Detailed information for compound 107574

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 334.372 | Formula: C19H18N4O2
  • H donors: 1 H acceptors: 3 LogP: 3.81 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1cc2c(ncnc2cc1OCC)Nc1cccc(c1)C#N
  • InChi: 1S/C19H18N4O2/c1-3-24-17-9-15-16(10-18(17)25-4-2)21-12-22-19(15)23-14-7-5-6-13(8-14)11-20/h5-10,12H,3-4H2,1-2H3,(H,21,22,23)
  • InChiKey: DCEONHCODXDXDK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens fructose-1,6-bisphosphatase 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative Get druggable targets OG5_127400 All targets in OG5_127400
Echinococcus multilocularis fructose 1,6 bisphosphatase 1 Get druggable targets OG5_127400 All targets in OG5_127400
Trypanosoma brucei gambiense fructose-1,6-bisphosphate, cytosolic, putative Get druggable targets OG5_127400 All targets in OG5_127400
Candida albicans similar to S. cerevisiae FBP1 (YLR377C) Fructose-1,6-bisphosphatase Get druggable targets OG5_127400 All targets in OG5_127400
Toxoplasma gondii fructose-bisphospatase II Get druggable targets OG5_127400 All targets in OG5_127400
Leishmania mexicana fructose-1,6-bisphosphatase, cytosolic, putative Get druggable targets OG5_127400 All targets in OG5_127400
Leishmania major Get druggable targets OG5_127400 All targets in OG5_127400
Leishmania donovani fructose-1,6-bisphosphatase, cytosolic, putative Get druggable targets OG5_127400 All targets in OG5_127400
Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_127400 All targets in OG5_127400
Trypanosoma congolense fructose-1,6-bisphosphate, cytosolic, putative Get druggable targets OG5_127400 All targets in OG5_127400
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative Get druggable targets OG5_127400 All targets in OG5_127400
Leishmania infantum fructose-1,6-bisphosphatase, cytosolic, putative Get druggable targets OG5_127400 All targets in OG5_127400
Schistosoma mansoni fructose-16-bisphosphatase-related Get druggable targets OG5_127400 All targets in OG5_127400
Loa Loa (eye worm) fructose-1,6-bisphosphatase Get druggable targets OG5_127400 All targets in OG5_127400
Trypanosoma brucei fructose-1,6-bisphosphatase Get druggable targets OG5_127400 All targets in OG5_127400
Echinococcus granulosus fructose 16 bisphosphatase 1 Get druggable targets OG5_127400 All targets in OG5_127400
Leishmania braziliensis fructose-1,6-bisphosphatase, cytosolic, putative Get druggable targets OG5_127400 All targets in OG5_127400
Schistosoma japonicum ko:K03841 fructose-1,6-bisphosphatase I, putative Get druggable targets OG5_127400 All targets in OG5_127400
Neospora caninum Fructose-1 6-biphosphatase, related Get druggable targets OG5_127400 All targets in OG5_127400
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Toxoplasma gondii fructose-bisphospatase I fructose-1,6-bisphosphatase 1 338 aa 326 aa 31.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0041 0.0371 0.0371
Echinococcus granulosus cyclic AMP responsive element binding protein 0.0008 0.0004 0.0004
Mycobacterium leprae Probable polyketide synthase Pks1 0.0019 0.0127 0.0606
Echinococcus granulosus chromobox protein 1 0.0033 0.0278 0.0278
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0098 0.0994 0.5019
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0011 0.0042 0.0119
Entamoeba histolytica heat shock protein 90, putative 0.0046 0.0424 0.0721
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.002 0.0144 0.0729
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0027 0.0219 0.1105
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0019 0.0133 0.0377
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.007 0.0679 0.0679
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0187 0.1954 0.5534
Trypanosoma brucei heat shock protein, putative 0.0046 0.0424 0.2139
Echinococcus granulosus single minded 2 0.0023 0.0168 0.0168
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0034 0.0289 0.0819
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0616 0.0616
Brugia malayi latrophilin 2 splice variant baaae 0.0133 0.1372 0.3886
Echinococcus multilocularis hyperpolarization activated cyclic 0.001 0.003 0.003
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0009 0.0016 0.0057
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0025 0.0195 0.1082
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0017 0.0107 0.0384
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.006 0.0572 0.0572
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0032 0.0274 0.0775
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0056 0.0529 0.2672
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0008 0.0007 0.0017
Toxoplasma gondii Hsp90 domain-containing protein 0.0173 0.1802 0.9104
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Trypanosoma brucei PAB1-binding protein , putative 0.002 0.0136 0.0685
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.018 0.049
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0009 0.0021 0.0114
Brugia malayi hypothetical protein 0.0009 0.0021 0.0058
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0187 0.1954 0.1954
Echinococcus multilocularis cyclic AMP responsive element binding protein 0.0008 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0062 0.0593 0.0593
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0577 0.0577
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0027 0.0219 0.0783
Loa Loa (eye worm) hypothetical protein 0.0013 0.0066 0.018
Loa Loa (eye worm) hypothetical protein 0.0064 0.0616 0.1671
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0009 0.0018 0.0065
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0017 0.0107 0.0384
Onchocerca volvulus 0.0032 0.0274 0.0783
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0187 0.1954 0.1954
Entamoeba histolytica Ran family GTPase 0.0024 0.018 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0121 0.0206
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.007 0.0686 0.0686
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0032 0.0274 0.0274
Brugia malayi AMP-binding enzyme family protein 0.0017 0.0107 0.0302
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0014 0.0077 0.0277
Brugia malayi bZIP transcription factor family protein 0.0008 0.0004 0.001
Brugia malayi nuclear receptor RXR 0.0088 0.088 0.2492
Echinococcus multilocularis dna polymerase kappa 0.0026 0.0204 0.0204
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.001 0.003 0.0051
Plasmodium vivax SET domain protein, putative 0.0025 0.0194 0.1075
Schistosoma mansoni single-minded 0.0024 0.0186 0.0186
Trichomonas vaginalis endoplasmin, putative 0.0034 0.0287 0.0489
Onchocerca volvulus 0.011 0.112 0.3202
Loa Loa (eye worm) hypothetical protein 0.001 0.003 0.0082
Entamoeba histolytica protein tyrosine phosphatase, putative 0.011 0.112 0.1906
Loa Loa (eye worm) hypothetical protein 0.0009 0.0018 0.0049
Echinococcus multilocularis GA binding protein alpha chain 0.0032 0.0265 0.0265
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0043 0.0387 0.1385
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.011 0.112 0.4009
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0041 0.0371 0.1007
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0108 0.1102 0.1102
Brugia malayi Importin beta-1 subunit 0.0032 0.0273 0.0774
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0018 0.0115 0.0115
Trypanosoma brucei heat shock protein, putative 0.0046 0.0424 0.2139
Onchocerca volvulus 0.0009 0.0018 0.0052
Loa Loa (eye worm) acyl carrier protein 0.0008 0.001 0.0028
Brugia malayi SWIRM domain containing protein 0.0009 0.0021 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0187 0.1954 0.5534
Loa Loa (eye worm) hypothetical protein 0.0088 0.088 0.2389
Loa Loa (eye worm) hypothetical protein 0.0015 0.0085 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0063 0.0107
Loa Loa (eye worm) heat shock protein 75 0.003 0.0251 0.0681
Schistosoma mansoni hypothetical protein 0.0548 0.5886 0.5886
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0041 0.0371 0.1328
Mycobacterium ulcerans oxidoreductase 0.0009 0.0021 0.0074
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0624 0.0624
Brugia malayi nuclear hormone receptor 0.0088 0.088 0.2492
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0056 0.0529 0.1894
Trichomonas vaginalis heat shock protein, putative 0.0026 0.021 0.0357
Onchocerca volvulus Heterochromatin protein 1 homolog 0.002 0.0136 0.039
Schistosoma mansoni aldehyde dehydrogenase 0.0075 0.0739 0.0739
Trypanosoma cruzi heat shock protein 90, putative 0.0046 0.0424 0.2139
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0018 0.0121 0.0576
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0018 0.0121 0.0328
Loa Loa (eye worm) transcription factor SMAD2 0.008 0.0791 0.2146
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0027 0.0212 0.0212
Onchocerca volvulus 0.0061 0.0582 0.1666
Loa Loa (eye worm) hypothetical protein 0.0023 0.017 0.0461
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0424 0.2139
Schistosoma mansoni hypothetical protein 0.0026 0.0206 0.0206
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0009 0.0021 0.0021
Echinococcus granulosus inositol monophosphatase 1 0.002 0.0144 0.0144
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0027 0.0219 0.0783
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Loa Loa (eye worm) follicle stimulating hormone receptor 0.018 0.1885 0.5115
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0025 0.0195 0.0986
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0056 0.0529 0.2672
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.011 0.112 0.304
Loa Loa (eye worm) hypothetical protein 0.0041 0.0371 0.1007
Schistosoma mansoni camp-response element binding protein-related 0.0008 0.0004 0.0004
Echinococcus granulosus fetal alzheimer antigen falz 0.0012 0.0057 0.0057
Schistosoma mansoni cpg binding protein 0.0054 0.0514 0.0514
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0023 0.017 0.0942
Schistosoma mansoni intermediate filament proteins 0.0024 0.0178 0.0178
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.0189 0.198 1
Mycobacterium leprae Conserved hypothetical protein 0.0017 0.0107 0.0511
Schistosoma mansoni lamin 0.0024 0.0178 0.0178
Onchocerca volvulus 0.0041 0.0371 0.1061
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Trypanosoma brucei heat shock protein, putative 0.0046 0.0424 0.2139
Brugia malayi glutaminase DH11.1 0.0096 0.0966 0.2735
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0025 0.0195 0.3688
Schistosoma mansoni zinc finger protein 0.0013 0.0065 0.0065
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.007 0.0679 0.0679
Brugia malayi jmjC domain containing protein 0.006 0.0577 0.1633
Brugia malayi SET domain containing protein 0.0007 0.0001 0.0003
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0056 0.0529 0.252
Loa Loa (eye worm) hypothetical protein 0.0027 0.0215 0.0583
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.0079
Loa Loa (eye worm) nuclear hormone receptor 0.0088 0.088 0.2389
Brugia malayi Cation transporter family protein 0.007 0.0686 0.1942
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.007 0.0686 0.1942
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0008 0.0004 0.0004
Echinococcus granulosus histone acetyltransferase KAT2B 0.0025 0.019 0.019
Plasmodium vivax ataxin-2 like protein, putative 0.002 0.0136 0.0752
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0577 0.0577
Brugia malayi exodeoxyribonuclease III family protein 0.0025 0.0195 0.0552
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.007 0.0686 0.0686
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0009 0.0023 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.0079
Loa Loa (eye worm) hypothetical protein 0.0015 0.0085 0.0231
Trypanosoma brucei fructose-1,6-bisphosphatase 0.0189 0.198 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.003 0.0251 0.0251
Trypanosoma brucei DNA polymerase IV, putative 0.0024 0.0183 0.0926
Schistosoma mansoni hypothetical protein 0.0062 0.0593 0.0593
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.017 0.0858
Loa Loa (eye worm) endoplasmin 0.0046 0.0424 0.115
Brugia malayi hypothetical protein 0.0099 0.0995 0.2818
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.0593 0.0593
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0179 0.1872 0.6701
Toxoplasma gondii melibiase subfamily protein 0.0027 0.0212 0.1068
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0098 0.0994 0.5019
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0027 0.0219 0.1105
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0187 0.1954 0.1954
Trichomonas vaginalis ran, putative 0.0024 0.018 0.0307
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.02 0.21 0.7517
Onchocerca volvulus 0.007 0.0686 0.1961
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0027 0.0219 0.1213
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0065 0.0624 0.0624
Trichomonas vaginalis ap endonuclease, putative 0.0025 0.0195 0.0332
Plasmodium vivax endoplasmin, putative 0.0046 0.0424 0.235
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Brugia malayi hypothetical protein 0.0032 0.0274 0.0775
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0009 0.0017 0.0017
Brugia malayi Cyclic-nucleotide gated cation channel 0.001 0.003 0.0086
Plasmodium falciparum heat shock protein 90 0.0046 0.0424 0.235
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0025 0.0195 0.0552
Brugia malayi MAP kinase sur-1 0.0098 0.0994 0.2813
Trypanosoma brucei heat shock protein, putative 0.0046 0.0424 0.2139
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0273 0.0273
Schistosoma mansoni nAChR subunit 0.007 0.0686 0.0686
Leishmania major phosphopantetheinyl transferase-like protein 0.0017 0.0107 0.054
Brugia malayi Pre-SET motif family protein 0.0168 0.1751 0.4957
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0168 0.1751 0.4752
Brugia malayi nuclear hormone receptor 0.0187 0.1954 0.5534
Loa Loa (eye worm) hypothetical protein 0.0062 0.0593 0.1609
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0621 0.0621
Trypanosoma cruzi DNA polymerase kappa, putative 0.0026 0.0204 0.103
Schistosoma mansoni glutaminase 0.0096 0.0966 0.0966
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0081 0.0081
Loa Loa (eye worm) intermediate filament protein 0.0024 0.0178 0.0483
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0025 0.0195 0.1082
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0068 0.0068
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0027 0.0219 0.1105
Giardia lamblia Kinase, CMGC MAPK 0.0098 0.0994 0.2538
Giardia lamblia Heat shock protein HSP 90-alpha 0.0039 0.0346 0.0883
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0027 0.0219 0.0219
Brugia malayi cytochrome P450 0.0017 0.0107 0.0304
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0136 0.0685
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0068 0.0659 0.0659
Echinococcus granulosus Nuclear hormone receptor HR96 0.0088 0.088 0.088
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0017 0.0107 0.0384
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0017 0.0107 0.0273
Echinococcus multilocularis glycine receptor subunit beta 0.0108 0.1103 0.1103
Schistosoma mansoni carbonic anhydrase-related 0.0025 0.0195 0.0195
Schistosoma mansoni ets-related 0.0096 0.0964 0.0964
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0027 0.0219 0.1213
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0367 0.3915 0.6664
Trichomonas vaginalis heat shock protein, putative 0.0046 0.0424 0.0721
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0027 0.0211 0.0757
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0081 0.0808 0.0808
Schistosoma mansoni chromobox protein 0.0033 0.0278 0.0278
Leishmania major cathepsin L-like protease 0.0023 0.017 0.0858
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.001 0.001
Mycobacterium ulcerans lipase LipD 0.0009 0.0018 0.0065
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.018 0.0461
Schistosoma mansoni gabp alpha 0.0032 0.0265 0.0265
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0187 0.1954 0.5304
Echinococcus multilocularis isocitrate dehydrogenase 0.001 0.003 0.003
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0187 0.1954 0.5304
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0009 0.0021 0.0074
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0009 0.0021 0.0098
Leishmania major hypothetical protein, conserved 0.002 0.0136 0.0685
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0009 0.0016 0.0057
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0027 0.0212 0.0212
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.018 0.0911
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0017 0.0107 0.0384
Onchocerca volvulus 0.0032 0.0274 0.0783
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0017 0.0105 0.0298
Onchocerca volvulus 0.0024 0.0178 0.0509
Schistosoma mansoni hypothetical protein 0.0009 0.0017 0.0017
Trichomonas vaginalis chromobox protein, putative 0.002 0.0136 0.0232
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0017 0.0107 0.0384
Echinococcus multilocularis transcription factor Dp 1 0.0035 0.0298 0.0298
Leishmania major importin beta-1 subunit, putative 0.0026 0.0207 0.1045
Trypanosoma brucei protein kinase, putative 0.0098 0.0994 0.5019
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0023 0.017 0.017
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0038 0.0333 0.0333
Leishmania major cathepsin L-like protease 0.0023 0.017 0.0858
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0038 0.0333 0.0943
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.007 0.0686 0.1942
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0026 0.0204 0.0347
Brugia malayi Carboxylesterase family protein 0.0041 0.0371 0.1051
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0241 0.255 0.255
Trypanosoma brucei heat shock protein, putative 0.0046 0.0424 0.2139
Brugia malayi jmjC domain containing protein 0.0015 0.0085 0.0241
Brugia malayi hypothetical protein 0.0082 0.081 0.2294
Echinococcus granulosus leucine aminopeptidase protein 0.0056 0.0529 0.0529
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0577 0.1566
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Brugia malayi F/Y-rich N-terminus family protein 0.0017 0.0108 0.0306
Trypanosoma brucei heat shock protein, putative 0.0046 0.0424 0.2139
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.007 0.0679 0.0679
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0252 0.0252
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0195 0.2044 0.5548
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0994 0.1691
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.018 0.0911
Brugia malayi Melibiase family protein 0.0018 0.0115 0.0325
Brugia malayi RNA binding protein 0.0064 0.0621 0.1759
Leishmania major heat shock protein, putative 0.003 0.0251 0.1267
Trypanosoma brucei unspecified product 0.0024 0.0183 0.0926
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0276 0.2932 0.2932
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0088 0.088 0.088
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.007 0.0686 0.0686
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Onchocerca volvulus 0.0031 0.0263 0.0753
Trypanosoma cruzi UDP-galactopyranose mutase 0.0009 0.0021 0.0104
Mycobacterium ulcerans hypothetical protein 0.0009 0.0018 0.0065
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0025 0.0195 0.0332
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0027 0.0219 0.1105
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0549 0.1489
Leishmania major DNA polymerase kappa, putative 0.002 0.0141 0.0714
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.001 0.003 0.0154
Toxoplasma gondii thioredoxin reductase 0.0079 0.078 0.3941
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0017 0.0107 0.0384
Schistosoma mansoni hypothetical protein 0.0008 0.0004 0.0004
Mycobacterium ulcerans glutaminase 0.0096 0.0966 0.3458
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0085 0.0085
Brugia malayi cytosol aminopeptidase 0.0011 0.0042 0.0119
Brugia malayi isocitrate dehydrogenase 0.001 0.003 0.0086
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Brugia malayi Ets-domain containing protein 0.0032 0.0265 0.0749
Mycobacterium tuberculosis Probable thioesterase TesA 0.0015 0.0083 0.0297
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0041 0.0371 0.0371
Brugia malayi Fli-1 protein 0.0096 0.0964 0.2731
Echinococcus multilocularis 0.0009 0.0021 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0187 0.1954 0.5534
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0017 0.0107 0.0384
Loa Loa (eye worm) hypothetical protein 0.0317 0.3373 0.9156
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0056 0.0529 0.2672
Trypanosoma cruzi cysteine peptidase, putative 0.0023 0.017 0.0858
Onchocerca volvulus 0.0107 0.1082 0.3093
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0018 0.0091
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0018 0.0091
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0387 0.0659
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0187 0.1954 0.5534
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0017 0.0107 0.0542
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0291 0.1468
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0027 0.0219 0.4134
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0187 0.1954 0.1954
Schistosoma mansoni zinc finger protein 0.0088 0.088 0.088
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0021 0.0148 0.0749
Mycobacterium ulcerans thioesterase 0.0015 0.0083 0.0297
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0187 0.1954 0.5304
Echinococcus granulosus cGMP dependent protein kinase 1 0.0008 0.0004 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0219 0.1105
Echinococcus multilocularis peptidase Clp (S14 family) 0.0015 0.0084 0.0084
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.018 0.1881 0.8958
Loa Loa (eye worm) hypothetical protein 0.0038 0.0333 0.0904
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0099 0.0995 0.0995
Loa Loa (eye worm) hypothetical protein 0.0009 0.0018 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.017 0.0858
Onchocerca volvulus Fatty acid synthase homolog 0.0032 0.0271 0.0776
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0624 0.1768
Loa Loa (eye worm) hypothetical protein 0.0015 0.0081 0.022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0037 0.0064
Trichomonas vaginalis D-aminoacylase, putative 0.0009 0.0018 0.0031
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Trypanosoma brucei aminopeptidase, putative 0.0011 0.0042 0.0213
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0204 0.103
Trypanosoma cruzi cysteine peptidase, putative 0.0023 0.017 0.0858
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0187 0.1954 0.5589
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.007 0.0686 0.1942
Schistosoma mansoni BC026374 protein (S09 family) 0.0041 0.0371 0.0371
Trypanosoma brucei unspecified product 0.0013 0.0059 0.0296
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0191 0.2004 0.2004
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.001 0.003 0.003
Schistosoma mansoni heat shock protein 0.003 0.0251 0.0251
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.0577 0.0577
Mycobacterium tuberculosis Conserved protein 0.0009 0.0018 0.0065
Echinococcus multilocularis dnaJ subfamily B 0.0562 0.6048 0.6048
Echinococcus multilocularis voltage gated potassium channel 0.0015 0.0081 0.0081
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0616 0.0616
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0012 0.0054 0.0274
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0017 0.0107 0.0542
Trichomonas vaginalis DNA polymerase eta, putative 0.0026 0.0204 0.0347
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0062 0.0593 0.0593
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0012 0.0049 0.0177
Trichomonas vaginalis receptor histidine kinase, putative 0.0009 0.0023 0.0039
Echinococcus granulosus glycine receptor subunit beta 0.0108 0.1103 0.1103
Loa Loa (eye worm) hypothetical protein 0.0025 0.0195 0.0529
Loa Loa (eye worm) hypothetical protein 0.0088 0.088 0.2389
Leishmania major cytochrome p450-like protein 0.0017 0.0107 0.0542
Schistosoma mansoni hypothetical protein 0.0009 0.0017 0.0017
Loa Loa (eye worm) glutathione reductase 0.0079 0.078 0.2118
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0098 0.0994 0.5019
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Trypanosoma cruzi DNA polymerase kappa, putative 0.0026 0.0204 0.103
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.002 0.014 0.0396
Entamoeba histolytica hypothetical protein 0.0122 0.1252 0.2131
Loa Loa (eye worm) fructose-1,6-bisphosphatase 0.0189 0.198 0.5373
Onchocerca volvulus 0.0024 0.0178 0.0509
Schistosoma mansoni nuclear hormone receptor 0.0088 0.088 0.088
Loa Loa (eye worm) hypothetical protein 0.0009 0.0021 0.0056
Trypanosoma brucei carbonic anhydrase-like protein 0.0068 0.0659 0.3329
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0027 0.0219 0.1105
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0621 0.1759
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0017 0.0107 0.0384
Toxoplasma gondii aldehyde dehydrogenase 0.0075 0.0739 0.3734
Loa Loa (eye worm) hypothetical protein 0.0041 0.0371 0.1007
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0018 0.0115 0.0413
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.007 0.0686 0.1861
Loa Loa (eye worm) ACC-1 protein 0.007 0.0686 0.1861
Trichomonas vaginalis D-aminoacylase, putative 0.0009 0.0018 0.0031
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.001 0.003 0.003
Onchocerca volvulus 0.0018 0.0117 0.0335
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.017 0.0858
Loa Loa (eye worm) hypothetical protein 0.0099 0.0995 0.2701
Giardia lamblia Histone acetyltransferase GCN5 0.0022 0.0157 0.0401
Echinococcus granulosus lysine specific histone demethylase 1A 0.0009 0.0021 0.0021
Toxoplasma gondii heat shock protein 90, putative 0.0046 0.0424 0.2139
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0498 0.2515
Onchocerca volvulus 0.0038 0.0333 0.0952
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.017 0.0858
Brugia malayi bZIP transcription factor family protein 0.0008 0.0004 0.001
Brugia malayi Protein-tyrosine phosphatase containing protein 0.007 0.0679 0.1922
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0025 0.0195 0.0195
Brugia malayi Carboxylesterase family protein 0.0041 0.0371 0.1051
Onchocerca volvulus 0.0041 0.0371 0.1061
Brugia malayi hypothetical protein 0.0064 0.0616 0.1743
Mycobacterium ulcerans carboxylesterase, LipT 0.0264 0.2793 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0624 0.2236
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0009 0.0016 0.0057
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0009 0.0021 0.0021
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0076 0.075 0.2686
Loa Loa (eye worm) nuclear receptor NHR-67 0.0088 0.088 0.2389
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.007 0.0686 0.1942
Echinococcus multilocularis musashi 0.0024 0.0178 0.0178
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0122 0.1252 0.1252
Brugia malayi Doublecortin family protein 0.0064 0.0616 0.1743
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0027 0.0219 0.1105
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0009 0.0016 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0187 0.1954 0.5534
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0187 0.1954 0.1954
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0219 0.1105
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0009 0.0016 0.0057
Brugia malayi Nuclear hormone receptor-like 1 0.0099 0.0995 0.2818
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.0079
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0019 0.0127 0.0456
Brugia malayi Bromodomain containing protein 0.0037 0.0322 0.0912
Onchocerca volvulus 0.007 0.0686 0.1961
Schistosoma mansoni lipoxygenase 0.0235 0.2485 0.2485
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0105 0.0178
Echinococcus multilocularis carboxylesterase 5A 0.0104 0.1052 0.1052
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0009 0.0018 0.0018
Echinococcus granulosus heat shock protein 90 0.0039 0.0346 0.0346
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0141 0.0506
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.02 0.21 0.7517
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.006 0.0572 0.0572
Brugia malayi Cation transporter family protein 0.0108 0.1103 0.3123
Loa Loa (eye worm) hypothetical protein 0.0064 0.0616 0.1671
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0027 0.0219 0.1105
Schistosoma mansoni hypothetical protein 0.0345 0.3684 0.3684
Echinococcus granulosus intermediate filament protein 0.0024 0.0178 0.0178
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0027 0.0211 0.0757
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0017 0.0107 0.0384
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Brugia malayi orphan nuclear receptor NR2E1 0.0088 0.088 0.2492
Mycobacterium tuberculosis Conserved hypothetical protein 0.0009 0.0021 0.0074
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0038 0.0333 0.0943
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0278 0.0473
Echinococcus granulosus neuroligin 0.0041 0.0371 0.0371
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.002 0.0144 0.0516
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0009 0.0018 0.0049
Schistosoma mansoni jumonji domain containing protein 0.0057 0.0537 0.0537
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.02 0.21 1
Echinococcus multilocularis carbonic anhydrase 0.0025 0.0195 0.0195
Loa Loa (eye worm) hypoxia-induced factor 1 0.0075 0.0741 0.2012
Echinococcus granulosus lysine specific histone demethylase 1A 0.0009 0.0021 0.0021
Brugia malayi beta-lactamase 0.0009 0.0018 0.0051
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0017 0.0107 0.2022
Leishmania major trypanothione reductase 0.0079 0.078 0.3941
Echinococcus granulosus mitogen activated protein kinase 0.0098 0.0994 0.0994
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0017 0.0109 0.0391
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0075 0.0739 0.0739
Onchocerca volvulus 0.0187 0.1954 0.5589
Loa Loa (eye worm) CXXC zinc finger family protein 0.0051 0.0473 0.1285
Echinococcus granulosus para nitrobenzyl esterase 0.0041 0.0371 0.0371
Toxoplasma gondii isocitrate dehydrogenase 0.001 0.003 0.0154
Loa Loa (eye worm) hypothetical protein 0.0321 0.3413 0.9262
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0204 0.103
Echinococcus multilocularis thioredoxin glutathione reductase 0.008 0.0788 0.0788
Plasmodium vivax heat shock protein 90, putative 0.003 0.0251 0.1391
Echinococcus multilocularis inositol monophosphatase 1 0.002 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0187 0.1954 0.5304
Echinococcus granulosus snurportin 1 0.0345 0.3684 0.3684
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0018 0.0121 0.0346
Trichomonas vaginalis myo inositol monophosphatase, putative 0.002 0.0144 0.0246
Brugia malayi hypothetical protein 0.0122 0.1252 0.3544
Schistosoma mansoni carbonic anhydrase-related 0.0025 0.0195 0.0195
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.007 0.0686 0.0686
Loa Loa (eye worm) hypothetical protein 0.0107 0.1082 0.2936
Toxoplasma gondii LsmAD domain-containing protein 0.002 0.0136 0.0685
Onchocerca volvulus 0.0041 0.0371 0.1061
Brugia malayi Steroid receptor seven-up type 2 0.0187 0.1954 0.5534
Plasmodium falciparum thioredoxin reductase 0.0079 0.078 0.4329
Plasmodium falciparum thioredoxin reductase 0.0027 0.0219 0.1213
Trichomonas vaginalis helicase, putative 0.0011 0.0046 0.0079
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0099 0.0995 0.0995
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0085 0.0085
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0018 0.0115 0.0326
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0013 0.0059 0.0159
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0009 0.0016 0.0057
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.007 0.0686 0.0686
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.018 0.0911
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0015 0.0084 0.04
Leishmania major cytochrome p450-like protein 0.0017 0.0107 0.0542
Schistosoma mansoni acetylcholinesterase 0.0041 0.0371 0.0371
Mycobacterium tuberculosis Probable hydrolase 0.0009 0.0018 0.0065
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0023 0.017 0.0608
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0068 0.0659 0.0659
Brugia malayi beta-lactamase family protein 0.0009 0.0018 0.0051
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0019 0.0127 0.0456
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0017 0.0107 0.0384
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.011 0.112 0.3171
Brugia malayi Latrophilin receptor protein 2 0.0062 0.0593 0.1678
Trichomonas vaginalis mercuric reductase, putative 0.0027 0.0219 0.0372
Echinococcus granulosus voltage gated potassium channel 0.0015 0.0081 0.0081
Echinococcus granulosus importin subunit beta 1 0.0032 0.0273 0.0273
Brugia malayi excitatory GABA receptor EXP-1A 0.007 0.0686 0.1942
Schistosoma mansoni inositol monophosphatase 0.002 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0008 0.0004 0.001
Echinococcus multilocularis hyperpolarization activated cyclic 0.001 0.003 0.003
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0009 0.0017 0.0017
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0017 0.0107 0.0594
Brugia malayi polk-prov protein 0.0013 0.0066 0.0188
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0008 0.0004 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0367 0.3915 0.6664
Echinococcus multilocularis leucyl aminopeptidase 0.0011 0.0042 0.0042
Echinococcus multilocularis carbonic anhydrase 0.0025 0.0195 0.0195
Brugia malayi Carboxylesterase family protein 0.0104 0.1052 0.2979
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0025 0.0195 0.0699
Toxoplasma gondii fructose-bisphospatase II 0.0189 0.198 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0235 0.2485 0.2485
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0011 0.0045 0.0045
Leishmania major cytochrome p450-like protein 0.0053 0.0498 0.2515
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0027 0.0212 0.0212
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0019 0.0127 0.0456
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0621 0.0621
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.003 0.0251 0.0251
Toxoplasma gondii exonuclease III APE 0.0025 0.0195 0.0986
Loa Loa (eye worm) carbonic anhydrase 3 0.0068 0.0659 0.1789
Echinococcus granulosus heat shock protein 90 0.0046 0.0424 0.0424
Loa Loa (eye worm) ACC-1 protein 0.007 0.0686 0.1861
Schistosoma mansoni ap endonuclease 0.0025 0.0195 0.0195
Onchocerca volvulus 0.0032 0.0274 0.0783
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0088 0.088 0.088
Echinococcus granulosus phd:f box containing protein 0.0015 0.0085 0.0085
Onchocerca volvulus 0.0051 0.0473 0.1354
Echinococcus granulosus acetylcholinesterase 0.0104 0.1052 0.1052
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.011 0.112 0.1906
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.011 0.112 0.1906
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0034 0.0291 0.0495
Echinococcus multilocularis Polycystic kidney disease protein 0.0064 0.0616 0.0616
Loa Loa (eye worm) hypothetical protein 0.0088 0.088 0.2389
Trypanosoma cruzi trypanothione reductase, putative 0.0027 0.0219 0.1105
Trypanosoma brucei heat shock protein 84, putative 0.003 0.0251 0.1267
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0101 0.0101
Mycobacterium tuberculosis Probable reductase 0.018 0.1881 0.6734
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0187 0.1954 0.1954
Brugia malayi nuclear receptor NHR-67 0.0088 0.088 0.2492
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0017 0.0107 0.0384
Brugia malayi photoreceptor-specific nuclear receptor 0.0187 0.1954 0.5534
Leishmania major hypothetical protein, conserved 0.0034 0.0291 0.1468
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0187 0.1954 0.1954
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0616 0.0616
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0187 0.1954 0.1954
Echinococcus granulosus glycine receptor subunit alpha 1 0.0108 0.1103 0.1103
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0098 0.0994 0.5019
Schistosoma mansoni neurotransmitter gated ion channel 0.0038 0.0333 0.0333
Entamoeba histolytica hypothetical protein 0.0017 0.0107 0.0182
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0187 0.1954 0.5304
Brugia malayi hypothetical protein 0.0032 0.0274 0.0775
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.006 0.0572 0.2891
Loa Loa (eye worm) hypothetical protein 0.0082 0.081 0.2199
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0009 0.0023 0.0432
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.017 0.0858
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0012 0.0047 0.0237
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0043 0.0387 0.7313
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0011 0.0042 0.0114
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0009 0.0021 0.0114
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0088 0.088 0.2389
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0041 0.0371 0.1328
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0367 0.3915 0.6664
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0009 0.0016 0.0057
Onchocerca volvulus 0.0009 0.0021 0.0059
Toxoplasma gondii histone lysine-specific demethylase 0.0009 0.0021 0.0104
Echinococcus granulosus cyclic nucleotide gated cation channel 0.001 0.003 0.003
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0331 0.3532 1
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0013 0.0061 0.0217
Brugia malayi Ets-domain containing protein 0.0032 0.0265 0.0749
Plasmodium falciparum heat shock protein 90, putative 0.0173 0.1802 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0057 0.0537 0.0537
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0017 0.0107 0.054
Trichomonas vaginalis set domain proteins, putative 0.0191 0.2002 0.3408
Schistosoma mansoni lamin 0.0024 0.0178 0.0178
Onchocerca volvulus 0.0041 0.0371 0.1061
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.006 0.0572 0.1553
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0219 0.1105
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.038 0.4065 0.4065
Chlamydia trachomatis protoporphyrinogen oxidase 0.0009 0.0021 0.0388
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.0081 0.0081
Toxoplasma gondii histone lysine methyltransferase SET1 0.01 0.101 0.5099
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.001 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0178 0.0483
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Echinococcus multilocularis endoplasmin 0.0043 0.0387 0.0387
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0101 0.0101
Loa Loa (eye worm) CYP4Cod1 0.0053 0.0498 0.1351
Loa Loa (eye worm) hypothetical protein 0.0328 0.3497 0.9491
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0009 0.0023 0.0118
Echinococcus granulosus mixed lineage leukemia protein mll 0.0013 0.0068 0.0068
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0105 0.0178
Brugia malayi jmjC domain containing protein 0.0015 0.0085 0.0241
Mycobacterium ulcerans Type I modular polyketide synthase 0.0018 0.0115 0.0413
Brugia malayi nuclear hormone receptor family member nhr-6 0.0088 0.088 0.2492
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0009 0.0016 0.0057
Mycobacterium ulcerans polyketide synthase 0.0019 0.0127 0.0456
Mycobacterium tuberculosis Possible oxidoreductase 0.0202 0.2123 0.7602
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0018 0.0115 0.0115
Echinococcus multilocularis microtubule associated protein 2 0.0925 1 1
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0009 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0187 0.1954 0.1954
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0025 0.0195 0.0552
Leishmania major carbonic anhydrase-like protein 0.0068 0.0659 0.3329
Schistosoma mansoni endoplasmin 0.0046 0.0424 0.0424
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0032 0.0265 0.0718
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.017 0.0858
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0017 0.0107 0.0384
Loa Loa (eye worm) hypothetical protein 0.0088 0.088 0.2389
Onchocerca volvulus 0.0088 0.088 0.2517
Mycobacterium tuberculosis Conserved protein 0.0009 0.0018 0.0065
Echinococcus granulosus cAMP responsive element binding protein 3 0.0008 0.0004 0.0004
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0085 0.0085
Plasmodium falciparum histone acetyltransferase GCN5 0.0022 0.0157 0.0872
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0187 0.1954 0.5534
Brugia malayi chromobox protein homolog 3 0.0018 0.0121 0.0343
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0063 0.0107
Mycobacterium leprae Probable lipase LipE 0.0009 0.0018 0.0086
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.007 0.0686 0.0686
Mycobacterium ulcerans thioesterase TesA 0.0015 0.0083 0.0297
Echinococcus multilocularis cyclic AMP dependent transcription factor ATF 6 0.0008 0.0004 0.0004
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0025 0.0195 0.0699
Plasmodium vivax multidomain scavenger receptor, putative 0.0064 0.0616 0.3415
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0018 0.0115 0.0549
Trypanosoma brucei isocitrate dehydrogenase, putative 0.001 0.003 0.0154
Onchocerca volvulus 0.0089 0.089 0.2544
Loa Loa (eye worm) hypothetical protein 0.0088 0.088 0.2389
Trichomonas vaginalis chromobox protein, putative 0.002 0.0136 0.0232
Loa Loa (eye worm) hypothetical protein 0.0269 0.285 0.7734
Echinococcus granulosus FTZ F1 alpha 0.0187 0.1954 0.1954
Brugia malayi Cytochrome P450 family protein 0.0017 0.0107 0.0304
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0424 0.2139
Brugia malayi jmjC domain containing protein 0.0015 0.0085 0.0241
Echinococcus multilocularis beta LACTamase domain containing family member 0.0009 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0015 0.0085 0.0231
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.011 0.112 0.2861
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0273 0.0273
Schistosoma mansoni camp-response element binding protein-related 0.0008 0.0004 0.0004
Leishmania major protein kinase, putative 0.0008 0.0004 0.0018
Loa Loa (eye worm) hypothetical protein 0.0088 0.088 0.2389
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.007 0.0686 0.1942
Echinococcus multilocularis nuclear receptor nhr 48 0.0088 0.088 0.088
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Loa Loa (eye worm) DR-78 0.0088 0.088 0.2389
Mycobacterium ulcerans leucyl aminopeptidase 0.0056 0.0529 0.1894
Schistosoma mansoni nuclear receptor nhr-48 0.0088 0.088 0.088
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0085 0.0231
Loa Loa (eye worm) hypothetical protein 0.0099 0.0995 0.2701
Echinococcus granulosus leucyl aminopeptidase 0.0011 0.0042 0.0042
Loa Loa (eye worm) thioredoxin reductase 0.0079 0.078 0.2118
Loa Loa (eye worm) hypothetical protein 0.0104 0.1052 0.2856
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0081 0.0081
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.001 0.003 0.003
Schistosoma mansoni survival motor neuron protein 0.0017 0.0105 0.0105
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Loa Loa (eye worm) GABA receptor subunit 0.0076 0.075 0.2036
Trypanosoma brucei Heat shock protein 83, putative 0.0046 0.0424 0.2139
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0219 0.1105
Schistosoma mansoni hypothetical protein 0.0017 0.0105 0.0105
Schistosoma mansoni hypothetical protein 0.0191 0.2004 0.2004
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.0593 0.1678
Echinococcus granulosus heat shock protein 0.0046 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0038 0.0333 0.0904
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Loa Loa (eye worm) hypothetical protein 0.0187 0.1954 0.5304
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0027 0.0219 0.1105
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0009 0.0017 0.0061
Onchocerca volvulus 0.0088 0.088 0.2517
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.007 0.0679 0.0679
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0071 0.0691 0.1875
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0346 0.1746
Schistosoma mansoni inositol monophosphatase 0.002 0.0144 0.0144
Loa Loa (eye worm) protein-tyrosine phosphatase 0.007 0.0679 0.1842
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0015 0.0084 0.0301
Trypanosoma brucei trypanothione reductase 0.0079 0.078 0.3941
Onchocerca volvulus 0.0014 0.0078 0.0223
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0088 0.088 0.088
Schistosoma mansoni neurotransmitter gated ion channel 0.0032 0.0274 0.0274
Loa Loa (eye worm) cytochrome P450 0.0017 0.0107 0.0291
Loa Loa (eye worm) hypothetical protein 0.0088 0.088 0.2389
Trypanosoma brucei hypothetical protein, conserved 0.0056 0.0533 0.2691
Brugia malayi Nuclear hormone receptor-like 1 0.0187 0.1954 0.5534
Schistosoma mansoni nAChR subunit 0.007 0.0686 0.0686
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0043 0.0387 0.1954
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0027 0.0219 0.1213
Echinococcus granulosus thioredoxin glutathione reductase 0.008 0.0788 0.0788
Echinococcus granulosus lamin dm0 0.0024 0.0178 0.0178
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.007 0.0686 0.0686
Loa Loa (eye worm) bZIP transcription factor family protein 0.0008 0.0004 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.0079
Echinococcus granulosus Nuclear hormone receptor HR96 0.0088 0.088 0.088
Echinococcus granulosus cyclic AMP dependent transcription factor ATF 6 0.0008 0.0004 0.0004
Loa Loa (eye worm) steroid hormone receptor 0.0187 0.1954 0.5304
Echinococcus granulosus carbonic anhydrase 0.0025 0.0195 0.0195
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0025 0.019 0.0958
Schistosoma mansoni aryl hydrocarbon receptor 0.0024 0.0186 0.0186
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0017 0.0107 0.0384
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.001 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0088 0.088 0.2389
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0011 0.0042 0.0213
Brugia malayi Probable ClpP-like protease 0.0023 0.017 0.0481
Loa Loa (eye worm) carboxylesterase 0.0041 0.0371 0.1007
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0345 0.3684 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0187 0.1954 0.1954
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0025 0.0194 0.0979
Echinococcus granulosus survival motor neuron protein 1 0.0083 0.0825 0.0825
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0624 0.0624
Echinococcus multilocularis cAMP responsive element binding protein 3 0.0008 0.0004 0.0004
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0125 0.0125
Echinococcus multilocularis chromobox protein 1 0.0033 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0025 0.0195 0.0529
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0023 0.017 0.0434
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0025 0.0195 0.0552
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0014 0.0077 0.0368
Brugia malayi Intermediate filament tail domain containing protein 0.0024 0.0178 0.0504
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0015 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0025 0.0195 0.0529
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0105 0.0178
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0187 0.1954 0.5534
Loa Loa (eye worm) hypothetical protein 0.0038 0.0333 0.0904
Loa Loa (eye worm) hypothetical protein 0.0009 0.0021 0.0056
Schistosoma mansoni lipoxygenase 0.0121 0.1235 0.1235
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0088 0.088 0.2517
Trypanosoma cruzi UDP-galactopyranose mutase 0.0009 0.0021 0.0104
Echinococcus multilocularis leucine aminopeptidase protein 0.0056 0.0529 0.0529
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0019 0.0133 0.0133
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0009 0.0023 0.0039
Onchocerca volvulus 0.0041 0.0371 0.1061
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0108 0.1103 0.1103
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0017 0.0107 0.0384
Brugia malayi Egg laying defective protein 4 0.0008 0.0004 0.001
Mycobacterium ulcerans monoamine oxidase 0.0009 0.0021 0.0074
Mycobacterium ulcerans Type I modular polyketide synthase 0.0018 0.0115 0.0413
Brugia malayi Cation transporter family protein 0.007 0.0686 0.1942
Brugia malayi Hsp90 protein 0.003 0.0251 0.071
Schistosoma mansoni nuclear receptor 0.0088 0.088 0.088
Onchocerca volvulus 0.0038 0.0333 0.0952
Brugia malayi Nuclear hormone receptor E75 0.0088 0.088 0.2492
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.017 0.0858
Loa Loa (eye worm) histone methyltransferase 0.0017 0.0101 0.0275
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.007 0.0686 0.1861
Brugia malayi hypothetical protein 0.0089 0.089 0.2519
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0085 0.0231
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0013 0.0068 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0204 0.103
Echinococcus multilocularis expressed conserved protein 0.0008 0.0004 0.0004
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0011 0.0042 0.0042
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0051 0.0473 0.0473
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0008 0.0004 0.0004
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.007 0.0686 0.0686
Loa Loa (eye worm) hypothetical protein 0.0032 0.0273 0.0741
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0023 0.017 0.0942
Loa Loa (eye worm) hypothetical protein 0.0187 0.1954 0.5304
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0081 0.0808 0.0808
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.018 0.1001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0187 0.1954 0.5534
Echinococcus granulosus hyperpolarization activated cyclic 0.001 0.003 0.003
Loa Loa (eye worm) fli-1 protein 0.0096 0.0964 0.2618
Schistosoma mansoni nuclear receptor 0.0088 0.088 0.088
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0034 0.0291 0.0495
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0002 0.0004
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.011 0.112 0.1906
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.018 0.1881 0.6734
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0187 0.1954 0.1954
Loa Loa (eye worm) glutaminase 0.0096 0.0966 0.2622
Mycobacterium ulcerans Type I modular polyketide synthase 0.0018 0.0115 0.0413
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0079 0.0401
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0098 0.0994 0.2697
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0068 0.0659 0.1866
Plasmodium falciparum glutathione reductase 0.0079 0.078 0.4329
Echinococcus granulosus dna polymerase kappa 0.0026 0.0204 0.0204
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.007 0.0686 0.0686
Loa Loa (eye worm) hypothetical protein 0.0023 0.0173 0.047
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.007 0.0686 0.1942
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Loa Loa (eye worm) AGC/PKG protein kinase 0.0008 0.0004 0.001
Echinococcus multilocularis chromobox protein 1 0.0033 0.0278 0.0278
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0219 0.1105
Schistosoma mansoni rab6-interacting 0.0064 0.0616 0.0616
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0108 0.1103 0.1103
Brugia malayi bHLH-PAS transcription factor 0.0018 0.0117 0.0332
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0621 0.0621
Echinococcus granulosus nAChR subunit 0.0038 0.0333 0.0333
Brugia malayi hypothetical protein 0.0328 0.3497 0.9902
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.007 0.0686 0.1942
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0187 0.1954 0.5534
Loa Loa (eye worm) acetylcholinesterase 1 0.0104 0.1052 0.2856
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0367 0.3915 0.6664
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0108 0.1103 0.2993
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0023 0.017 0.0608
Giardia lamblia NADH oxidase lateral transfer candidate 0.0027 0.0219 0.0559
Echinococcus multilocularis para nitrobenzyl esterase 0.0041 0.0371 0.0371
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0019 0.0133 0.0133
Echinococcus multilocularis FTZ F1 alpha 0.0187 0.1954 0.1954
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.001 0.003 0.003
Schistosoma mansoni ran 0.0024 0.018 0.018
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0143 0.1476 0.1476
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0017 0.0107 0.0384
Echinococcus granulosus expressed protein 0.0008 0.0004 0.0004
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.007 0.0686 0.0686
Echinococcus granulosus carbonic anhydrase 0.0025 0.0195 0.0195
Brugia malayi hypothetical protein 0.0032 0.0274 0.0775
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0274 0.0775
Echinococcus multilocularis thyroid hormone receptor alpha 0.0378 0.4038 0.4038
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0027 0.0219 0.0783
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0017 0.0107 0.0384
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0009 0.0018 0.0065
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0017 0.0107 0.0384
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0023 0.0172 0.0467
Loa Loa (eye worm) hypothetical protein 0.0044 0.04 0.1086
Loa Loa (eye worm) hypothetical protein 0.0036 0.0312 0.0846
Leishmania major UDP-galactopyranose mutase 0.0009 0.0021 0.0104
Trichomonas vaginalis glutathione reductase, putative 0.0027 0.0219 0.0372
Trichomonas vaginalis glutaminase, putative 0.0096 0.0966 0.1644
Loa Loa (eye worm) bromodomain containing protein 0.0009 0.0024 0.0066
Schistosoma mansoni jun-related protein 0.0225 0.2368 0.2368
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0071 0.0691 0.0691
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0051 0.0473 0.1284
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0012 0.0057 0.0057
Toxoplasma gondii NADPH-glutathione reductase 0.0027 0.0219 0.1105
Trichomonas vaginalis myo inositol monophosphatase, putative 0.002 0.0144 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.0079
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0056 0.0529 0.2672
Trypanosoma cruzi Heat shock protein 83, putative 0.0046 0.0424 0.2139
Brugia malayi ImpB/MucB/SamB family protein 0.0018 0.0121 0.0342
Mycobacterium leprae Probable two component sensor kinase MprB 0.0009 0.0016 0.0076
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0099 0.0995 0.2701
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.007 0.0686 0.0686
Brugia malayi Cytochrome P450 family protein 0.0053 0.0498 0.141
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0085 0.0085
Loa Loa (eye worm) PHD-finger family protein 0.0009 0.0017 0.0045
Schistosoma mansoni heat shock protein 0.0046 0.0424 0.0424
Brugia malayi nuclear receptor RXR 0.0099 0.0995 0.2818
Trypanosoma brucei RNA helicase, putative 0.0026 0.0206 0.1038
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.0079
Loa Loa (eye worm) hypothetical protein 0.0011 0.0045 0.0122
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0027 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0061 0.0582 0.1581
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0009 0.0016 0.0302
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0141 0.0714
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0098 0.0994 0.5019
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0019 0.0127 0.0606
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0017 0.0107 0.0384
Plasmodium vivax importin-beta 2, putative 0.0032 0.0273 0.1517
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0017 0.0107 0.0384
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.001 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0064 0.0616 0.0616
Echinococcus multilocularis glycine receptor subunit beta 0.0108 0.1103 0.1103
Giardia lamblia Grp94/Hsp90 0.0043 0.0387 0.0988
Brugia malayi Pre-SET motif family protein 0.0025 0.0194 0.0549
Mycobacterium ulcerans beta-lactamase 0.0009 0.0018 0.0065
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0017 0.0107 0.0383
Echinococcus granulosus GPCR family 2 0.0062 0.0593 0.0593
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0187 0.1954 0.5534
Onchocerca volvulus 0.0328 0.3497 1
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0017 0.0107 0.0384
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0105 0.0178
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0027 0.0219 0.0219
Schistosoma mansoni thyroid hormone receptor 0.0378 0.4038 0.4038
Entamoeba histolytica 90 kDa heat shock protein, putative 0.003 0.0251 0.0427
Toxoplasma gondii type I fatty acid synthase, putative 0.0019 0.0132 0.0665
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0204 0.103
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0057 0.0542 0.1939
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0025 0.0195 0.0986
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0235 0.2485 0.2485
Loa Loa (eye worm) hypothetical protein 0.0133 0.1372 0.3724
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0032 0.0274 0.0743
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0085 0.0085
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0088 0.088 0.088
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0024 0.0178 0.0483
Loa Loa (eye worm) hypothetical protein 0.0331 0.3532 0.9585
Brugia malayi tailless protein 0.0088 0.088 0.2492
Loa Loa (eye worm) hypothetical protein 0.0018 0.0121 0.0328
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0108 0.1103 0.1103
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0207 0.0352
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0065 0.0185
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.002 0.0144 0.0729
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0085 0.043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0115 0.0311
Brugia malayi jmjC domain containing protein 0.0057 0.0537 0.1519
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0009 0.0017 0.0061
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.007 0.0686 0.0686
Toxoplasma gondii leucyl aminopeptidase LAP 0.0056 0.0529 0.2672
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0017 0.0107 0.0384
Echinococcus multilocularis jun protein 0.0276 0.2932 0.2932
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.017 0.0858
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0009 0.0017 0.0061
Schistosoma mansoni cpg binding protein 0.0054 0.0514 0.0514
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.007 0.0686 0.1942
Plasmodium falciparum carbonic anhydrase 0.0025 0.0195 0.1082
Brugia malayi nuclear hormone receptor family member odr-7 0.0088 0.088 0.2492
Onchocerca volvulus 0.0009 0.0021 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.017 0.0858
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0017 0.0107 0.0384
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0025 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0099 0.0995 0.2701
Schistosoma mansoni nAChR subunit 0.007 0.0686 0.0686
Echinococcus granulosus carbonic anhydrase II 0.0068 0.0659 0.0659
Loa Loa (eye worm) doublecortin family protein 0.0064 0.0616 0.1671
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0071 0.0691 0.1956
Onchocerca volvulus 0.0017 0.0107 0.0305
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0066 0.0334
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Treponema pallidum NADH oxidase 0.0027 0.0219 0.0559
Mycobacterium tuberculosis Probable lipase LipD 0.0009 0.0018 0.0065
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0122 0.1252 0.1252
Treponema pallidum exodeoxyribonuclease (exoA) 0.0025 0.0195 0.0498
Brugia malayi Carboxylesterase family protein 0.0041 0.0371 0.1051
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.018 0.0911
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0023 0.017 0.0858
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.018 0.0511
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0066 0.0334
Echinococcus granulosus thyroid hormone receptor alpha 0.0088 0.088 0.088
Brugia malayi Heterochromatin protein 1 0.0033 0.0278 0.0787
Echinococcus granulosus tumor protein p63 0.0728 0.7851 0.7851
Echinococcus granulosus transcription factor Dp 1 0.0035 0.0298 0.0298
Schistosoma mansoni ran 0.0024 0.018 0.018
Schistosoma mansoni acetylcholine receptor subunit beta 0.0032 0.0274 0.0274
Brugia malayi RNA, U transporter 1 0.0092 0.0923 0.2615
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.003 0.0251 0.0251
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0207 0.0352
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.007 0.0686 0.1942
Entamoeba histolytica hypothetical protein 0.0122 0.1252 0.2131
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0105 0.0178
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0027 0.0219 0.0619
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0107 0.0542
Echinococcus granulosus cyclic AMP responsive element binding protein 0.0008 0.0004 0.0004
Trypanosoma cruzi cysteine peptidase, putative 0.0023 0.017 0.0858
Entamoeba histolytica hypothetical protein 0.0038 0.0333 0.0567
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0018 0.0115 0.0413
Echinococcus multilocularis leucyl aminopeptidase 0.0011 0.0042 0.0042
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.007 0.0679 0.0679
Entamoeba histolytica hypothetical protein 0.0122 0.1252 0.2131
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0027 0.0219 0.1105
Echinococcus granulosus zinc finger protein 0.0013 0.0065 0.0065
Plasmodium falciparum glutathione reductase 0.0027 0.0219 0.1213
Brugia malayi fructose-1,6-bisphosphatase 0.0189 0.198 0.5606
Brugia malayi hypothetical protein 0.0032 0.0274 0.0775
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0179 0.1872 0.6701
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0204 0.103
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0023 0.0172 0.0172
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0012 0.0057 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0204 0.103
Schistosoma mansoni nAChR subunit 0.0032 0.0274 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0004 0.0004
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0019 0.0133 0.0362
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0002 0.0004
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.0189 0.198 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0333 0.0904
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0002 0.0004
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0038 0.0333 0.0943
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.002 0.0144 0.0729
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0346 0.1746
Loa Loa (eye worm) hypothetical protein 0.0041 0.0371 0.1007
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0107 0.054
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0017 0.0107 0.0382
Entamoeba histolytica myo-inositol monophosphatase, putative 0.002 0.0144 0.0246
Brugia malayi hypothetical protein 0.0099 0.0995 0.2818
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0009 0.0021 0.0114
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.001 0.003 0.003
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0187 0.1954 0.1954
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0187 0.1954 0.1954
Echinococcus granulosus GA binding protein alpha chain 0.0032 0.0265 0.0265
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0009 0.0023 0.0039
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0002 0.0004
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0009 0.0018 0.0065
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0008 0.0004 0.0018
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.021 0.057
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0015 0.0088 0.0088
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0994 0.1691
Brugia malayi steroid hormone receptor 0.0187 0.1954 0.5534
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.001 0.003 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0105 0.0178
Echinococcus granulosus jun protein 0.0276 0.2932 0.2932
Brugia malayi MH2 domain containing protein 0.008 0.0791 0.2239
Schistosoma mansoni transcription factor LCR-F1 0.0122 0.1252 0.1252
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0025 0.0195 0.0986
Trypanosoma cruzi DNA polymerase kappa, putative 0.0026 0.0204 0.103
Leishmania major GTP-binding protein, putative 0.0024 0.018 0.0911
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0007 0.0002 0.0004
Trypanosoma brucei unspecified product 0.0013 0.0059 0.0296
Echinococcus granulosus hyperpolarization activated cyclic 0.001 0.003 0.003
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.0624 0.2236
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0117 0.0589
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0088 0.088 0.088
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0011 0.0042 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0121 0.0206
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0104 0.1052 0.1052
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0009 0.0016 0.0076
Loa Loa (eye worm) inositol-1 0.002 0.0144 0.0392
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0019 0.0133 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.0079
Mycobacterium ulcerans DNA polymerase IV 0.0026 0.0204 0.073
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.007 0.0686 0.1942
Loa Loa (eye worm) hypothetical protein 0.0011 0.004 0.0109
Echinococcus multilocularis lamin 0.0024 0.0178 0.0178
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0075 0.0739 0.2647
Echinococcus granulosus cyclic nucleotide gated cation channel 0.001 0.003 0.003
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0027 0.0219 0.1105
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.007 0.0686 0.1942
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0017 0.0107 0.0384
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0011 0.0042 0.0114
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0085 0.043
Echinococcus multilocularis RUN 0.0064 0.0616 0.0616
Echinococcus granulosus dna polymerase eta 0.0018 0.0121 0.0121
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.007 0.0686 0.1942
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0099 0.0995 0.0995
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0032 0.0274 0.0274
Toxoplasma gondii heat shock protein HSP90 0.0046 0.0424 0.2139
Schistosoma mansoni nuclear hormone receptor 0.0088 0.088 0.088
Echinococcus granulosus glycine receptor subunit alpha 1 0.0108 0.1103 0.1103
Schistosoma mansoni hypothetical protein 0.0548 0.5886 0.5886
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.0593 0.0593
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0187 0.1954 0.5304
Entamoeba histolytica heat shock protein 90, putative 0.0046 0.0424 0.0721
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0346 0.0588
Plasmodium falciparum protoporphyrinogen oxidase 0.0009 0.0021 0.0114
Echinococcus granulosus nAChR subunit 0.007 0.0686 0.0686
Echinococcus multilocularis acetylcholinesterase 0.0104 0.1052 0.1052
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0027 0.0219 0.4134
Brugia malayi jmjC domain containing protein 0.0015 0.0085 0.0241
Brugia malayi small heat shock protein 0.0321 0.3413 0.9663
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0273 0.1381
Schistosoma mansoni camp-response element binding protein-related 0.0008 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0328 0.3497 0.9491
Entamoeba histolytica hypothetical protein 0.0026 0.0207 0.0352
Echinococcus multilocularis zinc finger protein 0.0013 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0108 0.1103 0.2993
Schistosoma mansoni hypothetical protein 0.0122 0.1252 0.1252
Schistosoma mansoni retinoic acid receptor RXR 0.0241 0.255 0.255
Loa Loa (eye worm) LGC-31 protein 0.007 0.0686 0.1861
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.001 0.003 0.0109
Brugia malayi CXXC zinc finger family protein 0.0051 0.0473 0.134
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0179 0.1872 0.8915
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0107 0.0107
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0017 0.0107 0.0384
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0068 0.0659 0.1789
Brugia malayi acetyltransferase, GNAT family protein 0.0081 0.0808 0.2288
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0021 0.0114
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.018 0.018
Brugia malayi ecdysone receptor 0.0088 0.088 0.2492
Trichomonas vaginalis receptor histidine kinase, putative 0.0009 0.0023 0.0039
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0025 0.0195 0.0552
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0088 0.088 0.088
Onchocerca volvulus 0.003 0.0252 0.0721
Schistosoma mansoni ap endonuclease 0.0025 0.0195 0.0195
Brugia malayi hypothetical protein 0.0032 0.0274 0.0775
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.007 0.0686 0.0686
Mycobacterium ulcerans aldehyde dehydrogenase 0.0075 0.0739 0.2647
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0025 0.0195 0.053
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0023 0.017 0.017
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0498 0.2515
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0019 0.0133 0.0133
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0017 0.0107 0.0383
Loa Loa (eye worm) acetylcholine receptor protein 0.0032 0.0274 0.0743
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0085 0.0085
Schistosoma mansoni heat shock protein 0.0046 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0017 0.0107 0.0384
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0018 0.0121 0.0121
Echinococcus multilocularis dna polymerase eta 0.0018 0.0121 0.0121
Echinococcus multilocularis GPCR, family 2 0.0062 0.0593 0.0593
Schistosoma mansoni fos transcription factor-related 0.0008 0.0004 0.0004
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.018 0.018
Entamoeba histolytica deoxycytidyl transferase, putative 0.0018 0.0121 0.0205
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0009 0.002 0.002
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0068 0.0659 0.3329
Echinococcus multilocularis leucyl aminopeptidase 0.0011 0.0042 0.0042
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0025 0.0195 0.0552
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0367 0.3915 0.6664
Loa Loa (eye worm) hypothetical protein 0.0089 0.089 0.2414
Mycobacterium leprae Polyketide synthase Pks13 0.0027 0.0211 0.1007
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0038 0.0333 0.0333
Plasmodium vivax heat shock protein 86, putative 0.0046 0.0424 0.235
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Brugia malayi glutathione reductase 0.0079 0.078 0.2209
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0019 0.0133 0.0133
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0105 0.0178
Mycobacterium leprae conserved hypothetical protein 0.0009 0.0018 0.0086
Leishmania major DNA polymerase eta, putative 0.0018 0.0121 0.061
Brugia malayi Endoplasmin precursor 0.0046 0.0424 0.1199
Brugia malayi hypothetical protein 0.0083 0.0825 0.2336
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0367 0.3915 0.6664
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0018 0.01
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0011 0.0042 0.0213
Loa Loa (eye worm) hypothetical protein 0.0195 0.2044 0.5548
Schistosoma mansoni amine oxidase 0.0009 0.0021 0.0021
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0624 0.2236
Loa Loa (eye worm) bZIP transcription factor family protein 0.0008 0.0004 0.001
Brugia malayi ecdysteroid receptor 0.0187 0.1954 0.5534
Echinococcus multilocularis cpg binding protein 0.0054 0.0514 0.0514
Brugia malayi conserved hypotetical protein 0.0088 0.088 0.2492
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0533 0.2691
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0021 0.0114
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.011 0.112 0.1906
Loa Loa (eye worm) hypothetical protein 0.0187 0.1954 0.5304
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0017 0.0107 0.0384
Schistosoma mansoni leucine aminopeptidase 0.0011 0.0042 0.0042
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0018 0.0121 0.0433
Loa Loa (eye worm) hypothetical protein 0.0038 0.0333 0.0904
Echinococcus multilocularis fructose 1,6 bisphosphatase 1 0.0189 0.198 0.198
Mycobacterium tuberculosis Carboxylesterase LipT 0.0264 0.2793 1
Schistosoma mansoni cellular tumor antigen P53 0.0107 0.1082 0.1082
Loa Loa (eye worm) hypothetical protein 0.0018 0.0121 0.0329
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0498 0.1351
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Trypanosoma brucei heat shock protein, putative 0.0046 0.0424 0.2139
Schistosoma mansoni steroid hormone receptor ad4bp 0.0187 0.1954 0.1954
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.007 0.0686 0.1861
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0025 0.019 0.0958
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0027 0.0219 0.0219
Trypanosoma brucei sedoheptulose-1,7-bisphosphatase 0.007 0.0687 0.3468
Trypanosoma brucei DNA polymerase eta, putative 0.0018 0.0121 0.061
Toxoplasma gondii sedoheptulose-1,7-bisphosphatase 0.007 0.0687 0.3468
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0187 0.1954 0.1954
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0023 0.017 0.0858
Brugia malayi TAR-binding protein 0.0064 0.0621 0.1759
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0034 0.0291 0.1468
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0009 0.0021 0.0021
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0017 0.0107 0.029
Brugia malayi PHD-finger family protein 0.0015 0.009 0.0254
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0019 0.0133 0.0133
Loa Loa (eye worm) glutaminase 2 0.0096 0.0966 0.2622
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0204 0.103
Mycobacterium ulcerans dehydrogenase 0.0009 0.0021 0.0074
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0088 0.088 0.2517
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0019 0.0127 0.0456
Schistosoma mansoni nAChR subunit 0.0032 0.0274 0.0274
Schistosoma mansoni DNA polymerase eta 0.0018 0.0121 0.0121
Plasmodium vivax thioredoxin reductase, putative 0.0079 0.078 0.4329
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0013 0.0068 0.0068
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0616 0.0616
Trypanosoma brucei heat shock protein, putative 0.0046 0.0424 0.2139
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.001 0.003 0.003
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0085 0.043
Brugia malayi hypothetical protein 0.0064 0.0616 0.1743
Echinococcus granulosus leucyl aminopeptidase 0.0011 0.0042 0.0042
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0009 0.0018 0.0049
Loa Loa (eye worm) hypothetical protein 0.0088 0.088 0.2389
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0098 0.0994 0.5019
Schistosoma mansoni neuroligin 3 (S09 family) 0.0041 0.0371 0.0371
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0047 0.0437 0.0744
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0012 0.0049 0.0236
Echinococcus granulosus L aminoadipate semialdehyde 0.0061 0.0582 0.0582
Echinococcus granulosus cpg binding protein 0.0054 0.0514 0.0514
Mycobacterium ulcerans two component sensor kinase MprB 0.0009 0.0016 0.0057
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0136 0.0752
Brugia malayi follicle stimulating hormone receptor 0.018 0.1885 0.5337
Echinococcus granulosus geminin 0.0548 0.5886 0.5886
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0994 0.1691
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.003 0.0251 0.0251
Trypanosoma brucei hypothetical protein, conserved 0.0009 0.0018 0.0091
Loa Loa (eye worm) heat shock protein 90 0.0046 0.0424 0.115
Loa Loa (eye worm) hypothetical protein 0.0187 0.1954 0.5304
Schistosoma mansoni lozenge 0.0041 0.037 0.037
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0017 0.0107 0.0384
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0187 0.1954 0.5304
Brugia malayi Thioredoxin reductase 0.0079 0.078 0.2209
Onchocerca volvulus 0.0064 0.0616 0.176
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0008 0.0007 0.0037
Echinococcus multilocularis neuroligin 0.0041 0.0371 0.0371
Giardia lamblia Heat shock protein HSP 90-alpha 0.0046 0.0424 0.1082
Schistosoma mansoni 60S ribosomal protein L21 0.0008 0.0008 0.0008
Echinococcus granulosus cGMP dependent protein kinase 0.0008 0.0004 0.0004
Echinococcus granulosus carboxylesterase 5A 0.0104 0.1052 0.1052
Echinococcus multilocularis mitogen activated protein kinase 0.0098 0.0994 0.0994
Echinococcus multilocularis snurportin 1 0.0345 0.3684 0.3684
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.001 0.003 0.0169
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0047 0.0079
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0085 0.043
Echinococcus granulosus nuclear receptor nhr 48 0.0088 0.088 0.088
Loa Loa (eye worm) fatty acid synthase 0.0018 0.0113 0.0306
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0009 0.0016 0.0076
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0027 0.0219 0.4134
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0027 0.0212 0.0212
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0085 0.0231
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0053 0.0498 0.1782
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0027 0.0212 0.0212
Schistosoma mansoni hypothetical protein 0.0562 0.6048 0.6048
Brugia malayi Bromodomain containing protein 0.0018 0.012 0.034
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0683
Loa Loa (eye worm) beta-lactamase 0.0009 0.0018 0.0049
Echinococcus multilocularis nAChR subunit 0.007 0.0686 0.0686
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0136 0.0685
Schistosoma mansoni nuclear hormone receptor 0.0187 0.1954 0.1954
Toxoplasma gondii heat shock protein 75, putative 0.003 0.0251 0.1267
Echinococcus granulosus glycine receptor subunit alpha 1 0.0108 0.1103 0.1103
Schistosoma mansoni nAChR subunit 0.007 0.0686 0.0686
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0009 0.0016 0.0057
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0018 0.0121 0.0121
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0207 0.0352
Trichomonas vaginalis heat shock protein, putative 0.0034 0.0287 0.0489
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Schistosoma mansoni neurotransmitter gated ion channel 0.0032 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0038 0.0333 0.0904
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0041 0.0371 0.0632
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0187 0.1954 0.5534
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.001 0.003 0.003
Brugia malayi PAS domain containing protein 0.0024 0.0186 0.0527
Loa Loa (eye worm) hypothetical protein 0.0104 0.1052 0.2856
Trypanosoma cruzi cruzipain precursor, putative 0.0023 0.017 0.0858
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0051 0.0473 0.134
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0017 0.0107 0.0594
Schistosoma mansoni endoplasmin 0.0046 0.0424 0.0424
Brugia malayi hypothetical protein 0.0013 0.006 0.0169
Schistosoma mansoni aldehyde dehydrogenase 0.0075 0.0739 0.0739
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0108 0.1103 0.1103
Entamoeba histolytica protein tyrosine phosphatase, putative 0.011 0.112 0.1906
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0004 0.0004
Echinococcus multilocularis carbonic anhydrase II 0.0068 0.0659 0.0659
Echinococcus multilocularis heat shock protein 90 0.0039 0.0346 0.0346
Giardia lamblia DINP protein human, muc B family 0.002 0.0141 0.0361
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0068 0.0068
Echinococcus granulosus fos transcription factor 0.0008 0.0004 0.0004
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.001 0.003 0.003
Echinococcus granulosus dnaJ subfamily B 0.0562 0.6048 0.6048
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.001 0.0025 0.0137
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0011 0.0042 0.0119
Brugia malayi hypoxia-induced factor 1 0.0075 0.0741 0.2099
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.017 0.0858
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0008 0.0004 0.0004
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.007 0.0686 0.1861
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.007 0.0686 0.1942
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0017 0.0107 0.0384
Mycobacterium ulcerans polyketide synthase Pks13 0.0027 0.0211 0.0757
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0194 0.0194
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.006 0.0572 0.2891
Toxoplasma gondii ABC1 family protein 0.0009 0.0018 0.0091
Trypanosoma brucei heat shock protein 90, putative 0.0046 0.0424 0.2139
Brugia malayi Nuclear hormone receptor-like 1 0.0099 0.0995 0.2818
Loa Loa (eye worm) MH2 domain-containing protein 0.008 0.0791 0.2146
Trichomonas vaginalis ap endonuclease, putative 0.0025 0.0195 0.0332
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.006 0.0572 0.0572
Loa Loa (eye worm) CHromoDomain protein family member 0.0009 0.002 0.0054
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0085 0.0085
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0018 0.0115 0.0413
Echinococcus multilocularis acetylcholinesterase 0.0104 0.1052 0.1052
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0424 0.2139
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0041 0.0371 0.0371
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.0009 0.0032
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0108 0.1103 0.1103
Brugia malayi hypothetical protein 0.0217 0.2286 0.6472
Loa Loa (eye worm) hypothetical protein 0.0009 0.0018 0.0049
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0075 0.0739 0.3734
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0039 0.0346 0.0346
Echinococcus multilocularis tumor protein p63 0.0728 0.7851 0.7851
Schistosoma mansoni thyroid hormone receptor 0.0378 0.4038 0.4038
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Toxoplasma gondii fructose-bisphospatase I 0.007 0.0687 0.3468
Loa Loa (eye worm) hypothetical protein 0.0009 0.0021 0.0056
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0011 0.0042 0.0213
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0007 0.0002 0.0004
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.007 0.0686 0.0686
Echinococcus multilocularis heat shock protein 90 0.0046 0.0424 0.0424
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.007 0.0687 0.3468
Schistosoma mansoni RAR-like nuclear receptor 0.0187 0.1954 0.1954
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0009 0.0018 0.0051
Loa Loa (eye worm) hypothetical protein 0.0009 0.0018 0.0049
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.001 0.003 0.003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0274 0.0775
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0085 0.0085
Echinococcus multilocularis mitogen activated protein kinase 3 0.0098 0.0994 0.0994
Loa Loa (eye worm) hypothetical protein 0.0187 0.1954 0.5304
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0043 0.0387 0.1843
Onchocerca volvulus 0.007 0.0686 0.1961
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0009 0.0016 0.0057
Echinococcus multilocularis fos transcription factor 0.0008 0.0004 0.0004
Mycobacterium ulcerans esterase/lipase LipP 0.0009 0.0018 0.0065
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0187 0.1954 0.1954
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0136 0.0752
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0017 0.0107 0.0384
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.002 0.0144 0.2726
Schistosoma mansoni camp-response element binding protein 0.0008 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0041 0.0371 0.1007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0099 0.0269
Schistosoma mansoni hypothetical protein 0.0133 0.1372 0.1372
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0027 0.0219 0.1213
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0017 0.0107 0.054
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0098 0.0994 0.5019
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0017 0.0107 0.0384
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0079 0.0401
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0032 0.0274 0.0775
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.002 0.0144 0.0729
Mycobacterium leprae conserved hypothetical protein 0.0017 0.0107 0.051
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.007 0.0686 0.1942
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0125 0.0125
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0014 0.0077 0.0277
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0291 0.1468
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.006 0.0572 0.0974
Toxoplasma gondii isocitrate dehydrogenase 0.001 0.003 0.0154
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0008 0.0007 0.0037
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0009 0.0021 0.0074
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0041 0.0371 0.0371
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.011 0.112 0.1906
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0011 0.0042 0.0213
Schistosoma mansoni nAChR subunit 0.007 0.0686 0.0686
Brugia malayi Inositol-1 0.002 0.0144 0.0408
Schistosoma mansoni peptidase Clp (S14 family) 0.0023 0.017 0.017
Echinococcus multilocularis lamin dm0 0.0024 0.0178 0.0178
Schistosoma mansoni voltage-gated potassium channel 0.0055 0.0524 0.0524
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0108 0.1103 0.1103
Loa Loa (eye worm) hypothetical protein 0.0041 0.0371 0.1007
Brugia malayi beta-lactamase family protein 0.0009 0.0018 0.0051
Brugia malayi Carboxylesterase family protein 0.0104 0.1052 0.2979
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.001 0.003 0.003
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.018 0.1001
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0009 0.0021 0.0074
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0019 0.0127 0.0456
Brugia malayi hypothetical protein 0.0088 0.088 0.2492
Trypanosoma cruzi DNA polymerase kappa, putative 0.0026 0.0204 0.103
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0057 0.0537 0.0537
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0273 0.0273
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0075 0.0739 0.0739
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0387 0.0659
Leishmania major hypothetical protein, conserved 0.0015 0.0085 0.043
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0009 0.0016 0.0057
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0011 0.0045 0.0045
Plasmodium vivax heat shock protein, putative 0.0173 0.1802 1
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0009 0.0016 0.0057
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.007 0.0687 0.3468
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0017 0.0107 0.0384
Mycobacterium ulcerans putative regulatory protein 0.0018 0.0117 0.0419
Loa Loa (eye worm) hypothetical protein 0.0011 0.004 0.0109
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0274 0.0775
Treponema pallidum fructose-bisphosphate aldolase 0.0367 0.3915 1
Mycobacterium tuberculosis Probable dehydrogenase 0.018 0.1881 0.6734
Echinococcus multilocularis nAChR subunit 0.0038 0.0333 0.0333
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0027 0.0212 0.0212
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0207 0.1045
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0621 0.0621
Plasmodium vivax hypothetical protein, conserved 0.001 0.0025 0.0137
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0546 0.5874 1
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0018 0.0115 0.0195
Brugia malayi hypothetical protein 0.0041 0.0371 0.1051
Onchocerca volvulus Protein ultraspiracle homolog 0.0187 0.1954 0.5589
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0025 0.0195 0.0498
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0023 0.017 0.3209
Brugia malayi cytoplasmic intermediate filament protein 0.0013 0.0059 0.0166
Entamoeba histolytica acetyltransferase, GNAT family 0.0022 0.0157 0.0268
Trypanosoma cruzi trypanothione reductase, putative 0.0079 0.078 0.3941
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.002 0.0144 0.0729
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.001 0.003 0.0154
Brugia malayi Cytochrome P450 family protein 0.0027 0.021 0.0595
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0546 0.5874 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0367 0.3915 0.6664
Plasmodium falciparum cGMP-dependent protein kinase 0.0008 0.0004 0.002
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0011 0.0042 0.0213
Mycobacterium ulcerans aldehyde dehydrogenase 0.0075 0.0739 0.2647
Trypanosoma brucei cytochrome P450, putative 0.0053 0.0498 0.2515
Mycobacterium tuberculosis Conserved protein 0.0009 0.0018 0.0065
Onchocerca volvulus 0.007 0.0686 0.1961
Loa Loa (eye worm) hypothetical protein 0.0299 0.3179 0.8628
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.021 0.1163
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.017 0.0858
Mycobacterium tuberculosis Conserved hypothetical protein 0.0018 0.0121 0.0432
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.018 0.1881 0.6734
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0047 0.0079
Loa Loa (eye worm) hypothetical protein 0.0076 0.075 0.2036
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0994 0.0994
Loa Loa (eye worm) hypothetical protein 0.0187 0.1954 0.5304
Schistosoma mansoni microtubule-associated protein tau 0.0925 1 1
Brugia malayi bZIP transcription factor family protein 0.0008 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0187 0.1954 0.1954
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0032 0.0273 0.0742
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0088 0.088 0.2492
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0141 0.0714
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0187 0.1954 0.1954
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.011 0.112 0.1906
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0135 0.0682
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0621 0.1686
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0051 0.0473 0.0473
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0008 0.0007 0.0032
Loa Loa (eye worm) hypothetical protein 0.0009 0.0021 0.0056
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.006 0.0572 0.1621
Loa Loa (eye worm) acetyltransferase 0.0081 0.0808 0.2193
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.001 0.003 0.0051
Loa Loa (eye worm) hypothetical protein 0.0187 0.1954 0.5304
Echinococcus granulosus endoplasmin 0.0043 0.0387 0.0387
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0025 0.019 0.0323
Loa Loa (eye worm) isocitrate dehydrogenase 0.001 0.003 0.0083
Trichomonas vaginalis penicillin-binding protein, putative 0.0009 0.0018 0.0031
Plasmodium falciparum M17 leucyl aminopeptidase 0.0056 0.0529 0.2935
Brugia malayi bZIP transcription factor family protein 0.0276 0.2932 0.8303
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Mycobacterium ulcerans DNA polymerase IV 0.0026 0.0204 0.073
Onchocerca volvulus 0.007 0.0686 0.1961
Echinococcus granulosus histone acetyltransferase KAT2B 0.0078 0.0773 0.0773
Echinococcus multilocularis protoporphyrinogen oxidase 0.0009 0.0021 0.0021
Echinococcus multilocularis BC026374 protein (S09 family) 0.0041 0.0371 0.0371
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0032 0.0274 0.0274
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0273 0.0273
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0015 0.0084 0.0301
Treponema pallidum heat shock protein 90 0.0043 0.0387 0.0988
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0017 0.0107 0.0384
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0061 0.0582 0.0582
Schistosoma mansoni carbonic anhydrase 0.0025 0.0195 0.0195
Mycobacterium ulcerans aldehyde dehydrogenase 0.0075 0.0739 0.2647
Trichomonas vaginalis penicillin-binding protein, putative 0.0009 0.0018 0.0031
Schistosoma mansoni loxhd1 0.0064 0.0616 0.0616
Brugia malayi CHD4 protein 0.0009 0.002 0.0056
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0085 0.0085
Loa Loa (eye worm) runx1 0.0041 0.037 0.1003
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0017 0.0107 0.0384
Loa Loa (eye worm) hypothetical protein 0.003 0.0249 0.0677
Echinococcus granulosus carbonic anhydrase 0.0025 0.0195 0.0195
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.001 0.0031 0.0113
Loa Loa (eye worm) RNA binding protein 0.0064 0.0621 0.1686
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0187 0.1954 0.1954
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0018 0.0115 0.0549
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0017 0.0107 0.0384
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0204 0.103
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0085 0.0472
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0025 0.0194 0.0194
Brugia malayi Carboxylesterase family protein 0.0041 0.0371 0.1051
Toxoplasma gondii type I fatty acid synthase, putative 0.0013 0.0059 0.0299
Trichomonas vaginalis spcc417.12 protein, putative 0.0041 0.0371 0.0632
Echinococcus multilocularis L aminoadipate semialdehyde 0.0061 0.0582 0.0582
Echinococcus granulosus peptidase Clp S14 family 0.0015 0.0084 0.0084
Entamoeba histolytica hypothetical protein 0.0122 0.1252 0.2131
Echinococcus multilocularis geminin 0.0548 0.5886 0.5886
Echinococcus granulosus tar DNA binding protein 0.0064 0.0621 0.0621
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.001 0.003 0.0154
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0062 0.0593 0.0593
Loa Loa (eye worm) hypothetical protein 0.0008 0.0004 0.001
Schistosoma mansoni hypothetical protein 0.0062 0.0593 0.0593
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0105 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.0079
Echinococcus granulosus acetylcholinesterase 0.0104 0.1052 0.1052
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0015 0.0085 0.1604
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0017 0.0109 0.0391
Schistosoma mansoni rab6-interacting 0.0064 0.0616 0.0616
Loa Loa (eye worm) hypothetical protein 0.0088 0.088 0.2389
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0071 0.0691 0.0691
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0019 0.0133 0.0133
Onchocerca volvulus 0.0191 0.2002 0.5724
Echinococcus multilocularis transfer RNA-Lys 0.0018 0.0117 0.0117
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0019 0.0127 0.0606
Onchocerca volvulus 0.007 0.0686 0.1961
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0015 0.0081 0.0229
Brugia malayi amine oxidase, flavin-containing family protein 0.0009 0.0021 0.0058
Mycobacterium ulcerans heat shock protein 90 0.0043 0.0387 0.1385
Loa Loa (eye worm) hypothetical protein 0.0009 0.0021 0.0056
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0015 0.0083 0.0395
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0041 0.0371 0.0371
Schistosoma mansoni importin beta-1 0.0032 0.0273 0.0273
Toxoplasma gondii cytochrome p450 superfamily protein 0.0017 0.0107 0.0542
Trichomonas vaginalis inositol monophosphatase, putative 0.002 0.0144 0.0246
Brugia malayi hypothetical protein 0.0088 0.088 0.2492
Echinococcus granulosus cGMP dependent protein kinase 1 0.0008 0.0004 0.0004
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0011 0.0042 0.0213
Schistosoma mansoni hypothetical protein 0.0025 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Loa Loa (eye worm) hypothetical protein 0.001 0.003 0.0081
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.002 0.014 0.0396
Giardia lamblia Fructose-bisphosphate aldolase 0.0367 0.3915 1
Trypanosoma brucei heat shock protein 90, putative 0.0046 0.0424 0.2139
Loa Loa (eye worm) hypothetical protein 0.0083 0.0825 0.2239
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0187 0.1954 0.5534
Schistosoma mansoni voltage-gated potassium channel 0.0055 0.0524 0.0524
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0085 0.0085
Brugia malayi ImpB/MucB/SamB family protein 0.0018 0.0121 0.0342
Mycobacterium ulcerans two component regulator - sensor kinase 0.0009 0.0016 0.0057
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0025 0.0195 0.0529
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.007 0.0686 0.0686
Mycobacterium tuberculosis Putative ferredoxin reductase 0.018 0.1881 0.6734
Brugia malayi hypothetical protein 0.0008 0.0004 0.001
Echinococcus granulosus BC026374 protein S09 family 0.0041 0.0371 0.0371
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0009 0.0018 0.0065
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0008 0.0004 0.0004
Brugia malayi intermediate filament protein 0.0024 0.0178 0.0504
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Leishmania major protein kinase, putative 0.0014 0.0072 0.0366
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0009 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.007 0.0686 0.1861
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0994 0.1691
Trypanosoma brucei DNA polymerase IV, putative 0.0026 0.0204 0.103
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0068 0.0659 0.3329
Loa Loa (eye worm) hypothetical protein 0.0032 0.0274 0.0743
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.001 0.003 0.003
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0047 0.0437 0.0744
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.001 0.003 0.0154
Echinococcus granulosus fructose 16 bisphosphatase 1 0.0189 0.198 0.198
Loa Loa (eye worm) hypothetical protein 0.0099 0.0995 0.2701
Onchocerca volvulus 0.0009 0.0018 0.0052
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0056 0.0529 1
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0017 0.0107 0.2022
Echinococcus multilocularis ecdysone induced protein 78C 0.0187 0.1954 0.1954
Trichomonas vaginalis bromodomain-containing protein, putative 0.0025 0.019 0.0323
Schistosoma mansoni cytochrome P450 0.0017 0.0107 0.0107
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0025 0.0195 0.0986
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0621 0.0621
Trypanosoma cruzi DNA polymerase eta, putative 0.0018 0.0121 0.061
Schistosoma mansoni chromobox protein 0.0033 0.0278 0.0278
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0018 0.0115 0.0413
Trypanosoma brucei DNA polymerase IV, putative 0.0026 0.0204 0.103
Onchocerca volvulus 0.0017 0.0105 0.0301
Mycobacterium ulcerans polyketide synthase Pks9 0.0012 0.0049 0.0177
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0076 0.075 0.2124
Leishmania major hypothetical protein, conserved 0.0056 0.0533 0.2691
Brugia malayi nuclear receptor NHR-88 0.0187 0.1954 0.5534
Loa Loa (eye worm) bZIP transcription factor family protein 0.0008 0.0004 0.001
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0273 0.1381
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0015 0.008 0.0286
Schistosoma mansoni acetylcholine receptor-related 0.0032 0.0274 0.0274
Echinococcus granulosus glycine receptor subunit beta 0.0108 0.1103 0.1103
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0191 0.2004 0.2004
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0017 0.0107 0.0383
Brugia malayi bZIP transcription factor family protein 0.0008 0.0004 0.001
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0107 0.0542
Schistosoma mansoni coup transcription factor 0.0187 0.1954 0.1954
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0088 0.088 0.088
Plasmodium falciparum endoplasmin, putative 0.0034 0.0287 0.1595
Mycobacterium tuberculosis Probable oxidoreductase 0.02 0.21 0.7517
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0023 0.017 0.3209
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0108 0.1103 0.1103
Echinococcus granulosus Polycystic kidney disease protein 0.0064 0.0616 0.0616
Schistosoma mansoni hypothetical protein 0.0062 0.0593 0.0593
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0367 0.3915 0.6664
Echinococcus granulosus ecdysone induced protein 78C 0.0187 0.1954 0.1954
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.006 0.0572 0.2891
Brugia malayi nuclear receptor NHR-88 0.0088 0.088 0.2492
Toxoplasma gondii hypothetical protein 0.0008 0.0007 0.0034
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0068 0.0659 0.1866
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0009 0.0016 0.0057
Brugia malayi Nuclear hormone receptor E75 0.0088 0.088 0.2492
Loa Loa (eye worm) hypothetical protein 0.0099 0.0995 0.2701
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.003 0.0251 0.0717
Echinococcus multilocularis heat shock protein 0.0046 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0041 0.0371 0.1007
Onchocerca volvulus 0.0008 0.0004 0.001
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0085 0.043
Plasmodium falciparum LCCL domain-containing protein 0.0064 0.0616 0.3415
Schistosoma mansoni nAChR subunit 0.007 0.0686 0.0686
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0079 0.078 0.2793
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0099 0.0995 0.0995
Leishmania major 0.0189 0.198 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0132 0.0357
Loa Loa (eye worm) hypothetical protein 0.002 0.0136 0.0368
Schistosoma mansoni hypothetical protein 0.0225 0.2368 0.2368
Plasmodium vivax JmjC domain containing protein 0.0015 0.0085 0.0472
Schistosoma mansoni bromodomain containing protein 0.0032 0.0268 0.0268
Trichomonas vaginalis esterase, putative 0.0009 0.0018 0.0031
Schistosoma mansoni terminal deoxycytidyl transferase 0.0018 0.0121 0.0121
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.001 0.003 0.0082
Leishmania major hypothetical protein, conserved 0.0009 0.0018 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0187 0.1954 0.5534
Onchocerca volvulus 0.0064 0.0616 0.176
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0367 0.3915 0.6664
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0088 0.088 0.088
Onchocerca volvulus Bile acid receptor homolog 0.0187 0.1954 0.5589
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0204 0.103
Loa Loa (eye worm) hypothetical protein 0.0009 0.0021 0.0056
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0621 0.0621
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0498 0.1351
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0018 0.0121 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0533 0.2691
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0219 0.1105
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0278 0.0473
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0023 0.017 0.0809
Trichomonas vaginalis sensor histidine kinase, putative 0.0009 0.0023 0.0039
Onchocerca volvulus Putative nachr subunit 0.007 0.0686 0.1961
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0108 0.1103 0.1103
Brugia malayi heat shock protein 90 0.0046 0.0424 0.1199
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0027 0.0219 0.0783
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0009 0.0018 0.0018
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0017 0.0107 0.0384
Echinococcus multilocularis carbonic anhydrase 0.0025 0.0195 0.0195
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.007 0.0686 0.1861
Chlamydia trachomatis cytosol aminopeptidase 0.0056 0.0529 1
Echinococcus granulosus lamin 0.0024 0.0178 0.0178
Mycobacterium tuberculosis Probable esterase LipL 0.0009 0.0018 0.0065
Mycobacterium ulcerans polyketide synthase 0.0018 0.0115 0.0413
Echinococcus multilocularis Protein lozenge 0.0041 0.037 0.037
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0621 0.1686
Schistosoma mansoni gliotactin 0.0041 0.0371 0.0371
Onchocerca volvulus 0.0009 0.0018 0.0052
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0011 0.0042 0.0213
Brugia malayi hypothetical protein 0.002 0.0136 0.0384
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.006 0.0572 0.2891
Mycobacterium tuberculosis Probable lipase LipE 0.0009 0.0018 0.0065
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0057 0.0537 0.0537
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0017 0.0107 0.0542
Echinococcus multilocularis expressed protein 0.0008 0.0004 0.0004
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0061 0.0582 0.1649
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.018 0.1881 0.6734
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0187 0.1954 0.5304
Loa Loa (eye worm) heterochromatin protein 1 0.0033 0.0278 0.0754
Plasmodium falciparum importin beta, putative 0.0032 0.0273 0.1517
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.0017 0.0107 0.0107
Echinococcus multilocularis 0.0017 0.0107 0.0107
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0025 0.019 0.1052
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0017 0.0107 0.0384
Brugia malayi Isocitrate dehydrogenase 0.001 0.003 0.0086
Schistosoma mansoni fructose-16-bisphosphatase-related 0.0189 0.198 0.198
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0195 0.2044 0.5788
Schistosoma mansoni voltage-gated potassium channel 0.001 0.003 0.003
Trypanosoma cruzi heat shock protein, putative 0.003 0.0251 0.1267
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0017 0.0107 0.0384
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0273 0.1381
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.0593 0.1609
Schistosoma mansoni polycystin 1-related 0.0064 0.0616 0.0616
Schistosoma mansoni nAChR subunit 0.007 0.0686 0.0686
Leishmania major cathepsin L-like protease 0.0023 0.017 0.0858
Plasmodium vivax glutathione reductase, putative 0.0079 0.078 0.4329
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0002 0.0004
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0056 0.0529 0.2935
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0079 0.0401
Schistosoma mansoni cpg binding protein 0.0051 0.0473 0.0473
Echinococcus granulosus chromobox protein 1 0.0033 0.0278 0.0278
Brugia malayi Cytochrome P450 family protein 0.0053 0.0498 0.141
Loa Loa (eye worm) hypothetical protein 0.0088 0.088 0.2389
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0023 0.017 0.3209
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.001 0.003 0.0082
Loa Loa (eye worm) carboxylesterase 0.0104 0.1052 0.2856
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0065 0.0624 0.3154
Leishmania major heat shock protein 83-1 0.0046 0.0424 0.2139
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.007 0.0686 0.1942
Loa Loa (eye worm) hypothetical protein 0.0014 0.0078 0.0211
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0009 0.0021 0.0114
Loa Loa (eye worm) carboxylesterase 0.0041 0.0371 0.1007
Schistosoma mansoni carbonic anhydrase-related 0.0025 0.0195 0.0195
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0098 0.0994 0.5019
Toxoplasma gondii hypothetical protein 0.0025 0.0195 0.0985
Mycobacterium leprae putative cytochrome p450 0.0017 0.0107 0.0511
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0367 0.3915 0.6664
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0017 0.0107 0.0384
Echinococcus multilocularis survival motor neuron protein 1 0.0083 0.0825 0.0825
Onchocerca volvulus 0.0217 0.2286 0.6536
Echinococcus granulosus beta LACTamase domain containing family member 0.0009 0.0018 0.0018
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.001 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.0079
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0027 0.0219 0.1105
Loa Loa (eye worm) hypothetical protein 0.0088 0.088 0.2389
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0276 0.2932 0.2932
Brugia malayi Calcitonin receptor-like protein seb-1 0.0195 0.2044 0.5788
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0017 0.0107 0.0384
Echinococcus granulosus RUN 0.0064 0.0616 0.0616
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0017 0.0107 0.0384
Loa Loa (eye worm) hypothetical protein 0.0038 0.0333 0.0904
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0009 0.002 0.002
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.001 0.003 0.0169
Loa Loa (eye worm) hypothetical protein 0.0009 0.0018 0.0049
Echinococcus granulosus mitogen activated protein kinase 3 0.0098 0.0994 0.0994
Trichomonas vaginalis D-aminoacylase, putative 0.0009 0.0018 0.0031
Loa Loa (eye worm) hypothetical protein 0.0088 0.088 0.2389
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.007 0.0686 0.0686
Schistosoma mansoni amine oxidase 0.0009 0.0021 0.0021

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 10 uM Concentration required to inhibit the human liver recombinant fructose-1,6-bisphosphatase. ChEMBL. 11140724
IC50 (binding) > 10 uM Concentration required to inhibit the human liver recombinant fructose-1,6-bisphosphatase. ChEMBL. 11140724

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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