Detailed information for compound 676497

Basic information

Technical information
  • TDR Targets ID: 676497
  • Name: 2-[(4-chlorophenyl)sulfonyl-methylamino]-N-[2 -(1-cyclohexenyl)ethyl]acetamide
  • MW: 370.894 | Formula: C17H23ClN2O3S
  • H donors: 1 H acceptors: 3 LogP: 3.09 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(CN(S(=O)(=O)c1ccc(cc1)Cl)C)NCCC1=CCCCC1
  • InChi: 1S/C17H23ClN2O3S/c1-20(24(22,23)16-9-7-15(18)8-10-16)13-17(21)19-12-11-14-5-3-2-4-6-14/h5,7-10H,2-4,6,11-13H2,1H3,(H,19,21)
  • InChiKey: LXPGXAODTAMDIW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(4-chlorophenyl)sulfonyl-methyl-amino]-N-[2-(1-cyclohexenyl)ethyl]acetamide
  • 2-[(4-chlorophenyl)sulfonyl-methyl-amino]-N-[2-(1-cyclohexenyl)ethyl]ethanamide
  • ZINC03005179

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0005 0.0168
Schistosoma mansoni hypothetical protein 0.0021 0.0025 0.0036
Schistosoma mansoni patched 1 0.0218 0.0417 0.0589
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0054 0.1979
Echinococcus multilocularis orexin receptor type 2 0.0021 0.0025 0.0025
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0025 0.0402
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0033
Entamoeba histolytica DNA topoisomerase II, putative 0.0027 0.0038 0.0203
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.1832 1
Schistosoma mansoni DNA topoisomerase II 0.0027 0.0038 0.0053
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.017 0.024
Plasmodium vivax hypothetical protein, conserved 0.0315 0.0611 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0016 0.0087
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0025 0.0036
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0025 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0035 0.0053 0.0145
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.0053 0.0075
Mycobacterium tuberculosis Probable oxidoreductase 0.037 0.0721 0.8131
Loa Loa (eye worm) TYRA-2 protein 0.0021 0.0025 0.0069
Echinococcus multilocularis g-protein coupled receptor 0.0021 0.0025 0.0025
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0025 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0109 0.3968
Giardia lamblia Kinase, PLK 0.0054 0.009 0.045
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0009 0.0332
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0013 0.0009 0.0092
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0064 0.0346
Echinococcus granulosus sterol regulatory element binding protein 0.0218 0.0417 0.0589
Echinococcus granulosus GPCR family 3 C terminal 0.0018 0.002 0.0028
Loa Loa (eye worm) hypothetical protein 0.0033 0.0048 0.0132
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0109 0.3968
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0121 0.0225 0.2524
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0013 0.001 0.0053
Schistosoma mansoni adenoreceptor 0.0021 0.0025 0.0036
Trypanosoma brucei polo-like protein kinase 0.0054 0.009 0.3297
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0009 0 0.0001
Mycobacterium ulcerans hypothetical protein 0.0013 0.001 0.0103
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0059 0.01 0.01
Echinococcus granulosus WGR domain containing protein 0.0029 0.0041 0.0058
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0051 0.0084 0.1377
Onchocerca volvulus Neuropeptide F receptor homolog 0.0021 0.0025 0.0054
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0025 0.0132
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0 0.0015
Schistosoma mansoni ap endonuclease 0.0021 0.0025 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.009 0.0491
Echinococcus granulosus serotonin transporter 0.1858 0.3682 0.5201
Plasmodium vivax SET domain protein, putative 0.006 0.0102 0.1673
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.001 0.0373
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0102 0.0102
Giardia lamblia Glutamate synthase 0.0013 0.001 0.001
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.001 0.0053
Brugia malayi Melatonin receptor type 1A 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0015
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0023 0.003 0.016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.1832 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0021 0.0025 0.0036
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0035 0.0053 0.0075
Schistosoma mansoni amine GPCR 0.0021 0.0025 0.0036
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0315 0.0611 1
Onchocerca volvulus Huntingtin homolog 0.0064 0.0112 0.0289
Leishmania major cytochrome p450-like protein 0.0013 0.0009 0.0337
Schistosoma mansoni single-minded 0.0049 0.0081 0.0114
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0016 0.0087
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0065 0.0113 0.411
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0053 0.0053
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0051 0.0084 0.3072
Loa Loa (eye worm) nuclear hormone receptor 0.0017 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Treponema pallidum thioredoxin reductase (trxB) 0.0013 0.001 0.0025
Echinococcus granulosus nmda type glutamate receptor 0.0017 0.0016 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0025 0.0036
Brugia malayi hypothetical protein 0.0017 0.0016 0.0044
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0009 0.0045
Onchocerca volvulus 0.0101 0.0184 0.0484
Brugia malayi Thioredoxin reductase 0.0146 0.0274 0.0745
Onchocerca volvulus 0.0017 0.0016 0.003
Trypanosoma cruzi cysteine proteinase, putative 0.0009 0 0.0015
Schistosoma mansoni tyrosine kinase 0.0024 0.0031 0.0043
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0021 0.0025 0.0069
Echinococcus multilocularis insulin receptor 0.0053 0.0089 0.0089
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0025 0.0036
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0051 0.0084 0.3072
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0315 0.0611 0.166
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0064 0.0173
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0036 0.0054 0.0519
Loa Loa (eye worm) hypothetical protein 0.007 0.0124 0.0336
Schistosoma mansoni hypothetical protein 0.0022 0.0028 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0025 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0045
Loa Loa (eye worm) hypothetical protein 0.0064 0.0112 0.0303
Brugia malayi steroid hormone receptor 0.0035 0.0053 0.0145
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0051 0.0084 0.3072
Schistosoma mansoni smad1 5 8 and 0.0016 0.0016 0.0022
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0025 0.0895
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0086 0.0154 0.1735
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0064 0.2323
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0225 0.2524
Brugia malayi hypothetical protein 0.0711 0.14 0.38
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0009 0.0045
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0005 0.0015
Plasmodium falciparum tyrosine kinase-like protein 0.0008 0 0.0004
Echinococcus multilocularis serotonin receptor 0.0021 0.0025 0.0025
Loa Loa (eye worm) glutathione reductase 0.0146 0.0274 0.0745
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0225 0.2459
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0016 0.0596
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0005 0.0008
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.001 0.0373
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Toxoplasma gondii cytochrome p450 superfamily protein 0.0013 0.0009 0.0151
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0113 0.1261
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0013 0.001 0.0103
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0009 0.0332
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0027 0.0038 0.0102
Trypanosoma cruzi DNA damage repair protein, putative 0.0013 0.0008 0.0306
Onchocerca volvulus 0.0014 0.0012 0.0019
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0315 0.0611 0.166
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0064 0.2323
Echinococcus granulosus 7TM GPCR rhodopsin 0.0021 0.0025 0.0036
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0015 0.0013 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0025 0.0036
Echinococcus granulosus epidermal growth factor receptor 0.0024 0.0032 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0008 0.0306
Onchocerca volvulus 0.0035 0.0053 0.013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Echinococcus multilocularis allatostatin A receptor 0.0021 0.0025 0.0025
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0016 0.0044
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0053 0.0144
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Brugia malayi Patched related family protein 10 0.0031 0.0045 0.0122
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.002 0.0023 0.0047
Schistosoma mansoni kinase 0.0027 0.0038 0.0053
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0315 0.0611 0.0863
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0109 0.3968
Echinococcus granulosus glutamate synthase 0.0013 0.001 0.0014
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0025 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0005 0.0028
Schistosoma mansoni nuclear receptor 0.0017 0.0016 0.0023
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0126 0.0178
Trypanosoma cruzi cysteine protease, putative 0.0009 0 0.0015
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0016 0.0087
Leishmania major cytochrome p450-like protein 0.0016 0.0016 0.0596
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.0016 0.0172
Onchocerca volvulus 0.0145 0.0272 0.0726
Trypanosoma cruzi DNA polymerase eta, putative 0.0093 0.017 0.6186
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0064 0.2323
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0047 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0011 0.0005 0.0075
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0013 0.001 0.0167
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0016 0.0087
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0013 0.0009 0.0104
Plasmodium vivax vivapain-2 0.0017 0.0016 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0035 0.0053 0.0053
Onchocerca volvulus 0.0031 0.0045 0.0107
Echinococcus multilocularis Tolloid protein 1 0.0021 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0016 0.0087
Echinococcus multilocularis geminin 0.0344 0.0669 0.0669
Brugia malayi Receptor family ligand binding region containing protein 0.0033 0.0048 0.0132
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0066 0.0114 0.1869
Toxoplasma gondii cathepsin CPL 0.0017 0.0016 0.0268
Echinococcus granulosus tankyrase 0.0097 0.0177 0.0249
Onchocerca volvulus 0.0121 0.0225 0.0596
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0013 0.0009 0.0104
Echinococcus granulosus Protein Wnt-04 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Schistosoma mansoni wnt-5 0.0009 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0025 0.0036
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0014 0.0012 0.0012
Onchocerca volvulus 0.0017 0.0016 0.003
Mycobacterium ulcerans dehydrogenase 0.0013 0.001 0.0103
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.002 0.0055
Schistosoma mansoni tankyrase 0.0097 0.0177 0.025
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.003 0.016
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0036 0.0054 0.1979
Schistosoma mansoni disulfide oxidoreductase 0.0013 0.001 0.0014
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0333 0.0647 0.7296
Schistosoma mansoni nuclear receptor 0.0017 0.0016 0.0023
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0064 0.0346
Brugia malayi Cytochrome P450 family protein 0.0013 0.0009 0.0025
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0016 0.0596
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0015
Onchocerca volvulus 0.0021 0.0025 0.0054
Loa Loa (eye worm) hypothetical protein 0.0121 0.0225 0.061
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0025 0.0036
Echinococcus multilocularis microtubule associated protein 2 0.3564 0.7081 0.7081
Schistosoma mansoni lamin 0.0027 0.0038 0.0054
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0018 0.002 0.0038
Brugia malayi GnHR receptor homolog 0.0021 0.0025 0.0069
Onchocerca volvulus 0.0021 0.0025 0.0054
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0054 0.0147
Echinococcus granulosus cathepsin L cysteine protease 0.0009 0 0.0001
Leishmania major NADH dehydrogenase, putative 0.0013 0.001 0.0373
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0009 0.0001 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0084 0.3072
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0315 0.0611 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0065 0.0113 0.0159
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0037 0.0057 0.0156
Onchocerca volvulus 0.0021 0.0025 0.0054
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0021 0.0025 0.0025
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0015 0.0042
Brugia malayi MH1 domain containing protein 0.0016 0.0016 0.0043
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0036 0.0054 0.0887
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Schistosoma mansoni topbp1 0.0023 0.003 0.0042
Schistosoma mansoni opsin-like receptor 0.0021 0.0025 0.0036
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0019 0.002 0.002
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0013 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Brugia malayi Glutamate receptor 2 precursor 0.0015 0.0013 0.0036
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0013 0.001 0.0028
Echinococcus multilocularis sterol regulatory element binding protein 0.0218 0.0417 0.0417
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0145 0.0272 0.0739
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0064 0.0719
Trichomonas vaginalis set domain proteins, putative 0.0474 0.0926 0.5057
Schistosoma mansoni hypothetical protein 0.0016 0.0015 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0102 0.0144
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0013 0.001 0.0014
Echinococcus granulosus cathepsin l1 0.0011 0.0005 0.0008
Loa Loa (eye worm) ctsf protein 0.0017 0.0016 0.0044
Brugia malayi nuclear receptor RXR 0.0019 0.002 0.0055
Echinococcus multilocularis nischarin 0.0234 0.045 0.045
Brugia malayi DKFZp564C0469 protein 0.0023 0.003 0.0081
Trypanosoma cruzi Aph-1 protein, putative 0.0037 0.0057 0.2087
Schistosoma mansoni glutamate synthase 0.0013 0.001 0.0014
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0453 0.0886 1
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0013 0.001 0.0373
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0083 0.1353
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0014 0.0011 0.0165
Schistosoma mansoni hypothetical protein 0.0072 0.0126 0.0178
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0021 0.0025 0.0036
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0021 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0036 0.0054 0.0601
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0025 0.0025
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0023 0.003 0.016
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0025 0.0025
Mycobacterium ulcerans DNA gyrase subunit B 0.0009 0.0001 0.0002
Onchocerca volvulus 0.0027 0.0038 0.0088
Entamoeba histolytica hypothetical protein 0.0014 0.0012 0.0064
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0016 0.0016
Brugia malayi protein C24B5.3 0.0031 0.0045 0.0122
Giardia lamblia DNA topoisomerase II 0.0026 0.0035 0.0147
Schistosoma mansoni loxhd1 0.0042 0.0066 0.0094
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0013 0.001 0.0103
Brugia malayi topoisomerase 0.0023 0.003 0.0081
Loa Loa (eye worm) Notch2 0.0009 0.0002 0.0005
Trypanosoma brucei NADH dehydrogenase 0.0013 0.001 0.0373
Onchocerca volvulus 0.0031 0.0045 0.0107
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0009 0.0001 0.0021
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0035 0.0053 0.0145
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0013 0.001 0.0103
Brugia malayi nuclear hormone receptor 0.0035 0.0053 0.0145
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0333 0.0647 0.7269
Schistosoma mansoni RAR-like nuclear receptor 0.0035 0.0053 0.0075
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0315 0.0611 0.0863
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0016 0.0023
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0023 0.003 0.3429
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0053
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Echinococcus multilocularis glutamate synthase 0.0013 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0035 0.0053 0.0145
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0025 0.0132
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0035 0.0053 0.0145
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0086 0.0154 0.1735
Brugia malayi Papain family cysteine protease containing protein 0.0009 0 0.0001
Entamoeba histolytica hypothetical protein 0.002 0.0023 0.0122
Schistosoma mansoni tyrosine kinase 0.0024 0.0032 0.0045
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0025 0.0069
Onchocerca volvulus 0.0021 0.0025 0.0054
Echinococcus multilocularis serotonin receptor 0.0021 0.0025 0.0025
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.1832 1
Treponema pallidum oxidoreductase 0.0013 0.001 0.0025
Echinococcus granulosus dna polymerase kappa 0.004 0.0064 0.009
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0016 0.0043
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0098 0.3572
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0013 0.0009 0.0092
Schistosoma mansoni neuropeptide receptor 0.0021 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0052 0.0142
Plasmodium vivax ferrodoxin reductase, putative 0.0013 0.001 0.0167
Brugia malayi Papain family cysteine protease containing protein 0.0009 0 0.0001
Echinococcus granulosus sodium and chloride dependent glycine 0.0315 0.0611 0.0863
Loa Loa (eye worm) cysteine protease 0.0017 0.0016 0.0044
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0016 0.0016
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0035 0.0053 0.0075
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0035 0.0053 0.0145
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0009 0.0001 0.0012
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0051 0.0084 0.3072
Echinococcus granulosus g protein coupled receptor 0.0021 0.0025 0.0036
Onchocerca volvulus Protein patched homolog 0.0031 0.0045 0.0107
Echinococcus granulosus thioredoxin glutathione reductase 0.0146 0.0274 0.0387
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.001 0.0053
Giardia lamblia DINP protein human, muc B family 0.004 0.0064 0.0303
Onchocerca volvulus 0.0021 0.0025 0.0054
Plasmodium falciparum thioredoxin reductase 0.0051 0.0084 0.1377
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0031 0.0044 0.0501
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0016 0.0023
Brugia malayi serine/threonine-protein kinase plk-2 0.0054 0.009 0.0245
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0122
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.002
Brugia malayi hypothetical protein 0.0164 0.031 0.0841
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Onchocerca volvulus Huntingtin homolog 0.0064 0.0112 0.0289
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0051 0.0084 0.3072
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0009 0.0045
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0036 0.0054 0.0612
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0015 0.0042
Brugia malayi nuclear receptor NHR-67 0.0017 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Schistosoma mansoni steroid hormone receptor ad4bp 0.0035 0.0053 0.0075
Plasmodium falciparum ferrodoxin reductase-like protein 0.0013 0.001 0.0167
Entamoeba histolytica hypothetical protein 0.002 0.0023 0.0122
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0013 0.001 0.0373
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Onchocerca volvulus 0.0021 0.0025 0.0054
Brugia malayi cytochrome P450 0.0013 0.0009 0.0025
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0033 0.0048 0.0132
Entamoeba histolytica hypothetical protein 0.0014 0.0012 0.0065
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0218 0.0417 0.1133
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.001 0.001
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0021 0.0025 0.0036
Echinococcus granulosus smad 0.0016 0.0016 0.0022
Entamoeba histolytica hypothetical protein 0.002 0.0023 0.0122
Schistosoma mansoni wnt related 0.0009 0.0001 0.0001
Brugia malayi G protein-coupled receptor 0.0021 0.0025 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0064 0.2323
Brugia malayi hypothetical protein 0.0019 0.002 0.0055
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0055 0.0614
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0013 0.0009 0.0104
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Loa Loa (eye worm) hypothetical protein 0.0218 0.0417 0.1133
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.0054 0.0147
Echinococcus granulosus poly (ADP ribose) polymerase 0.0014 0.0012 0.0017
Brugia malayi Patched related family protein 12 0.0031 0.0045 0.0122
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Schistosoma mansoni hypothetical protein 0.0016 0.0015 0.0022
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0035 0.0053 0.0053
Echinococcus granulosus ecdysone induced protein 78C 0.0035 0.0053 0.0075
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.001 0.0053
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Schistosoma mansoni smad 0.0016 0.0016 0.0022
Schistosoma mansoni biogenic amine receptor 0.0021 0.0025 0.0036
Trypanosoma brucei DNA damage repair protein, putative 0.0013 0.0008 0.0306
Onchocerca volvulus 0.1858 0.3682 1
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0083 0.3017
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0015
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0013 0.0009 0.0092
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0069
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0016 0.0087
Entamoeba histolytica acyl-CoA synthetase, putative 0.0121 0.0225 0.1224
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0009 0.0319
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0021 0.0025 0.0036
Echinococcus multilocularis smad 0.0016 0.0016 0.0016
Brugia malayi hypothetical protein 0.0031 0.0045 0.0122
Plasmodium vivax vivapain-2 0.0017 0.0016 0.0268
Brugia malayi wnt family protein 0.0009 0.0001 0.0002
Entamoeba histolytica hypothetical protein 0.0072 0.0126 0.0686
Treponema pallidum fructose-bisphosphate aldolase 0.0928 0.1832 0.4972
Trichomonas vaginalis CAMK family protein kinase 0.0027 0.0036 0.0197
Toxoplasma gondii hypothetical protein 0.0031 0.0045 0.0732
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.017 0.0462
Schistosoma mansoni tyrosine kinase 0.0053 0.0089 0.0126
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0145
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0013 0.0009 0.0104
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Loa Loa (eye worm) glutamate receptor 0.0044 0.0071 0.0193
Loa Loa (eye worm) hypothetical protein 0.0315 0.0611 0.166
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0102 0.0144
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.037 0.0721 0.8131
Plasmodium vivax amine transporter, putative 0.0315 0.0611 1
Loa Loa (eye worm) hypothetical protein 0.009 0.0164 0.0444
Brugia malayi hypothetical protein 0.0021 0.0025 0.0069
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0013 0.0009 0.0104
Schistosoma mansoni glutamate receptor kainate 0.0015 0.0013 0.0019
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0315 0.0611 0.166
Brugia malayi metabotropic glutamate receptor type 2 0.0059 0.01 0.0271
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0009 0.0012
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0015 0.0022
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0016 0.0016
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0021 0.0025 0.0036
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0055 0.0151
Brugia malayi Cathepsin L-like precursor 0.0017 0.0016 0.0044
Brugia malayi G-protein coupled receptor 0.0021 0.0025 0.0069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0102 0.0144
Leishmania major hypothetical protein, conserved 0.005 0.0083 0.3017
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0051 0.0084 0.1362
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0018 0.002 0.0053
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0013 0.001 0.0053
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0315 0.0611 0.0863
Loa Loa (eye worm) hypothetical protein 0.0051 0.0084 0.0229
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0126 0.0126
Schistosoma mansoni amine GPCR 0.0021 0.0025 0.0036
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0025 0.0036
Echinococcus multilocularis Niemann Pick C1 protein 0.0508 0.0994 0.0994
Echinococcus multilocularis protein dispatched 1 0.0249 0.0478 0.0478
Schistosoma mansoni amine GPCR 0.0021 0.0025 0.0036
Onchocerca volvulus 0.0474 0.0927 0.2505
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0024
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0025 0.0036
Plasmodium falciparum thioredoxin reductase 0.0146 0.0274 0.4485
Schistosoma mansoni glutamate synthase 0.0013 0.001 0.0014
Leishmania major cytochrome p450-like protein 0.0013 0.0009 0.0337
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0315 0.0611 0.0863
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0013 0.0009 0.0092
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0013 0.0009 0.0092
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0017 0.0016 0.003
Brugia malayi PAS domain containing protein 0.0049 0.0081 0.0219
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0017 0.0016 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0064 0.2323
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0017 0.0016 0.0023
Plasmodium vivax vivapain-1 0.0009 0 0.0007
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0035 0.0053 0.0075
Onchocerca volvulus 0.0042 0.0066 0.0165
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0013 0.001 0.0017
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0055
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0016 0.0023
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0012 0.0008 0.0275
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0083 0.1353
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0013 0.001 0.0167
Schistosoma mansoni hypothetical protein 0.021 0.0402 0.0567
Brugia malayi hypothetical protein 0.0017 0.0016 0.0044
Onchocerca volvulus 0.0021 0.0025 0.0054
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0453 0.0886 1
Schistosoma mansoni neuropeptide receptor 0.0021 0.0025 0.0036
Trichomonas vaginalis apoptosis inducing factor, putative 0.0013 0.001 0.0053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0016 0.0087
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0013 0.0009 0.0337
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.009 0.0491
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0016 0.0023
Echinococcus granulosus Nuclear hormone receptor HR96 0.0017 0.0016 0.0023
Schistosoma mansoni rab6-interacting 0.0042 0.0066 0.0094
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0009 0.0001 0.0001
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0013 0.001 0.0115
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0054 0.1979
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0054 0.009 0.0245
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0036 0.0054 0.0601
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0145
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.001 0.0014
Entamoeba histolytica hypothetical protein 0.002 0.0023 0.0122
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Brugia malayi hypoxia-induced factor 1 0.0151 0.0284 0.0772
Brugia malayi hypothetical protein 0.005 0.0083 0.0225
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0011 0.0005 0.0402
Echinococcus granulosus gamma secretase subunit aph 1 0.0095 0.0173 0.0244
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0069
Echinococcus granulosus glutamate receptor 2 0.0029 0.0042 0.006
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0102 0.1673
Onchocerca volvulus 0.0315 0.0611 0.1648
Echinococcus granulosus neuropeptide s receptor 0.0488 0.0956 0.1349
Echinococcus granulosus tachykinin peptides receptor 99D 0.0021 0.0025 0.0036
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0064 0.2323
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0081
Schistosoma mansoni tyrosine kinase 0.0024 0.0031 0.0043
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0013 0.0034
Echinococcus multilocularis WNT 0.0009 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0018 0.002 0.0028
Leishmania major DNA repair protein, putative 0.0012 0.0008 0.0275
Leishmania major acetyl-CoA synthetase, putative 0.0036 0.0054 0.1979
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.1858 0.3682 1
Echinococcus multilocularis tumor protein p63 0.0687 0.1351 0.1351
Loa Loa (eye worm) oxidoreductase 0.0036 0.0054 0.0147
Loa Loa (eye worm) hypothetical protein 0.0315 0.0611 0.166
Echinococcus granulosus thyroid hormone receptor alpha 0.0017 0.0016 0.0023
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Schistosoma mansoni thyroid hormone receptor 0.0035 0.0053 0.0075
Brugia malayi Doublecortin family protein 0.0042 0.0066 0.018
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0017 0.0016 0.0023
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Toxoplasma gondii NADPH-glutathione reductase 0.0051 0.0084 0.1377
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Loa Loa (eye worm) patched family protein 0.0031 0.0045 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0045
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0013 0.0009 0.0092
Entamoeba histolytica hypothetical protein 0.0072 0.0126 0.0686
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0009 0.0332
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0005 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0054 0.0601
Plasmodium falciparum DNA repair protein REV1, putative 0.0013 0.0008 0.0137
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0315 0.0611 0.166
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Onchocerca volvulus 0.0017 0.0016 0.003
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0084 0.0229
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0013 0.001 0.0167
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0036 0.0054 0.0519
Treponema pallidum DNA ligase (lig) 0.0023 0.003 0.0078
Echinococcus granulosus lamin 0.0027 0.0038 0.0054
Brugia malayi Patched protein homolog 1 0.0031 0.0045 0.0122
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0066 0.0094
Schistosoma mansoni sulfide quinone reductase 0.0013 0.001 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0016 0.0087
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0017 0.0016 0.0016
Onchocerca volvulus 0.0027 0.0038 0.0088
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0013 0.001 0.001
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0083 0.1353
Entamoeba histolytica acyl-coA synthetase, putative 0.0121 0.0225 0.1224
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0064 0.0707
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.001 0.0373
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0054 0.0147
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0025 0.0036
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0035 0.0053 0.0075
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0025 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0109 0.3968
Echinococcus granulosus cysteine protease 0.0009 0 0.0001
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0009 0 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0016 0.0087
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0051 0.0084 0.1377
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0054 0.0147
Onchocerca volvulus 0.0023 0.003 0.0066
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0016 0.0022
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0042 0.0042
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0036 0.0054 0.0612
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0013 0.0009 0.0337
Onchocerca volvulus Bile acid receptor homolog 0.0035 0.0053 0.013
Chlamydia trachomatis DNA ligase 0.0023 0.003 0.0469
Echinococcus granulosus receptor type guanylyl cyclase 0.0015 0.0013 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0122
Trypanosoma cruzi NADH dehydrogenase, putative 0.0013 0.001 0.0373
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0023 0.003 0.0239
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0055 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0122
Loa Loa (eye worm) tnks protein 0.0089 0.0161 0.0437
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0038 0.0103
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0333 0.0647 0.7296
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.0027
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0025 0.0036
Trypanosoma cruzi Aph-1 protein, putative 0.0037 0.0057 0.2087
Schistosoma mansoni metabotropic glutamate receptor 0.037 0.0721 0.1018
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0064 0.2323
Echinococcus multilocularis epidermal growth factor receptor 0.0024 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0055
Plasmodium falciparum cysteine proteinase falcipain 1 0.0009 0 0.0007
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0016 0.0268
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0121 0.0225 0.2534
Onchocerca volvulus 0.0036 0.0054 0.0133
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0051 0.0084 0.0229
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0066 0.0094
Brugia malayi Receptor family ligand binding region containing protein 0.0015 0.0013 0.0036
Echinococcus granulosus hypothetical protein 0.0021 0.0025 0.0036
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0086 0.0154 0.1735
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0064 0.2323
Schistosoma mansoni tyrosine kinase 0.0024 0.0032 0.0045
Echinococcus granulosus geminin 0.0344 0.0669 0.0945
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0016 0.0016
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0036 0.0054 0.0601
Loa Loa (eye worm) serotonin transporter b 0.1858 0.3682 1
Brugia malayi hypothetical protein 0.0021 0.0025 0.0069
Brugia malayi neuropeptide F receptor 0.0021 0.0025 0.0069
Echinococcus multilocularis glutamate receptor 2 0.0022 0.0027 0.0027
Trypanosoma cruzi DNA topoisomerase II, putative 0.0024 0.0032 0.1172
Loa Loa (eye worm) hypothetical protein 0.0229 0.0439 0.1193
Chlamydia trachomatis DNA gyrase subunit B 0.0009 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0033
Toxoplasma gondii patched family protein 0.0031 0.0045 0.0732
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0027 0.0038 0.0102
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0102 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0039 0.1415
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0013 0.001 0.0373
Loa Loa (eye worm) hypothetical protein 0.0315 0.0611 0.166
Echinococcus granulosus RUN 0.0042 0.0066 0.0094
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0025 0.0067
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0109 0.3968
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0064 0.0064
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0051 0.1873
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0036 0.0054 0.0601
Echinococcus multilocularis neuropeptide receptor A26 0.0488 0.0956 0.0956
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.017 0.0462
Brugia malayi Pre-SET motif family protein 0.006 0.0102 0.0278
Trypanosoma cruzi DNA damage repair protein, putative 0.0013 0.0008 0.0306
Schistosoma mansoni Smad4 0.0016 0.0016 0.0022
Schistosoma mansoni hypothetical protein 0.0013 0.001 0.0014
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0036 0.0054 0.0147
Schistosoma mansoni hypothetical protein 0.0016 0.0015 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.003 0.016
Leishmania major protein kinase, putative 0.0013 0.0009 0.0332
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0036 0.0054 0.0601
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0064 0.2323
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0016 0.0268
Brugia malayi nuclear hormone receptor 0.0017 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.009 0.0164 0.0444
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0035 0.0053 0.0145
Schistosoma mansoni smad1 5 8 and 0.0016 0.0016 0.0022
Toxoplasma gondii propionate-CoA ligase 0.0036 0.0054 0.0887
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Loa Loa (eye worm) nuclear receptor NHR-67 0.0017 0.0016 0.0044
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0013 0.0009 0.0092
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0021 0.0025 0.0036
Echinococcus granulosus serotonin receptor 0.0021 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Mycobacterium ulcerans hypothetical protein 0.0121 0.0225 0.2524
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0064 0.0719
Echinococcus granulosus g protein coupled receptor 0.0021 0.0025 0.0036
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0021 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0013 0.0009 0.0013
Schistosoma mansoni ATP-binding cassette transporter 0.0015 0.0013 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0064 0.2323
Brugia malayi Dopamine receptor protein 2 0.0021 0.0025 0.0069
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0016 0.0044
Schistosoma mansoni intermediate filament proteins 0.0027 0.0038 0.0054
Echinococcus multilocularis WNT 0.0009 0.0001 0.0001
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0009 0.0045
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0025 0.0025
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0054 0.1979
Toxoplasma gondii selenide, water dikinase 0.0013 0.001 0.0167
Echinococcus granulosus nmda type glutamate receptor 0.0014 0.0012 0.0017
Schistosoma mansoni smad1 5 8 and 0.0016 0.0016 0.0022
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0084 0.0229
Echinococcus granulosus Protein Wnt-111 0.0009 0.0001 0.0001
Trypanosoma cruzi NADH dehydrogenase, putative 0.0013 0.001 0.0373
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0013 0.001 0.1078
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0013 0.0009 0.0092
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0024
Schistosoma mansoni tyrosine kinase 0.0024 0.0031 0.0043
Schistosoma mansoni hypothetical protein 0.0021 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0042 0.006
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0036 0.0054 0.0601
Schistosoma mansoni sodium/chloride dependent transporter 0.0316 0.0612 0.0864
Schistosoma mansoni rab6-interacting 0.0042 0.0066 0.0094
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Echinococcus granulosus Protein patched homolog 1 0.0218 0.0417 0.0589
Schistosoma mansoni growth hormone secretagogue receptor 0.0021 0.0025 0.0036
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0315 0.0611 0.0863
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0013 0.0008 0.0137
Plasmodium vivax glutathione reductase, putative 0.0146 0.0274 0.4485
Onchocerca volvulus 0.0036 0.0054 0.0133
Brugia malayi hypothetical protein 0.0021 0.0025 0.0069
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0013 0.001 0.0017
Schistosoma mansoni hypothetical protein 0.0035 0.0052 0.0074
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0013 0.001 0.0373
Loa Loa (eye worm) cytochrome P450 0.0013 0.0009 0.0025
Leishmania major cathepsin L-like protease 0.0017 0.0016 0.0597
Echinococcus multilocularis expressed conserved protein 0.0477 0.0933 0.0933
Brugia malayi neuropeptide F receptor 0.0021 0.0025 0.0069
Onchocerca volvulus Protein ultraspiracle homolog 0.0035 0.0053 0.013
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0016 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0315 0.0611 0.0611
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0084 0.3072
Onchocerca volvulus 0.0021 0.0025 0.0054
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0015 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0122
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0129 0.024 0.3921
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0315 0.0611 0.0863
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0013 0.001 0.0028
Loa Loa (eye worm) hypothetical protein 0.0121 0.0225 0.061
Echinococcus multilocularis protein Wnt 2 0.0009 0.0001 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0054 0.0601
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0035 0.0053 0.0145
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0016 0.0044
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0024 0.0032 0.1172
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0021 0.0025 0.0025
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0013 0.0009 0.0092
Loa Loa (eye worm) patched family protein 0.0031 0.0045 0.0122
Schistosoma mansoni acetyl-CoA synthetase 0.0036 0.0054 0.0077
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0053 0.0075
Loa Loa (eye worm) melatonin receptor type 1A 0.0021 0.0025 0.0069
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0013 0.0009 0.0092
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0009 0.0002 0.0059
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0025 0.0025
Entamoeba histolytica cysteine protease, putative 0.0017 0.0016 0.0087
Toxoplasma gondii patched family protein 0.0031 0.0045 0.0732
Brugia malayi hypothetical protein 0.0031 0.0045 0.0122
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0035 0.0053 0.0075
Echinococcus multilocularis GPCR, family 3, C terminal 0.0018 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0021 0.0025 0.0036
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0054 0.1979
Trichomonas vaginalis glutathione reductase, putative 0.0051 0.0084 0.0458
Echinococcus multilocularis protein patched 0.0218 0.0417 0.0417
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0059 0.01 0.0271
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0064 0.0707
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0013 0.0009 0.0104
Echinococcus multilocularis wingless type MMTV integration site family 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0015 0.0013 0.0021
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0025 0.0064
Brugia malayi Guanylyl cyclase protein 23 0.0015 0.0013 0.0036
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0021 0.0025 0.0069
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0016 0.003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0025 0.0036
Brugia malayi G-protein coupled receptor 0.0021 0.0025 0.0069
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.017 0.024
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0225 0.2459
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Loa Loa (eye worm) CWN-2 protein 0.0009 0.0001 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0035 0.0053 0.0145
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0064 0.2323
Toxoplasma gondii patched family protein 0.0031 0.0045 0.0732
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0013 0.001 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0025 0.0025
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0515 0.101 0.1426
Brugia malayi Cathepsin L-like precursor 0.0017 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0054
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0025 0.0036
Echinococcus multilocularis neuropeptide FF receptor 2 0.0021 0.0025 0.0025
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.0054 0.0147
Toxoplasma gondii exonuclease III APE 0.0021 0.0025 0.0402
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0315 0.0611 0.0863
Leishmania major mitochondrial DNA topoisomerase II 0.0021 0.0026 0.0949
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0064 0.0173
Giardia lamblia NADH oxidase lateral transfer candidate 0.0051 0.0084 0.0416
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0315 0.0611 0.166
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.001 0.0014
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0315 0.0611 1
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0036 0.0054 0.0887
Plasmodium vivax unspecified product 0.0009 0 0.0007
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.001 0.001
Toxoplasma gondii ATPase, AAA family protein 0.0023 0.003 0.0486
Loa Loa (eye worm) hypothetical protein 0.0029 0.0041 0.0112
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0013 0.001 0.0103
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0028 0.004
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0064 0.011 0.4027
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.0008 0.0306
Brugia malayi Steroid receptor seven-up type 2 0.0035 0.0053 0.0145
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0016 0.0087
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.017 0.024
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0021 0.0026 0.0069
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0025 0.0025
Entamoeba histolytica acyl-CoA synthetase, putative 0.0121 0.0225 0.1224
Plasmodium falciparum glutathione reductase 0.0146 0.0274 0.4485
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.001 0.0167
Loa Loa (eye worm) MH2 domain-containing protein 0.0239 0.0459 0.1247
Schistosoma mansoni glutamate receptor NMDA 0.0047 0.0077 0.0108
Schistosoma mansoni cytochrome P450 0.0013 0.0009 0.0013
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0113 0.0306
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.003 0.1084
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0045
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0037 0.0057 0.0156
Entamoeba histolytica serine/threonine protein kinase, putative 0.0054 0.009 0.0491
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0009 0.0024
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0013 0.0009 0.0092
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0016 0.0016
Echinococcus granulosus replication factor c subunit 1 0.0023 0.003 0.0042
Schistosoma mansoni rotamase 0.0035 0.0053 0.0075
Brugia malayi hypothetical protein 0.0021 0.0025 0.0069
Trichomonas vaginalis CAMK family protein kinase 0.0027 0.0036 0.0197
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0095 0.0173 0.0469
Brugia malayi ImpB/MucB/SamB family protein 0.0093 0.017 0.0461
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0013 0.0009 0.0104
Loa Loa (eye worm) hypothetical protein 0.0093 0.017 0.0461
Onchocerca volvulus 0.0017 0.0016 0.003
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0013 0.0009 0.0104
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0013 0.001 0.0053
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0021 0.0026 0.0036
Onchocerca volvulus 0.0021 0.0025 0.0054
Trypanosoma brucei poly(adp-ribose) polymerase 0.0064 0.011 0.4027
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0333 0.0647 0.7296
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0051 0.1873
Schistosoma mansoni ap endonuclease 0.0021 0.0025 0.0035
Brugia malayi hypothetical protein 0.0021 0.0025 0.0069
Onchocerca volvulus DNA ligase 3 homolog 0.0012 0.0008 0.0006
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0066 0.018
Echinococcus granulosus Protein Wnt-11b 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0081
Echinococcus granulosus Protein Wnt-5 0.0009 0.0001 0.0001
Mycobacterium ulcerans NADH dehydrogenase 0.0013 0.001 0.0103
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0053 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0023 0.003 0.1084
Echinococcus multilocularis laminin 0.0021 0.0026 0.0026
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0051 0.0084 0.1377
Toxoplasma gondii calcium binding egf domain-containing protein 0.0021 0.0026 0.0419
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.017 0.017
Echinococcus multilocularis neuropeptide s receptor 0.0488 0.0956 0.0956
Echinococcus granulosus fmrfamide receptor 0.0021 0.0025 0.0036
Brugia malayi hypothetical protein 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Plasmodium vivax patched family protein, putative 0.0031 0.0045 0.0732
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0035 0.0053 0.0145
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0013 0.001 0.1078
Loa Loa (eye worm) Wnt2 protein 0.0009 0.0001 0.0002
Brugia malayi MH1 domain containing protein 0.0009 0.0001 0.0004
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0013 0.0009 0.0104
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0035 0.0053 0.0075
Brugia malayi MH2 domain containing protein 0.0239 0.0459 0.1247
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0315 0.0611 0.166
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0064 0.2323
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.017 0.024
Loa Loa (eye worm) patched family protein 0.0031 0.0045 0.0122
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.009 0.0128
Schistosoma mansoni polycystin 1-related 0.0042 0.0066 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0035 0.0053 0.013
Schistosoma mansoni tyrosine kinase 0.0015 0.0013 0.0019
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0053 0.0089 0.0089
Schistosoma mansoni sodium/chloride dependent transporter 0.0315 0.0611 0.0863
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0064 0.2323
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0146 0.0274 0.3094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0054 0.0612
Brugia malayi WGR domain containing protein 0.0105 0.0193 0.0525
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0025 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0025 0.0036
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Trypanosoma cruzi DNA repair protein, putative 0.0012 0.0008 0.0275
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0051 0.0084 0.3072
Echinococcus multilocularis glutamate receptor 2 0.0029 0.0042 0.0042
Brugia malayi Cytochrome P450 family protein 0.0016 0.0016 0.0044
Echinococcus multilocularis cysteine protease 0.0017 0.0016 0.0016
Brugia malayi protein C24B5.3 0.0031 0.0045 0.0122
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0145
Echinococcus granulosus allatostatin A receptor 0.0021 0.0025 0.0036
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0042 0.006
Brugia malayi Wnt-2 protein precursor 0.0009 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0025 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0025 0.0025
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0.0013 0.0036
Echinococcus multilocularis Smad4 0.0016 0.0016 0.0016
Trypanosoma cruzi polo-like protein kinase, putative 0.0054 0.009 0.3297
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Brugia malayi hypothetical protein 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0013 0.0009 0.0104
Schistosoma mansoni hypothetical protein 0.021 0.0402 0.0567
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0508 0.0994 0.5426
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0016 0.0043
Trypanosoma brucei unspecified product 0.0028 0.0039 0.1415
Echinococcus granulosus nibrin 0.0023 0.003 0.0042
Trichomonas vaginalis antibiotic synthetase, putative 0.0036 0.0054 0.0294
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0021 0.0025 0.0036
Toxoplasma gondii calcium binding egf domain-containing protein 0.0021 0.0026 0.0419
Echinococcus granulosus expressed conserved protein 0.0477 0.0933 0.1317
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0024 0.0032 0.0045
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Brugia malayi putative neuropeptide receptor NPR1 0.0021 0.0025 0.0069
Plasmodium vivax acyl-CoA synthetase, putative 0.009 0.0164 0.2676
Echinococcus granulosus nischarin 0.0234 0.045 0.0636
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0113 0.0113
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.001 0.0053
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Echinococcus multilocularis RUN 0.0042 0.0066 0.0066
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0051 0.0084 0.0119
Loa Loa (eye worm) hypothetical protein 0.0035 0.0052 0.0142
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0121 0.0225 0.2524
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0035 0.0053 0.0053
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0225 0.819
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0035 0.0053 0.0145
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0018 0.002 0.0053
Trichomonas vaginalis mercuric reductase, putative 0.0051 0.0084 0.0458
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0036 0.0054 0.0612
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0021 0.0025 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0 0.0015
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0013 0.001 0.0115
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0036 0.0054 0.0612
Brugia malayi Nuclear hormone receptor E75 0.0017 0.0016 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0035 0.0053 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0109 0.3968
Plasmodium vivax DNA gyrase subunit B, putative 0.0009 0.0001 0.0021
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0051 0.0084 0.0939
Leishmania major DNA polymerase kappa, putative 0.0013 0.0008 0.0306
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0013 0.0009 0.0092
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0034 0.0051 0.0051
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0025 0.0036
Brugia malayi nuclear receptor NHR-88 0.0035 0.0053 0.0145
Schistosoma mansoni wnt related 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0147
Giardia lamblia Thioredoxin reductase 0.0013 0.001 0.001
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0054 0.0612
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Trypanosoma brucei unspecified product 0.0028 0.0039 0.1415
Brugia malayi hypothetical protein 0.0064 0.0112 0.0303
Leishmania major DNA polymerase eta, putative 0.0093 0.017 0.6186
Brugia malayi nuclear receptor NHR-88 0.0017 0.0016 0.0044
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0315 0.0611 0.0863
Brugia malayi Protein kinase domain containing protein 0.0053 0.0089 0.0242
Schistosoma mansoni protein kinase 0.0015 0.0013 0.0019
Toxoplasma gondii patched family protein 0.0031 0.0045 0.0732
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0508 0.0994 0.2699
Schistosoma mansoni gamma-secretase subunit aph-1 0.0095 0.0173 0.0244
Loa Loa (eye worm) thioredoxin reductase 0.0146 0.0274 0.0745
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0121 0.0225 0.2524
Brugia malayi Tnks protein 0.0096 0.0175 0.0476
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0021 0.0025 0.0036
Schistosoma mansoni metabotropic glutamate receptor 0.0014 0.0012 0.0017
Chlamydia trachomatis thioredoxin reductase 0.0013 0.001 0.015
Entamoeba histolytica zinc finger protein, putative 0.002 0.0023 0.0122
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.003 0.016
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0013 0.0009 0.0092
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.1832 1
Leishmania major cathepsin L-like protease 0.0063 0.0109 0.3968
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0064 0.2323
Entamoeba histolytica hypothetical protein 0.0023 0.003 0.016
Brugia malayi Niemann-Pick C1 protein precursor 0.0508 0.0994 0.2699
Echinococcus granulosus Smad4 0.0016 0.0016 0.0022
Brugia malayi nuclear hormone receptor family member nhr-6 0.0017 0.0016 0.0044
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.001 0.0373
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0021 0.0025 0.0069
Loa Loa (eye worm) glutamate receptor 0.0033 0.0048 0.0132
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0036 0.0054 0.0601
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0029 0.0042 0.0042
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0009 0.0332
Brugia malayi larval opioid receptor 0.0021 0.0025 0.0069
Leishmania major cathepsin L-like protease 0.0017 0.0016 0.0597
Onchocerca volvulus 0.0021 0.0025 0.0054
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0928 0.1832 1
Leishmania major trypanothione reductase 0.0146 0.0274 1
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0013 0.001 0.0115
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0051 0.0278
Loa Loa (eye worm) hypothetical protein 0.009 0.0164 0.0444
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0064 0.009
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0013 0.001 0.0014
Schistosoma mansoni hypothetical protein 0.0021 0.0025 0.0036
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0016 0.0023
Leishmania major protein kinase, putative 0.0013 0.0009 0.0332
Echinococcus multilocularis fibrillin 1 0.0021 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.006 0.0102 0.0278
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0013 0.0009 0.0104
Onchocerca volvulus Tankyrase homolog 0.0088 0.0158 0.0416
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0105 0.0193 0.1054
Onchocerca volvulus 0.0315 0.0611 0.1648
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0225 0.061
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0185 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0122
Leishmania major cathepsin L-like protease 0.0017 0.0016 0.0597
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0051 0.0084 0.0939
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0017 0.0016 0.0044
Leishmania major DNA topoisomerase ii 0.0024 0.0032 0.1172
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0024
Echinococcus granulosus laminin 0.0021 0.0026 0.0036
Echinococcus multilocularis sodium and chloride dependent glycine 0.0315 0.0611 0.0611
Trypanosoma brucei DNA repair protein, putative 0.0012 0.0008 0.0275
Loa Loa (eye worm) transcription factor SMAD2 0.0239 0.0459 0.1247
Trichomonas vaginalis rotamase, putative 0.0034 0.0051 0.0278
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0054 0.0601
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.002 0.0055
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0017 0.0016 0.0023
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0035 0.0053 0.0075
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0064 0.009
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0036 0.0054 0.0612
Loa Loa (eye worm) glutamate receptor 1 0.0015 0.0013 0.0036
Mycobacterium ulcerans glutamate synthase subunit beta 0.0013 0.001 0.0103
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0049 0.0082 0.0222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Brugia malayi wnt family protein 0.0009 0.0001 0.0002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0051 0.0084 1
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0109 0.3968
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0005 0.0168
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0044 0.0071 0.01
Plasmodium falciparum replication factor C subunit 1, putative 0.0023 0.003 0.0486
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0051 0.1873
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0064 0.2323
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0225 0.819
Trichomonas vaginalis glutamate synthase, putative 0.0013 0.001 0.0053
Brugia malayi glutamate synthase 0.0013 0.001 0.0028
Brugia malayi cathepsin L-like precursor 0.0011 0.0005 0.0015
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0013 0.001 0.0167
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0025 0.0036
Plasmodium falciparum acyl-CoA synthetase 0.009 0.0164 0.2676
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0035 0.0053 0.0145
Echinococcus granulosus cathepsin L 0.0009 0 0.0001
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0013 0.001 0.0053
Onchocerca volvulus Poor gastrulation protein homolog 0.0018 0.002 0.0038
Brugia malayi Wnt-4 protein precursor 0.0009 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0145
Entamoeba histolytica hypothetical protein 0.0072 0.0126 0.0686
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0098 0.0138
Toxoplasma gondii DNA topoisomerase 2, putative 0.0027 0.0038 0.0615
Echinococcus granulosus poly (ADP ribose) polymerase 0.0014 0.0012 0.0017
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0054 0.0601
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0021 0.0025 0.0025
Brugia malayi Myosin head containing protein 0.0031 0.0045 0.0122
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0013 0.0009 0.0092
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0013 0.001 0.0017
Schistosoma mansoni hypothetical protein 0.0344 0.0669 0.0945
Onchocerca volvulus 0.0017 0.0016 0.003
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0042 0.0042
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0054 0.0601
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0021 0.0025 0.0069
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0019 0.002 0.0029
Schistosoma mansoni tyrosine kinase 0.0024 0.0032 0.0045
Plasmodium falciparum amino acid transporter, putative 0.0315 0.0611 1
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0013 0.0009 0.0092
Trypanosoma cruzi DNA topoisomerase II, putative 0.0024 0.0032 0.1172
Schistosoma mansoni cellular tumor antigen P53 0.0101 0.0184 0.0259
Schistosoma mansoni hypothetical protein 0.0145 0.0272 0.0385
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.0008 0.0306
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0225 0.2524
Echinococcus granulosus tumor protein p63 0.0687 0.1351 0.1908
Loa Loa (eye worm) solute carrier family 6 member 4 0.1858 0.3682 1
Echinococcus granulosus neuropeptide receptor A26 0.0488 0.0956 0.1349
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0013 0.0009 0.0104
Echinococcus multilocularis nmda type glutamate receptor 0.0014 0.0012 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0084 0.3072
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.037 0.0721 0.8112
Brugia malayi Smad1 0.0016 0.0016 0.0043
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0036 0.0054 0.0077
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0013 0.001 0.0053
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0055
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Loa Loa (eye worm) patched family protein 0.0031 0.0045 0.0122
Onchocerca volvulus 0.0017 0.0016 0.003
Brugia malayi Cytochrome P450 family protein 0.0016 0.0016 0.0044
Brugia malayi hypothetical protein 0.0023 0.003 0.0081
Brugia malayi glutathione reductase 0.0146 0.0274 0.0745
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0066 0.0094
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0013 0.0009 0.0092
Schistosoma mansoni neuropeptide receptor 0.0021 0.0025 0.0036
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0017 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.021 0.0402 0.0567
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0081
Plasmodium vivax acetyl-CoA synthetase, putative 0.0036 0.0054 0.0887
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0033 0.0048 0.0132
Brugia malayi MH2 domain containing protein 0.0016 0.0016 0.0043
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0113 0.0159
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Leishmania major cathepsin L-like protease 0.0017 0.0016 0.0597
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0008 0.0306
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0017 0.0016 0.0044
Schistosoma mansoni opsin-like receptor 0.0021 0.0025 0.0036
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0021 0.0025 0.0054
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0055
Onchocerca volvulus 0.0021 0.0025 0.0054
Brugia malayi ORL1-like opioid receptor 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0081
Echinococcus multilocularis musashi 0.0027 0.0038 0.0038
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.1832 1
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0053 0.0145
Echinococcus granulosus alpha 1A adrenergic receptor 0.0021 0.0025 0.0036
Trypanosoma brucei unspecified product 0.004 0.0064 0.2323
Toxoplasma gondii hypothetical protein 0.0315 0.0611 1
Trypanosoma cruzi extracellular receptor, putative 0.0014 0.0012 0.0449
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0023
Brugia malayi photoreceptor-specific nuclear receptor 0.0035 0.0053 0.0145
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0126 0.0178
Loa Loa (eye worm) hypothetical protein 0.009 0.0164 0.0444
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0021 0.0025 0.0025
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0021 0.0025 0.0036
Leishmania major cathepsin L-like protease 0.0063 0.0109 0.3968
Plasmodium falciparum lipid/sterol:H+ symporter 0.0031 0.0045 0.0732
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0042 0.006
Echinococcus granulosus metabotropic glutamate receptor 5 0.0059 0.01 0.0141
Onchocerca volvulus 0.0031 0.0045 0.0107
Brugia malayi WGR domain containing protein 0.0064 0.011 0.03
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0035 0.0053 0.0145
Echinococcus multilocularis nibrin 0.0023 0.003 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.009 0.0491
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0021 0.0025 0.0025
Plasmodium vivax replication factor C subunit 1, putative 0.0023 0.003 0.0486
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0009 0.0009
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0023 0.003 0.016
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0081
Brugia malayi MH2 domain containing protein 0.0016 0.0016 0.0043
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0036 0.0054 0.0519
Brugia malayi Dopamine receptor 0.0021 0.0025 0.0069
Brugia malayi Furin-like cysteine rich region family protein 0.0024 0.0032 0.0086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0109 0.3968
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0064 0.011 0.011
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0035 0.0053 0.0075
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Brugia malayi hypothetical protein 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Brugia malayi hypothetical protein 0.0021 0.0025 0.0069
Loa Loa (eye worm) glutamate receptor 2 0.0015 0.0013 0.0036
Echinococcus granulosus protein Wnt 2 0.0009 0.0001 0.0001
Brugia malayi Metabotropic glutamate receptor precursor. 0.0033 0.0048 0.0132
Trypanosoma cruzi FHA domain containing protein, putative 0.0023 0.003 0.1084
Schistosoma mansoni lamin 0.0027 0.0038 0.0054
Plasmodium falciparum DNA gyrase subunit B 0.0009 0.0001 0.0021
Schistosoma mansoni wnt related 0.0009 0.0001 0.0001
Brugia malayi G protein-coupled receptor F59B2.13 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Schistosoma mansoni amine GPCR 0.0021 0.0025 0.0036
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0021 0.0025 0.0036
Giardia lamblia Replication factor C, subunit 1 0.0023 0.003 0.0117
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0009 0.0045
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0225 0.2524
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0055
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0013 0.001 0.1078
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0035 0.0053 0.0145
Giardia lamblia Fructose-bisphosphate aldolase 0.0928 0.1832 1
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0053 0.0287
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0025 0.0036
Trypanosoma cruzi cysteine peptidase, putative 0.0009 0 0.0015
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.009 0.0164 0.2663
Echinococcus multilocularis receptor type guanylyl cyclase 0.0015 0.0013 0.0013
Brugia malayi putative neuropeptide receptor 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Schistosoma mansoni opsin-like receptor 0.0021 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0164 0.031 0.0841
Echinococcus multilocularis FTZ F1 alpha 0.0035 0.0053 0.0053
Brugia malayi Dopamine receptor protein 1 0.0021 0.0025 0.0069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.1832 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0035 0.0053 0.0145
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Mycobacterium ulcerans fatty-acid-CoA ligase 0.009 0.0164 0.1836
Trypanosoma cruzi trypanothione reductase, putative 0.0146 0.0274 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.0008 0 0.0004
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0013 0.001 0.0103
Schistosoma mansoni alpha-1 adrenergic receptor 0.0021 0.0025 0.0036
Loa Loa (eye worm) wnt-4 protein 0.0009 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Onchocerca volvulus 0.0031 0.0045 0.0107
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0035 0.0053 0.0075
Echinococcus granulosus Nuclear hormone receptor HR96 0.0017 0.0016 0.0023
Plasmodium vivax vivapain-3 0.0009 0 0.0007
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0054 0.0601
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0016 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0035 0.0053 0.0145
Loa Loa (eye worm) Smad1 0.0016 0.0016 0.0043
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0102 0.0144
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0036 0.0054 0.0612
Schistosoma mansoni hypothetical protein 0.0344 0.0669 0.0945
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Loa Loa (eye worm) hypothetical protein 0.1858 0.3682 1
Schistosoma mansoni wnt related 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0021 0.0025 0.0054
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0054 0.0147
Loa Loa (eye worm) hypothetical protein 0.005 0.0083 0.0225
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0025 0.0025
Onchocerca volvulus 0.0031 0.0045 0.0107
Echinococcus granulosus Niemann Pick C1 protein 0.0725 0.1428 0.2016
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0021 0.0025 0.0069
Loa Loa (eye worm) steroid hormone receptor 0.0035 0.0053 0.0145
Loa Loa (eye worm) hypothetical protein 0.0027 0.0037 0.01
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0023 0.003 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0417 0.2276
Echinococcus multilocularis GPCR, family 2 0.0016 0.0015 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0016 0.0016
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0021 0.0026 0.0069
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0009 0.0319
Echinococcus granulosus Tolloid protein 1 0.0021 0.0026 0.0036
Schistosoma mansoni coup transcription factor 0.0035 0.0053 0.0075
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Schistosoma mansoni nuclear receptor nhr-48 0.0017 0.0016 0.0023
Loa Loa (eye worm) patched family protein 0.0031 0.0045 0.0122
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0.0013 0.0036
Echinococcus granulosus tyrosine kinase 0.0015 0.0013 0.0019
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Leishmania major DNA polymerase eta, putative 0.0066 0.0114 0.4168
Echinococcus granulosus glutamate NMDA receptor subunit 0.0047 0.0077 0.0108
Echinococcus granulosus microtubule associated protein 2 0.3564 0.7081 1
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0016 0.003
Brugia malayi hypothetical protein 0.0042 0.0066 0.018
Echinococcus granulosus poly (ADP ribose) polymerase 0.0014 0.0012 0.0017
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0105 0.0193 0.0193
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0025 0.0089
Brugia malayi hypothetical protein 0.0021 0.0025 0.0069
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0038 0.0103
Echinococcus multilocularis lamin dm0 0.0027 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0069
Schistosoma mansoni glutamate receptor NMDA 0.0029 0.0042 0.006
Echinococcus multilocularis tankyrase 0.0097 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0069
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0021 0.0025 0.0069
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0054 0.0601
Brugia malayi nuclear receptor RXR 0.0017 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0145
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0113 0.1261
Leishmania major hypothetical protein, conserved 0.0013 0.001 0.0373
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0013 0.0009 0.0092
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0092 0.0249
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0016 0.0022
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0025 0.0132
Brugia malayi Nuclear hormone receptor E75 0.0017 0.0016 0.0044
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0315 0.0611 1
Echinococcus granulosus dna polymerase eta 0.0093 0.017 0.024
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0035 0.0053 0.0053
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0315 0.0611 0.166
Schistosoma mansoni biogenic amine receptor 0.0021 0.0025 0.0036
Echinococcus granulosus 7tm_1 domain containing protein 0.0021 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0053 0.0144
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0013 0.0009 0.0337
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0036 0.0054 0.1979
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0064 0.2323
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0012 0.0008 0.0275
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0021 0.0025 0.0025
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0016 0.0268
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0053 0.0089 0.0126
Schistosoma mansoni lipoxygenase 0.0185 0.0352 0.0498
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0051 0.0084 0.3072
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0013 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Brugia malayi Cathepsin L-like precursor 0.0017 0.0016 0.0044
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0038 0.0103
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.1832 1
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0109 0.3968
Echinococcus granulosus poly ADP ribose polymerase 1 0.0105 0.0193 0.0273
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0081 0.0114
Plasmodium falciparum DNA topoisomerase 2 0.0027 0.0038 0.0615
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.0113 0.1271
Echinococcus multilocularis survival motor neuron protein 1 0.0711 0.14 0.14
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0016 0.0023
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0025 0.0895
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Echinococcus granulosus nuclear receptor nhr 48 0.0017 0.0016 0.0023
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.001 0.0014
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0021 0.0026 0.0069
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0013 0.001 0.0115
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0054 0.0612
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0315 0.0611 0.0863
Onchocerca volvulus 0.0031 0.0045 0.0107
Brugia malayi Pax transcription activation domain interacting protein 0.0023 0.003 0.0081
Loa Loa (eye worm) hypothetical protein 0.009 0.0164 0.0444
Schistosoma mansoni glutamate synthase 0.0013 0.001 0.0014
Onchocerca volvulus DNA topoisomerase 2 homolog 0.002 0.0023 0.0047
Onchocerca volvulus 0.0042 0.0066 0.0165
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0109 0.3968
Loa Loa (eye worm) TOPoisomerase family member 0.0027 0.0038 0.0102
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0066 0.0066
Brugia malayi Pre-SET motif family protein 0.0416 0.0812 0.2205
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.003 0.1084
Trypanosoma brucei DNA damage repair protein, putative 0.0013 0.0008 0.0306
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Trichomonas vaginalis replication factor C large subunit, putative 0.0023 0.003 0.016
Onchocerca volvulus 0.0036 0.0055 0.0136
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0021 0.0025 0.0069
Echinococcus multilocularis protein Wnt 1 0.0009 0.0001 0.0001
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0021 0.0025 0.0069
Schistosoma mansoni neuropeptide receptor 0.0021 0.0025 0.0036
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.037 0.0721 0.8131
Echinococcus multilocularis lamin 0.0027 0.0038 0.0038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0054 0.0612
Schistosoma mansoni chromosome transmission fidelity factor 0.0023 0.003 0.0042
Onchocerca volvulus 0.006 0.0102 0.0263
Brugia malayi RE15519p 0.0021 0.0025 0.0069
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0014 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0097 0.0263
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0013 0.0009 0.0092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Brugia malayi AKH receptor 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0145
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Onchocerca volvulus 0.0021 0.0025 0.0054
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0054
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0025 0.0025
Treponema pallidum NADH oxidase 0.0051 0.0084 0.0226
Brugia malayi ecdysone receptor 0.0017 0.0016 0.0044
Brugia malayi Tachykinin-like peptides receptor 99D 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Brugia malayi CHE-14 protein 0.0218 0.0417 0.1133
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0036 0.0054 0.0612
Brugia malayi hypothetical protein 0.0229 0.0439 0.1193
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0013 0.001 0.0167
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0013 0.0009 0.0337
Schistosoma mansoni tyrosine kinase 0.0015 0.0013 0.0019
Mycobacterium tuberculosis Probable dehydrogenase 0.0333 0.0647 0.7296
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0027 0.0038 0.0038
Echinococcus granulosus cytochrome P450 2K1 0.0013 0.0009 0.0013
Schistosoma mansoni microtubule-associated protein tau 0.3564 0.7081 1
Echinococcus granulosus orexin receptor type 2 0.0021 0.0025 0.0036
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0121 0.0225 0.2534
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0025 0.0025
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0013 0.001 0.0028
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Loa Loa (eye worm) fibroinase 0.0017 0.0016 0.0044
Echinococcus granulosus atrial natriuretic peptide receptor 0.0014 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.0028
Schistosoma mansoni glutamate receptor AMPA 0.0015 0.0013 0.0019
Schistosoma mansoni sodium-dependent amino acid transporter 0.0315 0.0611 0.0863
Schistosoma mansoni myosin xvIII 0.0021 0.0025 0.0036
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0014 0.0012 0.0033
Brugia malayi Probable DNA topoisomerase II 0.0027 0.0038 0.0102
Brugia malayi hypothetical protein 0.0042 0.0066 0.018
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0013 0.001 0.001
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0016 0.0022
Echinococcus granulosus neuropeptide receptor 0.0021 0.0025 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0109 0.3968
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0011 0.0005 0.0168
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Loa Loa (eye worm) TK/EGFR protein kinase 0.0024 0.0032 0.0086
Loa Loa (eye worm) programmed cell death 8 0.0013 0.001 0.0028
Schistosoma mansoni sodium/chloride dependent transporter 0.1858 0.3682 0.5201
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0225 0.061
Brugia malayi hypothetical protein 0.0023 0.003 0.0081
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1858 0.3682 0.5201
Brugia malayi MH1 domain containing protein 0.0009 0.0001 0.0004
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Brugia malayi Cathepsin L-like precursor 0.0011 0.0005 0.0015
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0082 0.299
Echinococcus granulosus glutamate receptor 2 0.0022 0.0027 0.0038
Echinococcus granulosus G protein coupled receptor 139 0.0021 0.0025 0.0036
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.001 0.0167
Echinococcus granulosus metabotropic glutamate receptor 2 0.0014 0.0012 0.0017
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0025 0.0036
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0083 0.1353
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0019 0.002 0.0029
Echinococcus granulosus lamin dm0 0.0027 0.0038 0.0054
Toxoplasma gondii thioredoxin reductase 0.0146 0.0274 0.4485
Loa Loa (eye worm) TK/INSR protein kinase 0.0053 0.0089 0.0242
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0315 0.0611 0.166
Treponema pallidum sodium- and chloride- dependent transporter 0.1858 0.3682 1
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0008 0.0306
Leishmania major hypothetical protein, conserved 0.0013 0.001 0.0373
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0013 0.0009 0.0104
Schistosoma mansoni amine GPCR 0.0021 0.0025 0.0036
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0054 0.009 0.0128
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0025 0.2806
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0016 0.0597
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0036
Echinococcus granulosus survival motor neuron protein 1 0.0711 0.14 0.1976
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0051 0.0084 0.0119
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0025 0.0025
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0025 0.0025
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0066 0.1084
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0013 0.0009 0.0092
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0016 0.0087
Loa Loa (eye worm) hypothetical protein 0.1858 0.3682 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0013 0.0034
Plasmodium vivax thioredoxin reductase, putative 0.0146 0.0274 0.4485
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0021 0.0026 0.0069
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.001 0.0053
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0016 0.0044
Plasmodium vivax DNA repair protein REV1, putative 0.0013 0.0008 0.0137
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0315 0.0611 0.166
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0054 0.009 0.3297
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0025 0.0036
Entamoeba histolytica thioredoxin reductase, putative 0.0013 0.001 0.0053
Brugia malayi Serotonin receptor 0.0021 0.0025 0.0069
Echinococcus multilocularis G-protein coupled receptor, putative 0.0021 0.0025 0.0025
Onchocerca volvulus 0.0013 0.001 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0109 0.3968
Echinococcus multilocularis gamma secretase subunit aph 1 0.0095 0.0173 0.0173
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0013 0.0009 0.0104
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.009 0.0491
Echinococcus multilocularis thyroid hormone receptor alpha 0.0035 0.0053 0.0053
Chlamydia trachomatis DNA gyrase subunit B 0.0015 0.0013 0.0193
Echinococcus multilocularis glutamate receptor 2 0.0015 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0122
Brugia malayi polk-prov protein 0.0013 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0069
Schistosoma mansoni tyrosine kinase 0.0053 0.0089 0.0126
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0013 0.001 0.0373
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Echinococcus granulosus neuropeptide FF receptor 2 0.0021 0.0025 0.0036
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0009 0 0.0001
Brugia malayi conserved hypotetical protein 0.0017 0.0016 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0084 0.3072
Schistosoma mansoni egf-like domain protein 0.0021 0.0026 0.0036
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0027 0.0038 0.0053
Brugia malayi Cathepsin L-like precursor 0.0017 0.0016 0.0044
Trichomonas vaginalis DNA topoisomerase II, putative 0.0027 0.0038 0.0203
Echinococcus multilocularis replication factor c subunit 1 0.0023 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0009 0.0045
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0036 0.0054 0.0294
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0035 0.0053 0.0145
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0064 0.0346
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0021 0.0025 0.0036
Brugia malayi Glutamate receptor 1 precursor 0.0015 0.0013 0.0036
Echinococcus multilocularis expressed protein 0.0035 0.0053 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0025 0.0025
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0066 0.0066
Trypanosoma brucei chrX additional, unordered contigs 0.0013 0.0008 0.0306
Echinococcus granulosus epidermal growth factor receptor 0.0024 0.0032 0.0045
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.001 0.0373
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0025 0.0036
Mycobacterium ulcerans ferredoxin reductase 0.0013 0.001 0.0103
Plasmodium falciparum glutathione reductase 0.0051 0.0084 0.1377
Brugia malayi follicle stimulating hormone receptor 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0033
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0066 0.0066
Onchocerca volvulus 0.0021 0.0025 0.0054
Onchocerca volvulus 0.0017 0.0016 0.003
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0025 0.0025
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0025 0.0036
Brugia malayi Cathepsin L-like precursor 0.0017 0.0016 0.0044
Echinococcus multilocularis nmda type glutamate receptor 0.0017 0.0016 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0035 0.0053 0.0145
Echinococcus granulosus FTZ F1 alpha 0.0035 0.0053 0.0075
Trypanosoma brucei trypanothione reductase 0.0146 0.0274 1
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0315 0.0611 0.0611
Trichomonas vaginalis glutamate synthase, putative 0.0013 0.001 0.0053
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0013 0.001 0.0053
Loa Loa (eye worm) hypothetical protein 0.0267 0.0515 0.1398
Echinococcus multilocularis wnt family member wnt11 2 0.0009 0.0001 0.0001
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0036 0.0054 0.0887
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0013 0.0009 0.0104
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0013 0.001 0.0115
Schistosoma mansoni histamine h1 receptor 0.0021 0.0025 0.0036
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0009 0.0009
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0025 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0013 0.0009 0.0104
Schistosoma mansoni lipoxygenase 0.011 0.0203 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0122
Echinococcus granulosus poly adp ribose polymerase 2 0.0064 0.011 0.0156
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0025 0.0036
Onchocerca volvulus Serine\/threonine kinase homolog 0.0054 0.009 0.0231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0109 0.3968
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0021 0.0026 0.0949
Trypanosoma brucei DNA polymerase eta, putative 0.0093 0.017 0.6186
Schistosoma mansoni glutamate receptor kainate 0.0015 0.0013 0.0019
Onchocerca volvulus 0.0017 0.0016 0.003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Brugia malayi Patched family protein 0.0031 0.0045 0.0122
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0051 0.0084 0.0084
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0315 0.0611 0.0863
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Leishmania major hypothetical protein, conserved 0.0012 0.0008 0.0275
Brugia malayi intermediate filament protein 0.0027 0.0038 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.003 0.016
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0028 0.0028
Onchocerca volvulus 0.0021 0.0025 0.0054
Brugia malayi Cathepsin L-like precursor 0.0011 0.0005 0.0015
Echinococcus granulosus neuropeptide receptor 0.0021 0.0025 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0025 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0064 0.2323
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0225 0.819
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0025 0.0036
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0051 0.0084 0.3072
Leishmania major pantothenate kinase subunit, putative 0.0009 0.0002 0.0059
Brugia malayi hypothetical protein 0.0032 0.0048 0.0129
Schistosoma mansoni topbp1 0.0023 0.003 0.0042
Onchocerca volvulus DNA topoisomerase 2 homolog 0.002 0.0023 0.0047
Echinococcus granulosus somatostatin receptor 0.0021 0.0025 0.0036
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0054 0.0147
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0008 0.0306
Loa Loa (eye worm) hypothetical protein 0.0042 0.0066 0.018
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.03
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.009 0.0164 0.1846
Onchocerca volvulus 0.0017 0.0016 0.003
Echinococcus granulosus GPCR family 2 0.0016 0.0015 0.0022
Schistosoma mansoni glutamate receptor kainate 0.0015 0.0013 0.0019
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0025 0.0265
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.001 0.0053
Mycobacterium ulcerans hypothetical protein 0.0013 0.0008 0.0082
Schistosoma mansoni retinoic acid receptor RXR 0.0035 0.0053 0.0075
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0013 0.001 0.0053
Loa Loa (eye worm) hypothetical protein 0.0068 0.0119 0.0324
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0025 0.0036
Leishmania major cathepsin L-like protease 0.0017 0.0016 0.0597
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0064 0.0112 0.0303
Echinococcus multilocularis dro:myosuppressin receptor 0.0021 0.0025 0.0025
Echinococcus multilocularis nuclear receptor nhr 48 0.0017 0.0016 0.0016
Schistosoma mansoni DNA ligase IV 0.0023 0.003 0.0042
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0013 0.001 0.0373
Echinococcus granulosus expressed protein 0.0035 0.0053 0.0075
Echinococcus granulosus Niemann Pick C1 protein 0.0508 0.0994 0.1404
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0013 0.001 0.0014
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0009 0.0045
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.003 0.016
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0064 0.009
Echinococcus granulosus dro:myosuppressin receptor 0.0021 0.0025 0.0036
Entamoeba histolytica hypothetical protein 0.0072 0.0126 0.0686
Leishmania major cathepsin L-like protease 0.0063 0.0109 0.3968
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0081
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0054 0.0601
Mycobacterium ulcerans monoxygenase 0.0013 0.001 0.0103
Onchocerca volvulus 0.0031 0.0045 0.0107
Brugia malayi hypothetical protein 0.0315 0.0611 0.166
Plasmodium falciparum protein kinase, putative 0.0008 0 0.0004
Mycobacterium ulcerans acetyl-CoA synthetase 0.0036 0.0054 0.0601
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.009 0.0491
Loa Loa (eye worm) hypoxia-induced factor 1 0.0151 0.0284 0.0772
Schistosoma mansoni hypothetical protein 0.0042 0.0066 0.0094
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0333 0.0647 0.7296
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0025 0.0025
Mycobacterium leprae putative cytochrome p450 0.0013 0.0009 0.0006
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0051 0.0084 0.095
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0315 0.0611 0.0611
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0013 0.0009 0.0104
Echinococcus granulosus sodium and chloride dependent glycine 0.0315 0.0611 0.0863
Schistosoma mansoni DNA polymerase IV / kappa 0.0013 0.0008 0.0012
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0013 0.001 0.0103
Loa Loa (eye worm) DR-78 0.0017 0.0016 0.0044
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0051 0.0084 0.0939
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0083 0.3017
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0084 0.0229
Echinococcus granulosus poly (ADP ribose) polymerase 0.0029 0.0041 0.0058
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0025 0.0069
Echinococcus multilocularis tyrosine kinase 0.0015 0.0013 0.0013
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.017 0.017
Onchocerca volvulus 0.0044 0.007 0.0176
Brugia malayi hypothetical protein 0.0019 0.002 0.0055
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0013 0.001 0.0373
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0015 0.0042
Brugia malayi orphan nuclear receptor NR2E1 0.0017 0.0016 0.0044
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0109 0.3968
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0025 0.0025
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0051 0.0084 0.3072
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0009 0.0045
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0084 0.3072
Schistosoma mansoni hypothetical protein 0.0016 0.0015 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.009 0.0491
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0051 0.0084 0.1377
Brugia malayi nuclear hormone receptor family member odr-7 0.0017 0.0016 0.0044
Echinococcus granulosus peptide allatostatin:somatostatin 0.0021 0.0025 0.0036
Brugia malayi MH1 domain containing protein 0.0016 0.0016 0.0043
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0185 0.0352 0.0498
Schistosoma mansoni thyroid hormone receptor 0.0035 0.0053 0.0075
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0025 0.0067
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0051 0.0084 0.3072
Echinococcus multilocularis somatostatin receptor 0.0021 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0016 0.0087
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0019 0.002 0.0055
Onchocerca volvulus 0.0021 0.0025 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0147
Echinococcus multilocularis sodium and chloride dependent glycine 0.0315 0.0611 0.0611
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0015 0.0015
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0013 0.001 0.0167
Echinococcus multilocularis G protein coupled receptor 139 0.0021 0.0025 0.0025
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0013 0.001 0.0103
Leishmania major acetyl-CoA synthetase, putative 0.0036 0.0054 0.1979
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0025 0.0036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0016 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.009 0.0491
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0015 0.0015
Trypanosoma cruzi cysteine proteinase, putative 0.0009 0 0.0015
Brugia malayi wnt family protein 0.0009 0.0001 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.1832 1
Leishmania major extracellular receptor, putative 0.0014 0.0012 0.0449
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0083 0.3017
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0023 0.003 0.0081
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0086 0.0154 0.1735
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0017 0.0016 0.003
Onchocerca volvulus 0.0315 0.0611 0.1648
Schistosoma mansoni survival motor neuron protein 0.0145 0.0272 0.0385
Entamoeba histolytica disulphide oxidoreductase, putative 0.0013 0.001 0.0053
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0051 0.0084 1
Onchocerca volvulus 0.0036 0.0054 0.0133
Trypanosoma brucei Aph-1 protein, putative 0.0037 0.0057 0.2087
Schistosoma mansoni hypothetical protein 0.021 0.0402 0.0567
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0036 0.0054 0.0054
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0013 0.0009 0.0104
Mycobacterium tuberculosis Probable reductase 0.0333 0.0647 0.7296
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.001 0.0373
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0084 0.3072
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0103
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0013 0.001 0.0014
Brugia malayi Protein kinase domain containing protein 0.0029 0.0042 0.0114
Schistosoma mansoni glutamate receptor AMPA 0.0015 0.0013 0.0019
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0013 0.001 0.0053
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0016 0.0016
Brugia malayi Cytochrome P450 family protein 0.0054 0.0092 0.0249
Schistosoma mansoni sulfide quinone reductase 0.0013 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0042 0.0066 0.018
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Plasmodium falciparum transporter, putative 0.0315 0.0611 1
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0013 0.0009 0.0337
Brugia malayi Patched related family protein 4 0.0031 0.0045 0.0122
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Echinococcus multilocularis serotonin transporter 0.1858 0.3682 0.3682
Schistosoma mansoni biogenic amine receptor 0.0021 0.0025 0.0036
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0225 0.061
Brugia malayi sulfakinin receptor protein 0.0021 0.0025 0.0069
Echinococcus multilocularis cysteine protease 0.0017 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Plasmodium vivax DNA topoisomerase II, putative 0.0027 0.0038 0.0615
Brugia malayi ecdysteroid receptor 0.0035 0.0053 0.0145
Trypanosoma cruzi DNA polymerase eta, putative 0.0066 0.0114 0.4168
Echinococcus granulosus protein Wnt 1 0.0009 0.0001 0.0001
Brugia malayi Cathepsin L-like precursor 0.0017 0.0016 0.0044
Brugia malayi hypothetical protein 0.0031 0.0045 0.0122
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0024 0.0032 0.1172
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0084 0.3072
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.001 0.0167
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0023 0.003 0.0323
Echinococcus granulosus single minded 2 0.0036 0.0055 0.0078
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0416 0.0812 0.2205
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0014 0.0012 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0039 0.1415
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0016 0.0596
Mycobacterium leprae Conserved hypothetical protein 0.0013 0.0009 0.0006
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0035 0.0053 0.0075
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0025 0.0036
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0064 0.011 0.0156
Onchocerca volvulus 0.0021 0.0025 0.0054
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0013 0.001 0.0053
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0051 0.1873
Leishmania major DNA polymerase kappa, putative 0.004 0.0064 0.2323
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0021
Loa Loa (eye worm) hypothetical protein 0.0315 0.0611 0.166
Brugia malayi tailless protein 0.0017 0.0016 0.0044
Echinococcus granulosus g protein coupled receptor 0.0021 0.0025 0.0036
Trypanosoma brucei DNA topoisomerase ii 0.0021 0.0026 0.0949
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0017 0.0016 0.0016
Echinococcus granulosus sex peptide receptor 0.0021 0.0025 0.0036
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0025 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0035 0.0053 0.0145
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0023 0.003 0.1084
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0025 0.0036
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0315 0.0611 0.0863
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0025 0.0036
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0928 0.1832 1
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0036 0.0054 0.0601
Trichomonas vaginalis antibiotic synthetase, putative 0.0036 0.0054 0.0294
Echinococcus granulosus insulin receptor 0.0053 0.0089 0.0126
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.001 0.0373
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0013 0.001 0.0115
Trichomonas vaginalis rotamase, putative 0.0035 0.0053 0.0287
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.017 0.024
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0005 0.0028
Leishmania major hypothetical protein, conserved 0.0013 0.001 0.0373
Brugia malayi hypothetical protein 0.0031 0.0045 0.0122
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0025 0.0895
Brugia malayi gamma-secretase subunit aph-1 0.0095 0.0173 0.0469
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0021 0.0026 0.0949
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0039 0.1415
Echinococcus multilocularis 0.0013 0.0009 0.0009
Echinococcus granulosus intermediate filament protein 0.0027 0.0038 0.0054
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0044 0.0071 0.01
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0102 0.0102
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0013 0.0008 0.0137
Echinococcus multilocularis sex peptide receptor 0.0021 0.0025 0.0025
Echinococcus multilocularis dna polymerase kappa 0.004 0.0064 0.0064
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0013 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0121 0.0225 0.061
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Schistosoma mansoni nuclear hormone receptor 0.0035 0.0053 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0109 0.3968
Echinococcus multilocularis dna polymerase eta 0.0093 0.017 0.017
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0009 0.0319
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Brugia malayi Calcium binding EGF domain containing protein 0.0021 0.0026 0.0069
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0017 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0101 0.0184 0.0499
Echinococcus multilocularis epidermal growth factor receptor 0.0024 0.0032 0.0032
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0025 0.0277
Onchocerca volvulus 0.0013 0.0009 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0016 0.0597
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.002 0.0029
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0025 0.0025
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0121 0.0225 0.2524
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0053 0.0053
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0023 0.003 0.016
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0064 0.2323
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0013 0.0009 0.0104
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0066 0.1084
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0013 0.001 0.001
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1858 0.3682 1
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0064 0.011 0.4027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0025 0.0036
Toxoplasma gondii hypothetical protein 0.0315 0.0611 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0725 0.1428 0.1428
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0016 0.003
Brugia malayi Serotonin receptor 0.0021 0.0025 0.0069
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0013 0.0009 0.0104
Loa Loa (eye worm) hypothetical protein 0.0711 0.14 0.38
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Brugia malayi Fibulin-1 precursor 0.0021 0.0026 0.0069
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0069
Echinococcus granulosus cathepsin l1 0.0017 0.0016 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0023 0.0122
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0009 0 0.0015
Loa Loa (eye worm) norepinephrine transporter 0.1858 0.3682 1
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0051 0.084
Leishmania major DNA damage repair protein, putative 0.0013 0.0008 0.0306
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0021 0.0025 0.0036
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0051 0.0084 0.1377
Schistosoma mansoni zinc finger protein 0.0017 0.0016 0.0023
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0054 0.009 0.009
Brugia malayi wnt family protein 0.0009 0.0001 0.0002
Echinococcus granulosus g-protein coupled receptor 0.0021 0.0025 0.0036
Onchocerca volvulus Arrow homolog 0.0021 0.0026 0.0055
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0013 0.0009 0.0092
Onchocerca volvulus Protein patched homolog 0.0031 0.0045 0.0107
Echinococcus multilocularis ecdysone induced protein 78C 0.0035 0.0053 0.0053
Onchocerca volvulus Nischarin homolog 0.0229 0.0439 0.118
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0009 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0016 0.0087
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0021 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0315 0.0611 0.0863
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0105 0.0193 0.0273
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0029 0.0042 0.006
Trypanosoma cruzi polo-like protein kinase, putative 0.0054 0.009 0.3297
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0122
Schistosoma mansoni DNA polymerase eta 0.0093 0.017 0.024
Loa Loa (eye worm) nuclear factor I 0.0009 0.0001 0.0004
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0453 0.0886 1
Brugia malayi hypothetical protein 0.0072 0.0126 0.0342
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0025 0.0895
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0036 0.0054 0.1979
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0005 0.0168
Brugia malayi hypothetical protein 0.0014 0.0012 0.0033
Echinococcus multilocularis thioredoxin glutathione reductase 0.0146 0.0274 0.0274
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0035 0.0053 0.0145

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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