Detailed information for compound 1063110

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 561.715 | Formula: C32H43N5O4
  • H donors: 4 H acceptors: 4 LogP: 3.81 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC[C@H]([C@H](C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)NCc1ccc(cc1)C(=N)N)NC(=O)[C@@H](Cc1ccccc1)O)C
  • InChi: 1S/C32H43N5O4/c1-3-20(2)28(36-31(40)27(38)17-21-9-5-4-6-10-21)32(41)37-25-12-8-7-11-24(25)18-26(37)30(39)35-19-22-13-15-23(16-14-22)29(33)34/h4-6,9-10,13-16,20,24-28,38H,3,7-8,11-12,17-19H2,1-2H3,(H3,33,34)(H,35,39)(H,36,40)/t20-,24+,25+,26+,27-,28-/m1/s1
  • InChiKey: ZHTYBHJRYWPRIG-DFRFQQMASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor II (thrombin) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0035 0.0044 0.0122
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0066 0.0828
Schistosoma mansoni ap endonuclease 0.0059 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0054 0.0095 0.0523
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0345 0.4378
Echinococcus granulosus heat shock protein 67b2 0.0031 0.0032 0.0031
Schistosoma mansoni growth hormone secretagogue receptor 0.0051 0.0087 0.0087
Toxoplasma gondii succinate dehydrogenase [ubiquinone] iron-sulfur protein 0.0051 0.0087 0.1815
Schistosoma mansoni microtubule-associated protein tau 0.3681 1 1
Chlamydia trachomatis succinate dehydrogenase flavoprotein subunit 0.0022 0.0007 0.0061
Schistosoma mansoni phosphatidylserine receptor 0.0054 0.0096 0.0096
Brugia malayi putative neuropeptide receptor 0.0051 0.0087 0.0473
Plasmodium vivax flavoprotein subunit of succinate dehydrogenase, putative 0.0022 0.0007 0.0238
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0641 0.2562
Treponema pallidum fructose-bisphosphate aldolase 0.0931 0.2489 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0054 0.0095 0.0519
Echinococcus multilocularis muscleblind protein 0.0604 0.1598 0.1597
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0087 0.0087
Brugia malayi cathepsin L-like precursor 0.0024 0.0014 0.0074
Mycobacterium ulcerans esterase/lipase LipP 0.0076 0.0156 0.0408
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0018 0.0092
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0095 0.0095
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0036 0.0047 0.1839
Echinococcus granulosus neuropeptide receptor 0.0051 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0096
Mycobacterium ulcerans thioesterase TesA 0.0064 0.0123 0.0323
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0076 0.0156 0.0155
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0111 0.0251 0.3181
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0152 0.0363 0.1444
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0077 0.0158 0.0415
Onchocerca volvulus Protein ultraspiracle homolog 0.0054 0.0095 0.0438
Loa Loa (eye worm) hypothetical protein 0.0063 0.0119 0.0652
Toxoplasma gondii cathepsin CPL 0.0036 0.0047 0.0973
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0048 0.0605
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0217 0.0217
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0193 0.0475 0.0474
Toxoplasma gondii rhodanese family domain-containing protein 0.0031 0.0032 0.066
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0604 0.1598 0.8746
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0051 0.0087 0.0086
Toxoplasma gondii thioredoxin reductase 0.0047 0.0077 0.1608
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0476
Brugia malayi Cathepsin L-like precursor 0.0036 0.0047 0.0253
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0059 0.0109 0.0599
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0486 0.1275 0.1404
Brugia malayi G protein-coupled receptor 0.0051 0.0087 0.0473
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0054 0.0095 0.0519
Schistosoma mansoni DNA helicase recq5 0.0062 0.0118 0.0118
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0048 0.0176
Entamoeba histolytica recQ family helicase, putative 0.0068 0.0133 0.048
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0096
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0051 0.0087 0.0227
Trypanosoma cruzi DNA repair protein, putative 0.0033 0.0037 0.0462
Echinococcus granulosus protein quaking 0.0028 0.0023 0.0023
Brugia malayi glutathione reductase 0.0047 0.0077 0.0418
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0066 0.0828
Mycobacterium ulcerans DNA polymerase IV 0.0108 0.0243 0.0637
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.01 0.0222 0.4666
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.04 0.04
Mycobacterium tuberculosis Conserved hypothetical protein 0.0031 0.0032 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0054 0.0095 0.0519
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0152 0.0363 0.1444
Loa Loa (eye worm) hypothetical protein 0.0076 0.0156 0.0852
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0019 0.073
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0104 0.0232 0.1268
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0076 0.0156 0.0165
Brugia malayi hypothetical protein 0.0051 0.0087 0.0473
Entamoeba histolytica hypothetical protein 0.0031 0.0032 0.0072
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.008 0.008
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0033 0.0037 0.0462
Echinococcus granulosus RUN 0.0111 0.0252 0.0251
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0111 0.0251 0.3181
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0054 0.0096 0.2007
Brugia malayi nuclear receptor RXR 0.0025 0.0018 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.021 0.0826
Wolbachia endosymbiont of Brugia malayi succinate dehydrogenase flavoprotein subunit 0.0022 0.0007 0.0061
Brugia malayi beta-lactamase family protein 0.0076 0.0156 0.0848
Giardia lamblia Sgs1 DNA helicase, putative 0.0062 0.0118 0.044
Trypanosoma cruzi DNA polymerase kappa, putative 0.0108 0.0243 0.3079
Brugia malayi Dopamine receptor 0.0051 0.0087 0.0473
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0053 0.0195
Onchocerca volvulus 0.0024 0.0014 0.0048
Loa Loa (eye worm) hypothetical protein 0.0054 0.0095 0.0523
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0152 0.0363 0.1444
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0078
Loa Loa (eye worm) hypothetical protein 0.0104 0.0232 0.1268
Brugia malayi MH2 domain containing protein 0.0125 0.0288 0.1573
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0641 0.2562
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0253 0.064 0.0639
Entamoeba histolytica rodhanase-like domain containing protein 0.0152 0.0363 0.141
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0076 0.0156 0.0572
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0087 0.0477
Trypanosoma cruzi NADH dehydrogenase, putative 0.0033 0.0039 0.0482
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0022 0.0008 0.0078
Echinococcus multilocularis cathepsin L cysteine protease 0.0036 0.0047 0.0046
Echinococcus multilocularis microtubule associated protein 2 0.3681 1 1
Trichomonas vaginalis rotamase, putative 0.0039 0.0053 0.0195
Schistosoma mansoni hypothetical protein 0.1302 0.3504 0.3504
Loa Loa (eye worm) hypothetical protein 0.0049 0.008 0.044
Loa Loa (eye worm) histone methyltransferase 0.0032 0.0035 0.0192
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0087 0.0087
Echinococcus multilocularis L aminoadipate semialdehyde 0.0177 0.0432 0.0432
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0032 0.0399
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0051 0.0087 0.0087
Trichomonas vaginalis DNA helicase recq, putative 0.0089 0.0192 0.0754
Echinococcus granulosus cathepsin l cysteine peptidase 0.0036 0.0047 0.0046
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0035 0.0044 0.0546
Echinococcus granulosus G protein coupled receptor 139 0.0051 0.0087 0.0086
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0035 0.0044 0.0119
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0325 0.4127
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.0787 1
Loa Loa (eye worm) beta-lactamase 0.0076 0.0156 0.0852
Trichomonas vaginalis cdc25c, putative 0.0031 0.0032 0.0111
Trypanosoma brucei DNA polymerase IV, putative 0.0108 0.0243 0.3079
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0038 0.0051 0.0634
Leishmania major hypothetical protein, unknown function 0.0031 0.0032 0.0399
Giardia lamblia DINP protein human, muc B family 0.0065 0.0124 0.0468
Brugia malayi Serotonin receptor 0.0051 0.0087 0.0473
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0076 0.0156 0.0848
Schistosoma mansoni protein phosphatase 2C 0.0054 0.0096 0.0096
Mycobacterium tuberculosis Conserved hypothetical protein 0.005 0.0085 0.0087
Onchocerca volvulus 0.0029 0.0028 0.0112
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0193 0.0475 0.0518
Schistosoma mansoni lamin 0.0029 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0076 0.0156 0.0852
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0005 0.00000000028147
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.038 0.0985 0.2579
Schistosoma mansoni hypothetical protein 0.0031 0.0032 0.0032
Entamoeba histolytica hypothetical protein 0.005 0.0084 0.0283
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0931 0.2489 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0047 0.0132
Schistosoma mansoni myosin xvIII 0.0051 0.0087 0.0087
Echinococcus multilocularis zinc finger protein 0.0035 0.0042 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.021 0.0826
Trichomonas vaginalis glutathione reductase, putative 0.0022 0.0008 0.0016
Echinococcus multilocularis lamin dm0 0.0029 0.0028 0.0027
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0022 0.0008 0.0097
Echinococcus granulosus 7tm_1 domain containing protein 0.0051 0.0087 0.0086
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Brugia malayi G protein-coupled receptor F59B2.13 0.0051 0.0087 0.0473
Echinococcus multilocularis caspase 0.0253 0.064 0.0639
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0325 0.4127
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0325 0.4127
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0018 0.0096
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Echinococcus granulosus apoptotic protease activating factor 1 0.0089 0.0192 0.0191
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0054 0.0095 0.0523
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0076 0.0156 0.0408
Onchocerca volvulus 0.0152 0.0363 0.1725
Schistosoma mansoni caspase-7 (C14 family) 0.0185 0.0453 0.0453
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0066 0.0828
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0031 0.0032 0.0399
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0111 0.0251 0.5268
Brugia malayi jmjC domain containing protein 0.0054 0.0096 0.0521
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0048 0.0176
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.0243 0.3079
Echinococcus multilocularis protein patched 0.0043 0.0065 0.0064
Echinococcus granulosus g protein coupled receptor 0.0051 0.0087 0.0086
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0014 0.0014
Trypanosoma cruzi metacaspase, putative 0.0096 0.021 0.2659
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0047 0.0075 0.0945
Onchocerca volvulus Fatty acid synthase homolog 0.0139 0.0327 0.1552
Schistosoma mansoni hypothetical protein 0.0051 0.0087 0.0087
Schistosoma mansoni biogenic amine receptor 0.0051 0.0087 0.0087
Schistosoma mansoni hypothetical protein 0.0033 0.0038 0.0038
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0063 0.012 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Brugia malayi Calcitonin receptor-like protein seb-1 0.0104 0.0232 0.1264
Trichomonas vaginalis cdc25c, putative 0.0152 0.0363 0.1444
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0104 0.0232 0.1264
Echinococcus granulosus CREB binding protein 0.0074 0.0149 0.0148
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0087 0.0087
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0319 0.0818 0.0818
Onchocerca volvulus 0.0152 0.0363 0.1725
Leishmania major hypothetical protein, conserved 0.0054 0.0096 0.1212
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0047 0.0075 0.1566
Loa Loa (eye worm) hypothetical protein 0.0036 0.0047 0.0257
Mycobacterium ulcerans polyketide synthase Pks13 0.0115 0.0263 0.0689
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0325 0.4127
Echinococcus granulosus m phase inducer phosphatasecdc25 0.0152 0.0363 0.0362
Echinococcus multilocularis phd:f box containing protein 0.0054 0.0096 0.0095
Trypanosoma brucei unspecified product 0.0035 0.0043 0.0534
Trypanosoma cruzi metacaspase 5, putative 0.0096 0.021 0.2659
Echinococcus multilocularis lysine specific demethylase 5A 0.0203 0.0503 0.0502
Trypanosoma cruzi metacaspase, putative 0.0096 0.021 0.2659
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0226 0.0226
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0077 0.0158 0.0168
Echinococcus granulosus succinate dehydrogenase ubiquinone iron sulfur 0.0023 0.001 0.0009
Mycobacterium ulcerans lipase LipD 0.0076 0.0156 0.0408
Plasmodium falciparum JmjC domain-containing protein, putative 0.0054 0.0096 0.3793
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0022 0.0008 0.0078
Schistosoma mansoni biogenic amine receptor 0.0051 0.0087 0.0087
Schistosoma mansoni hypothetical protein 0.002 0.0004 0.0004
Brugia malayi ecdysone receptor 0.0025 0.0018 0.0092
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0064 0.0123 0.0307
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0062 0.0117 0.0307
Schistosoma mansoni neuropeptide receptor 0.0051 0.0087 0.0087
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0059 0.0109 0.1383
Leishmania major hypothetical protein, conserved 0.0076 0.0156 0.1972
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0018 0.069
Echinococcus granulosus phd:f box containing protein 0.0054 0.0096 0.0095
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0022 0.0008 0.0305
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0054 0.0095 0.0095
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0035 0.0044 0.0905
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0051 0.0087 0.0473
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0076 0.0156 0.1972
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0019 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0032 0.0399
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0018 0.0365
Schistosoma mansoni hypothetical protein 0.0031 0.0032 0.0032
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase SseA (rhodanese) (thiosulfate cyanide transsulfurase) (thiosulfate thiotransferase) 0.0031 0.0032 0.0028
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0096
Schistosoma mansoni inositol monophosphatase 0.0037 0.005 0.005
Brugia malayi follicle stimulating hormone receptor 0.0051 0.0087 0.0473
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.005 0.0084 0.3323
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0051 0.0087 0.0087
Brugia malayi jmjC domain containing protein 0.0333 0.0857 0.4685
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0117 0.0269 0.029
Brugia malayi acetyltransferase, GNAT family protein 0.0319 0.0818 0.4475
Echinococcus granulosus centrosomal protein of 41 kDa 0.0031 0.0032 0.0031
Echinococcus multilocularis G-protein coupled receptor, putative 0.0051 0.0087 0.0086
Trypanosoma brucei metacaspase MCA2 0.0096 0.021 0.2659
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0051 0.0087 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0082 0.1031
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0117 0.0269 0.069
Trichomonas vaginalis bromodomain-containing protein, putative 0.0097 0.0212 0.0835
Loa Loa (eye worm) CBP-B 0.0082 0.0171 0.0933
Toxoplasma gondii ABC1 family protein 0.0076 0.0156 0.3265
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0033 0.0039 0.151
Toxoplasma gondii type I fatty acid synthase, putative 0.0055 0.0098 0.2045
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0008 0.0097
Giardia lamblia Histone acetyltransferase GCN5 0.0085 0.0179 0.0689
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.0221 0.1207
Echinococcus multilocularis orexin receptor type 2 0.0051 0.0087 0.0086
Echinococcus granulosus FTZ F1 alpha 0.0054 0.0095 0.0095
Echinococcus granulosus dual specificity mitogen activated protein 0.0076 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0076 0.0156 0.0155
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0031 0.0032 0.0399
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0038 0.0051 0.0634
Trichomonas vaginalis Phage shock protein E precursor, putative 0.0031 0.0032 0.0111
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.005 0.063
Brugia malayi larval opioid receptor 0.0051 0.0087 0.0473
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.021 0.0826
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0044 0.0044
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0087 0.0087
Schistosoma mansoni nuclear receptor 0.0025 0.0018 0.0018
Entamoeba histolytica hypothetical protein, conserved 0.0031 0.0032 0.0072
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0031 0.0032 0.0399
Mycobacterium ulcerans replicative DNA helicase DnaB 0.038 0.0985 0.2591
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Schistosoma mansoni amine GPCR 0.0051 0.0087 0.0087
Wolbachia endosymbiont of Brugia malayi sulfurtransferase 0.0031 0.0032 0.0318
Mycobacterium ulcerans succinate dehydrogenase flavoprotein subunit 0.0022 0.0007 0.0016
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0075 0.0154 0.0153
Onchocerca volvulus 0.0177 0.0432 0.2056
Echinococcus granulosus histone acetyltransferase KAT2B 0.0306 0.0783 0.0782
Brugia malayi indoleamine 2,3-dioxygenase 0.0636 0.1686 0.9224
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0106 0.0238 0.0611
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.0026 0.0026
Brugia malayi tailless protein 0.0025 0.0018 0.0092
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0193 0.0475 0.6038
Trichomonas vaginalis rotamase, putative 0.0038 0.0051 0.0185
Brugia malayi nuclear receptor NHR-88 0.0025 0.0018 0.0092
Leishmania major hypothetical protein, conserved 0.0026 0.0018 0.022
Brugia malayi Muscleblind-like protein 0.0604 0.1598 0.8746
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.005 0.0146
Echinococcus granulosus cathepsin l1 0.0036 0.0047 0.0046
Mycobacterium ulcerans thioesterase 0.0064 0.0123 0.0323
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0251 0.0991
Leishmania major succinate dehydrogenase flavoprotein, putative 0.0022 0.0007 0.0076
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0198 0.0487 0.0487
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Leishmania major hypothetical protein, conserved 0.0031 0.0032 0.0399
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0022 0.0008 0.0097
Loa Loa (eye worm) hypothetical protein 0.0121 0.0279 0.1527
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0087 0.0087
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0217 0.0217
Echinococcus granulosus mitogen activated protein kinase 3 0.0111 0.0251 0.025
Brugia malayi Bromodomain containing protein 0.0075 0.0152 0.0826
Toxoplasma gondii flavoprotein subunit of succinate dehydrogenase 0.0022 0.0007 0.0126
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0077 0.0158 0.04
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0047 0.0075 0.0407
Schistosoma mansoni hypothetical protein 0.0051 0.0087 0.0087
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0087 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0403 0.1603
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0099 0.0098
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0222 0.0222
Echinococcus multilocularis dro:myosuppressin receptor 0.0051 0.0087 0.0086
Mycobacterium leprae Probable thiosulfate sulfurtransferase SseA (RHODANESE) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE) 0.0031 0.0032 0.0067
Entamoeba histolytica deoxycytidyl transferase, putative 0.005 0.0085 0.0288
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0111 0.0252 0.1378
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.005 0.0085 0.0085
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0048 0.008 0.0436
Trypanosoma brucei DNA polymerase eta, putative 0.005 0.0085 0.1077
Mycobacterium ulcerans succinate dehydrogenase flavoprotein subunit 0.0022 0.0007 0.0016
Trichomonas vaginalis esterase, putative 0.0076 0.0156 0.0609
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0251 0.3181
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0049 0.0082 0.0082
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0048 0.0176
Leishmania major hypothetical protein, conserved 0.0031 0.0032 0.0399
Brugia malayi Melatonin receptor type 1A 0.0051 0.0087 0.0473
Schistosoma mansoni neuropeptide receptor 0.0051 0.0087 0.0087
Echinococcus multilocularis heat shock protein 67b2 0.0031 0.0032 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0325 0.4127
Echinococcus multilocularis thyroid hormone receptor alpha 0.0327 0.084 0.0839
Echinococcus multilocularis jumonji domain containing protein 0.0087 0.0186 0.0185
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0345 0.4378
Loa Loa (eye worm) hypothetical protein 0.0152 0.0363 0.1988
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0047 0.0075 0.0945
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0054 0.0095 0.0095
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0068 0.0133 0.1681
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0325 0.4127
Brugia malayi CHE-14 protein 0.0043 0.0065 0.0353
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0022 0.0008 0.0002
Toxoplasma gondii hypothetical protein 0.005 0.0083 0.1737
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Onchocerca volvulus Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial homolog 0.0022 0.0007 0.0012
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.003 0.003 0.0608
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0156 0.1972
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.021 0.0826
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0087 0.0087
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0048 0.0176
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.0047 0.0075 0.018
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.0152 0.0363 0.0362
Echinococcus multilocularis somatostatin receptor 0.0051 0.0087 0.0086
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0065 0.0064
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0062 0.0117 0.0291
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0076 0.0156 0.1979
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.0787 1
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0636 0.1686 0.9225
Echinococcus granulosus bloom syndrome protein 0.0089 0.0192 0.0191
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0051 0.0087 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0032 0.0111
Trypanosoma brucei NADH dehydrogenase 0.0033 0.0039 0.0482
Echinococcus multilocularis neuropeptide FF receptor 2 0.0051 0.0087 0.0086
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0113 0.0256 0.0256
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0636 0.1686 0.1685
Schistosoma mansoni terminal deoxycytidyl transferase 0.005 0.0085 0.0085
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) iron sulfur 0.0033 0.0037 0.0036
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0087 0.0086
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0024 0.0014 0.0019
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0087 0.0086
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0325 0.4127
Plasmodium falciparum flavoprotein subunit of succinate dehydrogenase 0.0022 0.0007 0.0238
Onchocerca volvulus 0.0107 0.0241 0.1135
Brugia malayi hypothetical protein 0.0051 0.0087 0.0473
Echinococcus multilocularis G protein coupled receptor 139 0.0051 0.0087 0.0086
Leishmania major succinate dehydrogenase, putative 0.0033 0.0037 0.0461
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0082 0.0172 0.0182
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0325 0.4127
Echinococcus multilocularis expressed conserved protein 0.0094 0.0205 0.0204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0087 0.0087
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0047 0.0076 0.0076
Brugia malayi hypothetical protein 0.0051 0.0087 0.0473
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0106 0.0238 0.0256
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0059 0.0109 0.0109
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0051 0.0087 0.0212
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0096 0.021 0.1144
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.005 0.0084 0.1758
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0361
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0049 0.0082 0.0274
Schistosoma mansoni amine GPCR 0.0051 0.0087 0.0087
Schistosoma mansoni amine GPCR 0.0051 0.0087 0.0087
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0054 0.0095 0.0095
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.008 0.008
Mycobacterium tuberculosis Conserved protein 0.0076 0.0156 0.0165
Leishmania major NADH dehydrogenase, putative 0.0033 0.0039 0.0482
Loa Loa (eye worm) hypothetical protein 0.0076 0.0156 0.0852
Echinococcus multilocularis cathepsin L cysteine protease 0.0036 0.0047 0.0046
Echinococcus granulosus beta LACTamase domain containing family member 0.0076 0.0156 0.0155
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0129 0.03 0.0786
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0403 0.1603
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.004 0.0036
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.008 0.008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0005 0.00000000028147
Echinococcus multilocularis neuropeptide s receptor 0.0519 0.1365 0.1364
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0082 0.0172 0.0434
Leishmania major hypothetical protein, conserved 0.0031 0.0032 0.0399
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0087 0.0086
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0038 0.0037
Echinococcus multilocularis allatostatin A receptor 0.0051 0.0087 0.0086
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0044 0.0158
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0062 0.0118 0.0639
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.005 0.0084 0.3323
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0047 0.0132
Mycobacterium leprae PROBABLE THIOSULFATE SULFURTRANSFERASE CYSA2 (RHODANESE-LIKE PROTEIN) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRAN 0.0031 0.0032 0.0067
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase CysA2 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotran 0.0031 0.0032 0.0028
Onchocerca volvulus Neuropeptide F receptor homolog 0.0051 0.0087 0.0398
Leishmania major DNA polymerase kappa, putative 0.0065 0.0124 0.1573
Trypanosoma brucei unspecified product 0.0035 0.0043 0.0534
Loa Loa (eye worm) hypothetical protein 0.0039 0.0054 0.0298
Brugia malayi jmjC domain containing protein 0.021 0.0523 0.2857
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Schistosoma mansoni lipoxygenase 0.0329 0.0847 0.0847
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase SseB 0.0031 0.0032 0.0028
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0051 0.0087 0.0086
Trichomonas vaginalis mercuric reductase, putative 0.0022 0.0008 0.0016
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0118 0.027 0.0269
Echinococcus multilocularis transcription factor Dp 1 0.0044 0.0068 0.0067
Echinococcus granulosus neuropeptide s receptor 0.0519 0.1365 0.1364
Brugia malayi latrophilin 2 splice variant baaae 0.0071 0.0142 0.0773
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0018 0.0092
Plasmodium falciparum glutathione reductase 0.0047 0.0077 0.304
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0082 0.0172 0.0449
Onchocerca volvulus 0.0089 0.0192 0.0901
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Schistosoma mansoni hypothetical protein 0.0028 0.0023 0.0023
Schistosoma mansoni succinate dehydrogenase iron-sulfur protein 0.0028 0.0025 0.0025
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.0014 0.0074
Loa Loa (eye worm) tumor suppressor 0.0327 0.0841 0.4602
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0251 0.0251
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0035 0.0044 0.0043
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0031 0.0032 0.0399
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0054 0.0095 0.0095
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0018 0.0017
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0097 0.0212 0.8413
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0087 0.0086
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0055 0.0099 0.0102
Toxoplasma gondii exonuclease III APE 0.0059 0.0109 0.2291
Loa Loa (eye worm) hypothetical protein 0.0076 0.0156 0.0852
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0087 0.0086
Echinococcus multilocularis muscleblind protein 1 0.0604 0.1598 0.1597
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0054 0.0095 0.0523
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0031 0.0033 0.0029
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0049 0.0082 0.0082
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0087 0.0086
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0022 0.0008 0.0097
Trypanosoma cruzi DNA repair protein, putative 0.0033 0.0037 0.0462
Mycobacterium ulcerans beta-lactamase 0.0076 0.0156 0.0408
Plasmodium falciparum thioredoxin reductase 0.0047 0.0077 0.304
Echinococcus multilocularis protein quaking 0.0028 0.0023 0.0023
Trypanosoma cruzi major cysteine proteinase, putative 0.0109 0.0244 0.31
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0087 0.0086
Mycobacterium ulcerans succinate dehydrogenase iron-sulfur subunit 0.0028 0.0025 0.0063
Schistosoma mansoni hypothetical protein 0.0028 0.0023 0.0023
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0022 0.0008 0.0097
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0099 0.0217 0.1189
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0026 0.0019 0.073
Leishmania major metacaspase, putative 0.0096 0.021 0.2659
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0129 0.03 0.0786
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0048 0.0264
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0177 0.0432 0.0432
Onchocerca volvulus 0.0111 0.0252 0.1189
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0031 0.0032 0.0399
Echinococcus granulosus histone lysine methyltransferase setb 0.0118 0.027 0.0269
Entamoeba histolytica recQ family helicase, putative 0.003 0.0031 0.0068
Brugia malayi Cathepsin L-like precursor 0.0036 0.0047 0.0253
Mycobacterium ulcerans polyketide synthase 0.0077 0.0158 0.0415
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0018 0.0092
Giardia lamblia Kinase, CMGC MAPK 0.0111 0.0251 0.0977
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0054 0.0096 0.1212
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0096
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0251 0.0991
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0047 0.0075 0.0075
Brugia malayi hypothetical protein 0.0035 0.0044 0.0239
Brugia malayi Rhodanese-like domain containing protein 0.0152 0.0363 0.1985
Schistosoma mansoni hypothetical protein 0.0041 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0129
Loa Loa (eye worm) jmjC domain-containing protein 0.021 0.0523 0.286
Schistosoma mansoni ubiquitin-activating enzyme E1C 0.0031 0.0032 0.0032
Echinococcus granulosus cpg binding protein 0.0099 0.0217 0.0216
Schistosoma mansoni histamine h1 receptor 0.0051 0.0087 0.0087
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0049 0.0082 0.1034
Brugia malayi succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0022 0.0007 0.0033
Echinococcus granulosus dna polymerase kappa 0.0108 0.0243 0.0242
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0047 0.0075 0.0076
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0031 0.0032 0.0399
Echinococcus granulosus neuropeptide receptor A26 0.0519 0.1365 0.1364
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0096 0.021 0.4403
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.005 0.0084 0.0847
Toxoplasma gondii PHD-finger domain-containing protein 0.0063 0.0119 0.2494
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0156 0.1972
Loa Loa (eye worm) hypothetical protein 0.0511 0.1342 0.7345
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0054 0.0095 0.0095
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0004 0.0065
Echinococcus multilocularis serotonin receptor 0.0051 0.0087 0.0086
Onchocerca volvulus Cathepsin L homolog 0.0036 0.0047 0.0205
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.0243 0.3079
Brugia malayi Dopamine receptor protein 2 0.0051 0.0087 0.0473
Brugia malayi hypothetical protein 0.0051 0.0087 0.0473
Treponema pallidum ATP-dependent DNA helicase 0.0032 0.0034 0.0105
Schistosoma mansoni cellular tumor antigen P53 0.0107 0.0241 0.0241
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0097 0.0212 0.0227
Trypanosoma cruzi succinate dehydrogenase, putative 0.0033 0.0037 0.0461
Schistosoma mansoni hypothetical protein 0.0041 0.0061 0.0061
Plasmodium vivax rhodanese like protein, putative 0.0031 0.0032 0.1248
Loa Loa (eye worm) steroid hormone receptor 0.0054 0.0095 0.0523
Onchocerca volvulus 0.0025 0.0018 0.0064
Mycobacterium tuberculosis Probable thioesterase TesA 0.0064 0.0123 0.0129
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0099 0.0098
Loa Loa (eye worm) hypothetical protein 0.0073 0.0148 0.081
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0059 0.0109 0.1383
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0031 0.0032 0.0399
Loa Loa (eye worm) TK/ROR protein kinase 0.0021 0.0006 0.0033
Brugia malayi hypothetical protein 0.0051 0.0087 0.0473
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0054 0.0096 0.1212
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.005 0.0085 0.0085
Brugia malayi hypothetical protein 0.0051 0.0087 0.0473
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0203 0.0502 0.0502
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0028 0.0151
Schistosoma mansoni rab6-interacting 0.0111 0.0252 0.0252
Trypanosoma brucei trypanothione reductase 0.0047 0.0077 0.0971
Giardia lamblia Thiosulfate sulfurtransferase 0.0031 0.0032 0.0095
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0005 0.00000000028147
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0024 0.0013 0.0007
Brugia malayi ImpB/MucB/SamB family protein 0.005 0.0085 0.0463
Schistosoma mansoni hypothetical protein 0.0273 0.0692 0.0692
Trypanosoma cruzi succinate dehydrogenase iron-sulfur subunit 0.0028 0.0025 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.021 0.0826
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Echinococcus granulosus caspase 2 0.0185 0.0453 0.0453
Echinococcus granulosus neuropeptide receptor 0.0051 0.0087 0.0086
Echinococcus granulosus Niemann Pick C1 protein 0.0143 0.0339 0.0338
Schistosoma mansoni alpha-glucosidase 0.0143 0.0337 0.0337
Leishmania major cathepsin L-like protease 0.0138 0.0325 0.4127
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0005 0.00000000028147
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0031 0.0032 0.0399
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0044 0.0158
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.005 0.0084 0.0086
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0047 0.0075 0.0196
Brugia malayi CXXC zinc finger family protein 0.0091 0.0198 0.1078
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0031 0.0032 0.0399
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.0243 0.3079
Loa Loa (eye worm) DR-78 0.0025 0.0018 0.0096
Echinococcus multilocularis RUN 0.0111 0.0252 0.0251
Brugia malayi Bloom's syndrome protein homolog 0.0089 0.0192 0.1046
Brugia malayi TAZ zinc finger family protein 0.0113 0.0256 0.1399
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0152 0.0363 0.1444
Onchocerca volvulus 0.0076 0.0156 0.0728
Echinococcus granulosus tumor protein p63 0.0732 0.1947 0.1947
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0325 0.4127
Loa Loa (eye worm) hypothetical protein 0.0049 0.0082 0.0449
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.005 0.0084 0.1758
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0059 0.0109 0.1104
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0217 0.0217
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0059 0.0109 0.0286
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.021 0.0826
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Onchocerca volvulus 0.0134 0.0314 0.149
Brugia malayi sulfakinin receptor protein 0.0051 0.0087 0.0473
Echinococcus multilocularis tissue type plasminogen activator 0.0021 0.0006 0.0005
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0032 0.0035 0.0034
Mycobacterium ulcerans aldehyde dehydrogenase 0.0193 0.0475 0.1249
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0036 0.0047 0.0046
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0217 0.0217
Echinococcus multilocularis beta LACTamase domain containing family member 0.0076 0.0156 0.0155
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0022 0.0008 0.002
Leishmania major eukaryotic translation initiation factor-like 0.0035 0.0044 0.0546
Leishmania major DNA polymerase eta, putative 0.005 0.0085 0.1077
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0096
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Brugia malayi nuclear receptor NHR-88 0.0054 0.0095 0.0519
Plasmodium vivax JmjC domain containing protein 0.0054 0.0096 0.3793
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0008 0.0097
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0022 0.0008 0.002
Trypanosoma cruzi metacaspase, putative 0.0096 0.021 0.2659
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.003 0.0031 0.1208
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.0095 0.0519
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0087 0.0087
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0021 0.0006 0.021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0931 0.2489 1
Mycobacterium leprae conserved hypothetical protein 0.0076 0.0156 0.0393
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0033 0.0039 0.0799
Echinococcus granulosus hypothetical protein 0.0028 0.0023 0.0023
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0095 0.0519
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0054 0.0095 0.0095
Loa Loa (eye worm) cysteine protease 0.0036 0.0047 0.0257
Onchocerca volvulus 0.0025 0.0018 0.0064
Schistosoma mansoni intermediate filament proteins 0.0029 0.0028 0.0028
Brugia malayi Bromodomain containing protein 0.0048 0.008 0.0435
Brugia malayi nuclear receptor NHR-67 0.0025 0.0018 0.0092
Leishmania major cathepsin L-like protease 0.0138 0.0325 0.4127
Onchocerca volvulus 0.0051 0.0087 0.0398
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0018 0.0096
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0084 0.1061
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0051 0.0087 0.0477
Brugia malayi PHD-finger family protein 0.0063 0.0119 0.0648
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0022 0.0008 0.0097
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0062 0.0118 0.0643
Mycobacterium leprae Conserved hypothetical protein 0.112 0.3006 0.7905
Mycobacterium tuberculosis Probable molybdenum cofactor biosynthesis protein MoeB2 (MPT-synthase sulfurylase) (molybdopterin synthase sulphurylase) 0.0031 0.0032 0.0028
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.021 0.0826
Echinococcus granulosus cathepsin l1 0.0024 0.0014 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0142
Schistosoma mansoni Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specificprotein A14 protein) 0.0031 0.0032 0.0032
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0048 0.0138
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0022 0.0008 0.0008
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0455 0.1189 0.1309
Onchocerca volvulus Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial homolog 0.0022 0.0007 0.0012
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0028 0.0147
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0099 0.0098
Mycobacterium ulcerans polyketide synthase 0.0082 0.0172 0.0449
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0273 0.0692 0.0691
Brugia malayi Pre-SET motif family protein 0.01 0.0222 0.1212
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0035 0.0044 0.0546
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0072 0.0145 0.0153
Echinococcus granulosus intermediate filament protein 0.0029 0.0028 0.0027
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0095 0.0095
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase CysA3 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotran 0.0031 0.0032 0.0028
Echinococcus multilocularis sex peptide receptor 0.0051 0.0087 0.0086
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0049 0.0082 0.0312
Schistosoma mansoni jumonji domain containing protein 0.0054 0.0096 0.0096
Echinococcus granulosus lamin dm0 0.0029 0.0028 0.0027
Brugia malayi Protein kinase domain containing protein 0.0021 0.0006 0.0029
Onchocerca volvulus 0.0152 0.0363 0.1725
Brugia malayi Papain family cysteine protease containing protein 0.0036 0.0047 0.0253
Brugia malayi nuclear hormone receptor 0.0025 0.0018 0.0092
Leishmania major hypothetical protein, conserved 0.0031 0.0032 0.0399
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0129 0.03 0.0324
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0051 0.0087 0.0477
Loa Loa (eye worm) PHD-finger family protein 0.0063 0.0119 0.0652
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0455 0.1189 0.3128
Trypanosoma cruzi As/Sb Reductase, putative 0.0031 0.0032 0.0399
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.038 0.0985 1
Brugia malayi Rhodanese-like domain containing protein 0.0031 0.0032 0.0172
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0129 0.03 0.1636
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0099
Trypanosoma brucei glucosidase, putative 0.0037 0.0048 0.0605
Loa Loa (eye worm) glutathione reductase 0.0047 0.0077 0.0422
Brugia malayi Bromodomain containing protein 0.0091 0.0196 0.1071
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Echinococcus granulosus neuropeptide FF receptor 2 0.0051 0.0087 0.0086
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0022 0.0008 0.0161
Schistosoma mansoni hypothetical protein 0.0051 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0061 0.0116 0.0115
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.008 0.044
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.1411 0.38 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0095 0.0523
Onchocerca volvulus Cathepsin L homolog 0.0036 0.0047 0.0205
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3057 0.8296 0.9173
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0018 0.0064
Brugia malayi Pre-SET motif family protein 0.0688 0.1827 1
Trichomonas vaginalis thiosulfate sulfertansferase, putative 0.0031 0.0032 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0641 0.2562
Trypanosoma cruzi trypanothione reductase, putative 0.0022 0.0008 0.0097
Schistosoma mansoni hypothetical protein 0.0089 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Trichomonas vaginalis set domain proteins, putative 0.0783 0.2086 0.8378
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0084 0.0176 0.6998
Echinococcus granulosus sex peptide receptor 0.0051 0.0087 0.0086
Entamoeba histolytica hypothetical protein 0.0035 0.0044 0.0122
Echinococcus granulosus hypothetical protein 0.0051 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0096
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0109 0.0422
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0116 0.0265 0.1448
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0087 0.0087
Echinococcus multilocularis cpg binding protein 0.0099 0.0217 0.0216
Leishmania major 3-mercaptopyruvate sulfurtransferase 0.0031 0.0032 0.0399
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0076 0.0156 0.0852
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0031 0.0032 0.0399
Brugia malayi mbt repeat family protein 0.0049 0.008 0.0436
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0129 0.03 0.03
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0087 0.0086
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0176
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.008 0.008
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0031 0.0032 0.0111
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.005 0.0184
Schistosoma mansoni opsin-like receptor 0.0051 0.0087 0.0087
Schistosoma mansoni amine GPCR 0.0051 0.0087 0.0087
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0018 0.0017
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0054 0.0095 0.0095
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0051 0.0087 0.0477
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Onchocerca volvulus 0.0091 0.0198 0.0929
Entamoeba histolytica rodhanase-like domain containing protein 0.0031 0.0032 0.0072
Schistosoma mansoni lamin 0.0029 0.0028 0.0028
Echinococcus multilocularis FTZ F1 alpha 0.0054 0.0095 0.0095
Leishmania major cathepsin L-like protease 0.0138 0.0325 0.4127
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0048 0.0605
Echinococcus multilocularis protein dispatched 1 0.0049 0.0082 0.0081
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0018 0.0092
Onchocerca volvulus 0.0051 0.0087 0.0398
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0931 0.2489 1
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0129 0.03 0.0299
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0047 0.0171
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0307 0.0787 1
Giardia lamblia Methyltransferase like 2 0.0023 0.0011 0.0012
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0022 0.0008 0.0097
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0051 0.0087 0.0473
Brugia malayi beta-lactamase family protein 0.0076 0.0156 0.0848
Schistosoma mansoni bromodomain containing protein 0.0079 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0111 0.0252 0.1378
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0004 0.004
Mycobacterium tuberculosis Probable lipase LipE 0.0076 0.0156 0.0165
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0087 0.0086
Brugia malayi PHD-finger family protein 0.0028 0.0023 0.0124
Schistosoma mansoni CREB-binding protein 2 0.0113 0.0256 0.0256
Schistosoma mansoni phd/f-box containing protein 0.0054 0.0096 0.0096
Echinococcus multilocularis lipoxygenase domain containing protein 0.0111 0.0252 0.0251
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0142
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0059 0.0109 0.1383
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0029 0.0026 0.0142
Schistosoma mansoni hypothetical protein 0.0063 0.0119 0.0119
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0076 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0028 0.0023 0.0128
Echinococcus multilocularis mitogen activated protein kinase 3 0.0111 0.0251 0.025
Echinococcus granulosus lamin 0.0029 0.0028 0.0027
Echinococcus granulosus jumonji domain containing 1A 0.0054 0.0096 0.0095
Loa Loa (eye worm) MH2 domain-containing protein 0.0125 0.0288 0.1577
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0028 0.0151
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0054 0.0096 0.2007
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.002 0.0019
Onchocerca volvulus 0.0036 0.0047 0.0205
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0156 0.1972
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0325 0.4127
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0106 0.0238 0.0256
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Giardia lamblia PHD finger protein 15 0.0063 0.0119 0.0446
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.005 0.0084 0.0219
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0062 0.0118 0.0117
Leishmania major hypothetical protein, conserved 0.0031 0.0032 0.0399
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) 0.0022 0.0007 0.0006
Echinococcus granulosus allatostatin A receptor 0.0051 0.0087 0.0086
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.005 0.0184
Onchocerca volvulus 0.0783 0.2086 1
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.005 0.0084 0.0847
Leishmania major cathepsin L-like protease 0.0036 0.0047 0.0587
Echinococcus multilocularis lipoxygenase domain containing protein 0.0111 0.0252 0.0251
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0013 0.0065
Treponema pallidum 4'-phosphopantetheinyl transferase 0.005 0.0084 0.0305
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0076 0.0156 0.0852
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0018 0.0018
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0035 0.0044 0.0546
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0054 0.0095 0.0095
Brugia malayi hypothetical protein 0.0089 0.0192 0.1045
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0156 0.1972
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0325 0.4127
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0111 0.0251 0.3181
Mycobacterium tuberculosis Probable oxidoreductase 0.0106 0.0238 0.0256
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0087 0.0087
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0047 0.0047
Schistosoma mansoni jumonji/arid domain-containing protein 0.021 0.0523 0.0523
Onchocerca volvulus 0.0096 0.021 0.0987
Mycobacterium ulcerans aldehyde dehydrogenase 0.0193 0.0475 0.1249
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.0243 0.3079
Brugia malayi Methyltransferase-like protein 4 0.0023 0.0011 0.0058
Schistosoma mansoni caspase-7 (C14 family) 0.0253 0.064 0.064
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0018 0.022
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0176
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0022 0.0008 0.0097
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0051 0.0087 0.0473
Brugia malayi Cathepsin L-like precursor 0.0036 0.0047 0.0253
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0095 0.0207 0.0206
Brugia malayi MAP kinase sur-1 0.0111 0.0251 0.1369
Brugia malayi Doublecortin family protein 0.0111 0.0252 0.1374
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0051 0.0087 0.0087
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0047 0.0075 0.0284
Schistosoma mansoni alpha glucosidase 0.0037 0.0048 0.0048
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0028 0.0025 0.0024
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0018 0.0096
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0008 0.0097
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0027 0.002 0.0015
Loa Loa (eye worm) ctsf protein 0.0036 0.0047 0.0257
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0092 0.1157
Trichomonas vaginalis DNA helicase recq1, putative 0.0089 0.0192 0.0754
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0156 0.0609
Loa Loa (eye worm) thiosulfate sulfurtransferase 0.0031 0.0032 0.0176
Mycobacterium ulcerans aldehyde dehydrogenase 0.0193 0.0475 0.1249
Trichomonas vaginalis DNA polymerase eta, putative 0.0108 0.0243 0.0959
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0038 0.0051 0.0147
Mycobacterium tuberculosis Probable transcriptional regulatory protein 0.0031 0.0032 0.0028
Loa Loa (eye worm) hypothetical protein 0.0053 0.0092 0.0502
Echinococcus multilocularis lamin 0.0029 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0054 0.0095 0.0523
Echinococcus granulosus peregrin 0.0075 0.0152 0.0151
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0072 0.0145 0.0791
Trypanosoma brucei Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0022 0.0007 0.0076
Brugia malayi Thiosulfate sulfurtransferase D2023.5 0.0031 0.0032 0.0172
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0053 0.0093 0.3685
Brugia malayi AF-10 protein 0.002 0.0004 0.0017
Schistosoma mansoni hypothetical protein 0.0031 0.0032 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.0243 0.3079
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.3331 0.9043 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0096 0.021 0.4403
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0076 0.0156 0.0852
Schistosoma mansoni lipoxygenase 0.053 0.1394 0.1394
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0065 0.0357
Mycobacterium leprae PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE) 0.0031 0.0032 0.0067
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Schistosoma mansoni RAR-like nuclear receptor 0.0054 0.0095 0.0095
Entamoeba histolytica hypothetical protein, conserved 0.0031 0.0032 0.0072
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0047 0.0171
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0115 0.0263 0.0283
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0078 0.0078
Brugia malayi nuclear receptor RXR 0.0029 0.0026 0.0137
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0036 0.0047 0.0257
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0636 0.1686 0.1685
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0033 0.0039 0.01
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0156 0.0609
Echinococcus granulosus caspase 8 0.0096 0.021 0.0209
Loa Loa (eye worm) bromodomain containing protein 0.0027 0.0023 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0065 0.0245
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.01 0.0222 0.0221
Trypanosoma cruzi succinate dehydrogenase iron-sulfur subunit 0.0033 0.0037 0.0461
Onchocerca volvulus 0.0152 0.0363 0.1725
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.005 0.1043
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0005 0.00000000028147
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0099 0.0098
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0054 0.0095 0.0095
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0156 0.0609
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0052 0.009 0.188
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0059 0.0109 0.0109
Echinococcus multilocularis JmjC domain containing protein 4 0.0054 0.0096 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0054 0.0095 0.0523
Echinococcus granulosus 7TM GPCR rhodopsin 0.0051 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0054 0.0096 0.0525
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Echinococcus granulosus mixed lineage leukemia protein mll 0.0026 0.002 0.0019
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0047 0.0075 0.0411
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0018 0.0018
Giardia lamblia Hypothetical protein 0.0031 0.0032 0.0095
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0156 0.6172
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0087 0.0086
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0051 0.0087 0.0086
Echinococcus granulosus alpha 1A adrenergic receptor 0.0051 0.0087 0.0086
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0156 0.0156
Toxoplasma gondii type I fatty acid synthase, putative 0.0082 0.0172 0.3599
Brugia malayi hypothetical protein 0.0029 0.0026 0.0137
Mycobacterium tuberculosis Probable esterase LipL 0.0076 0.0156 0.0165
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0156 0.0609
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0048 0.0605
Plasmodium falciparum mitogen-activated protein kinase phosphatase 1, putative 0.0031 0.0032 0.1248
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0018 0.0017
Onchocerca volvulus Cell death protein 3 homolog 0.0185 0.0453 0.2158
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0097 0.0212 0.4451
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0018 0.0017
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0013 0.0492
Onchocerca volvulus 0.0051 0.0087 0.0398
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0068 0.0133 0.1681
Mycobacterium tuberculosis Possible transcriptional regulatory protein (possibly ArsR-family) 0.0031 0.0032 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0054 0.0095 0.0523
Echinococcus multilocularis apoptotic protease activating factor 1 0.0089 0.0192 0.0191
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0018 0.0092
Giardia lamblia Dual specificity phosphatase Cdc25, putative 0.0031 0.0032 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0054 0.0095 0.0523
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.005 0.0049
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0051 0.0087 0.0477
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0032 0.0111
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0145 0.0345 0.4378
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.0151
Onchocerca volvulus 0.0511 0.1342 0.6426
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0054 0.0095 0.0095
Leishmania major phosphopantetheinyl transferase-like protein 0.005 0.0084 0.1061
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0032 0.0111
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0031 0.0032 0.0032
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0048 0.1002
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.008 0.008
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0152 0.0363 0.1444
Treponema pallidum exodeoxyribonuclease (exoA) 0.0059 0.0109 0.0407
Brugia malayi hypothetical protein 0.0511 0.1342 0.7344
Echinococcus granulosus lysine specific demethylase 5A 0.021 0.0523 0.0522
Trypanosoma cruzi metacaspase, putative 0.0096 0.021 0.2659
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0018 0.0017
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0077 0.0158 0.0168
Loa Loa (eye worm) jmjC domain-containing protein 0.0054 0.0096 0.0525
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.0243 0.3079
Echinococcus granulosus expressed protein 0.0039 0.0053 0.0052
Plasmodium falciparum cysteine repeat modular protein 1 0.0021 0.0006 0.021
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0068 0.0133 0.1681
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Brugia malayi Cathepsin L-like precursor 0.0024 0.0014 0.0074
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0054 0.0095 0.0095
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0062 0.0118 0.4652
Echinococcus granulosus succinate dehydrogenase (ubiquinone) iron sulfur 0.0051 0.0087 0.0086
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0065 0.0124 0.013
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0152 0.0363 0.0363
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0076 0.0156 0.0165
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0034 0.0428
Schistosoma mansoni zinc finger protein 0.0035 0.0042 0.0042
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.0221 0.0221
Schistosoma mansoni hypothetical protein 0.0111 0.0252 0.0252
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0077 0.0158 0.04
Mycobacterium tuberculosis Probable succinate dehydrogenase (iron-sulphur protein subunit) SdhB (succinic dehydrogenase) (fumarate reductase) (fumarate deh 0.0028 0.0025 0.002
Onchocerca volvulus 0.0036 0.0047 0.0205
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0054 0.0095 0.0095
Chlamydia trachomatis recombinase RecA 0.0106 0.0238 0.2405
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0061 0.0116 0.0115
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0051 0.0087 0.0087
Echinococcus multilocularis jumonji domain containing 1A 0.0054 0.0096 0.0095
Echinococcus multilocularis g-protein coupled receptor 0.0051 0.0087 0.0086
Onchocerca volvulus 0.0051 0.0087 0.0398
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0099 0.0099
Schistosoma mansoni cpg binding protein 0.0099 0.0217 0.0217
Mycobacterium ulcerans Type I modular polyketide synthase 0.0077 0.0158 0.0415
Plasmodium falciparum LCCL domain-containing protein 0.0111 0.0252 1
Brugia malayi Thioredoxin reductase 0.0047 0.0077 0.0418
Schistosoma mansoni hypothetical protein 0.0307 0.0786 0.0786
Schistosoma mansoni coup transcription factor 0.0054 0.0095 0.0095
Echinococcus multilocularis dnaJ subfamily B 0.1302 0.3504 0.3503
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0641 0.2562
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0143
Trichomonas vaginalis cdc25b, putative 0.0152 0.0363 0.1444
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.021 0.0826
Echinococcus granulosus Rhodanese 0.0031 0.0032 0.0031
Brugia malayi hypothetical protein 0.0025 0.0018 0.0092
Onchocerca volvulus 0.0031 0.0032 0.0134
Trypanosoma brucei succinate dehydrogenase iron-sulfur subunit 0.0028 0.0025 0.0306
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0026 0.0137
Brugia malayi Serotonin receptor 0.0051 0.0087 0.0473
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0018 0.069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0087 0.0087
Giardia lamblia Kinase, STE STE20 0.0076 0.0156 0.0596
Onchocerca volvulus 0.0051 0.0087 0.0398
Echinococcus granulosus succinate dehydrogenase ubiquinone 0.0022 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0096
Loa Loa (eye worm) inositol-1 0.0037 0.005 0.0275
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0152 0.0363 0.1988
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0059 0.0109 0.0114
Echinococcus granulosus expressed conserved protein 0.0094 0.0205 0.0204
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0065 0.0064
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0004 0.0065
Echinococcus multilocularis caspase 3 0.0158 0.0378 0.0378
Echinococcus granulosus cathepsin L cysteine proteinase 0.0036 0.0047 0.0046
Onchocerca volvulus Alhambra homolog 0.0063 0.0119 0.0552
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0111 0.0251 0.1372
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0142
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0403 0.1603
Schistosoma mansoni hypothetical protein 0.0033 0.0038 0.0038
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0118 0.027 0.1475
Entamoeba histolytica rodhanase-like domain containing protein 0.0152 0.0363 0.141
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0022 0.0008 0.0305
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0049 0.0082 0.0081
Schistosoma mansoni hypothetical protein 0.0033 0.0038 0.0038
Loa Loa (eye worm) succinate dehydrogenase iron-sulfur protein 0.0051 0.0087 0.0476
Onchocerca volvulus 0.0029 0.0028 0.0112
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0049 0.0082 0.1034
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0028 0.0025 0.0025
Echinococcus granulosus caspase 0.0253 0.064 0.0639
Mycobacterium ulcerans thiosulfate sulfurtransferase, CysA2 0.0031 0.0032 0.0082
Onchocerca volvulus 0.0036 0.0047 0.0205
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0039 0.0054 0.1129
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0403 0.1603
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0038 0.0051 0.0634
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0427 0.1701
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0082 0.0172 0.0449
Trypanosoma brucei succinate dehydrogenase iron-sulfur subunit, putative 0.0033 0.0037 0.0461
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0156 0.0156
Mycobacterium ulcerans hypothetical protein 0.0031 0.0032 0.0082
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0156 0.1972
Loa Loa (eye worm) hypothetical protein 0.005 0.0085 0.0467
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.005 0.063
Loa Loa (eye worm) hypothetical protein 0.01 0.0221 0.1211
Echinococcus multilocularis succinate dehydrogenase iron sulfur protein 0.0028 0.0025 0.0024
Brugia malayi intermediate filament protein 0.0029 0.0028 0.0147
Echinococcus multilocularis musashi 0.0029 0.0028 0.0027
Trypanosoma cruzi NADH dehydrogenase, putative 0.0033 0.0039 0.0482
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0054 0.0095 0.0519
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0019 0.0001 0.0004
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0455 0.1189 0.3117
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0203 0.0502 0.0502
Loa Loa (eye worm) hypothetical protein 0.0177 0.0432 0.2366
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0106 0.0238 0.2405
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0047 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0059 0.0109 0.0594
Mycobacterium leprae Probable succinate dehydrogenase (iron-sulfur protein subunit) SdhB (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHY 0.0028 0.0025 0.0048
Loa Loa (eye worm) hypothetical protein 0.0121 0.0279 0.1527
Echinococcus multilocularis bloom syndrome protein 0.0089 0.0192 0.0191
Schistosoma mansoni DNA helicase recq1 0.0062 0.0118 0.0118
Plasmodium vivax vivapain-2 0.0036 0.0047 0.1839
Echinococcus multilocularis dna polymerase kappa 0.0108 0.0243 0.0242
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3379 0.9174 0.9174
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0036 0.0047 0.0171
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0022 0.0008 0.0008
Echinococcus granulosus PHD finger protein rhinoceros 0.0063 0.0119 0.0118
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Plasmodium falciparum thioredoxin reductase 0.0022 0.0008 0.0305
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0029 0.0026 0.0026
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0038 0.0051 0.0634
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0087 0.0477
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0018 0.0018
Brugia malayi Rhodanese-like domain containing protein 0.0152 0.0363 0.1985
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0931 0.2489 1
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0082 0.0172 0.0182
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0688 0.1827 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0054 0.0095 0.0095
Trichomonas vaginalis cdc25b, putative 0.0152 0.0363 0.1444
Loa Loa (eye worm) hypothetical protein 0.0604 0.1598 0.8746
Loa Loa (eye worm) jmjC domain-containing protein 0.0054 0.0096 0.0525
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0087 0.0087
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.0221 0.0221
Schistosoma mansoni adenoreceptor 0.0051 0.0087 0.0087
Giardia lamblia Hypothetical protein 0.0031 0.0032 0.0095
Trypanosoma brucei DNA polymerase IV, putative 0.0108 0.0243 0.3079
Echinococcus granulosus dnaJ subfamily B 0.1302 0.3504 0.3503
Echinococcus multilocularis lysine specific demethylase 6a 0.0054 0.0096 0.0095
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0047 0.0171
Mycobacterium ulcerans thiosulfate sulfurtransferase SseA 0.0031 0.0032 0.0082
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.021 0.0826
Schistosoma mansoni ap endonuclease 0.0059 0.0109 0.0109
Schistosoma mansoni hypothetical protein 0.0041 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0096
Brugia malayi RIKEN cDNA 4930451A13 0.0031 0.0032 0.0172
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0077 0.0158 0.0863
Mycobacterium tuberculosis Probable dehydrogenase 0.0097 0.0212 0.0227
Onchocerca volvulus 0.0031 0.0032 0.0134
Echinococcus multilocularis PHD finger protein rhinoceros 0.0063 0.0119 0.0118
Loa Loa (eye worm) hypothetical protein 0.0043 0.0065 0.0357
Onchocerca volvulus 0.0051 0.0087 0.0398
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0075 0.0154 0.0153
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0035 0.0044 0.0044
Echinococcus granulosus caspase 3 0.0158 0.0378 0.0378
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0048 0.0138
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0077 0.0078
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0044 0.0158
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0166 0.04 0.2191
Onchocerca volvulus 0.0051 0.0087 0.0398
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0035 0.0044 0.0546
Brugia malayi polk-prov protein 0.0073 0.0148 0.0806
Schistosoma mansoni Replicative DNA helicase 0.038 0.0985 0.0985
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0047 0.0075 0.296
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0082 0.0172 0.0434
Brugia malayi jmjC domain containing protein 0.0054 0.0096 0.0521
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0032 0.0035 0.0034
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0044 0.0044
Loa Loa (eye worm) MBCTL1 0.0055 0.0099 0.054
Leishmania major hypothetical protein, conserved 0.0023 0.0011 0.0135
Schistosoma mansoni methyltransferase-related 0.0023 0.0011 0.0011
Wolbachia endosymbiont of Brugia malayi succinate dehydrogenase iron-sulfur subunit 0.0051 0.0087 0.0875
Onchocerca volvulus Bile acid receptor homolog 0.0054 0.0095 0.0438
Echinococcus granulosus geminin 0.0169 0.0409 0.0408
Schistosoma mansoni blooms syndrome DNA helicase 0.0032 0.0034 0.0034
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0036 0.0047 0.0046
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0035 0.0044 0.0043
Plasmodium vivax iron-sulfur subunit of succinate dehydrogenase, putative 0.0051 0.0087 0.3431
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0251 0.3181
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0325 0.4127
Echinococcus multilocularis Rhodanese 0.0031 0.0032 0.0031
Plasmodium falciparum rhodanese like protein, putative 0.0031 0.0032 0.1248
Mycobacterium tuberculosis Probable fumarate reductase [iron-sulfur subunit] FrdB (fumarate dehydrogenase) (fumaric hydrogenase) 0.0028 0.0025 0.002
Brugia malayi hypothetical protein 0.0026 0.0018 0.0095
Plasmodium vivax metacaspase 1, putative 0.0096 0.021 0.8324
Brugia malayi tumor suppressor. 0.0327 0.0841 0.46
Schistosoma mansoni retinoic acid receptor RXR 0.0054 0.0095 0.0095
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0109 0.0422
Loa Loa (eye worm) hypothetical protein 0.0032 0.0034 0.0188
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0062 0.0118 0.0117
Trypanosoma cruzi DNA polymerase kappa, putative 0.0108 0.0243 0.3079
Schistosoma mansoni succinate dehydrogenase iron-sulfur protein 0.0051 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0206
Loa Loa (eye worm) hypothetical protein 0.0054 0.0095 0.0523
Echinococcus granulosus g protein coupled receptor 0.0051 0.0087 0.0086
Echinococcus multilocularis mitogen activated protein kinase 0.0111 0.0251 0.025
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.0095 0.0519
Mycobacterium tuberculosis Probable reductase 0.0097 0.0212 0.0227
Toxoplasma gondii kringle domain-containing protein 0.0021 0.0006 0.0111
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Echinococcus multilocularis dual specificity mitogen activated protein 0.0076 0.0156 0.0156
Onchocerca volvulus 0.01 0.0222 0.1047
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0054 0.0095 0.0519
Schistosoma mansoni hypothetical protein 0.0071 0.0142 0.0142
Brugia malayi G-protein coupled receptor 0.0051 0.0087 0.0473
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0036 0.0047 0.1839
Echinococcus granulosus serotonin receptor 0.0051 0.0087 0.0086
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0033 0.0039 0.151
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0176
Echinococcus multilocularis neuropeptide receptor A26 0.0519 0.1365 0.1364
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0087 0.0086
Brugia malayi hypothetical protein 0.0028 0.0024 0.0124
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0096 0.021 0.021
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0054 0.0095 0.0095
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0325 0.4127
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0142
Loa Loa (eye worm) hypothetical protein 0.0062 0.0118 0.0643
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0029 0.0026 0.0025
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0051 0.0087 0.0086
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0077 0.304
Giardia lamblia Fructose-bisphosphate aldolase 0.0931 0.2489 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0054 0.0095 0.0438
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0082 0.1031
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0033 0.0039 0.0799
Mycobacterium ulcerans polyketide synthase Pks9 0.0051 0.0087 0.0227
Mycobacterium ulcerans Type I modular polyketide synthase 0.0077 0.0158 0.0415
Loa Loa (eye worm) hypothetical protein 0.0089 0.0192 0.1049
Schistosoma mansoni patched 1 0.0043 0.0065 0.0065
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.008 0.008
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0082 0.0172 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.021 0.0826
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0005 0.00000000028147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Mycobacterium ulcerans polyketide synthase MbtD 0.0024 0.0013 0.0031
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0087 0.0087
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.005 0.013
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0176
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0333 0.0857 0.0856
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0087 0.0087
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0051 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0142
Brugia malayi ImpB/MucB/SamB family protein 0.005 0.0085 0.0463
Entamoeba histolytica hypothetical protein 0.0031 0.0032 0.0072
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0038 0.0202
Echinococcus multilocularis GPCR, family 2 0.0033 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0055 0.0099 0.054
Onchocerca volvulus 0.0051 0.0087 0.0398
Trichomonas vaginalis STE family protein kinase 0.0076 0.0156 0.0611
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0022 0.0008 0.0305
Plasmodium falciparum cysteine proteinase falcipain 3 0.0036 0.0047 0.1839
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0033
Plasmodium vivax SET domain protein, putative 0.01 0.0222 0.8821
Onchocerca volvulus 0.0051 0.0087 0.0398
Loa Loa (eye worm) transcription factor SMAD2 0.0125 0.0288 0.1577
Entamoeba histolytica acetyltransferase, GNAT family 0.0085 0.0179 0.0668
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0054 0.0095 0.0523
Trichomonas vaginalis STE family protein kinase 0.0076 0.0156 0.0611
Brugia malayi mbt repeat family protein 0.0049 0.008 0.0436
Plasmodium falciparum metacaspase-like protein 0.0096 0.021 0.8324
Brugia malayi G-protein coupled receptor 0.0051 0.0087 0.0473
Echinococcus granulosus muscleblind protein 0.0604 0.1598 0.1597
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0054 0.0096 0.0096
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0217 0.0217
Plasmodium vivax multidomain scavenger receptor, putative 0.0111 0.0252 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0039 0.0053 0.029
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0051 0.0087 0.0087
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0038 0.0206
Schistosoma mansoni loxhd1 0.0111 0.0252 0.0252
Echinococcus granulosus transcription factor Dp 1 0.0044 0.0068 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0054 0.0095 0.0519
Plasmodium falciparum histone acetyltransferase GCN5 0.0085 0.0179 0.7117
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0075 0.0152 0.0161
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0062 0.0118 0.0117
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0051 0.0087 0.0398
Echinococcus granulosus orexin receptor type 2 0.0051 0.0087 0.0086
Schistosoma mansoni protein kinase 0.0076 0.0156 0.0156
Schistosoma mansoni hypothetical protein 0.0021 0.0005 0.0005
Leishmania major cysteine peptidase A (CPA) 0.0036 0.0047 0.0587
Onchocerca volvulus 0.0051 0.0087 0.0398
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0145 0.0788
Mycobacterium ulcerans hypothetical protein 0.0162 0.039 0.1024
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0129 0.03 0.0299
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0109 0.433
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0032 0.0111
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0931 0.2489 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Brugia malayi Cathepsin L-like precursor 0.0036 0.0047 0.0253
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.01 0.0222 0.0222
Brugia malayi Temporarily assigned gene name protein 44 0.0028 0.0024 0.0124
Schistosoma mansoni biogenic amine receptor 0.0051 0.0087 0.0087
Brugia malayi jmjC domain containing protein 0.0054 0.0096 0.0521
Loa Loa (eye worm) jmjC domain-containing protein 0.0054 0.0096 0.0525
Echinococcus granulosus ubiquitin specific protease 41 0.0049 0.0082 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.021 0.0826
Loa Loa (eye worm) translation initiation factor 4E 0.0035 0.0044 0.0239
Plasmodium vivax hypothetical protein, conserved 0.0096 0.021 0.8324
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Echinococcus granulosus g protein coupled receptor 0.0051 0.0087 0.0086
Brugia malayi hypothetical protein 0.0111 0.0252 0.1374
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0087 0.0477
Entamoeba histolytica rodhanase-like domain containing protein 0.0031 0.0032 0.0072
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0051 0.0087 0.0086
Brugia malayi beta-lactamase 0.0076 0.0156 0.0848
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0078
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0047 0.0075 0.0246
Loa Loa (eye worm) acyl carrier protein 0.0035 0.0045 0.0245
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0156 0.0609
Mycobacterium leprae Conserved hypothetical protein 0.0031 0.0032 0.0067
Schistosoma mansoni aldehyde dehydrogenase 0.0193 0.0475 0.0475
Echinococcus multilocularis Polycystic kidney disease protein 0.0111 0.0252 0.0251
Trypanosoma cruzi cruzipain precursor, putative 0.0138 0.0325 0.4127
Brugia malayi neuropeptide F receptor 0.0051 0.0087 0.0473
Schistosoma mansoni alpha-1 adrenergic receptor 0.0051 0.0087 0.0087
Onchocerca volvulus 0.0111 0.0252 0.1189
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0062 0.0118 0.0117
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0018 0.0017
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0018 0.022
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.04 0.04
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0641 0.2562
Loa Loa (eye worm) hypothetical protein 0.0511 0.1342 0.7345
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0177 0.0432 0.2363
Schistosoma mansoni opsin-like receptor 0.0051 0.0087 0.0087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0047 0.0171
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0047 0.0075 0.0246
Brugia malayi hypothetical protein 0.0051 0.0087 0.0473
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0087 0.0087
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0254 0.0641 0.3505
Schistosoma mansoni nuclear hormone receptor 0.0054 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0096 0.021 0.1148
Schistosoma mansoni succinate dehydrogenase 0.0022 0.0007 0.0007
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0077 0.0422
Echinococcus multilocularis tRNA 2 selenouridine synthase 0.0031 0.0032 0.0031
Entamoeba histolytica hypothetical protein 0.0035 0.0044 0.0122
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0076 0.0156 0.0855
Leishmania major cathepsin L-like protease 0.0036 0.0047 0.0587
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0087 0.0086
Trypanosoma cruzi DNA polymerase eta, putative 0.005 0.0085 0.1077
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.0221 0.0837
Loa Loa (eye worm) TYRA-2 protein 0.0051 0.0087 0.0477
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0087 0.0086
Schistosoma mansoni hypothetical protein 0.0636 0.1686 0.1686
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0054 0.0096 0.1212
Entamoeba histolytica rodhanase-like domain containing protein 0.0031 0.0032 0.0072
Mycobacterium leprae Probable lipase LipE 0.0076 0.0156 0.0393
Schistosoma mansoni alpha-glucosidase 0.0143 0.0337 0.0337
Plasmodium falciparum glutathione reductase 0.0022 0.0008 0.0305
Brugia malayi steroid hormone receptor 0.0054 0.0095 0.0519
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0124 0.1573
Leishmania major trypanothione reductase 0.0047 0.0077 0.0971
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0403 0.1603
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0047 0.0171
Echinococcus multilocularis Niemann Pick C1 protein 0.0143 0.0339 0.0338
Loa Loa (eye worm) hypothetical protein 0.013 0.0302 0.165
Brugia malayi neuropeptide F receptor 0.0051 0.0087 0.0473
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0096
Chlamydia trachomatis replicative DNA helicase 0.038 0.0985 1
Leishmania major hypothetical protein, conserved 0.0021 0.0006 0.0067
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Loa Loa (eye worm) twinkle helicase 0.0109 0.0244 0.1337
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0099 0.0217 0.1185
Onchocerca volvulus 0.0021 0.0006 0.0009
Chlamydia trachomatis hypothetical protein 0.0031 0.0032 0.0318
Echinococcus granulosus fmrfamide receptor 0.0051 0.0087 0.0086
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1364 0.3673 0.4057
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0005 0.0029
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0051 0.0087 0.0087
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0087 0.0086
Mycobacterium leprae Probable polyketide synthase Pks1 0.0082 0.0172 0.0434
Echinococcus granulosus zinc finger protein 0.0035 0.0042 0.0042
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0034 0.0708
Echinococcus granulosus Polycystic kidney disease protein 0.0111 0.0252 0.0251
Brugia malayi F/Y-rich N-terminus family protein 0.0054 0.0095 0.0518
Brugia malayi hypothetical protein 0.0111 0.0252 0.1374
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0054 0.0095 0.0519
Loa Loa (eye worm) hypothetical protein 0.0054 0.0095 0.0523
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.005 0.0049
Schistosoma mansoni hypothetical protein 0.0636 0.1686 0.1686
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0066 0.0828
Loa Loa (eye worm) hypothetical protein 0.0054 0.0095 0.0523
Echinococcus granulosus somatostatin receptor 0.0051 0.0087 0.0086
Trypanosoma brucei DNA polymerase IV, putative 0.0094 0.0204 0.2582
Trypanosoma cruzi DNA polymerase kappa, putative 0.0108 0.0243 0.3079
Echinococcus granulosus lysosomal alpha glucosidase 0.0166 0.04 0.04
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Echinococcus multilocularis cysteine protease 0.0036 0.0047 0.0046
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0048 0.0047
Mycobacterium tuberculosis Probable lipase LipD 0.0076 0.0156 0.0165
Mycobacterium ulcerans recombinase A 0.0106 0.0238 0.0623
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.0095 0.0519
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0039 0.0053 0.0286
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.005 0.0084 0.1765
Onchocerca volvulus 0.0036 0.0047 0.0205
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0087 0.0086
Brugia malayi Cathepsin L-like precursor 0.0024 0.0014 0.0074
Loa Loa (eye worm) hypothetical protein 0.0185 0.0453 0.2482
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0117 0.0269 0.029
Schistosoma mansoni zinc finger protein 0.0025 0.0018 0.0018
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0031 0.0032 0.0399
Onchocerca volvulus 0.0054 0.0095 0.0438
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0047 0.0075 0.0945
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0087 0.0086
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0051 0.0087 0.0086
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0051 0.0087 0.0086
Echinococcus multilocularis ubiquitin specific protease 41 0.0049 0.0082 0.0081
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0095 0.0095
Loa Loa (eye worm) melatonin receptor type 1A 0.0051 0.0087 0.0477
Brugia malayi GnHR receptor homolog 0.0051 0.0087 0.0473
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0022 0.0008 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0005 0.00000000028147
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0049 0.0082 0.1034
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0048 0.0176
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0063 0.0119 0.0119
Schistosoma mansoni jumonji/arid domain-containing protein 0.021 0.0523 0.0523
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.005 0.0084 0.0219
Echinococcus granulosus g-protein coupled receptor 0.0051 0.0087 0.0086
Brugia malayi Dopamine receptor protein 1 0.0051 0.0087 0.0473
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0047 0.0171
Schistosoma mansoni inositol monophosphatase 0.0037 0.005 0.005
Trichomonas vaginalis Phage shock protein E precursor, putative 0.0031 0.0032 0.0111
Schistosoma mansoni DNA polymerase eta 0.005 0.0085 0.0085
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0026 0.002 0.0019
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0024 0.0014 0.0008
Echinococcus multilocularis caspase 8 0.0096 0.021 0.0209
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0062 0.0118 0.0639
Plasmodium falciparum metacaspase 1 0.0096 0.021 0.8324
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0217 0.0217
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0049 0.0082 0.1034
Schistosoma mansoni dual specificity protein phosphatase 0.004 0.0056 0.0056
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0141 0.0334 0.1829
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0032 0.0111
Mycobacterium leprae Polyketide synthase Pks13 0.0115 0.0263 0.0674
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0087 0.0086
Leishmania major cathepsin L-like protease 0.0036 0.0047 0.0587
Echinococcus multilocularis tumor protein p63 0.0732 0.1947 0.1947
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.005 0.0184
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0251 0.0991
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0035 0.0044 0.0044
Toxoplasma gondii PHD-finger domain-containing protein 0.0063 0.0119 0.2494
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0119 0.4714
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.0243 0.3079
Schistosoma mansoni cpg binding protein 0.0091 0.0198 0.0198
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0273 0.0692 0.0691
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0075 0.0152 0.0161
Schistosoma mansoni caspase-3 (C14 family) 0.0253 0.064 0.064
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0096 0.021 0.4403
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0022 0.0008 0.0097
Echinococcus granulosus lysine specific demethylase 6a 0.0054 0.0096 0.0095
Loa Loa (eye worm) hypothetical protein 0.0054 0.0095 0.0523
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0011 0.0028
Echinococcus granulosus mitogen activated protein kinase 0.0111 0.0251 0.025
Echinococcus granulosus lipoxygenase domain containing protein 0.0111 0.0252 0.0251
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0018 0.0064
Brugia malayi putative neuropeptide receptor NPR1 0.0051 0.0087 0.0473
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.002 0.0019
Plasmodium vivax glutathione reductase, putative 0.0047 0.0077 0.304
Schistosoma mansoni rab6-interacting 0.0111 0.0252 0.0252
Echinococcus multilocularis serotonin receptor 0.0051 0.0087 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.0243 0.3079
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0048 0.0176
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0076 0.0156 0.0848
Entamoeba histolytica cysteine protease, putative 0.0036 0.0047 0.0132
Brugia malayi photoreceptor-specific nuclear receptor 0.0054 0.0095 0.0519
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0054 0.0095 0.0095
Loa Loa (eye worm) runx1 0.0064 0.0123 0.0672
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.005 0.0085 0.0467
Brugia malayi Steroid receptor seven-up type 2 0.0054 0.0095 0.0519
Schistosoma mansoni steroid hormone receptor ad4bp 0.0054 0.0095 0.0095
Mycobacterium leprae conserved hypothetical protein 0.005 0.0084 0.0204
Echinococcus granulosus fetal alzheimer antigen falz 0.0028 0.0025 0.0024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0931 0.2489 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0048 0.0047
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0059 0.0109 0.0407
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.021 0.0826
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.0095 0.0519
Brugia malayi hypothetical protein 0.0029 0.0026 0.0137
Entamoeba histolytica hypothetical protein 0.0035 0.0044 0.0122
Onchocerca volvulus 0.0072 0.0145 0.0674
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0044 0.0068 0.0067
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0018 0.0092
Loa Loa (eye worm) doublecortin family protein 0.0111 0.0252 0.1378
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0004 0.004
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0026 0.0137
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1411 0.38 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0018 0.0017
Brugia malayi Kringle domain containing protein 0.0021 0.0006 0.0029
Echinococcus multilocularis peregrin 0.0075 0.0152 0.0151
Echinococcus multilocularis ecdysone induced protein 78C 0.0054 0.0095 0.0095
Onchocerca volvulus Cathepsin F homolog 0.0036 0.0047 0.0205
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0111 0.0251 0.3181
Echinococcus multilocularis geminin 0.0169 0.0409 0.0408
Schistosoma mansoni opsin-like receptor 0.0051 0.0087 0.0087
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0095 0.0095
Onchocerca volvulus Glucosylceramidase homolog 0.0167 0.0403 0.1914
Entamoeba histolytica rodhanase-like domain containing protein 0.0152 0.0363 0.141
Entamoeba histolytica recQ family DNA helicase 0.0032 0.0034 0.0082
Loa Loa (eye worm) hypothetical protein 0.0072 0.0144 0.079
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0641 0.2562
Schistosoma mansoni neuropeptide receptor 0.0051 0.0087 0.0087
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0097 0.0212 0.4451
Echinococcus granulosus dna polymerase eta 0.005 0.0085 0.0085
Brugia malayi MoeZ/MoeB domain containing protein 0.0031 0.0032 0.0172
Echinococcus granulosus CREB binding protein 0.0113 0.0256 0.0256
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0048 0.0048
Brugia malayi conserved hypotetical protein 0.0025 0.0018 0.0092
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0051 0.0087 0.0473
Loa Loa (eye worm) fibroinase 0.0036 0.0047 0.0257
Trypanosoma cruzi mercaptopyruvate sulfurtransferase, putative 0.0031 0.0032 0.0399
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0087 0.0086
Brugia malayi hypothetical protein 0.0051 0.0087 0.0473
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0039
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0034 0.0428
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0111 0.0251 0.3181
Mycobacterium tuberculosis Probable hydrolase 0.0076 0.0156 0.0165
Trichomonas vaginalis DNA helicase recq, putative 0.0068 0.0133 0.0517
Onchocerca volvulus 0.0049 0.008 0.0366
Onchocerca volvulus 0.0076 0.0156 0.0728
Brugia malayi RE15519p 0.0051 0.0087 0.0473
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0008 0.0097
Leishmania major eukaryotic translation initiation factor-like protein 0.0035 0.0044 0.0546
Entamoeba histolytica hypothetical protein 0.0031 0.0032 0.0072
Plasmodium falciparum iron-sulfur subunit of succinate dehydrogenase 0.0051 0.0087 0.3431
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0047 0.0075 0.0074
Trichomonas vaginalis STE family protein kinase 0.0076 0.0156 0.0611
Chlamydia trachomatis succinate dehydrogenase iron sulfur subunit 0.0028 0.0025 0.0244
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0018 0.0017
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0076 0.0156 0.0165
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0078
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0076 0.0156 0.0851
Echinococcus granulosus tissue type plasminogen activator 0.0021 0.0006 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0148 0.1873
Loa Loa (eye worm) hypothetical protein 0.0071 0.0142 0.0776
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Treponema pallidum recombinase A 0.0106 0.0238 0.0924
Trypanosoma cruzi DNA polymerase kappa, putative 0.0108 0.0243 0.3079
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0333 0.0857 0.0856
Loa Loa (eye worm) hypothetical protein 0.0076 0.0156 0.0852
Brugia malayi succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0022 0.0007 0.0033
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0097 0.0212 0.0835
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0087 0.0086
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0087 0.0086
Schistosoma mansoni thyroid hormone receptor 0.0327 0.084 0.084
Onchocerca volvulus 0.0051 0.0087 0.0398
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.005 0.063
Loa Loa (eye worm) acetyltransferase 0.0319 0.0818 0.4477
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0146 0.0347 0.1895
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0096
Loa Loa (eye worm) RecQ helicase 0.0089 0.0192 0.1049
Echinococcus multilocularis centrosomal protein of 41 kDa 0.0031 0.0032 0.0031
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.005 0.0503
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.0095 0.0519
Brugia malayi Glycosyl hydrolases family 31 protein 0.0166 0.04 0.2188
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0087 0.0086
Schistosoma mansoni ubiquitin-activating enzyme E1 0.0031 0.0032 0.0032
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0044 0.0158
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0048 0.0176
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0109 0.433
Brugia malayi ORL1-like opioid receptor 0.0051 0.0087 0.0473
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0049 0.0082 0.0445
Mycobacterium tuberculosis Hypothetical protein 0.0023 0.0011 0.0005
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0254 0.0641 0.3508
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0065 0.0124 0.1573
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0008 0.0097
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0049 0.0082 0.0297
Onchocerca volvulus 0.0051 0.0087 0.0398
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.053 0.1394 0.1393
Leishmania major hypothetical protein, conserved 0.0031 0.0032 0.0399
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0049 0.0082 0.0081
Schistosoma mansoni hypothetical protein 0.0041 0.0061 0.0061
Echinococcus granulosus lipoxygenase domain containing protein 0.0111 0.0252 0.0251
Treponema pallidum replicative DNA helicase (dnaB) 0.038 0.0985 0.3937
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0082 0.1031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0047 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.021 0.0826
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0036 0.0047 0.0257
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0006 0.0067
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0217 0.0217
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) iron sulfur 0.0051 0.0087 0.0086
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0051 0.0087 0.0477
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0049 0.0082 0.0081
Mycobacterium tuberculosis Conserved protein 0.0076 0.0156 0.0165
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0403 0.1603
Schistosoma mansoni hypothetical protein 0.0051 0.0087 0.0087
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0048 0.0176
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0087 0.0477
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0047 0.0075 0.0269
Trypanosoma cruzi Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0022 0.0007 0.0076
Schistosoma mansoni polycystin 1-related 0.0111 0.0252 0.0252
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0106 0.0238 0.0608
Trypanosoma brucei Metacaspase-4 0.0096 0.021 0.2659
Brugia malayi Tachykinin-like peptides receptor 99D 0.0051 0.0087 0.0473
Plasmodium falciparum phd finger protein, putative 0.0063 0.0119 0.4714
Schistosoma mansoni hypothetical protein 0.0031 0.0032 0.0032
Schistosoma mansoni lozenge 0.0064 0.0123 0.0123
Echinococcus granulosus GPCR family 2 0.0033 0.0038 0.0037
Plasmodium vivax mitogen-activated protein kinase phosphatase 1, putative 0.0031 0.0032 0.1248
Echinococcus granulosus arachidonate 5 lipoxygenase 0.053 0.1394 0.1393
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0047 0.0075 0.0945
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0156 0.1972
Loa Loa (eye worm) hypothetical protein 0.0054 0.0096 0.0525
Trichomonas vaginalis cdc25a, putative 0.0031 0.0032 0.0111
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0005 0.00000000028147
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0096
Brugia malayi Cathepsin L-like precursor 0.0036 0.0047 0.0253
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0148 0.1873
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0931 0.2489 1
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0018 0.0018
Brugia malayi translation initiation factor 4E 0.0035 0.0044 0.0235
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.005 0.0085 0.0085
Loa Loa (eye worm) jmjC domain-containing protein 0.0129 0.0301 0.1649
Loa Loa (eye worm) succinate-ubiquinone oxidoreductase 0.0022 0.0007 0.0037
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0036 0.0047 0.0171
Mycobacterium tuberculosis Conserved protein 0.0031 0.0032 0.0028
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0051 0.0087 0.0087
Schistosoma mansoni nuclear receptor 0.0025 0.0018 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0427 0.1701
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.008 0.008
Brugia malayi succinate dehydrogenase [ubiquinone] iron-sulfur protein, mitochondrial 0.0051 0.0087 0.0472
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0118 0.027 0.027
Echinococcus granulosus succinate dehydrogenase ubiquinone iron sulfur 0.0051 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0054 0.0095 0.0523
Onchocerca volvulus 0.0076 0.0156 0.0728
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0062 0.0117 0.0307
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0077 0.0971
Brugia malayi AKH receptor 0.0051 0.0087 0.0473
Onchocerca volvulus 0.0051 0.0087 0.0398
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0403 0.1603
Mycobacterium ulcerans DNA polymerase IV 0.0108 0.0243 0.0637
Echinococcus granulosus peptide allatostatin:somatostatin 0.0051 0.0087 0.0086
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0047 0.0047
Trypanosoma brucei unspecified product 0.0094 0.0204 0.2582
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0047 0.0075 0.296
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0087 0.0086
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0018 0.0017
Toxoplasma gondii histone lysine methyltransferase SET1 0.0189 0.0463 0.975
Brugia malayi Cell death protein 3 precursor 0.0185 0.0453 0.2479
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0059 0.0109 0.1383
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0082 0.0312
Echinococcus multilocularis caspase 2 0.0185 0.0453 0.0453
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0049 0.0082 0.0312
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0062 0.0118 0.2461
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0065 0.0064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0047 0.0171
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0051 0.0087 0.0087
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0018 0.069
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0087 0.0086
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Mycobacterium tuberculosis Conserved protein 0.0023 0.0011 0.0005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0087 0.0086
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0193 0.0475 0.0474
Echinococcus granulosus L aminoadipate semialdehyde 0.0177 0.0432 0.0432
Onchocerca volvulus 0.0036 0.0047 0.0205
Brugia malayi jmjC domain containing protein 0.0054 0.0096 0.0521
Brugia malayi hypothetical protein 0.0025 0.0018 0.0092
Trypanosoma brucei protein kinase, putative 0.0111 0.0251 0.3181
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.0583
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0022 0.0008 0.0305
Schistosoma mansoni blooms syndrome DNA helicase 0.0058 0.0105 0.0105
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0022 0.0008 0.0078
Leishmania major hypothetical protein, conserved 0.0028 0.0025 0.0306
Onchocerca volvulus 0.0051 0.0087 0.0398
Brugia malayi hypothetical protein 0.0051 0.0087 0.0473
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0253 0.064 0.0639
Mycobacterium ulcerans fatty acid synthase Fas 0.0024 0.0014 0.0035
Echinococcus multilocularis expressed protein 0.0039 0.0053 0.0052
Echinococcus granulosus 5'partial|tRNA 2 selenouridine synthase 0.0031 0.0032 0.0031
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0048 0.026
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.0243 0.3079
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0031 0.0032 0.0399
Loa Loa (eye worm) fatty acid synthase 0.0076 0.0156 0.0852
Schistosoma mansoni jumonji domain containing protein 0.0291 0.0741 0.0741
Echinococcus multilocularis dna polymerase eta 0.005 0.0085 0.0085
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0126 0.0292 0.3711
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Trypanosoma brucei metacaspase 5, putative 0.0096 0.021 0.2659
Trypanosoma cruzi cysteine peptidase, putative 0.0036 0.0047 0.0587
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0022 0.0008 0.0097
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Echinococcus granulosus ecdysone induced protein 78C 0.0054 0.0095 0.0095
Mycobacterium tuberculosis Conserved protein 0.0076 0.0156 0.0165
Brugia malayi Inositol-1 0.0037 0.005 0.0271
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.005 0.063
Schistosoma mansoni hypothetical protein 0.0169 0.0409 0.0409
Loa Loa (eye worm) CXXC zinc finger family protein 0.0091 0.0198 0.1082
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0018 0.022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.0095 0.0519
Brugia malayi PHD-finger family protein 0.004 0.0057 0.0309
Schistosoma mansoni hypothetical protein 0.0169 0.0409 0.0409
Schistosoma mansoni neuropeptide f receptor 76f 0.0051 0.0087 0.0087
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0022 0.0008 0.002
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0048 0.0176
Trypanosoma cruzi metacaspase 5, putative 0.0096 0.021 0.2659
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0031 0.0032 0.0111
Mycobacterium ulcerans hypothetical protein 0.0076 0.0156 0.0408
Toxoplasma gondii NADPH-glutathione reductase 0.0022 0.0008 0.0161
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0029 0.0026 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0325 0.4127
Echinococcus granulosus jumonji domain containing protein 0.0087 0.0186 0.0185
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0108 0.0243 0.0959
Echinococcus granulosus tachykinin peptides receptor 99D 0.0051 0.0087 0.0086
Schistosoma mansoni rotamase 0.0039 0.0053 0.0053
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0129 0.03 0.3802
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0038 0.0037
Echinococcus multilocularis Protein lozenge 0.0064 0.0123 0.0122
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0115 0.0263 0.0283
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.021 0.0826
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0047 0.0171
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0051 0.0087 0.0473
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0931 0.2489 1
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0251 0.0991
Onchocerca volvulus 0.0051 0.0087 0.0398
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0096 0.021 0.0826
Schistosoma mansoni thyroid hormone receptor 0.0327 0.084 0.084
Onchocerca volvulus 0.0036 0.0047 0.0205
Brugia malayi Rhodanese-like domain containing protein 0.0031 0.0032 0.0172
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Onchocerca volvulus 0.0051 0.0087 0.0398
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0049 0.0082 0.0081
Entamoeba histolytica hypothetical protein 0.0031 0.0032 0.0072
Toxoplasma gondii peptidylprolyl isomerase 0.0038 0.0051 0.105
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0118 0.027 0.027
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0076 0.0156 0.1979
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0097 0.0212 0.0227
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0008 0.0097
Loa Loa (eye worm) hypothetical protein 0.0107 0.0241 0.1317
Mycobacterium tuberculosis Conserved hypothetical protein 0.0047 0.0075 0.0076
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0035 0.0044 0.0119
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0018 0.0017
Brugia malayi ecdysteroid receptor 0.0054 0.0095 0.0519
Schistosoma mansoni amine GPCR 0.0051 0.0087 0.0087
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0022 0.0008 0.0042
Trypanosoma brucei mercaptopyruvate sulfurtransferase, putative 0.0031 0.0032 0.0399
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0931 0.2489 1
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0038 0.0202
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.0013 0.0492
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0319 0.0818 0.0817
Schistosoma mansoni aldehyde dehydrogenase 0.0193 0.0475 0.0475
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0051 0.0087 0.0086
Leishmania major As/Sb Reductase 0.0031 0.0032 0.0399
Brugia malayi exodeoxyribonuclease III family protein 0.0059 0.0109 0.0595
Brugia malayi nuclear hormone receptor 0.0054 0.0095 0.0519
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0062 0.0118 0.2461
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0087 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0047 0.0171
Trypanosoma cruzi As/Sb Reductase, putative 0.0031 0.0032 0.0399
Schistosoma mansoni hypothetical protein 0.0021 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0477
Schistosoma mansoni neuropeptide receptor 0.0051 0.0087 0.0087
Echinococcus granulosus histone acetyltransferase KAT2B 0.0097 0.0212 0.0211
Leishmania major cathepsin L-like protease 0.0036 0.0047 0.0587
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0077 0.0158 0.0168
Leishmania major mitochondrial DNA polymerase beta 0.0307 0.0787 1
Brugia malayi hypothetical protein 0.0051 0.0087 0.0473
Plasmodium vivax vivapain-2 0.0036 0.0047 0.1839
Onchocerca volvulus 0.0051 0.0087 0.0398
Onchocerca volvulus 0.0036 0.0047 0.0205
Schistosoma mansoni cpg binding protein 0.0099 0.0217 0.0217
Trypanosoma brucei metacaspase MCA3 0.0096 0.021 0.2659
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0031 0.0032 0.0399
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0018 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0931 0.2489 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0059 0.0109 0.0385
Leishmania major cathepsin L-like protease 0.0036 0.0047 0.0587
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.039 0.0424
Toxoplasma gondii aldehyde dehydrogenase 0.0193 0.0475 1
Brugia malayi Cathepsin L-like precursor 0.0036 0.0047 0.0253
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0076 0.0156 0.1979
Mycobacterium ulcerans Type I modular polyketide synthase 0.0077 0.0158 0.0415
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.004 0.0086
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0087 0.0086
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.008 0.0366
Echinococcus multilocularis cysteine protease 0.0036 0.0047 0.0046
Trypanosoma brucei metacaspase 0.0096 0.021 0.2659
Echinococcus granulosus JmjC domain containing protein 4 0.0054 0.0096 0.0095
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0022 0.0008 0.0097
Mycobacterium ulcerans molybdopterin biosynthesis-like protein MoeZ 0.0031 0.0032 0.0082
Schistosoma mansoni hypothetical protein 0.0033 0.0038 0.0038
Echinococcus granulosus dro:myosuppressin receptor 0.0051 0.0087 0.0086
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0087 0.0086
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0099 0.0536
Echinococcus multilocularis CREB binding protein 0.0081 0.0168 0.0167

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 3.3 nM Inhibition of human thrombin ChEMBL. 19674897

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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