Detailed information for compound 413778

Basic information

Technical information
  • TDR Targets ID: 413778
  • Name: (2S)-2-[(3S)-3-[(6-chloronaphthalen-2-yl)sulf onylamino]-2-oxopyrrolidin-1-yl]-N-propan-2-y lpropanamide
  • MW: 437.94 | Formula: C20H24ClN3O4S
  • H donors: 2 H acceptors: 4 LogP: 3.01 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(NC(=O)[C@@H](N1CC[C@@H](C1=O)NS(=O)(=O)c1ccc2c(c1)ccc(c2)Cl)C)C
  • InChi: 1S/C20H24ClN3O4S/c1-12(2)22-19(25)13(3)24-9-8-18(20(24)26)23-29(27,28)17-7-5-14-10-16(21)6-4-15(14)11-17/h4-7,10-13,18,23H,8-9H2,1-3H3,(H,22,25)/t13-,18-/m0/s1
  • InChiKey: NMPGSBDMLORZBL-UGSOOPFHSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-[(3S)-3-[(6-chloro-2-naphthyl)sulfonylamino]-2-oxo-pyrrolidin-1-yl]-N-isopropyl-propanamide
  • (2S)-2-[(3S)-3-[(6-chloro-2-naphthyl)sulfonylamino]-2-oxo-1-pyrrolidinyl]-N-isopropylpropanamide
  • (2S)-2-[(3S)-3-[(6-chloronaphthalen-2-yl)sulfonylamino]-2-oxo-pyrrolidin-1-yl]-N-propan-2-yl-propanamide
  • (2S)-2-[(3S)-3-[(6-chloro-2-naphthyl)sulfonylamino]-2-keto-pyrrolidino]-N-isopropyl-propionamide
  • (2S)-2-[(3S)-3-[(6-chloro-2-naphthyl)sulfonylamino]-2-keto-pyrrolidin-1-yl]-N-isopropyl-propionamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor X Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis neuropeptides capa receptor 0.0257 0.0371 0.0366
Echinococcus granulosus twitchin 0.0312 0.0509 0.0505
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0542 0.1082 0.1066
Echinococcus granulosus serine:threonine protein kinase N2 0.0854 0.186 0.1856
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0292 0.0459 0.142
Schistosoma mansoni netrin receptor unc5 0.0126 0.0044 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.0597 0.0592
Entamoeba histolytica protein kinase , putative 0.0425 0.079 0.2864
Onchocerca volvulus 0.0257 0.0371 0.1311
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0292 0.0459 0.1605
Toxoplasma gondii casein kinase I 0.0318 0.0523 0.1845
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0257 0.0371 0.0366
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0257 0.0371 0.0366
Giardia lamblia Kinase, NEK 0.0398 0.0722 0.3241
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0587 0.1193 0.1189
Trypanosoma brucei cdc2-related kinase 1 0.0347 0.0597 0.1875
Plasmodium vivax cysteine repeat modular protein 1, putative 0.036 0.0628 0.2235
Brugia malayi Protein kinase domain containing protein 0.0565 0.114 0.1124
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0586 0.1191 0.1186
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0112 0.0009 0.0004
Plasmodium vivax vivapain-3 0.066 0.1377 0.5033
Echinococcus multilocularis N chimaerin 0.0223 0.0286 0.0281
Entamoeba histolytica protein kinase, putative 0.012 0.0029 0.0031
Entamoeba histolytica PH domain containing protein kinase, putative 0.0314 0.0514 0.1836
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0176 0.0169 0.0164
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.036 0.0628 0.0623
Trichomonas vaginalis AGC family protein kinase 0.0246 0.0345 0.127
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0122 0.0034 0.0029
Toxoplasma gondii histone kinase SNF1, putative 0.0262 0.0383 0.1323
Onchocerca volvulus Serine\/threonine kinase homolog 0.0352 0.0609 0.2196
Echinococcus multilocularis Diacylglycerol kinase theta 0.0122 0.0034 0.0029
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0563 0.1133 0.1129
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0587 0.1193 0.3846
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2333 0.5548 0.5546
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Brugia malayi Protein kinase c protein 2 0.0338 0.0574 0.0557
Echinococcus granulosus cathepsin l1 0.1194 0.2707 0.2704
Mycobacterium ulcerans glutaminase 0.0274 0.0413 0.594
Echinococcus multilocularis mitogen activated protein kinase 14 0.0587 0.1193 0.1189
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0281 0.0432 0.1504
Echinococcus granulosus calcium dependent protein kinase 0.0219 0.0278 0.0273
Trichomonas vaginalis STE family protein kinase 0.0241 0.0332 0.1222
Echinococcus multilocularis myosin iiia 0.0248 0.0349 0.0344
Echinococcus multilocularis dro:myosuppressin receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0281 0.0432 0.0427
Schistosoma mansoni tyrosine kinase 0.0889 0.1947 0.1943
Brugia malayi Immunoglobulin I-set domain containing protein 0.0183 0.0188 0.017
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Brugia malayi Papain family cysteine protease containing protein 0.0281 0.0432 0.0415
Echinococcus granulosus geminin 0.017 0.0154 0.0149
Plasmodium falciparum serine repeat antigen 3 0.0281 0.0432 0.1504
Echinococcus multilocularis sex peptide receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis cyclin dependent kinase 1 0.0347 0.0597 0.0592
Echinococcus granulosus neuropeptides capa receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0281 0.0432 0.1592
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trypanosoma brucei protein kinase, putative 0.0204 0.0239 0.0693
Echinococcus multilocularis cysteine protease 0.1194 0.2707 0.2704
Trypanosoma cruzi casein kinase, putative 0.0318 0.0523 0.0895
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0453 0.086 0.0856
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0317 0.0521 0.1837
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0342 0.126
Giardia lamblia Cathepsin B precursor 0.0281 0.0432 0.1722
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0239 0.0326 0.0321
Onchocerca volvulus 0.0257 0.0371 0.1311
Schistosoma mansoni protein kinase 0.0447 0.0846 0.0841
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0281 0.0432 0.1592
Echinococcus granulosus g protein coupled receptor 0.0257 0.0371 0.0366
Echinococcus granulosus ephrin type A receptor 4 A 0.0292 0.046 0.0455
Loa Loa (eye worm) hypothetical protein 0.025 0.0353 0.0349
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Echinococcus granulosus mitogen activated protein kinase 11 0.0587 0.1193 0.1189
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Loa Loa (eye worm) hypothetical protein 0.0525 0.1041 0.1036
Echinococcus multilocularis cyclin dependent kinase 9 0.0149 0.0102 0.0097
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0542 0.1082 0.1078
Brugia malayi Cathepsin L-like precursor 0.1194 0.2707 0.2694
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Brugia malayi Protein kinase domain containing protein 0.1307 0.2988 0.2976
Mycobacterium leprae Conserved hypothetical protein 0.114 0.2573 1
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0168 0.015 0.0145
Brugia malayi Protein kinase domain containing protein 0.0563 0.1133 0.1117
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Echinococcus multilocularis raf serine:threonine protein kinase 0.0228 0.0299 0.0294
Brugia malayi bone morphogenetic protein type 1 receptor 0.0176 0.0169 0.0151
Schistosoma mansoni kinase 0.0141 0.0083 0.0078
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0656 0.1366 0.1362
Schistosoma mansoni tyrosine kinase 0.0282 0.0434 0.0429
Schistosoma mansoni serine/threonine protein kinase 0.0449 0.0849 0.0845
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0239 0.0326 0.0321
Loa Loa (eye worm) hypothetical protein 0.0138 0.0074 0.0069
Brugia malayi fibroinase precursor 0.0281 0.0432 0.0415
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0131 0.0126
Giardia lamblia Kinase, CMGC CLK 0.0449 0.0849 0.3905
Brugia malayi hypothetical protein 0.0201 0.0233 0.0215
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0149 0.0103 0.0276
Trichomonas vaginalis CAMK family protein kinase 0.0788 0.1695 0.626
Echinococcus granulosus tm gpcr rhodopsin 0.0257 0.0371 0.0366
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0318 0.0523 0.0895
Echinococcus multilocularis g-protein coupled receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis rac serine:threonine kinase 0.0479 0.0926 0.0921
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0317 0.0521 0.1625
Brugia malayi intracellular kinase 0.0376 0.0668 0.0651
Loa Loa (eye worm) hypothetical protein 0.0559 0.1125 0.1121
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Brugia malayi Protein kinase domain 0.0252 0.0359 0.0341
Loa Loa (eye worm) glutaminase 0.0274 0.0413 0.0408
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0487 0.1796
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0347 0.0597 0.2119
Brugia malayi Cathepsin L-like precursor 0.1194 0.2707 0.2694
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.0523 0.0518
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Trichomonas vaginalis CAMK family protein kinase 0.0788 0.1695 0.626
Loa Loa (eye worm) TK protein kinase 0.0378 0.0674 0.0669
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0457 0.0871 0.3144
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0257 0.0371 0.0366
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0477 0.0919 0.0915
Loa Loa (eye worm) hypothetical protein 0.0292 0.0459 0.0454
Echinococcus multilocularis neuropeptide s receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0245 0.0342 0.0568
Loa Loa (eye worm) hypothetical protein 0.0379 0.0676 0.0671
Brugia malayi MAP kinase sur-1 0.0245 0.0342 0.0325
Plasmodium falciparum serine/threonine protein kinase 0.0243 0.0338 0.1153
Entamoeba histolytica cell division protein kinase 2, putative 0.0347 0.0597 0.2144
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0252 0.0359 0.0354
Brugia malayi Furin-like cysteine rich region family protein 0.1205 0.2734 0.2721
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0317 0.0521 0.1837
Plasmodium vivax glycogen synthase kinase 3, putative 0.0376 0.0668 0.2387
Leishmania major protein kinase, putative 0.0248 0.0349 0.1057
Trichomonas vaginalis AGC family protein kinase 0.012 0.0029 0.0103
Loa Loa (eye worm) hypothetical protein 0.0317 0.0521 0.0516
Trypanosoma brucei casein kinase I, isoform 2 0.0318 0.0523 0.1632
Echinococcus granulosus cyclin dependent kinase 19 0.0224 0.029 0.0285
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0281 0.0432 0.1504
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0223 0.0286 0.0281
Schistosoma mansoni serine/threonine protein kinase 0.0948 0.2093 0.2089
Echinococcus granulosus somatostatin receptor 0.0257 0.0371 0.0366
Echinococcus granulosus dual specificity mitogen activated protein 0.0241 0.0332 0.0327
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0317 0.0521 0.1837
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.0459 0.0454
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0245 0.0342 0.0568
Trichomonas vaginalis STE family protein kinase 0.0241 0.0332 0.1222
Loa Loa (eye worm) TK/FER protein kinase 0.0796 0.1716 0.1712
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0083 0.0078
Loa Loa (eye worm) TYRA-2 protein 0.0257 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0188 0.0183
Giardia lamblia Hypothetical protein 0.0281 0.0432 0.1722
Onchocerca volvulus 0.0559 0.1125 0.4116
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0477 0.0919 0.0915
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0167 0.0147 0.0142
Echinococcus multilocularis Immunoglobulin 0.0165 0.0142 0.0138
Onchocerca volvulus Netrin receptor homolog 0.0134 0.0064 0.0172
Entamoeba histolytica protein kinase, putative 0.0208 0.0249 0.0849
Giardia lamblia Cathepsin B precursor 0.0281 0.0432 0.1722
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Trypanosoma cruzi NIMA-related kinase, putative 0.0149 0.0103 0.0134
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0352 0.0609 0.0604
Brugia malayi Doublecortin family protein 0.044 0.0829 0.0812
Brugia malayi Protein kinase domain containing protein 0.0224 0.029 0.0273
Trypanosoma cruzi casein kinase, putative 0.0318 0.0523 0.0895
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0955 0.2112 0.3773
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0469 0.0901 0.3256
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0721 0.1529 0.1525
Loa Loa (eye worm) hypothetical protein 0.0256 0.0369 0.0365
Leishmania major cathepsin L-like protease 0.1334 0.3057 1
Trichomonas vaginalis AGC family protein kinase 0.0425 0.079 0.2915
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Trichomonas vaginalis CAMK family protein kinase 0.0788 0.1695 0.626
Onchocerca volvulus 0.0325 0.0541 0.1946
Brugia malayi cathepsin Z-like cysteine proteinase 0.0485 0.0939 0.0923
Brugia malayi phosphoinositide-dependent protein kinase I 0.0239 0.0326 0.0308
Entamoeba histolytica PH domain containing protein kinase, putative 0.012 0.0029 0.0031
Loa Loa (eye worm) SRC-1 0.0453 0.086 0.0856
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0245 0.0342 0.0337
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0257 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0477 0.0919 0.0915
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0252 0.0359 0.0354
Brugia malayi putative neuropeptide receptor 0.0257 0.0371 0.0353
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0257 0.0371 0.0353
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0788 0.1695 0.1691
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1148 0.2594 0.259
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Entamoeba histolytica cysteine protease, putative 0.0281 0.0432 0.1531
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Trichomonas vaginalis CAMK family protein kinase 0.0317 0.0521 0.1921
Schistosoma mansoni vesicular amine transporter 0.0165 0.0142 0.0138
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Schistosoma mansoni tyrosine kinase 0.0282 0.0434 0.0429
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trypanosoma cruzi Protein kinase B 0.0479 0.0926 0.1625
Loa Loa (eye worm) hypothetical protein 0.1342 0.3077 0.3074
Echinococcus granulosus cathepsin b 0.2333 0.5548 0.5546
Loa Loa (eye worm) hypothetical protein 0.0325 0.0541 0.0537
Echinococcus multilocularis Rac GTPase activating protein 1 0.0122 0.0034 0.0029
Entamoeba histolytica protein kinase, putative 0.0836 0.1816 0.6683
Onchocerca volvulus 0.1194 0.2707 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Giardia lamblia Cathepsin B precursor 0.0916 0.2014 1
Leishmania major cathepsin L-like protease 0.1194 0.2707 0.8846
Schistosoma mansoni hypothetical protein 0.0257 0.0371 0.0366
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.1286 0.2937 0.2933
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0269 0.0402 0.1394
Entamoeba histolytica cysteine protease, putative 0.1194 0.2707 1
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Onchocerca volvulus 0.085 0.185 0.6812
Loa Loa (eye worm) hypothetical protein 0.0165 0.0142 0.0138
Loa Loa (eye worm) hypothetical protein 0.0675 0.1413 0.1409
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0281 0.0432 0.1504
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Onchocerca volvulus 0.0153 0.0113 0.0352
Echinococcus multilocularis g protein coupled receptor 0.0257 0.0371 0.0366
Brugia malayi Variant SH3 domain containing protein 0.0127 0.0047 0.0029
Echinococcus granulosus tyrosine protein kinase Lyn 0.055 0.1103 0.1099
Schistosoma mansoni protein kinase 0.0252 0.0359 0.0354
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2333 0.5548 1
Echinococcus granulosus g protein coupled receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis casein kinase I gamma 0.0506 0.0992 0.0987
Brugia malayi Protein kinase domain containing protein 0.0449 0.0849 0.0833
Leishmania major cysteine peptidase A (CPA) 0.1194 0.2707 0.8846
Leishmania major protein kinase, putative 0.0449 0.0849 0.2709
Echinococcus multilocularis somatostatin receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0257 0.0371 0.0366
Trypanosoma cruzi casein kinase II, putative 0.0293 0.0461 0.0783
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus granulosus protein kinase c iota type 0.0839 0.1824 0.182
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0257 0.0371 0.0366
Leishmania major protein kinase A catalytic subunit isoform 2 0.0292 0.0459 0.142
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0487 0.1796
Loa Loa (eye worm) hypothetical protein 0.0166 0.0144 0.0139
Schistosoma mansoni serine/threonine protein kinase 0.096 0.2123 0.212
Echinococcus granulosus allatostatin A receptor 0.0257 0.0371 0.0366
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1148 0.2594 0.259
Echinococcus granulosus acetylcholinesterase 0.0138 0.0074 0.0069
Echinococcus granulosus titin 0.0183 0.0188 0.0183
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0449 0.0849 0.2709
Echinococcus granulosus raf serine:threonine protein kinase 0.0228 0.0299 0.0294
Echinococcus multilocularis neuropeptide FF receptor 2 0.0257 0.0371 0.0366
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0357 0.0622 0.1074
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0257 0.0371 0.0366
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Plasmodium vivax unspecified product 0.0379 0.0676 0.2416
Onchocerca volvulus 0.0257 0.0371 0.1311
Echinococcus multilocularis 0.0338 0.0573 0.0568
Echinococcus granulosus protein kinase shaggy 0.0376 0.0668 0.0664
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Brugia malayi Cathepsin L-like precursor 0.1194 0.2707 0.2694
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0796 0.1716 0.1712
Plasmodium vivax vivapain-1 0.066 0.1377 0.5033
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0257 0.0371 0.0366
Trichomonas vaginalis CMGC family protein kinase 0.0376 0.0668 0.2465
Entamoeba histolytica p21-activated kinase 0.0274 0.0414 0.1463
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0156 0.0119 0.0114
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0156 0.0119 0.0114
Entamoeba histolytica cysteine proteinase, putative 0.1194 0.2707 1
Giardia lamblia Kinase, AGC AKT 0.0342 0.0584 0.2518
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0127 0.0048 0.0043
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0157 0.0122 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0131 0.0126
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0149 0.0103 0.0244
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Echinococcus granulosus dual specificity protein kinase clk2 0.0449 0.0849 0.0845
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Schistosoma mansoni cathepsin S (C01 family) 0.0281 0.0432 0.0427
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Giardia lamblia Cathepsin L precursor 0.0281 0.0432 0.1722
Giardia lamblia Cathepsin L-like protease 0.0281 0.0432 0.1722
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0479 0.0926 0.1625
Schistosoma mansoni serine/threonine-protein kinase 0.0479 0.0926 0.0921
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0292 0.0459 0.1605
Echinococcus multilocularis cyclin dependent kinase 19 0.0224 0.029 0.0285
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Onchocerca volvulus 0.0207 0.0248 0.0853
Brugia malayi Serine/threonine-protein kinase SULU 0.0648 0.1347 0.1331
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0423 0.0784 0.078
Trichomonas vaginalis AGC family protein kinase 0.0425 0.079 0.2915
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0257 0.0371 0.0366
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0325 0.0541 0.0537
Echinococcus granulosus cathepsin l cysteine peptidase 0.1194 0.2707 0.2704
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0916 0.2014 0.6557
Entamoeba histolytica cysteine protease, putative 0.0281 0.0432 0.1531
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Giardia lamblia Aurora kinase 0.0425 0.079 0.3596
Trichomonas vaginalis CMGC family protein kinase 0.0376 0.0668 0.2465
Loa Loa (eye worm) hypothetical protein 0.0375 0.0665 0.0661
Plasmodium vivax unspecified product 0.066 0.1377 0.5033
Schistosoma mansoni biogenic amine (5HT) receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0516 0.1018 0.3758
Loa Loa (eye worm) hypothetical protein 0.0164 0.014 0.0135
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0873 0.1907 0.1903
Loa Loa (eye worm) AGC/PKA protein kinase 0.0292 0.0459 0.0454
Echinococcus multilocularis serine:threonine protein kinase N2 0.0854 0.186 0.1856
Echinococcus granulosus CDC7 cell division cycle 7 0.0153 0.0113 0.0108
Loa Loa (eye worm) G-protein coupled receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) STE/STE11/MEKK2 protein kinase 0.0115 0.0018 0.0013
Plasmodium falciparum cysteine proteinase falcipain 3 0.1194 0.2707 1
Echinococcus multilocularis neuropeptide Y receptor 0.0257 0.0371 0.0366
Plasmodium falciparum serine/threonine protein kinase, putative 0.0425 0.079 0.2842
Trypanosoma brucei aurora B kinase 0.0425 0.079 0.2514
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1148 0.2594 0.259
Loa Loa (eye worm) hypothetical protein 0.0165 0.0142 0.0138
Schistosoma mansoni serine/threonine protein kinase 0.0272 0.0409 0.0404
Schistosoma mansoni serine/threonine protein kinase 0.0685 0.1439 0.1435
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0281 0.0432 0.1722
Echinococcus granulosus fmrfamide receptor 0.0257 0.0371 0.0366
Brugia malayi Fes/CIP4 homology domain containing protein 0.0291 0.0457 0.044
Brugia malayi Temporarily assigned gene name protein 59 0.0325 0.0541 0.0524
Brugia malayi Protein kinase domain containing protein 0.0385 0.0692 0.0675
Plasmodium vivax serine-repeat antigen (SERA) 0.0281 0.0432 0.1504
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0383 0.0379
Loa Loa (eye worm) hypothetical protein 0.0201 0.0233 0.0228
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0376 0.0668 0.2111
Onchocerca volvulus 0.0908 0.1996 0.7353
Schistosoma mansoni tyrosine kinase 0.08 0.1725 0.1721
Plasmodium vivax serine/threonine kinase-1, putative 0.0449 0.0849 0.3063
Echinococcus granulosus STE20 serine:threonine protein kinase 0.144 0.3321 0.3317
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0176 0.0169 0.0164
Entamoeba histolytica serine/threonine protein kinase, putative 0.0788 0.1695 0.6233
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Trichomonas vaginalis STE family protein kinase 0.0241 0.0332 0.1222
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Schistosoma mansoni myosin xvIII 0.0257 0.0371 0.0366
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0347 0.0597 0.1875
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Loa Loa (eye worm) TK protein kinase 0.0572 0.1156 0.1152
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0675 0.1413 0.1409
Loa Loa (eye worm) hypothetical protein 0.088 0.1926 0.1922
Giardia lamblia Cathepsin L-like protease 0.0281 0.0432 0.1722
Echinococcus granulosus c src tyrosine kinase 0.0282 0.0434 0.0429
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0281 0.0432 0.1592
Schistosoma mansoni alpha-1 adrenergic receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0257 0.0371 0.0366
Plasmodium falciparum serine repeat antigen 7 0.0281 0.0432 0.1504
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Brugia malayi Protein kinase domain containing protein 0.0654 0.1361 0.1345
Echinococcus granulosus cathepsin L 0.0281 0.0432 0.0427
Echinococcus granulosus titin 0.0183 0.0188 0.0183
Schistosoma mansoni tyrosine kinase 0.0453 0.086 0.0856
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0248 0.0349 0.058
Schistosoma mansoni neuropeptide receptor 0.0257 0.0371 0.0366
Schistosoma mansoni Replicative DNA helicase 0.0387 0.0695 0.069
Schistosoma mansoni tyrosine kinase 0.1205 0.2734 0.2731
Trichomonas vaginalis STE family protein kinase 0.0252 0.0359 0.1321
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Brugia malayi glutaminase DH11.1 0.0274 0.0413 0.0395
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0281 0.0432 0.1504
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Loa Loa (eye worm) hypothetical protein 0.0279 0.0427 0.0422
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Schistosoma mansoni kinase 0.0842 0.1829 0.1825
Schistosoma mansoni tyrosine kinase 0.0694 0.1461 0.1456
Trypanosoma cruzi cdc2-related kinase 3 0.0347 0.0597 0.1029
Echinococcus multilocularis c src tyrosine kinase 0.0282 0.0434 0.0429
Echinococcus granulosus mitogen activated protein kinase 0.0245 0.0342 0.0337
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0281 0.0432 0.1592
Entamoeba histolytica cysteine protease, putative 0.0281 0.0432 0.1531
Loa Loa (eye worm) hypothetical protein 0.0138 0.0074 0.0069
Echinococcus granulosus epidermal growth factor receptor 0.08 0.1725 0.1721
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Brugia malayi cathepsin L-like cysteine proteinase 0.0281 0.0432 0.0415
Echinococcus multilocularis protein kinase c epsilon type 0.0602 0.1232 0.1227
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0325 0.0541 0.1692
Brugia malayi Cathepsin L-like cysteine proteinase 0.0815 0.1762 0.1747
Brugia malayi G-protein coupled receptor 0.0257 0.0371 0.0353
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Plasmodium falciparum calcium-dependent protein kinase 3 0.0317 0.0521 0.1837
Echinococcus granulosus dual specificity 0.0303 0.0487 0.0482
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Plasmodium falciparum serine repeat antigen 2 0.0281 0.0432 0.1504
Echinococcus multilocularis insulin receptor 0.0889 0.1947 0.1943
Echinococcus granulosus cathepsin L 0.066 0.1377 0.1373
Giardia lamblia Hypothetical protein 0.0281 0.0432 0.1722
Entamoeba histolytica protein kinase, putative 0.0477 0.0919 0.3344
Schistosoma mansoni glutaminase 0.0274 0.0413 0.0408
Echinococcus granulosus tachykinin peptides receptor 99D 0.0257 0.0371 0.0366
Giardia lamblia Kinase, PLK 0.0788 0.1695 0.8331
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0278 0.0423 0.0418
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Echinococcus granulosus protein kinase 0.0447 0.0846 0.0841
Entamoeba histolytica hypothetical protein 0.0281 0.0432 0.1531
Onchocerca volvulus 0.0257 0.0371 0.1311
Brugia malayi Tyrosine-protein kinase abl-1 0.036 0.0628 0.0611
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0243 0.0338 0.1153
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Entamoeba histolytica cysteine proteinase, putative 0.066 0.1377 0.5049
Schistosoma mansoni amine GPCR 0.0257 0.0371 0.0366
Entamoeba histolytica protein kinase, putative 0.0189 0.0201 0.0673
Schistosoma mansoni serine/threonine protein kinase 0.0854 0.186 0.1856
Echinococcus multilocularis epidermal growth factor receptor 0.1205 0.2734 0.2731
Echinococcus granulosus cathepsin L cysteine proteinase 0.1194 0.2707 0.2704
Schistosoma mansoni protein kinase C mu 0.0122 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus granulosus hypothetical protein 0.0257 0.0371 0.0366
Toxoplasma gondii AGC kinase 0.0292 0.0459 0.1605
Brugia malayi cathepsin F-like cysteine proteinase 0.0379 0.0676 0.0659
Entamoeba histolytica protein kinase, putative 0.0199 0.0226 0.0765
Giardia lamblia Cathepsin L precursor 0.0281 0.0432 0.1722
Echinococcus multilocularis acetylcholinesterase 0.0138 0.0074 0.0069
Onchocerca volvulus 0.0537 0.107 0.3912
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0293 0.0461 0.1613
Echinococcus multilocularis G-protein coupled receptor, putative 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Brugia malayi Sex muscle abnormal protein 5 0.0176 0.0169 0.0151
Brugia malayi Immunoglobulin I-set domain containing protein 0.0127 0.0048 0.003
Trichomonas vaginalis AGC family protein kinase 0.0538 0.1073 0.3961
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1069 0.2395 0.2391
Echinococcus multilocularis mitogen activated protein kinase 14 0.0587 0.1193 0.1189
Echinococcus granulosus serine threonine protein kinase nrc 0.0457 0.0871 0.0866
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0257 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0098 0.0093
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trypanosoma brucei SNF1-related protein kinases, putative 0.0262 0.0383 0.1171
Echinococcus granulosus tyrosine protein kinase Src42A 0.0278 0.0423 0.0418
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0453 0.086 0.0856
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0222 0.0284 0.0279
Loa Loa (eye worm) acetylcholinesterase 1 0.0138 0.0074 0.0069
Loa Loa (eye worm) melatonin receptor type 1A 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0239 0.0326 0.12
Loa Loa (eye worm) G-protein coupled receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0204 0.0239 0.0693
Entamoeba histolytica cysteine proteinase, putative 0.1194 0.2707 1
Onchocerca volvulus 0.0404 0.0737 0.2675
Plasmodium vivax vivapain-2 0.1194 0.2707 1
Plasmodium falciparum cGMP-dependent protein kinase 0.0295 0.0466 0.1632
Giardia lamblia Kinase, CK1 Casein kinase 0.0318 0.0523 0.2198
Schistosoma mansoni neuropeptide F-like receptor 0.0257 0.0371 0.0366
Schistosoma mansoni cell adhesion molecule 0.0243 0.0336 0.0331
Schistosoma mansoni serine/threonine protein kinase 0.0586 0.1191 0.1187
Brugia malayi Protein kinase domain containing protein 0.0207 0.0248 0.023
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0303 0.0487 0.1711
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0317 0.0521 0.0516
Onchocerca volvulus 0.0207 0.0248 0.0853
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0252 0.0359 0.0354
Echinococcus granulosus Glutaredoxin protein 5 0.036 0.0628 0.0623
Onchocerca volvulus 0.0257 0.0371 0.1311
Loa Loa (eye worm) TK/INSR protein kinase 0.0889 0.1947 0.1943
Loa Loa (eye worm) hypothetical protein 0.0281 0.0432 0.0427
Trichomonas vaginalis CK1 family protein kinase 0.0318 0.0523 0.1928
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0317 0.0521 0.0504
Echinococcus multilocularis dual specificity 0.0303 0.0487 0.0482
Schistosoma mansoni ste20-related kinase 0.0598 0.1223 0.1218
Brugia malayi Protein kinase domain containing protein 0.0654 0.1361 0.1345
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0303 0.0487 0.047
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0127 0.0048 0.0043
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0542 0.1082 0.1078
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Echinococcus multilocularis casein kinase I delta 0.0318 0.0523 0.0518
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Brugia malayi casein kinase 1, delta 0.0318 0.0523 0.0506
Echinococcus multilocularis casein kinase i 0.0318 0.0523 0.0518
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0648 0.1347 0.1342
Brugia malayi SH2 domain containing protein 0.0207 0.0248 0.023
Brugia malayi Dopamine receptor 0.0257 0.0371 0.0353
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0788 0.1695 0.1691
Schistosoma mansoni hypothetical protein 0.017 0.0154 0.0149
Onchocerca volvulus Cathepsin L homolog 0.1194 0.2707 1
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0485 0.0939 0.0935
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Echinococcus granulosus tyrosine kinase 0.0207 0.0248 0.0243
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1194 0.2707 0.2704
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Loa Loa (eye worm) hypothetical protein 0.0416 0.0767 0.0762
Trypanosoma cruzi cysteine peptidase, putative 0.1334 0.3057 0.5486
Brugia malayi Protein kinase domain containing protein 0.0267 0.0396 0.0379
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0246 0.0345 0.034
Giardia lamblia Kinase, CMGC CDK 0.0347 0.0597 0.2583
Echinococcus multilocularis g protein coupled receptor 0.0257 0.0371 0.0366
Brugia malayi Protein kinase domain containing protein 0.1102 0.2479 0.2466
Onchocerca volvulus 0.1194 0.2707 1
Echinococcus granulosus NDR protein kinase 0.0477 0.0919 0.0915
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0351 0.0606 0.0601
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0317 0.0521 0.1837
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0469 0.0901 0.3256
Echinococcus granulosus peptide allatostatin:somatostatin 0.0257 0.0371 0.0366
Schistosoma mansoni tyrosine kinase 0.0453 0.086 0.0856
Echinococcus multilocularis activin receptor type 0.0558 0.1123 0.1118
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0587 0.1193 0.211
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Echinococcus multilocularis geminin 0.017 0.0154 0.0149
Entamoeba histolytica hypothetical protein 0.0738 0.1571 0.577
Plasmodium falciparum serine repeat antigen 5 0.0281 0.0432 0.1504
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0513 0.101 0.1005
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0993 0.2206 0.2203
Schistosoma mansoni protein kinase 0.0189 0.0201 0.0197
Echinococcus granulosus dual specificity 0.0303 0.0487 0.0482
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0281 0.0432 0.1504
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0427 0.0795 0.0791
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0925 0.2037 0.2033
Trichomonas vaginalis STE family protein kinase 0.0252 0.0359 0.1321
Echinococcus granulosus tissue type plasminogen activator 0.036 0.0628 0.0623
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0209 0.0253 0.0248
Brugia malayi cathepsin L precursor 0.0281 0.0432 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0281 0.0432 0.1592
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0591 0.1203 0.1199
Schistosoma mansoni serine/threonine protein kinase 0.0477 0.0919 0.0915
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Echinococcus multilocularis Immunoglobulin 0.0165 0.0142 0.0138
Schistosoma mansoni protein kinase 0.0772 0.1656 0.1652
Echinococcus granulosus carboxylesterase 5A 0.0138 0.0074 0.0069
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0257 0.0371 0.0366
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Schistosoma mansoni serine/threonine protein kinase 0.0721 0.1529 0.1525
Schistosoma mansoni biogenic amine (5HT) receptor 0.0375 0.0665 0.0661
Schistosoma mansoni ephrin receptor 0.0292 0.046 0.0455
Brugia malayi cathepsin F-like cysteine proteinase 0.0281 0.0432 0.0415
Echinococcus granulosus cGMP dependent protein kinase 1 0.0295 0.0466 0.0461
Trypanosoma cruzi p21-activated kinase 3, putative 0.0161 0.0131 0.0185
Echinococcus multilocularis G protein coupled receptor 139 0.0257 0.0371 0.0366
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.0487 0.1737
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0222 0.0284 0.0266
Trypanosoma cruzi casein kinase, putative 0.0318 0.0523 0.0895
Plasmodium falciparum protein kinase 5 0.0347 0.0597 0.2119
Echinococcus granulosus g-protein coupled receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Toxoplasma gondii CMGC kinase, CK2 family 0.0293 0.0461 0.1613
Brugia malayi Serotonin receptor 0.0257 0.0371 0.0353
Echinococcus granulosus casein kinase I delta 0.0318 0.0523 0.0518
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0969 0.2147 0.2143
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0245 0.0342 0.0568
Brugia malayi Egg laying defective protein 4 0.0295 0.0466 0.0449
Brugia malayi Protein kinase domain containing protein 0.0243 0.0338 0.032
Loa Loa (eye worm) hypothetical protein 0.0123 0.0038 0.0033
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0427 0.0795 0.0779
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0224 0.029 0.0285
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0379 0.0676 0.0659
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0257 0.0371 0.0366
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0292 0.0459 0.0779
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0353 0.061 0.2169
Loa Loa (eye worm) hypothetical protein 0.0206 0.0246 0.0241
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0453 0.086 0.0856
Brugia malayi cyclin-dependent kinase 7 homolog 0.018 0.0179 0.0161
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0449 0.0849 0.1486
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0127 0.0048 0.0043
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0209 0.0253 0.0248
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0103 0.0376
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0485 0.0939 0.3466
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0281 0.0432 0.1592
Brugia malayi ephrin receptor 1 precursor 0.0194 0.0214 0.0197
Brugia malayi Protein kinase domain containing protein 0.0207 0.0248 0.023
Loa Loa (eye worm) cathepsin B 0.0916 0.2014 0.201
Brugia malayi Protein kinase domain containing protein 0.0153 0.0113 0.0095
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.08 0.1725 0.1721
Schistosoma mansoni protein kinase C mu 0.0635 0.1313 0.1309
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0295 0.0466 0.1632
Echinococcus multilocularis nervana 2 0.036 0.0628 0.0623
Echinococcus granulosus TGF-beta receptor type-1 0.0167 0.0147 0.0142
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0317 0.0521 0.0516
Brugia malayi Carboxylesterase family protein 0.0138 0.0074 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.0459 0.0454
Loa Loa (eye worm) hypothetical protein 0.0144 0.0089 0.0084
Trichomonas vaginalis AGC family protein kinase 0.012 0.0029 0.0103
Brugia malayi hypothetical protein 0.0325 0.0541 0.0524
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Entamoeba histolytica protein kinase domain containing protein 0.0427 0.0795 0.2884
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0469 0.0901 0.4176
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0387 0.0695 0.27
Loa Loa (eye worm) hypothetical protein 0.0256 0.0369 0.0365
Schistosoma mansoni serine/threonine protein kinase 0.0208 0.0249 0.0244
Entamoeba histolytica protein kinase, putative 0.0425 0.079 0.2864
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Entamoeba histolytica protein kinase domain containing protein 0.0376 0.0668 0.241
Plasmodium falciparum NIMA related kinase 1 0.0398 0.0722 0.2589
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0281 0.0432 0.1531
Echinococcus multilocularis protein kinase c eta type 0.0122 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis cathepsin b 0.2333 0.5548 0.5546
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0425 0.079 0.2842
Trichomonas vaginalis AGC family protein kinase 0.0484 0.0938 0.3463
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0206 0.0246 0.0241
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0113 0.0413
Schistosoma mansoni rap gtpase-activating protein 0.0325 0.0541 0.0537
Schistosoma mansoni protein kinase 0.0252 0.0359 0.0354
Echinococcus multilocularis dual specificity 0.0303 0.0487 0.0482
Brugia malayi Protein kinase domain containing protein 0.0466 0.0892 0.0876
Brugia malayi Protein kinase domain containing protein 0.0514 0.1012 0.0996
Echinococcus multilocularis netrin receptor unc 5 0.0126 0.0044 0.0039
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0648 0.1347 0.1342
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0127 0.0048 0.0043
Loa Loa (eye worm) hypothetical protein 0.0334 0.0563 0.0558
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0245 0.0342 0.117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Schistosoma mansoni serine/threonine protein kinase 0.0591 0.1203 0.1199
Loa Loa (eye worm) AUR protein kinase 0.0425 0.079 0.0786
Schistosoma mansoni titin 0.0183 0.0188 0.0183
Schistosoma mansoni protein kinase 0.0656 0.1366 0.1362
Loa Loa (eye worm) hypothetical protein 0.0404 0.0737 0.0733
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0223 0.0286 0.0281
Onchocerca volvulus 0.0416 0.0767 0.2784
Entamoeba histolytica cysteine proteinase 2 0.066 0.1377 0.5049
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0487 0.1796
Echinococcus granulosus netrin receptor unc 5 0.0126 0.0044 0.0039
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0357 0.0622 0.1074
Echinococcus granulosus tyrosine protein kinase Src64B 0.0453 0.086 0.0856
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0457 0.0871 0.3144
Brugia malayi Immunoglobulin I-set domain containing protein 0.0127 0.0048 0.003
Schistosoma mansoni protein kinase C 0.0125 0.0043 0.0038
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0183 0.0188 0.0183
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0398 0.0722 0.2589
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0103 0.0376
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0398 0.0723 0.2667
Trypanosoma cruzi cdc2-related kinase 1 0.0347 0.0597 0.1029
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0925 0.2037 0.2033
Entamoeba histolytica protein kinase, putative 0.0208 0.0249 0.0849
Schistosoma mansoni nephrin 0.0127 0.0048 0.0043
Plasmodium vivax serine-repeat antigen (SERA) 0.0281 0.0432 0.1504
Echinococcus granulosus acetylcholinesterase 0.0138 0.0074 0.0069
Loa Loa (eye worm) hypothetical protein 0.036 0.0628 0.0623
Giardia lamblia Kinase, AGC PKA 0.0457 0.0871 0.4019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0257 0.0371 0.0366
Echinococcus granulosus tyrosine protein kinase Fyn 0.0453 0.086 0.0856
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0969 0.2147 0.2132
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Trypanosoma cruzi hypothetical protein, conserved 0.036 0.0628 0.1085
Echinococcus multilocularis cathepsin L cysteine protease 0.1194 0.2707 0.2704
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0453 0.086 0.0856
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0427 0.0795 0.0791
Schistosoma mansoni protein kinase 0.1286 0.2937 0.2933
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Onchocerca volvulus 0.0257 0.0371 0.1311
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.066 0.1377 0.5084
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0457 0.0871 0.1526
Schistosoma mansoni hypothetical protein 0.0325 0.0541 0.0537
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0873 0.1907 0.1903
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0325 0.0541 0.0537
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.016 0.0155
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.066 0.1377 0.1373
Schistosoma mansoni hypothetical protein 0.0257 0.0372 0.0367
Schistosoma mansoni amine GPCR 0.0257 0.0371 0.0366
Giardia lamblia Cathepsin B precursor 0.0281 0.0432 0.1722
Echinococcus granulosus 7tm_1 domain containing protein 0.0257 0.0371 0.0366
Onchocerca volvulus 0.0257 0.0371 0.1311
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0318 0.0523 0.0518
Giardia lamblia Cathepsin L precursor 0.0281 0.0432 0.1722
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0586 0.1191 0.1186
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0176 0.0169 0.0164
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0317 0.0521 0.1837
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0165 0.0142 0.0138
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.4119 1 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0208 0.0249 0.0244
Leishmania major protein kinase, putative 0.0317 0.0521 0.1625
Entamoeba histolytica casein kinase, putative 0.0318 0.0523 0.187
Entamoeba histolytica serine/threonine protein kinase, putative 0.0149 0.0103 0.0306
Schistosoma mansoni vam6/vps39 related 0.0325 0.0541 0.0537
Echinococcus granulosus growth factor receptor bound protein 2 0.0181 0.0183 0.0178
Loa Loa (eye worm) hypothetical protein 0.0154 0.0116 0.0111
Trichomonas vaginalis AGC family protein kinase 0.0516 0.1018 0.3758
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.0597 0.0592
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0317 0.0521 0.0516
Brugia malayi Protein kinase domain containing protein 0.0858 0.1871 0.1856
Brugia malayi Protein kinase domain containing protein 0.1069 0.2395 0.2381
Brugia malayi RhoGEF domain containing protein 0.0122 0.0034 0.0016
Entamoeba histolytica protein kinase, putative 0.0277 0.0422 0.1494
Brugia malayi Protein kinase domain containing protein 0.0207 0.0248 0.023
Giardia lamblia Kinase, CAMK CAMKL 0.0269 0.0402 0.1568
Echinococcus granulosus tyrosine protein kinase Blk 0.0378 0.0674 0.0669
Loa Loa (eye worm) hypothetical protein 0.0815 0.1762 0.1758
Echinococcus granulosus mitogen activated protein kinase 3 0.0245 0.0342 0.0337
Loa Loa (eye worm) AGC/PKG protein kinase 0.0295 0.0466 0.0461
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0318 0.0523 0.0518
Loa Loa (eye worm) raf kinase 0.0122 0.0034 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0299 0.0294
Brugia malayi Kringle domain containing protein 0.036 0.0628 0.0611
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0376 0.0668 0.1158
Schistosoma mansoni serine/threonine-protein kinase 0.0479 0.0926 0.0921
Giardia lamblia Cathepsin L precursor 0.0281 0.0432 0.1722
Brugia malayi SH2 domain containing protein 0.0796 0.1716 0.1701
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.016 0.0155
Brugia malayi Protein kinase domain containing protein 0.0207 0.0248 0.023
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0295 0.0466 0.0461
Giardia lamblia Kinase, CDC7 0.0153 0.0113 0.0053
Loa Loa (eye worm) hypothetical protein 0.0466 0.0892 0.0887
Echinococcus granulosus biogenic amine 5HT receptor 0.0257 0.0371 0.0366
Onchocerca volvulus 0.0318 0.0523 0.1877
Entamoeba histolytica protein kinase domain containing protein 0.0204 0.0239 0.0812
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Leishmania major cathepsin L-like protease 0.1334 0.3057 1
Trichomonas vaginalis CMGC family protein kinase 0.0347 0.0597 0.22
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Brugia malayi Ras association domain family 1 isoform A 0.0122 0.0034 0.0016
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0449 0.0849 0.0845
Echinococcus granulosus neuropeptide receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0115 0.0018 0.0013
Echinococcus granulosus aurora kinase A 0.0425 0.079 0.0786
Schistosoma mansoni hypothetical protein 0.0257 0.0372 0.0367
Onchocerca volvulus 0.0993 0.2205 0.8134
Schistosoma mansoni protein kinase 0.0204 0.0239 0.0234
Echinococcus multilocularis fmrfamide receptor 0.0257 0.0371 0.0366
Echinococcus granulosus cyclin dependent kinase 9 0.0149 0.0102 0.0097
Loa Loa (eye worm) fibroinase 0.1194 0.2707 0.2704
Onchocerca volvulus 0.0257 0.0371 0.1311
Entamoeba histolytica protein kinase 2, putative 0.0457 0.0871 0.3165
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0257 0.0371 0.0366
Echinococcus granulosus contactin 0.0127 0.0048 0.0043
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0673 0.1408 0.1404
Plasmodium falciparum casein kinase 2, alpha subunit 0.0293 0.0461 0.1613
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0113 0.0413
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.066 0.1377 0.2443
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0449 0.0849 0.1486
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0281 0.0432 0.0427
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0591 0.1203 0.1199
Brugia malayi Protein kinase domain containing protein 0.0889 0.1947 0.1932
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0587 0.1193 0.211
Schistosoma mansoni diacylglycerol kinase theta 0.0122 0.0034 0.0029
Echinococcus multilocularis epidermal growth factor receptor 0.08 0.1725 0.1721
Entamoeba histolytica PH domain containing protein kinase, putative 0.0314 0.0514 0.1836
Giardia lamblia Cysteine protease 0.0281 0.0432 0.1722
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0199 0.0226 0.0765
Brugia malayi Fibronectin type III domain containing protein 0.0201 0.0233 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0383 0.0379
Onchocerca volvulus 0.0257 0.0371 0.1311
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0292 0.0459 0.0779
Echinococcus multilocularis calcium dependent protein kinase 0.0219 0.0278 0.0273
Echinococcus multilocularis neuroglian 0.0127 0.0048 0.0043
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0916 0.2014 0.3597
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0477 0.0919 0.0915
Brugia malayi serine/threonine-protein kinase 6 0.0425 0.079 0.0773
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0292 0.0459 0.0441
Onchocerca volvulus Serine\/threonine kinase homolog 0.0788 0.1695 0.6236
Brugia malayi Cathepsin L-like precursor 0.0379 0.0676 0.0659
Schistosoma mansoni cathepsin F (C01 family) 0.1194 0.2707 0.2704
Brugia malayi protein kinase C II. 0.0602 0.1232 0.1216
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0673 0.1408 0.1404
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0257 0.0371 0.0366
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0542 0.1082 0.1078
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0425 0.079 0.2864
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0376 0.0668 0.0664
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Trichomonas vaginalis AGC family protein kinase 0.0425 0.079 0.2915
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0208 0.0249 0.0244
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0485 0.0939 0.3466
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0204 0.0239 0.038
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0149 0.0103 0.0244
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0378 0.0674 0.0669
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0342 0.126
Echinococcus multilocularis expressed protein 0.0243 0.0338 0.0333
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0383 0.0379
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Echinococcus granulosus hypothetical protein 0.0351 0.0606 0.0601
Leishmania major cathepsin L-like protease 0.1194 0.2707 0.8846
Brugia malayi Serotonin receptor 0.0257 0.0371 0.0353
Entamoeba histolytica protein kinase, putative 0.012 0.0029 0.0031
Echinococcus multilocularis neuroglian 0.0215 0.0266 0.0261
Brugia malayi Protein kinase domain containing protein 0.0207 0.0248 0.023
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0453 0.086 0.0856
Trichomonas vaginalis CAMK family protein kinase 0.0796 0.1714 0.633
Brugia malayi hypothetical protein 0.0648 0.1347 0.1331
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0127 0.0048 0.0043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0815 0.1762 0.1758
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2742 0.6567 0.6565
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Echinococcus granulosus activin receptor type 0.0558 0.1123 0.1118
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0376 0.0668 0.0664
Schistosoma mansoni unc-13 (munc13) 0.0125 0.0043 0.0038
Trypanosoma cruzi major cysteine proteinase, putative 0.0281 0.0432 0.073
Trypanosoma cruzi cysteine peptidase, putative 0.0379 0.0676 0.1172
Echinococcus granulosus rho-associated protein kinase 1 0.0948 0.2093 0.2089
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0194 0.0216 0.0211
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0204 0.0239 0.038
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Schistosoma mansoni protein kinase 0.0656 0.1366 0.1362
Echinococcus granulosus cGMP dependent protein kinase 0.0295 0.0466 0.0461
Trichomonas vaginalis CAMK family protein kinase 0.0369 0.0652 0.2403
Echinococcus multilocularis casein kinase I alpha 0.0318 0.0523 0.0518
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Schistosoma mansoni serine/threonine protein kinase 0.0355 0.0615 0.061
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0281 0.0432 0.1504
Schistosoma mansoni serine/threonine protein kinase 0.0744 0.1585 0.158
Onchocerca volvulus 0.0153 0.0113 0.0352
Loa Loa (eye worm) RasGEF domain-containing protein 0.0122 0.0034 0.0029
Onchocerca volvulus 0.1194 0.2707 1
Schistosoma mansoni serine/threonine protein kinase 0.0355 0.0615 0.061
Brugia malayi map kinase activated protein kinase protein 2 0.1148 0.2594 0.2581
Loa Loa (eye worm) hypothetical protein 0.0537 0.107 0.1066
Echinococcus granulosus Immunoglobulin 0.0165 0.0142 0.0138
Brugia malayi cathepsin L-like precursor 0.0815 0.1762 0.1747
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2333 0.5548 0.5546
Echinococcus multilocularis cyclin dependent kinase 7 0.0172 0.016 0.0155
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Brugia malayi protein kinase C3,putative 0.046 0.0879 0.0862
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0281 0.0432 0.0427
Plasmodium vivax calcium-dependent protein kinase, putative 0.0317 0.0521 0.1837
Brugia malayi diacylglycerol kinase 0.0122 0.0034 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Schistosoma mansoni protein kinase 0.0167 0.0147 0.0142
Onchocerca volvulus 0.0948 0.2093 0.7716
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0815 0.1762 0.6508
Entamoeba histolytica protein kinase, putative 0.0252 0.0359 0.1259
Plasmodium falciparum serine repeat antigen 9 0.0281 0.0432 0.1504
Loa Loa (eye worm) hypothetical protein 0.0127 0.0048 0.0043
Echinococcus granulosus serine:threonine protein kinase 3 0.0749 0.1598 0.1594
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0303 0.0487 0.1514
Giardia lamblia Encystation-specific protease 0.0353 0.061 0.2653
Echinococcus granulosus neuropeptide receptor A26 0.0257 0.0371 0.0366
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0281 0.0432 0.1592
Trichomonas vaginalis AGC family protein kinase 0.012 0.0029 0.0103
Leishmania major cathepsin L-like protease 0.1194 0.2707 0.8846
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0262 0.0383 0.0642
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1307 0.2988 0.2985
Brugia malayi Papain family cysteine protease containing protein 0.1194 0.2707 0.2694
Echinococcus multilocularis tyrosine protein kinase Abl 0.036 0.0628 0.0623
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Loa Loa (eye worm) AUR protein kinase 0.0425 0.079 0.0786
Echinococcus granulosus tyrosine protein kinase 0.0572 0.1156 0.1152
Schistosoma mansoni protein kinase 0.0318 0.0523 0.0518
Schistosoma mansoni hypothetical protein 0.0257 0.0371 0.0366
Loa Loa (eye worm) TK protein kinase 0.0695 0.1464 0.146
Plasmodium falciparum serine repeat antigen 1 0.0281 0.0432 0.1504
Echinococcus multilocularis serine:threonine protein kinase 0.0334 0.0563 0.0558
Schistosoma mansoni protein kinase 0.0425 0.079 0.0786
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0721 0.1529 0.1525
Echinococcus granulosus tyrosine protein kinase shark 0.0622 0.1281 0.1277
Trypanosoma brucei NIMA-related protein kinase 0.0149 0.0103 0.0244
Brugia malayi Papain family cysteine protease containing protein 0.066 0.1377 0.1361
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0103 0.0376
Brugia malayi Cathepsin L-like precursor 0.1194 0.2707 0.2694
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Brugia malayi C1-like domain containing protein 0.0635 0.1313 0.1298
Onchocerca volvulus 0.0257 0.0371 0.1311
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0262 0.0383 0.0379
Echinococcus granulosus tm gpcr rhodopsin 0.0257 0.0371 0.0366
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Schistosoma mansoni tyrosine kinase 0.0168 0.015 0.0145
Echinococcus granulosus casein kinase I delta 0.0318 0.0523 0.0518
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Entamoeba histolytica protein kinase, putative 0.0243 0.0338 0.118
Entamoeba histolytica cysteine proteinase, putative 0.0815 0.1762 0.6482
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Schistosoma mansoni neuroglian 0.0127 0.0048 0.0043
Brugia malayi G protein-coupled receptor F59B2.13 0.0257 0.0371 0.0353
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0257 0.0371 0.0366
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0157 0.0122 0.0117
Schistosoma mansoni protein kinase 0.1069 0.2395 0.2391
Onchocerca volvulus 0.0376 0.0668 0.2417
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Entamoeba histolytica protein kinase, putative 0.0357 0.0622 0.2237
Treponema pallidum replicative DNA helicase (dnaB) 0.0387 0.0695 1
Plasmodium falciparum protein serine/threonine kinase-1 0.0449 0.0849 0.3063
Schistosoma mansoni diacylglycerol kinase theta 0.0122 0.0034 0.0029
Brugia malayi Protein kinase domain containing protein 0.0567 0.1145 0.1129
Toxoplasma gondii diacylglycerol kinase, putative 0.0122 0.0034 0.002
Giardia lamblia Kinase, CMGC SRPK 0.0243 0.0338 0.1229
Trichomonas vaginalis AGC family protein kinase 0.0239 0.0326 0.12
Entamoeba histolytica protein kinase, putative 0.0243 0.0338 0.118
Schistosoma mansoni serine/threonine protein kinase 0.0788 0.1695 0.1691
Loa Loa (eye worm) hypothetical protein 0.0257 0.0372 0.0367
Schistosoma mansoni nck2/grb4 0.0176 0.0169 0.0164
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Brugia malayi probable protein kinase 0.0772 0.1656 0.1641
Loa Loa (eye worm) TK/FAK protein kinase 0.1102 0.2479 0.2476
Brugia malayi cell division control protein 2 homolog 0.0347 0.0597 0.058
Schistosoma mansoni serine/threonine protein kinase 0.4119 1 1
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0248 0.0349 0.1222
Toxoplasma gondii AGC kinase 0.0292 0.0459 0.1605
Schistosoma mansoni cathepsin F (C01 family) 0.0815 0.1762 0.1758
Giardia lamblia Kinase, CMGC CK2 0.0293 0.0461 0.1874
Trichomonas vaginalis STE family protein kinase 0.0149 0.0103 0.0376
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Echinococcus multilocularis RNA directed DNA polymerase 0.0115 0.0018 0.0013
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0656 0.1366 0.1362
Giardia lamblia Kinase, NEK 0.0398 0.0722 0.3241
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0137 0.0073 0.0265
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0376 0.0668 0.0664
Echinococcus granulosus dual specificity 0.0357 0.0622 0.0617
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0487 0.1796
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0113 0.0108
Trypanosoma brucei Casein kinase II 0.0293 0.0461 0.1427
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0257 0.0371 0.0366
Schistosoma mansoni rac gtpase activating protein 0.0122 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.0281 0.0432 0.0427
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0208 0.0249 0.0244
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Brugia malayi Protein kinase domain containing protein 0.0993 0.2205 0.2191
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.0459 0.0454
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0137 0.0073 0.0265
Echinococcus granulosus protein kinase C gamma type 0.0596 0.1216 0.1212
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0485 0.0939 0.3466
Loa Loa (eye worm) IKK protein kinase 0.0993 0.2205 0.2202
Brugia malayi STE20-like kinase MST 0.0749 0.1598 0.1582
Echinococcus multilocularis tyrosine protein kinase shark 0.0622 0.1281 0.1277
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Schistosoma mansoni biogenic amine receptor 0.0257 0.0371 0.0366
Schistosoma mansoni unc-13 (munc13) 0.0125 0.0043 0.0038
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0257 0.0371 0.0366
Giardia lamblia Cathepsin L precursor 0.0281 0.0432 0.1722
Entamoeba histolytica protein kinase, putative 0.0211 0.0256 0.0878
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1221 0.2775 0.2772
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0207 0.0248 0.0845
Trichomonas vaginalis conserved hypothetical protein 0.0281 0.0432 0.1592
Giardia lamblia Cathepsin B precursor 0.0281 0.0432 0.1722
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0411 0.0755 0.075
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0137 0.0073 0.0265
Echinococcus granulosus serotonin receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) TK protein kinase 0.0637 0.1318 0.1314
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0257 0.0371 0.0366
Echinococcus multilocularis ephrin type A receptor 4 A 0.0292 0.046 0.0455
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0281 0.0432 0.1504
Echinococcus multilocularis casein kinase I delta 0.0318 0.0523 0.0518
Loa Loa (eye worm) hypothetical protein 0.0346 0.0594 0.0589
Loa Loa (eye worm) ctsf protein 0.1194 0.2707 0.2704
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0161 0.0131 0.0481
Brugia malayi Tyrosine-protein kinase abl-1 0.0126 0.0044 0.0026
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0425 0.079 0.2864
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0141 0.0083 0.0078
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0516 0.1018 0.1014
Echinococcus granulosus tyrosine protein kinase Fyn 0.0453 0.086 0.0856
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.0992 0.0987
Giardia lamblia Kinase, CMGC MAPK 0.0245 0.0342 0.1253
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0347 0.0597 0.0592
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0342 0.0584 0.0567
Brugia malayi Temporarily assigned gene name protein 59 0.0375 0.0666 0.065
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0457 0.0871 0.0866
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0873 0.1907 0.1903
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0338 0.0333
Brugia malayi sulfakinin receptor protein 0.0257 0.0371 0.0353
Entamoeba histolytica cysteine protease, putative 0.0281 0.0432 0.1531
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0685 0.1439 0.1435
Onchocerca volvulus 0.0207 0.0248 0.0853
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Loa Loa (eye worm) hypothetical protein 0.0237 0.0322 0.0317
Schistosoma mansoni vav2 0.0245 0.0341 0.0336
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0257 0.0371 0.0366
Echinococcus granulosus N chimaerin 0.0223 0.0286 0.0281
Onchocerca volvulus 0.0257 0.0371 0.1311
Brugia malayi MH2 domain containing protein 0.0117 0.0023 0.0005
Entamoeba histolytica casein kinase, putative 0.0293 0.0461 0.1639
Echinococcus multilocularis cathepsin L 0.0281 0.0432 0.0427
Brugia malayi Casein kinase II, alpha chain 0.0293 0.0461 0.0444
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis serine:threonine protein kinase N2 0.0377 0.0671 0.0667
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.066 0.1377 0.1373
Schistosoma mansoni serine/threonine protein kinase 0.0317 0.0521 0.0516
Schistosoma mansoni serine/threonine protein kinase 0.0425 0.079 0.0786
Schistosoma mansoni protein kinase 0.0241 0.0332 0.0327
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0149 0.0103 0.0134
Echinococcus granulosus TGF beta receptor type 1 0.0167 0.0147 0.0142
Schistosoma mansoni tyrosine kinase 0.0694 0.1461 0.1456
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0469 0.0901 0.3256
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.066 0.1377 0.1373
Brugia malayi casein kinase I 0.0318 0.0523 0.0506
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0281 0.0432 0.1592
Echinococcus granulosus nervana 2 0.036 0.0628 0.0623
Echinococcus granulosus biogenic amine 5HT receptor 0.0375 0.0665 0.0661
Entamoeba histolytica hypothetical protein 0.0122 0.0034 0.0051
Onchocerca volvulus Neuropeptide F receptor homolog 0.0257 0.0371 0.1311
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Schistosoma mansoni histamine h1 receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0122 0.0034 0.0029
Loa Loa (eye worm) TK/EPH protein kinase 0.0343 0.0587 0.0582
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0602 0.1232 0.1227
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0241 0.0332 0.0549
Echinococcus multilocularis protein kinase shaggy 0.0376 0.0668 0.0664
Echinococcus multilocularis c Jun NH2 terminal kinase 0.4119 1 1
Onchocerca volvulus 0.0281 0.0432 0.1539
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0376 0.0668 0.2387
Echinococcus granulosus serine:threonine protein kinase 0.0334 0.0563 0.0558
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0257 0.0371 0.0366
Echinococcus granulosus NCK adaptor protein 0.0176 0.0169 0.0164
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0262 0.0383 0.1171
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0587 0.1194 0.119
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0303 0.0487 0.083
Schistosoma mansoni neuropeptide f receptor 76f 0.0257 0.0371 0.0366
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Trichomonas vaginalis CMGC family protein kinase 0.0449 0.0849 0.3134
Schistosoma mansoni protein kinase 0.0176 0.0169 0.0164
Echinococcus multilocularis cyclin dependent kinase 5 0.0347 0.0597 0.0592
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Entamoeba histolytica protein kinase, putative 0.0211 0.0256 0.0878
Brugia malayi cyclin-dependent kinase 9 0.0141 0.0083 0.0065
Giardia lamblia Kinase, CMGC DYRK 0.0303 0.0487 0.2011
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1194 0.2707 1
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0116 0.0423
Brugia malayi Papain family cysteine protease containing protein 0.066 0.1377 0.1361
Echinococcus multilocularis casein kinase ii subunit alpha 0.0293 0.0461 0.0456
Echinococcus multilocularis dual specificity mitogen activated protein 0.0241 0.0332 0.0327
Schistosoma mansoni hypothetical protein 0.0257 0.0371 0.0366
Brugia malayi Protein kinase domain containing protein 0.0506 0.0992 0.0975
Echinococcus granulosus neuropeptide FF receptor 2 0.0257 0.0371 0.0366
Schistosoma mansoni ephrin receptor 0.0142 0.0086 0.0081
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0281 0.0432 0.0427
Loa Loa (eye worm) neuropeptide F receptor 0.0257 0.0371 0.0366
Echinococcus granulosus expressed protein 0.0243 0.0338 0.0333
Brugia malayi RE15519p 0.0257 0.0371 0.0353
Entamoeba histolytica hypothetical protein 0.0357 0.0622 0.2237
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0453 0.086 0.0856
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0281 0.0432 0.1592
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0284 0.0279
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0648 0.1347 0.1342
Schistosoma mansoni tyrosine kinase 0.0587 0.1194 0.119
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0281 0.0432 0.1592
Schistosoma mansoni serine/threonine protein kinase 0.0591 0.1203 0.1199
Echinococcus granulosus 7TM GPCR rhodopsin 0.0257 0.0371 0.0366
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0281 0.0432 0.1531
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0357 0.0622 0.0617
Echinococcus multilocularis hypothetical protein 0.0257 0.0372 0.0367
Entamoeba histolytica protein kinase, putative 0.0858 0.1871 0.6887
Echinococcus multilocularis cysteine protease 0.1194 0.2707 0.2704
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Brugia malayi Cathepsin L-like precursor 0.0815 0.1762 0.1747
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0165 0.0142 0.0138
Toxoplasma gondii cathepsin CPC2 0.0353 0.061 0.2169
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0295 0.0466 0.0461
Brugia malayi Protein kinase domain containing protein 0.0572 0.1156 0.114
Echinococcus granulosus sex peptide receptor 0.0257 0.0371 0.0366
Onchocerca volvulus 0.1194 0.2707 1
Schistosoma mansoni atypical protein kinase C 0.0857 0.1868 0.1864
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0487 0.1796
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0262 0.0383 0.0379
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0165 0.0142 0.0138
Plasmodium falciparum calcium-dependent protein kinase 1 0.0317 0.0521 0.1837
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0281 0.0432 0.0427
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0149 0.0103 0.0134
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0161 0.0131 0.0126
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0281 0.0432 0.1592
Echinococcus multilocularis mitogen activated protein kinase 11 0.0587 0.1193 0.1189
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Schistosoma mansoni serine/threonine protein kinase 0.0295 0.0466 0.0461
Entamoeba histolytica PH domain containing protein kinase, putative 0.012 0.0029 0.0031
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0023 0.0019
Loa Loa (eye worm) hypothetical protein 0.0375 0.0665 0.0661
Echinococcus granulosus casein kinase ii subunit alpha 0.0293 0.0461 0.0456
Loa Loa (eye worm) twinkle helicase 0.011 0.0006 0.0001
Echinococcus granulosus roundabout 2 0.0292 0.046 0.0455
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0159 0.0128 0.0468
Brugia malayi Hr1 repeat family protein 0.0854 0.186 0.1845
Mycobacterium ulcerans hypothetical protein 0.0197 0.0223 0.3207
Onchocerca volvulus 0.1194 0.2707 1
Toxoplasma gondii NEK kinase 0.0149 0.0103 0.0276
Loa Loa (eye worm) CAMK protein kinase 0.0183 0.0188 0.0183
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Loa Loa (eye worm) gastrulation defective protein 1 0.0127 0.0047 0.0042
Toxoplasma gondii cathepsin B 0.0916 0.2014 0.7412
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.0372 0.1369
Echinococcus granulosus casein kinase I gamma 0.0506 0.0992 0.0987
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0383 0.0379
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Echinococcus multilocularis serine:threonine protein kinase 0.0334 0.0563 0.0558
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0209 0.0253 0.0248
Leishmania major protein kinase A catalytic subunit 0.0292 0.0459 0.142
Echinococcus granulosus myotubularin protein 13 0.0144 0.0089 0.0084
Plasmodium falciparum glycogen synthase kinase 3 0.0376 0.0668 0.2387
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Entamoeba histolytica protein kinase domain containing protein 0.0293 0.0461 0.1639
Trypanosoma cruzi casein kinase, putative 0.0318 0.0523 0.0895
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0342 0.0337
Plasmodium falciparum cysteine repeat modular protein 1 0.036 0.0628 0.2235
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0376 0.0668 0.0664
Entamoeba histolytica cysteine proteinase, putative 0.066 0.1377 0.5049
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Entamoeba histolytica protein kinase, putative 0.0317 0.0521 0.1862
Onchocerca volvulus 0.0257 0.0371 0.1311
Schistosoma mansoni serine/threonine protein kinase 0.0873 0.1907 0.1903
Leishmania major cathepsin L-like protease 0.1194 0.2707 0.8846
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0208 0.0249 0.0244
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0873 0.1907 0.1892
Echinococcus multilocularis cathepsin L cysteine protease 0.1194 0.2707 0.2704
Trichomonas vaginalis CAMK family protein kinase 0.0369 0.0652 0.2403
Leishmania major cathepsin L-like protease 0.1334 0.3057 1
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0237 0.0322 0.1096
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0717 0.1519 0.1515
Entamoeba histolytica PH domain containing protein kinase, putative 0.0479 0.0926 0.3369
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1862 0.4373 0.437
Onchocerca volvulus 0.0186 0.0195 0.0658
Schistosoma mansoni serine/threonine kinase 0.0522 0.1031 0.1027
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0257 0.0371 0.0366
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0257 0.0371 0.0353
Echinococcus multilocularis cyclin dependent kinase 9 0.0141 0.0083 0.0078
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.3391 0.8185 1
Trypanosoma cruzi aurora B kinase, putative 0.0425 0.079 0.1379
Echinococcus multilocularis aurora kinase A 0.0425 0.079 0.0786
Entamoeba histolytica protein kinase, putative 0.0357 0.0622 0.2237
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0353 0.061 0.2653
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0317 0.0521 0.0516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Echinococcus granulosus neuropeptide s receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) AGC/PKN protein kinase 0.0854 0.186 0.1856
Echinococcus multilocularis tissue type plasminogen activator 0.036 0.0628 0.0623
Schistosoma mansoni adapter molecule crk 0.0176 0.0169 0.0164
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0303 0.0487 0.0482
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Schistosoma mansoni nephrin 0.0251 0.0357 0.0352
Schistosoma mansoni neuropeptide receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis titin 0.0183 0.0188 0.0183
Schistosoma mansoni growth hormone secretagogue receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis serine:threonine protein kinase 3 0.0749 0.1598 0.1594
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0149 0.0103 0.0134
Loa Loa (eye worm) protein kinase domain-containing protein 0.0506 0.0992 0.0987
Loa Loa (eye worm) hypothetical protein 0.0122 0.0034 0.0029
Brugia malayi Variant SH3 domain containing protein 0.0176 0.0169 0.0151
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Entamoeba histolytica protein kinase domain containing protein 0.0141 0.0083 0.0232
Loa Loa (eye worm) hypothetical protein 0.026 0.0378 0.0374
Echinococcus granulosus tyrosine protein kinase Fyn 0.0453 0.086 0.0856
Plasmodium vivax serine/threonine protein kinase, putative 0.0243 0.0338 0.1153
Brugia malayi Protein kinase domain containing protein 0.0157 0.0122 0.0104
Echinococcus granulosus fibroblast growth factor receptor 4 0.0587 0.1194 0.119
Onchocerca volvulus Cathepsin L homolog 0.1194 0.2707 1
Echinococcus granulosus cathepsin b 0.2333 0.5548 0.5546
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0334 0.0563 0.0558
Echinococcus multilocularis fmrfamide receptor 0.0257 0.0371 0.0366
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0161 0.0131 0.0126
Loa Loa (eye worm) TK protein kinase 0.0277 0.0422 0.0417
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0317 0.0521 0.0516
Entamoeba histolytica protein kinase, putative 0.0321 0.053 0.1896
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0449 0.0849 0.1486
Trypanosoma brucei cdc2-related kinase 3 0.0347 0.0597 0.1875
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0487 0.0482
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0353 0.061 0.2653
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0478 0.0923 0.0918
Echinococcus granulosus activated cdc42 kinase 1 0.0267 0.0396 0.0391
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0586 0.1191 0.1187
Toxoplasma gondii cathepsin CPL 0.1194 0.2707 1
Echinococcus granulosus neuropeptide receptor 0.0257 0.0371 0.0366
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0317 0.0521 0.1837
Echinococcus granulosus cyclin dependent kinase 9 0.0141 0.0083 0.0078
Brugia malayi G protein-coupled receptor 0.0257 0.0371 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0281 0.0432 0.1592
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0815 0.1762 0.6508
Echinococcus multilocularis Glutaredoxin protein 5 0.036 0.0628 0.0623
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0209 0.0253 0.0235
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0325 0.0541 0.0928
Plasmodium vivax tyrosine kinase-like protein, putative 0.0237 0.0322 0.1096
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2333 0.5548 0.5546
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Echinococcus multilocularis neuropeptide receptor 0.0257 0.0371 0.0366
Brugia malayi p70 ribosomal S6 kinase beta 0.0836 0.1816 0.1801
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.1286 0.2937 0.2933
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.0372 0.1369
Echinococcus multilocularis NCK adaptor protein 0.0181 0.0183 0.0178
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Echinococcus granulosus casein kinase I alpha 0.0318 0.0523 0.0518
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Brugia malayi neuropeptide F receptor 0.0257 0.0371 0.0353
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Loa Loa (eye worm) hypothetical protein 0.0416 0.0767 0.0762
Loa Loa (eye worm) TK/EGFR protein kinase 0.1205 0.2734 0.2731
Schistosoma mansoni neuropeptide receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0293 0.0461 0.0456
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Echinococcus multilocularis serine:threonine protein kinase N2 0.0477 0.0919 0.0915
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0138 0.0074 0.0069
Echinococcus multilocularis serotonin receptor 0.0375 0.0665 0.0661
Schistosoma mansoni cell adhesion molecule 0.0127 0.0048 0.0043
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0243 0.0338 0.0333
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1194 0.2707 1
Plasmodium falciparum serine repeat antigen 6 0.0281 0.0432 0.1504
Toxoplasma gondii AGC kinase 0.0836 0.1816 0.6672
Brugia malayi Cathepsin L-like precursor 0.1194 0.2707 0.2694
Brugia malayi serine/threonine protein kinase 6 0.0425 0.079 0.0773
Trypanosoma cruzi cdc2-related kinase 1 0.0347 0.0597 0.1029
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis TGF beta receptor type 1 0.0167 0.0147 0.0142
Echinococcus multilocularis mitogen activated protein kinase 0.0245 0.0342 0.0337
Echinococcus multilocularis orexin receptor type 2 0.0257 0.0371 0.0366
Echinococcus granulosus cyclin dependent kinase 1 0.0347 0.0597 0.0592
Echinococcus granulosus protein tyrosine kinase 0.1091 0.245 0.2446
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Onchocerca volvulus 0.0815 0.1762 0.6486
Trypanosoma cruzi casein kinase, delta isoform, putative 0.022 0.028 0.0455
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0325 0.0541 0.0537
Echinococcus granulosus protein kinase c eta type 0.0122 0.0034 0.0029
Giardia lamblia Kinase, AGC PKA 0.0292 0.0459 0.1863
Loa Loa (eye worm) hypothetical protein 0.2333 0.5548 0.5546
Echinococcus granulosus unc 13 munc13 0.0125 0.0043 0.0038
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0303 0.0487 0.1514
Schistosoma mansoni tyrosine kinase 0.031 0.0503 0.0498
Plasmodium falciparum NIMA related kinase 2 0.0149 0.0103 0.0276
Loa Loa (eye worm) camk/dcamkl protein kinase 0.044 0.0829 0.0824
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0587 0.1193 0.3846
Trypanosoma cruzi polo-like protein kinase, putative 0.0788 0.1695 0.3019
Brugia malayi cathepsin B-like cysteine proteinase 0.2333 0.5548 0.554
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0453 0.086 0.0856
Loa Loa (eye worm) hypothetical protein 0.0262 0.0383 0.0379
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis neuropeptide receptor A26 0.0257 0.0371 0.0366
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Entamoeba histolytica protein kinase, putative 0.0303 0.0487 0.1737
Loa Loa (eye worm) hypothetical protein 0.0122 0.0034 0.0029
Entamoeba histolytica diacylglycerol kinase, putative 0.0122 0.0034 0.0051
Echinococcus granulosus tyrosine protein kinase Srms 0.0999 0.2221 0.2217
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Echinococcus multilocularis CDC7 cell division cycle 7 0.0153 0.0113 0.0108
Giardia lamblia Kinase, STE STE20 0.0248 0.0349 0.1288
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1194 0.2707 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0347 0.0597 0.0592
Echinococcus multilocularis dual specificity protein kinase clk2 0.0449 0.0849 0.0845
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0449 0.0849 0.3063
Giardia lamblia Kinase, CMGC CDK 0.0347 0.0597 0.2583
Schistosoma mansoni cathepsin s 0.0379 0.0676 0.0671
Echinococcus granulosus serine:threonine kinase SAD 1 0.0262 0.0383 0.0379
Loa Loa (eye worm) hypothetical protein 0.1194 0.2707 0.2704
Trypanosoma cruzi cruzipain precursor, putative 0.1334 0.3057 0.5486
Loa Loa (eye worm) hypothetical protein 0.0281 0.0432 0.0427
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0257 0.0371 0.0353
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0449 0.0849 0.0845
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0453 0.086 0.0856
Echinococcus multilocularis expressed conserved protein 0.0295 0.0466 0.0461
Leishmania major casein kinase II, putative 0.0293 0.0461 0.1427
Echinococcus multilocularis tyrosine kinase 0.0207 0.0248 0.0243
Trichomonas vaginalis CK1 family protein kinase 0.0318 0.0523 0.1928
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0453 0.086 0.0856
Echinococcus granulosus tyrosine protein kinase ABL1 0.0411 0.0755 0.075
Echinococcus granulosus epidermal growth factor receptor 0.1205 0.2734 0.2731
Schistosoma mansoni serine/threonine protein kinase 0.0357 0.0622 0.0617
Echinococcus multilocularis serine:threonine protein kinase 38 0.0477 0.0919 0.0915
Brugia malayi Cathepsin L-like precursor 0.1194 0.2707 0.2694
Schistosoma mansoni serine/threonine protein kinase 0.0602 0.1232 0.1227
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0257 0.0372 0.0367
Trichomonas vaginalis CK1 family protein kinase 0.0318 0.0523 0.1928
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0916 0.2014 0.201
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0281 0.0432 0.0415
Schistosoma mansoni serine/threonine protein kinase 0.0352 0.0609 0.0604
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus granulosus neuropeptides capa receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0342 0.126
Trichomonas vaginalis AGC family protein kinase 0.0398 0.0722 0.2665
Loa Loa (eye worm) AGC/NDR protein kinase 0.0477 0.0919 0.0915
Giardia lamblia Cysteine protease 0.0281 0.0432 0.1722
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0281 0.0432 0.0427
Brugia malayi serine/threonine kinase 12 0.0425 0.079 0.0773
Trypanosoma cruzi cysteine peptidase, putative 0.1334 0.3057 0.5486
Onchocerca volvulus 0.0207 0.0248 0.0853
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0125 0.0043 0.0038
Brugia malayi Variant SH3 domain containing protein 0.0223 0.0286 0.0269
Schistosoma mansoni opsin-like receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0347 0.0597 0.0592
Plasmodium vivax vivapain-2 0.1194 0.2707 1
Echinococcus multilocularis neuropeptide Y receptor 0.0257 0.0371 0.0366
Brugia malayi Protein kinase domain containing protein 0.0357 0.0622 0.0605
Schistosoma mansoni cathepsin B (C01 family) 0.0281 0.0432 0.0427
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Echinococcus granulosus g protein coupled receptor 0.0257 0.0371 0.0366
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0223 0.0286 0.0281
Leishmania major protein kinase, putative 0.0149 0.0103 0.0244
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Echinococcus granulosus tm gpcr rhodopsin 0.0257 0.0371 0.0366
Echinococcus granulosus calcium activated potassium channel 0.0355 0.0615 0.061
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0194 0.0216 0.0211
Echinococcus multilocularis allatostatin A receptor 0.0257 0.0371 0.0366
Schistosoma mansoni cathepsin F (C01 family) 0.1194 0.2707 0.2704
Entamoeba histolytica hypothetical protein 0.012 0.0029 0.0031
Schistosoma mansoni tyrosine kinase 0.0603 0.1235 0.1231
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0788 0.1695 0.5503
Brugia malayi RhoGAP domain containing protein 0.0122 0.0034 0.0016
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0243 0.0338 0.0559
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Loa Loa (eye worm) hypothetical protein 0.0176 0.0169 0.0164
Brugia malayi Protein kinase domain containing protein 0.0516 0.1018 0.1002
Plasmodium falciparum cysteine proteinase falcipain 1 0.066 0.1377 0.5033
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1194 0.2707 0.2704
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0423 0.0784 0.078
Entamoeba histolytica serine/threonine protein kinase, putative 0.0262 0.0383 0.135
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0245 0.0342 0.1035
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0262 0.0383 0.0642
Loa Loa (eye worm) hypothetical protein 0.0125 0.0043 0.0038
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0292 0.0459 0.0779
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0241 0.0332 0.1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0257 0.0371 0.0366
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0243 0.0338 0.102
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0514 0.1012 0.1008
Leishmania major protein kinase, putative 0.0425 0.079 0.2514
Echinococcus multilocularis 0.0447 0.0846 0.0841
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0149 0.0103 0.0244
Brugia malayi hypothetical protein 0.0207 0.0248 0.023
Plasmodium vivax unspecified product 0.0293 0.0461 0.1613
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0587 0.1194 0.119
Loa Loa (eye worm) hypothetical protein 0.0184 0.0189 0.0185
Entamoeba histolytica protein kinase, putative 0.0239 0.0326 0.1136
Entamoeba histolytica protein kinase, putative 0.0858 0.1871 0.6887
Brugia malayi ORL1-like opioid receptor 0.0257 0.0371 0.0353
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.1069 0.2395 0.2391
Brugia malayi G-protein coupled receptor 0.0257 0.0371 0.0353
Brugia malayi Carboxylesterase family protein 0.0138 0.0074 0.0056
Onchocerca volvulus 0.0257 0.0371 0.1311
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0469 0.0901 0.3256
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0685 0.1439 0.1435
Giardia lamblia Cysteine protease 0.0281 0.0432 0.1722
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0423 0.0785 0.0781
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Onchocerca volvulus Cathepsin F homolog 0.1194 0.2707 1
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0347 0.0597 0.0592
Brugia malayi Dopamine receptor protein 1 0.0257 0.0371 0.0353
Echinococcus granulosus Vam6:Vps39 protein 0.0325 0.0541 0.0537
Trypanosoma brucei cysteine peptidase C (CPC) 0.0916 0.2014 0.6557
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.069 0.1452 0.1447
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Echinococcus granulosus casein kinase i 0.0318 0.0523 0.0518
Onchocerca volvulus 0.0257 0.0371 0.1311
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Brugia malayi follicle stimulating hormone receptor 0.0257 0.0371 0.0353
Echinococcus multilocularis casein kinase I alpha 0.0318 0.0523 0.0518
Entamoeba histolytica PH domain containing protein kinase, putative 0.0479 0.0926 0.3369
Giardia lamblia Kinase, NEK 0.0398 0.0722 0.3241
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.029 0.0285
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0257 0.0371 0.0366
Schistosoma mansoni neuropeptide F-like receptor 0.0257 0.0371 0.0366
Brugia malayi protein-tyrosine kinase 0.0378 0.0674 0.0657
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0257 0.0371 0.0366
Trypanosoma brucei protein kinase, putative 0.0376 0.0668 0.2111
Loa Loa (eye worm) hypothetical protein 0.0228 0.03 0.0296
Echinococcus granulosus neuropeptide Y receptor 0.0257 0.0371 0.0366
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0243 0.0338 0.102
Toxoplasma gondii cathepsin CPC1 0.0469 0.0901 0.3256
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0281 0.0432 0.1592
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0209 0.0253 0.0248
Onchocerca volvulus 0.0207 0.0248 0.0853
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0425 0.079 0.0786
Echinococcus granulosus protein kinase c epsilon type 0.0602 0.1232 0.1227
Loa Loa (eye worm) hypothetical protein 0.0404 0.0737 0.0733
Echinococcus multilocularis growth factor receptor bound protein 2 0.0176 0.0169 0.0164
Trypanosoma cruzi cysteine peptidase, putative 0.1194 0.2707 0.4853
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0357 0.0622 0.1957
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0423 0.0785 0.0781
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Onchocerca volvulus 0.0125 0.0043 0.0094
Echinococcus multilocularis mitogen activated protein kinase 11 0.0587 0.1193 0.1189
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0347 0.0597 0.1875
Loa Loa (eye worm) hypothetical protein 0.0207 0.0248 0.0243
Schistosoma mansoni serine/threonine protein kinase 0.0427 0.0795 0.0791
Echinococcus granulosus mitogen activated protein kinase 14 0.0587 0.1193 0.1189
Schistosoma mansoni tyrosine kinase 0.1091 0.245 0.2446
Onchocerca volvulus 0.0257 0.0371 0.1311
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0252 0.0359 0.0354
Echinococcus multilocularis roundabout 2 0.0292 0.046 0.0455
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.144 0.3321 0.3317
Entamoeba histolytica cysteine proteinase 1, putative 0.066 0.1377 0.5049
Toxoplasma gondii NEK kinase 0.0149 0.0103 0.0276
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0836 0.1816 0.1812
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Schistosoma mansoni serine/threonine protein kinase 0.0717 0.1519 0.1515
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0292 0.0459 0.142
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0217 0.0271 0.0266
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2333 0.5548 0.5546
Loa Loa (eye worm) CDC7 protein kinase 0.0153 0.0113 0.0108
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0317 0.0521 0.0516
Echinococcus multilocularis tyrosine protein kinase Blk 0.0378 0.0674 0.0669
Echinococcus granulosus cyclin dependent kinase 0.0347 0.0597 0.0592
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0352 0.0609 0.0604
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0245 0.0342 0.1035
Loa Loa (eye worm) hypothetical protein 0.0815 0.1762 0.1758
Schistosoma mansoni hypothetical protein 0.0122 0.0034 0.0029
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0248 0.0349 0.058
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0112 0.0009 0.0004
Trichomonas vaginalis STE family protein kinase 0.0248 0.0349 0.1285
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0477 0.0919 0.0915
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Echinococcus granulosus cGMP dependent protein kinase 1 0.0295 0.0466 0.0461
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0447 0.0846 0.0841
Brugia malayi Protein kinase domain containing protein 0.0873 0.1907 0.1892
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0122 0.0034 0.0029
Echinococcus multilocularis cyclin dependent kinase 0.0347 0.0597 0.0592
Onchocerca volvulus 0.0207 0.0248 0.0853
Schistosoma mansoni amine GPCR 0.0257 0.0371 0.0366
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0241 0.0332 0.0314
Entamoeba histolytica cysteine proteinase, putative 0.066 0.1377 0.5049
Brugia malayi neuropeptide F receptor 0.0257 0.0371 0.0353
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Giardia lamblia Cathepsin B precursor 0.0916 0.2014 1
Leishmania major casein kinase, putative 0.0318 0.0523 0.1632
Loa Loa (eye worm) AGC/AKT protein kinase 0.0858 0.1871 0.1867
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0161 0.0131 0.0113
Trypanosoma cruzi cdc2-related kinase 3 0.0347 0.0597 0.1029
Schistosoma mansoni serine/threonine protein kinase 0.0542 0.1082 0.1078
Entamoeba histolytica diacylglycerol kinase, putative 0.0122 0.0034 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.0788 0.1695 0.626
Brugia malayi putative serine/threonine kinase SADA gamma 0.0262 0.0383 0.0366
Echinococcus multilocularis cyclin dependent kinase 1 0.0347 0.0597 0.0592
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Brugia malayi Kinase associated domain 1 family protein 0.0257 0.0372 0.0354
Echinococcus multilocularis nervana 2 0.036 0.0628 0.0623
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0204 0.0239 0.0783
Schistosoma mansoni hypothetical protein 0.017 0.0154 0.0149
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0103 0.0098
Echinococcus multilocularis myotubularin protein 13 0.0144 0.0089 0.0084
Schistosoma mansoni protein kinase 0.1286 0.2937 0.2933
Schistosoma mansoni tyrosine kinase 0.0694 0.1461 0.1456
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0325 0.0541 0.0537
Giardia lamblia Cysteine protease 0.0281 0.0432 0.1722
Schistosoma mansoni protein kinase 0.0563 0.1133 0.1129
Trypanosoma cruzi cysteine proteinase, putative 0.066 0.1377 0.2443
Plasmodium vivax unspecified product 0.0281 0.0432 0.1504
Schistosoma mansoni tyrosine kinase 0.0197 0.0223 0.0218
Toxoplasma gondii NEK kinase 0.0149 0.0103 0.0276
Trichomonas vaginalis CAMK family protein kinase 0.0788 0.1695 0.626
Toxoplasma gondii preprocathepsin c precursor, putative 0.0469 0.0901 0.3256
Giardia lamblia Kinase, CMGC GSK 0.0376 0.0668 0.2958
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0487 0.1796
Echinococcus granulosus Diacylglycerol kinase theta 0.0122 0.0034 0.0029
Echinococcus multilocularis calcium activated potassium channel 0.0355 0.0615 0.061
Loa Loa (eye worm) hypothetical protein 0.0122 0.0034 0.0029
Brugia malayi GnHR receptor homolog 0.0257 0.0371 0.0353
Loa Loa (eye worm) cysteine protease 0.1194 0.2707 0.2704
Plasmodium falciparum serine repeat antigen 4 0.0281 0.0432 0.1504
Brugia malayi protein unc-22 0.0183 0.0188 0.017
Plasmodium vivax casein kinase 1, putative 0.0318 0.0523 0.1845
Trichomonas vaginalis AGC family protein kinase 0.0425 0.079 0.2915
Echinococcus granulosus roundabout 2 0.0127 0.0048 0.0043
Loa Loa (eye worm) glutaminase 2 0.0274 0.0413 0.0408
Echinococcus multilocularis cathepsin L 0.066 0.1377 0.1373
Trichomonas vaginalis CAMK family protein kinase 0.0514 0.1012 0.3736
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0376 0.0668 0.0664
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Loa Loa (eye worm) AUR protein kinase 0.0425 0.079 0.0786
Loa Loa (eye worm) hypothetical protein 0.0124 0.004 0.0035
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0237 0.0322 0.1096
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0654 0.1361 0.1357
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Entamoeba histolytica protein kinase, putative 0.012 0.0029 0.0031
Brugia malayi Immunoglobulin I-set domain containing protein 0.0637 0.1318 0.1302
Schistosoma mansoni tyrosine kinase 0.0521 0.1029 0.1025
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0245 0.0342 0.1035
Plasmodium vivax protein kinase Crk2 0.0347 0.0597 0.2119
Echinococcus multilocularis tyrosine protein kinase HCK 0.0277 0.0422 0.0417
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Trichomonas vaginalis STE family protein kinase 0.0398 0.0722 0.2665
Schistosoma mansoni hypothetical protein 0.0257 0.0371 0.0366
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Trypanosoma cruzi casein kinase, putative 0.0318 0.0523 0.0895
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus granulosus tyrosine kinase 0.0378 0.0674 0.0669
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0281 0.0432 0.0427
Schistosoma mansoni serine/threonine protein kinase 0.0355 0.0615 0.061
Trichomonas vaginalis CMGC family protein kinase 0.0347 0.0597 0.22
Echinococcus multilocularis dual specificity 0.0357 0.0622 0.0617
Schistosoma mansoni opsin-like receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0257 0.0371 0.0366
Brugia malayi Protein kinase domain containing protein 0.0352 0.0609 0.0592
Loa Loa (eye worm) hypothetical protein 0.0281 0.0432 0.0427
Echinococcus granulosus activated cdc42 kinase 1 0.0267 0.0396 0.0391
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0425 0.079 0.2864
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0749 0.1598 0.1594
Loa Loa (eye worm) hypothetical protein 0.0406 0.0742 0.0737
Entamoeba histolytica cysteine proteinase, putative 0.066 0.1377 0.5049
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0223 0.0286 0.0281
Brugia malayi RhoGAP domain containing protein 0.0223 0.0286 0.0269
Echinococcus multilocularis rho associated protein kinase 0.0948 0.2093 0.2089
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0248 0.0349 0.1222
Loa Loa (eye worm) thyroid receptor interactor 0.0291 0.0457 0.0453
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Trypanosoma brucei rac serine-threonine kinase, putative 0.0858 0.1871 0.6084
Echinococcus granulosus neuropeptide Y receptor 0.0257 0.0371 0.0366
Plasmodium falciparum casein kinase 1 0.0318 0.0523 0.1845
Echinococcus granulosus alpha 1A adrenergic receptor 0.0257 0.0371 0.0366
Schistosoma mansoni amine GPCR 0.0257 0.0371 0.0366
Leishmania major hypothetical protein, conserved 0.036 0.0628 0.1977
Trypanosoma cruzi cruzipain precursor, putative 0.0379 0.0676 0.1172
Schistosoma mansoni biogenic amine receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Echinococcus granulosus cathepsin L cysteine protease 0.066 0.1377 0.1373
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0453 0.086 0.0856
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0252 0.0359 0.0354
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Echinococcus multilocularis carboxylesterase 5A 0.0138 0.0074 0.0069
Trichomonas vaginalis glutaminase, putative 0.0274 0.0413 0.1521
Schistosoma mansoni serine/threonine kinase 0.0477 0.0919 0.0915
Brugia malayi Melatonin receptor type 1A 0.0257 0.0371 0.0353
Brugia malayi hypothetical protein 0.0164 0.014 0.0122
Entamoeba histolytica protein kinase domain containing protein 0.0376 0.0668 0.241
Brugia malayi Protein kinase domain containing protein 0.0182 0.0184 0.0166
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0149 0.0103 0.0276
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0257 0.0371 0.0366
Entamoeba histolytica cysteine protease, putative 0.0281 0.0432 0.1531
Echinococcus multilocularis mitogen activated protein kinase 3 0.0245 0.0342 0.0337
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0241 0.0332 0.0327
Echinococcus multilocularis unc 13 (munc13) 0.0125 0.0043 0.0038
Trypanosoma cruzi polo-like protein kinase, putative 0.0788 0.1695 0.3019
Loa Loa (eye worm) hypothetical protein 0.0325 0.0541 0.0537
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0176 0.0169 0.0164
Echinococcus granulosus G protein coupled receptor 139 0.0257 0.0371 0.0366
Loa Loa (eye worm) neuropeptide F receptor 0.0257 0.0371 0.0366
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0282 0.0434 0.0429
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Loa Loa (eye worm) casein kinase 0.0408 0.0748 0.0744
Loa Loa (eye worm) TK/ALK protein kinase 0.0567 0.1144 0.114
Brugia malayi Tachykinin-like peptides receptor 99D 0.0257 0.0371 0.0353
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0635 0.1313 0.1298
Brugia malayi serine/threonine-protein kinase PAK 7 0.0677 0.1418 0.1403
Echinococcus multilocularis serine threonine protein kinase 0.0596 0.1216 0.1212
Loa Loa (eye worm) hypothetical protein 0.0404 0.0737 0.0733
Onchocerca volvulus 0.0257 0.0371 0.1311
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0387 0.0695 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Echinococcus granulosus cyclin dependent kinase 7 0.0172 0.016 0.0155
Onchocerca volvulus 0.0183 0.0188 0.0632
Schistosoma mansoni tyrosine kinase 0.0622 0.1281 0.1277
Brugia malayi Protein kinase domain containing protein 0.0334 0.0563 0.0545
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1194 0.2707 0.2704
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Plasmodium falciparum NIMA related kinase 4 0.0149 0.0103 0.0276
Entamoeba histolytica cell division protein kinase 2, putative 0.0355 0.0616 0.2215
Schistosoma mansoni tyrosine kinase 0.0197 0.0223 0.0218
Echinococcus granulosus serine/threonine protein kinase 0.0479 0.0926 0.0921
Schistosoma mansoni protein kinase 0.0293 0.0461 0.0456
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0103 0.0376
Trypanosoma cruzi cysteine peptidase, putative 0.066 0.1377 0.2443
Echinococcus granulosus Rac GTPase activating protein 1 0.0122 0.0034 0.0029
Brugia malayi Immunoglobulin I-set domain containing protein 0.0201 0.0233 0.0215
Echinococcus granulosus orexin receptor type 2 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0186 0.0195 0.019
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0225 0.0291 0.0287
Onchocerca volvulus 0.0257 0.0371 0.1311
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0127 0.0048 0.0043
Loa Loa (eye worm) hypothetical protein 0.0122 0.0034 0.0029
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0453 0.086 0.0856
Echinococcus granulosus Protein kinase C brain isozyme 0.0717 0.1519 0.1515
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0262 0.0383 0.1171
Trypanosoma cruzi major cysteine proteinase, putative 0.0421 0.0781 0.1363
Loa Loa (eye worm) hypothetical protein 0.026 0.0378 0.0374
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0257 0.0371 0.1311
Brugia malayi putative neuropeptide receptor NPR1 0.0257 0.0371 0.0353
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Onchocerca volvulus 0.022 0.028 0.0973
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Schistosoma mansoni protein kinase 0.1286 0.2937 0.2933
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0281 0.0432 0.0427
Echinococcus multilocularis serotonin receptor 0.0375 0.0665 0.0661
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0318 0.0523 0.0518
Leishmania major protein kinase, putative 0.0204 0.0239 0.0693
Echinococcus granulosus tyrosine protein kinase HCK 0.0277 0.0422 0.0417
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0125 0.0043 0.0038
Giardia lamblia Cathepsin B precursor 0.0485 0.0939 0.4375
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0262 0.0383 0.1171
Schistosoma mansoni serine/threonine protein kinase 0.0685 0.1439 0.1435
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0257 0.0371 0.0366
Plasmodium vivax protein kinase, putative 0.015 0.0105 0.0284
Giardia lamblia Kinase, STE STE20 0.0241 0.0332 0.1198
Schistosoma mansoni growth factor receptor-bound protein 0.0176 0.0169 0.0164
Echinococcus multilocularis neuropeptides capa receptor 0.0257 0.0371 0.0366
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0248 0.0349 0.1057
Echinococcus multilocularis tyrosine protein kinase Srms 0.0378 0.0674 0.0669
Toxoplasma gondii aurora kinase 0.0425 0.079 0.2842
Brugia malayi larval opioid receptor 0.0257 0.0371 0.0353
Schistosoma mansoni cell adhesion molecule 0.0127 0.0048 0.0043
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0172 0.016 0.0155
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0635 0.1313 0.1309
Onchocerca volvulus 0.0178 0.0175 0.0583
Loa Loa (eye worm) hypothetical protein 0.0325 0.0541 0.0537
Trichomonas vaginalis AGC family protein kinase 0.0292 0.0459 0.1691
Schistosoma mansoni serine/threonine protein kinase 0.0648 0.1347 0.1342
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0425 0.079 0.0786
Loa Loa (eye worm) hypothetical protein 0.0115 0.0018 0.0013
Brugia malayi Variant SH3 domain containing protein 0.0176 0.0169 0.0151
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0325 0.0541 0.0928
Echinococcus granulosus neuroglian 0.0215 0.0266 0.0261
Plasmodium falciparum serine/threonine protein kinase KIN 0.0262 0.0383 0.1323
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0281 0.0432 0.0427
Echinococcus granulosus neuroglian 0.0127 0.0048 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0717 0.1519 0.1515
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0223 0.0286 0.0281
Echinococcus granulosus tyrosine protein kinase Src42A 0.0453 0.086 0.0856
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0257 0.0371 0.0366
Entamoeba histolytica hypothetical protein 0.012 0.0029 0.0031
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0159 0.0128 0.0468
Brugia malayi Pleckstrin Homology Domain 0.0144 0.0089 0.0071
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0241 0.0332 0.1
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0357 0.0622 0.1957
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0245 0.0342 0.0568
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0353 0.061 0.2169
Trichomonas vaginalis CAMK family protein kinase 0.0788 0.1695 0.626
Schistosoma mansoni amine GPCR 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.069 0.1452 0.1447
Brugia malayi Papain family cysteine protease containing protein 0.0281 0.0432 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Echinococcus multilocularis protein kinase c iota type 0.0839 0.1824 0.182
Brugia malayi cathepsin Z-like cysteine proteinase 0.0485 0.0939 0.0923
Brugia malayi AKH receptor 0.0257 0.0371 0.0353
Echinococcus multilocularis twitchin 0.0147 0.0098 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Loa Loa (eye worm) AGC/PKA protein kinase 0.0292 0.0459 0.0454
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0317 0.0521 0.0516
Brugia malayi Immunoglobulin I-set domain containing protein 0.0127 0.0048 0.003
Plasmodium falciparum calcium-dependent protein kinase 2 0.0317 0.0521 0.1837
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0292 0.0459 0.0779
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0677 0.1418 0.1414
Echinococcus multilocularis death associated protein kinase 1 0.1686 0.3935 0.3932
Schistosoma mansoni tyrosine kinase 0.0889 0.1947 0.1943
Schistosoma mansoni biogenic amine receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0334 0.0563 0.2075
Brugia malayi Protein kinase domain containing protein 0.0586 0.1191 0.1175
Loa Loa (eye worm) hypothetical protein 0.0379 0.0676 0.0671
Giardia lamblia Kinase, CMGC GSK 0.0376 0.0668 0.2958
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3112 0.749 0.9119
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0127 0.0047 0.0042
Trichomonas vaginalis CMGC family protein kinase 0.0347 0.0597 0.22
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Onchocerca volvulus Tyrosine kinase homolog 0.1064 0.2384 0.8798
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.066 0.1377 0.5084
Echinococcus granulosus roundabout 2 0.0127 0.0048 0.0043
Brugia malayi serine/threonine-protein kinase plk-2 0.0788 0.1695 0.168
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0352 0.0609 0.0604
Echinococcus multilocularis tyrosine protein kinase 0.0572 0.1156 0.1152
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Brugia malayi P38 map kinase family protein 2 0.0587 0.1193 0.1177
Brugia malayi Protein kinase domain containing protein 0.0477 0.0919 0.0903
Brugia malayi Immunoglobulin I-set domain containing protein 0.1221 0.2775 0.2762
Schistosoma mansoni adenoreceptor 0.0257 0.0371 0.0366
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0285 0.0441 0.0436
Echinococcus multilocularis dual specificity 0.0303 0.0487 0.0482
Entamoeba histolytica protein kinase domain containing protein 0.0357 0.0622 0.2237
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0788 0.1695 0.1691
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0591 0.1203 0.1199
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0796 0.1716 0.1712
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0281 0.0432 0.0427
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0379 0.0676 0.0671
Giardia lamblia Cathepsin L precursor 0.0281 0.0432 0.1722
Entamoeba histolytica casein kinase 1, putative 0.0318 0.0523 0.187
Brugia malayi Protein kinase domain containing protein 0.0239 0.0326 0.0308
Giardia lamblia Kinase, STE STE20 0.0252 0.0359 0.1339
Loa Loa (eye worm) carboxylesterase 0.0138 0.0074 0.0069
Schistosoma mansoni opsin-like receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0023 0.0019
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0378 0.0674 0.0669
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0161 0.0131 0.0185
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0873 0.1907 0.1903
Giardia lamblia Cathepsin B precursor 0.0916 0.2014 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.066 0.1377 0.4452
Echinococcus granulosus insulin receptor 0.0889 0.1947 0.1943
Echinococcus multilocularis 0.0351 0.0606 0.0601
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0427 0.0795 0.0791
Echinococcus granulosus serine:threonine protein kinase 0.0334 0.0563 0.0558
Echinococcus granulosus cyclin dependent kinase 5 0.0347 0.0597 0.0592
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0292 0.0459 0.1605
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0398 0.0722 0.2589
Echinococcus granulosus cysteine protease 0.066 0.1377 0.1373
Schistosoma mansoni neuropeptide receptor 0.0257 0.0371 0.0366
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.066 0.1377 0.4452
Schistosoma mansoni serine/threonine protein kinase 0.0239 0.0326 0.0321
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Leishmania major protein kinase A catalytic subunit isoform 1 0.0292 0.0459 0.142
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0113 0.0413
Echinococcus granulosus casein kinase I alpha 0.0318 0.0523 0.0518
Leishmania major serine/threonine-protein kinase, putative 0.0149 0.0103 0.0244
Schistosoma mansoni serine/threonine protein kinase 0.1148 0.2594 0.259
Schistosoma mansoni tyrosine kinase 0.08 0.1725 0.1721
Brugia malayi Protein kinase domain containing protein 0.2742 0.6567 0.6561
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1194 0.2707 0.2704
Brugia malayi Cam kinase protein 1 0.0317 0.0521 0.0504
Trypanosoma cruzi cysteine protease, putative 0.066 0.1377 0.2443
Entamoeba histolytica protein kinase, putative 0.0376 0.0668 0.241
Loa Loa (eye worm) hypothetical protein 0.0379 0.0676 0.0671
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0257 0.0371 0.0366
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0044 0.0026
Echinococcus multilocularis protein tyrosine kinase 0.1091 0.245 0.2446
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0587 0.1194 0.119
Leishmania major cathepsin L-like protease 0.1194 0.2707 0.8846
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0591 0.1203 0.1199
Echinococcus multilocularis activated cdc42 kinase 1 0.0267 0.0396 0.0391
Entamoeba histolytica cysteine protease, putative 0.0281 0.0432 0.1531
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0281 0.0432 0.0427
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.036 0.0628 0.0623
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0292 0.0459 0.142
Chlamydia trachomatis replicative DNA helicase 0.0387 0.0695 1
Giardia lamblia Kinase, CAMK CAMKL 0.0269 0.0402 0.1568
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0485 0.0939 0.3466
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0449 0.0849 0.1486
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Schistosoma mansoni growth factor receptor-bound protein 0.0181 0.0183 0.0178
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0257 0.0371 0.0353
Echinococcus granulosus cathepsin l1 0.0815 0.1762 0.1758
Schistosoma mansoni hypothetical protein 0.036 0.0628 0.0623
Trichomonas vaginalis STE family protein kinase 0.0189 0.0201 0.074
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0127 0.0048 0.0043
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0721 0.1529 0.1525
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis neuropeptide receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0419 0.0775 0.286
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0252 0.0359 0.0354
Trypanosoma cruzi cysteine peptidase, putative 0.1334 0.3057 0.5486
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0873 0.1907 0.7022
Echinococcus multilocularis g protein coupled receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0164 0.014 0.0135
Echinococcus granulosus casein kinase I alpha 0.0318 0.0523 0.0518
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1194 0.2707 1
Echinococcus granulosus defective proboscis extension response 0.0165 0.0142 0.0138
Loa Loa (eye worm) hypothetical protein 0.0168 0.015 0.0145
Echinococcus granulosus serine:threonine protein kinase N2 0.0377 0.0671 0.0667
Brugia malayi Protein kinase domain containing protein 0.0347 0.0597 0.058
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0469 0.0901 0.0897
Onchocerca volvulus 0.1194 0.2707 1
Echinococcus multilocularis casein kinase I alpha 0.0318 0.0523 0.0518
Brugia malayi Papain family cysteine protease containing protein 0.0281 0.0432 0.0415
Entamoeba histolytica protein kinase domain containing protein 0.0425 0.079 0.2864
Brugia malayi Cathepsin L-like precursor 0.0815 0.1762 0.1747
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0342 0.126
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0257 0.0372 0.0367
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0449 0.0849 0.2709
Onchocerca volvulus Cathepsin L homolog 0.0281 0.0432 0.1539
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0317 0.0521 0.0516
Loa Loa (eye worm) hypothetical protein 0.0161 0.0131 0.0126
Echinococcus multilocularis acetylcholinesterase 0.0138 0.0074 0.0069
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0654 0.1361 0.1357
Trichomonas vaginalis STE family protein kinase 0.0252 0.0359 0.1321
Loa Loa (eye worm) hypothetical protein 0.0267 0.0396 0.0391
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0457 0.0871 0.0866
Brugia malayi Dopamine receptor protein 2 0.0257 0.0371 0.0353
Plasmodium falciparum calcium-dependent protein kinase 4 0.0317 0.0521 0.1837
Echinococcus multilocularis roundabout 2 0.0127 0.0048 0.0043
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0257 0.0371 0.0366
Loa Loa (eye worm) TK/ABL protein kinase 0.0411 0.0755 0.075
Loa Loa (eye worm) hypothetical protein 0.0122 0.0034 0.0029
Onchocerca volvulus 0.036 0.0628 0.2267
Echinococcus multilocularis cathepsin b 0.2333 0.5548 0.5546
Plasmodium falciparum calcium-dependent protein kinase 5 0.0317 0.0521 0.1837
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0239 0.0326 0.0321
Schistosoma mansoni cathepsin C 0.0281 0.0432 0.0427
Onchocerca volvulus 0.1194 0.2707 1
Trichomonas vaginalis STE family protein kinase 0.0252 0.0359 0.1321
Toxoplasma gondii kringle domain-containing protein 0.036 0.0628 0.2235
Plasmodium falciparum protein kinase, putative 0.0204 0.0239 0.0783
Brugia malayi SRC-1 0.0453 0.086 0.0843
Echinococcus multilocularis roundabout 2 0.0127 0.0048 0.0043
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0364 0.0639 0.2015
Echinococcus multilocularis PAK box P21 Rho binding 0.0189 0.0201 0.0197
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1069 0.2395 0.2391
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0257 0.0371 0.0353
Loa Loa (eye worm) hypothetical protein 0.0201 0.0233 0.0228
Schistosoma mansoni serine/threonine protein kinase 0.0295 0.0466 0.0461
Echinococcus multilocularis transfer RNA-Thr 0.0267 0.0396 0.0391
Echinococcus granulosus dual specificity 0.0303 0.0487 0.0482
Loa Loa (eye worm) hypothetical protein 0.0654 0.1361 0.1357
Trypanosoma brucei protein kinase, putative 0.0253 0.0361 0.1098
Echinococcus granulosus RNA directed DNA polymerase 0.0115 0.0018 0.0013
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0387 0.0695 1
Plasmodium falciparum serine repeat antigen 8 0.0281 0.0432 0.1504
Brugia malayi diacylglycerol kinase 0.0122 0.0034 0.0016
Echinococcus granulosus c-Jun N-terminal kinases 0.4119 1 1
Trypanosoma cruzi cysteine proteinase, putative 0.066 0.1377 0.2443
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0017 0.0012
Leishmania major protein kinase, putative 0.0449 0.0849 0.2709
Trypanosoma brucei polo-like protein kinase 0.0788 0.1695 0.5503
Entamoeba histolytica protein kinase, putative 0.0425 0.079 0.2864
Echinococcus multilocularis protein KINase family member (kin 25) 0.0168 0.015 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0916 0.2014 0.7439
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Echinococcus granulosus nervana 2 0.036 0.0628 0.0623
Echinococcus granulosus dro:myosuppressin receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) TK/ROR protein kinase 0.0516 0.1016 0.1012

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 2720 nM Inhibition of human factor 10a ChEMBL. 16982190
Ki (binding) = 2720 nM Inhibition of human factor 10a ChEMBL. 16982190

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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