Detailed information for compound 415135

Basic information

Technical information
  • TDR Targets ID: 415135
  • Name: (2S)-N-(2-aminoethyl)-2-[(3S)-3-[(6-chloronap hthalen-2-yl)sulfonylamino]-2-oxopyrrolidin-1 -yl]-N-propan-2-ylpropanamide
  • MW: 481.008 | Formula: C22H29ClN4O4S
  • H donors: 2 H acceptors: 4 LogP: 2.25 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCCN(C(=O)[C@@H](N1CC[C@@H](C1=O)NS(=O)(=O)c1ccc2c(c1)ccc(c2)Cl)C)C(C)C
  • InChi: 1S/C22H29ClN4O4S/c1-14(2)26(11-9-24)21(28)15(3)27-10-8-20(22(27)29)25-32(30,31)19-7-5-16-12-18(23)6-4-17(16)13-19/h4-7,12-15,20,25H,8-11,24H2,1-3H3/t15-,20-/m0/s1
  • InChiKey: FBHQNSBRZXDZSA-YWZLYKJASA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-N-(2-aminoethyl)-2-[(3S)-3-[(6-chloro-2-naphthyl)sulfonylamino]-2-oxo-pyrrolidin-1-yl]-N-isopropyl-propanamide
  • (2S)-N-(2-aminoethyl)-2-[(3S)-3-[(6-chloro-2-naphthyl)sulfonylamino]-2-oxo-1-pyrrolidinyl]-N-isopropylpropanamide
  • (2S)-N-(2-azanylethyl)-2-[(3S)-3-[(6-chloronaphthalen-2-yl)sulfonylamino]-2-oxo-pyrrolidin-1-yl]-N-propan-2-yl-propanamide
  • (2S)-N-(2-aminoethyl)-2-[(3S)-3-[(6-chloro-2-naphthyl)sulfonylamino]-2-keto-pyrrolidino]-N-isopropyl-propionamide
  • (2S)-N-(2-aminoethyl)-2-[(3S)-3-[(6-chloro-2-naphthyl)sulfonylamino]-2-keto-pyrrolidin-1-yl]-N-isopropyl-propionamide
  • (2S)-N-(2-aminoethyl)-2-[(3S)-3-[(6-chloronaphthalen-2-yl)sulfonylamino]-2-oxo-pyrrolidin-1-yl]-N-propan-2-yl-propanamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor X Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0303 0.0487 0.1514
Echinococcus granulosus serine:threonine protein kinase 3 0.0749 0.1598 0.1594
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0281 0.0432 0.1592
Echinococcus granulosus neuropeptide receptor A26 0.0257 0.0371 0.0366
Giardia lamblia Encystation-specific protease 0.0353 0.061 0.2653
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0262 0.0383 0.0642
Leishmania major cathepsin L-like protease 0.1194 0.2707 0.8846
Trichomonas vaginalis AGC family protein kinase 0.012 0.0029 0.0103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1307 0.2988 0.2985
Brugia malayi Papain family cysteine protease containing protein 0.1194 0.2707 0.2694
Echinococcus multilocularis tyrosine protein kinase Abl 0.036 0.0628 0.0623
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Schistosoma mansoni hypothetical protein 0.0257 0.0371 0.0366
Schistosoma mansoni protein kinase 0.0318 0.0523 0.0518
Echinococcus granulosus tyrosine protein kinase 0.0572 0.1156 0.1152
Loa Loa (eye worm) AUR protein kinase 0.0425 0.079 0.0786
Schistosoma mansoni protein kinase 0.0425 0.079 0.0786
Echinococcus granulosus tyrosine protein kinase shark 0.0622 0.1281 0.1277
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0721 0.1529 0.1525
Echinococcus multilocularis serine:threonine protein kinase 0.0334 0.0563 0.0558
Loa Loa (eye worm) TK protein kinase 0.0695 0.1464 0.146
Plasmodium falciparum serine repeat antigen 1 0.0281 0.0432 0.1504
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Brugia malayi C1-like domain containing protein 0.0635 0.1313 0.1298
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0103 0.0376
Brugia malayi Cathepsin L-like precursor 0.1194 0.2707 0.2694
Trypanosoma brucei NIMA-related protein kinase 0.0149 0.0103 0.0244
Brugia malayi Papain family cysteine protease containing protein 0.066 0.1377 0.1361
Onchocerca volvulus 0.0153 0.0113 0.0352
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0281 0.0432 0.1504
Schistosoma mansoni serine/threonine protein kinase 0.0744 0.1585 0.158
Schistosoma mansoni serine/threonine protein kinase 0.0355 0.0615 0.061
Echinococcus granulosus Immunoglobulin 0.0165 0.0142 0.0138
Loa Loa (eye worm) hypothetical protein 0.0537 0.107 0.1066
Brugia malayi cathepsin L-like precursor 0.0815 0.1762 0.1747
Onchocerca volvulus 0.1194 0.2707 1
Brugia malayi map kinase activated protein kinase protein 2 0.1148 0.2594 0.2581
Loa Loa (eye worm) RasGEF domain-containing protein 0.0122 0.0034 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0355 0.0615 0.061
Brugia malayi protein kinase C3,putative 0.046 0.0879 0.0862
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2333 0.5548 0.5546
Echinococcus multilocularis cyclin dependent kinase 7 0.0172 0.016 0.0155
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Brugia malayi diacylglycerol kinase 0.0122 0.0034 0.0016
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0281 0.0432 0.0427
Plasmodium vivax calcium-dependent protein kinase, putative 0.0317 0.0521 0.1837
Schistosoma mansoni protein kinase 0.0167 0.0147 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Onchocerca volvulus 0.0948 0.2093 0.7716
Plasmodium falciparum serine repeat antigen 9 0.0281 0.0432 0.1504
Entamoeba histolytica protein kinase, putative 0.0252 0.0359 0.1259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0815 0.1762 0.6508
Loa Loa (eye worm) hypothetical protein 0.0127 0.0048 0.0043
Toxoplasma gondii diacylglycerol kinase, putative 0.0122 0.0034 0.002
Giardia lamblia Kinase, CMGC SRPK 0.0243 0.0338 0.1229
Brugia malayi Protein kinase domain containing protein 0.0567 0.1145 0.1129
Loa Loa (eye worm) hypothetical protein 0.0257 0.0372 0.0367
Entamoeba histolytica protein kinase, putative 0.0243 0.0338 0.118
Schistosoma mansoni serine/threonine protein kinase 0.0788 0.1695 0.1691
Trichomonas vaginalis AGC family protein kinase 0.0239 0.0326 0.12
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Schistosoma mansoni nck2/grb4 0.0176 0.0169 0.0164
Loa Loa (eye worm) TK/FAK protein kinase 0.1102 0.2479 0.2476
Brugia malayi cell division control protein 2 homolog 0.0347 0.0597 0.058
Brugia malayi probable protein kinase 0.0772 0.1656 0.1641
Trichomonas vaginalis STE family protein kinase 0.0149 0.0103 0.0376
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Giardia lamblia Kinase, CMGC CK2 0.0293 0.0461 0.1874
Schistosoma mansoni cathepsin F (C01 family) 0.0815 0.1762 0.1758
Toxoplasma gondii AGC kinase 0.0292 0.0459 0.1605
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0248 0.0349 0.1222
Schistosoma mansoni serine/threonine protein kinase 0.4119 1 1
Giardia lamblia Kinase, NEK 0.0398 0.0722 0.3241
Echinococcus multilocularis RNA directed DNA polymerase 0.0115 0.0018 0.0013
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0656 0.1366 0.1362
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0376 0.0668 0.0664
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0137 0.0073 0.0265
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trypanosoma brucei Casein kinase II 0.0293 0.0461 0.1427
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0113 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0487 0.1796
Echinococcus granulosus dual specificity 0.0357 0.0622 0.0617
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Echinococcus granulosus tm gpcr rhodopsin 0.0257 0.0371 0.0366
Onchocerca volvulus 0.0257 0.0371 0.1311
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0262 0.0383 0.0379
Schistosoma mansoni tyrosine kinase 0.0168 0.015 0.0145
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Echinococcus granulosus casein kinase I delta 0.0318 0.0523 0.0518
Schistosoma mansoni neuroglian 0.0127 0.0048 0.0043
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Entamoeba histolytica cysteine proteinase, putative 0.0815 0.1762 0.6482
Entamoeba histolytica protein kinase, putative 0.0243 0.0338 0.118
Schistosoma mansoni protein kinase 0.1069 0.2395 0.2391
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0157 0.0122 0.0117
Brugia malayi G protein-coupled receptor F59B2.13 0.0257 0.0371 0.0353
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0257 0.0371 0.0366
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Onchocerca volvulus 0.0376 0.0668 0.2417
Treponema pallidum replicative DNA helicase (dnaB) 0.0387 0.0695 1
Entamoeba histolytica protein kinase, putative 0.0357 0.0622 0.2237
Schistosoma mansoni diacylglycerol kinase theta 0.0122 0.0034 0.0029
Plasmodium falciparum protein serine/threonine kinase-1 0.0449 0.0849 0.3063
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0113 0.0413
Plasmodium falciparum casein kinase 2, alpha subunit 0.0293 0.0461 0.1613
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0591 0.1203 0.1199
Loa Loa (eye worm) hypothetical protein 0.0281 0.0432 0.0427
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0257 0.0371 0.0366
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0449 0.0849 0.1486
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.066 0.1377 0.2443
Giardia lamblia Cysteine protease 0.0281 0.0432 0.1722
Entamoeba histolytica PH domain containing protein kinase, putative 0.0314 0.0514 0.1836
Echinococcus multilocularis epidermal growth factor receptor 0.08 0.1725 0.1721
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0587 0.1193 0.211
Schistosoma mansoni diacylglycerol kinase theta 0.0122 0.0034 0.0029
Brugia malayi Protein kinase domain containing protein 0.0889 0.1947 0.1932
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0199 0.0226 0.0765
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0292 0.0459 0.0779
Echinococcus multilocularis calcium dependent protein kinase 0.0219 0.0278 0.0273
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0916 0.2014 0.3597
Echinococcus multilocularis neuroglian 0.0127 0.0048 0.0043
Brugia malayi Fibronectin type III domain containing protein 0.0201 0.0233 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0383 0.0379
Onchocerca volvulus 0.0257 0.0371 0.1311
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0292 0.0459 0.0441
Brugia malayi serine/threonine-protein kinase 6 0.0425 0.079 0.0773
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0477 0.0919 0.0915
Onchocerca volvulus Serine\/threonine kinase homolog 0.0788 0.1695 0.6236
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.016 0.0155
Brugia malayi SH2 domain containing protein 0.0796 0.1716 0.1701
Entamoeba histolytica protein kinase domain containing protein 0.0204 0.0239 0.0812
Echinococcus granulosus biogenic amine 5HT receptor 0.0257 0.0371 0.0366
Onchocerca volvulus 0.0318 0.0523 0.1877
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0295 0.0466 0.0461
Loa Loa (eye worm) hypothetical protein 0.0466 0.0892 0.0887
Giardia lamblia Kinase, CDC7 0.0153 0.0113 0.0053
Brugia malayi Protein kinase domain containing protein 0.0207 0.0248 0.023
Trichomonas vaginalis CMGC family protein kinase 0.0347 0.0597 0.22
Leishmania major cathepsin L-like protease 0.1334 0.3057 1
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Schistosoma mansoni serine/threonine protein kinase 0.0449 0.0849 0.0845
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Brugia malayi Ras association domain family 1 isoform A 0.0122 0.0034 0.0016
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Onchocerca volvulus 0.0993 0.2205 0.8134
Schistosoma mansoni hypothetical protein 0.0257 0.0372 0.0367
Echinococcus granulosus aurora kinase A 0.0425 0.079 0.0786
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0115 0.0018 0.0013
Echinococcus granulosus neuropeptide receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis fmrfamide receptor 0.0257 0.0371 0.0366
Echinococcus granulosus cyclin dependent kinase 9 0.0149 0.0102 0.0097
Schistosoma mansoni protein kinase 0.0204 0.0239 0.0234
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Entamoeba histolytica protein kinase 2, putative 0.0457 0.0871 0.3165
Onchocerca volvulus 0.0257 0.0371 0.1311
Loa Loa (eye worm) fibroinase 0.1194 0.2707 0.2704
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0673 0.1408 0.1404
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Echinococcus granulosus contactin 0.0127 0.0048 0.0043
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0257 0.0371 0.0366
Brugia malayi hypothetical protein 0.0648 0.1347 0.1331
Trichomonas vaginalis CAMK family protein kinase 0.0796 0.1714 0.633
Loa Loa (eye worm) hypothetical protein 0.0815 0.1762 0.1758
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0127 0.0048 0.0043
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0376 0.0668 0.0664
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Echinococcus granulosus activin receptor type 0.0558 0.1123 0.1118
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2742 0.6567 0.6565
Echinococcus granulosus rho-associated protein kinase 1 0.0948 0.2093 0.2089
Trypanosoma cruzi cysteine peptidase, putative 0.0379 0.0676 0.1172
Schistosoma mansoni unc-13 (munc13) 0.0125 0.0043 0.0038
Trypanosoma cruzi major cysteine proteinase, putative 0.0281 0.0432 0.073
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0194 0.0216 0.0211
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0204 0.0239 0.038
Echinococcus granulosus cGMP dependent protein kinase 0.0295 0.0466 0.0461
Schistosoma mansoni protein kinase 0.0656 0.1366 0.1362
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Trichomonas vaginalis CAMK family protein kinase 0.0369 0.0652 0.2403
Echinococcus multilocularis casein kinase I alpha 0.0318 0.0523 0.0518
Brugia malayi Cathepsin L-like precursor 0.0379 0.0676 0.0659
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0673 0.1408 0.1404
Brugia malayi protein kinase C II. 0.0602 0.1232 0.1216
Schistosoma mansoni cathepsin F (C01 family) 0.1194 0.2707 0.2704
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0376 0.0668 0.0664
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0425 0.079 0.2864
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0542 0.1082 0.1078
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0378 0.0674 0.0669
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0204 0.0239 0.038
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0149 0.0103 0.0244
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0208 0.0249 0.0244
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0485 0.0939 0.3466
Trichomonas vaginalis AGC family protein kinase 0.0425 0.079 0.2915
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0383 0.0379
Echinococcus multilocularis expressed protein 0.0243 0.0338 0.0333
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0342 0.126
Echinococcus granulosus hypothetical protein 0.0351 0.0606 0.0601
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0453 0.086 0.0856
Brugia malayi Protein kinase domain containing protein 0.0207 0.0248 0.023
Echinococcus multilocularis neuroglian 0.0215 0.0266 0.0261
Entamoeba histolytica protein kinase, putative 0.012 0.0029 0.0031
Leishmania major cathepsin L-like protease 0.1194 0.2707 0.8846
Brugia malayi Serotonin receptor 0.0257 0.0371 0.0353
Echinococcus multilocularis dual specificity 0.0303 0.0487 0.0482
Brugia malayi Protein kinase domain containing protein 0.0514 0.1012 0.0996
Brugia malayi Protein kinase domain containing protein 0.0466 0.0892 0.0876
Schistosoma mansoni protein kinase 0.0252 0.0359 0.0354
Schistosoma mansoni rap gtpase-activating protein 0.0325 0.0541 0.0537
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0113 0.0413
Trichomonas vaginalis AGC family protein kinase 0.0484 0.0938 0.3463
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0206 0.0246 0.0241
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0648 0.1347 0.1342
Echinococcus multilocularis netrin receptor unc 5 0.0126 0.0044 0.0039
Loa Loa (eye worm) hypothetical protein 0.0334 0.0563 0.0558
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0245 0.0342 0.117
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0127 0.0048 0.0043
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Loa Loa (eye worm) AUR protein kinase 0.0425 0.079 0.0786
Schistosoma mansoni titin 0.0183 0.0188 0.0183
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Schistosoma mansoni serine/threonine protein kinase 0.0591 0.1203 0.1199
Loa Loa (eye worm) hypothetical protein 0.0404 0.0737 0.0733
Schistosoma mansoni protein kinase 0.0656 0.1366 0.1362
Onchocerca volvulus 0.0416 0.0767 0.2784
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0223 0.0286 0.0281
Entamoeba histolytica cysteine proteinase 2 0.066 0.1377 0.5049
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0457 0.0871 0.3144
Brugia malayi Immunoglobulin I-set domain containing protein 0.0127 0.0048 0.003
Echinococcus granulosus tyrosine protein kinase Src64B 0.0453 0.086 0.0856
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0357 0.0622 0.1074
Echinococcus granulosus netrin receptor unc 5 0.0126 0.0044 0.0039
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0487 0.1796
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.08 0.1725 0.1721
Brugia malayi Protein kinase domain containing protein 0.0153 0.0113 0.0095
Loa Loa (eye worm) cathepsin B 0.0916 0.2014 0.201
Brugia malayi Protein kinase domain containing protein 0.0207 0.0248 0.023
Brugia malayi ephrin receptor 1 precursor 0.0194 0.0214 0.0197
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0317 0.0521 0.0516
Echinococcus granulosus TGF-beta receptor type-1 0.0167 0.0147 0.0142
Schistosoma mansoni protein kinase C mu 0.0635 0.1313 0.1309
Echinococcus multilocularis nervana 2 0.036 0.0628 0.0623
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0295 0.0466 0.1632
Brugia malayi hypothetical protein 0.0325 0.0541 0.0524
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.012 0.0029 0.0103
Loa Loa (eye worm) hypothetical protein 0.0144 0.0089 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.0459 0.0454
Brugia malayi Carboxylesterase family protein 0.0138 0.0074 0.0056
Entamoeba histolytica protein kinase domain containing protein 0.0427 0.0795 0.2884
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0469 0.0901 0.4176
Entamoeba histolytica protein kinase, putative 0.0425 0.079 0.2864
Schistosoma mansoni serine/threonine protein kinase 0.0208 0.0249 0.0244
Loa Loa (eye worm) hypothetical protein 0.0256 0.0369 0.0365
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0387 0.0695 0.27
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0281 0.0432 0.1531
Echinococcus multilocularis protein kinase c eta type 0.0122 0.0034 0.0029
Plasmodium falciparum NIMA related kinase 1 0.0398 0.0722 0.2589
Entamoeba histolytica protein kinase domain containing protein 0.0376 0.0668 0.241
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0425 0.079 0.2842
Echinococcus multilocularis cathepsin b 0.2333 0.5548 0.5546
Giardia lamblia Cathepsin B precursor 0.0281 0.0432 0.1722
Onchocerca volvulus 0.0257 0.0371 0.1311
Echinococcus granulosus 7tm_1 domain containing protein 0.0257 0.0371 0.0366
Schistosoma mansoni amine GPCR 0.0257 0.0371 0.0366
Schistosoma mansoni hypothetical protein 0.0257 0.0372 0.0367
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.016 0.0155
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.066 0.1377 0.1373
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0176 0.0169 0.0164
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0586 0.1191 0.1186
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0318 0.0523 0.0518
Giardia lamblia Cathepsin L precursor 0.0281 0.0432 0.1722
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0208 0.0249 0.0244
Leishmania major protein kinase, putative 0.0317 0.0521 0.1625
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.4119 1 1
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0317 0.0521 0.1837
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0165 0.0142 0.0138
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0317 0.0521 0.0516
Trichomonas vaginalis AGC family protein kinase 0.0516 0.1018 0.3758
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.0597 0.0592
Schistosoma mansoni vam6/vps39 related 0.0325 0.0541 0.0537
Loa Loa (eye worm) hypothetical protein 0.0154 0.0116 0.0111
Echinococcus granulosus growth factor receptor bound protein 2 0.0181 0.0183 0.0178
Entamoeba histolytica serine/threonine protein kinase, putative 0.0149 0.0103 0.0306
Entamoeba histolytica casein kinase, putative 0.0318 0.0523 0.187
Loa Loa (eye worm) hypothetical protein 0.0815 0.1762 0.1758
Echinococcus granulosus tyrosine protein kinase Blk 0.0378 0.0674 0.0669
Giardia lamblia Kinase, CAMK CAMKL 0.0269 0.0402 0.1568
Brugia malayi RhoGEF domain containing protein 0.0122 0.0034 0.0016
Brugia malayi Protein kinase domain containing protein 0.1069 0.2395 0.2381
Brugia malayi Protein kinase domain containing protein 0.0858 0.1871 0.1856
Entamoeba histolytica protein kinase, putative 0.0277 0.0422 0.1494
Brugia malayi Protein kinase domain containing protein 0.0207 0.0248 0.023
Echinococcus granulosus mitogen activated protein kinase 3 0.0245 0.0342 0.0337
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0299 0.0294
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0318 0.0523 0.0518
Loa Loa (eye worm) raf kinase 0.0122 0.0034 0.0029
Loa Loa (eye worm) AGC/PKG protein kinase 0.0295 0.0466 0.0461
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0376 0.0668 0.1158
Schistosoma mansoni serine/threonine-protein kinase 0.0479 0.0926 0.0921
Giardia lamblia Cathepsin L precursor 0.0281 0.0432 0.1722
Brugia malayi Kringle domain containing protein 0.036 0.0628 0.0611
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0398 0.0723 0.2667
Trypanosoma cruzi cdc2-related kinase 1 0.0347 0.0597 0.1029
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0103 0.0376
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0183 0.0188 0.0183
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0398 0.0722 0.2589
Schistosoma mansoni protein kinase C 0.0125 0.0043 0.0038
Plasmodium vivax serine-repeat antigen (SERA) 0.0281 0.0432 0.1504
Schistosoma mansoni nephrin 0.0127 0.0048 0.0043
Entamoeba histolytica protein kinase, putative 0.0208 0.0249 0.0849
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0925 0.2037 0.2033
Giardia lamblia Kinase, AGC PKA 0.0457 0.0871 0.4019
Loa Loa (eye worm) hypothetical protein 0.036 0.0628 0.0623
Echinococcus granulosus acetylcholinesterase 0.0138 0.0074 0.0069
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0257 0.0371 0.0366
Echinococcus granulosus tyrosine protein kinase Fyn 0.0453 0.086 0.0856
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0969 0.2147 0.2132
Echinococcus multilocularis cathepsin L cysteine protease 0.1194 0.2707 0.2704
Trypanosoma cruzi hypothetical protein, conserved 0.036 0.0628 0.1085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.066 0.1377 0.5084
Onchocerca volvulus 0.0257 0.0371 0.1311
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Schistosoma mansoni protein kinase 0.1286 0.2937 0.2933
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0427 0.0795 0.0791
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0453 0.086 0.0856
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0325 0.0541 0.0537
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0873 0.1907 0.1903
Schistosoma mansoni hypothetical protein 0.0325 0.0541 0.0537
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0457 0.0871 0.1526
Brugia malayi Protein kinase domain containing protein 0.1102 0.2479 0.2466
Echinococcus multilocularis g protein coupled receptor 0.0257 0.0371 0.0366
Brugia malayi Protein kinase domain containing protein 0.0267 0.0396 0.0379
Giardia lamblia Kinase, CMGC CDK 0.0347 0.0597 0.2583
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0246 0.0345 0.034
Echinococcus granulosus NDR protein kinase 0.0477 0.0919 0.0915
Onchocerca volvulus 0.1194 0.2707 1
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0351 0.0606 0.0601
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0257 0.0371 0.0366
Echinococcus granulosus peptide allatostatin:somatostatin 0.0257 0.0371 0.0366
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0469 0.0901 0.3256
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0317 0.0521 0.1837
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0587 0.1193 0.211
Echinococcus multilocularis activin receptor type 0.0558 0.1123 0.1118
Schistosoma mansoni tyrosine kinase 0.0453 0.086 0.0856
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0513 0.101 0.1005
Plasmodium falciparum serine repeat antigen 5 0.0281 0.0432 0.1504
Entamoeba histolytica hypothetical protein 0.0738 0.1571 0.577
Echinococcus multilocularis geminin 0.017 0.0154 0.0149
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0993 0.2206 0.2203
Schistosoma mansoni protein kinase 0.0189 0.0201 0.0197
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trichomonas vaginalis STE family protein kinase 0.0252 0.0359 0.1321
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0925 0.2037 0.2033
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0281 0.0432 0.1504
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0427 0.0795 0.0791
Echinococcus granulosus dual specificity 0.0303 0.0487 0.0482
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0542 0.1082 0.1078
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0127 0.0048 0.0043
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0303 0.0487 0.047
Schistosoma mansoni ste20-related kinase 0.0598 0.1223 0.1218
Brugia malayi Protein kinase domain containing protein 0.0654 0.1361 0.1345
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis casein kinase I delta 0.0318 0.0523 0.0518
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0257 0.0371 0.0366
Brugia malayi casein kinase 1, delta 0.0318 0.0523 0.0506
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0648 0.1347 0.1342
Echinococcus multilocularis casein kinase i 0.0318 0.0523 0.0518
Brugia malayi SH2 domain containing protein 0.0207 0.0248 0.023
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Brugia malayi Dopamine receptor 0.0257 0.0371 0.0353
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Echinococcus granulosus tyrosine kinase 0.0207 0.0248 0.0243
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0485 0.0939 0.0935
Onchocerca volvulus Cathepsin L homolog 0.1194 0.2707 1
Schistosoma mansoni hypothetical protein 0.017 0.0154 0.0149
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0788 0.1695 0.1691
Loa Loa (eye worm) hypothetical protein 0.0416 0.0767 0.0762
Trypanosoma cruzi cysteine peptidase, putative 0.1334 0.3057 0.5486
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1194 0.2707 0.2704
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Echinococcus granulosus casein kinase I delta 0.0318 0.0523 0.0518
Brugia malayi Serotonin receptor 0.0257 0.0371 0.0353
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0969 0.2147 0.2143
Toxoplasma gondii CMGC kinase, CK2 family 0.0293 0.0461 0.1613
Brugia malayi Egg laying defective protein 4 0.0295 0.0466 0.0449
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0245 0.0342 0.0568
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0224 0.029 0.0285
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0427 0.0795 0.0779
Loa Loa (eye worm) hypothetical protein 0.0123 0.0038 0.0033
Brugia malayi Protein kinase domain containing protein 0.0243 0.0338 0.032
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0379 0.0676 0.0659
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0353 0.061 0.2169
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0292 0.0459 0.0779
Loa Loa (eye worm) hypothetical protein 0.0206 0.0246 0.0241
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0103 0.0376
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0209 0.0253 0.0248
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0127 0.0048 0.0043
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0449 0.0849 0.1486
Brugia malayi cyclin-dependent kinase 7 homolog 0.018 0.0179 0.0161
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0453 0.086 0.0856
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0281 0.0432 0.1592
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0485 0.0939 0.3466
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0209 0.0253 0.0248
Echinococcus granulosus tissue type plasminogen activator 0.036 0.0628 0.0623
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Echinococcus multilocularis Immunoglobulin 0.0165 0.0142 0.0138
Schistosoma mansoni serine/threonine protein kinase 0.0477 0.0919 0.0915
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0591 0.1203 0.1199
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0281 0.0432 0.1592
Brugia malayi cathepsin L precursor 0.0281 0.0432 0.0415
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0257 0.0371 0.0366
Schistosoma mansoni protein kinase 0.0772 0.1656 0.1652
Echinococcus granulosus carboxylesterase 5A 0.0138 0.0074 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0721 0.1529 0.1525
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Schistosoma mansoni ephrin receptor 0.0292 0.046 0.0455
Schistosoma mansoni biogenic amine (5HT) receptor 0.0375 0.0665 0.0661
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.0487 0.1737
Trypanosoma cruzi p21-activated kinase 3, putative 0.0161 0.0131 0.0185
Echinococcus multilocularis G protein coupled receptor 139 0.0257 0.0371 0.0366
Brugia malayi cathepsin F-like cysteine proteinase 0.0281 0.0432 0.0415
Echinococcus granulosus cGMP dependent protein kinase 1 0.0295 0.0466 0.0461
Plasmodium falciparum protein kinase 5 0.0347 0.0597 0.2119
Echinococcus granulosus g-protein coupled receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Trypanosoma cruzi casein kinase, putative 0.0318 0.0523 0.0895
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0222 0.0284 0.0266
Trichomonas vaginalis STE family protein kinase 0.0252 0.0359 0.1321
Schistosoma mansoni tyrosine kinase 0.1205 0.2734 0.2731
Schistosoma mansoni Replicative DNA helicase 0.0387 0.0695 0.069
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Brugia malayi glutaminase DH11.1 0.0274 0.0413 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0281 0.0432 0.1504
Schistosoma mansoni tyrosine kinase 0.0694 0.1461 0.1456
Schistosoma mansoni kinase 0.0842 0.1829 0.1825
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Loa Loa (eye worm) hypothetical protein 0.0279 0.0427 0.0422
Loa Loa (eye worm) hypothetical protein 0.0138 0.0074 0.0069
Entamoeba histolytica cysteine protease, putative 0.0281 0.0432 0.1531
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0281 0.0432 0.1592
Echinococcus granulosus mitogen activated protein kinase 0.0245 0.0342 0.0337
Trypanosoma cruzi cdc2-related kinase 3 0.0347 0.0597 0.1029
Echinococcus multilocularis c src tyrosine kinase 0.0282 0.0434 0.0429
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Echinococcus granulosus epidermal growth factor receptor 0.08 0.1725 0.1721
Plasmodium falciparum calcium-dependent protein kinase 3 0.0317 0.0521 0.1837
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis protein kinase c epsilon type 0.0602 0.1232 0.1227
Brugia malayi G-protein coupled receptor 0.0257 0.0371 0.0353
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0325 0.0541 0.1692
Brugia malayi Cathepsin L-like cysteine proteinase 0.0815 0.1762 0.1747
Brugia malayi cathepsin L-like cysteine proteinase 0.0281 0.0432 0.0415
Schistosoma mansoni glutaminase 0.0274 0.0413 0.0408
Entamoeba histolytica protein kinase, putative 0.0477 0.0919 0.3344
Giardia lamblia Hypothetical protein 0.0281 0.0432 0.1722
Echinococcus granulosus cathepsin L 0.066 0.1377 0.1373
Plasmodium falciparum serine repeat antigen 2 0.0281 0.0432 0.1504
Echinococcus granulosus dual specificity 0.0303 0.0487 0.0482
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Echinococcus multilocularis insulin receptor 0.0889 0.1947 0.1943
Brugia malayi Tyrosine-protein kinase abl-1 0.036 0.0628 0.0611
Onchocerca volvulus 0.0257 0.0371 0.1311
Echinococcus granulosus protein kinase 0.0447 0.0846 0.0841
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Entamoeba histolytica hypothetical protein 0.0281 0.0432 0.1531
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0278 0.0423 0.0418
Giardia lamblia Kinase, PLK 0.0788 0.1695 0.8331
Echinococcus granulosus tachykinin peptides receptor 99D 0.0257 0.0371 0.0366
Loa Loa (eye worm) TK protein kinase 0.0572 0.1156 0.1152
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0347 0.0597 0.1875
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Schistosoma mansoni myosin xvIII 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.088 0.1926 0.1922
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0675 0.1413 0.1409
Echinococcus granulosus c src tyrosine kinase 0.0282 0.0434 0.0429
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0281 0.0432 0.1592
Giardia lamblia Cathepsin L-like protease 0.0281 0.0432 0.1722
Schistosoma mansoni alpha-1 adrenergic receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Echinococcus granulosus titin 0.0183 0.0188 0.0183
Schistosoma mansoni tyrosine kinase 0.0453 0.086 0.0856
Brugia malayi Protein kinase domain containing protein 0.0654 0.1361 0.1345
Echinococcus granulosus cathepsin L 0.0281 0.0432 0.0427
Plasmodium falciparum serine repeat antigen 7 0.0281 0.0432 0.1504
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0248 0.0349 0.058
Schistosoma mansoni neuropeptide receptor 0.0257 0.0371 0.0366
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1069 0.2395 0.2391
Trichomonas vaginalis AGC family protein kinase 0.0538 0.1073 0.3961
Brugia malayi Immunoglobulin I-set domain containing protein 0.0127 0.0048 0.003
Brugia malayi Sex muscle abnormal protein 5 0.0176 0.0169 0.0151
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Echinococcus multilocularis G-protein coupled receptor, putative 0.0257 0.0371 0.0366
Trypanosoma brucei SNF1-related protein kinases, putative 0.0262 0.0383 0.1171
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0098 0.0093
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0257 0.0371 0.0366
Echinococcus multilocularis mitogen activated protein kinase 14 0.0587 0.1193 0.1189
Echinococcus granulosus serine threonine protein kinase nrc 0.0457 0.0871 0.0866
Echinococcus granulosus tyrosine protein kinase Src42A 0.0278 0.0423 0.0418
Trichomonas vaginalis AGC family protein kinase 0.0239 0.0326 0.12
Loa Loa (eye worm) acetylcholinesterase 1 0.0138 0.0074 0.0069
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0222 0.0284 0.0279
Loa Loa (eye worm) melatonin receptor type 1A 0.0257 0.0371 0.0366
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0453 0.086 0.0856
Schistosoma mansoni neuropeptide F-like receptor 0.0257 0.0371 0.0366
Schistosoma mansoni cell adhesion molecule 0.0243 0.0336 0.0331
Plasmodium falciparum cGMP-dependent protein kinase 0.0295 0.0466 0.1632
Giardia lamblia Kinase, CK1 Casein kinase 0.0318 0.0523 0.2198
Plasmodium vivax vivapain-2 0.1194 0.2707 1
Onchocerca volvulus 0.0404 0.0737 0.2675
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Loa Loa (eye worm) G-protein coupled receptor 0.0257 0.0371 0.0366
Entamoeba histolytica cysteine proteinase, putative 0.1194 0.2707 1
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0204 0.0239 0.0693
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0303 0.0487 0.1711
Brugia malayi Protein kinase domain containing protein 0.0207 0.0248 0.023
Schistosoma mansoni serine/threonine protein kinase 0.0586 0.1191 0.1187
Onchocerca volvulus 0.0207 0.0248 0.0853
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0317 0.0521 0.0516
Echinococcus multilocularis dual specificity 0.0303 0.0487 0.0482
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0317 0.0521 0.0504
Trichomonas vaginalis CK1 family protein kinase 0.0318 0.0523 0.1928
Onchocerca volvulus 0.0257 0.0371 0.1311
Loa Loa (eye worm) hypothetical protein 0.0281 0.0432 0.0427
Loa Loa (eye worm) TK/INSR protein kinase 0.0889 0.1947 0.1943
Echinococcus granulosus Glutaredoxin protein 5 0.036 0.0628 0.0623
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0252 0.0359 0.0354
Entamoeba histolytica cysteine proteinase, putative 0.066 0.1377 0.5049
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0243 0.0338 0.1153
Schistosoma mansoni serine/threonine protein kinase 0.0854 0.186 0.1856
Entamoeba histolytica protein kinase, putative 0.0189 0.0201 0.0673
Schistosoma mansoni amine GPCR 0.0257 0.0371 0.0366
Schistosoma mansoni protein kinase C mu 0.0122 0.0034 0.0029
Echinococcus granulosus cathepsin L cysteine proteinase 0.1194 0.2707 0.2704
Echinococcus multilocularis epidermal growth factor receptor 0.1205 0.2734 0.2731
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Toxoplasma gondii AGC kinase 0.0292 0.0459 0.1605
Echinococcus granulosus hypothetical protein 0.0257 0.0371 0.0366
Giardia lamblia Cathepsin L precursor 0.0281 0.0432 0.1722
Entamoeba histolytica protein kinase, putative 0.0199 0.0226 0.0765
Brugia malayi cathepsin F-like cysteine proteinase 0.0379 0.0676 0.0659
Echinococcus multilocularis acetylcholinesterase 0.0138 0.0074 0.0069
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0293 0.0461 0.1613
Onchocerca volvulus 0.0537 0.107 0.3912
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0357 0.0622 0.1074
Echinococcus granulosus raf serine:threonine protein kinase 0.0228 0.0299 0.0294
Echinococcus multilocularis neuropeptide FF receptor 2 0.0257 0.0371 0.0366
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0449 0.0849 0.2709
Echinococcus granulosus titin 0.0183 0.0188 0.0183
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1148 0.2594 0.259
Echinococcus granulosus acetylcholinesterase 0.0138 0.0074 0.0069
Onchocerca volvulus 0.0257 0.0371 0.1311
Echinococcus multilocularis 0.0338 0.0573 0.0568
Plasmodium vivax unspecified product 0.0379 0.0676 0.2416
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0257 0.0371 0.0366
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Brugia malayi Cathepsin L-like precursor 0.1194 0.2707 0.2694
Echinococcus granulosus protein kinase shaggy 0.0376 0.0668 0.0664
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Plasmodium vivax vivapain-1 0.066 0.1377 0.5033
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0257 0.0371 0.0366
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0796 0.1716 0.1712
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0156 0.0119 0.0114
Entamoeba histolytica p21-activated kinase 0.0274 0.0414 0.1463
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0156 0.0119 0.0114
Trichomonas vaginalis CMGC family protein kinase 0.0376 0.0668 0.2465
Entamoeba histolytica cysteine proteinase, putative 0.1194 0.2707 1
Echinococcus granulosus dual specificity protein kinase clk2 0.0449 0.0849 0.0845
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0149 0.0103 0.0244
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0131 0.0126
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0157 0.0122 0.0117
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0127 0.0048 0.0043
Giardia lamblia Kinase, AGC AKT 0.0342 0.0584 0.2518
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0269 0.0402 0.1394
Entamoeba histolytica cysteine protease, putative 0.1194 0.2707 1
Schistosoma mansoni hypothetical protein 0.0257 0.0371 0.0366
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.1286 0.2937 0.2933
Giardia lamblia Cathepsin B precursor 0.0916 0.2014 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Leishmania major cathepsin L-like protease 0.1194 0.2707 0.8846
Onchocerca volvulus 0.085 0.185 0.6812
Onchocerca volvulus 0.0153 0.0113 0.0352
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Echinococcus multilocularis g protein coupled receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0165 0.0142 0.0138
Loa Loa (eye worm) hypothetical protein 0.0675 0.1413 0.1409
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0281 0.0432 0.1504
Brugia malayi Protein kinase domain containing protein 0.0449 0.0849 0.0833
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2333 0.5548 1
Echinococcus multilocularis casein kinase I gamma 0.0506 0.0992 0.0987
Echinococcus granulosus g protein coupled receptor 0.0257 0.0371 0.0366
Schistosoma mansoni protein kinase 0.0252 0.0359 0.0354
Brugia malayi Variant SH3 domain containing protein 0.0127 0.0047 0.0029
Echinococcus granulosus tyrosine protein kinase Lyn 0.055 0.1103 0.1099
Leishmania major protein kinase, putative 0.0449 0.0849 0.2709
Leishmania major cysteine peptidase A (CPA) 0.1194 0.2707 0.8846
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus granulosus protein kinase c iota type 0.0839 0.1824 0.182
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0257 0.0371 0.0366
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis somatostatin receptor 0.0257 0.0371 0.0366
Trypanosoma cruzi casein kinase II, putative 0.0293 0.0461 0.0783
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0487 0.1796
Leishmania major protein kinase A catalytic subunit isoform 2 0.0292 0.0459 0.142
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0257 0.0371 0.0366
Echinococcus granulosus allatostatin A receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0166 0.0144 0.0139
Schistosoma mansoni serine/threonine protein kinase 0.096 0.2123 0.212
Plasmodium falciparum serine/threonine protein kinase, putative 0.0425 0.079 0.2842
Echinococcus multilocularis neuropeptide Y receptor 0.0257 0.0371 0.0366
Plasmodium falciparum cysteine proteinase falcipain 3 0.1194 0.2707 1
Loa Loa (eye worm) G-protein coupled receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) STE/STE11/MEKK2 protein kinase 0.0115 0.0018 0.0013
Echinococcus granulosus CDC7 cell division cycle 7 0.0153 0.0113 0.0108
Trypanosoma brucei aurora B kinase 0.0425 0.079 0.2514
Loa Loa (eye worm) hypothetical protein 0.0165 0.0142 0.0138
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1148 0.2594 0.259
Echinococcus granulosus fmrfamide receptor 0.0257 0.0371 0.0366
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0281 0.0432 0.1722
Schistosoma mansoni serine/threonine protein kinase 0.0685 0.1439 0.1435
Schistosoma mansoni serine/threonine protein kinase 0.0272 0.0409 0.0404
Brugia malayi Temporarily assigned gene name protein 59 0.0325 0.0541 0.0524
Brugia malayi Fes/CIP4 homology domain containing protein 0.0291 0.0457 0.044
Onchocerca volvulus 0.0908 0.1996 0.7353
Loa Loa (eye worm) hypothetical protein 0.0201 0.0233 0.0228
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0376 0.0668 0.2111
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0383 0.0379
Brugia malayi Protein kinase domain containing protein 0.0385 0.0692 0.0675
Plasmodium vivax serine-repeat antigen (SERA) 0.0281 0.0432 0.1504
Schistosoma mansoni tyrosine kinase 0.08 0.1725 0.1721
Trichomonas vaginalis STE family protein kinase 0.0241 0.0332 0.1222
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Entamoeba histolytica serine/threonine protein kinase, putative 0.0788 0.1695 0.6233
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0176 0.0169 0.0164
Plasmodium vivax serine/threonine kinase-1, putative 0.0449 0.0849 0.3063
Echinococcus granulosus STE20 serine:threonine protein kinase 0.144 0.3321 0.3317
Schistosoma mansoni cathepsin S (C01 family) 0.0281 0.0432 0.0427
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0292 0.0459 0.1605
Echinococcus multilocularis cyclin dependent kinase 19 0.0224 0.029 0.0285
Schistosoma mansoni serine/threonine-protein kinase 0.0479 0.0926 0.0921
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0479 0.0926 0.1625
Giardia lamblia Cathepsin L-like protease 0.0281 0.0432 0.1722
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Giardia lamblia Cathepsin L precursor 0.0281 0.0432 0.1722
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Trichomonas vaginalis AGC family protein kinase 0.0425 0.079 0.2915
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0423 0.0784 0.078
Brugia malayi Serine/threonine-protein kinase SULU 0.0648 0.1347 0.1331
Onchocerca volvulus 0.0207 0.0248 0.0853
Echinococcus granulosus cathepsin l cysteine peptidase 0.1194 0.2707 0.2704
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0325 0.0541 0.0537
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0257 0.0371 0.0366
Trichomonas vaginalis CMGC family protein kinase 0.0376 0.0668 0.2465
Giardia lamblia Aurora kinase 0.0425 0.079 0.3596
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0916 0.2014 0.6557
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Entamoeba histolytica cysteine protease, putative 0.0281 0.0432 0.1531
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Plasmodium vivax unspecified product 0.066 0.1377 0.5033
Loa Loa (eye worm) hypothetical protein 0.0375 0.0665 0.0661
Schistosoma mansoni biogenic amine (5HT) receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis serine:threonine protein kinase N2 0.0854 0.186 0.1856
Loa Loa (eye worm) AGC/PKA protein kinase 0.0292 0.0459 0.0454
Loa Loa (eye worm) hypothetical protein 0.0164 0.014 0.0135
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0873 0.1907 0.1903
Trichomonas vaginalis AGC family protein kinase 0.0516 0.1018 0.3758
Leishmania major protein kinase, putative 0.0248 0.0349 0.1057
Trichomonas vaginalis AGC family protein kinase 0.012 0.0029 0.0103
Echinococcus granulosus cyclin dependent kinase 19 0.0224 0.029 0.0285
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Trypanosoma brucei casein kinase I, isoform 2 0.0318 0.0523 0.1632
Loa Loa (eye worm) hypothetical protein 0.0317 0.0521 0.0516
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0317 0.0521 0.1837
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.0459 0.0454
Echinococcus granulosus somatostatin receptor 0.0257 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0948 0.2093 0.2089
Echinococcus granulosus dual specificity mitogen activated protein 0.0241 0.0332 0.0327
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0223 0.0286 0.0281
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0281 0.0432 0.1504
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0245 0.0342 0.0568
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0188 0.0183
Onchocerca volvulus 0.0559 0.1125 0.4116
Giardia lamblia Hypothetical protein 0.0281 0.0432 0.1722
Loa Loa (eye worm) TYRA-2 protein 0.0257 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0083 0.0078
Loa Loa (eye worm) TK/FER protein kinase 0.0796 0.1716 0.1712
Trichomonas vaginalis STE family protein kinase 0.0241 0.0332 0.1222
Entamoeba histolytica protein kinase, putative 0.0208 0.0249 0.0849
Giardia lamblia Cathepsin B precursor 0.0281 0.0432 0.1722
Onchocerca volvulus Netrin receptor homolog 0.0134 0.0064 0.0172
Echinococcus multilocularis Immunoglobulin 0.0165 0.0142 0.0138
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0167 0.0147 0.0142
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0477 0.0919 0.0915
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0352 0.0609 0.0604
Trypanosoma cruzi NIMA-related kinase, putative 0.0149 0.0103 0.0134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Echinococcus multilocularis g-protein coupled receptor 0.0257 0.0371 0.0366
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0318 0.0523 0.0895
Echinococcus granulosus tm gpcr rhodopsin 0.0257 0.0371 0.0366
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0317 0.0521 0.1625
Loa Loa (eye worm) hypothetical protein 0.0559 0.1125 0.1121
Brugia malayi intracellular kinase 0.0376 0.0668 0.0651
Echinococcus multilocularis rac serine:threonine kinase 0.0479 0.0926 0.0921
Loa Loa (eye worm) glutaminase 0.0274 0.0413 0.0408
Brugia malayi Protein kinase domain 0.0252 0.0359 0.0341
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.0523 0.0518
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Brugia malayi Cathepsin L-like precursor 0.1194 0.2707 0.2694
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0347 0.0597 0.2119
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0487 0.1796
Trichomonas vaginalis CAMK family protein kinase 0.0788 0.1695 0.626
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Echinococcus multilocularis neuropeptide s receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0477 0.0919 0.0915
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0292 0.0459 0.0454
Loa Loa (eye worm) TK protein kinase 0.0378 0.0674 0.0669
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0457 0.0871 0.3144
Entamoeba histolytica cell division protein kinase 2, putative 0.0347 0.0597 0.2144
Plasmodium falciparum serine/threonine protein kinase 0.0243 0.0338 0.1153
Brugia malayi MAP kinase sur-1 0.0245 0.0342 0.0325
Loa Loa (eye worm) hypothetical protein 0.0379 0.0676 0.0671
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0245 0.0342 0.0568
Plasmodium vivax glycogen synthase kinase 3, putative 0.0376 0.0668 0.2387
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0317 0.0521 0.1837
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0252 0.0359 0.0354
Brugia malayi Furin-like cysteine rich region family protein 0.1205 0.2734 0.2721
Brugia malayi putative neuropeptide receptor 0.0257 0.0371 0.0353
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0252 0.0359 0.0354
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0257 0.0371 0.0353
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Entamoeba histolytica cysteine protease, putative 0.0281 0.0432 0.1531
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1148 0.2594 0.259
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0788 0.1695 0.1691
Trichomonas vaginalis CAMK family protein kinase 0.0317 0.0521 0.1921
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Schistosoma mansoni tyrosine kinase 0.0282 0.0434 0.0429
Schistosoma mansoni vesicular amine transporter 0.0165 0.0142 0.0138
Loa Loa (eye worm) hypothetical protein 0.1342 0.3077 0.3074
Trypanosoma cruzi Protein kinase B 0.0479 0.0926 0.1625
Loa Loa (eye worm) hypothetical protein 0.0325 0.0541 0.0537
Echinococcus granulosus cathepsin b 0.2333 0.5548 0.5546
Onchocerca volvulus 0.1194 0.2707 1
Entamoeba histolytica protein kinase, putative 0.0836 0.1816 0.6683
Echinococcus multilocularis Rac GTPase activating protein 1 0.0122 0.0034 0.0029
Trypanosoma cruzi casein kinase, putative 0.0318 0.0523 0.0895
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0955 0.2112 0.3773
Brugia malayi Protein kinase domain containing protein 0.0224 0.029 0.0273
Brugia malayi Doublecortin family protein 0.044 0.0829 0.0812
Trichomonas vaginalis AGC family protein kinase 0.0425 0.079 0.2915
Leishmania major cathepsin L-like protease 0.1334 0.3057 1
Loa Loa (eye worm) hypothetical protein 0.0256 0.0369 0.0365
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0721 0.1529 0.1525
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0469 0.0901 0.3256
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Onchocerca volvulus 0.0325 0.0541 0.1946
Brugia malayi cathepsin Z-like cysteine proteinase 0.0485 0.0939 0.0923
Trichomonas vaginalis CAMK family protein kinase 0.0788 0.1695 0.626
Brugia malayi phosphoinositide-dependent protein kinase I 0.0239 0.0326 0.0308
Entamoeba histolytica PH domain containing protein kinase, putative 0.012 0.0029 0.0031
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0245 0.0342 0.0337
Loa Loa (eye worm) SRC-1 0.0453 0.086 0.0856
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0477 0.0919 0.0915
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2333 0.5548 0.5546
Echinococcus granulosus cathepsin l1 0.1194 0.2707 0.2704
Brugia malayi Protein kinase c protein 2 0.0338 0.0574 0.0557
Trichomonas vaginalis STE family protein kinase 0.0241 0.0332 0.1222
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0281 0.0432 0.1504
Echinococcus granulosus calcium dependent protein kinase 0.0219 0.0278 0.0273
Echinococcus multilocularis mitogen activated protein kinase 14 0.0587 0.1193 0.1189
Mycobacterium ulcerans glutaminase 0.0274 0.0413 0.594
Schistosoma mansoni tyrosine kinase 0.0889 0.1947 0.1943
Loa Loa (eye worm) hypothetical protein 0.0281 0.0432 0.0427
Echinococcus multilocularis dro:myosuppressin receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis myosin iiia 0.0248 0.0349 0.0344
Plasmodium falciparum serine repeat antigen 3 0.0281 0.0432 0.1504
Echinococcus granulosus geminin 0.017 0.0154 0.0149
Echinococcus multilocularis sex peptide receptor 0.0257 0.0371 0.0366
Brugia malayi Papain family cysteine protease containing protein 0.0281 0.0432 0.0415
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Brugia malayi Immunoglobulin I-set domain containing protein 0.0183 0.0188 0.017
Echinococcus granulosus neuropeptides capa receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis cyclin dependent kinase 1 0.0347 0.0597 0.0592
Trypanosoma cruzi casein kinase, putative 0.0318 0.0523 0.0895
Echinococcus multilocularis cysteine protease 0.1194 0.2707 0.2704
Trypanosoma brucei protein kinase, putative 0.0204 0.0239 0.0693
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0281 0.0432 0.1592
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Echinococcus granulosus twitchin 0.0312 0.0509 0.0505
Echinococcus multilocularis neuropeptides capa receptor 0.0257 0.0371 0.0366
Entamoeba histolytica protein kinase , putative 0.0425 0.079 0.2864
Schistosoma mansoni netrin receptor unc5 0.0126 0.0044 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.0597 0.0592
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0292 0.0459 0.142
Echinococcus granulosus serine:threonine protein kinase N2 0.0854 0.186 0.1856
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0542 0.1082 0.1066
Toxoplasma gondii casein kinase I 0.0318 0.0523 0.1845
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0292 0.0459 0.1605
Onchocerca volvulus 0.0257 0.0371 0.1311
Trypanosoma brucei cdc2-related kinase 1 0.0347 0.0597 0.1875
Plasmodium vivax cysteine repeat modular protein 1, putative 0.036 0.0628 0.2235
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0587 0.1193 0.1189
Giardia lamblia Kinase, NEK 0.0398 0.0722 0.3241
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0257 0.0371 0.0366
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Entamoeba histolytica protein kinase, putative 0.012 0.0029 0.0031
Echinococcus multilocularis N chimaerin 0.0223 0.0286 0.0281
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0112 0.0009 0.0004
Plasmodium vivax vivapain-3 0.066 0.1377 0.5033
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0586 0.1191 0.1186
Brugia malayi Protein kinase domain containing protein 0.0565 0.114 0.1124
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0122 0.0034 0.0029
Toxoplasma gondii histone kinase SNF1, putative 0.0262 0.0383 0.1323
Trichomonas vaginalis AGC family protein kinase 0.0246 0.0345 0.127
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0176 0.0169 0.0164
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.036 0.0628 0.0623
Entamoeba histolytica PH domain containing protein kinase, putative 0.0314 0.0514 0.1836
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0587 0.1193 0.3846
Echinococcus multilocularis Diacylglycerol kinase theta 0.0122 0.0034 0.0029
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0563 0.1133 0.1129
Onchocerca volvulus Serine\/threonine kinase homolog 0.0352 0.0609 0.2196
Brugia malayi Protein kinase domain containing protein 0.0563 0.1133 0.1117
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0168 0.015 0.0145
Echinococcus multilocularis raf serine:threonine protein kinase 0.0228 0.0299 0.0294
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Brugia malayi bone morphogenetic protein type 1 receptor 0.0176 0.0169 0.0151
Schistosoma mansoni kinase 0.0141 0.0083 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.0449 0.0849 0.0845
Schistosoma mansoni tyrosine kinase 0.0282 0.0434 0.0429
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0656 0.1366 0.1362
Loa Loa (eye worm) hypothetical protein 0.0138 0.0074 0.0069
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0239 0.0326 0.0321
Brugia malayi fibroinase precursor 0.0281 0.0432 0.0415
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0131 0.0126
Trichomonas vaginalis CAMK family protein kinase 0.0788 0.1695 0.626
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0149 0.0103 0.0276
Brugia malayi hypothetical protein 0.0201 0.0233 0.0215
Giardia lamblia Kinase, CMGC CLK 0.0449 0.0849 0.3905
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0317 0.0521 0.1837
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0453 0.086 0.0856
Giardia lamblia Cathepsin B precursor 0.0281 0.0432 0.1722
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0342 0.126
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0281 0.0432 0.1592
Schistosoma mansoni protein kinase 0.0447 0.0846 0.0841
Onchocerca volvulus 0.0257 0.0371 0.1311
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0239 0.0326 0.0321
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Echinococcus granulosus ephrin type A receptor 4 A 0.0292 0.046 0.0455
Echinococcus granulosus g protein coupled receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.025 0.0353 0.0349
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Trichomonas vaginalis AGC family protein kinase 0.0858 0.1871 0.691
Echinococcus multilocularis cyclin dependent kinase 9 0.0149 0.0102 0.0097
Brugia malayi Cathepsin L-like precursor 0.1194 0.2707 0.2694
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0542 0.1082 0.1078
Loa Loa (eye worm) hypothetical protein 0.0525 0.1041 0.1036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Echinococcus granulosus mitogen activated protein kinase 11 0.0587 0.1193 0.1189
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Mycobacterium leprae Conserved hypothetical protein 0.114 0.2573 1
Brugia malayi Protein kinase domain containing protein 0.1307 0.2988 0.2976
Echinococcus multilocularis g protein coupled receptor 0.0257 0.0371 0.0366
Trypanosoma cruzi cysteine peptidase, putative 0.1334 0.3057 0.5486
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0873 0.1907 0.7022
Loa Loa (eye worm) hypothetical protein 0.0164 0.014 0.0135
Echinococcus granulosus casein kinase I alpha 0.0318 0.0523 0.0518
Echinococcus granulosus defective proboscis extension response 0.0165 0.0142 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1194 0.2707 1
Brugia malayi Protein kinase domain containing protein 0.0347 0.0597 0.058
Echinococcus granulosus serine:threonine protein kinase N2 0.0377 0.0671 0.0667
Loa Loa (eye worm) hypothetical protein 0.0168 0.015 0.0145
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0469 0.0901 0.0897
Echinococcus multilocularis casein kinase I alpha 0.0318 0.0523 0.0518
Onchocerca volvulus 0.1194 0.2707 1
Brugia malayi Cathepsin L-like precursor 0.0815 0.1762 0.1747
Entamoeba histolytica protein kinase domain containing protein 0.0425 0.079 0.2864
Brugia malayi Papain family cysteine protease containing protein 0.0281 0.0432 0.0415
Onchocerca volvulus Cathepsin L homolog 0.0281 0.0432 0.1539
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0449 0.0849 0.2709
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0257 0.0372 0.0367
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0342 0.126
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0591 0.1203 0.1199
Echinococcus multilocularis activated cdc42 kinase 1 0.0267 0.0396 0.0391
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.036 0.0628 0.0623
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0281 0.0432 0.0427
Entamoeba histolytica cysteine protease, putative 0.0281 0.0432 0.1531
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0449 0.0849 0.1486
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0485 0.0939 0.3466
Giardia lamblia Kinase, CAMK CAMKL 0.0269 0.0402 0.1568
Chlamydia trachomatis replicative DNA helicase 0.0387 0.0695 1
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0292 0.0459 0.142
Schistosoma mansoni growth factor receptor-bound protein 0.0181 0.0183 0.0178
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0257 0.0371 0.0353
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0127 0.0048 0.0043
Trichomonas vaginalis STE family protein kinase 0.0189 0.0201 0.074
Schistosoma mansoni hypothetical protein 0.036 0.0628 0.0623
Echinococcus granulosus cathepsin l1 0.0815 0.1762 0.1758
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0252 0.0359 0.0354
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0419 0.0775 0.286
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0721 0.1529 0.1525
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis neuropeptide receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis roundabout 2 0.0127 0.0048 0.0043
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0364 0.0639 0.2015
Plasmodium falciparum protein kinase, putative 0.0204 0.0239 0.0783
Brugia malayi SRC-1 0.0453 0.086 0.0843
Schistosoma mansoni serine/threonine protein kinase 0.0295 0.0466 0.0461
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0257 0.0371 0.0353
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Loa Loa (eye worm) hypothetical protein 0.0201 0.0233 0.0228
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1069 0.2395 0.2391
Echinococcus multilocularis PAK box P21 Rho binding 0.0189 0.0201 0.0197
Loa Loa (eye worm) hypothetical protein 0.0654 0.1361 0.1357
Echinococcus granulosus dual specificity 0.0303 0.0487 0.0482
Echinococcus multilocularis transfer RNA-Thr 0.0267 0.0396 0.0391
Trypanosoma brucei protein kinase, putative 0.0253 0.0361 0.1098
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0387 0.0695 1
Plasmodium falciparum serine repeat antigen 8 0.0281 0.0432 0.1504
Echinococcus granulosus RNA directed DNA polymerase 0.0115 0.0018 0.0013
Leishmania major protein kinase, putative 0.0449 0.0849 0.2709
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0017 0.0012
Trypanosoma cruzi cysteine proteinase, putative 0.066 0.1377 0.2443
Echinococcus granulosus c-Jun N-terminal kinases 0.4119 1 1
Brugia malayi diacylglycerol kinase 0.0122 0.0034 0.0016
Entamoeba histolytica protein kinase, putative 0.0425 0.079 0.2864
Trypanosoma brucei polo-like protein kinase 0.0788 0.1695 0.5503
Echinococcus granulosus nervana 2 0.036 0.0628 0.0623
Echinococcus granulosus dro:myosuppressin receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) TK/ROR protein kinase 0.0516 0.1016 0.1012
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0916 0.2014 0.7439
Echinococcus multilocularis protein KINase family member (kin 25) 0.0168 0.015 0.0145
Loa Loa (eye worm) hypothetical protein 0.0161 0.0131 0.0126
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0317 0.0521 0.0516
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Loa Loa (eye worm) hypothetical protein 0.0267 0.0396 0.0391
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0457 0.0871 0.0866
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0654 0.1361 0.1357
Trichomonas vaginalis STE family protein kinase 0.0252 0.0359 0.1321
Echinococcus multilocularis acetylcholinesterase 0.0138 0.0074 0.0069
Plasmodium falciparum calcium-dependent protein kinase 4 0.0317 0.0521 0.1837
Brugia malayi Dopamine receptor protein 2 0.0257 0.0371 0.0353
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0257 0.0371 0.0366
Echinococcus multilocularis roundabout 2 0.0127 0.0048 0.0043
Loa Loa (eye worm) hypothetical protein 0.0122 0.0034 0.0029
Loa Loa (eye worm) TK/ABL protein kinase 0.0411 0.0755 0.075
Echinococcus multilocularis cathepsin b 0.2333 0.5548 0.5546
Onchocerca volvulus 0.036 0.0628 0.2267
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0239 0.0326 0.0321
Schistosoma mansoni cathepsin C 0.0281 0.0432 0.0427
Plasmodium falciparum calcium-dependent protein kinase 5 0.0317 0.0521 0.1837
Toxoplasma gondii kringle domain-containing protein 0.036 0.0628 0.2235
Trichomonas vaginalis STE family protein kinase 0.0252 0.0359 0.1321
Onchocerca volvulus 0.1194 0.2707 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Brugia malayi Papain family cysteine protease containing protein 0.0281 0.0432 0.0415
Loa Loa (eye worm) hypothetical protein 0.069 0.1452 0.1447
Brugia malayi AKH receptor 0.0257 0.0371 0.0353
Echinococcus multilocularis protein kinase c iota type 0.0839 0.1824 0.182
Brugia malayi cathepsin Z-like cysteine proteinase 0.0485 0.0939 0.0923
Loa Loa (eye worm) AGC/PKA protein kinase 0.0292 0.0459 0.0454
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Echinococcus multilocularis twitchin 0.0147 0.0098 0.0093
Brugia malayi Immunoglobulin I-set domain containing protein 0.0127 0.0048 0.003
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0317 0.0521 0.0516
Plasmodium falciparum calcium-dependent protein kinase 2 0.0317 0.0521 0.1837
Echinococcus multilocularis death associated protein kinase 1 0.1686 0.3935 0.3932
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0677 0.1418 0.1414
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0292 0.0459 0.0779
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Schistosoma mansoni tyrosine kinase 0.0889 0.1947 0.1943
Trichomonas vaginalis CAMK family protein kinase 0.0334 0.0563 0.2075
Schistosoma mansoni biogenic amine receptor 0.0257 0.0371 0.0366
Brugia malayi Variant SH3 domain containing protein 0.0176 0.0169 0.0151
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0425 0.079 0.0786
Loa Loa (eye worm) hypothetical protein 0.0115 0.0018 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0648 0.1347 0.1342
Trichomonas vaginalis AGC family protein kinase 0.0292 0.0459 0.1691
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0281 0.0432 0.0427
Plasmodium falciparum serine/threonine protein kinase KIN 0.0262 0.0383 0.1323
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0325 0.0541 0.0928
Echinococcus granulosus neuroglian 0.0215 0.0266 0.0261
Echinococcus granulosus neuroglian 0.0127 0.0048 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Schistosoma mansoni serine/threonine protein kinase 0.0717 0.1519 0.1515
Entamoeba histolytica hypothetical protein 0.012 0.0029 0.0031
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0223 0.0286 0.0281
Echinococcus granulosus tyrosine protein kinase Src42A 0.0453 0.086 0.0856
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0245 0.0342 0.0568
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0353 0.061 0.2169
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0357 0.0622 0.1957
Brugia malayi Pleckstrin Homology Domain 0.0144 0.0089 0.0071
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0241 0.0332 0.1
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0159 0.0128 0.0468
Schistosoma mansoni amine GPCR 0.0257 0.0371 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0788 0.1695 0.626
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0161 0.0131 0.0185
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0378 0.0674 0.0669
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0023 0.0019
Schistosoma mansoni opsin-like receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis 0.0351 0.0606 0.0601
Echinococcus granulosus insulin receptor 0.0889 0.1947 0.1943
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.066 0.1377 0.4452
Giardia lamblia Cathepsin B precursor 0.0916 0.2014 1
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0873 0.1907 0.1903
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0398 0.0722 0.2589
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0292 0.0459 0.1605
Echinococcus granulosus cyclin dependent kinase 5 0.0347 0.0597 0.0592
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0427 0.0795 0.0791
Echinococcus granulosus serine:threonine protein kinase 0.0334 0.0563 0.0558
Leishmania major protein kinase A catalytic subunit isoform 1 0.0292 0.0459 0.142
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Echinococcus granulosus cysteine protease 0.066 0.1377 0.1373
Schistosoma mansoni serine/threonine protein kinase 0.0239 0.0326 0.0321
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.066 0.1377 0.4452
Schistosoma mansoni neuropeptide receptor 0.0257 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.1148 0.2594 0.259
Leishmania major serine/threonine-protein kinase, putative 0.0149 0.0103 0.0244
Echinococcus granulosus casein kinase I alpha 0.0318 0.0523 0.0518
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0113 0.0413
Brugia malayi Protein kinase domain containing protein 0.2742 0.6567 0.6561
Schistosoma mansoni tyrosine kinase 0.08 0.1725 0.1721
Loa Loa (eye worm) hypothetical protein 0.0379 0.0676 0.0671
Entamoeba histolytica protein kinase, putative 0.0376 0.0668 0.241
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1194 0.2707 0.2704
Trypanosoma cruzi cysteine protease, putative 0.066 0.1377 0.2443
Brugia malayi Cam kinase protein 1 0.0317 0.0521 0.0504
Leishmania major cathepsin L-like protease 0.1194 0.2707 0.8846
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0587 0.1194 0.119
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0044 0.0026
Echinococcus multilocularis protein tyrosine kinase 0.1091 0.245 0.2446
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0257 0.0371 0.0366
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0127 0.0047 0.0042
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3112 0.749 0.9119
Loa Loa (eye worm) hypothetical protein 0.0379 0.0676 0.0671
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Giardia lamblia Kinase, CMGC GSK 0.0376 0.0668 0.2958
Brugia malayi Protein kinase domain containing protein 0.0586 0.1191 0.1175
Onchocerca volvulus Tyrosine kinase homolog 0.1064 0.2384 0.8798
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trichomonas vaginalis CMGC family protein kinase 0.0347 0.0597 0.22
Echinococcus granulosus roundabout 2 0.0127 0.0048 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.066 0.1377 0.5084
Echinococcus multilocularis tyrosine protein kinase 0.0572 0.1156 0.1152
Brugia malayi serine/threonine-protein kinase plk-2 0.0788 0.1695 0.168
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0352 0.0609 0.0604
Entamoeba histolytica protein kinase domain containing protein 0.0357 0.0622 0.2237
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0285 0.0441 0.0436
Echinococcus multilocularis dual specificity 0.0303 0.0487 0.0482
Schistosoma mansoni adenoreceptor 0.0257 0.0371 0.0366
Brugia malayi Immunoglobulin I-set domain containing protein 0.1221 0.2775 0.2762
Brugia malayi P38 map kinase family protein 2 0.0587 0.1193 0.1177
Brugia malayi Protein kinase domain containing protein 0.0477 0.0919 0.0903
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0796 0.1716 0.1712
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0591 0.1203 0.1199
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0788 0.1695 0.1691
Giardia lamblia Kinase, STE STE20 0.0252 0.0359 0.1339
Brugia malayi Protein kinase domain containing protein 0.0239 0.0326 0.0308
Loa Loa (eye worm) carboxylesterase 0.0138 0.0074 0.0069
Entamoeba histolytica casein kinase 1, putative 0.0318 0.0523 0.187
Giardia lamblia Cathepsin L precursor 0.0281 0.0432 0.1722
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0379 0.0676 0.0671
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0281 0.0432 0.0427
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0252 0.0359 0.0354
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0453 0.086 0.0856
Echinococcus granulosus cathepsin L cysteine protease 0.066 0.1377 0.1373
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Echinococcus multilocularis carboxylesterase 5A 0.0138 0.0074 0.0069
Brugia malayi Protein kinase domain containing protein 0.0182 0.0184 0.0166
Entamoeba histolytica protein kinase domain containing protein 0.0376 0.0668 0.241
Brugia malayi hypothetical protein 0.0164 0.014 0.0122
Trichomonas vaginalis glutaminase, putative 0.0274 0.0413 0.1521
Brugia malayi Melatonin receptor type 1A 0.0257 0.0371 0.0353
Schistosoma mansoni serine/threonine kinase 0.0477 0.0919 0.0915
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0241 0.0332 0.0327
Echinococcus multilocularis mitogen activated protein kinase 3 0.0245 0.0342 0.0337
Entamoeba histolytica cysteine protease, putative 0.0281 0.0432 0.1531
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0257 0.0371 0.0366
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0149 0.0103 0.0276
Loa Loa (eye worm) neuropeptide F receptor 0.0257 0.0371 0.0366
Echinococcus granulosus G protein coupled receptor 139 0.0257 0.0371 0.0366
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0176 0.0169 0.0164
Loa Loa (eye worm) hypothetical protein 0.0325 0.0541 0.0537
Echinococcus multilocularis unc 13 (munc13) 0.0125 0.0043 0.0038
Trypanosoma cruzi polo-like protein kinase, putative 0.0788 0.1695 0.3019
Brugia malayi serine/threonine-protein kinase PAK 7 0.0677 0.1418 0.1403
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0635 0.1313 0.1298
Brugia malayi Tachykinin-like peptides receptor 99D 0.0257 0.0371 0.0353
Loa Loa (eye worm) TK/ALK protein kinase 0.0567 0.1144 0.114
Loa Loa (eye worm) casein kinase 0.0408 0.0748 0.0744
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0282 0.0434 0.0429
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0387 0.0695 1
Echinococcus multilocularis serine threonine protein kinase 0.0596 0.1216 0.1212
Loa Loa (eye worm) hypothetical protein 0.0404 0.0737 0.0733
Onchocerca volvulus 0.0257 0.0371 0.1311
Echinococcus granulosus cyclin dependent kinase 7 0.0172 0.016 0.0155
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis dual specificity 0.0357 0.0622 0.0617
Schistosoma mansoni serine/threonine protein kinase 0.0355 0.0615 0.061
Trichomonas vaginalis CMGC family protein kinase 0.0347 0.0597 0.22
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0281 0.0432 0.0427
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0425 0.079 0.2864
Echinococcus granulosus activated cdc42 kinase 1 0.0267 0.0396 0.0391
Brugia malayi Protein kinase domain containing protein 0.0352 0.0609 0.0592
Loa Loa (eye worm) hypothetical protein 0.0281 0.0432 0.0427
Schistosoma mansoni opsin-like receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0257 0.0371 0.0366
Entamoeba histolytica cysteine proteinase, putative 0.066 0.1377 0.5049
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0223 0.0286 0.0281
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0749 0.1598 0.1594
Loa Loa (eye worm) hypothetical protein 0.0406 0.0742 0.0737
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0248 0.0349 0.1222
Echinococcus multilocularis rho associated protein kinase 0.0948 0.2093 0.2089
Loa Loa (eye worm) thyroid receptor interactor 0.0291 0.0457 0.0453
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Brugia malayi RhoGAP domain containing protein 0.0223 0.0286 0.0269
Schistosoma mansoni amine GPCR 0.0257 0.0371 0.0366
Echinococcus granulosus alpha 1A adrenergic receptor 0.0257 0.0371 0.0366
Plasmodium falciparum casein kinase 1 0.0318 0.0523 0.1845
Echinococcus granulosus neuropeptide Y receptor 0.0257 0.0371 0.0366
Trypanosoma brucei rac serine-threonine kinase, putative 0.0858 0.1871 0.6084
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Trypanosoma cruzi cruzipain precursor, putative 0.0379 0.0676 0.1172
Schistosoma mansoni biogenic amine receptor 0.0257 0.0371 0.0366
Leishmania major hypothetical protein, conserved 0.036 0.0628 0.1977
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Schistosoma mansoni protein kinase 0.1286 0.2937 0.2933
Brugia malayi putative neuropeptide receptor NPR1 0.0257 0.0371 0.0353
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0257 0.0371 0.1311
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Onchocerca volvulus 0.022 0.028 0.0973
Loa Loa (eye worm) hypothetical protein 0.026 0.0378 0.0374
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0262 0.0383 0.1171
Trypanosoma cruzi major cysteine proteinase, putative 0.0421 0.0781 0.1363
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0125 0.0043 0.0038
Echinococcus granulosus tyrosine protein kinase HCK 0.0277 0.0422 0.0417
Echinococcus multilocularis serotonin receptor 0.0375 0.0665 0.0661
Leishmania major protein kinase, putative 0.0204 0.0239 0.0693
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0318 0.0523 0.0518
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0281 0.0432 0.0427
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0262 0.0383 0.1171
Giardia lamblia Cathepsin B precursor 0.0485 0.0939 0.4375
Schistosoma mansoni growth factor receptor-bound protein 0.0176 0.0169 0.0164
Giardia lamblia Kinase, STE STE20 0.0241 0.0332 0.1198
Plasmodium vivax protein kinase, putative 0.015 0.0105 0.0284
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0257 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0685 0.1439 0.1435
Toxoplasma gondii aurora kinase 0.0425 0.079 0.2842
Echinococcus multilocularis tyrosine protein kinase Srms 0.0378 0.0674 0.0669
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0248 0.0349 0.1057
Echinococcus multilocularis neuropeptides capa receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0325 0.0541 0.0537
Onchocerca volvulus 0.0178 0.0175 0.0583
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0635 0.1313 0.1309
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0172 0.016 0.0155
Schistosoma mansoni cell adhesion molecule 0.0127 0.0048 0.0043
Brugia malayi larval opioid receptor 0.0257 0.0371 0.0353
Schistosoma mansoni tyrosine kinase 0.0622 0.1281 0.1277
Brugia malayi Protein kinase domain containing protein 0.0334 0.0563 0.0545
Onchocerca volvulus 0.0183 0.0188 0.0632
Entamoeba histolytica cell division protein kinase 2, putative 0.0355 0.0616 0.2215
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1194 0.2707 0.2704
Plasmodium falciparum NIMA related kinase 4 0.0149 0.0103 0.0276
Echinococcus granulosus Rac GTPase activating protein 1 0.0122 0.0034 0.0029
Trypanosoma cruzi cysteine peptidase, putative 0.066 0.1377 0.2443
Schistosoma mansoni tyrosine kinase 0.0197 0.0223 0.0218
Echinococcus granulosus serine/threonine protein kinase 0.0479 0.0926 0.0921
Schistosoma mansoni protein kinase 0.0293 0.0461 0.0456
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0103 0.0376
Brugia malayi Immunoglobulin I-set domain containing protein 0.0201 0.0233 0.0215
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0225 0.0291 0.0287
Loa Loa (eye worm) hypothetical protein 0.0186 0.0195 0.019
Echinococcus granulosus orexin receptor type 2 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Echinococcus granulosus Protein kinase C brain isozyme 0.0717 0.1519 0.1515
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0127 0.0048 0.0043
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0453 0.086 0.0856
Loa Loa (eye worm) hypothetical protein 0.0122 0.0034 0.0029
Onchocerca volvulus 0.0257 0.0371 0.1311
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0352 0.0609 0.0604
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0245 0.0342 0.1035
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0248 0.0349 0.058
Schistosoma mansoni hypothetical protein 0.0122 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.0815 0.1762 0.1758
Trichomonas vaginalis STE family protein kinase 0.0248 0.0349 0.1285
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0477 0.0919 0.0915
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0112 0.0009 0.0004
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Onchocerca volvulus 0.0207 0.0248 0.0853
Echinococcus multilocularis cyclin dependent kinase 0.0347 0.0597 0.0592
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0122 0.0034 0.0029
Brugia malayi Protein kinase domain containing protein 0.0873 0.1907 0.1892
Echinococcus granulosus cGMP dependent protein kinase 1 0.0295 0.0466 0.0461
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0447 0.0846 0.0841
Schistosoma mansoni amine GPCR 0.0257 0.0371 0.0366
Giardia lamblia Cathepsin B precursor 0.0916 0.2014 1
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Brugia malayi neuropeptide F receptor 0.0257 0.0371 0.0353
Entamoeba histolytica cysteine proteinase, putative 0.066 0.1377 0.5049
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0241 0.0332 0.0314
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0425 0.079 0.0786
Onchocerca volvulus 0.0207 0.0248 0.0853
Echinococcus granulosus protein kinase c epsilon type 0.0602 0.1232 0.1227
Loa Loa (eye worm) hypothetical protein 0.0404 0.0737 0.0733
Echinococcus multilocularis growth factor receptor bound protein 2 0.0176 0.0169 0.0164
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0209 0.0253 0.0248
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0281 0.0432 0.1592
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0423 0.0785 0.0781
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0357 0.0622 0.1957
Trypanosoma cruzi cysteine peptidase, putative 0.1194 0.2707 0.4853
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0347 0.0597 0.1875
Onchocerca volvulus 0.0125 0.0043 0.0094
Echinococcus multilocularis mitogen activated protein kinase 11 0.0587 0.1193 0.1189
Onchocerca volvulus 0.0257 0.0371 0.1311
Schistosoma mansoni tyrosine kinase 0.1091 0.245 0.2446
Echinococcus granulosus mitogen activated protein kinase 14 0.0587 0.1193 0.1189
Schistosoma mansoni serine/threonine protein kinase 0.0427 0.0795 0.0791
Loa Loa (eye worm) hypothetical protein 0.0207 0.0248 0.0243
Entamoeba histolytica cysteine proteinase 1, putative 0.066 0.1377 0.5049
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.144 0.3321 0.3317
Echinococcus multilocularis roundabout 2 0.0292 0.046 0.0455
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0252 0.0359 0.0354
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Toxoplasma gondii NEK kinase 0.0149 0.0103 0.0276
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0836 0.1816 0.1812
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0217 0.0271 0.0266
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2333 0.5548 0.5546
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0292 0.0459 0.142
Schistosoma mansoni serine/threonine protein kinase 0.0717 0.1519 0.1515
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Echinococcus multilocularis tyrosine protein kinase Blk 0.0378 0.0674 0.0669
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0317 0.0521 0.0516
Echinococcus granulosus cyclin dependent kinase 0.0347 0.0597 0.0592
Loa Loa (eye worm) CDC7 protein kinase 0.0153 0.0113 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0376 0.0668 0.0664
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Trichomonas vaginalis CAMK family protein kinase 0.0514 0.1012 0.3736
Echinococcus multilocularis cathepsin L 0.066 0.1377 0.1373
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0654 0.1361 0.1357
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0237 0.0322 0.1096
Loa Loa (eye worm) hypothetical protein 0.0124 0.004 0.0035
Loa Loa (eye worm) AUR protein kinase 0.0425 0.079 0.0786
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Brugia malayi Immunoglobulin I-set domain containing protein 0.0637 0.1318 0.1302
Schistosoma mansoni tyrosine kinase 0.0521 0.1029 0.1025
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Entamoeba histolytica protein kinase, putative 0.012 0.0029 0.0031
Echinococcus multilocularis tyrosine protein kinase HCK 0.0277 0.0422 0.0417
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0245 0.0342 0.1035
Plasmodium vivax protein kinase Crk2 0.0347 0.0597 0.2119
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Trichomonas vaginalis STE family protein kinase 0.0398 0.0722 0.2665
Echinococcus granulosus tyrosine kinase 0.0378 0.0674 0.0669
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trypanosoma cruzi casein kinase, putative 0.0318 0.0523 0.0895
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Schistosoma mansoni hypothetical protein 0.0257 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0542 0.1082 0.1078
Trypanosoma cruzi cdc2-related kinase 3 0.0347 0.0597 0.1029
Loa Loa (eye worm) AGC/AKT protein kinase 0.0858 0.1871 0.1867
Leishmania major casein kinase, putative 0.0318 0.0523 0.1632
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0161 0.0131 0.0113
Brugia malayi putative serine/threonine kinase SADA gamma 0.0262 0.0383 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0788 0.1695 0.626
Entamoeba histolytica diacylglycerol kinase, putative 0.0122 0.0034 0.0051
Brugia malayi Kinase associated domain 1 family protein 0.0257 0.0372 0.0354
Echinococcus multilocularis nervana 2 0.036 0.0628 0.0623
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0204 0.0239 0.0783
Schistosoma mansoni hypothetical protein 0.017 0.0154 0.0149
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus multilocularis cyclin dependent kinase 1 0.0347 0.0597 0.0592
Echinococcus multilocularis myotubularin protein 13 0.0144 0.0089 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0103 0.0098
Toxoplasma gondii NEK kinase 0.0149 0.0103 0.0276
Trichomonas vaginalis CAMK family protein kinase 0.0788 0.1695 0.626
Plasmodium vivax unspecified product 0.0281 0.0432 0.1504
Schistosoma mansoni protein kinase 0.0563 0.1133 0.1129
Trypanosoma cruzi cysteine proteinase, putative 0.066 0.1377 0.2443
Schistosoma mansoni tyrosine kinase 0.0197 0.0223 0.0218
Schistosoma mansoni tyrosine kinase 0.0694 0.1461 0.1456
Giardia lamblia Cysteine protease 0.0281 0.0432 0.1722
Schistosoma mansoni protein kinase 0.1286 0.2937 0.2933
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0325 0.0541 0.0537
Toxoplasma gondii preprocathepsin c precursor, putative 0.0469 0.0901 0.3256
Plasmodium falciparum serine repeat antigen 4 0.0281 0.0432 0.1504
Brugia malayi protein unc-22 0.0183 0.0188 0.017
Loa Loa (eye worm) cysteine protease 0.1194 0.2707 0.2704
Brugia malayi GnHR receptor homolog 0.0257 0.0371 0.0353
Loa Loa (eye worm) hypothetical protein 0.0122 0.0034 0.0029
Echinococcus multilocularis calcium activated potassium channel 0.0355 0.0615 0.061
Giardia lamblia Kinase, CMGC GSK 0.0376 0.0668 0.2958
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0487 0.1796
Echinococcus granulosus Diacylglycerol kinase theta 0.0122 0.0034 0.0029
Echinococcus granulosus roundabout 2 0.0127 0.0048 0.0043
Loa Loa (eye worm) glutaminase 2 0.0274 0.0413 0.0408
Trichomonas vaginalis AGC family protein kinase 0.0425 0.079 0.2915
Plasmodium vivax casein kinase 1, putative 0.0318 0.0523 0.1845
Trypanosoma cruzi cysteine peptidase, putative 0.1334 0.3057 0.5486
Brugia malayi serine/threonine kinase 12 0.0425 0.079 0.0773
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0281 0.0432 0.0427
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0347 0.0597 0.0592
Schistosoma mansoni opsin-like receptor 0.0257 0.0371 0.0366
Brugia malayi Variant SH3 domain containing protein 0.0223 0.0286 0.0269
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0125 0.0043 0.0038
Onchocerca volvulus 0.0207 0.0248 0.0853
Echinococcus granulosus g protein coupled receptor 0.0257 0.0371 0.0366
Schistosoma mansoni cathepsin B (C01 family) 0.0281 0.0432 0.0427
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0292 0.0459 0.0454
Brugia malayi Protein kinase domain containing protein 0.0357 0.0622 0.0605
Plasmodium vivax vivapain-2 0.1194 0.2707 1
Echinococcus multilocularis neuropeptide Y receptor 0.0257 0.0371 0.0366
Echinococcus granulosus calcium activated potassium channel 0.0355 0.0615 0.061
Echinococcus granulosus tm gpcr rhodopsin 0.0257 0.0371 0.0366
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Leishmania major protein kinase, putative 0.0149 0.0103 0.0244
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0223 0.0286 0.0281
Schistosoma mansoni tyrosine kinase 0.0603 0.1235 0.1231
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0788 0.1695 0.5503
Schistosoma mansoni cathepsin F (C01 family) 0.1194 0.2707 0.2704
Entamoeba histolytica hypothetical protein 0.012 0.0029 0.0031
Echinococcus multilocularis allatostatin A receptor 0.0257 0.0371 0.0366
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0194 0.0216 0.0211
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1194 0.2707 0.2704
Plasmodium falciparum cysteine proteinase falcipain 1 0.066 0.1377 0.5033
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0423 0.0784 0.078
Loa Loa (eye worm) hypothetical protein 0.0176 0.0169 0.0164
Brugia malayi Protein kinase domain containing protein 0.0516 0.1018 0.1002
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0243 0.0338 0.0559
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Brugia malayi RhoGAP domain containing protein 0.0122 0.0034 0.0016
Entamoeba histolytica serine/threonine protein kinase, putative 0.0262 0.0383 0.135
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0245 0.0342 0.1035
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0257 0.0371 0.0353
Loa Loa (eye worm) hypothetical protein 0.1194 0.2707 0.2704
Loa Loa (eye worm) hypothetical protein 0.0281 0.0432 0.0427
Trypanosoma cruzi cruzipain precursor, putative 0.1334 0.3057 0.5486
Echinococcus multilocularis expressed conserved protein 0.0295 0.0466 0.0461
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0453 0.086 0.0856
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0449 0.0849 0.0845
Schistosoma mansoni serine/threonine protein kinase 0.0357 0.0622 0.0617
Echinococcus granulosus epidermal growth factor receptor 0.1205 0.2734 0.2731
Echinococcus granulosus tyrosine protein kinase ABL1 0.0411 0.0755 0.075
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0453 0.086 0.0856
Trichomonas vaginalis CK1 family protein kinase 0.0318 0.0523 0.1928
Echinococcus multilocularis tyrosine kinase 0.0207 0.0248 0.0243
Leishmania major casein kinase II, putative 0.0293 0.0461 0.1427
Echinococcus multilocularis serine:threonine protein kinase 38 0.0477 0.0919 0.0915
Brugia malayi Cathepsin L-like precursor 0.1194 0.2707 0.2694
Trichomonas vaginalis CK1 family protein kinase 0.0318 0.0523 0.1928
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0257 0.0372 0.0367
Schistosoma mansoni serine/threonine protein kinase 0.0602 0.1232 0.1227
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0352 0.0609 0.0604
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0281 0.0432 0.0415
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0916 0.2014 0.201
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0342 0.126
Echinococcus granulosus neuropeptides capa receptor 0.0257 0.0371 0.0366
Giardia lamblia Cysteine protease 0.0281 0.0432 0.1722
Loa Loa (eye worm) AGC/NDR protein kinase 0.0477 0.0919 0.0915
Trichomonas vaginalis AGC family protein kinase 0.0398 0.0722 0.2665
Brugia malayi Dopamine receptor protein 1 0.0257 0.0371 0.0353
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0347 0.0597 0.0592
Onchocerca volvulus Cathepsin F homolog 0.1194 0.2707 1
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0423 0.0785 0.0781
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0685 0.1439 0.1435
Giardia lamblia Cysteine protease 0.0281 0.0432 0.1722
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.069 0.1452 0.1447
Trypanosoma brucei cysteine peptidase C (CPC) 0.0916 0.2014 0.6557
Echinococcus granulosus Vam6:Vps39 protein 0.0325 0.0541 0.0537
Onchocerca volvulus 0.0257 0.0371 0.1311
Echinococcus granulosus casein kinase i 0.0318 0.0523 0.0518
Entamoeba histolytica PH domain containing protein kinase, putative 0.0479 0.0926 0.3369
Echinococcus multilocularis casein kinase I alpha 0.0318 0.0523 0.0518
Brugia malayi follicle stimulating hormone receptor 0.0257 0.0371 0.0353
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Schistosoma mansoni neuropeptide F-like receptor 0.0257 0.0371 0.0366
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0257 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.029 0.0285
Giardia lamblia Kinase, NEK 0.0398 0.0722 0.3241
Trypanosoma brucei protein kinase, putative 0.0376 0.0668 0.2111
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0257 0.0371 0.0366
Brugia malayi protein-tyrosine kinase 0.0378 0.0674 0.0657
Loa Loa (eye worm) hypothetical protein 0.0228 0.03 0.0296
Toxoplasma gondii cathepsin CPC1 0.0469 0.0901 0.3256
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0243 0.0338 0.102
Echinococcus granulosus neuropeptide Y receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0257 0.0371 0.0366
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0292 0.0459 0.0779
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0241 0.0332 0.1
Loa Loa (eye worm) hypothetical protein 0.0125 0.0043 0.0038
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0262 0.0383 0.0642
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0243 0.0338 0.102
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Echinococcus multilocularis 0.0447 0.0846 0.0841
Leishmania major protein kinase, putative 0.0425 0.079 0.2514
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0514 0.1012 0.1008
Entamoeba histolytica protein kinase, putative 0.0239 0.0326 0.1136
Loa Loa (eye worm) hypothetical protein 0.0184 0.0189 0.0185
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0587 0.1194 0.119
Plasmodium vivax unspecified product 0.0293 0.0461 0.1613
Brugia malayi hypothetical protein 0.0207 0.0248 0.023
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0149 0.0103 0.0244
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.1069 0.2395 0.2391
Brugia malayi ORL1-like opioid receptor 0.0257 0.0371 0.0353
Entamoeba histolytica protein kinase, putative 0.0858 0.1871 0.6887
Brugia malayi Carboxylesterase family protein 0.0138 0.0074 0.0056
Brugia malayi G-protein coupled receptor 0.0257 0.0371 0.0353
Onchocerca volvulus 0.0257 0.0371 0.1311
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0469 0.0901 0.3256
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0586 0.1191 0.1187
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0353 0.061 0.2653
Echinococcus granulosus activated cdc42 kinase 1 0.0267 0.0396 0.0391
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0478 0.0923 0.0918
Trypanosoma brucei cdc2-related kinase 3 0.0347 0.0597 0.1875
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0487 0.0482
Echinococcus granulosus cyclin dependent kinase 9 0.0141 0.0083 0.0078
Echinococcus granulosus neuropeptide receptor 0.0257 0.0371 0.0366
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0317 0.0521 0.1837
Toxoplasma gondii cathepsin CPL 0.1194 0.2707 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0815 0.1762 0.6508
Trichomonas vaginalis conserved hypothetical protein 0.0281 0.0432 0.1592
Brugia malayi G protein-coupled receptor 0.0257 0.0371 0.0353
Plasmodium vivax tyrosine kinase-like protein, putative 0.0237 0.0322 0.1096
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0325 0.0541 0.0928
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0209 0.0253 0.0235
Echinococcus multilocularis Glutaredoxin protein 5 0.036 0.0628 0.0623
Echinococcus multilocularis neuropeptide receptor 0.0257 0.0371 0.0366
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2333 0.5548 0.5546
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Brugia malayi p70 ribosomal S6 kinase beta 0.0836 0.1816 0.1801
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Echinococcus multilocularis NCK adaptor protein 0.0181 0.0183 0.0178
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.0372 0.1369
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.1286 0.2937 0.2933
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Echinococcus granulosus casein kinase I alpha 0.0318 0.0523 0.0518
Loa Loa (eye worm) hypothetical protein 0.0122 0.0034 0.0029
Loa Loa (eye worm) protein kinase domain-containing protein 0.0506 0.0992 0.0987
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0149 0.0103 0.0134
Echinococcus multilocularis serine:threonine protein kinase 3 0.0749 0.1598 0.1594
Echinococcus granulosus tyrosine protein kinase Fyn 0.0453 0.086 0.0856
Loa Loa (eye worm) hypothetical protein 0.026 0.0378 0.0374
Entamoeba histolytica protein kinase domain containing protein 0.0141 0.0083 0.0232
Brugia malayi Variant SH3 domain containing protein 0.0176 0.0169 0.0151
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Brugia malayi Protein kinase domain containing protein 0.0157 0.0122 0.0104
Plasmodium vivax serine/threonine protein kinase, putative 0.0243 0.0338 0.1153
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0334 0.0563 0.0558
Echinococcus multilocularis fmrfamide receptor 0.0257 0.0371 0.0366
Echinococcus granulosus cathepsin b 0.2333 0.5548 0.5546
Onchocerca volvulus Cathepsin L homolog 0.1194 0.2707 1
Echinococcus granulosus fibroblast growth factor receptor 4 0.0587 0.1194 0.119
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0161 0.0131 0.0126
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Loa Loa (eye worm) TK protein kinase 0.0277 0.0422 0.0417
Entamoeba histolytica protein kinase, putative 0.0321 0.053 0.1896
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0449 0.0849 0.1486
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0317 0.0521 0.0516
Plasmodium falciparum NIMA related kinase 2 0.0149 0.0103 0.0276
Schistosoma mansoni tyrosine kinase 0.031 0.0503 0.0498
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0303 0.0487 0.1514
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0453 0.086 0.0856
Brugia malayi cathepsin B-like cysteine proteinase 0.2333 0.5548 0.554
Trypanosoma cruzi polo-like protein kinase, putative 0.0788 0.1695 0.3019
Loa Loa (eye worm) camk/dcamkl protein kinase 0.044 0.0829 0.0824
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0587 0.1193 0.3846
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Echinococcus multilocularis neuropeptide receptor A26 0.0257 0.0371 0.0366
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1194 0.2707 1
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0262 0.0383 0.0379
Entamoeba histolytica diacylglycerol kinase, putative 0.0122 0.0034 0.0051
Entamoeba histolytica protein kinase, putative 0.0303 0.0487 0.1737
Loa Loa (eye worm) hypothetical protein 0.0122 0.0034 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1194 0.2707 1
Echinococcus multilocularis CDC7 cell division cycle 7 0.0153 0.0113 0.0108
Loa Loa (eye worm) TK/FER protein kinase 0.0207 0.0248 0.0243
Giardia lamblia Kinase, STE STE20 0.0248 0.0349 0.1288
Echinococcus granulosus tyrosine protein kinase Srms 0.0999 0.2221 0.2217
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0449 0.0849 0.3063
Echinococcus multilocularis dual specificity protein kinase clk2 0.0449 0.0849 0.0845
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0347 0.0597 0.0592
Giardia lamblia Kinase, CMGC CDK 0.0347 0.0597 0.2583
Echinococcus granulosus serine:threonine kinase SAD 1 0.0262 0.0383 0.0379
Schistosoma mansoni cathepsin s 0.0379 0.0676 0.0671
Loa Loa (eye worm) TK/EGFR protein kinase 0.1205 0.2734 0.2731
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Loa Loa (eye worm) hypothetical protein 0.0416 0.0767 0.0762
Brugia malayi neuropeptide F receptor 0.0257 0.0371 0.0353
Echinococcus multilocularis serine:threonine protein kinase N2 0.0477 0.0919 0.0915
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0293 0.0461 0.0456
Schistosoma mansoni neuropeptide receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0243 0.0338 0.0333
Echinococcus multilocularis serotonin receptor 0.0375 0.0665 0.0661
Schistosoma mansoni cell adhesion molecule 0.0127 0.0048 0.0043
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0138 0.0074 0.0069
Toxoplasma gondii AGC kinase 0.0836 0.1816 0.6672
Plasmodium falciparum serine repeat antigen 6 0.0281 0.0432 0.1504
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1194 0.2707 1
Brugia malayi Cathepsin L-like precursor 0.1194 0.2707 0.2694
Echinococcus multilocularis TGF beta receptor type 1 0.0167 0.0147 0.0142
Trypanosoma cruzi cdc2-related kinase 1 0.0347 0.0597 0.1029
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Brugia malayi serine/threonine protein kinase 6 0.0425 0.079 0.0773
Echinococcus granulosus cyclin dependent kinase 1 0.0347 0.0597 0.0592
Echinococcus granulosus protein tyrosine kinase 0.1091 0.245 0.2446
Echinococcus multilocularis orexin receptor type 2 0.0257 0.0371 0.0366
Echinococcus multilocularis mitogen activated protein kinase 0.0245 0.0342 0.0337
Echinococcus granulosus unc 13 munc13 0.0125 0.0043 0.0038
Giardia lamblia Kinase, AGC PKA 0.0292 0.0459 0.1863
Echinococcus granulosus protein kinase c eta type 0.0122 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.2333 0.5548 0.5546
Trypanosoma cruzi casein kinase, delta isoform, putative 0.022 0.028 0.0455
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0325 0.0541 0.0537
Onchocerca volvulus 0.0815 0.1762 0.6486
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0165 0.0142 0.0138
Brugia malayi Protein kinase domain containing protein 0.0572 0.1156 0.114
Toxoplasma gondii cathepsin CPC2 0.0353 0.061 0.2169
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0295 0.0466 0.0461
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0487 0.1796
Schistosoma mansoni atypical protein kinase C 0.0857 0.1868 0.1864
Echinococcus granulosus sex peptide receptor 0.0257 0.0371 0.0366
Onchocerca volvulus 0.1194 0.2707 1
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0161 0.0131 0.0126
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0149 0.0103 0.0134
Plasmodium falciparum calcium-dependent protein kinase 1 0.0317 0.0521 0.1837
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0281 0.0432 0.0427
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0165 0.0142 0.0138
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0262 0.0383 0.0379
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Echinococcus multilocularis mitogen activated protein kinase 11 0.0587 0.1193 0.1189
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0281 0.0432 0.1592
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0159 0.0128 0.0468
Loa Loa (eye worm) twinkle helicase 0.011 0.0006 0.0001
Echinococcus granulosus roundabout 2 0.0292 0.046 0.0455
Echinococcus granulosus casein kinase ii subunit alpha 0.0293 0.0461 0.0456
Loa Loa (eye worm) hypothetical protein 0.0375 0.0665 0.0661
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0023 0.0019
Entamoeba histolytica PH domain containing protein kinase, putative 0.012 0.0029 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0295 0.0466 0.0461
Brugia malayi Hr1 repeat family protein 0.0854 0.186 0.1845
Trichomonas vaginalis CMGC family protein kinase 0.0293 0.0461 0.1699
Toxoplasma gondii NEK kinase 0.0149 0.0103 0.0276
Onchocerca volvulus 0.1194 0.2707 1
Loa Loa (eye worm) CAMK protein kinase 0.0183 0.0188 0.0183
Mycobacterium ulcerans hypothetical protein 0.0197 0.0223 0.3207
Echinococcus multilocularis casein kinase ii subunit alpha 0.0293 0.0461 0.0456
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0116 0.0423
Brugia malayi Papain family cysteine protease containing protein 0.066 0.1377 0.1361
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1194 0.2707 1
Giardia lamblia Kinase, CMGC DYRK 0.0303 0.0487 0.2011
Echinococcus multilocularis dual specificity mitogen activated protein 0.0241 0.0332 0.0327
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0281 0.0432 0.0427
Schistosoma mansoni ephrin receptor 0.0142 0.0086 0.0081
Schistosoma mansoni hypothetical protein 0.0257 0.0371 0.0366
Brugia malayi Protein kinase domain containing protein 0.0506 0.0992 0.0975
Echinococcus granulosus neuropeptide FF receptor 2 0.0257 0.0371 0.0366
Entamoeba histolytica hypothetical protein 0.0357 0.0622 0.2237
Brugia malayi RE15519p 0.0257 0.0371 0.0353
Loa Loa (eye worm) neuropeptide F receptor 0.0257 0.0371 0.0366
Echinococcus granulosus expressed protein 0.0243 0.0338 0.0333
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0648 0.1347 0.1342
Schistosoma mansoni tyrosine kinase 0.0587 0.1194 0.119
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0284 0.0279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0281 0.0432 0.1592
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0453 0.086 0.0856
Schistosoma mansoni serine/threonine protein kinase 0.0591 0.1203 0.1199
Echinococcus granulosus 7TM GPCR rhodopsin 0.0257 0.0371 0.0366
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0281 0.0432 0.1592
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0357 0.0622 0.0617
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0281 0.0432 0.1531
Echinococcus multilocularis cysteine protease 0.1194 0.2707 0.2704
Brugia malayi Cathepsin L-like precursor 0.0815 0.1762 0.1747
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Entamoeba histolytica protein kinase, putative 0.0858 0.1871 0.6887
Echinococcus multilocularis hypothetical protein 0.0257 0.0372 0.0367
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0717 0.1519 0.1515
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0237 0.0322 0.1096
Leishmania major cathepsin L-like protease 0.1334 0.3057 1
Trichomonas vaginalis CAMK family protein kinase 0.0369 0.0652 0.2403
Echinococcus multilocularis cathepsin L cysteine protease 0.1194 0.2707 0.2704
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0873 0.1907 0.1892
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0208 0.0249 0.0244
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1862 0.4373 0.437
Onchocerca volvulus 0.0186 0.0195 0.0658
Entamoeba histolytica PH domain containing protein kinase, putative 0.0479 0.0926 0.3369
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Schistosoma mansoni serine/threonine kinase 0.0522 0.1031 0.1027
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0353 0.061 0.2653
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0317 0.0521 0.0516
Entamoeba histolytica protein kinase, putative 0.0357 0.0622 0.2237
Trypanosoma cruzi aurora B kinase, putative 0.0425 0.079 0.1379
Echinococcus multilocularis aurora kinase A 0.0425 0.079 0.0786
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.3391 0.8185 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0257 0.0371 0.0353
Echinococcus multilocularis cyclin dependent kinase 9 0.0141 0.0083 0.0078
Echinococcus granulosus neuropeptide s receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis tissue type plasminogen activator 0.036 0.0628 0.0623
Loa Loa (eye worm) AGC/PKN protein kinase 0.0854 0.186 0.1856
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0303 0.0487 0.0482
Schistosoma mansoni adapter molecule crk 0.0176 0.0169 0.0164
Schistosoma mansoni growth hormone secretagogue receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis titin 0.0183 0.0188 0.0183
Schistosoma mansoni neuropeptide receptor 0.0257 0.0371 0.0366
Schistosoma mansoni nephrin 0.0251 0.0357 0.0352
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0257 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0383 0.0379
Echinococcus granulosus casein kinase I gamma 0.0506 0.0992 0.0987
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.0372 0.1369
Toxoplasma gondii cathepsin B 0.0916 0.2014 0.7412
Loa Loa (eye worm) gastrulation defective protein 1 0.0127 0.0047 0.0042
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0209 0.0253 0.0248
Echinococcus multilocularis serine:threonine protein kinase 0.0334 0.0563 0.0558
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Plasmodium falciparum glycogen synthase kinase 3 0.0376 0.0668 0.2387
Leishmania major protein kinase A catalytic subunit 0.0292 0.0459 0.142
Echinococcus granulosus myotubularin protein 13 0.0144 0.0089 0.0084
Trypanosoma cruzi casein kinase, putative 0.0318 0.0523 0.0895
Entamoeba histolytica protein kinase domain containing protein 0.0293 0.0461 0.1639
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1194 0.2707 1
Plasmodium falciparum cysteine repeat modular protein 1 0.036 0.0628 0.2235
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0342 0.0337
Onchocerca volvulus 0.0257 0.0371 0.1311
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Entamoeba histolytica protein kinase, putative 0.0317 0.0521 0.1862
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0376 0.0668 0.0664
Entamoeba histolytica cysteine proteinase, putative 0.066 0.1377 0.5049
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Leishmania major cathepsin L-like protease 0.1194 0.2707 0.8846
Schistosoma mansoni serine/threonine protein kinase 0.0873 0.1907 0.1903
Echinococcus granulosus serotonin receptor 0.0257 0.0371 0.0366
Loa Loa (eye worm) TK protein kinase 0.0637 0.1318 0.1314
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0137 0.0073 0.0265
Loa Loa (eye worm) hypothetical protein 0.0346 0.0594 0.0589
Loa Loa (eye worm) ctsf protein 0.1194 0.2707 0.2704
Echinococcus multilocularis casein kinase I delta 0.0318 0.0523 0.0518
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0257 0.0371 0.0366
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0281 0.0432 0.1504
Echinococcus multilocularis ephrin type A receptor 4 A 0.0292 0.046 0.0455
Echinococcus granulosus tyrosine protein kinase Fyn 0.0453 0.086 0.0856
Giardia lamblia Kinase, CMGC MAPK 0.0245 0.0342 0.1253
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.0992 0.0987
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0516 0.1018 0.1014
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0425 0.079 0.2864
Brugia malayi Tyrosine-protein kinase abl-1 0.0126 0.0044 0.0026
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0141 0.0083 0.0078
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0161 0.0131 0.0481
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0347 0.0597 0.0592
Brugia malayi Temporarily assigned gene name protein 59 0.0375 0.0666 0.065
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0342 0.0584 0.0567
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0457 0.0871 0.0866
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0873 0.1907 0.1903
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0073 0.0265
Entamoeba histolytica cysteine protease, putative 0.0281 0.0432 0.1531
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0685 0.1439 0.1435
Onchocerca volvulus 0.0207 0.0248 0.0853
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0338 0.0333
Brugia malayi sulfakinin receptor protein 0.0257 0.0371 0.0353
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0257 0.0371 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0262 0.0383 0.1412
Loa Loa (eye worm) hypothetical protein 0.0281 0.0432 0.0427
Schistosoma mansoni rac gtpase activating protein 0.0122 0.0034 0.0029
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0208 0.0249 0.0244
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.0459 0.0454
Brugia malayi Protein kinase domain containing protein 0.0993 0.2205 0.2191
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0128 0.0468
Echinococcus granulosus protein kinase C gamma type 0.0596 0.1216 0.1212
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0137 0.0073 0.0265
Echinococcus multilocularis tyrosine protein kinase shark 0.0622 0.1281 0.1277
Brugia malayi STE20-like kinase MST 0.0749 0.1598 0.1582
Loa Loa (eye worm) IKK protein kinase 0.0993 0.2205 0.2202
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0485 0.0939 0.3466
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Entamoeba histolytica protein kinase, putative 0.0211 0.0256 0.0878
Giardia lamblia Cathepsin L precursor 0.0281 0.0432 0.1722
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0257 0.0371 0.0366
Brugia malayi hypothetical protein 0.0257 0.0371 0.0353
Schistosoma mansoni unc-13 (munc13) 0.0125 0.0043 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1334 0.3057 1
Schistosoma mansoni biogenic amine receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0411 0.0755 0.075
Giardia lamblia Cathepsin B precursor 0.0281 0.0432 0.1722
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Trichomonas vaginalis conserved hypothetical protein 0.0281 0.0432 0.1592
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0207 0.0248 0.0845
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1221 0.2775 0.2772
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Onchocerca volvulus Neuropeptide F receptor homolog 0.0257 0.0371 0.1311
Entamoeba histolytica hypothetical protein 0.0122 0.0034 0.0051
Schistosoma mansoni histamine h1 receptor 0.0257 0.0371 0.0366
Echinococcus multilocularis c Jun NH2 terminal kinase 0.4119 1 1
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0241 0.0332 0.0549
Echinococcus multilocularis protein kinase shaggy 0.0376 0.0668 0.0664
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0602 0.1232 0.1227
Loa Loa (eye worm) hypothetical protein 0.0122 0.0034 0.0029
Loa Loa (eye worm) TK/EPH protein kinase 0.0343 0.0587 0.0582
Echinococcus granulosus NCK adaptor protein 0.0176 0.0169 0.0164
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0257 0.0371 0.0366
Echinococcus granulosus serine:threonine protein kinase 0.0334 0.0563 0.0558
Onchocerca volvulus 0.0281 0.0432 0.1539
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0376 0.0668 0.2387
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0303 0.0487 0.083
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0587 0.1194 0.119
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0262 0.0383 0.1171
Loa Loa (eye worm) hypothetical protein 0.0257 0.0371 0.0366
Schistosoma mansoni neuropeptide f receptor 76f 0.0257 0.0371 0.0366
Schistosoma mansoni protein kinase 0.0176 0.0169 0.0164
Entamoeba histolytica cysteine protease, putative 0.066 0.1377 0.5049
Trichomonas vaginalis CMGC family protein kinase 0.0449 0.0849 0.3134
Entamoeba histolytica protein kinase, putative 0.0211 0.0256 0.0878
Echinococcus granulosus rhodopsin orphan GPCR 0.0257 0.0371 0.0366
Brugia malayi cyclin-dependent kinase 9 0.0141 0.0083 0.0065
Echinococcus multilocularis cyclin dependent kinase 5 0.0347 0.0597 0.0592
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0257 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0237 0.0322 0.0317
Schistosoma mansoni vav2 0.0245 0.0341 0.0336
Onchocerca volvulus 0.0257 0.0371 0.1311
Echinococcus granulosus N chimaerin 0.0223 0.0286 0.0281
Entamoeba histolytica casein kinase, putative 0.0293 0.0461 0.1639
Brugia malayi MH2 domain containing protein 0.0117 0.0023 0.0005
Echinococcus multilocularis serine:threonine protein kinase N2 0.0377 0.0671 0.0667
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0257 0.0371 0.0366
Brugia malayi Casein kinase II, alpha chain 0.0293 0.0461 0.0444
Echinococcus multilocularis cathepsin L 0.0281 0.0432 0.0427
Schistosoma mansoni protein kinase 0.0241 0.0332 0.0327
Schistosoma mansoni serine/threonine protein kinase 0.0425 0.079 0.0786
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.066 0.1377 0.1373
Schistosoma mansoni serine/threonine protein kinase 0.0317 0.0521 0.0516
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0469 0.0901 0.3256
Echinococcus granulosus TGF beta receptor type 1 0.0167 0.0147 0.0142
Schistosoma mansoni tyrosine kinase 0.0694 0.1461 0.1456
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0149 0.0103 0.0134
Echinococcus granulosus nervana 2 0.036 0.0628 0.0623
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0281 0.0432 0.1592
Brugia malayi casein kinase I 0.0318 0.0523 0.0506
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.066 0.1377 0.1373
Echinococcus granulosus biogenic amine 5HT receptor 0.0375 0.0665 0.0661

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 4 nM Inhibition of human factor 10a ChEMBL. 16982190
Ki (binding) = 4 nM Inhibition of human factor 10a ChEMBL. 16982190
PT (functional) = 1.3 uM Anticoagulant potency in human plasma by prothrombin time assay ChEMBL. 16982190

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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