Detailed information for compound 373760

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 395.534 | Formula: C25H33NO3
  • H donors: 2 H acceptors: 3 LogP: 5.06 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H]1C[C@@H]2CCCC[C@H]2[C@@H]([C@@H]1[C@H](O)C)/C=C/c1ccc2c(n1)ccc(c2)OC
  • InChi: 1S/C25H33NO3/c1-16(28)25-19(15-27)13-17-5-3-4-6-22(17)23(25)11-9-20-8-7-18-14-21(29-2)10-12-24(18)26-20/h7-12,14,16-17,19,22-23,25,27-28H,3-6,13,15H2,1-2H3/b11-9+/t16-,17+,19+,22-,23+,25-/m1/s1
  • InChiKey: SYAKWKHSZASVSS-ZIWANMDKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor II (thrombin) receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Schistosoma mansoni acetyl-CoA synthetase 0.011 0.0119 0.0176
Echinococcus granulosus heat shock protein 90 0.0097 0.0101 0.0151
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.002 0.0048
Loa Loa (eye worm) hypothetical protein 0.0069 0.0062 0.0157
Echinococcus multilocularis serotonin receptor 0.0026 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0128 0.0143 0.0363
Plasmodium falciparum mitogen-activated protein kinase 2 0.0153 0.0177 0.0482
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0061 0.0051 0.0075
Trypanosoma brucei heat shock protein, putative 0.0115 0.0126 0.0317
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0025 0.0003 0.0002
Schistosoma mansoni nuclear receptor 0.0047 0.0033 0.0047
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0355 0.119
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.0309 0.039 0.0996
Loa Loa (eye worm) neuropeptide F receptor 0.0026 0.0003 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0226 0.0277 0.0928
Plasmodium vivax glutathione reductase, putative 0.0129 0.0145 0.0389
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.004 0.0101
Loa Loa (eye worm) patched family protein 0.0026 0.0005 0.001
Schistosoma mansoni chloride channel protein 0.0172 0.0203 0.0301
Toxoplasma gondii protein kinase, putative 0.0267 0.0333 0.0846
Brugia malayi CHD4 protein 0.0037 0.0019 0.0046
Echinococcus multilocularis G protein coupled receptor 139 0.0026 0.0003 0.0003
Brugia malayi Augmenter of liver regeneration 0.0028 0.0007 0.0017
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0128 0.0143 0.0213
Schistosoma mansoni protein kinase 0.0029 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0048
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0012 0.0025
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0013 0.0028
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0048 0.0034 0.0085
Mycobacterium tuberculosis Probable dehydrogenase 0.0294 0.037 0.0941
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0045 0.003 0.008
Echinococcus multilocularis integrin beta 2 0.0115 0.0125 0.0125
Trypanosoma brucei mitochondrial DNA polymerase beta 0.023 0.0283 0.0717
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0012 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0281 0.0351 0.0897
Echinococcus granulosus biogenic amine 5HT receptor 0.0026 0.0003 0.0005
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0028 0.0007 0.0011
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0029 0.0009 0.0009
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0042 0.0026 0.0038
Brugia malayi Integrin beta pat-3 precursor 0.0155 0.018 0.0459
Schistosoma mansoni nAChR subunit 0.0128 0.0143 0.0211
Trypanosoma brucei glucose transporter, putative 0.0029 0.0009 0.0016
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0019 0.0043
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0029 0.0008 0.0008
Loa Loa (eye worm) DR-78 0.0047 0.0033 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0355 0.119
Plasmodium falciparum calcium-dependent protein kinase 5 0.0029 0.0009 0.0023
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0025 0.0003 0.0002
Brugia malayi AKH receptor 0.0026 0.0003 0.0007
Onchocerca volvulus 0.0077 0.0074 0.0247
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Mycobacterium ulcerans acyl-CoA synthetase 0.011 0.0119 0.0298
Trichomonas vaginalis set domain proteins, putative 0.2206 0.2976 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0586 0.0768 0.1963
Brugia malayi MH2 domain containing protein 0.0061 0.0051 0.0129
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0133 0.015 0.0381
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0069 0.0063 0.0156
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0069 0.0063 0.0156
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0187 0.0224 0.0572
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0326 0.0413 0.1387
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0007 0.0011
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0026 0.0003 0.0003
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0045 0.003 0.0044
Echinococcus multilocularis hyperpolarization activated cyclic 0.0029 0.0008 0.0008
Trypanosoma cruzi GMP reductase 0.2889 0.3909 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0099 0.0104 0.0155
Mycobacterium tuberculosis Probable reductase 0.0294 0.037 0.0941
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0133 0.015 0.0223
Onchocerca volvulus 0.0128 0.0143 0.0479
Echinococcus multilocularis neuropeptide receptor A26 0.0973 0.1295 0.1295
Toxoplasma gondii thioredoxin reductase 0.0129 0.0145 0.0364
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Brugia malayi chromobox protein homolog 3 0.0079 0.0076 0.0193
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.003 0.007
Trypanosoma cruzi hypothetical protein, conserved 0.0201 0.0243 0.0616
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0025 0.0003 0.0002
Trypanosoma cruzi heat shock protein 90, putative 0.0115 0.0126 0.0317
Mycobacterium leprae Probable lipase LipE 0.0201 0.0243 0.0615
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0026 0.0003 0.0004
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0374 0.0479 0.0715
Brugia malayi nuclear receptor NHR-88 0.0099 0.0104 0.0264
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0172 0.0203 0.0203
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0265 0.033 0.0839
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0019 0.0043
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0041 0.0025 0.0061
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0267 0.0332 0.0332
Mycobacterium tuberculosis Conserved protein 0.0172 0.0203 0.0512
Brugia malayi cytoplasmic intermediate filament protein 0.0041 0.0025 0.0061
Trichomonas vaginalis alpha-glucosidase, putative 0.0025 0.0002 0.0006
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0026 0.0003 0.0007
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.0172 0.0203 0.0512
Echinococcus multilocularis neuropeptides capa receptor 0.0026 0.0003 0.0003
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0028 0.0007 0.0013
Mycobacterium tuberculosis Carboxylesterase LipT 0.0309 0.039 0.0992
Echinococcus multilocularis dna polymerase kappa 0.0033 0.0013 0.0013
Echinococcus multilocularis zinc finger protein 0.0088 0.0089 0.0089
Echinococcus granulosus Threonyl tRNA synthetase C 0.0025 0.0003 0.0004
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.1517 0.2037 0.5209
Treponema pallidum fructose-bisphosphate aldolase 0.0283 0.0355 0.594
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0084 0.0282
Brugia malayi Hsp90 protein 0.0071 0.0065 0.0165
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0025 0.0003 0.0002
Schistosoma mansoni chromobox protein 0.0141 0.016 0.0238
Brugia malayi Bromodomain containing protein 0.0032 0.0012 0.0029
Trichomonas vaginalis heat shock protein, putative 0.0063 0.0055 0.0183
Trypanosoma brucei heat shock protein 90, putative 0.0115 0.0126 0.0317
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0025 0.0003 0.0002
Mycobacterium ulcerans lipase LipD 0.0201 0.0243 0.0615
Trypanosoma cruzi heat shock protein 85, putative 0.0115 0.0126 0.0317
Trypanosoma brucei glucose transporter, putative 0.0029 0.0009 0.0016
Brugia malayi PHD-finger family protein 0.011 0.0119 0.0303
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0338 0.0429 0.0641
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0033 0.0013 0.0042
Echinococcus multilocularis nAChR subunit 0.0128 0.0143 0.0143
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0057 0.0139
Onchocerca volvulus 0.0026 0.0005 0.0016
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0047 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0076 0.0072 0.0181
Echinococcus granulosus voltage gated potassium channel 0.0041 0.0024 0.0036
Plasmodium vivax endoplasmin, putative 0.0115 0.0126 0.0338
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0048 0.0034 0.0049
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.011 0.0119 0.0302
Echinococcus granulosus carboxylesterase 5A 0.1829 0.2463 0.3676
Echinococcus multilocularis GPCR, family 2 0.025 0.0309 0.0309
Brugia malayi putative neuropeptide receptor NPR1 0.0026 0.0003 0.0007
Entamoeba histolytica hypothetical protein 0.0069 0.0062 0.1102
Schistosoma mansoni neurotransmitter gated ion channel 0.0069 0.0062 0.0092
Loa Loa (eye worm) TYRA-2 protein 0.0026 0.0003 0.0007
Schistosoma mansoni neuropeptide receptor 0.0026 0.0003 0.0004
Brugia malayi Myosin head containing protein 0.0026 0.0005 0.001
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0099 0.0104 0.0154
Echinococcus granulosus prolyl tRNA synthetase mitochondrial 0.0066 0.0058 0.0087
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0012 0.0024
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0133 0.015 0.015
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0294 0.037 0.0941
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0081
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0032 0.0013 0.0027
Brugia malayi Carboxylesterase family protein 0.0309 0.039 0.0996
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0128 0.0143 0.0143
Loa Loa (eye worm) heat shock protein 75 0.0071 0.0065 0.0165
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0029 0.0009 0.0013
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0025 0.0003 0.0005
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.046 0.0595 0.0595
Echinococcus multilocularis lamin dm0 0.0077 0.0074 0.0074
Brugia malayi hypothetical protein 0.0053 0.004 0.0101
Chlamydia trachomatis GutQ/KpsF family sugar-phosphate isomerase 0.0172 0.0203 0.3375
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Echinococcus multilocularis importin subunit beta 1 0.004 0.0023 0.0023
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0094 0.0097 0.0145
Loa Loa (eye worm) hypothetical protein 0.011 0.0119 0.0302
Echinococcus multilocularis somatostatin receptor 0.0026 0.0003 0.0003
Giardia lamblia Glycyl-tRNA synthetase 0.0025 0.0003 0.0068
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0033 0.0033
Echinococcus granulosus histone lysine methyltransferase setb 0.035 0.0446 0.0666
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0029 0.0009 0.0016
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0008 0.0011
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0525 0.0684 0.1746
Leishmania major trypanothione reductase 0.0129 0.0145 0.0364
Schistosoma mansoni neuropeptide f receptor 76f 0.0026 0.0003 0.0004
Trichomonas vaginalis glutathione reductase, putative 0.0045 0.003 0.0098
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0037 0.002 0.0044
Onchocerca volvulus 0.0026 0.0005 0.0016
Schistosoma mansoni methyl-cpg binding protein mbd 0.007 0.0064 0.0095
Echinococcus multilocularis mothers against decapentaplegic 2 0.0027 0.0006 0.0006
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.025 0.0309 0.0309
Mycobacterium leprae Conserved hypothetical protein 0.0025 0.0003 0.0002
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0108 0.0116 0.0291
Trypanosoma cruzi ISWI complex protein 0.0063 0.0054 0.0134
Chlamydia trachomatis Mg++ transporter 0.0172 0.0203 0.3375
Schistosoma mansoni bromodomain containing protein 0.0026 0.0003 0.0004
Echinococcus granulosus microtubule associated protein 2 0.4937 0.6702 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0083 0.0082 0.0123
Schistosoma mansoni neuropeptide receptor 0.0026 0.0003 0.0004
Echinococcus granulosus muscleblind protein 0.0197 0.0237 0.0353
Brugia malayi hypothetical protein 0.0053 0.004 0.0101
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0029 0.0009 0.0016
Brugia malayi photoreceptor-specific nuclear receptor 0.0099 0.0104 0.0264
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0057 0.0138
Schistosoma mansoni tar DNA-binding protein 0.0395 0.0507 0.0756
Giardia lamblia Threonyl-tRNA synthetase 0.0025 0.0003 0.0068
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Toxoplasma gondii CBS domain-containing protein 0.0172 0.0203 0.0513
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0033 0.0013 0.0018
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0045 0.003 0.0074
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.025 0.0309 0.0309
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0105 0.0112 0.028
Schistosoma mansoni neurotransmitter gated ion channel 0.0059 0.0049 0.0072
Schistosoma mansoni biogenic amine receptor 0.0026 0.0003 0.0004
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0033 0.0013 0.0028
Echinococcus multilocularis neuroligin 0.0309 0.039 0.039
Trypanosoma brucei importin beta-1 subunit, putative 0.004 0.0023 0.0054
Leishmania major hypothetical protein, conserved 0.0037 0.002 0.0044
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0028 0.0007 0.0179
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0069 0.0062 0.0092
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.0003 0.0005
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0026 0.0003 0.0007
Onchocerca volvulus 0.0026 0.0005 0.0016
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.2889 0.3909 1
Brugia malayi exodeoxyribonuclease III family protein 0.0108 0.0116 0.0294
Brugia malayi hypothetical protein 0.0059 0.0049 0.0123
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Onchocerca volvulus 0.0026 0.0003 0.0012
Brugia malayi MH1 domain containing protein 0.0061 0.0051 0.0129
Echinococcus granulosus Protein patched homolog 1 0.0187 0.0224 0.0335
Giardia lamblia Fructose-bisphosphate aldolase 0.0283 0.0355 1
Schistosoma mansoni ap endonuclease 0.0108 0.0116 0.0171
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0099 0.0104 0.0104
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0025 0.0002 0.0006
Echinococcus multilocularis isocitrate dehydrogenase 0.0069 0.0063 0.0063
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.046 0.0595 0.1517
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0028 0.0007 0.0113
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0121 0.0134 0.0447
Onchocerca volvulus 0.0103 0.0109 0.0367
Leishmania major DNA polymerase eta, putative 0.0033 0.0013 0.0028
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0172 0.0203 0.0512
Trichomonas vaginalis D-aminoacylase, putative 0.0201 0.0243 0.0815
Loa Loa (eye worm) carboxylesterase 0.0309 0.039 0.0996
Loa Loa (eye worm) hypothetical protein 0.0027 0.0006 0.0012
Toxoplasma gondii hypothetical protein 0.0037 0.0019 0.0044
Echinococcus multilocularis allatostatin A receptor 0.0026 0.0003 0.0003
Brugia malayi Cytochrome P450 family protein 0.0025 0.0003 0.0007
Schistosoma mansoni nAChR subunit 0.0128 0.0143 0.0211
Mycobacterium tuberculosis Probable lipase LipE 0.0201 0.0243 0.0615
Brugia malayi hypothetical protein 0.0026 0.0003 0.0007
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0259 0.0321 0.082
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0026 0.0003 0.0003
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.025 0.0309 0.0789
Trypanosoma brucei heat shock protein, putative 0.0115 0.0126 0.0317
Echinococcus multilocularis neuropeptide Y receptor 0.0026 0.0003 0.0003
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.011 0.0119 0.0177
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0025 0.0003 0.0005
Brugia malayi beta-lactamase 0.0201 0.0243 0.0619
Plasmodium vivax CDK-related protein kinase 6, putative 0.0401 0.0515 0.1398
Brugia malayi hypothetical protein 0.0026 0.0003 0.0007
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0053 0.004 0.0098
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.046 0.0595 1
Loa Loa (eye worm) hypothetical protein 0.0281 0.0351 0.0897
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.011 0.0119 0.0298
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0375 0.0481 0.1224
Loa Loa (eye worm) hypothetical protein 0.0375 0.0481 0.1228
Schistosoma mansoni hypothetical protein 0.025 0.0309 0.046
Schistosoma mansoni nAChR subunit 0.0128 0.0143 0.0211
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Schistosoma mansoni neurotransmitter gated ion channel 0.0059 0.0049 0.0072
Loa Loa (eye worm) thioredoxin reductase 0.0129 0.0145 0.0368
Echinococcus granulosus fetal alzheimer antigen falz 0.0099 0.0103 0.0154
Schistosoma mansoni endoplasmin 0.0115 0.0126 0.0187
Onchocerca volvulus 0.0026 0.0003 0.0012
Leishmania major hypothetical protein, conserved 0.0201 0.0243 0.0616
Entamoeba histolytica hypothetical protein 0.024 0.0296 0.5254
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0017 0.0056
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0081 0.0078 0.0194
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.046 0.0595 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.0062 0.0157
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0309 0.039 0.0992
Loa Loa (eye worm) cytochrome P450 0.0025 0.0003 0.0007
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0025 0.0003 0.0001
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0344 0.0438 0.1118
Loa Loa (eye worm) cytochrome P450 family protein 0.0087 0.0088 0.0222
Brugia malayi jmjC domain containing protein 0.0037 0.002 0.0048
Echinococcus granulosus FTZ F1 alpha 0.0099 0.0104 0.0155
Loa Loa (eye worm) hypothetical protein 0.0281 0.0351 0.0897
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0009 0.0027
Giardia lamblia Grp94/Hsp90 0.0105 0.0112 0.3153
Mycobacterium ulcerans hypothetical protein 0.0121 0.0134 0.0336
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0019 0.0043
Echinococcus multilocularis mitogen activated protein kinase 3 0.0048 0.0034 0.0034
Plasmodium vivax proline--tRNA ligase, putative 0.0053 0.004 0.0105
Loa Loa (eye worm) voltage-gated potassium channel 0.0189 0.0226 0.0577
Echinococcus multilocularis ecdysone induced protein 78C 0.0099 0.0104 0.0104
Schistosoma mansoni adenoreceptor 0.0026 0.0003 0.0004
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0099 0.0104 0.0154
Echinococcus granulosus neuropeptide receptor 0.0026 0.0003 0.0005
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0032 0.0013 0.0042
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0007 0.0011
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0013 0.0027
Echinococcus multilocularis serotonin receptor 0.0026 0.0003 0.0003
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.011 0.0119 0.0298
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0059 0.0049 0.0049
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0045 0.003 0.007
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0108 0.0116 0.029
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0267 0.0332 0.0848
Entamoeba histolytica protein kinase, putative 0.0029 0.0009 0.015
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0128 0.0143 0.0143
Plasmodium vivax importin-beta 2, putative 0.004 0.0023 0.0058
Plasmodium falciparum heat shock protein 90, putative 0.036 0.046 0.1251
Loa Loa (eye worm) cytochrome c oxidase subunit II 0.0035 0.0016 0.0039
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0026 0.0003 0.0003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0267 0.0332 0.0496
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0069 0.0062 0.0157
Schistosoma mansoni smad1 5 8 and 0.0061 0.0051 0.0075
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0025 0.0003 0.0002
Schistosoma mansoni RAR-like nuclear receptor 0.0099 0.0104 0.0154
Schistosoma mansoni dihydroorotate dehydrogenase 0.0835 0.1107 0.165
Echinococcus granulosus glycine receptor subunit beta 0.0128 0.0143 0.0213
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Echinococcus granulosus somatostatin receptor 0.0026 0.0003 0.0005
Echinococcus granulosus Smad4 0.0061 0.0051 0.0077
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0012 0.0028
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Loa Loa (eye worm) CXXC zinc finger family protein 0.0103 0.0109 0.0277
Plasmodium falciparum protein MAM3, putative 0.0172 0.0203 0.0551
Schistosoma mansoni jumonji domain containing protein 0.0037 0.002 0.0028
Loa Loa (eye worm) hypothetical protein 0.0291 0.0365 0.0933
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Loa Loa (eye worm) acetylcholinesterase 1 0.1829 0.2463 0.6301
Loa Loa (eye worm) hypothetical protein 0.0034 0.0014 0.0035
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0059 0.0049 0.0073
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0108 0.0116 0.0291
Echinococcus multilocularis chromobox protein 1 0.0141 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0158 0.0184 0.0469
Onchocerca volvulus 0.0069 0.0062 0.0209
Brugia malayi mothers against decapentaplegic homolog 3 0.0027 0.0006 0.0012
Echinococcus granulosus Nuclear hormone receptor HR96 0.0047 0.0033 0.0049
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.0008 0.0025
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.023 0.0283 0.0717
Echinococcus granulosus tar DNA binding protein 0.0395 0.0507 0.0757
Echinococcus granulosus neuropeptide Y receptor 0.0026 0.0003 0.0005
Brugia malayi hypothetical protein 0.0026 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0086 0.0086 0.0219
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1285 0.1721 0.4399
Brugia malayi GnHR receptor homolog 0.0026 0.0003 0.0007
Onchocerca volvulus 0.0026 0.0003 0.0012
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0059 0.0049 0.0123
Echinococcus multilocularis neuropeptide Y receptor 0.0026 0.0003 0.0003
Schistosoma mansoni neuropeptide F-like receptor 0.0026 0.0003 0.0004
Loa Loa (eye worm) heat shock protein 90 0.0115 0.0126 0.032
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Onchocerca volvulus Cytochrome c oxidase subunit 2 homolog 0.0087 0.0087 0.0293
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0019 0.0043
Schistosoma mansoni peptidase Clp (S14 family) 0.046 0.0595 0.0887
Giardia lamblia Heat shock protein HSP 90-alpha 0.0115 0.0126 0.355
Onchocerca volvulus Protein ultraspiracle homolog 0.0099 0.0104 0.035
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0094 0.0097 0.0097
Echinococcus multilocularis neutral alpha glucosidase AB 0.0025 0.0002 0.0002
Echinococcus granulosus g protein coupled receptor 0.0026 0.0003 0.0005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.0003 0.0003
Mycobacterium tuberculosis Probable prolyl-tRNA synthetase ProS (proline--tRNA ligase) (PRORS) (global RNA synthesis factor) (proline translase) 0.0056 0.0045 0.0107
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0172 0.0203 0.0301
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0025 0.0003 0.0002
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0026 0.0003 0.0003
Brugia malayi Muscleblind-like protein 0.0197 0.0237 0.0604
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0028 0.0007 0.0007
Brugia malayi Dopamine receptor protein 2 0.0026 0.0003 0.0007
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0172 0.0203 0.0513
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0026 0.0003 0.0003
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0029 0.0009 0.0019
Schistosoma mansoni jumonji/arid domain-containing protein 0.0154 0.0178 0.0265
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.028 0.035 0.0522
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0108 0.0116 0.0291
Onchocerca volvulus 0.0026 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0128 0.0143 0.0143
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.011 0.0119 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0076 0.0254
Echinococcus multilocularis lysine specific demethylase 6a 0.0037 0.002 0.002
Schistosoma mansoni hypothetical protein 0.004 0.0023 0.0033
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0128 0.0143 0.0213
Brugia malayi tailless protein 0.0047 0.0033 0.0081
Loa Loa (eye worm) intermediate filament protein 0.0077 0.0074 0.0186
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0099 0.0104 0.0154
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0003 0.0004
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0201 0.0243 0.0619
Loa Loa (eye worm) hepatopoietin HPO2 0.0028 0.0007 0.0017
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0057 0.0047 0.0118
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0029 0.0009 0.0017
Mycobacterium ulcerans hypothetical protein 0.0172 0.0203 0.0512
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0059 0.0049 0.0123
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Echinococcus multilocularis integrin alpha 3 0.0058 0.0048 0.0048
Onchocerca volvulus 0.0026 0.0004 0.0015
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.003 0.007
Leishmania major glucose transporter/membrane transporter D2, putative 0.0029 0.0009 0.0016
Brugia malayi Glycosyl hydrolases family 31 protein 0.0111 0.012 0.0305
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.2889 0.3909 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0037 0.002 0.0044
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0128 0.0143 0.0363
Trichomonas vaginalis heat shock protein, putative 0.0115 0.0126 0.0422
Giardia lamblia Prolyl-tRNA synthetase 0.0048 0.0034 0.0953
Entamoeba histolytica acyl-coA synthetase, putative 0.0375 0.0481 0.8519
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0081
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.011 0.0119 0.0298
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0085 0.0085 0.0211
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0053 0.004 0.0059
Loa Loa (eye worm) hypothetical protein 0.004 0.0023 0.0057
Echinococcus granulosus hypothetical protein 0.0026 0.0003 0.0005
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0026 0.0003 0.0005
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.046 0.0595 0.1518
Schistosoma mansoni hypothetical protein 0.0928 0.1235 0.1841
Loa Loa (eye worm) hypothetical protein 0.1268 0.1698 0.4342
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0172 0.0203 0.5711
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0099 0.0104 0.0264
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0133 0.015 0.0381
Loa Loa (eye worm) hypothetical protein 0.046 0.0595 0.1521
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0019 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Toxoplasma gondii patched family protein 0.0026 0.0005 0.0006
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.023 0.0283 0.0717
Loa Loa (eye worm) hypothetical protein 0.0309 0.039 0.0996
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0835 0.1107 0.2828
Schistosoma mansoni zinc finger protein 0.0047 0.0033 0.0047
Echinococcus multilocularis acetylcholinesterase 0.1829 0.2463 0.2463
Plasmodium falciparum ataxin-2 like protein, putative 0.0088 0.0089 0.0243
Loa Loa (eye worm) nuclear receptor NHR-67 0.0047 0.0033 0.0081
Schistosoma mansoni smad 0.0027 0.0006 0.0007
Onchocerca volvulus 0.0069 0.0062 0.0209
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.0172 0.0203 0.0513
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0019 0.0043
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0025 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0081
Loa Loa (eye worm) hypothetical protein 0.0099 0.0104 0.0264
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0037 0.002 0.0044
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0069 0.0063 0.0156
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0037 0.002 0.0028
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0032 0.0013 0.0027
Toxoplasma gondii ABC1 family protein 0.0201 0.0243 0.0616
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Schistosoma mansoni steroid hormone receptor ad4bp 0.0099 0.0104 0.0154
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0028 0.0007 0.0013
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0172 0.0203 0.0512
Echinococcus multilocularis muscleblind protein 0.0197 0.0237 0.0237
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0025 0.0003 0.0002
Echinococcus granulosus glycine receptor subunit alpha 1 0.0128 0.0143 0.0213
Schistosoma mansoni nAChR subunit 0.0059 0.0049 0.0072
Schistosoma mansoni nAChR subunit 0.0128 0.0143 0.0211
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0025 0.0003 0.0002
Brugia malayi hypothetical protein 0.0059 0.0049 0.0123
Echinococcus granulosus smad 0.0061 0.0051 0.0077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0048
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0025 0.0003 0.0002
Trypanosoma cruzi chloride channel protein, putative 0.0172 0.0203 0.0513
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0053 0.004 0.004
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.0355 0.6285
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0048 0.0034 0.0086
Leishmania major acetyl-CoA synthetase, putative 0.011 0.0119 0.0299
Echinococcus multilocularis Niemann Pick C1 protein 0.0437 0.0564 0.0564
Trypanosoma brucei heat shock protein, putative 0.0115 0.0126 0.0317
Loa Loa (eye worm) hypothetical protein 0.0062 0.0053 0.0133
Echinococcus multilocularis lysine specific demethylase 5A 0.014 0.016 0.016
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0355 0.119
Schistosoma mansoni hypothetical protein 0.0181 0.0215 0.0319
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0057 0.0084
Mycobacterium ulcerans acyl-CoA synthetase 0.011 0.0119 0.0298
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0099 0.0104 0.0155
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0025 0.0002 0.0037
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0045 0.003 0.007
Trypanosoma brucei glucose transporter 2A 0.0029 0.0009 0.0016
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.2889 0.3909 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0033 0.0049
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0437 0.0564 1
Trypanosoma cruzi hypothetical protein, conserved 0.0201 0.0243 0.0616
Loa Loa (eye worm) chloride channel 3 0.0172 0.0203 0.0516
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.011 0.0119 0.0299
Echinococcus multilocularis sex peptide receptor 0.0026 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0025 0.0003 0.0002
Schistosoma mansoni chloride channel protein 0.0172 0.0203 0.0301
Echinococcus multilocularis nAChR subunit 0.0069 0.0062 0.0062
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.051 0.0664 0.1696
Loa Loa (eye worm) G-protein coupled receptor 0.0026 0.0003 0.0007
Schistosoma mansoni patched 1 0.0187 0.0224 0.0333
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0301 0.0379 0.0965
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0028 0.0007 0.0013
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0025 0.0003 0.0005
Brugia malayi Zinc finger, C2H2 type family protein 0.0326 0.0413 0.1055
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0025 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0003 0.0005
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0045 0.003 0.008
Trypanosoma cruzi GMP reductase 0.2889 0.3909 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0789 0.1045 0.2671
Brugia malayi hypothetical protein 0.0047 0.0033 0.0081
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0069 0.0062 0.0092
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.1372 0.184 0.4704
Echinococcus multilocularis ubiquitin specific protease 41 0.0028 0.0007 0.0007
Echinococcus granulosus integrin alpha 3 0.0058 0.0048 0.0071
Echinococcus granulosus beta LACTamase domain containing family member 0.0201 0.0243 0.0362
Mycobacterium tuberculosis Conserved protein 0.0172 0.0203 0.0512
Schistosoma mansoni methyl-cpg binding protein mbd 0.007 0.0064 0.0095
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0105 0.0112 0.028
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0025 0.0003 0.0002
Echinococcus granulosus JmjC domain containing protein 4 0.0037 0.002 0.0029
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.011 0.0119 0.0298
Brugia malayi Carboxylesterase family protein 0.0309 0.039 0.0996
Trichomonas vaginalis heat shock protein, putative 0.0081 0.0079 0.0265
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0003 0.0003
Brugia malayi Endoplasmin precursor 0.0115 0.0126 0.032
Plasmodium falciparum dihydroorotate dehydrogenase 0.0835 0.1107 0.3012
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0099 0.0104 0.0104
Toxoplasma gondii IMP dehydrogenas 0.2889 0.3909 1
Echinococcus multilocularis g protein coupled receptor 0.0026 0.0003 0.0003
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.011 0.0119 0.0298
Trypanosoma brucei protein kinase, putative 0.0048 0.0034 0.0082
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Plasmodium falciparum protein kinase 6 0.0401 0.0515 0.1402
Trichomonas vaginalis sucrase-isomaltase, putative 0.0025 0.0002 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0099 0.0104 0.0155
Echinococcus multilocularis survival motor neuron protein 1 0.1268 0.1698 0.1698
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0254 0.0314 0.0469
Plasmodium falciparum glutathione reductase 0.0129 0.0145 0.0393
Leishmania major hypothetical protein, conserved 0.0063 0.0054 0.0134
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0326 0.0413 0.1387
Brugia malayi acetyltransferase, GNAT family protein 0.0095 0.0099 0.0251
Echinococcus multilocularis 0.0025 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Trypanosoma brucei heat shock protein, putative 0.0115 0.0126 0.0317
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0172 0.0203 0.0203
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0029 0.0008 0.0008
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0041 0.0024 0.006
Toxoplasma gondii isocitrate dehydrogenase 0.0069 0.0063 0.0156
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0128 0.0143 0.0363
Echinococcus granulosus biogenic amine 5HT receptor 0.0026 0.0003 0.0005
Trypanosoma brucei heat shock protein, putative 0.0115 0.0126 0.0317
Echinococcus granulosus H:Cl exchange transporter 3 0.0172 0.0203 0.0302
Loa Loa (eye worm) hypothetical protein 0.0309 0.039 0.0996
Mycobacterium tuberculosis Conserved protein 0.0201 0.0243 0.0615
Onchocerca volvulus 0.0172 0.0203 0.0681
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0029 0.0009 0.0009
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0108 0.0116 0.0116
Schistosoma mansoni amine GPCR 0.0026 0.0003 0.0004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0267 0.0332 0.0495
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Schistosoma mansoni neuropeptide F-like receptor 0.0026 0.0003 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0344 0.0438 0.147
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0128 0.0143 0.0213
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0045 0.003 0.0069
Brugia malayi MH1 domain containing protein 0.0034 0.0014 0.0035
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0128 0.0143 0.0363
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.2889 0.3909 0.5832
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Treponema pallidum exodeoxyribonuclease (exoA) 0.0108 0.0116 0.191
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0099 0.0104 0.0264
Trichomonas vaginalis glucosylceramidase, putative 0.0238 0.0293 0.0983
Schistosoma mansoni amine GPCR 0.0026 0.0003 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0099 0.0104 0.0264
Brugia malayi MH2 domain containing protein 0.0027 0.0006 0.0012
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0129 0.0145 0.0364
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0037 0.0019 0.0019
Plasmodium vivax thioredoxin reductase, putative 0.0129 0.0145 0.0389
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0025 0.0003 0.0002
Brugia malayi CLC chloride channel protein 0.0172 0.0203 0.0516
Brugia malayi hypothetical protein 0.0026 0.0003 0.0007
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0172 0.0203 0.0301
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0267 0.0332 0.0495
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.024 0.0296 0.0442
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.0172 0.0203 0.0512
Toxoplasma gondii NADPH-glutathione reductase 0.0045 0.003 0.007
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0029 0.0009 0.002
Schistosoma mansoni terminal deoxycytidyl transferase 0.0033 0.0013 0.0018
Echinococcus granulosus peregrin 0.0032 0.0012 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0226 0.0277 0.0928
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0111 0.012 0.0305
Toxoplasma gondii HEAT repeat-containing protein 0.004 0.0023 0.0054
Leishmania major cytochrome p450-like protein 0.0025 0.0003 0.0003
Brugia malayi MH1 domain containing protein 0.0061 0.0051 0.0129
Brugia malayi Patched related family protein 10 0.0026 0.0005 0.001
Loa Loa (eye worm) RNA binding protein 0.0395 0.0507 0.1296
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.011 0.0119 0.0298
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.011 0.0119 0.0299
Brugia malayi Voltage gated chloride channel family protein 0.0172 0.0203 0.0516
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.003 0.007
Echinococcus multilocularis geminin 0.1719 0.2313 0.2313
Plasmodium falciparum ataxin-2 like protein, putative 0.0088 0.0089 0.0243
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0128 0.0143 0.0363
Onchocerca volvulus 0.0026 0.0003 0.0012
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0028 0.0007 0.0008
Echinococcus multilocularis thioredoxin glutathione reductase 0.0129 0.0145 0.0145
Brugia malayi Dopamine receptor protein 1 0.0026 0.0003 0.0007
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0025 0.0003 0.0002
Toxoplasma gondii CBS family protein 0.0172 0.0203 0.0513
Mycobacterium leprae conserved hypothetical protein 0.0172 0.0203 0.0512
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0128 0.0143 0.0143
Echinococcus granulosus importin subunit beta 1 0.004 0.0023 0.0035
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0128 0.0143 0.0211
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0071 0.0065 0.1154
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.035 0.0446 0.0446
Brugia malayi Serotonin receptor 0.0026 0.0003 0.0007
Brugia malayi Integrin alpha pat-2 precursor 0.0076 0.0072 0.0182
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0128 0.0143 0.0213
Schistosoma mansoni hypothetical protein 0.0181 0.0215 0.0319
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0026 0.0003 0.0004
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.011 0.0119 0.0298
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.011 0.0119 0.0298
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0045 0.003 0.007
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0059 0.0049 0.0049
Schistosoma mansoni acetylcholine receptor-related 0.0059 0.0049 0.0072
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0059 0.0049 0.0123
Plasmodium vivax SET domain protein, putative 0.028 0.035 0.0949
Trypanosoma cruzi major cysteine proteinase, putative 0.0029 0.0008 0.0016
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0108 0.0116 0.0291
Plasmodium vivax heat shock protein 86, putative 0.0115 0.0126 0.0338
Echinococcus multilocularis peregrin 0.0032 0.0012 0.0012
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.011 0.0119 0.0298
Echinococcus granulosus integrin alpha ps 0.0034 0.0015 0.0022
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.011 0.0119 0.0298
Echinococcus multilocularis microtubule associated protein 2 0.4937 0.6702 0.6702
Schistosoma mansoni protein kinase 0.0029 0.0009 0.0012
Entamoeba histolytica hypothetical protein 0.024 0.0296 0.5254
Mycobacterium ulcerans acetyl-CoA synthetase 0.011 0.0119 0.0298
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0013 0.0028
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0026 0.0003 0.0007
Echinococcus multilocularis acetylcholinesterase 0.1829 0.2463 0.2463
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Brugia malayi Niemann-Pick C1 protein precursor 0.0437 0.0564 0.1442
Loa Loa (eye worm) hypothetical protein 0.0309 0.039 0.0996
Entamoeba histolytica Ran family GTPase 0.0029 0.0009 0.0153
Brugia malayi nuclear hormone receptor family member nhr-6 0.0047 0.0033 0.0081
Brugia malayi Patched related family protein 12 0.0026 0.0005 0.001
Leishmania major cytochrome p450-like protein 0.0025 0.0003 0.0003
Echinococcus granulosus neutral alpha glucosidase AB 0.0025 0.0002 0.0003
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0095 0.0099 0.0146
Plasmodium falciparum glutathione reductase 0.0045 0.003 0.008
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Trypanosoma brucei PAB1-binding protein , putative 0.0088 0.0089 0.0223
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0105 0.0112 0.0281
Leishmania major importin beta-1 subunit, putative 0.0032 0.0013 0.0027
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.0172 0.0203 0.0513
Schistosoma mansoni hypothetical protein 0.0427 0.0551 0.0821
Echinococcus granulosus g-protein coupled receptor 0.0026 0.0003 0.0005
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0024 0.0036
Trypanosoma brucei heat shock protein, putative 0.0115 0.0126 0.0317
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0071 0.0065 0.0065
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0025 0.0003 0.0002
Onchocerca volvulus 0.0026 0.0003 0.0012
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0109 0.0117 0.0294
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0003 0.0005
Trypanosoma cruzi chloride channel protein, putative 0.0172 0.0203 0.0513
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0025 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Brugia malayi G-protein coupled receptor 0.0026 0.0003 0.0007
Trypanosoma brucei glucose transporter 1E 0.0029 0.0009 0.0016
Schistosoma mansoni glucose transport protein 0.0094 0.0097 0.0144
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0029 0.0008 0.0011
Toxoplasma gondii histone lysine methyltransferase SET1 0.0217 0.0265 0.0672
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0094 0.0097 0.0145
Brugia malayi intermediate filament protein 0.0077 0.0074 0.0186
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0034 0.0015 0.0032
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0128 0.0143 0.0143
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0267 0.0332 0.0495
Echinococcus granulosus sex peptide receptor 0.0026 0.0003 0.0005
Echinococcus granulosus mothers against decapentaplegic 2 0.0027 0.0006 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0303 0.0382 0.0568
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0099 0.0104 0.0264
Onchocerca volvulus Protein patched homolog 0.0026 0.0005 0.0016
Trichomonas vaginalis endoplasmin, putative 0.0081 0.0079 0.0265
Echinococcus multilocularis sterol regulatory element binding protein 0.0187 0.0224 0.0224
Brugia malayi G protein-coupled receptor F59B2.13 0.0026 0.0003 0.0007
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0029 0.0009 0.0023
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0172 0.0203 0.5711
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0099 0.0104 0.0264
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Echinococcus multilocularis tar DNA binding protein 0.0395 0.0507 0.0507
Trichomonas vaginalis antibiotic synthetase, putative 0.011 0.0119 0.0398
Brugia malayi Steroid receptor seven-up type 2 0.0099 0.0104 0.0264
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0128 0.0143 0.0363
Echinococcus granulosus neuropeptide Y receptor 0.0026 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.0047
Loa Loa (eye worm) hypothetical protein 0.017 0.02 0.051
Brugia malayi Serotonin receptor 0.0026 0.0003 0.0007
Echinococcus multilocularis Niemann Pick C1 protein 0.0624 0.082 0.082
Schistosoma mansoni hypothetical protein 0.0025 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0029 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Toxoplasma gondii facilitative glucose transporter GT1 0.0094 0.0097 0.0243
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0025 0.0003 0.0002
Brugia malayi hypothetical protein 0.0309 0.039 0.0996
Echinococcus multilocularis beta LACTamase domain containing family member 0.0201 0.0243 0.0243
Brugia malayi Bromodomain containing protein 0.0316 0.04 0.1022
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0008 0.0011
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0443 0.0573 0.0854
Schistosoma mansoni hypothetical protein 0.0026 0.0003 0.0004
Echinococcus granulosus snurportin 1 0.0427 0.0551 0.0822
Echinococcus multilocularis hyperpolarization activated cyclic 0.0029 0.0008 0.0008
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0094 0.0097 0.0097
Plasmodium vivax threonine--tRNA ligase, putative 0.0025 0.0003 0.0002
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0301 0.0379 0.0965
Echinococcus multilocularis cpg binding protein 0.0117 0.0128 0.0128
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0026 0.0003 0.0004
Schistosoma mansoni thyroid hormone receptor 0.0474 0.0615 0.0916
Toxoplasma gondii patched family protein 0.0026 0.0005 0.0006
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0109 0.0117 0.0294
Trypanosoma cruzi PAB1-binding protein , putative 0.0088 0.0089 0.0223
Brugia malayi loechrig isoform VII 0.0172 0.0203 0.0516
Plasmodium vivax acetyl-CoA synthetase, putative 0.011 0.0119 0.0319
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.024 0.0296 0.0296
Brugia malayi nuclear receptor NHR-88 0.0047 0.0033 0.0081
Echinococcus granulosus dnaJ subfamily B 0.0928 0.1235 0.1843
Echinococcus granulosus jumonji domain containing protein 0.0028 0.0007 0.001
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0281 0.0351 0.0892
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0294 0.037 0.0941
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0025 0.0003 0.0002
Wolbachia endosymbiont of Brugia malayi cytochrome c oxidase, subunit 2 0.0287 0.0361 0.0917
Echinococcus granulosus General substrate transporter 0.0081 0.0079 0.0118
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0025 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.0539 0.0704 0.105
Schistosoma mansoni hypothetical protein 0.1719 0.2313 0.345
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0128 0.0143 0.0363
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0057 0.0138
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0003 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0003 0.0003
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0029 0.0009 0.002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0069 0.0063 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0045 0.0149
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0099 0.0104 0.0104
Brugia malayi Carboxylesterase family protein 0.0309 0.039 0.0996
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0019 0.0043
Loa Loa (eye worm) oxidoreductase 0.011 0.0119 0.0302
Brugia malayi excitatory GABA receptor EXP-1A 0.0128 0.0143 0.0363
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0026 0.0003 0.0004
Brugia malayi Carboxylesterase family protein 0.0309 0.039 0.0996
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Toxoplasma gondii Erv1 / Alr family protein 0.0028 0.0007 0.0013
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0025 0.0063
Brugia malayi CXXC zinc finger family protein 0.0103 0.0109 0.0277
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0048 0.0034 0.0082
Loa Loa (eye worm) hypothetical protein 0.0309 0.039 0.0996
Schistosoma mansoni phosphatidylserine receptor 0.0037 0.002 0.0028
Leishmania major cathepsin L-like protease 0.0037 0.0019 0.0043
Trichomonas vaginalis penicillin-binding protein, putative 0.0201 0.0243 0.0815
Trichomonas vaginalis alpha-glucosidase, putative 0.0025 0.0002 0.0006
Brugia malayi heat shock protein 90 0.0115 0.0126 0.032
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0026 0.0003 0.0007
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0047 0.0033 0.0047
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0395 0.0507 0.1296
Loa Loa (eye worm) acetylcholine receptor protein 0.0059 0.0049 0.0123
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0025 0.0003 0.0002
Schistosoma mansoni jumonji/arid domain-containing protein 0.0154 0.0178 0.0265
Schistosoma mansoni amine GPCR 0.0026 0.0003 0.0004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0045 0.003 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0053 0.004 0.0098
Brugia malayi ancient conserved domain protein 4 0.0172 0.0203 0.0516
Toxoplasma gondii hypothetical protein 0.0026 0.0005 0.0006
Echinococcus granulosus 7TM GPCR rhodopsin 0.0026 0.0003 0.0005
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0026 0.0003 0.0007
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0026 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.1829 0.2463 0.6301
Trypanosoma brucei heat shock protein, putative 0.0115 0.0126 0.0317
Loa Loa (eye worm) hypothetical protein 0.0099 0.0104 0.0264
Onchocerca volvulus 0.0158 0.0184 0.0619
Mycobacterium leprae putative cytochrome p450 0.0025 0.0003 0.0002
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0026 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0099 0.0104 0.0264
Entamoeba histolytica acyl-CoA synthetase, putative 0.0375 0.0481 0.8519
Brugia malayi Isocitrate dehydrogenase 0.0069 0.0063 0.016
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0033 0.0013 0.0031
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.003 0.007
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0201 0.0243 0.0615
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0048 0.0034 0.0082
Schistosoma mansoni lamin 0.0077 0.0074 0.0108
Loa Loa (eye worm) hypothetical protein 0.0281 0.0351 0.0897
Loa Loa (eye worm) chloride channel protein 7 0.0172 0.0203 0.0516
Loa Loa (eye worm) hypothetical protein 0.0029 0.0008 0.0018
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0033 0.0013 0.0013
Onchocerca volvulus Cytochrome c oxidase subunit 2 homolog 0.0087 0.0087 0.0293
Echinococcus granulosus neuroligin 0.0309 0.039 0.0582
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Trypanosoma cruzi ISWI complex protein 0.0063 0.0054 0.0134
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0035 0.0016 0.004
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0026 0.0003 0.0004
Schistosoma mansoni smad1 5 8 and 0.0061 0.0051 0.0075
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0281 0.0351 0.0892
Loa Loa (eye worm) hypothetical protein 0.023 0.0282 0.0719
Loa Loa (eye worm) melatonin receptor type 1A 0.0026 0.0003 0.0007
Entamoeba histolytica deoxycytidyl transferase, putative 0.0033 0.0013 0.0228
Echinococcus multilocularis integrin alpha ps 0.0034 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0187 0.0224 0.0572
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0025 0.0003 0.0002
Leishmania major threonyl-tRNA synthetase, putative 0.0025 0.0003 0.0001
Giardia lamblia DINP protein human, muc B family 0.0033 0.0013 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0099 0.0104 0.0264
Schistosoma mansoni hypothetical protein 0.025 0.0309 0.046
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0048 0.0034 0.0082
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0309 0.039 0.0581
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0059 0.0049 0.0123
Brugia malayi hypothetical protein 0.0026 0.0005 0.001
Brugia malayi hypothetical protein 0.024 0.0296 0.0757
Leishmania major 4-coumarate:coa ligase-like protein 0.0375 0.0481 0.1225
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0128 0.0143 0.0363
Loa Loa (eye worm) hypothetical protein 0.0201 0.0243 0.0619
Leishmania major guanosine monophosphate reductase 0.2889 0.3909 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0061 0.0051 0.0129
Leishmania major chloride channel protein, putative 0.0172 0.0203 0.0513
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Brugia malayi hypothetical protein 0.1268 0.1698 0.4342
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0019 0.0043
Brugia malayi Importin beta-1 subunit 0.004 0.0023 0.0057
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0128 0.0143 0.0213
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.0172 0.0203 0.0512
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0047 0.0033 0.0109
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0025 0.0003 0.0003
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0053 0.004 0.0098
Brugia malayi AMP-binding enzyme family protein 0.011 0.0119 0.0302
Brugia malayi Carboxylesterase family protein 0.1829 0.2463 0.6301
Toxoplasma gondii propionate-CoA ligase 0.011 0.0119 0.0299
Toxoplasma gondii glycyl-tRNA synthetase 0.0025 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Toxoplasma gondii heat shock protein 90, putative 0.0115 0.0126 0.0317
Brugia malayi MH2 domain containing protein 0.089 0.1183 0.3024
Brugia malayi nuclear receptor RXR 0.0047 0.0033 0.0081
Loa Loa (eye worm) hypothetical protein 0.0201 0.0243 0.0619
Brugia malayi Cytochrome P450 family protein 0.0032 0.0012 0.0028
Trichomonas vaginalis spcc417.12 protein, putative 0.0309 0.039 0.1309
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Plasmodium falciparum importin beta, putative 0.004 0.0023 0.0063
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Onchocerca volvulus 0.2206 0.2976 1
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.0003 0.0004
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0025 0.0003 0.0001
Onchocerca volvulus 0.011 0.0119 0.04
Leishmania major 4-coumarate:coa ligase-like protein 0.0375 0.0481 0.1225
Trypanosoma cruzi cruzipain precursor, putative 0.0037 0.0019 0.0043
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0036 0.0017 0.0026
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0094 0.0097 0.0097
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.002 0.0048
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0039 0.0022 0.0052
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0172 0.0203 0.0302
Brugia malayi jmjC domain containing protein 0.0037 0.002 0.0048
Schistosoma mansoni biogenic amine (5HT) receptor 0.0026 0.0003 0.0004
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.0172 0.0203 0.0512
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0048 0.0034 0.0082
Echinococcus multilocularis fmrfamide receptor 0.0026 0.0003 0.0003
Brugia malayi nuclear receptor NHR-67 0.0047 0.0033 0.0081
Brugia malayi Heterochromatin protein 1 0.0141 0.016 0.0408
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0294 0.037 0.0941
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0045 0.003 0.0069
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Trypanosoma cruzi chloride channel protein, putative 0.0172 0.0203 0.0513
Brugia malayi AMP-binding enzyme family protein 0.011 0.0119 0.0302
Loa Loa (eye worm) CHromoDomain protein family member 0.0037 0.0019 0.0046
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0025 0.0003 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0025 0.0003 0.0002
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0172 0.0203 0.0512
Trichomonas vaginalis conserved hypothetical protein 0.0187 0.0224 0.0752
Onchocerca volvulus 0.0309 0.039 0.1311
Brugia malayi neuropeptide F receptor 0.0026 0.0003 0.0007
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0182 0.0216 0.0323
Loa Loa (eye worm) hypothetical protein 0.0048 0.0034 0.0085
Giardia lamblia Heat shock protein HSP 90-alpha 0.0097 0.0101 0.2857
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0025 0.0003 0.0002
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.2889 0.3909 1
Plasmodium vivax proline--tRNA ligase, putative 0.0066 0.0058 0.0153
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0265 0.033 0.0839
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0045 0.003 0.0076
Toxoplasma gondii exonuclease III APE 0.0108 0.0116 0.0291
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0267 0.0332 0.0332
Mycobacterium ulcerans transmembrane cytochrome C oxidase (subunit II) CtaC 0.0087 0.0087 0.0217
Loa Loa (eye worm) hypothetical protein 0.0053 0.004 0.0101
Echinococcus multilocularis expressed conserved protein 0.041 0.0528 0.0528
Schistosoma mansoni myosin xvIII 0.0026 0.0003 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0024 0.0035
Leishmania major glucose transporter, lmgt1 0.0029 0.0009 0.0016
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0108 0.0116 0.3262
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0026 0.0003 0.0007
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0201 0.0242 0.0361
Schistosoma mansoni biogenic amine (5HT) receptor 0.0026 0.0003 0.0004
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0201 0.0243 0.0615
Schistosoma mansoni biogenic amine receptor 0.0026 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0201 0.0243 0.0619
Brugia malayi hypothetical protein 0.0026 0.0005 0.001
Schistosoma mansoni heat shock protein 0.0115 0.0126 0.0187
Mycobacterium ulcerans esterase/lipase LipP 0.0201 0.0243 0.0615
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0081
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0201 0.0242 0.0618
Echinococcus granulosus nAChR subunit 0.0069 0.0062 0.0093
Echinococcus multilocularis smad 0.0061 0.0051 0.0051
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0045 0.003 0.0069
Brugia malayi Cyclic-nucleotide gated cation channel 0.0029 0.0008 0.0018
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0095 0.0099 0.0099
Brugia malayi Cytochrome P450 family protein 0.0032 0.0012 0.0028
Echinococcus granulosus dna polymerase eta 0.0033 0.0013 0.0019
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0048 0.0034 0.0082
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Entamoeba histolytica heat shock protein 90, putative 0.0115 0.0126 0.2231
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0026 0.0003 0.0003
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.2889 0.3909 1
Echinococcus granulosus lamin dm0 0.0077 0.0074 0.011
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0081
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0024 0.0035
Brugia malayi jmjC domain containing protein 0.0037 0.002 0.0048
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0094 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Echinococcus multilocularis orexin receptor type 2 0.0026 0.0003 0.0003
Loa Loa (eye worm) patched family protein 0.0026 0.0005 0.001
Onchocerca volvulus 0.0259 0.0321 0.108
Schistosoma mansoni hypothetical protein 0.1719 0.2313 0.345
Brugia malayi hypothetical protein 0.0403 0.0518 0.1323
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0025 0.0003 0.0002
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0028 0.0007 0.001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0474 0.0615 0.0615
Trypanosoma brucei importin beta-1 subunit, putative 0.004 0.0023 0.0054
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0053 0.004 0.0101
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0172 0.0203 0.0203
Trichomonas vaginalis glucosylceramidase, putative 0.0344 0.0438 0.147
Schistosoma mansoni glucose transport protein 0.0094 0.0097 0.0144
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0006 0.0012
Schistosoma mansoni protein phosphatase 2C 0.0037 0.002 0.0028
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0028 0.0007 0.0015
Trypanosoma brucei unspecified product 0.0033 0.0013 0.0028
Schistosoma mansoni opsin-like receptor 0.0026 0.0003 0.0004
Mycobacterium ulcerans transcriptional regulator 0.0172 0.0203 0.0512
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Brugia malayi hypothetical protein 0.0026 0.0005 0.001
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0525 0.0684 0.1746
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0028 0.0007 0.0007
Trypanosoma brucei THT1 - hexose transporter, putative 0.0029 0.0009 0.0016
Echinococcus multilocularis prolyl tRNA synthetase, mitochondrial 0.0066 0.0058 0.0058
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0095 0.0098 0.0244
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0048 0.0034 0.0112
Brugia malayi putative neuropeptide receptor 0.0026 0.0003 0.0007
Echinococcus granulosus peptide allatostatin:somatostatin 0.0026 0.0003 0.0005
Loa Loa (eye worm) MH1 domain-containing protein 0.0061 0.0051 0.0129
Loa Loa (eye worm) histone methyltransferase 0.0042 0.0026 0.0065
Trypanosoma cruzi Heat shock protein 83, putative 0.0115 0.0126 0.0317
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Brugia malayi hypothetical protein 0.0059 0.0049 0.0123
Schistosoma mansoni alpha-glucosidase 0.0096 0.0099 0.0146
Echinococcus multilocularis neuropeptide receptor 0.0026 0.0003 0.0003
Schistosoma mansoni lipoxygenase 0.0084 0.0084 0.0123
Schistosoma mansoni glycyl-tRNA synthetase 0.0025 0.0003 0.0003
Brugia malayi conserved hypotetical protein 0.0047 0.0033 0.0081
Trichomonas vaginalis glucosylceramidase, putative 0.0226 0.0277 0.0928
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0172 0.0203 0.0203
Schistosoma mansoni cytochrome-c oxidase 0.0087 0.0087 0.0129
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0099 0.0104 0.035
Trypanosoma brucei heat shock protein 84, putative 0.0071 0.0065 0.0161
Onchocerca volvulus 0.0087 0.0087 0.0293
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.0172 0.0203 0.0513
Loa Loa (eye worm) hypothetical protein 0.0789 0.1045 0.2671
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0338 0.0429 0.0641
Loa Loa (eye worm) bromodomain containing protein 0.0075 0.0071 0.0179
Trichomonas vaginalis mercuric reductase, putative 0.0045 0.003 0.0098
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0128 0.0143 0.0363
Echinococcus granulosus mothers against decapentaplegic 6 0.0027 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0081 0.0078 0.0199
Schistosoma mansoni importin beta-1 0.004 0.0023 0.0033
Trypanosoma cruzi heat shock protein 85, putative 0.0115 0.0126 0.0317
Schistosoma mansoni alpha-glucosidase 0.0096 0.0099 0.0146
Loa Loa (eye worm) GABA receptor subunit 0.0069 0.0062 0.0157
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0026 0.0003 0.0005
Loa Loa (eye worm) patched family protein 0.0026 0.0005 0.001
Mycobacterium ulcerans DNA polymerase IV 0.0033 0.0013 0.0027
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0128 0.0143 0.0363
Loa Loa (eye worm) hypothetical protein 0.0053 0.004 0.0101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0099 0.0104 0.0264
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0003 0.0005
Mycobacterium tuberculosis Probable lipase LipD 0.0201 0.0243 0.0615
Echinococcus multilocularis calcium dependent protein kinase 0.0027 0.0006 0.0006
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0338 0.0429 0.1441
Schistosoma mansoni smad1 5 8 and 0.0061 0.0051 0.0075
Onchocerca volvulus 0.0026 0.0005 0.0016
Brugia malayi Nuclear hormone receptor E75 0.0047 0.0033 0.0081
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0019 0.0043
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0033 0.0047
Echinococcus granulosus neuropeptide FF receptor 2 0.0026 0.0003 0.0005
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.1201 0.1606 0.4108
Loa Loa (eye worm) hypothetical protein 0.0106 0.0113 0.0288
Echinococcus multilocularis integrin alpha ps 0.0034 0.0015 0.0015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0201 0.0243 0.0361
Echinococcus granulosus dna polymerase kappa 0.0033 0.0013 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0099 0.0104 0.0264
Onchocerca volvulus 0.011 0.0119 0.04
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0375 0.0481 0.1224
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.003 0.007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0201 0.0242 0.0242
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0037 0.0019 0.0027
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0006 0.0012
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0327 0.0415 0.1055
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0081
Chlamydia trachomatis CBS domain-containing protein 0.0172 0.0203 0.3375
Brugia malayi nuclear receptor RXR 0.0053 0.004 0.0101
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0029 0.0009 0.0019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0099 0.0104 0.0155
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0025 0.0003 0.0002
Echinococcus granulosus alpha 1A adrenergic receptor 0.0026 0.0003 0.0005
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0327 0.0415 0.1055
Brugia malayi nuclear hormone receptor 0.0047 0.0033 0.0081
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.1517 0.2037 0.5209
Onchocerca volvulus Putative GMP reductase 0.1201 0.1606 0.5396
Brugia malayi hypothetical protein 0.0586 0.0768 0.1963
Loa Loa (eye worm) hypothetical protein 0.0375 0.0481 0.1228
Loa Loa (eye worm) hypothetical protein 0.0172 0.0203 0.0516
Echinococcus granulosus sterol regulatory element binding protein 0.0187 0.0224 0.0335
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0045 0.003 0.0076
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0201 0.0243 0.0619
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0081
Echinococcus granulosus acetylcholinesterase 0.1829 0.2463 0.3676
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0008 0.0011
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0026 0.0003 0.0005
Schistosoma mansoni integrin beta subunit 0.0091 0.0093 0.0138
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0835 0.1107 0.283
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Trichomonas vaginalis ran, putative 0.0029 0.0009 0.0028
Trypanosoma cruzi heat shock protein 90, putative 0.0052 0.004 0.0096
Loa Loa (eye worm) hypothetical protein 0.0069 0.0062 0.0157
Mycobacterium ulcerans hypothetical protein 0.0172 0.0203 0.0512
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0029 0.0009 0.0009
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0045 0.003 0.007
Echinococcus multilocularis heat shock protein 0.0115 0.0126 0.0126
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0128 0.0143 0.0211
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0059 0.0049 0.0123
Onchocerca volvulus 0.0128 0.0143 0.0479
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0046 0.0032 0.0105
Trichomonas vaginalis importin beta-1, putative 0.0032 0.0013 0.0042
Echinococcus granulosus phd:f box containing protein 0.0037 0.002 0.0029
Giardia lamblia Hypothetical protein 0.0172 0.0203 0.5711
Schistosoma mansoni Smad4 0.0027 0.0006 0.0007
Echinococcus multilocularis snurportin 1 0.0427 0.0551 0.0551
Brugia malayi Pre-SET motif family protein 0.028 0.035 0.0894
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0057 0.0083
Schistosoma mansoni voltage-gated potassium channel 0.0145 0.0166 0.0246
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0375 0.0481 0.1224
Plasmodium vivax cytochrome c oxidase subunit 2, putative 0.0087 0.0087 0.0232
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 0.0835 0.1107 0.2827
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.011 0.0119 0.0299
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0008 0.0011
Schistosoma mansoni bromodomain containing protein 0.0268 0.0334 0.0498
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0099 0.0104 0.0264
Schistosoma mansoni hypothetical protein 0.0181 0.0215 0.0319
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0084 0.0084 0.0084
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0182 0.0216 0.0216
Onchocerca volvulus Cytochrome c oxidase subunit 2 homolog 0.0087 0.0087 0.0293
Echinococcus granulosus zinc finger protein 0.0088 0.0089 0.0133
Schistosoma mansoni chromobox protein 0.0141 0.016 0.0238
Schistosoma mansoni transcription factor LCR-F1 0.024 0.0296 0.0441
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0025 0.0003 0.0002
Echinococcus granulosus dro:myosuppressin receptor 0.0026 0.0003 0.0005
Echinococcus granulosus glycine receptor subunit alpha 1 0.0128 0.0143 0.0213
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0069 0.0062 0.0157
Loa Loa (eye worm) sugar transporter 0.0094 0.0097 0.0247
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.011 0.0119 0.0298
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0033 0.0047
Loa Loa (eye worm) hypothetical protein 0.0172 0.0203 0.0516
Leishmania major protein kinase, putative 0.0029 0.0009 0.0016
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.2889 0.3909 0.3909
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0309 0.039 0.0581
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0026 0.0003 0.0005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0046 0.0032 0.0105
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.1201 0.1606 0.4108
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0034 0.0114
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0029 0.0009 0.002
Chlamydia trachomatis proline--tRNA ligase 0.0085 0.0085 0.1389
Schistosoma mansoni heat shock protein 0.0071 0.0065 0.0096
Onchocerca volvulus Protein patched homolog 0.0026 0.0005 0.0016
Loa Loa (eye worm) cytochrome oxidase subunit 2 0.0052 0.004 0.01
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.004 0.0101
Loa Loa (eye worm) hypothetical protein 0.035 0.0446 0.1139
Onchocerca volvulus 0.0026 0.0003 0.0012
Leishmania major 4-coumarate:coa ligase-like protein 0.0375 0.0481 0.1225
Echinococcus granulosus hyperpolarization activated cyclic 0.0029 0.0008 0.0012
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0042 0.0026 0.0026
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0025 0.0003 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0267 0.0332 0.0496
Schistosoma mansoni nAChR subunit 0.0059 0.0049 0.0072
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0071 0.0065 0.0219
Schistosoma mansoni lamin 0.0077 0.0074 0.0108
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0047 0.0033 0.0033
Schistosoma mansoni cpg binding protein 0.0117 0.0128 0.0189
Loa Loa (eye worm) integrin alpha pat-2 0.0117 0.0128 0.0325
Schistosoma mansoni intermediate filament proteins 0.0077 0.0074 0.0108
Echinococcus multilocularis jumonji domain containing 1A 0.0037 0.002 0.002
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0254 0.0314 0.0314
Echinococcus multilocularis peptidase Clp (S14 family) 0.0301 0.0379 0.0379
Brugia malayi Thioredoxin reductase 0.0129 0.0145 0.0368
Schistosoma mansoni hypothetical protein 0.0063 0.0054 0.008
Trichomonas vaginalis glucosylceramidase, putative 0.0238 0.0293 0.0983
Trichomonas vaginalis D-aminoacylase, putative 0.0201 0.0243 0.0815
Brugia malayi glutathione reductase 0.0129 0.0145 0.0368
Echinococcus multilocularis heat shock protein 90 0.0097 0.0101 0.0101
Schistosoma mansoni nuclear receptor 0.0047 0.0033 0.0047
Leishmania major glucose transporter, lmgt2 0.0029 0.0009 0.0016
Mycobacterium leprae PROBABLE TRANSMEMBRANE CYTOCHROME C OXIDASE (SUBUNIT II) CTAC 0.0052 0.004 0.0095
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.011 0.0119 0.0299
Brugia malayi Melatonin receptor type 1A 0.0026 0.0003 0.0007
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0009 0.0016
Entamoeba histolytica protein kinase, putative 0.0029 0.0009 0.015
Echinococcus multilocularis Smad4 0.0061 0.0051 0.0051
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0128 0.0143 0.0363
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0045 0.003 0.007
Echinococcus multilocularis mothers against decapentaplegic 6 0.0027 0.0006 0.0006
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0069 0.0063 0.0093
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0045 0.003 0.0456
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Onchocerca volvulus Cytochrome c oxidase subunit 2 homolog 0.0087 0.0087 0.0293
Plasmodium falciparum JmjC domain-containing protein, putative 0.0037 0.002 0.0053
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0046 0.0032 0.0105
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0012 0.0028
Brugia malayi MH2 domain containing protein 0.0061 0.0051 0.0129
Trypanosoma cruzi heat shock protein, putative 0.0071 0.0065 0.0161
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.0172 0.0203 0.0512
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0053 0.004 0.0098
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0025 0.0003 0.0043
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.0003 0.0005
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0009 0.0027
Treponema pallidum hemolysin (tlyC) 0.0172 0.0203 0.3375
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Schistosoma mansoni alpha-1 adrenergic receptor 0.0026 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Schistosoma mansoni hypothetical protein 0.0181 0.0215 0.0319
Echinococcus multilocularis dna polymerase eta 0.0033 0.0013 0.0013
Schistosoma mansoni nuclear hormone receptor 0.0099 0.0104 0.0154
Plasmodium falciparum heat shock protein 90 0.0115 0.0126 0.0342
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0025 0.0003 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0034 0.0114
Brugia malayi Probable ClpP-like protease 0.046 0.0595 0.1521
Echinococcus multilocularis neuropeptides capa receptor 0.0026 0.0003 0.0003
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0047 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.011 0.0119 0.0299
Schistosoma mansoni cytochrome c oxidase subunit II 0.0235 0.029 0.0431
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0029 0.0009 0.0017
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0026 0.0003 0.0007
Trypanosoma brucei ISWI complex protein 0.0063 0.0054 0.0134
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0026 0.0003 0.0003
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0033 0.0013 0.0019
Leishmania major hypothetical protein, conserved 0.0088 0.0089 0.0223
Echinococcus granulosus geminin 0.1719 0.2313 0.3451
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0045 0.003 0.007
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0036 0.0017 0.0017
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0029 0.0008 0.0012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0069 0.0063 0.0063
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.2718 0.3675 1
Schistosoma mansoni hypothetical protein 0.0259 0.0321 0.0478
Onchocerca volvulus Bile acid receptor homolog 0.0099 0.0104 0.035
Plasmodium falciparum proline--tRNA ligase 0.0053 0.004 0.0109
Schistosoma mansoni endoplasmin 0.0115 0.0126 0.0187
Schistosoma mansoni nAChR subunit 0.0128 0.0143 0.0211
Schistosoma mansoni ap endonuclease 0.0108 0.0116 0.0171
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0035 0.0016 0.0036
Loa Loa (eye worm) hypothetical protein 0.0069 0.0062 0.0157
Brugia malayi ecdysone receptor 0.0047 0.0033 0.0081
Trichomonas vaginalis alpha-glucosidase, putative 0.0025 0.0002 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0226 0.0277 0.0928
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0009 0.0016
Echinococcus granulosus lysine specific demethylase 5A 0.0154 0.0178 0.0266
Brugia malayi cytochrome c oxidase subunit II 0.0035 0.0016 0.0039
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Onchocerca volvulus 0.0403 0.0518 0.1739
Schistosoma mansoni jumonji domain containing protein 0.0168 0.0198 0.0294
Echinococcus multilocularis g-protein coupled receptor 0.0026 0.0003 0.0003
Brugia malayi hypothetical protein 0.0026 0.0003 0.0007
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0033 0.0013 0.0032
Echinococcus granulosus integrin beta 2 0.0115 0.0125 0.0187
Loa Loa (eye worm) hypothetical protein 0.0375 0.0481 0.1228
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0057 0.0138
Loa Loa (eye worm) isocitrate dehydrogenase 0.0069 0.0063 0.016
Loa Loa (eye worm) hypothetical protein 0.0042 0.0026 0.0064
Schistosoma mansoni amine GPCR 0.0026 0.0003 0.0004
Schistosoma mansoni neuroligin 3 (S09 family) 0.0309 0.039 0.0581
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0281 0.0351 0.0897
Loa Loa (eye worm) hypothetical protein 0.0201 0.0243 0.0619
Trypanosoma brucei acetyl-CoA synthetase, putative 0.011 0.0119 0.0299
Brugia malayi protein C24B5.3 0.0026 0.0005 0.001
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.011 0.0119 0.0299
Loa Loa (eye worm) acetyltransferase 0.0095 0.0099 0.0251
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.046 0.0595 0.1517
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0003 0.0004
Loa Loa (eye worm) patched family protein 0.0026 0.0005 0.001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.0003 0.0004
Loa Loa (eye worm) LGC-31 protein 0.0128 0.0143 0.0363
Trichomonas vaginalis heat shock protein, putative 0.0105 0.0112 0.0374
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0069 0.0062 0.0157
Loa Loa (eye worm) patched family protein 0.0026 0.0005 0.001
Echinococcus multilocularis BC026374 protein (S09 family) 0.0309 0.039 0.039
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0026 0.0003 0.0004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.0007 0.002
Toxoplasma gondii Erv1 / Alr family protein 0.0028 0.0007 0.0013
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0029 0.0009 0.002
Brugia malayi nuclear hormone receptor family member odr-7 0.0047 0.0033 0.0081
Entamoeba histolytica heat shock protein 90, putative 0.0115 0.0126 0.2231
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0128 0.0143 0.0211
Brugia malayi hypothetical protein 0.0059 0.0049 0.0123
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0128 0.0143 0.0363
Plasmodium vivax JmjC domain containing protein 0.0037 0.002 0.0048
Echinococcus granulosus neuropeptides capa receptor 0.0026 0.0003 0.0005
Trichomonas vaginalis chromobox protein, putative 0.0141 0.016 0.0537
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0128 0.0143 0.0213
Loa Loa (eye worm) hypothetical protein 0.0197 0.0237 0.0604
Schistosoma mansoni hypothetical protein 0.025 0.0309 0.046
Entamoeba histolytica hypothetical protein 0.024 0.0296 0.5254
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Mycobacterium tuberculosis Probable esterase LipL 0.0201 0.0243 0.0615
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0099 0.0104 0.0154
Echinococcus granulosus mitogen activated protein kinase 3 0.0048 0.0034 0.0051
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0045 0.003 0.0043
Echinococcus granulosus mitogen activated protein kinase 0.0048 0.0034 0.0051
Echinococcus multilocularis Protein lozenge 0.0051 0.0037 0.0037
Schistosoma mansoni zinc finger protein 0.0088 0.0089 0.0132
Mycobacterium tuberculosis Probable transmembrane cytochrome C oxidase (subunit II) CtaC 0.0087 0.0087 0.0217
Echinococcus multilocularis protein dispatched 1 0.0214 0.026 0.026
Echinococcus multilocularis methyl CpG binding domain protein 2 0.007 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0172 0.0203 0.0516
Echinococcus multilocularis protein patched 0.0187 0.0224 0.0224
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0128 0.0143 0.0363
Echinococcus granulosus ecdysone induced protein 78C 0.0099 0.0104 0.0155
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0025 0.0003 0.0002
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.011 0.0119 0.0298
Echinococcus granulosus g protein coupled receptor 0.0026 0.0003 0.0005
Trypanosoma cruzi chloride channel protein, putative 0.0172 0.0203 0.0513
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0326 0.0413 0.1387
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0153 0.0177 0.0448
Trypanosoma brucei THT1 - hexose transporter, putative 0.0029 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.1829 0.2463 0.6301
Toxoplasma gondii heat shock protein HSP90 0.0115 0.0126 0.0317
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0128 0.0143 0.0213
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.2889 0.3909 0.5832
Onchocerca volvulus 0.0128 0.0143 0.0479
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Echinococcus granulosus Niemann Pick C1 protein 0.0437 0.0564 0.0842
Brugia malayi hypothetical protein 0.0088 0.0089 0.0226
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.011 0.0119 0.0298
Toxoplasma gondii CBS domain-containing protein 0.0172 0.0203 0.0513
Plasmodium falciparum thioredoxin reductase 0.0045 0.003 0.008
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0029 0.0008 0.0012
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0025 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0099 0.0104 0.0264
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0046 0.0032 0.0105
Plasmodium falciparum threonine--tRNA ligase 0.0025 0.0003 0.0007
Brugia malayi larval opioid receptor 0.0026 0.0003 0.0007
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.011 0.0119 0.0298
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0281 0.0351 0.5882
Toxoplasma gondii patched family protein 0.0026 0.0005 0.0006
Brugia malayi Cation transporter family protein 0.0128 0.0143 0.0363
Schistosoma mansoni histamine h1 receptor 0.0026 0.0003 0.0004
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0029 0.0009 0.0013
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0128 0.0143 0.0143
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0375 0.0481 0.1224
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0153 0.0177 0.0477
Loa Loa (eye worm) hypothetical protein 0.0309 0.039 0.0996
Mycobacterium ulcerans DNA polymerase IV 0.0033 0.0013 0.0027
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0012 0.0025
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Onchocerca volvulus 0.0026 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Echinococcus granulosus methyl CpG binding domain protein 2 0.007 0.0064 0.0096
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0172 0.0203 0.0301
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0037 0.0019 0.0019
Echinococcus multilocularis mothers against decapentaplegic 5 0.0061 0.0051 0.0051
Onchocerca volvulus Putative nachr subunit 0.0128 0.0143 0.0479
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0029 0.0009 0.0013
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0077 0.0074 0.0186
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0069 0.0063 0.0172
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.011 0.0119 0.0298
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0035 0.0016 0.0036
Plasmodium falciparum calcium-dependent protein kinase 1 0.0029 0.0009 0.0023
Schistosoma mansoni SET domain protein 0.0026 0.0004 0.0005
Loa Loa (eye worm) heterochromatin protein 1 0.0141 0.016 0.0408
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0099 0.0104 0.0104
Schistosoma mansoni hypothetical protein 0.024 0.0296 0.0441
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0294 0.037 0.0941
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0355 0.119
Loa Loa (eye worm) hypothetical protein 0.0099 0.0104 0.0264
Trypanosoma brucei DNA polymerase eta, putative 0.0033 0.0013 0.0028
Brugia malayi glycyl-tRNA synthetase 0.0025 0.0003 0.0005
Echinococcus granulosus lysosomal alpha glucosidase 0.0111 0.012 0.0179
Onchocerca volvulus 0.0026 0.0003 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.0375 0.0481 0.1224
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0326 0.0413 0.1052
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.046 0.0595 0.162
Schistosoma mansoni hypothetical protein 0.0094 0.0097 0.0144
Brugia malayi RE15519p 0.0026 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0097 0.0101 0.0151
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.1372 0.184 0.4704
Trypanosoma brucei hypothetical protein, conserved 0.0201 0.0243 0.0616
Echinococcus granulosus glycyl tRNA synthetase 0.0025 0.0003 0.0004
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Giardia lamblia NADH oxidase lateral transfer candidate 0.0045 0.003 0.0831
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Loa Loa (eye worm) AMP-binding enzyme family protein 0.011 0.0119 0.0302
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0084 0.0282
Loa Loa (eye worm) hypothetical protein 0.0088 0.0089 0.0226
Echinococcus granulosus para nitrobenzyl esterase 0.0309 0.039 0.0582
Onchocerca volvulus 0.0309 0.039 0.1311
Trypanosoma brucei GMP reductase 0.2889 0.3909 1
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Schistosoma mansoni nAChR subunit 0.0128 0.0143 0.0211
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0201 0.0243 0.0361
Brugia malayi Patched protein homolog 1 0.0026 0.0005 0.001
Schistosoma mansoni tar DNA-binding protein 0.0395 0.0507 0.0756
Schistosoma mansoni hypothetical protein 0.0047 0.0033 0.0048
Schistosoma mansoni acetylcholinesterase 0.0309 0.039 0.0581
Leishmania major inosine-5-monophosphate dehydrogenase 0.2889 0.3909 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0427 0.0551 0.1408
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0028 0.0007 0.0019
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0029 0.0008 0.0018
Echinococcus granulosus neuropeptide s receptor 0.0973 0.1295 0.1932
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0059 0.0049 0.0123
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0128 0.0143 0.0211
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.035 0.0446 0.0664
Trypanosoma brucei glucose transporter, putative 0.0029 0.0009 0.0016
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0099 0.0104 0.0155
Echinococcus granulosus hyperpolarization activated cyclic 0.0029 0.0008 0.0012
Plasmodium falciparum protein kinase 7 0.0267 0.0333 0.0905
Schistosoma mansoni hypothetical protein 0.025 0.0309 0.046
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0037 0.002 0.0044
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Schistosoma mansoni cellular tumor antigen P53 0.0158 0.0184 0.0274
Brugia malayi RNA, U transporter 1 0.0114 0.0124 0.0315
Onchocerca volvulus Glucosylceramidase homolog 0.0226 0.0277 0.0929
Onchocerca volvulus 0.0059 0.0049 0.0164
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0081 0.0078 0.0199
Echinococcus granulosus H:Cl exchange transporter 7 0.0172 0.0203 0.0302
Echinococcus granulosus Nuclear hormone receptor HR96 0.0047 0.0033 0.0049
Schistosoma mansoni cpg binding protein 0.0117 0.0128 0.0189
Brugia malayi GMP reductase 0.1201 0.1606 0.4108
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0057 0.0083
Loa Loa (eye worm) hypothetical protein 0.0028 0.0007 0.0015
Toxoplasma gondii LsmAD domain-containing protein 0.0088 0.0089 0.0223
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0061 0.0051 0.0051
Echinococcus granulosus GTP binding nuclear protein Ran 0.0029 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Schistosoma mansoni hypothetical protein 0.0026 0.0003 0.0004
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0026 0.0003 0.0004
Brugia malayi nuclear hormone receptor 0.0099 0.0104 0.0264
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1829 0.2463 0.3675
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0201 0.0243 0.0656
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0079 0.0076 0.0256
Schistosoma mansoni coup transcription factor 0.0099 0.0104 0.0154
Loa Loa (eye worm) hypothetical protein 0.0451 0.0583 0.1491
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0338 0.0429 0.1441
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0201 0.0242 0.0654
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0099 0.0104 0.0264
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0025 0.0003 0.0002
Trypanosoma brucei Heat shock protein 83, putative 0.0115 0.0126 0.0317
Schistosoma mansoni protein kinase 0.0029 0.0009 0.0012
Trypanosoma brucei glucose transporter, putative 0.0029 0.0009 0.0016
Leishmania major hypothetical protein, conserved 0.0028 0.0007 0.0013
Plasmodium vivax ataxin-2 like protein, putative 0.0088 0.0089 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0009 0.0012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0069 0.0063 0.0063
Mycobacterium ulcerans heat shock protein 90 0.0105 0.0112 0.028
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0338 0.0429 0.7608
Loa Loa (eye worm) hypothetical protein 0.0437 0.0564 0.1442
Loa Loa (eye worm) neuropeptide F receptor 0.0026 0.0003 0.0007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0265 0.033 0.0839
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 0.0835 0.1107 0.2827
Echinococcus granulosus tumor protein p63 0.108 0.1442 0.2151
Echinococcus multilocularis lysosomal alpha glucosidase 0.0111 0.012 0.012
Brugia malayi CHE-14 protein 0.0187 0.0224 0.0572
Loa Loa (eye worm) runx1 0.0051 0.0037 0.0094
Entamoeba histolytica acyl-CoA synthetase, putative 0.0375 0.0481 0.8519
Brugia malayi acetyl-Coenzyme A synthetase 2 0.011 0.0119 0.0302
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0099 0.0104 0.0264
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0128 0.0143 0.0143
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0338 0.0429 0.0429
Onchocerca volvulus 0.0059 0.0049 0.0164
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0045 0.003 0.0069
Schistosoma mansoni prolyl-tRNA synthetase 0.0066 0.0058 0.0085
Trypanosoma brucei THT1 - hexose transporter, putative 0.0029 0.0009 0.0016
Trypanosoma cruzi importin beta-1 subunit, putative 0.0032 0.0013 0.0027
Loa Loa (eye worm) IMP dehydrogenase 1 0.2889 0.3909 1
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0374 0.0479 0.0479
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.046 0.0595 0.0888
Echinococcus granulosus tachykinin peptides receptor 99D 0.0026 0.0003 0.0005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0121 0.0134 0.0336
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.2889 0.3909 1
Brugia malayi cytochrome P450 0.0025 0.0003 0.0007
Brugia malayi MAP kinase sur-1 0.0048 0.0034 0.0086
Mycobacterium tuberculosis Conserved protein 0.0201 0.0243 0.0615
Onchocerca volvulus 0.0303 0.0382 0.1283
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0187 0.0223 0.0569
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0048 0.0034 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0226 0.0277 0.0928
Brugia malayi Glycosyl hydrolases family 31 protein 0.0025 0.0002 0.0004
Trypanosoma cruzi trypanothione reductase, putative 0.0129 0.0145 0.0364
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0048 0.0034 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0076 0.0254
Onchocerca volvulus 0.0026 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0086 0.0086 0.0219
Echinococcus granulosus nuclear receptor nhr 48 0.0047 0.0033 0.0049
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0016 0.0053
Loa Loa (eye worm) hypothetical protein 0.0065 0.0058 0.0146
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.2718 0.3675 0.9401
Brugia malayi hypothetical protein 0.0059 0.0049 0.0123
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0099 0.0104 0.0264
Schistosoma mansoni tar DNA-binding protein 0.0395 0.0507 0.0756
Plasmodium falciparum calcium-dependent protein kinase 2 0.0029 0.0009 0.0023
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0069 0.0063 0.0168
Echinococcus granulosus lamin 0.0077 0.0074 0.011
Schistosoma mansoni integrin alpha-ps 0.0034 0.0015 0.0021
Plasmodium vivax glycine--tRNA ligase, putative 0.0025 0.0003 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.035 0.0446 0.0664
Brugia malayi chloride channel protein 7 0.0172 0.0203 0.0516
Loa Loa (eye worm) ACC-1 protein 0.0128 0.0143 0.0363
Onchocerca volvulus 0.0026 0.0003 0.0012
Brugia malayi G-protein coupled receptor 0.0026 0.0003 0.0007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0355 0.119
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0013 0.0031
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0057 0.0138
Mycobacterium ulcerans acyl-CoA synthetase 0.011 0.0119 0.0298
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0059 0.0049 0.0123
Entamoeba histolytica hypothetical protein 0.024 0.0296 0.5254
Brugia malayi SET domain containing protein 0.0026 0.0004 0.0009
Echinococcus granulosus heat shock protein 90 0.0115 0.0126 0.0188
Brugia malayi follicle stimulating hormone receptor 0.0187 0.0223 0.0569
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.004 0.0023 0.0034
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0148 0.017 0.017
Trypanosoma brucei glucose transporter, putative 0.0029 0.0009 0.0016
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.0355 0.6285
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0028 0.0007 0.0011
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0019 0.0043
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.028 0.035 0.035
Trypanosoma cruzi trypanothione reductase, putative 0.0045 0.003 0.007
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0003 0.0005
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0059 0.0049 0.0049
Echinococcus granulosus lysine specific demethylase 6a 0.0037 0.002 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0099 0.0104 0.0264
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0059 0.0049 0.0123
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0106 0.0113 0.2008
Echinococcus multilocularis mitogen activated protein kinase 0.0048 0.0034 0.0034
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0069 0.0063 0.0156
Echinococcus granulosus histone acetyltransferase KAT2B 0.0035 0.0016 0.0024
Echinococcus granulosus heat shock protein 0.0115 0.0126 0.0188
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0265 0.033 0.0839
Schistosoma mansoni cytochrome P450 0.0025 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Loa Loa (eye worm) hypothetical protein 0.0077 0.0074 0.0186
Echinococcus granulosus nAChR subunit 0.0128 0.0143 0.0213
Trichomonas vaginalis glucosylceramidase, putative 0.0226 0.0277 0.0928
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0026 0.0003 0.0004
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0094 0.0097 0.0145
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0229 0.0281 0.0417
Leishmania major CBS domain protein, conserved 0.0172 0.0203 0.0513
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0128 0.0143 0.0363
Echinococcus granulosus g protein coupled receptor 0.0026 0.0003 0.0005
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0099 0.0104 0.0264
Treponema pallidum Mg2+ transport protein (mgtE) 0.0172 0.0203 0.3375
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0172 0.0203 0.0203
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0057 0.0057
Echinococcus multilocularis carboxylesterase 5A 0.1829 0.2463 0.2463
Brugia malayi Intermediate filament tail domain containing protein 0.0077 0.0074 0.0186
Leishmania major hypothetical protein, conserved 0.0172 0.0203 0.0513
Onchocerca volvulus 0.0128 0.0143 0.0479
Trypanosoma brucei trypanothione reductase 0.0129 0.0145 0.0364
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.011 0.0119 0.0298
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0025 0.0003 0.0002
Plasmodium vivax acyl-CoA synthetase, putative 0.0281 0.0351 0.0951
Onchocerca volvulus 0.0201 0.0243 0.0816
Leishmania major GTP-binding protein, putative 0.0029 0.0009 0.0017
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0026 0.0003 0.0012
Schistosoma mansoni neuropeptide receptor 0.0026 0.0003 0.0004
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0012 0.0025
Echinococcus multilocularis neuropeptide receptor 0.0026 0.0003 0.0003
Toxoplasma gondii isocitrate dehydrogenase 0.0069 0.0063 0.0156
Loa Loa (eye worm) hypothetical protein 0.0041 0.0024 0.006
Trypanosoma brucei heat shock protein, putative 0.0115 0.0126 0.0317
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0025 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Schistosoma mansoni hypothetical protein 0.0026 0.0003 0.0004
Echinococcus multilocularis JmjC domain containing protein 4 0.0037 0.002 0.002
Brugia malayi hypothetical protein 0.0026 0.0003 0.0007
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0013 0.0031
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0158 0.0185 0.0466
Trypanosoma cruzi PAB1-binding protein , putative 0.0088 0.0089 0.0223
Loa Loa (eye worm) hypothetical protein 0.0116 0.0126 0.0321
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0053 0.004 0.006
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0007 0.0011
Schistosoma mansoni lipoxygenase 0.0059 0.0049 0.0072
Echinococcus multilocularis phd:f box containing protein 0.0037 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0057 0.0047 0.0118
Onchocerca volvulus 0.0128 0.0143 0.0479
Onchocerca volvulus 0.0099 0.0104 0.035
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) 0.0835 0.1107 0.2828
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0069 0.0063 0.0063
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0003 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0395 0.0507 0.0756
Trichomonas vaginalis glucosylceramidase, putative 0.0344 0.0438 0.147
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0048 0.0034 0.0049
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0025 0.0003 0.0003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0045 0.003 0.007
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0069 0.0062 0.0157
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0158 0.0185 0.0498
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Brugia malayi Cation transporter family protein 0.0128 0.0143 0.0363
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0019 0.0043
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0037 0.0019 0.0029
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0013 0.0028
Echinococcus granulosus mothers against decapentaplegic 5 0.0061 0.0051 0.0077
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0375 0.0481 0.1224
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0085 0.0084 0.0283
Trichomonas vaginalis antibiotic synthetase, putative 0.011 0.0119 0.0398
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0025 0.0003 0.0003
Schistosoma mansoni lozenge 0.0051 0.0037 0.0055
Echinococcus multilocularis neuropeptide FF receptor 2 0.0026 0.0003 0.0003
Echinococcus multilocularis lysosomal alpha glucosidase 0.0111 0.012 0.012
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0108 0.0116 0.0173
Schistosoma mansoni integrin alpha 0.0076 0.0072 0.0106
Plasmodium falciparum calcium-dependent protein kinase 3 0.0029 0.0009 0.0023
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0028 0.0007 0.0007
Schistosoma mansoni biogenic amine receptor 0.0026 0.0003 0.0004
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0009 0.0027
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0037 0.002 0.0044
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.011 0.0119 0.2106
Plasmodium falciparum calcium-dependent protein kinase 4 0.0029 0.0009 0.0023
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0051 0.0038 0.0057
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0108 0.0116 0.0315
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD 0.0835 0.1107 0.2827
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0035 0.0016 0.0053
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0128 0.0143 0.0143
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0026 0.0003 0.0003
Onchocerca volvulus 0.0062 0.0053 0.0178
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0029 0.0009 0.0019
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0048 0.0034 0.0082
Loa Loa (eye worm) hypothetical protein 0.0158 0.0184 0.0468
Brugia malayi G protein-coupled receptor 0.0026 0.0003 0.0007
Schistosoma mansoni growth hormone secretagogue receptor 0.0026 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0036 0.0017 0.0042
Schistosoma mansoni BC026374 protein (S09 family) 0.0309 0.039 0.0581
Schistosoma mansoni heat shock protein 0.0115 0.0126 0.0187
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0046 0.0032 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0019 0.0043
Leishmania major chloride channel protein, putative 0.0172 0.0203 0.0513
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0029 0.0008 0.0012
Schistosoma mansoni acetylcholine receptor subunit beta 0.0059 0.0049 0.0072
Onchocerca volvulus 0.0586 0.0768 0.258
Leishmania major cathepsin L-like protease 0.0037 0.0019 0.0043
Schistosoma mansoni Smad4 0.0027 0.0006 0.0007
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0172 0.0203 0.0516
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0081
Loa Loa (eye worm) GMP reductase 0.1201 0.1606 0.4108
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Schistosoma mansoni tar DNA-binding protein 0.0395 0.0507 0.0756
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0025 0.0002 0.0006
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.2889 0.3909 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0108 0.0116 0.0294
Echinococcus multilocularis dro:myosuppressin receptor 0.0026 0.0003 0.0003
Onchocerca volvulus 0.0026 0.0003 0.0012
Schistosoma mansoni neuropeptide receptor 0.0026 0.0003 0.0004
Treponema pallidum heat shock protein 90 0.0105 0.0112 0.1845
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0046 0.0032 0.0105
Loa Loa (eye worm) hypothetical protein 0.0069 0.0062 0.0157
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0047 0.0033 0.0081
Loa Loa (eye worm) hypothetical protein 0.0539 0.0704 0.18
Brugia malayi Cytochrome P450 family protein 0.0087 0.0088 0.0222
Loa Loa (eye worm) glutathione reductase 0.0129 0.0145 0.0368
Echinococcus granulosus orexin receptor type 2 0.0026 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0081
Schistosoma mansoni memapsin-2 (A01 family) 0.0146 0.0167 0.0248
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Loa Loa (eye worm) integrin beta-2 0.0155 0.018 0.0459
Giardia lamblia Kinase, CMGC MAPK 0.0048 0.0034 0.0962
Plasmodium vivax calcium-dependent protein kinase, putative 0.0029 0.0009 0.0019
Echinococcus multilocularis glycine receptor subunit beta 0.0128 0.0143 0.0143
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0309 0.039 0.0581
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.002
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0375 0.0481 0.1224
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0033 0.0013 0.0027
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0032 0.0013 0.0027
Onchocerca volvulus 0.0026 0.0005 0.0016
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0158 0.0185 0.0502
Wolbachia endosymbiont of Brugia malayi hemolysin 0.0172 0.0203 0.0512
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.011 0.0119 0.0298
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0047 0.0033 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0007 0.002
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0025 0.0003 0.0002
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.025 0.0309 0.0461
Onchocerca volvulus 0.0128 0.0143 0.0479
Schistosoma mansoni cpg binding protein 0.0103 0.0109 0.0162
Brugia malayi Tachykinin-like peptides receptor 99D 0.0026 0.0003 0.0007
Brugia malayi Dopamine receptor 0.0026 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0197 0.0237 0.0604
Brugia malayi ecdysteroid receptor 0.0099 0.0104 0.0264
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.011 0.0119 0.0298
Brugia malayi jmjC domain containing protein 0.0182 0.0216 0.0552
Echinococcus granulosus chromobox protein 1 0.0141 0.016 0.0239
Brugia malayi latrophilin 2 splice variant baaae 0.0539 0.0704 0.18
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.046 0.0595 0.1517
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0128 0.0143 0.0363
Trichomonas vaginalis CAMK family protein kinase 0.0029 0.0009 0.0027
Toxoplasma gondii Hsp90 domain-containing protein 0.036 0.046 0.1172
Brugia malayi Latrophilin receptor protein 2 0.025 0.0309 0.0789
Echinococcus granulosus Niemann Pick C1 protein 0.0624 0.082 0.1223
Brugia malayi Bromodomain containing protein 0.016 0.0186 0.0475
Schistosoma mansoni chloride channel protein 0.0172 0.0203 0.0301
Brugia malayi sulfakinin receptor protein 0.0026 0.0003 0.0007
Loa Loa (eye worm) nuclear factor I 0.0034 0.0014 0.0035
Brugia malayi AMP-binding enzyme family protein 0.0375 0.0481 0.1228
Trypanosoma cruzi heat shock protein 85, putative 0.0115 0.0126 0.0317
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Echinococcus multilocularis glycyl tRNA synthetase 0.0025 0.0003 0.0003
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0032 0.0013 0.0042
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0047 0.0033 0.0047
Echinococcus granulosus calcium dependent protein kinase 0.0027 0.0006 0.0008
Schistosoma mansoni gliotactin 0.0309 0.039 0.0581
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0013 0.0028
Brugia malayi RNA binding protein 0.0395 0.0507 0.1296
Echinococcus granulosus neuropeptide receptor 0.0026 0.0003 0.0005
Treponema pallidum prolyl-tRNA synthetase 0.0085 0.0085 0.1389
Echinococcus granulosus jumonji domain containing 1A 0.0037 0.002 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0099 0.0104 0.0264
Leishmania major glucose transporter, lmgt3 0.0029 0.0009 0.0016
Schistosoma mansoni thyroid hormone receptor 0.0474 0.0615 0.0916
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0201 0.0242 0.036
Loa Loa (eye worm) hypothetical protein 0.0086 0.0086 0.0219
Loa Loa (eye worm) PHD-finger family protein 0.0085 0.0084 0.0214
Onchocerca volvulus 0.0201 0.0243 0.0816
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0028 0.0007 0.0008
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.011 0.0119 0.0302
Echinococcus granulosus 7tm_1 domain containing protein 0.0026 0.0003 0.0005
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0108 0.0116 0.029
Schistosoma mansoni zinc finger protein 0.0063 0.0054 0.008
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.011 0.0119 0.0298
Plasmodium falciparum thioredoxin reductase 0.0129 0.0145 0.0393
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0029 0.0009 0.0243
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.046 0.0595 0.1518
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0789 0.1045 0.2671
Loa Loa (eye worm) hypothetical protein 0.0183 0.0219 0.0558
Trypanosoma cruzi hexose transporter 0.0029 0.0009 0.0016
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0048 0.0034 0.0082
Mycobacterium ulcerans acyl-CoA synthetase 0.011 0.0119 0.0298
Mycobacterium ulcerans beta-lactamase 0.0201 0.0243 0.0615
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0099 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0048 0.0034 0.0085
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0106 0.0113 0.2008
Loa Loa (eye worm) hypothetical protein 0.025 0.0309 0.0789
Trichomonas vaginalis glucosylceramidase, putative 0.0226 0.0277 0.0928
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Echinococcus multilocularis muscleblind protein 1 0.0197 0.0237 0.0237
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0301 0.0379 0.0965
Brugia malayi Cam kinase protein 1 0.0029 0.0009 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0344 0.0438 0.147
Loa Loa (eye worm) hypothetical protein 0.0201 0.0243 0.0619
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0201 0.0243 0.0615
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.0172 0.0203 0.0513
Brugia malayi AMP-binding enzyme family protein 0.0375 0.0481 0.1228
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Toxoplasma gondii hypothetical protein 0.0158 0.0185 0.0467
Loa Loa (eye worm) TAR-binding protein 0.0395 0.0507 0.1296
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0048 0.0034 0.0051
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0081
Loa Loa (eye worm) hypothetical protein 0.0403 0.0518 0.1323
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0053 0.004 0.0098
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0048 0.0034 0.0599
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Loa Loa (eye worm) hypothetical protein 0.0099 0.0104 0.0264
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.011 0.0119 0.0298
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0017 0.0056
Echinococcus granulosus endoplasmin 0.0105 0.0112 0.0167
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0099 0.0104 0.0264
Loa Loa (eye worm) hypothetical protein 0.0069 0.0062 0.0157
Mycobacterium tuberculosis Conserved protein 0.0172 0.0203 0.0512
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0025 0.0003 0.0003
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0294 0.037 0.0941
Schistosoma mansoni nuclear receptor nhr-48 0.0047 0.0033 0.0047
Schistosoma mansoni DNA polymerase eta 0.0033 0.0013 0.0018
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Brugia malayi MH1 domain containing protein 0.0034 0.0014 0.0035
Echinococcus granulosus ubiquitin specific protease 41 0.0028 0.0007 0.001
Loa Loa (eye worm) loechrig isoform VII 0.0172 0.0203 0.0516
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Echinococcus multilocularis voltage gated potassium channel 0.0041 0.0024 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0034 0.005
Schistosoma mansoni Smad4 0.0061 0.0051 0.0075
Brugia malayi F/Y-rich N-terminus family protein 0.0056 0.0045 0.0114
Brugia malayi hypothetical protein 0.0026 0.0003 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0019 0.0043
Echinococcus multilocularis fmrfamide receptor 0.0026 0.0003 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0375 0.0481 0.1228
Brugia malayi hypothetical protein 0.0026 0.0003 0.0007
Treponema pallidum NADH oxidase 0.0045 0.003 0.0456
Echinococcus granulosus cpg binding protein 0.0117 0.0128 0.0191
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Onchocerca volvulus 0.0026 0.0003 0.0012
Echinococcus granulosus acetylcholinesterase 0.1829 0.2463 0.3676
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0029 0.0009 0.0017
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.2889 0.3909 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Trichomonas vaginalis penicillin-binding protein, putative 0.0201 0.0243 0.0815
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Trichomonas vaginalis chromobox protein, putative 0.0141 0.016 0.0537
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0099 0.0104 0.0155
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Loa Loa (eye worm) G-protein coupled receptor 0.0026 0.0003 0.0007
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0029 0.0009 0.0009
Brugia malayi jmjC domain containing protein 0.0154 0.0178 0.0454
Leishmania major mitochondrial DNA polymerase beta 0.023 0.0283 0.0717
Plasmodium falciparum acetyl-CoA synthetase, putative 0.011 0.0119 0.0323
Brugia malayi Sugar transporter family protein 0.0094 0.0097 0.0247
Loa Loa (eye worm) hypothetical protein 0.0053 0.004 0.0101
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0108 0.0116 0.029
Echinococcus granulosus peptidase Clp S14 family 0.0301 0.0379 0.0566
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0128 0.0143 0.0143
Loa Loa (eye worm) transcription factor SMAD2 0.089 0.1183 0.3024
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0029 0.0008 0.0012
Echinococcus granulosus neuropeptide receptor A26 0.0973 0.1295 0.1932
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0003 0.0003
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0069 0.0063 0.0156
Brugia malayi hypothetical protein 0.0026 0.0003 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0003 0.0004
Loa Loa (eye worm) Smad1 0.0061 0.0051 0.0129
Brugia malayi RNA recognition motif domain containing protein 0.0395 0.0507 0.1296
Onchocerca volvulus 0.0026 0.0003 0.0012
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.0008 0.0025
Echinococcus granulosus thyroid hormone receptor alpha 0.0047 0.0033 0.0049
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0172 0.0203 0.5711
Brugia malayi Cation transporter family protein 0.0128 0.0143 0.0363
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0121 0.0134 0.0447
Brugia malayi Pre-SET motif family protein 0.1938 0.2612 0.6681
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0045 0.003 0.007
Brugia malayi protein C24B5.3 0.0026 0.0005 0.001
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0026 0.0003 0.0003
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0099 0.0103 0.0103
Echinococcus granulosus GPCR family 2 0.025 0.0309 0.0461
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0099 0.0104 0.0154
Brugia malayi Smad1 0.0061 0.0051 0.0129
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0099 0.0104 0.0264
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0003 0.0003
Schistosoma mansoni microtubule-associated protein tau 0.4937 0.6702 1
Brugia malayi Nuclear hormone receptor-like 1 0.0099 0.0104 0.0264
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0029 0.0009 0.002
Onchocerca volvulus 0.0124 0.0138 0.0465
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0025 0.0003 0.0002
Brugia malayi hypothetical protein 0.0026 0.0003 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0034 0.0114
Leishmania major cathepsin L-like protease 0.0037 0.0019 0.0043
Toxoplasma gondii cytochrome p450 superfamily protein 0.0025 0.0003 0.0003
Plasmodium vivax patched family protein, putative 0.0026 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0403 0.0518 0.1323
Onchocerca volvulus 0.0309 0.039 0.1311
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0048 0.0034 0.0034
Trypanosoma brucei glucose transporter, putative 0.0029 0.0009 0.0016
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0028 0.0007 0.0015
Trichomonas vaginalis DNA polymerase eta, putative 0.0033 0.0013 0.0042
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.004 0.0059
Plasmodium falciparum acyl-CoA synthetase 0.0281 0.0351 0.0955
Trichomonas vaginalis maltase-glucoamylase, putative 0.0025 0.0002 0.0006
Plasmodium falciparum heat shock protein 90, putative 0.0063 0.0055 0.0149
Brugia malayi Patched related family protein 4 0.0026 0.0005 0.001
Echinococcus granulosus neuropeptides capa receptor 0.0026 0.0003 0.0005
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0051 0.0038 0.0038
Schistosoma mansoni amine GPCR 0.0026 0.0003 0.0004
Trypanosoma cruzi heat shock protein 85, putative 0.0097 0.0101 0.0254
Mycobacterium leprae Probable cystathionine beta-synthase CBS (Serine sulfhydrase) (Beta-thionase) (Hemoprotein H-450) 0.0172 0.0203 0.0512
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.046 0.0595 0.1616
Mycobacterium ulcerans acyl-CoA synthetase 0.011 0.0119 0.0298
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0029 0.0008 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0099 0.0104 0.0264
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0009 0.0016
Echinococcus granulosus BC026374 protein S09 family 0.0309 0.039 0.0582
Mycobacterium ulcerans cystathionine beta-synthase 0.0172 0.0203 0.0512
Brugia malayi hypothetical protein 0.0047 0.0033 0.0081
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0029 0.0009 0.0013
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.0172 0.0203 0.0513
Brugia malayi neuropeptide F receptor 0.0026 0.0003 0.0007
Brugia malayi SET domain containing protein 0.0035 0.0017 0.0041
Onchocerca volvulus 0.0309 0.039 0.1311
Brugia malayi steroid hormone receptor 0.0099 0.0104 0.0264
Trichomonas vaginalis ap endonuclease, putative 0.0108 0.0116 0.0387
Schistosoma mansoni opsin-like receptor 0.0026 0.0003 0.0004
Mycobacterium tuberculosis Conserved protein 0.0201 0.0243 0.0615
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0375 0.0481 0.1224
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0069 0.0062 0.0157
Leishmania major pantothenate kinase subunit, putative 0.0037 0.0019 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0025 0.0003 0.0002
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.004 0.0023 0.0023
Echinococcus granulosus H:Cl exchange transporter 4 0.0172 0.0203 0.0302
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Echinococcus multilocularis neuropeptide s receptor 0.0973 0.1295 0.1295
Echinococcus multilocularis nuclear receptor nhr 48 0.0047 0.0033 0.0033
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative 0.0835 0.1107 0.2828
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0128 0.0143 0.0363
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0128 0.0143 0.0211
Onchocerca volvulus 0.0026 0.0003 0.0012
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0029 0.0009 0.0009
Echinococcus granulosus chromobox protein 1 0.0141 0.016 0.0239
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1938 0.2612 0.6681
Trichomonas vaginalis alpha-glucosidase, putative 0.0025 0.0002 0.0006
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0128 0.0143 0.0213
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0148 0.017 0.0254
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0201 0.0243 0.0615
Leishmania major cytochrome p450-like protein 0.0032 0.0012 0.0025
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0027 0.0006 0.0019
Mycobacterium ulcerans acyl-CoA synthetase 0.011 0.0119 0.0298
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0128 0.0143 0.0363
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0309 0.039 0.1309
Brugia malayi hypothetical protein 0.0026 0.0005 0.001
Plasmodium vivax hexose transporter 0.0094 0.0097 0.026
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0128 0.0143 0.0363
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0026 0.0003 0.0003
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0026 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0081
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0099 0.0104 0.0104
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0128 0.0143 0.0211
Brugia malayi CBS domain containing protein 0.0172 0.0203 0.0516
Echinococcus multilocularis para nitrobenzyl esterase 0.0309 0.039 0.039
Echinococcus granulosus glycine receptor subunit alpha 1 0.0128 0.0143 0.0213
Onchocerca volvulus 0.011 0.0119 0.04
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0045 0.003 0.0069
Trypanosoma brucei heat shock protein 90, putative 0.0115 0.0126 0.0317
Schistosoma mansoni nAChR subunit 0.0128 0.0143 0.0211
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0024 0.0024
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.011 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0201 0.0243 0.0619
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0025 0.0003 0.0002
Trichomonas vaginalis heat shock protein, putative 0.0105 0.0112 0.0374
Toxoplasma gondii heat shock protein 75, putative 0.0071 0.0065 0.0161
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0045 0.003 0.007
Brugia malayi Calcitonin receptor-like protein seb-1 0.0789 0.1045 0.2671
Echinococcus granulosus potassium voltage gated channel subfamily KQT 0.0086 0.0086 0.0129
Echinococcus multilocularis G-protein coupled receptor, putative 0.0026 0.0003 0.0003
Echinococcus multilocularis jumonji domain containing protein 0.0028 0.0007 0.0007
Brugia malayi jmjC domain containing protein 0.0037 0.002 0.0048
Schistosoma mansoni retinoic acid receptor RXR 0.0099 0.0104 0.0154
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0028 0.0007 0.0013
Schistosoma mansoni hypothetical protein 0.0085 0.0084 0.0125
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0015 0.0048
Schistosoma mansoni ran 0.0029 0.0009 0.0012
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0029 0.0009 0.0019
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0172 0.0203 0.0513
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0026 0.0003 0.0004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0042 0.0026 0.0039
Echinococcus granulosus G protein coupled receptor 139 0.0026 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0099 0.0104 0.0264
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0053 0.004 0.0098
Schistosoma mansoni smad 0.0061 0.0051 0.0075
Brugia malayi AMP-binding enzyme family protein 0.011 0.0119 0.0302
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0108 0.0116 0.031
Echinococcus granulosus cytochrome P450 2K1 0.0025 0.0003 0.0005
Echinococcus granulosus fmrfamide receptor 0.0026 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0047 0.0033 0.0081
Loa Loa (eye worm) carboxylesterase 0.1829 0.2463 0.6301
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0375 0.0481 0.1224
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0025 0.0003 0.0043
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0025 0.0003 0.0007
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.011 0.0119 0.0299
Onchocerca volvulus 0.0026 0.0003 0.0012
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.2718 0.3675 1
Plasmodium falciparum lipid/sterol:H+ symporter 0.0026 0.0005 0.0012
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0029 0.0008 0.0011
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0326 0.0413 0.1387
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.046 0.0595 0.1517
Schistosoma mansoni hypothetical protein 0.0026 0.0003 0.0004
Leishmania major acetyl-CoA synthetase, putative 0.011 0.0119 0.0299
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0057 0.0139
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Onchocerca volvulus 0.0309 0.039 0.1311
Brugia malayi isocitrate dehydrogenase 0.0069 0.0063 0.016
Echinococcus multilocularis glycine receptor subunit beta 0.0128 0.0143 0.0143
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0026 0.0003 0.0004
Echinococcus granulosus mixed lineage leukemia protein mll 0.0036 0.0017 0.0026
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.028 0.035 0.0891
Toxoplasma gondii patched family protein 0.0026 0.0005 0.0006
Trichomonas vaginalis esterase, putative 0.0201 0.0243 0.0815
Leishmania major heat shock protein 83-1 0.0115 0.0126 0.0317
Loa Loa (eye worm) jmjC domain-containing protein 0.0154 0.0178 0.0454
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0338 0.0429 0.0429
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0099 0.0104 0.0155
Trichomonas vaginalis ap endonuclease, putative 0.0108 0.0116 0.0387
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0835 0.1107 0.3009
Echinococcus granulosus serotonin receptor 0.0026 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0128 0.0143 0.0363
Loa Loa (eye worm) hypothetical protein 0.0053 0.004 0.0101
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.011 0.0119 0.0299
Loa Loa (eye worm) steroid hormone receptor 0.0099 0.0104 0.0264
Schistosoma mansoni alpha glucosidase 0.0025 0.0002 0.0002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0046 0.0032 0.0105
Schistosoma mansoni glucose transport protein 0.0094 0.0097 0.0144
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0069 0.0063 0.0095
Brugia malayi AMP-binding enzyme family protein 0.011 0.0119 0.0302
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.046 0.0595 1
Plasmodium falciparum endoplasmin, putative 0.0081 0.0079 0.0216
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0835 0.1107 0.2828
Echinococcus multilocularis heat shock protein 90 0.0115 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0069 0.0062 0.0157
Mycobacterium ulcerans hypothetical protein 0.0375 0.0481 0.1224
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0036 0.0017 0.0017
Mycobacterium leprae conserved hypothetical protein 0.0201 0.0243 0.0615
Plasmodium vivax heat shock protein 90, putative 0.0071 0.0065 0.0173
Trichomonas vaginalis glucosylceramidase, putative 0.0344 0.0438 0.147
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0045 0.003 0.003
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0026 0.0003 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0344 0.0438 0.147
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0003 0.0003
Mycobacterium tuberculosis Probable hydrolase 0.0201 0.0243 0.0615
Loa Loa (eye worm) MH2 domain-containing protein 0.089 0.1183 0.3024
Mycobacterium ulcerans hypothetical protein 0.0201 0.0243 0.0615
Brugia malayi beta-lactamase family protein 0.0201 0.0243 0.0619
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0026 0.0003 0.0005
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0086 0.0086 0.0086
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0109 0.0117 0.0294
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0172 0.0203 0.0302
Loa Loa (eye worm) hypothetical protein 0.0099 0.0104 0.0264
Echinococcus multilocularis g protein coupled receptor 0.0026 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0079 0.0076 0.0193
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0045 0.003 0.007
Schistosoma mansoni phd/f-box containing protein 0.0037 0.002 0.0028
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0309 0.039 0.039
Trypanosoma brucei glucose transporter, putative 0.0029 0.0009 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0003 0.0003
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0037 0.0019 0.0028
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0029 0.0009 0.0017
Loa Loa (eye worm) beta-lactamase 0.0201 0.0243 0.0619
Mycobacterium ulcerans hypothetical protein 0.0172 0.0203 0.0512
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Trichomonas vaginalis heat shock protein, putative 0.0097 0.0101 0.0339
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.025 0.0309 0.0461
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0025 0.0003 0.0002
Schistosoma mansoni protein kinase subunit gamma 0.0172 0.0203 0.0301
Entamoeba histolytica hypothetical protein 0.0032 0.0013 0.0225
Plasmodium falciparum cytochrome c oxidase subunit 2, putative 0.0087 0.0087 0.0237
Loa Loa (eye worm) latrophilin receptor protein 2 0.025 0.0309 0.0789
Onchocerca volvulus Neuropeptide F receptor homolog 0.0026 0.0003 0.0012
Schistosoma mansoni hypothetical protein 0.0374 0.0479 0.0714
Onchocerca volvulus 0.0026 0.0003 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0355 0.119
Trichomonas vaginalis D-aminoacylase, putative 0.0201 0.0243 0.0815
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0344 0.0438 0.1118
Onchocerca volvulus 0.0064 0.0056 0.0189
Loa Loa (eye worm) hypothetical protein 0.006 0.005 0.0125
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0099 0.0104 0.0154
Echinococcus multilocularis General substrate transporter 0.0081 0.0079 0.0079
Mycobacterium ulcerans acyl-CoA synthetase 0.011 0.0119 0.0298
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0309 0.039 0.0992
Plasmodium falciparum proline--tRNA ligase, putative 0.0066 0.0058 0.0158
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.011 0.0119 0.0298
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0094 0.0097 0.0145
Echinococcus multilocularis g protein coupled receptor 0.0026 0.0003 0.0003
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0525 0.0684 0.1746
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0309 0.039 0.0582
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.003 0.007
Onchocerca volvulus 0.0077 0.0074 0.0247
Mycobacterium ulcerans carboxylesterase, LipT 0.0309 0.039 0.0992
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0045 0.0149
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0267 0.0332 0.0848
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0105 0.0112 0.028
Onchocerca volvulus 0.0375 0.0481 0.1615
Brugia malayi Carboxylesterase family protein 0.1829 0.2463 0.6301
Plasmodium falciparum hexose transporter 0.0094 0.0097 0.0264
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.0097 0.0325
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0003 0.0004
Echinococcus granulosus survival motor neuron protein 1 0.1268 0.1698 0.2533
Toxoplasma gondii cytochrome C oxidase subunit IIb, putative 0.0087 0.0087 0.0217
Echinococcus granulosus cytochrome c oxidase subunit II 0.0287 0.0361 0.0538
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0327 0.0415 0.1055
Echinococcus multilocularis lamin 0.0077 0.0074 0.0074
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0084 0.0084 0.0125
Onchocerca volvulus 0.0026 0.0003 0.0012
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0025 0.0003 0.0002
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0099 0.0103 0.0153
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0032 0.0013 0.0027
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0267 0.0333 0.0497
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0003 0.0004
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0835 0.1107 0.283
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0046 0.0032 0.0105
Echinococcus granulosus TGF beta signal transducer SmadC 0.0061 0.0051 0.0077
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0019 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0099 0.0104 0.0264
Loa Loa (eye worm) AMP-binding enzyme family protein 0.011 0.0119 0.0302
Echinococcus granulosus thioredoxin glutathione reductase 0.0129 0.0145 0.0216
Leishmania major dihydroorotate dehydrogenase 0.0835 0.1107 0.2828
Brugia malayi orphan nuclear receptor NR2E1 0.0047 0.0033 0.0081
Brugia malayi ORL1-like opioid receptor 0.0026 0.0003 0.0007
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative 0.0835 0.1107 0.2828
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.011 0.0119 0.0298
Echinococcus granulosus intermediate filament protein 0.0077 0.0074 0.011
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0128 0.0143 0.0143
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0045 0.003 0.0069
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0033 0.0013 0.0032
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0108 0.0116 0.205
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0069 0.0063 0.0156
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0028 0.0007 0.001
Brugia malayi Nuclear hormone receptor E75 0.0047 0.0033 0.0081
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0047 0.0033 0.0109
Brugia malayi ancient conserved domain protein 2 0.0172 0.0203 0.0516
Brugia malayi beta-lactamase family protein 0.0201 0.0243 0.0619
Brugia malayi TAR-binding protein 0.0395 0.0507 0.1296
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0029 0.0009 0.0016
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0047 0.0033 0.0033
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0048 0.0034 0.0085
Loa Loa (eye worm) hypothetical protein 0.0036 0.0017 0.0042
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0172 0.0203 0.0302
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0025 0.0003 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.0003 0.0005
Echinococcus multilocularis musashi 0.0077 0.0074 0.0074
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0025 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0047 0.0033 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0034 0.0114
Loa Loa (eye worm) nuclear hormone receptor 0.0047 0.0033 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0099 0.0104 0.0264
Echinococcus multilocularis tumor protein p63 0.108 0.1442 0.1442
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0375 0.0481 0.1224
Echinococcus multilocularis endoplasmin 0.0105 0.0112 0.0112
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD 0.0835 0.1107 0.2827
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0003 0.0003
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0071 0.0065 0.0097
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0123
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.2889 0.3909 1
Onchocerca volvulus 0.0059 0.0049 0.0164
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0029 0.0008 0.0008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0355 0.119
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0003 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0003 0.0003
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0128 0.0143 0.0363
Leishmania major heat shock protein, putative 0.0071 0.0065 0.0161
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0009 0.0027
Trypanosoma brucei glucose transporter, putative 0.0029 0.0009 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0009 0.0027
Loa Loa (eye worm) endoplasmin 0.0115 0.0126 0.032
Brugia malayi Patched family protein 0.0026 0.0005 0.001
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0059 0.0049 0.0073
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0053 0.004 0.0101
Loa Loa (eye worm) carboxylesterase 0.0309 0.039 0.0996
Trichomonas vaginalis alpha-glucosidase, putative 0.0025 0.0002 0.0006
Echinococcus multilocularis dnaJ subfamily B 0.0928 0.1235 0.1235
Schistosoma mansoni survival motor neuron protein 0.0259 0.0321 0.0478
Echinococcus granulosus glycine receptor subunit beta 0.0128 0.0143 0.0213
Loa Loa (eye worm) ACC-1 protein 0.0128 0.0143 0.0363
Onchocerca volvulus 0.0047 0.0033 0.0109
Brugia malayi hypothetical protein 0.0057 0.0047 0.0117
Mycobacterium tuberculosis Probable oxidoreductase 0.0327 0.0415 0.1055
Echinococcus multilocularis FTZ F1 alpha 0.0099 0.0104 0.0104
Onchocerca volvulus 0.0201 0.0243 0.0816
Plasmodium vivax heat shock protein, putative 0.036 0.046 0.1248
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0025 0.0002 0.0037
Loa Loa (eye worm) hypothetical protein 0.0026 0.0005 0.001
Onchocerca volvulus 0.0047 0.0033 0.0109
Loa Loa (eye worm) hypothetical protein 0.0128 0.0143 0.0363
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.002 0.0048
Echinococcus granulosus allatostatin A receptor 0.0026 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.051 0.0664 0.1696
Onchocerca volvulus 0.0026 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Echinococcus multilocularis chromobox protein 1 0.0141 0.016 0.016
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Leishmania major DNA polymerase kappa, putative 0.0033 0.0013 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.0375 0.0481 0.1224
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0031
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0128 0.0143 0.0363
Loa Loa (eye worm) hypothetical protein 0.0026 0.0003 0.0007
Trypanosoma cruzi heat shock protein 90, putative 0.0097 0.0101 0.0254
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0037 0.0019 0.0043
Loa Loa (eye worm) hypothetical protein 0.0309 0.039 0.0996
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0158 0.0185 0.307
Schistosoma mansoni voltage-gated potassium channel 0.0145 0.0166 0.0246
Schistosoma mansoni opsin-like receptor 0.0026 0.0003 0.0004
Brugia malayi Met-10+ like-protein 0.0056 0.0045 0.0112
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0355 0.119
Schistosoma mansoni ran 0.0029 0.0009 0.0012
Echinococcus granulosus expressed conserved protein 0.041 0.0528 0.0788

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 74 nM Binding affinity to PAR1 in human platelet membrane ChEMBL. 16824760
IC50 (binding) = 74 nM Binding affinity to PAR1 in human platelet membrane ChEMBL. 16824760

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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