran 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0086 0.0296 0.0759
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0115 0.0414 0.068
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0241 0.024
Echinococcus granulosus cysteine protease 0.0018 0.0027 0.0043
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0038 0.0037
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0015 0.0014 0.0009
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0019 0.003
Mycobacterium tuberculosis Probable hydrolase 0.0048 0.0145 0.0344
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0169 0.0629 0.1613
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0061 0.0235
Schistosoma mansoni hypothetical protein 0.0252 0.0963 0.1581
Echinococcus multilocularis polycomb protein SCMH1 0.0037 0.0102 0.0101
Loa Loa (eye worm) MH2 domain-containing protein 0.0043 0.0126 0.032
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0037 0.0094
Brugia malayi chromobox protein homolog 3 0.0019 0.0032 0.008
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0063 0.0205 0.0205
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0117 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0008 0.0027
Echinococcus multilocularis Ankyrin 0.0016 0.0019 0.0019
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.0037 0.0102 0.0166
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0049 0.0189
Leishmania major cathepsin L-like protease 0.0035 0.0096 0.0126
Schistosoma mansoni myelin transcription factor 1 myt1 0.0042 0.0122 0.02
Brugia malayi Nuclear hormone receptor E75 0.003 0.0074 0.0188
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.0092 0.0323 0.1792
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0061 0.0128
Schistosoma mansoni hypothetical protein 0.0252 0.0963 0.1581
Entamoeba histolytica cysteine protease, putative 0.0035 0.0096 0.0371
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0096 0.0527
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.003 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0002 0.0006
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0064 0.0208 0.0208
Echinococcus multilocularis lysine specific demethylase 5A 0.0131 0.0477 0.0477
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0493 0.0655
Schistosoma mansoni multidrug resistance protein 0.0024 0.0049 0.008
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0049 0.0189
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0048 0.0145 0.0239
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0029 0.0038
Brugia malayi photoreceptor-specific nuclear receptor 0.0064 0.0208 0.0533
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0034 0.0129
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0048 0.0145 0.0371
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0096 0.0095
Leishmania major cytochrome p450-like protein 0.0033 0.0088 0.0116
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0025 0.0056 0.0142
Loa Loa (eye worm) hypothetical protein 0.0125 0.0455 0.1167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Echinococcus granulosus Ankyrin 0.0016 0.0019 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0021 0.0078
Echinococcus granulosus GPCR family 2 0.0095 0.0335 0.0549
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0088 0.0197
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0095 0.0335 0.0549
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0023 0.0036
Trypanosoma cruzi NAD+ synthase, putative 0.0092 0.0323 0.0429
Echinococcus multilocularis adam 17 protease 0.0105 0.0375 0.0374
Toxoplasma gondii protease inhibitor PI2 0.0086 0.0296 0.2521
Brugia malayi hypothetical protein 0.0064 0.0209 0.0535
Mycobacterium ulcerans beta-lactamase 0.0048 0.0145 0.0344
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0027 0.0103
Onchocerca volvulus 0.0111 0.0399 0.1001
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.0461 0.1799 0.7009
Brugia malayi MH1 domain containing protein 0.0024 0.0049 0.0124
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0039 0.0108 0.0177
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0113 0.0408 0.0542
Schistosoma mansoni hypothetical protein 0.0013 0.0005 0.0008
Brugia malayi beta-NAC-like protein 0.0039 0.0111 0.0284
Trichomonas vaginalis penicillin-binding protein, putative 0.0048 0.0145 0.0566
Echinococcus granulosus Smad4 0.0043 0.0126 0.0205
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0061 0.0128
Brugia malayi glutaminase DH11.1 0.0307 0.1182 0.3033
Echinococcus granulosus beta LACTamase domain containing family member 0.0048 0.0145 0.0237
Loa Loa (eye worm) RecQ helicase 0.0024 0.0049 0.0124
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0025 0.0056 0.0074
Brugia malayi sodium-independent organic anion transporter family protein 0.0125 0.0455 0.1167
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0131 0.0477 0.0782
Entamoeba histolytica P-glycoprotein-1 0.0024 0.0049 0.0189
Brugia malayi nuclear hormone receptor family member odr-7 0.003 0.0074 0.0188
Brugia malayi latrophilin 2 splice variant baaae 0.0206 0.0778 0.1995
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0096 0.0371
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.007
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.0493 0.0655
Trypanosoma cruzi metacaspase, putative 0.002 0.0034 0.0044
Mycobacterium ulcerans short chain dehydrogenase 0.0017 0.0023 0.0033
Echinococcus granulosus serotonin transporter 0.0061 0.0199 0.0326
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0064 0.0208 0.0342
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0096 0.0244
Plasmodium vivax basic transcription factor 3b, putative 0.0039 0.0111 0.1409
Entamoeba histolytica cysteine proteinase 2 0.0018 0.0027 0.0103
Brugia malayi hypothetical protein 0.0034 0.0089 0.0225
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0096 0.0095
Onchocerca volvulus Huntingtin homolog 0.0102 0.0363 0.0909
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0049 0.0189
Entamoeba histolytica cysteine protease, putative 0.0018 0.0027 0.0103
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0067 0.0089
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0074 0.012
Brugia malayi Pre-SET motif family protein 0.0035 0.0094 0.0239
Onchocerca volvulus 0.0064 0.0208 0.0509
Leishmania major NAD synthase, putative 0.0092 0.0323 0.0429
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0064 0.0208 0.0533
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0061 0.0154
Loa Loa (eye worm) hypothetical protein 0.0125 0.0455 0.1167
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0061 0.008
Brugia malayi Cytochrome P450 family protein 0.0055 0.0175 0.0448
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0111 0.0433
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0025 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0033
Mycobacterium ulcerans hypothetical protein 0.0048 0.0145 0.0344
Schistosoma mansoni smad 0.0019 0.0031 0.0051
Entamoeba histolytica P-glycoprotein-5 0.0024 0.0049 0.0189
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0064 0.0208 0.0342
Plasmodium falciparum LCCL domain-containing protein 0.0064 0.0209 0.1159
Brugia malayi MH1 domain containing protein 0.0043 0.0126 0.032
Loa Loa (eye worm) hypothetical protein 0.0034 0.0089 0.0225
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0032 0.0122
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0034 0.0421
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0012 0.0045
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0048 0.0145 0.0344
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0044 0.011
Trypanosoma brucei metacaspase 0.002 0.0034 0.0044
Mycobacterium leprae putative cytochrome p450 0.0015 0.0014 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0034 0.0129
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0088 0.0116
Brugia malayi Inositol-1 0.0041 0.012 0.0306
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0085
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0018 0.0225
Schistosoma mansoni smad1 5 8 and 0.0043 0.0126 0.0206
Brugia malayi cytochrome P450 0.0015 0.0014 0.0034
Leishmania major cathepsin L-like protease 0.0035 0.0096 0.0126
Brugia malayi orphan nuclear receptor NR2E1 0.003 0.0074 0.0188
Echinococcus multilocularis tar DNA binding protein 0.0071 0.0239 0.0238
Echinococcus multilocularis histone acetyltransferase MYST2 0.0042 0.0122 0.0121
Loa Loa (eye worm) hypothetical protein 0.0042 0.0122 0.0311
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0188
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0188
Leishmania major hypothetical protein, conserved 0.0035 0.0094 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0145 0.0193
Entamoeba histolytica cysteine protease, putative 0.0018 0.0027 0.0103
Onchocerca volvulus 0.0086 0.0296 0.0735
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.034 0.0559
Schistosoma mansoni immunophilin 0.0025 0.0056 0.0092
Schistosoma mansoni thyroid hormone receptor 0.0126 0.0459 0.0754
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0064 0.0208 0.0341
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0022 0.0044 0.0043
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0022 0.0044 0.0057
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.0461 0.1799 1
Trypanosoma cruzi metacaspase, putative 0.002 0.0034 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0096 0.0371
Plasmodium vivax unspecified product 0.0012 0.0001 0.0003
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0014 0.0011 0.0083
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0034 0.0184
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0049 0.0189
Leishmania major p-glycoprotein 0.0024 0.0049 0.0064
Loa Loa (eye worm) hypothetical protein 0.0986 0.3894 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0023 0.0037
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0103 0.0515
Loa Loa (eye worm) cytochrome P450 0.0015 0.0014 0.0034
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0074 0.012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0493 0.0655
Brugia malayi hypothetical protein 0.0072 0.0241 0.0618
Brugia malayi Cathepsin L-like precursor 0.0035 0.0096 0.0244
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0239 0.0392
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0061 0.0199 0.0327
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0005 0.0007
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.0493 0.0655
Brugia malayi tailless protein 0.003 0.0074 0.0188
Schistosoma mansoni cytochrome P450 0.0015 0.0014 0.0023
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.065 0.2554 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0096 0.0527
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0035 0.0094 0.0124
Brugia malayi Smad1 0.0043 0.0126 0.032
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0025 0.0056 0.0074
Loa Loa (eye worm) hypothetical protein 0.0034 0.0089 0.0225
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0029 0.0038
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0043 0.0126 0.0206
Loa Loa (eye worm) hypothetical protein 0.0206 0.0778 0.1995
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0003 0.0007
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0049 0.0189
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0095 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0064 0.0208 0.0533
Plasmodium vivax SET domain protein, putative 0.0035 0.0094 0.1187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0002 0.0006
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0067 0.0089
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0096 0.0126
Schistosoma mansoni retinoic acid receptor RXR 0.0174 0.0651 0.1068
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0049 0.0189
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.0037 0.0102 0.0101
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0015 0.0014 0.0009
Loa Loa (eye worm) hypothetical protein 0.0064 0.0209 0.0535
Leishmania major cathepsin L-like protease 0.0035 0.0096 0.0126
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0064 0.0208 0.0533
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.003 0.0074 0.0122
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0029 0.0159
Loa Loa (eye worm) inositol-1 0.0041 0.012 0.0306
Entamoeba histolytica cysteine protease, putative 0.0018 0.0027 0.0103
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0067 0.0569
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0008 0.0028
Trichomonas vaginalis importin beta-1, putative 0.0013 0.0006 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0015 0.0014 0.0009
Leishmania major mitochondrial DNA polymerase beta 0.1889 0.7507 1
Brugia malayi MH2 domain containing protein 0.0019 0.0031 0.0077
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0049 0.0189
Onchocerca volvulus 0.0035 0.0096 0.0219
Leishmania major importin beta-1 subunit, putative 0.0013 0.0006 0.0006
Onchocerca volvulus 0.0024 0.0049 0.0099
Trypanosoma cruzi NAD+ synthase, putative 0.0092 0.0323 0.0429
Giardia lamblia GTOR 0.0022 0.0044 0.0167
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0096 0.0371
Echinococcus granulosus mitogen activated protein kinase 3 0.0113 0.0408 0.0668
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.012 0.0119
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0049 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Entamoeba histolytica transcription factor BTF3, putative 0.0039 0.0111 0.0433
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0025 0.0056 0.0074
Leishmania major hypothetical protein, conserved 0.0048 0.0145 0.0193
Brugia malayi Nuclear hormone receptor E75 0.003 0.0074 0.0188
Giardia lamblia Kinase, CMGC MAPK 0.0113 0.0408 0.1593
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0094 0.0239
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0023 0.0036
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0027 0.0035
Trypanosoma brucei NAD+ synthase, putative 0.0092 0.0323 0.0429
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0024 0.0049 0.0124
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0015 0.0014 0.0009
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0029 0.0048
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0042 0.0122 0.0311
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0125 0.0455 0.0454
Entamoeba histolytica hypothetical protein 0.0072 0.0241 0.0942
Echinococcus granulosus lysine specific demethylase 5A 0.0135 0.0492 0.0806
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0188
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0013 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0221 0.0838 0.2151
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0318 0.1224 0.3095
Giardia lamblia NH3-dependent NAD+ synthetase 0.0092 0.0323 0.1262
Brugia malayi Pre-SET motif family protein 0.0235 0.0894 0.2295
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0115 0.0414 0.0413
Loa Loa (eye worm) oxidoreductase 0.0014 0.0011 0.0025
Schistosoma mansoni hypothetical protein 0.0111 0.0399 0.0655
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0111 0.0147
Mycobacterium leprae Conserved hypothetical protein 0.0015 0.0014 0.0019
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0015 0.0014 0.0009
Brugia malayi Matrixin family protein 0.019 0.0713 0.183
Schistosoma mansoni glutaminase 0.0307 0.1182 0.1939
Loa Loa (eye worm) hypothetical protein 0.0086 0.0296 0.0759
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0064 0.0208 0.0533
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0025 0.0056 0.0216
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0018 0.0144
Echinococcus granulosus JmjC domain containing protein 4 0.0035 0.0094 0.0153
Loa Loa (eye worm) hypothetical protein 0.0079 0.0268 0.0687
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1114 0.4359
Brugia malayi steroid hormone receptor 0.0064 0.0208 0.0533
Toxoplasma gondii ABC1 family protein 0.0048 0.0145 0.1234
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0015 0.0014 0.0009
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0048 0.0145 0.0344
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0027 0.0045
Echinococcus multilocularis lysine specific demethylase 6a 0.0035 0.0094 0.0093
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0015 0.0014 0.0009
Brugia malayi Cathepsin L-like precursor 0.0035 0.0096 0.0244
Schistosoma mansoni follistatin 0.0086 0.0296 0.0486
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0029 0.0074
Loa Loa (eye worm) hypothetical protein 0.0061 0.0199 0.051
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0074 0.0073
Schistosoma mansoni RAR-like nuclear receptor 0.0064 0.0208 0.0342
Echinococcus granulosus multidrug resistance protein 1 0.0017 0.002 0.0032
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0064 0.0208 0.0342
Echinococcus granulosus phd:f box containing protein 0.0035 0.0094 0.0153
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0085
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0061 0.0128
Schistosoma mansoni rab6-interacting 0.0064 0.0209 0.0343
Trichomonas vaginalis esterase, putative 0.0048 0.0145 0.0566
Entamoeba histolytica P-glycoprotein-2 0.0024 0.0049 0.0189
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0064 0.0208 0.0533
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0015 0.0014 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0239 0.0392
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0285 0.1096 0.1095
Loa Loa (eye worm) hypothetical protein 0.0061 0.0199 0.051
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0049 0.0189
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0095 0.0335 0.0335
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Onchocerca volvulus 0.0046 0.0139 0.0331
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0064 0.0208 0.0342
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0017 0.0023 0.0033
Schistosoma mansoni transcription factor btf3 0.0039 0.0111 0.0183
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0096 0.0157
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.065 0.2554 1
Plasmodium vivax vivapain-1 0.0018 0.0027 0.0335
Entamoeba histolytica cysteine protease, putative 0.0018 0.0027 0.0103
Loa Loa (eye worm) nuclear hormone receptor 0.003 0.0074 0.0188
Echinococcus multilocularis GPCR, family 2 0.0095 0.0335 0.0335
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.034 0.0557
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0066 0.0218 0.0217
Entamoeba histolytica cysteine protease, putative 0.0018 0.0027 0.0103
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0014 0.0011 0.0083
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0012 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0012 0.0045
Loa Loa (eye worm) hypothetical protein 0.0024 0.0049 0.0124
Schistosoma mansoni organic anion transporter 0.0125 0.0455 0.0747
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0096 0.0156
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0049 0.0079
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0049 0.0189
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1114 0.4359
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0015 0.0014 0.0009
Loa Loa (eye worm) DR-78 0.003 0.0074 0.0188
Leishmania major oxidoreductase-like protein 0.0017 0.0023 0.003
Echinococcus granulosus FTZ F1 alpha 0.0064 0.0208 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0008 0.0027
Trypanosoma brucei transcription factor BTF3, putative 0.0039 0.0111 0.0147
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0029 0.0112
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0209 0.0208
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0239
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0064 0.0208 0.0533
Echinococcus multilocularis muscleblind protein 1 0.0332 0.1283 0.1282
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0064 0.0208 0.0533
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.012 0.0467
Schistosoma mansoni multidrug resistance protein 0.0024 0.0049 0.008
Trichomonas vaginalis immunophilin, putative 0.0025 0.0056 0.0216
Brugia malayi Heterochromatin protein 1 0.0035 0.0093 0.0236
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0064 0.0208 0.0509
Brugia malayi sodium-independent organic anion transporter family protein 0.0125 0.0455 0.1167
Echinococcus granulosus multidrug resistance protein 1 0.0017 0.002 0.0032
Echinococcus multilocularis caspase 8 0.002 0.0034 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0049 0.0188
Echinococcus multilocularis dnaJ subfamily B 0.091 0.3593 0.3592
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0022 0.0042 0.0068
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0049 0.008
Schistosoma mansoni Smad4 0.0043 0.0126 0.0206
Plasmodium vivax GMP synthetase, putative 0.0037 0.0102 0.1287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0012 0.0045
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0096 0.0371
Echinococcus multilocularis ecdysone induced protein 78C 0.0064 0.0208 0.0208
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0049 0.0189
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0015 0.0014 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0715 0.2797
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1114 0.4359
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0285 0.1096 0.1797
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0074 0.0073
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0025 0.0056 0.0142
Brugia malayi mbt repeat family protein 0.0037 0.0102 0.0259
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.0092 0.0323 0.1747
Loa Loa (eye worm) mbt repeat family protein 0.0037 0.0102 0.0259
Loa Loa (eye worm) hypothetical protein 0.0027 0.0061 0.0154
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.065 0.2554 1
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.0049 0.0189
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0019 0.003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0137 0.0501 0.0822
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.065 0.2554 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.065 0.2554 1
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0025 0.0056 0.0142
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0064 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0064 0.0208 0.0533
Brugia malayi MAP kinase sur-1 0.0113 0.0408 0.1045
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.012 0.1018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0049 0.0188
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0027 0.0043
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0113 0.0408 0.0542
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0493 0.0655
Loa Loa (eye worm) hypothetical protein 0.0048 0.0145 0.0371
Echinococcus granulosus cpg binding protein 0.0068 0.0224 0.0367
Brugia malayi Hemopexin family protein 0.0111 0.0399 0.1024
Brugia malayi MH1 domain containing protein 0.0043 0.0126 0.032
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0035 0.0094 0.0124
Brugia malayi nuclear receptor RXR 0.0034 0.0089 0.0225
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0301 0.1159 0.2973
Brugia malayi MH2 domain containing protein 0.0043 0.0126 0.032
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0188
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0096 0.0371
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0064 0.0208 0.0208
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0061 0.008
Brugia malayi jmjC domain containing protein 0.0131 0.0477 0.1224
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0012 0.0045
Brugia malayi RNA, U transporter 1 0.0045 0.0134 0.0342
Toxoplasma gondii histone lysine methyltransferase SET1 0.0122 0.0443 0.3776
Plasmodium vivax JmjC domain containing protein 0.0035 0.0094 0.1186
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0022 0.0044 0.0057
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0096 0.0337 0.0831
Giardia lamblia Fructose-bisphosphate aldolase 0.065 0.2554 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0086 0.0296 0.0759
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0318 0.1224 0.6786
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.034 0.034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0049 0.0124
Loa Loa (eye worm) hypothetical protein 0.0048 0.0145 0.0371
Schistosoma mansoni thyroid hormone receptor 0.0126 0.0459 0.0754
Loa Loa (eye worm) hypothetical protein 0.0119 0.0432 0.1106
Trypanosoma cruzi metacaspase, putative 0.002 0.0034 0.0044
Plasmodium falciparum basic transcription factor 3b, putative 0.0039 0.0111 0.0614
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.0031 0.0049
Toxoplasma gondii hypothetical protein 0.0305 0.1172 1
Brugia malayi hypothetical protein 0.0018 0.0027 0.0068
Schistosoma mansoni lipoxygenase 0.0134 0.0491 0.0806
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0014 0.0011 0.0013
Plasmodium vivax importin-beta 2, putative 0.0016 0.0018 0.0213
Trichomonas vaginalis abcb9, putative 0.0024 0.0049 0.0189
Loa Loa (eye worm) jmjC domain-containing protein 0.0135 0.0492 0.1262
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0149 0.055 0.0549
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0493 0.0655
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0027 0.0103
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0019 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0049 0.0188
Toxoplasma gondii Alpha-galactosidase 0.0016 0.0019 0.0159
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0022 0.0044 0.0072
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.003 0.0074 0.0122
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0125 0.0455 0.0746
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0042 0.0122 0.0199
Trypanosoma cruzi MFS transporter, putative 0.0125 0.0455 0.0605
Echinococcus granulosus chromobox protein 1 0.0035 0.0093 0.0151
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0015 0.0014 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0032 0.0122
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.012 0.0613
Trichomonas vaginalis D-aminoacylase, putative 0.0048 0.0145 0.0566
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.0037 0.0102 0.0561
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0049 0.0048
Echinococcus multilocularis jumonji domain containing 1A 0.0035 0.0094 0.0093
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0024 0.0049 0.0411
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0021 0.0078
Onchocerca volvulus 0.0061 0.0199 0.0486
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0094 0.0153
Mycobacterium ulcerans hypothetical protein 0.0027 0.0061 0.0128
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0038 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0031 0.0116
Loa Loa (eye worm) hypothetical protein 0.0034 0.0089 0.0225
Schistosoma mansoni multidrug resistance protein 0.0024 0.0049 0.008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0067 0.0171
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.0461 0.1799 0.456
Brugia malayi beta-lactamase family protein 0.0048 0.0145 0.0371
Brugia malayi RNA recognition motif domain containing protein 0.0071 0.0239 0.0611
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0031 0.0077
Brugia malayi Cytochrome P450 family protein 0.0015 0.0014 0.0034
Loa Loa (eye worm) beta-lactamase 0.0048 0.0145 0.0371
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0025 0.0056 0.0216
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0011 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0094 0.0154
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0034 0.0281
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0022 0.0044 0.0167
Schistosoma mansoni nuclear hormone receptor 0.003 0.0074 0.0122
Onchocerca volvulus 0.0125 0.0455 0.1144
Echinococcus multilocularis cpg binding protein 0.0068 0.0224 0.0224
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0034 0.0281
Echinococcus multilocularis thyroid hormone receptor alpha 0.0126 0.0459 0.0459
Echinococcus multilocularis Polycystic kidney disease protein 0.0064 0.0209 0.0208
Loa Loa (eye worm) hypothetical protein 0.0125 0.0455 0.1167
Plasmodium falciparum multidrug resistance protein 1 0.0024 0.0049 0.0268
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0113 0.0408 0.3472
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0103 0.0235
Loa Loa (eye worm) glutaminase 2 0.0307 0.1182 0.3033
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0064 0.0208 0.0533
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0239
Brugia malayi Importin beta-1 subunit 0.0016 0.0018 0.0043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0493 0.0655
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0015 0.0014 0.0009
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0021 0.0038 0.007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0035 0.0133
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0015 0.0014 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0022 0.0042 0.0106
Loa Loa (eye worm) cysteine protease 0.0035 0.0096 0.0244
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0014 0.0011 0.0013
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0014 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0012 0.0045
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.012 0.0159
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0408 0.1593
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0064 0.0208 0.0341
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0188
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0019 0.0046
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.0049 0.0124
Echinococcus multilocularis mitogen activated protein kinase 0.0113 0.0408 0.0407
Entamoeba histolytica hypothetical protein 0.0072 0.0241 0.0942
Echinococcus multilocularis cysteine protease 0.0035 0.0096 0.0095
Trypanosoma brucei metacaspase MCA2 0.002 0.0034 0.0044
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0096 0.0126
Brugia malayi ecdysteroid receptor 0.0064 0.0208 0.0533
Echinococcus multilocularis cysteine protease 0.0035 0.0096 0.0095
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0029 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Mycobacterium tuberculosis Probable esterase LipL 0.0048 0.0145 0.0344
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0145 0.0193
Echinococcus multilocularis chromobox protein 1 0.0035 0.0093 0.0092
Echinococcus multilocularis agrin 0.0086 0.0296 0.0295
Treponema pallidum fructose-bisphosphate aldolase 0.065 0.2554 1
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.002 0.0034 0.0033
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0015 0.0014 0.0009
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0049 0.0189
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0208 0.0785 0.1975
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.003 0.0074 0.0188
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0064 0.0208 0.0208
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.002 0.0034 0.0055
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0894 0.3529 0.47
Mycobacterium tuberculosis Probable oxidoreductase 0.0017 0.0023 0.0033
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0115 0.0414 0.0679
Leishmania major cathepsin L-like protease 0.0035 0.0096 0.0126
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0017 0.0023 0.0193
Schistosoma mansoni sex comb on midleg homolog 0.0037 0.0102 0.0167
Brugia malayi Matrixin family protein 0.0079 0.0268 0.0687
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0715 0.2797
Echinococcus multilocularis adam 0.0018 0.0027 0.0027
Trypanosoma brucei hypothetical protein, conserved 0.0048 0.0145 0.0193
Loa Loa (eye worm) MH1 domain-containing protein 0.0043 0.0126 0.032
Loa Loa (eye worm) hypothetical protein 0.0096 0.0337 0.0862
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0064 0.0208 0.0533
Schistosoma mansoni jumonji/arid domain-containing protein 0.0135 0.0492 0.0808
Echinococcus granulosus agrin 0.0086 0.0296 0.0485
Onchocerca volvulus Netrin receptor homolog 0.0016 0.0019 0.0021
Entamoeba histolytica P-glycoprotein-2, putative 0.0024 0.0049 0.0189
Toxoplasma gondii target of rapamycin (TOR), putative 0.0017 0.0021 0.017
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0066 0.0218 0.0357
Echinococcus multilocularis fk506 binding protein 0.0025 0.0056 0.0055
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.0049 0.0048
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0049 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0021 0.0078
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.0037 0.0102 0.0134
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.065 0.2554 1
Echinococcus granulosus Polycystic kidney disease protein 0.0064 0.0209 0.0342
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0089 0.0225
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1114 0.4359
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.065 0.2554 1
Trichomonas vaginalis glucosylceramidase, putative 0.0201 0.0756 0.2958
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0141 0.0517 0.0516
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0125 0.0455 0.0454
Brugia malayi hypothetical protein 0.0986 0.3894 1
Echinococcus granulosus thyroid hormone receptor alpha 0.003 0.0074 0.012
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0042 0.0122 0.0121
Trypanosoma brucei metacaspase 5, putative 0.002 0.0034 0.0044
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0025 0.0056 0.0307
Brugia malayi nuclear hormone receptor 0.0064 0.0208 0.0533
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.034 0.0559
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0071 0.0239 0.0611
Brugia malayi hypothetical protein 0.0046 0.0139 0.0356
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.005 0.0153 0.0391
Schistosoma mansoni lozenge 0.0124 0.0449 0.0736
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0408 0.0669
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0019 0.0031
Schistosoma mansoni coup transcription factor 0.0064 0.0208 0.0342
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0015 0.0014 0.0009
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0016 0.0019 0.0032
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0015 0.0014 0.0009
Loa Loa (eye worm) hypothetical protein 0.0024 0.0049 0.0124
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0208 0.0785 1
Trypanosoma cruzi cruzipain precursor, putative 0.0135 0.0493 0.0655
Brugia malayi MH2 domain containing protein 0.0629 0.2468 0.6337
Loa Loa (eye worm) hypothetical protein 0.0064 0.0208 0.0533
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0096 0.0371
Loa Loa (eye worm) hypothetical protein 0.0048 0.0145 0.0371
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0239 0.0392
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0015 0.0014 0.0009
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0025 0.0056 0.0216
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0061 0.0154
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0014 0.0011 0.0013
Schistosoma mansoni ap endonuclease 0.0019 0.0029 0.0048
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0027 0.0068
Onchocerca volvulus 0.0035 0.0096 0.0219
Brugia malayi Cytochrome P450 family protein 0.0033 0.0088 0.0224
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0025 0.0056 0.0705
Toxoplasma gondii NAC domain-containing protein 0.0039 0.0111 0.0943
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.0027 0.0035
Echinococcus multilocularis importin subunit beta 1 0.0016 0.0018 0.0017
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0049 0.0048
Trypanosoma brucei protein kinase, putative 0.0113 0.0408 0.0542
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.003 0.0048
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0049 0.0079
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1889 0.7507 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0061 0.0281
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0235 0.0894 0.2295
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0014 0.0011 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0064 0.0208 0.0533
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0188
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0083 0.0285 0.0284
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0034 0.0089 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0493 0.0655
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0038 0.0205
Brugia malayi CXXC zinc finger family protein 0.0064 0.021 0.0537
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1889 0.7507 1
Echinococcus multilocularis Smad4 0.0043 0.0126 0.0125
Echinococcus granulosus caspase 8 0.002 0.0034 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0025 0.0096
Schistosoma mansoni smdr2 0.0024 0.0049 0.008
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0034 0.0281
Brugia malayi Cathepsin L-like precursor 0.0012 0.0001 0.0001
Echinococcus multilocularis ATP binding cassette sub family B 0.0023 0.0048 0.0047
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0008 0.0028
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0208 0.0785 0.4331
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0266 0.1016 0.1353
Loa Loa (eye worm) agrin synaptic family protein 0.0086 0.0296 0.0759
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0014 0.0011 0.0013
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0064 0.0208 0.0533
Echinococcus granulosus microtubule associated protein 2 0.1535 0.6093 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0046 0.0139 0.0356
Brugia malayi Matrixin family protein 0.0079 0.0268 0.0687
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0014 0.0011 0.0013
Echinococcus granulosus SAM and MBT domain containing protein 0.0037 0.0102 0.0165
Trichomonas vaginalis set domain proteins, putative 0.0267 0.1023 0.4005
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0064 0.0208 0.0533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0014 0.0052
Schistosoma mansoni steroid hormone receptor ad4bp 0.0064 0.0208 0.0342
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0014 0.0011 0.0054
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0049 0.0048
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0049 0.0189
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0064 0.0208 0.0208
Onchocerca volvulus 0.0079 0.0268 0.0663
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0096 0.0371
Brugia malayi nuclear receptor NHR-88 0.0064 0.0208 0.0533
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0015 0.0014 0.0009
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0249 0.095 0.1558
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0021 0.0078
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.0037 0.0102 0.0134
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0029 0.0112
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0025 0.0056 0.0216
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0014 0.0011 0.001
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0023 0.0048 0.0077
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0029 0.0074
Schistosoma mansoni rab6-interacting 0.0064 0.0209 0.0343
Echinococcus granulosus mothers against decapentaplegic 5 0.0043 0.0126 0.0205
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0015 0.0014 0.0009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0048 0.0121
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0022 0.0044 0.0057
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0074 0.0073
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0089 0.0225
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0005 0.0006
Schistosoma mansoni jumonji domain containing protein 0.0131 0.0477 0.0784
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0039 0.0108 0.0108
Onchocerca volvulus 0.0125 0.0455 0.1144
Loa Loa (eye worm) hypothetical protein 0.0048 0.0145 0.0371
Mycobacterium ulcerans esterase/lipase LipP 0.0048 0.0145 0.0344
Brugia malayi ecdysone receptor 0.003 0.0074 0.0188
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0188
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0034 0.0089 0.0225
Schistosoma mansoni cathepsin s 0.0012 0.0001 0.0002
Entamoeba histolytica cysteine protease, putative 0.0018 0.0027 0.0103
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0061 0.0154
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0015 0.0014 0.0009
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0094 0.0093
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0018 0.0027 0.0045
Trichomonas vaginalis chromobox protein, putative 0.0021 0.0038 0.0145
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0035 0.0133
Brugia malayi RNA binding protein 0.0071 0.0239 0.0611
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0021 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0111 0.0433
Loa Loa (eye worm) hypothetical protein 0.0079 0.0268 0.0687
Schistosoma mansoni Smad4 0.0019 0.0031 0.0051
Brugia malayi Calcitonin receptor-like protein seb-1 0.0301 0.1159 0.2973
Leishmania major metacaspase, putative 0.002 0.0034 0.0044
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.0461 0.1799 1
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.0092 0.0323 0.1262
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0029 0.0038
Brugia malayi Doublecortin family protein 0.0064 0.0209 0.0535
Schistosoma mansoni sex comb on midleg homolog 0.0037 0.0102 0.0167
Toxoplasma gondii cathepsin CPL 0.0035 0.0096 0.0809
Leishmania major cathepsin L-like protease 0.0135 0.0493 0.0655
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0077 0.0261 0.1019
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0034 0.0089 0.0088
Schistosoma mansoni smad1 5 8 and 0.0043 0.0126 0.0206
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0089 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0034 0.0129
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0025 0.0033
Schistosoma mansoni immunophilin 0.0025 0.0056 0.0092
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0034 0.0129
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0022 0.0042 0.0041
Mycobacterium tuberculosis Probable lipase LipE 0.0048 0.0145 0.0344
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0027 0.0068
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0049 0.0189
Schistosoma mansoni jumonji/arid domain-containing protein 0.0135 0.0492 0.0808
Loa Loa (eye worm) hypothetical protein 0.0064 0.0208 0.0533
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0493 0.0655
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0043
Entamoeba histolytica cysteine protease, putative 0.0018 0.0027 0.0103
Schistosoma mansoni smad 0.0043 0.0126 0.0206
Brugia malayi hypothetical protein 0.003 0.0074 0.0188
Trichomonas vaginalis penicillin-binding protein, putative 0.0048 0.0145 0.0566
Mycobacterium tuberculosis Conserved protein 0.0048 0.0145 0.0344
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0061 0.0235
Brugia malayi Cathepsin L-like precursor 0.0035 0.0096 0.0244
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0188
Onchocerca volvulus 0.0125 0.0455 0.1144
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.0049 0.0411
Schistosoma mansoni hypothetical protein 0.0095 0.0335 0.055
Schistosoma mansoni nuclear receptor 0.003 0.0074 0.0122
Loa Loa (eye worm) hypothetical protein 0.0034 0.0089 0.0225
Schistosoma mansoni hypothetical protein 0.0115 0.0413 0.0678
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0085
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0088 0.0116
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0064 0.0208 0.0342
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0025 0.0056 0.0092
Echinococcus granulosus muscleblind protein 0.0332 0.1283 0.2105
Schistosoma mansoni hypothetical protein 0.0072 0.0241 0.0396
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0113 0.0408 0.0542
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0012 0.0045
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0034 0.0129
Brugia malayi beta-lactamase 0.0048 0.0145 0.0371
Onchocerca volvulus 0.0037 0.0102 0.0234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Schistosoma mansoni hypothetical protein 0.0054 0.0171 0.028
Brugia malayi cathepsin L-like precursor 0.0024 0.0049 0.0124
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0034 0.0129
Loa Loa (eye worm) hypothetical protein 0.0037 0.0102 0.0259
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0015 0.0014 0.0009
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0005 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0061 0.0128
Brugia malayi prostaglandin transporter 0.0125 0.0455 0.1167
Echinococcus granulosus chromobox protein 1 0.0035 0.0093 0.0151
Trichomonas vaginalis glucosylceramidase, putative 0.029 0.1114 0.4359
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0015 0.0014 0.0009
Echinococcus multilocularis nuclear receptor nhr 48 0.003 0.0074 0.0073
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.0064 0.0208 0.0533
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0048 0.0145 0.0344
Echinococcus granulosus nuclear factor of activated T cells 5 0.0083 0.0285 0.0466
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0013 0.0006 0.0019
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0014 0.0011 0.0017
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0061 0.0128
Brugia malayi hypothetical protein 0.0028 0.0067 0.0171
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0037 0.0102 0.0167
Brugia malayi Latrophilin receptor protein 2 0.0095 0.0335 0.0859
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0061 0.0281
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0035 0.0133
Brugia malayi Melibiase family protein 0.0077 0.0261 0.0668
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0174 0.0651 0.1067
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0015 0.0014 0.0009
Loa Loa (eye worm) doublecortin family protein 0.0064 0.0209 0.0535
Brugia malayi jmjC domain containing protein 0.0035 0.0094 0.0239
Echinococcus multilocularis 0.0015 0.0014 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0493 0.0655
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0029 0.0112
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0015 0.0014 0.0009
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0015 0.0014 0.0009
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.005 0.0153 0.0251
Schistosoma mansoni immunophilin 0.0022 0.0042 0.0069
Plasmodium vivax vivapain-2 0.0035 0.0096 0.1209
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0025 0.0056 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0012 0.0045
Schistosoma mansoni jumonji domain containing protein 0.0035 0.0094 0.0154
Loa Loa (eye worm) hypothetical protein 0.0064 0.0209 0.0535
Schistosoma mansoni hypothetical protein 0.0064 0.0209 0.0343
Plasmodium falciparum enoyl-acyl carrier reductase 0.0208 0.0785 0.4362
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.003 0.0074 0.0073
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0025 0.0056 0.0216
Loa Loa (eye worm) transcription factor SMAD2 0.0629 0.2468 0.6337
Schistosoma mansoni hypothetical protein 0.0169 0.0629 0.1032
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0027 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0012 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0096 0.0371
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0074 0.0164
Trypanosoma cruzi cysteine protease, putative 0.0018 0.0027 0.0035
Entamoeba histolytica cysteine proteinase 1, putative 0.0018 0.0027 0.0103
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0061 0.0128
Echinococcus granulosus adam 0.0018 0.0027 0.0044
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0113 0.0408 0.0542
Onchocerca volvulus Matrilysin homolog 0.0174 0.065 0.1648
Mycobacterium tuberculosis Conserved protein 0.0048 0.0145 0.0344
Brugia malayi cathepsin F-like cysteine proteinase 0.0012 0.0001 0.0001
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0049 0.0189
Echinococcus granulosus RUN 0.0064 0.0209 0.0342
Onchocerca volvulus 0.0064 0.0209 0.0512
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.008
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0049 0.0189
Treponema pallidum NAD synthetase 0.0092 0.0323 0.1163
Echinococcus multilocularis pol protein 0.2513 1 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.0208 0.0533
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0049 0.0079
Mycobacterium tuberculosis Conserved hypothetical protein 0.0995 0.3933 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0094 0.0239
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0064 0.0208 0.0341
Brugia malayi hypothetical protein 0.003 0.0074 0.0188
Schistosoma mansoni importin beta-1 0.0016 0.0018 0.0029
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0014 0.0022
Schistosoma mansoni organic anion transporter 0.0125 0.0455 0.0747
Onchocerca volvulus 0.0125 0.0455 0.1144
Schistosoma mansoni cpg binding protein 0.0068 0.0224 0.0368
Loa Loa (eye worm) solute carrier family 6 member 4 0.0061 0.0199 0.051
Onchocerca volvulus Glucosylceramidase homolog 0.019 0.0715 0.1814
Onchocerca volvulus Putative organic anion transporter 0.0125 0.0455 0.1144
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0049 0.0189
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.0461 0.1799 1
Echinococcus granulosus dnaJ subfamily B 0.091 0.3593 0.5896
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0029 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0064 0.0208 0.0533
Schistosoma mansoni microtubule-associated protein tau 0.1535 0.6093 1
Entamoeba histolytica cysteine protease, putative 0.0018 0.0027 0.0103
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0022 0.0044 0.007
Schistosoma mansoni cpg binding protein 0.0064 0.021 0.0344
Echinococcus multilocularis cathepsin L 0.0018 0.0027 0.0026
Onchocerca volvulus 0.0035 0.0096 0.0219
Schistosoma mansoni hypothetical protein 0.0095 0.0335 0.055
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.0031 0.003
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0175 0.0448
Echinococcus granulosus TGF beta signal transducer SmadC 0.0043 0.0126 0.0205
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0049 0.0189
Brugia malayi Cathepsin L-like precursor 0.0024 0.0049 0.0124
Loa Loa (eye worm) fibroinase 0.0035 0.0096 0.0244
Toxoplasma gondii melibiase subfamily protein 0.0115 0.0414 0.3528
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.0092 0.0323 0.275
Loa Loa (eye worm) hypothetical protein 0.0024 0.0049 0.0124
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0171 0.0437
Schistosoma mansoni netrin receptor unc5 0.0016 0.0019 0.0031
Loa Loa (eye worm) MH2 domain-containing protein 0.0629 0.2468 0.6337
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0064 0.0208 0.0533
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0086 0.0296 0.2521
Onchocerca volvulus 0.0054 0.0171 0.0413
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0034 0.0129
Echinococcus granulosus apoptotic protease activating factor 1 0.0046 0.0139 0.0227
Echinococcus granulosus polycomb protein SCMH1 0.0037 0.0102 0.0165
Echinococcus granulosus cathepsin L 0.0018 0.0027 0.0043
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0048 0.0145 0.0344
Echinococcus multilocularis chromobox protein 1 0.0035 0.0093 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0715 0.2797
Loa Loa (eye worm) hypothetical protein 0.0064 0.0208 0.0533
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0049 0.0189
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0015 0.0014 0.0009
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.0044 0.011
Echinococcus granulosus a disintegrin and metalloproteinase with 0.005 0.0153 0.025
Plasmodium vivax vivapain-2 0.0035 0.0096 0.1209
Echinococcus multilocularis caspase 0.002 0.0034 0.0033
Schistosoma mansoni protein phosphatase 2C 0.0035 0.0094 0.0154
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0239 0.0392
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0096 0.0371
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Leishmania major cytochrome p450-like protein 0.0015 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.0037 0.0102 0.0259
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0019 0.0032
Loa Loa (eye worm) ICD-1 protein 0.0039 0.0111 0.0284
Echinococcus multilocularis JmjC domain containing protein 4 0.0035 0.0094 0.0093
Schistosoma mansoni loxhd1 0.0064 0.0209 0.0343
Brugia malayi Matrixin family protein 0.0079 0.0268 0.0687
Entamoeba histolytica hypothetical protein 0.0072 0.0241 0.0942
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.065 0.2554 1
Trichomonas vaginalis D-aminoacylase, putative 0.0048 0.0145 0.0566
Echinococcus granulosus caspase 2 0.0066 0.0219 0.0358
Onchocerca volvulus 0.0268 0.1024 0.2609
Loa Loa (eye worm) hypothetical protein 0.0048 0.0145 0.0371
Echinococcus multilocularis smad 0.0043 0.0126 0.0125
Schistosoma mansoni caspase-7 (C14 family) 0.002 0.0034 0.0055
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0025 0.0056 0.0055
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0239 0.0392
Loa Loa (eye worm) MBCTL1 0.0042 0.0122 0.0311
Brugia malayi MH2 domain containing protein 0.0043 0.0126 0.032
Schistosoma mansoni hypothetical protein 0.0015 0.0014 0.0023
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0096 0.0156
Brugia malayi Cell death protein 3 precursor 0.0066 0.0219 0.056
Entamoeba histolytica hypothetical protein 0.0039 0.0111 0.0433
Brugia malayi nuclear hormone receptor 0.003 0.0074 0.0188
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0188
Trichomonas vaginalis taga, putative 0.0024 0.0049 0.0189
Loa Loa (eye worm) hypothetical protein 0.0125 0.0455 0.1167
Echinococcus granulosus follistatin 0.0086 0.0296 0.0485
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0266 0.1016 0.1353
Echinococcus granulosus geminin 0.0252 0.0963 0.158
Onchocerca volvulus Protein ultraspiracle homolog 0.0064 0.0208 0.0509
Brugia malayi nuclear receptor NHR-88 0.003 0.0074 0.0188
Brugia malayi Nuclear hormone receptor-like 1 0.0064 0.0208 0.0533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0003 0.0007
Echinococcus multilocularis mothers against decapentaplegic 5 0.0043 0.0126 0.0125
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0029 0.0029
Schistosoma mansoni smad1 5 8 and 0.0043 0.0126 0.0206
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0027 0.0045
Plasmodium vivax vivapain-3 0.0018 0.0027 0.0335
Brugia malayi multidrug resistance protein 3 0.0024 0.0049 0.0124
Onchocerca volvulus 0.0064 0.021 0.0513
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0188
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0064 0.0208 0.0533
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0067 0.0371
Trypanosoma brucei metacaspase MCA3 0.002 0.0034 0.0044
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0049 0.0079
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0015 0.0014 0.0009
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0023 0.0022
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.012 0.0159
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0093 0.036
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.0461 0.1799 1
Echinococcus multilocularis pol protein 0.2513 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0021 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Echinococcus granulosus death domain containing protein 0.0016 0.0019 0.003
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0034 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0012 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0033
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0096 0.0337 0.0862
Onchocerca volvulus 0.0027 0.0061 0.0129
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0027 0.0035
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0096 0.0219
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0061 0.0128
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0249 0.095 0.0949
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0095 0.0335 0.0859
Onchocerca volvulus 0.0024 0.0049 0.0099
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0048 0.0145 0.0371
Loa Loa (eye worm) matrixin family protein 0.0174 0.065 0.1669
Echinococcus multilocularis multidrug resistance protein 1 0.0017 0.002 0.002
Loa Loa (eye worm) matrix metalloproteinase 0.0079 0.0268 0.0687
Brugia malayi mbt repeat family protein 0.0037 0.0102 0.0259
Entamoeba histolytica cysteine protease, putative 0.0018 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0096 0.0371
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0088 0.0224
Schistosoma mansoni hypothetical protein 0.0228 0.0864 0.1419
Echinococcus granulosus importin subunit beta 1 0.0016 0.0018 0.0027
Mycobacterium ulcerans GMP synthase 0.0037 0.0102 0.0232
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0024 0.0049 0.0098
Echinococcus granulosus cathepsin l1 0.0024 0.0049 0.0079
Onchocerca volvulus 0.0035 0.0096 0.0219
Onchocerca volvulus 0.0064 0.0209 0.0512
Plasmodium falciparum importin beta, putative 0.0016 0.0018 0.0093
Echinococcus granulosus ecdysone induced protein 78C 0.0064 0.0208 0.0341
Onchocerca volvulus 0.0015 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0048 0.0145 0.0371
Loa Loa (eye worm) hypothetical protein 0.0125 0.0455 0.1167
Loa Loa (eye worm) hypothetical protein 0.0332 0.1283 0.3293
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0037 0.0102 0.0234
Trypanosoma brucei pteridine reductase 1 0.0014 0.0011 0.0013
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0015 0.0014 0.0009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0035 0.0133
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.0049 0.0189
Loa Loa (eye worm) hypothetical protein 0.0125 0.0455 0.1167
Loa Loa (eye worm) hypothetical protein 0.0024 0.0049 0.0124
Schistosoma mansoni hypothetical protein 0.0063 0.0205 0.0337
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0049 0.0079
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0096 0.0157
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0149 0.055 0.0901
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0067 0.085
Plasmodium falciparum metacaspase-like protein 0.002 0.0034 0.0183
Trypanosoma brucei importin beta-1 subunit, putative 0.0016 0.0018 0.0022
Onchocerca volvulus Huntingtin homolog 0.0102 0.0363 0.0909
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0015 0.0014 0.0009
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0894 0.3529 0.47
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0086 0.0296 0.0759
Mycobacterium ulcerans glutaminase 0.0307 0.1182 0.2986
Schistosoma mansoni agrin 0.0086 0.0296 0.0486
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0077 0.0261 0.0428
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0064 0.0208 0.0341
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0022 0.0044 0.0057
Echinococcus granulosus jumonji domain containing 1A 0.0035 0.0094 0.0153
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0015 0.0014 0.0009
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0035 0.0094 0.0794
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0034 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0025 0.0096
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0064 0.0208 0.0208
Loa Loa (eye worm) heterochromatin protein 1 0.0035 0.0093 0.0236
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0015 0.0014 0.0009
Brugia malayi nuclear hormone receptor family member nhr-6 0.003 0.0074 0.0188
Loa Loa (eye worm) hypothetical protein 0.0332 0.1283 0.3293
Loa Loa (eye worm) hypothetical protein 0.0986 0.3894 1
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0125 0.0455 0.1167
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0011 0.0025
Leishmania major cathepsin L-like protease 0.0035 0.0096 0.0126
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0086 0.0296 0.0759
Echinococcus multilocularis survival motor neuron protein 1 0.0266 0.1016 0.1015
Trichomonas vaginalis helicase, putative 0.0014 0.0012 0.0045
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0188
Mycobacterium leprae Probable lipase LipE 0.0048 0.0145 0.0754
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0034 0.013
Brugia malayi jmjC domain containing protein 0.0135 0.0492 0.1262
Loa Loa (eye worm) TAR-binding protein 0.0071 0.0239 0.0611
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0408 0.1593
Trichomonas vaginalis abcb9, putative 0.0024 0.0049 0.0189
Echinococcus multilocularis caspase 2 0.0066 0.0219 0.0218
Schistosoma mansoni hypothetical protein 0.091 0.3593 0.5897
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0035 0.0133
Loa Loa (eye worm) FKBP5 protein 0.0025 0.0056 0.0142
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0049 0.0124
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.034 0.034
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0027 0.0061 0.0154
Loa Loa (eye worm) Smad1 0.0043 0.0126 0.032
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0115 0.0414 0.068
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.0031 0.003
Brugia malayi ABC transporter family protein 0.0024 0.0049 0.0124
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0408 0.1593
Brugia malayi MH1 domain containing protein 0.0024 0.0049 0.0124
Loa Loa (eye worm) hypothetical protein 0.0024 0.0049 0.0124
Brugia malayi Steroid receptor seven-up type 2 0.0064 0.0208 0.0533
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0035 0.0133
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0024 0.0049 0.0215
Brugia malayi Matrixin family protein 0.0079 0.0268 0.0687
Schistosoma mansoni lipoxygenase 0.0249 0.095 0.1559
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0095 0.0335 0.0549
Leishmania major pteridine reductase 1 0.0017 0.0023 0.003
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0019 0.0046
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0096 0.0219
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0049 0.0189
Plasmodium vivax unspecified product 0.0018 0.0027 0.0335
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0015 0.0014 0.0009
Loa Loa (eye worm) ctsf protein 0.0035 0.0096 0.0244
Echinococcus multilocularis mitogen activated protein kinase 3 0.0113 0.0408 0.0407
Echinococcus multilocularis phd:f box containing protein 0.0035 0.0094 0.0093
Echinococcus multilocularis geminin 0.0252 0.0963 0.0963
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0025 0.0096
Brugia malayi Cathepsin L-like precursor 0.0035 0.0096 0.0244
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0085
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0049 0.0048
Loa Loa (eye worm) hypothetical protein 0.0266 0.1016 0.2607
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0188
Entamoeba histolytica P-glycoprotein-2 0.0024 0.0049 0.0189
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0049 0.0189
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0113 0.0408 0.0542
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0049 0.0189
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0027 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0034 0.0129
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0005 0.0016
Mycobacterium ulcerans hydrolase 0.0096 0.0337 0.0831
Brugia malayi nuclear receptor NHR-67 0.003 0.0074 0.0188
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0025 0.0056 0.0116
Toxoplasma gondii transporter, major facilitator family protein 0.0125 0.0455 0.3877
Leishmania major cathepsin L-like protease 0.0135 0.0493 0.0655
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.012 0.0467
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.065 0.2554 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0239
Trichomonas vaginalis chromobox protein, putative 0.0021 0.0038 0.0145
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0019 0.0018
Schistosoma mansoni polycystin 1-related 0.0064 0.0209 0.0343
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0064 0.0208 0.0533
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0025 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0025 0.0096
Loa Loa (eye worm) nuclear receptor NHR-67 0.003 0.0074 0.0188
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0034 0.0129
Schistosoma mansoni phd/f-box containing protein 0.0035 0.0094 0.0154
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0077 0.0261 0.0428
Brugia malayi Protein kinase domain containing protein 0.0017 0.0023 0.0057
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0043 0.0126 0.0125
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0097 0.034 0.0559
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0046
Trypanosoma brucei RNA helicase, putative 0.0115 0.0413 0.0549
Onchocerca volvulus 0.003 0.0074 0.0164
Loa Loa (eye worm) hypothetical protein 0.0301 0.1159 0.2973
Brugia malayi hypothetical protein 0.0266 0.1016 0.2607
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0014 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0021 0.0078
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0015 0.0014 0.0009
Loa Loa (eye worm) hypothetical protein 0.0035 0.0096 0.0244
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0241 0.0395
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0063 0.0205 0.0336
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0017 0.0023 0.003
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0025 0.0056 0.0105
Echinococcus granulosus bloom syndrome protein 0.0024 0.0049 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0064 0.0208 0.0533
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0064 0.0208 0.0341
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0123 0.0446 0.0593
Toxoplasma gondii HEAT repeat-containing protein 0.0016 0.0018 0.0142
Loa Loa (eye worm) steroid hormone receptor 0.0064 0.0208 0.0533
Echinococcus multilocularis snurportin 1 0.0169 0.0629 0.0628
Onchocerca volvulus 0.0986 0.3894 1
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0408 0.1593
Loa Loa (eye worm) hypothetical protein 0.0066 0.0219 0.056
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0061 0.0199 0.051
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0113 0.0408 0.0542
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0005 0.0006
Plasmodium vivax multidrug resistance protein 1, putative 0.0024 0.0049 0.0614
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0014 0.0018
Schistosoma mansoni chromobox protein 0.0035 0.0093 0.0152
Brugia malayi nuclear receptor RXR 0.003 0.0074 0.0188
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0048 0.0145 0.0239
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.012 0.0196
Echinococcus multilocularis pol protein 0.2513 1 1
Schistosoma mansoni GMP synthetase 0.0037 0.0102 0.0167
Echinococcus granulosus mitogen activated protein kinase 0.0113 0.0408 0.0668
Onchocerca volvulus Bile acid receptor homolog 0.0064 0.0208 0.0509
Echinococcus multilocularis serotonin transporter 0.0061 0.0199 0.0198
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0027 0.0061 0.0154
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0096 0.0219
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0034 0.0129
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0027 0.0045
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0035 0.0094 0.0154
Leishmania major hypothetical protein, conserved 0.0028 0.0067 0.0089
Trypanosoma brucei oxidoreductase-like protein 0.0017 0.0023 0.003
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0034 0.0129
Echinococcus multilocularis FTZ F1 alpha 0.0064 0.0208 0.0208
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0024 0.0049 0.0064
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0017 0.002 0.0077
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0092 0.0323 0.053
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0015 0.0014 0.0009
Loa Loa (eye worm) runx1 0.0124 0.0449 0.115
Brugia malayi TAR-binding protein 0.0071 0.0239 0.0611
Loa Loa (eye worm) hypothetical protein 0.0086 0.0296 0.0759
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.012 0.0159
Entamoeba histolytica P-glycoprotein 5, putative 0.0024 0.0049 0.0189
Loa Loa (eye worm) hypothetical protein 0.0102 0.0363 0.0931
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0008 0.0027
Onchocerca volvulus 0.003 0.0074 0.0164
Entamoeba histolytica P-glyco protein 6, putative 0.0024 0.0049 0.0189
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0266 0.1016 0.1353
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0083 0.0136
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0049 0.0189
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0014 0.0011 0.0013
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.0049 0.0048
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0077
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0029 0.0106
Brugia malayi Cathepsin L-like precursor 0.0035 0.0096 0.0244
Echinococcus multilocularis expressed protein 0.0086 0.0296 0.0295
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0029 0.0047

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 80 mg kg-1 Anticonvulsant activity in mouse maximal electroshock assay following i.p. administration. ChEMBL. 7205879
ND50 (functional) > 300 mg kg-1 Dose causing a neurological deficit in 50% of mice after ip administration. ChEMBL. 7205879
PI (functional) > 3.8 Protective index of the compound is defined as ND50 (i.p.) divided by MES ED50(i.p.) ChEMBL. 7205879

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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