Detailed information for compound 1125707

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 632.833 | Formula: C37H52N4O5
  • H donors: 3 H acceptors: 4 LogP: 6.77 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCCCCN1C(=O)[C@H](NC(=O)C21CCN(CC2)Cc1ccc(cc1)Oc1ccc(cc1)C(=O)NC)[C@@H](C1CCCCC1)O
  • InChi: 1S/C37H52N4O5/c1-3-4-5-6-10-23-41-35(44)32(33(42)28-11-8-7-9-12-28)39-36(45)37(41)21-24-40(25-22-37)26-27-13-17-30(18-14-27)46-31-19-15-29(16-20-31)34(43)38-2/h13-20,28,32-33,42H,3-12,21-26H2,1-2H3,(H,38,43)(H,39,45)/t32-,33-/m1/s1
  • InChiKey: PQYBXNRMHWLMRW-CZNDPXEESA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans thymidine phosphorylase 0.1206 0.3287 1
Schistosoma mansoni Smad4 0.0025 0.0017 0.0017
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0004 0.0004
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0065 0.0125 0.0212
Echinococcus granulosus glycine receptor subunit beta 0.0243 0.062 0.062
Onchocerca volvulus 0.0052 0.0089 0.016
Schistosoma mansoni amine GPCR 0.0043 0.0066 0.0066
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0041 0.006 0.0101
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0112 0.0257 0.0436
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0094 0.0205 0.0205
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0243 0.062 0.1048
Schistosoma mansoni cathepsin F (C01 family) 0.0038 0.0051 0.0051
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0518 0.1379 0.2338
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0123 0.0208
Loa Loa (eye worm) hypothetical protein 0.0131 0.0309 0.0521
Brugia malayi Nuclear hormone receptor family member nhr-14 0.014 0.0333 0.0565
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.014 0.0333 0.0333
Loa Loa (eye worm) hypothetical protein 0.0131 0.0309 0.0521
Brugia malayi chromobox protein homolog 3 0.0042 0.0062 0.0105
Echinococcus multilocularis sex peptide receptor 0.0043 0.0066 0.0065
Trichomonas vaginalis glucosylceramidase, putative 0.0544 0.1453 0.2594
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0068 0.0134 0.0421
Echinococcus granulosus cathepsin l1 0.0038 0.0051 0.0051
Echinococcus multilocularis isocitrate dehydrogenase 0.0068 0.0134 0.0133
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0017 0.003
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0111 0.0255 0.0429
Brugia malayi Calcitonin receptor-like protein seb-1 0.0518 0.1379 0.2338
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0068 0.0213
Onchocerca volvulus 0.0272 0.0699 0.1248
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Brugia malayi G-protein coupled receptor 0.0043 0.0066 0.0111
Onchocerca volvulus 0.0043 0.0066 0.0117
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.001 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0145 0.0347 0.0585
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0191 0.0476 0.0806
Schistosoma mansoni hypothetical protein 0.0043 0.0066 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0357 0.0935 0.1669
Schistosoma mansoni retinoic acid receptor RXR 0.014 0.0333 0.0333
Trypanosoma brucei CAAX amino terminal protease, putative 0.0091 0.0198 0.0335
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0052 0.0089 0.0089
Trypanosoma brucei glycosyl hydrolase-like protein 0.003 0.003 0.005
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.014 0.0333 0.0562
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0043 0.0066 0.0065
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0068 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Schistosoma mansoni survival motor neuron protein 0.0199 0.0498 0.0498
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0004 0.0003
Echinococcus multilocularis neutral alpha glucosidase AB 0.0081 0.0172 0.0171
Loa Loa (eye worm) hypothetical protein 0.0041 0.006 0.0098
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0065 0.0125 0.0212
Brugia malayi Thioredoxin reductase 0.0187 0.0463 0.0785
Brugia malayi beta-lactamase family protein 0.0111 0.0255 0.0431
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0102
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0153 0.037 0.066
Plasmodium vivax purine nucleoside phosphorylase, putative 0.0032 0.0034 0.0503
Trichomonas vaginalis glucosylceramidase, putative 0.0544 0.1453 0.2594
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.014 0.0333 0.0595
Loa Loa (eye worm) 6-phosphofructokinase 0.0118 0.0273 0.0459
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Schistosoma mansoni alpha-glucosidase 0.0316 0.0821 0.0821
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0021 0.0004 0.0003
Trichomonas vaginalis DNA topoisomerase II, putative 0.0059 0.011 0.0196
Loa Loa (eye worm) hypothetical protein 0.0978 0.2653 0.4495
Leishmania major phosphatidylinositol kinase related protein, putative 0.0021 0.0004 0.0003
Brugia malayi glutaminase DH11.1 0.0297 0.0768 0.1301
Schistosoma mansoni hypothetical protein 0.0043 0.0066 0.0066
Onchocerca volvulus 0.0281 0.0724 0.1293
Loa Loa (eye worm) fibroinase 0.0038 0.0051 0.0084
Mycobacterium leprae Probable lipase LipE 0.0111 0.0255 0.1368
Echinococcus multilocularis lipoxygenase domain containing protein 0.0063 0.0119 0.0119
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0255 0.0454
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.007 0.0139 0.0139
Schistosoma mansoni alpha-1 adrenergic receptor 0.0043 0.0066 0.0066
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0112 0.0257 0.0436
Loa Loa (eye worm) hypothetical protein 0.0111 0.0255 0.0429
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0065 0.0125 0.0376
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0408 0.1076 0.1821
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.014 0.0333 0.0333
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0043 0.0066 0.0066
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0018 0.0169
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.0348 0.0589
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0033
Entamoeba histolytica hypothetical protein 0.0023 0.001 0.0094
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0255 0.0255
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0255 0.0255
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0034 0.0009
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0474 0.1258 0.3823
Echinococcus granulosus beta LACTamase domain containing family member 0.0111 0.0255 0.0254
Loa Loa (eye worm) hypothetical protein 0.1164 0.3171 0.5372
Loa Loa (eye worm) mbt repeat family protein 0.0052 0.0089 0.0149
Brugia malayi hypothetical protein 0.0112 0.0257 0.0436
Trichomonas vaginalis glucosylceramidase, putative 0.0376 0.0988 0.1764
Schistosoma mansoni biogenic amine receptor 0.0043 0.0066 0.0066
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0068 0.0134 0.0226
Echinococcus multilocularis Polycystic kidney disease protein 0.0063 0.0119 0.0119
Echinococcus granulosus peptidase Clp S14 family 0.0108 0.0246 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0038 0.0051 0.0091
Echinococcus granulosus fmrfamide receptor 0.0043 0.0066 0.0065
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0243 0.062 0.1051
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Plasmodium falciparum JmjC domain-containing protein, putative 0.0027 0.0021 0.0067
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0084 0.015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.0348 0.0589
Echinococcus multilocularis snurportin 1 0.0304 0.0788 0.0788
Schistosoma mansoni pyruvate kinase 0.0036 0.0045 0.0045
Onchocerca volvulus 0.2041 0.5599 1
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0084 0.015
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0273 0.0487
Toxoplasma gondii ABC1 family protein 0.0111 0.0255 0.0798
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.004 0.007
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0079 0.0165 0.2474
Brugia malayi Cathepsin L-like precursor 0.0038 0.0051 0.0087
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0131 0.0309 0.0524
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0048 0.0048
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.003 0.0053
Loa Loa (eye worm) neuropeptide F receptor 0.0043 0.0066 0.0108
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0068 0.0134 0.0226
Schistosoma mansoni nuclear receptor nhr-48 0.0066 0.0129 0.0129
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0106 0.0176
Schistosoma mansoni nuclear hormone receptor 0.014 0.0333 0.0333
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.014 0.0333 0.0565
Echinococcus granulosus purine nucleoside phosphorylase 0.0153 0.037 0.0369
Loa Loa (eye worm) hypothetical protein 0.0091 0.0198 0.0332
Brugia malayi Cathepsin L-like precursor 0.0038 0.0051 0.0087
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0102 0.0227 0.0227
Brugia malayi Cytochrome P450 family protein 0.0058 0.0106 0.0179
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0038 0.0053 0.0155
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0215
Loa Loa (eye worm) hypothetical protein 0.0074 0.0151 0.0252
Brugia malayi Importin beta-1 subunit 0.0028 0.0025 0.0042
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0065 0.0125 0.039
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0118 0.0273 0.0825
Schistosoma mansoni histamine h1 receptor 0.0043 0.0066 0.0066
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.0788 0.1334
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0043 0.0066 0.0065
Echinococcus granulosus snurportin 1 0.0304 0.0788 0.0788
Brugia malayi Cathepsin L-like precursor 0.0038 0.0051 0.0087
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0043 0.0066 0.0108
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0038 0.0053 0.0155
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.006 0.0106
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0038 0.0053 0.0155
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0153 0.037 0.3595
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0165 0.0403 0.606
Trichomonas vaginalis set domain proteins, putative 0.2041 0.5599 1
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.009 0.0195 0.0195
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0112 0.0257 0.0257
Brugia malayi Cytochrome P450 family protein 0.0058 0.0106 0.0179
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0018 0.026
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0062
Brugia malayi uridine phosphorylase family protein 0.0032 0.0034 0.0057
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.003 0.0053
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0255 0.0454
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0164 0.04 0.0399
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.014 0.0333 0.0562
Loa Loa (eye worm) hypothetical protein 0.0505 0.1344 0.2275
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0059 0.0109 0.0185
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0038 0.0053 0.0155
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0279 0.072 0.072
Schistosoma mansoni 6-phosphofructokinase 0.0118 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Loa Loa (eye worm) jmjC domain-containing protein 0.0109 0.0249 0.0419
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0048 0.0142
Echinococcus granulosus tar DNA binding protein 0.0408 0.1076 0.1076
Schistosoma mansoni cpg binding protein 0.0135 0.0319 0.0319
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0163 0.0398 0.0398
Trichomonas vaginalis glutaminase, putative 0.0297 0.0768 0.1371
Brugia malayi jmjC domain containing protein 0.0027 0.0021 0.0036
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0215
Schistosoma mansoni adenoreceptor 0.0043 0.0066 0.0066
Treponema pallidum pfs protein (pfs) 0.0032 0.0034 0.0495
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0066 0.0129 0.0128
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0021 0.0004 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0083 0.014
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0118 0.0273 0.0462
Loa Loa (eye worm) hypothetical protein 0.0131 0.0309 0.0521
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.026 0.0665 0.0665
Brugia malayi Smad1 0.0025 0.0017 0.0028
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0068 0.0134 0.0134
Onchocerca volvulus 0.0043 0.0066 0.0117
Brugia malayi hypothetical protein 0.0112 0.0257 0.0436
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0025 0.0044
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0243 0.062 0.062
Schistosoma mansoni smad1 5 8 and 0.0025 0.0017 0.0017
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0112 0.0257 0.0433
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0132 0.0313 0.053
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0038 0.0053 0.0155
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0161 0.0273
Echinococcus multilocularis RUN 0.0063 0.0119 0.0119
Echinococcus multilocularis transcription factor btf3 0.0034 0.004 0.0039
Onchocerca volvulus 0.0066 0.0129 0.023
Trypanosoma brucei protein kinase, putative 0.005 0.0084 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Brugia malayi follicle stimulating hormone receptor 0.0043 0.0066 0.0111
Brugia malayi glutathione reductase 0.0187 0.0463 0.0785
Brugia malayi MH1 domain containing protein 0.0025 0.0017 0.0028
Schistosoma mansoni myelin transcription factor 1 myt1 0.0059 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.014 0.0333 0.0562
Echinococcus granulosus 6 phosphofructokinase 0.0118 0.0273 0.0272
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0068 0.0659
Leishmania major cysteine peptidase A (CPA) 0.0038 0.0051 0.0084
Toxoplasma gondii isocitrate dehydrogenase 0.0068 0.0134 0.0416
Loa Loa (eye worm) ACC-1 protein 0.0243 0.062 0.1048
Brugia malayi Isocitrate dehydrogenase 0.0068 0.0134 0.0227
Schistosoma mansoni flap endonuclease-1 0.0023 0.0011 0.0011
Plasmodium vivax importin-beta 2, putative 0.0028 0.0025 0.037
Schistosoma mansoni hypothetical protein 0.0057 0.0103 0.0103
Echinococcus granulosus chromobox protein 1 0.0075 0.0153 0.0152
Echinococcus granulosus neutral alpha glucosidase AB 0.0081 0.0172 0.0171
Mycobacterium ulcerans glutaminase 0.0297 0.0768 0.2331
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0034 0.006
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0032 0.0034 0.0057
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0243 0.062 0.1051
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0028 0.0049
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0034 0.0103
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0021 0.0004 0.0003
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0066 0.0129 0.0128
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.026 0.0665 0.0665
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0034 0.0061
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0215
Echinococcus multilocularis G-protein coupled receptor, putative 0.0043 0.0066 0.0065
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0089 0.0089
Echinococcus multilocularis nuclear receptor nhr 48 0.0066 0.0129 0.0128
Brugia malayi Cathepsin L-like precursor 0.0038 0.0051 0.0087
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0045 0.008
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.0032 0.0034 0.0326
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0038 0.0053 0.0155
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.0341 0.0889 0.5298
Loa Loa (eye worm) hypothetical protein 0.0094 0.0205 0.0345
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0038 0.0051 0.0091
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.0341 0.0889 0.2701
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0108 0.0246 0.1313
Trypanosoma cruzi target of rapamycin kinase 3 0.0021 0.0004 0.0005
Brugia malayi nuclear receptor NHR-88 0.014 0.0333 0.0565
Echinococcus granulosus dro:myosuppressin receptor 0.0043 0.0066 0.0065
Echinococcus granulosus pyruvate kinase 0.0036 0.0045 0.0045
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1304 0.3558 0.603
Brugia malayi hypothetical protein 0.0066 0.0129 0.0218
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0017 0.0016
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0426 0.1126 0.3422
Echinococcus granulosus purine nucleoside phosphorylase 0.0153 0.037 0.0369
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0021 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0126 0.0296 0.0498
Loa Loa (eye worm) hypothetical protein 0.0121 0.0282 0.0475
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0191 0.0476 0.0475
Brugia malayi neuropeptide F receptor 0.0043 0.0066 0.0111
Loa Loa (eye worm) glutaminase 2 0.0297 0.0768 0.1298
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0089 0.0089
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0227 0.0406
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.0476 0.0476
Schistosoma mansoni tar DNA-binding protein 0.0408 0.1076 0.1076
Echinococcus multilocularis chromobox protein 1 0.0075 0.0153 0.0152
Brugia malayi mbt repeat family protein 0.0052 0.0089 0.0152
Brugia malayi nuclear hormone receptor family member odr-7 0.0066 0.0129 0.0218
Trypanosoma brucei pyruvate kinase 1 0.0036 0.0045 0.0076
Leishmania major pyruvate kinase 0.0036 0.0045 0.0073
Loa Loa (eye worm) hypothetical protein 0.0111 0.0255 0.0429
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0215
Trichomonas vaginalis maltase-glucoamylase, putative 0.0081 0.0172 0.0306
Brugia malayi hypothetical protein 0.0043 0.0066 0.0111
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0034 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.0357 0.0935 0.1669
Leishmania major cathepsin L-like protease 0.0145 0.0348 0.0586
Trypanosoma cruzi major cysteine proteinase, putative 0.0114 0.0262 0.0443
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0183 0.0454 0.0769
Brugia malayi hypothetical protein 0.0043 0.0066 0.0111
Echinococcus granulosus GPCR family 2 0.0164 0.04 0.0399
Loa Loa (eye worm) hypothetical protein 0.0164 0.04 0.0674
Loa Loa (eye worm) cytochrome P450 0.0038 0.0053 0.0086
Schistosoma mansoni acetylcholine receptor-related 0.0112 0.0257 0.0257
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0164 0.04 0.0399
Loa Loa (eye worm) cysteine protease 0.0038 0.0051 0.0084
Brugia malayi Matrixin family protein 0.0505 0.1344 0.2277
Leishmania major cathepsin L-like protease 0.0038 0.0051 0.0084
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0084 0.014
Brugia malayi Nuclear hormone receptor E75 0.0066 0.0129 0.0218
Toxoplasma gondii cytochrome p450 superfamily protein 0.0038 0.0053 0.016
Echinococcus multilocularis pyruvate kinase 0.0036 0.0045 0.0045
Onchocerca volvulus 0.0111 0.0255 0.0455
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0038 0.0051 0.0091
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0243 0.062 0.1048
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0161 0.0287
Brugia malayi Cation transporter family protein 0.0243 0.062 0.1051
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0043 0.0066 0.0065
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0243 0.062 0.062
Brugia malayi Nuclear hormone receptor family member nhr-1 0.014 0.0333 0.0565
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0153 0.037 0.2081
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0043 0.0066 0.0065
Echinococcus multilocularis SAM and MBT domain containing protein 0.0052 0.0089 0.0089
Onchocerca volvulus 0.0111 0.0255 0.0455
Onchocerca volvulus Cathepsin L homolog 0.0038 0.0051 0.0092
Brugia malayi sulfakinin receptor protein 0.0043 0.0066 0.0111
Echinococcus granulosus carbonic anhydrase 0.1164 0.3171 0.317
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Loa Loa (eye worm) hypothetical protein 0.0052 0.0089 0.0149
Schistosoma mansoni opsin-like receptor 0.0043 0.0066 0.0066
Onchocerca volvulus 0.0131 0.0309 0.0552
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0059 0.011 0.0197
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0068 0.0134 0.0401
Onchocerca volvulus 0.0043 0.0066 0.0117
Loa Loa (eye worm) acetyltransferase 0.0163 0.0398 0.0672
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0004 0.0007
Echinococcus granulosus carbonic anhydrase 0.1164 0.3171 0.317
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0255 0.0454
Echinococcus granulosus somatostatin receptor 0.0043 0.0066 0.0065
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0255 0.0431
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0083 0.0247
Onchocerca volvulus 0.0043 0.0066 0.0117
Brugia malayi Cathepsin L-like precursor 0.0038 0.0051 0.0087
Echinococcus multilocularis thymidine phosphorylase 0.1206 0.3287 0.3287
Schistosoma mansoni tar DNA-binding protein 0.0408 0.1076 0.1076
Trypanosoma cruzi cysteine peptidase, putative 0.0038 0.0051 0.0087
Echinococcus multilocularis purine nucleoside phosphorylase 0.0153 0.037 0.0369
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0038 0.0053 0.0155
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0065 0.0125 0.0212
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0153 0.037 0.0627
Schistosoma mansoni nAChR subunit 0.0243 0.062 0.062
Leishmania major trypanothione reductase 0.0187 0.0463 0.0783
Leishmania major cathepsin L-like protease 0.0145 0.0348 0.0586
Schistosoma mansoni hypothetical protein 0.0032 0.0034 0.0034
Echinococcus multilocularis lamin dm0 0.0145 0.0347 0.0346
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0304 0.0787 0.0787
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0215
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.0341 0.0889 0.2701
Trypanosoma brucei pyruvate kinase 1, putative 0.0036 0.0045 0.0076
Echinococcus granulosus retinoic acid receptor rxr beta a 0.014 0.0333 0.0333
Brugia malayi cathepsin L-like precursor 0.0025 0.0017 0.0028
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0091 0.0198 0.0335
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0048 0.0151
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0057 0.0104 0.0432
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Onchocerca volvulus 0.0033 0.0037 0.0066
Toxoplasma gondii LsmAD domain-containing protein 0.0126 0.0296 0.0927
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0091 0.0198 0.0198
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0065 0.0125 0.0212
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0004 0.0003
Leishmania major cytochrome p450-like protein 0.0038 0.0053 0.0086
Echinococcus multilocularis orexin receptor type 2 0.0043 0.0066 0.0065
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0243 0.062 0.062
Echinococcus granulosus lipoxygenase domain containing protein 0.0063 0.0119 0.0119
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0083 0.0247
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0074 0.0151 0.0252
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0032 0.0034 0.0326
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0617 0.1656 0.2805
Loa Loa (eye worm) G-protein coupled receptor 0.0043 0.0066 0.0108
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0074 0.0151 0.0151
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0027 0.0021 0.0062
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0021 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Brugia malayi Probable DNA topoisomerase II 0.0059 0.011 0.0186
Mycobacterium tuberculosis Conserved protein 0.0111 0.0255 0.0769
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0083 0.0247
Echinococcus granulosus glycine receptor subunit alpha 1 0.0243 0.062 0.062
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0066 0.0129 0.0128
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0243 0.062 0.062
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0048 0.0142
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Toxoplasma gondii histone lysine methyltransferase SET1 0.0255 0.0651 0.205
Brugia malayi Cathepsin L-like precursor 0.0025 0.0017 0.0028
Entamoeba histolytica hypothetical protein 0.0079 0.0165 0.1605
Brugia malayi phosphofructokinase 0.0118 0.0273 0.0462
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0032 0.0034 0.0057
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0041 0.006 0.0101
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0065 0.0125 0.0212
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0065 0.0125 0.0394
Trichomonas vaginalis glucosylceramidase, putative 0.0357 0.0935 0.1669
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0034 0.0042 0.0041
Brugia malayi Papain family cysteine protease containing protein 0.002 0 0.0001
Schistosoma mansoni jumonji domain containing protein 0.0027 0.0021 0.0021
Echinococcus multilocularis fmrfamide receptor 0.0043 0.0066 0.0065
Echinococcus granulosus lamin dm0 0.0145 0.0347 0.0346
Toxoplasma gondii hypothetical protein 0.1164 0.3171 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0017 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Echinococcus granulosus cytoplasmic intermediate filament protein 0.007 0.0139 0.0139
Echinococcus granulosus tm gpcr rhodopsin 0.0043 0.0066 0.0065
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0027 0.0021 0.0062
Echinococcus multilocularis JmjC domain containing protein 4 0.0027 0.0021 0.0021
Leishmania major cathepsin L-like protease 0.0038 0.0051 0.0084
Brugia malayi G protein-coupled receptor 0.0043 0.0066 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0038 0.0053 0.0155
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0002 0.0002
Brugia malayi serine/threonine-protein kinase plk-2 0.0102 0.0227 0.0385
Schistosoma mansoni neuropeptide receptor 0.0043 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0215
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0038 0.0051 0.0084
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0081 0.0172 0.1671
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0066 0.0066
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0068 0.0134 0.0226
Schistosoma mansoni lamin 0.0145 0.0347 0.0347
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0038 0.0053 0.0155
Loa Loa (eye worm) RNA binding protein 0.0408 0.1076 0.1821
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0191 0.0476 0.0475
Schistosoma mansoni jumonji/arid domain-containing protein 0.0109 0.0249 0.0249
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0059 0.011 0.0186
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.0348 0.0589
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0032 0.0034 0.0312
Echinococcus granulosus purine nucleoside phosphorylase 0.0153 0.037 0.0369
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0053 0.0089
Loa Loa (eye worm) hypothetical protein 0.014 0.0333 0.0562
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.0348 0.0589
Brugia malayi GnHR receptor homolog 0.0043 0.0066 0.0111
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0004 0.0022
Loa Loa (eye worm) hypothetical protein 0.0111 0.0255 0.0429
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Onchocerca volvulus 0.0043 0.0066 0.0117
Brugia malayi hypothetical protein 0.0081 0.0172 0.0291
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0058 0.0106 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Echinococcus multilocularis nAChR subunit 0.0243 0.062 0.062
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0057 0.0104 0.1575
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0187 0.0463 0.1405
Schistosoma mansoni nAChR subunit 0.0243 0.062 0.062
Echinococcus granulosus nAChR subunit 0.0131 0.0309 0.0309
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0243 0.062 0.062
Mycobacterium ulcerans hypothetical protein 0.0111 0.0255 0.0769
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0273 0.0487
Brugia malayi hypothetical protein 0.0063 0.0119 0.0202
Trichomonas vaginalis alpha-glucosidase, putative 0.0081 0.0172 0.0306
Plasmodium falciparum carbonic anhydrase 0.1164 0.3171 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0081 0.0172 0.0288
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.0032 0.0034 0.0057
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0065 0.0125 0.1912
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.0048 0.0237
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0118 0.0273 0.0462
Echinococcus multilocularis carbonic anhydrase II 0.215 0.5901 0.59
Echinococcus multilocularis lipoxygenase domain containing protein 0.0063 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0137
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0023 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.003 0.0053
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0083 0.0806
Schistosoma mansoni nAChR subunit 0.0243 0.062 0.062
Brugia malayi nuclear hormone receptor 0.0066 0.0129 0.0218
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0153 0.0256
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.0273 0.2658
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0017 0.0016
Onchocerca volvulus Cathepsin L homolog 0.0038 0.0051 0.0092
Brugia malayi hypothetical protein 0.0043 0.0066 0.0111
Plasmodium vivax SET domain protein, putative 0.026 0.0665 1
Echinococcus granulosus tm gpcr rhodopsin 0.0043 0.0066 0.0065
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.026 0.0665 0.2093
Loa Loa (eye worm) phosphofructokinase 0.0118 0.0273 0.0459
Onchocerca volvulus 0.0505 0.1344 0.24
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0065 0.0125 0.0212
Echinococcus multilocularis g protein coupled receptor 0.0043 0.0066 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Brugia malayi hypothetical protein 0.0074 0.0151 0.0255
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0165 0.0403 0.1222
Brugia malayi ecdysone receptor 0.0066 0.0129 0.0218
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0161 0.027
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0052 0.0089 0.016
Loa Loa (eye worm) hypothetical protein 0.0067 0.0132 0.0221
Plasmodium falciparum ataxin-2 like protein, putative 0.0126 0.0296 0.0931
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0034 0.0103
Leishmania major cathepsin L-like protease 0.0038 0.0051 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Leishmania major hypothetical protein, conserved 0.0027 0.0021 0.0033
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0038 0.0053 0.0155
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0191 0.0476 0.0475
Loa Loa (eye worm) thioredoxin reductase 0.0187 0.0463 0.0783
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0079 0.014
Echinococcus granulosus lysine specific demethylase 5A 0.0109 0.0249 0.0249
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0243 0.062 0.1048
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0053 0.0052
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.0032 0.0034 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.014 0.0333 0.0562
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0068 0.0134 0.2006
Loa Loa (eye worm) hypothetical protein 0.0131 0.0309 0.0521
Mycobacterium tuberculosis Conserved protein 0.0111 0.0255 0.0769
Echinococcus multilocularis purine nucleoside phosphorylase 0.0121 0.0282 0.0282
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0272 0.0699 0.0699
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0066 0.0129 0.0128
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0079 0.0165 0.0496
Mycobacterium ulcerans DNA gyrase subunit B 0.0253 0.0648 0.1966
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0026 0.0046
Schistosoma mansoni hypothetical protein 0.0164 0.04 0.04
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0065 0.0125 0.0212
Schistosoma mansoni methylthioadenosine phosphorylase 0.0032 0.0034 0.0034
Brugia malayi hypothetical protein 0.0043 0.0066 0.0111
Schistosoma mansoni peptidase Clp (S14 family) 0.0165 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0111 0.0255 0.0429
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0079 0.0165 0.0514
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.014 0.0333 0.0562
Schistosoma mansoni zinc finger protein 0.0066 0.0129 0.0129
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0043 0.0066 0.0066
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0032 0.0034 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0038 0.0053 0.0086
Trichomonas vaginalis alpha-glucosidase, putative 0.0081 0.0172 0.0306
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0004 0.0006
Schistosoma mansoni ap endonuclease 0.002 0.0002 0.0002
Onchocerca volvulus Epoxide hydrolase 1 homolog 0.0493 0.1312 0.2344
Leishmania major alpha glucosidase II subunit, putative 0.0081 0.0172 0.0288
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0025 0.0042
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0038 0.0053 0.0155
Schistosoma mansoni transcription factor btf3 0.0034 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0017 0.0029
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0017 0.0017
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0053 0.0052
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0059 0.011 0.011
Brugia malayi TAR-binding protein 0.0408 0.1076 0.1824
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0004 0.0006
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0025 0.0042
Schistosoma mansoni retinoid-x-receptor (RXR) 0.014 0.0333 0.0333
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0038 0.0053 0.0155
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0002 0.0014
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.014 0.0333 0.0333
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0253 0.0648 0.1966
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1164 0.3171 0.5373
Schistosoma mansoni lipoxygenase 0.02 0.05 0.05
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1304 0.3558 0.603
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0079 0.0165 0.2134
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0111 0.0255 0.0769
Onchocerca volvulus 0.0112 0.0257 0.0459
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0038 0.0053 0.0155
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0043 0.0066 0.0065
Plasmodium falciparum phd finger protein, putative 0.0032 0.0034 0.0105
Brugia malayi beta-lactamase family protein 0.0111 0.0255 0.0431
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Loa Loa (eye worm) hypothetical protein 0.0032 0.0034 0.0054
Schistosoma mansoni cytochrome P450 0.0038 0.0053 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0038 0.0053 0.0155
Echinococcus multilocularis purine nucleoside phosphorylase 0.0153 0.037 0.0369
Loa Loa (eye worm) hypothetical protein 0.0041 0.006 0.0098
Schistosoma mansoni hypothetical protein 0.0304 0.0787 0.0787
Loa Loa (eye worm) glutathione reductase 0.0187 0.0463 0.0783
Chlamydia trachomatis DNA gyrase subunit B 0.0253 0.0648 1
Echinococcus multilocularis neuropeptides capa receptor 0.0043 0.0066 0.0065
Schistosoma mansoni neuropeptide F-like receptor 0.0043 0.0066 0.0066
Loa Loa (eye worm) ACC-1 protein 0.0243 0.062 0.1048
Schistosoma mansoni neuropeptide receptor 0.0043 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0153 0.037 0.112
Schistosoma mansoni hypothetical protein 0.0715 0.1928 0.1928
Brugia malayi Probable ClpP-like protease 0.0165 0.0403 0.0683
Schistosoma mansoni carbonic anhydrase 0.1164 0.3171 0.3171
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0038 0.0053 0.0155
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0038 0.0051 0.0091
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0505 0.1344 0.1344
Echinococcus granulosus serine protein kinase ATM 0.0029 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Onchocerca volvulus 0.0025 0.0017 0.003
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0084 0.015
Loa Loa (eye worm) hypothetical protein 0.0131 0.0309 0.0521
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0084 0.0143
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0165 0.0403 0.6214
Plasmodium falciparum glutathione reductase 0.0187 0.0463 0.1461
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.215 0.5901 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0021 0.0004 0.0003
Onchocerca volvulus Matrilysin homolog 0.0505 0.1344 0.24
Schistosoma mansoni uridine phosphorylase 0.0032 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0033
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0048 0.0078 0.0132
Entamoeba histolytica hypothetical protein 0.0029 0.0025 0.024
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0243 0.062 0.062
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0038 0.0053 0.0089
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0108 0.0246 0.0742
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.215 0.5901 0.5901
Schistosoma mansoni hypothetical protein 0.1164 0.3171 0.3171
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0021 0.0036
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0081 0.0172 0.0306
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0066 0.0066
Brugia malayi ORL1-like opioid receptor 0.0043 0.0066 0.0111
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0255 0.0454
Onchocerca volvulus 0.0038 0.0051 0.0092
Loa Loa (eye worm) hypothetical protein 0.0038 0.0051 0.0084
Plasmodium falciparum purine nucleoside phosphorylase 0.0032 0.0034 0.0105
Trichomonas vaginalis mercuric reductase, putative 0.0065 0.0125 0.0223
Trichomonas vaginalis glucosylceramidase, putative 0.0357 0.0935 0.1669
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0243 0.062 0.062
Loa Loa (eye worm) hypothetical protein 0.0037 0.0048 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0043 0.0066 0.0065
Onchocerca volvulus 0.0145 0.0347 0.0619
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0038 0.0051 0.0091
Loa Loa (eye worm) hypothetical protein 0.0037 0.0048 0.0079
Brugia malayi Muscleblind-like protein 0.0318 0.0827 0.1402
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0002 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.006 0.0106
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.003 0.003 0.005
Echinococcus granulosus neuropeptide Y receptor 0.0043 0.0066 0.0065
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0021 0.0004 0.0005
Onchocerca volvulus 0.0049 0.0083 0.0148
Echinococcus granulosus neuropeptides capa receptor 0.0043 0.0066 0.0065
Schistosoma mansoni biogenic amine receptor 0.0043 0.0066 0.0066
Schistosoma mansoni transcription factor LCR-F1 0.0304 0.0787 0.0787
Echinococcus multilocularis ecdysone induced protein 78C 0.014 0.0333 0.0333
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0034 0.006
Echinococcus multilocularis dro:myosuppressin receptor 0.0043 0.0066 0.0065
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0021 0.0004 0.0003
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0081 0.0172 0.0536
Schistosoma mansoni kinase 0.0052 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0243 0.062 0.1051
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0111 0.0253 0.2466
Schistosoma mansoni cpg binding protein 0.0127 0.0299 0.0299
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0025
Mycobacterium tuberculosis Probable dehydrogenase 0.0426 0.1126 0.3422
Schistosoma mansoni cathepsin F (C01 family) 0.0038 0.0051 0.0051
Brugia malayi Latrophilin receptor protein 2 0.0164 0.04 0.0677
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0034 0.006
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0043 0.0066 0.0066
Trichomonas vaginalis helicase, putative 0.0029 0.0026 0.0046
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.1206 0.3287 1
Loa Loa (eye worm) hypothetical protein 0.0505 0.1344 0.2275
Plasmodium falciparum importin beta, putative 0.0028 0.0025 0.0078
Mycobacterium ulcerans hydrolase 0.0615 0.1648 0.5011
Leishmania major carbonic anhydrase-like protein 0.215 0.5901 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.0151 0.0252
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0084 0.0143
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0106 0.0176
Echinococcus granulosus smad 0.0025 0.0017 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0544 0.1453 0.2594
Echinococcus granulosus SAM and MBT domain containing protein 0.0052 0.0089 0.0089
Echinococcus granulosus lamin 0.0145 0.0347 0.0346
Toxoplasma gondii target of rapamycin (TOR), putative 0.0021 0.0004 0.0005
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0038 0.0053 0.0155
Loa Loa (eye worm) hypothetical protein 0.0071 0.0143 0.024
Loa Loa (eye worm) cytochrome P450 family protein 0.0122 0.0284 0.0479
Schistosoma mansoni hypothetical protein 0.1813 0.4968 0.4968
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0038 0.0053 0.0155
Schistosoma mansoni nAChR subunit 0.0243 0.062 0.062
Schistosoma mansoni hypothetical protein 0.0043 0.0066 0.0066
Trichomonas vaginalis alpha-glucosidase, putative 0.0081 0.0172 0.0306
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0068 0.0134 0.0133
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0068 0.0645
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0065 0.0125 0.0212
Entamoeba histolytica cysteine proteinase, putative 0.0025 0.0017 0.0159
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0043 0.0066 0.0065
Trichomonas vaginalis alpha-glucosidase, putative 0.0081 0.0172 0.0306
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0227 0.0406
Loa Loa (eye worm) hypothetical protein 0.0165 0.0403 0.0681
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0015 0.0143
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0123 0.0123
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0004 0.0006
Echinococcus multilocularis lysosomal alpha glucosidase 0.0367 0.0962 0.0962
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0165 0.0403 0.1222
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0034 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0026 0.0046
Entamoeba histolytica hypothetical protein 0.0304 0.0787 0.768
Echinococcus granulosus g protein coupled receptor 0.0043 0.0066 0.0065
Onchocerca volvulus 0.0043 0.0066 0.0117
Plasmodium falciparum flap endonuclease 1 0.0026 0.0018 0.0055
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0696 0.1874 0.1874
Echinococcus multilocularis nAChR subunit 0.0131 0.0309 0.0309
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0026 0.0046
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0123 0.0208
Brugia malayi MH2 domain containing protein 0.0025 0.0017 0.0028
Loa Loa (eye worm) hypothetical protein 0.0131 0.0309 0.0521
Echinococcus granulosus tachykinin peptides receptor 99D 0.0043 0.0066 0.0065
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0021 0.0004 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0074 0.0151 0.0255
Schistosoma mansoni nuclear receptor 0.0066 0.0129 0.0129
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0036 0.0045 0.0131
Schistosoma mansoni carbonic anhydrase-related 0.1164 0.3171 0.3171
Echinococcus multilocularis peptidase Clp (S14 family) 0.0108 0.0246 0.0245
Mycobacterium leprae Probable pyruvate kinase PykA 0.0036 0.0045 0.0069
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0034 0.0107
Schistosoma mansoni hypothetical protein 0.0063 0.0119 0.0119
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0079 0.0165 0.0519
Plasmodium vivax DNA gyrase subunit B, putative 0.0253 0.0648 0.9739
Trypanosoma brucei carbonic anhydrase-like protein 0.215 0.5901 1
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0034 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0026 0.0046
Echinococcus granulosus neuropeptide receptor 0.0043 0.0066 0.0065
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0038 0.0053 0.0155
Onchocerca volvulus 0.0243 0.062 0.1108
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Brugia malayi MH2 domain containing protein 0.0025 0.0017 0.0028
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0034 0.006
Plasmodium falciparum DNA gyrase subunit B 0.0253 0.0648 0.2042
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0068 0.0134 0.0226
Brugia malayi Inositol-1 0.0078 0.0161 0.0273
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0215
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0066 0.0129 0.0128
Trypanosoma cruzi polo-like protein kinase, putative 0.0102 0.0227 0.0385
Loa Loa (eye worm) hypothetical protein 0.0059 0.0109 0.0182
Schistosoma mansoni amine GPCR 0.0043 0.0066 0.0066
Echinococcus multilocularis neuropeptide receptor 0.0043 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.014 0.0333 0.0562
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0165 0.0812
Loa Loa (eye worm) hypothetical protein 0.0074 0.0151 0.0252
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0255 0.0454
Brugia malayi CAAX amino terminal protease family protein 0.0091 0.0198 0.0335
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0137
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.006 0.0106
Brugia malayi hypothetical protein 0.0066 0.0129 0.0218
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0227 0.0227
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0041 0.006 0.0059
Echinococcus granulosus nuclear receptor 2DBD gamma 0.014 0.0333 0.0333
Loa Loa (eye worm) MH2 domain-containing protein 0.0374 0.0982 0.1662
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0026 0.0046
Leishmania major importin beta-1 subunit, putative 0.0023 0.001 0.0014
Onchocerca volvulus 0.0043 0.0066 0.0117
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.0348 0.0589
Echinococcus multilocularis g protein coupled receptor 0.0043 0.0066 0.0065
Schistosoma mansoni cathepsin F (C01 family) 0.0025 0.0017 0.0017
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0165 0.0403 0.0403
Toxoplasma gondii isocitrate dehydrogenase 0.0068 0.0134 0.0416
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0243 0.062 0.062
Schistosoma mansoni methylthioadenosine phosphorylase 0.0032 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.2152 0.5905 0.5905
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0048 0.0078 0.0132
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.014 0.0333 0.0562
Brugia malayi photoreceptor-specific nuclear receptor 0.014 0.0333 0.0565
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0021 0.0004 0.0003
Schistosoma mansoni hypothetical protein 0.0354 0.0926 0.0926
Plasmodium falciparum thioredoxin reductase 0.0065 0.0125 0.0394
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0034 0.0061
Loa Loa (eye worm) steroid hormone receptor 0.014 0.0333 0.0562
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0255 0.0431
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0002 0.0003
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.003 0.003 0.005
Chlamydia trachomatis DNA gyrase subunit B 0.0166 0.0406 0.6065
Loa Loa (eye worm) hypothetical protein 0.0318 0.0827 0.1399
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.014 0.0333 0.0562
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.014 0.0333 0.0333
Brugia malayi Bromodomain containing protein 0.0036 0.0045 0.0076
Giardia lamblia PHD finger protein 15 0.0032 0.0034 0.0311
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0038 0.0053 0.0155
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Plasmodium falciparum ataxin-2 like protein, putative 0.0126 0.0296 0.0931
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0043 0.0066 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0026 0.0046
Brugia malayi intermediate filament protein 0.0145 0.0347 0.0587
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0034 0.0009
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0023 0.0023
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0059 0.0109 0.0109
Loa Loa (eye worm) MBCTL1 0.0059 0.0109 0.0182
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0059 0.0109 0.0109
Echinococcus multilocularis lysine specific demethylase 5A 0.0102 0.0229 0.0229
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0057 0.0103 0.0102
Echinococcus multilocularis g protein coupled receptor 0.0043 0.0066 0.0065
Brugia malayi hypothetical protein 0.0043 0.0066 0.0111
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0034 0.0503
Brugia malayi hypothetical protein 0.0043 0.0066 0.0111
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0165 0.0403 0.1271
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0281 0.0724 0.1227
Brugia malayi Flap endonuclease-1 0.0026 0.0018 0.003
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0048 0.0721
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0038 0.0053 0.0155
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0243 0.062 0.062
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0243 0.062 0.062
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0426 0.1126 0.3422
Echinococcus granulosus nuclear receptor nhr 48 0.0066 0.0129 0.0128
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0043 0.0066 0.0066
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.0348 0.0589
Mycobacterium leprae conserved hypothetical protein 0.0111 0.0255 0.1368
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0243 0.062 0.062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Plasmodium falciparum thioredoxin reductase 0.0187 0.0463 0.1461
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0032 0.0034 0.0312
Echinococcus granulosus jumonji domain containing 1A 0.0027 0.0021 0.0021
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0038 0.0053 0.0155
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0712 0.1917 0.583
Loa Loa (eye worm) hypothetical protein 0.009 0.0195 0.0327
Plasmodium vivax glutathione reductase, putative 0.0187 0.0463 0.6965
Brugia malayi Cathepsin L-like precursor 0.0038 0.0051 0.0087
Onchocerca volvulus 0.0715 0.1928 0.3443
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0068 0.0134 0.0133
Loa Loa (eye worm) uridine phosphorylase 0.0032 0.0034 0.0054
Schistosoma mansoni biogenic amine (5HT) receptor 0.0043 0.0066 0.0066
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.1835 0.5028 0.5027
Chlamydia trachomatis pyruvate kinase 0.0036 0.0045 0.0182
Entamoeba histolytica hypothetical protein 0.0034 0.004 0.0384
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0161 0.0287
Onchocerca volvulus Bile acid receptor homolog 0.014 0.0333 0.0595
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0032 0.0034 0.0326
Schistosoma mansoni nAChR subunit 0.0112 0.0257 0.0257
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0243 0.062 0.062
Giardia lamblia NADH oxidase lateral transfer candidate 0.0065 0.0125 0.1207
Schistosoma mansoni tar DNA-binding protein 0.0408 0.1076 0.1076
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0038 0.0053 0.0155
Loa Loa (eye worm) hypothetical protein 0.0111 0.0255 0.0429
Plasmodium falciparum LCCL domain-containing protein 0.0063 0.0119 0.0376
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0059 0.011 0.0197
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0108 0.0246 0.0742
Echinococcus multilocularis muscleblind protein 1 0.0318 0.0827 0.0827
Loa Loa (eye worm) TYRA-2 protein 0.0043 0.0066 0.0108
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0617 0.1656 0.2805
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0002 0.0005
Entamoeba histolytica DNA topoisomerase II, putative 0.0059 0.011 0.107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Echinococcus granulosus glycine receptor subunit alpha 1 0.0243 0.062 0.062
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0257 0.0436
Loa Loa (eye worm) hypothetical protein 0.0505 0.1344 0.2275
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0123 0.0205
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0004 0.0006
Entamoeba histolytica hypothetical protein 0.0304 0.0787 0.768
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0227 0.0406
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Plasmodium vivax multidomain scavenger receptor, putative 0.0063 0.0119 0.1792
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0021 0.0004 0.0003
Schistosoma mansoni biogenic amine (5HT) receptor 0.0043 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0243 0.062 0.1051
Loa Loa (eye worm) hypothetical protein 0.0063 0.0119 0.0199
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0243 0.062 0.1048
Schistosoma mansoni opsin-like receptor 0.0043 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Brugia malayi hypothetical protein 0.0112 0.0257 0.0436
Treponema pallidum uridine phosphorylase (udp) 0.0032 0.0034 0.0495
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0066 0.0129 0.0129
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0034 0.0317
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0034 0.0511
Echinococcus granulosus ecdysone induced protein 78C 0.014 0.0333 0.0333
Echinococcus multilocularis thyroid hormone receptor alpha 0.014 0.0333 0.0333
Schistosoma mansoni nAChR subunit 0.0112 0.0257 0.0257
Trichomonas vaginalis glucosylceramidase, putative 0.0357 0.0935 0.1669
Brugia malayi hypothetical protein 0.0112 0.0257 0.0436
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0043 0.0066 0.0065
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0021 0.0004 0.0005
Schistosoma mansoni ran 0.0021 0.0004 0.0004
Schistosoma mansoni alpha glucosidase 0.0081 0.0172 0.0172
Trypanosoma cruzi polo-like protein kinase, putative 0.0102 0.0227 0.0385
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0038 0.0053 0.0155
Brugia malayi hypothetical protein 0.0043 0.0066 0.0111
Loa Loa (eye worm) ctsf protein 0.0038 0.0051 0.0084
Loa Loa (eye worm) beta-lactamase 0.0111 0.0255 0.0429
Schistosoma mansoni cpg binding protein 0.0135 0.0319 0.0319
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0027 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.014 0.0333 0.0562
Echinococcus multilocularis serine protein kinase ATM 0.0029 0.0025 0.0025
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.014 0.0333 0.0333
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0066 0.0066
Leishmania major cathepsin L-like protease 0.0038 0.0051 0.0084
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0079 0.0165 0.0496
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Echinococcus multilocularis inositol monophosphatase 1 0.0078 0.0161 0.0161
Brugia malayi excitatory GABA receptor EXP-1A 0.0243 0.062 0.1051
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.0273 0.2658
Loa Loa (eye worm) ICD-1 protein 0.0034 0.004 0.0064
Onchocerca volvulus 0.0199 0.0498 0.089
Schistosoma mansoni steroid hormone receptor ad4bp 0.014 0.0333 0.0333
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0083 0.0304
Onchocerca volvulus 0.0043 0.0066 0.0117
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0043 0.0066 0.0066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Echinococcus multilocularis tumor protein p63 0.0352 0.092 0.092
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0165 0.0403 0.6017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.026 0.0665 0.0665
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Brugia malayi RE15519p 0.0043 0.0066 0.0111
Brugia malayi MTAP 0.0032 0.0034 0.0057
Echinococcus multilocularis musashi 0.0145 0.0347 0.0346
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0025
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0018 0.0027
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0165 0.0403 0.1267
Schistosoma mansoni hypothetical protein 0.009 0.0195 0.0195
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.003 0.003 0.0053
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0094 0.0205 0.0205
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0062 0.011
Leishmania major mitochondrial DNA polymerase beta 0.1304 0.3558 0.6029
Onchocerca volvulus 0.0043 0.0066 0.0117
Echinococcus multilocularis histone acetyltransferase MYST2 0.0059 0.0109 0.0109
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0243 0.062 0.062
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.0348 0.0589
Onchocerca volvulus 0.0051 0.0089 0.0158
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0038 0.0053 0.0089
Echinococcus multilocularis smad 0.0025 0.0017 0.0016
Mycobacterium ulcerans esterase/lipase LipP 0.0111 0.0255 0.0769
Echinococcus granulosus 7tm_1 domain containing protein 0.0043 0.0066 0.0065
Giardia lamblia Hypothetical protein 0.0091 0.0198 0.1917
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0021 0.0004 0.0005
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0038 0.0051 0.0051
Trypanosoma cruzi DNA topoisomerase II, putative 0.0041 0.006 0.0101
Loa Loa (eye worm) hypothetical protein 0.0067 0.0132 0.0221
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.0348 0.0589
Onchocerca volvulus 0.0112 0.0257 0.0459
Brugia malayi MH1 domain containing protein 0.0025 0.0017 0.0028
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0146 0.0352 0.0595
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0091 0.0198 0.0353
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0118 0.0273 0.4194
Toxoplasma gondii phosphorylase family protein 0.0032 0.0034 0.0101
Schistosoma mansoni hypothetical protein 0.0199 0.0498 0.0498
Brugia malayi hypothetical protein 0.0043 0.0066 0.0111
Schistosoma mansoni tar DNA-binding protein 0.0408 0.1076 0.1076
Brugia malayi neuropeptide F receptor 0.0043 0.0066 0.0111
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0123 0.0208
Brugia malayi Dopamine receptor protein 1 0.0043 0.0066 0.0111
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0065 0.0125 0.1491
Brugia malayi Nuclear hormone receptor-like 1 0.014 0.0333 0.0565
Echinococcus granulosus RUN 0.0063 0.0119 0.0119
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0247 0.0631 0.0631
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0074 0.0151 0.0151
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0083 0.0137
Brugia malayi Papain family cysteine protease containing protein 0.0038 0.0051 0.0087
Trichomonas vaginalis ran, putative 0.0021 0.0004 0.0007
Leishmania major GTP-binding protein, putative 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0273 0.0487
Entamoeba histolytica cysteine protease, putative 0.0038 0.0051 0.0499
Echinococcus granulosus Nuclear hormone receptor HR96 0.0066 0.0129 0.0128
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0106 0.0179
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0066 0.0066
Brugia malayi larval opioid receptor 0.0043 0.0066 0.0111
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0083 0.0175 0.1707
Brugia malayi Cytochrome P450 family protein 0.0122 0.0284 0.0482
Echinococcus multilocularis G protein coupled receptor 139 0.0043 0.0066 0.0065
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.007 0.0139 0.0416
Mycobacterium tuberculosis Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase 0.0032 0.0034 0.0097
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0243 0.062 0.062
Echinococcus multilocularis pyruvate kinase 0.0028 0.0024 0.0024
Brugia malayi mbt repeat family protein 0.0052 0.0089 0.0152
Leishmania major nucleoside phosphorylase-like protein 0.0032 0.0034 0.0054
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0057 0.0103 0.0102
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0038 0.0051 0.0091
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0243 0.062 0.1048
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0026 0.0046
Schistosoma mansoni coup transcription factor 0.014 0.0333 0.0333
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0183 0.0454 0.0769
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0038 0.0053 0.0155
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0165 0.0403 0.0403
Echinococcus granulosus dnaJ subfamily B 0.1813 0.4968 0.4968
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Schistosoma mansoni lipoxygenase 0.0313 0.0812 0.0812
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0043 0.0066 0.0065
Loa Loa (eye worm) hydrolase 0.0493 0.1312 0.2222
Brugia malayi Intermediate filament tail domain containing protein 0.0145 0.0347 0.0587
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0243 0.062 0.1048
Schistosoma mansoni carbonic anhydrase-related 0.1164 0.3171 0.3171
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0043 0.0066 0.0065
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0083 0.0806
Schistosoma mansoni hypothetical protein 0.0038 0.0053 0.0053
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0059 0.011 0.0186
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0243 0.062 0.062
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0038 0.0053 0.0155
Brugia malayi Cation transporter family protein 0.0243 0.062 0.1051
Brugia malayi Pre-SET motif family protein 0.026 0.0665 0.1127
Echinococcus granulosus importin subunit beta 1 0.0028 0.0025 0.0025
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3251 0.8949 0.8949
Brugia malayi Matrixin family protein 0.122 0.3325 0.5636
Giardia lamblia UPL-1 0.0032 0.0034 0.0312
Loa Loa (eye worm) inositol-1 0.0078 0.0161 0.027
Echinococcus multilocularis carbonic anhydrase 0.1164 0.3171 0.317
Brugia malayi Doublecortin family protein 0.0063 0.0119 0.0202
Brugia malayi Pyruvate kinase, muscle isozyme 0.0036 0.0045 0.0076
Onchocerca volvulus Protein ultraspiracle homolog 0.014 0.0333 0.0595
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0065 0.0125 0.0394
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0146 0.0352 0.1104
Brugia malayi putative neuropeptide receptor 0.0043 0.0066 0.0111
Echinococcus multilocularis serotonin receptor 0.0043 0.0066 0.0065
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0043 0.0066 0.0066
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0079 0.0165 0.2523
Brugia malayi Nuclear hormone receptor family member nhr-41 0.014 0.0333 0.0565
Onchocerca volvulus 0.0243 0.062 0.1108
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0083 0.0175 0.1707
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0253 0.0648 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0187 0.0465 0.0465
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0273 0.0487
Echinococcus granulosus purine nucleoside phosphorylase 0.0153 0.037 0.0369
Schistosoma mansoni hypothetical protein 0.0164 0.04 0.04
Brugia malayi Nuclear hormone receptor family member nhr-25 0.014 0.0333 0.0565
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0017 0.0016
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0051 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.003 0.003 0.0048
Loa Loa (eye worm) doublecortin family protein 0.0063 0.0119 0.0199
Echinococcus granulosus purine nucleoside phosphorylase 0.0153 0.037 0.0369
Loa Loa (eye worm) hypothetical protein 0.0142 0.0339 0.0572
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Echinococcus granulosus polycomb protein SCMH1 0.0052 0.0089 0.0089
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0083 0.014
Brugia malayi ecdysteroid receptor 0.014 0.0333 0.0565
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0172 0.029
Toxoplasma gondii FATC domain-containing protein 0.0029 0.0025 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0227 0.0406
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0025 0.0025
Echinococcus multilocularis neuropeptide receptor 0.0043 0.0066 0.0065
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.0273 0.2658
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0043 0.0066 0.0066
Echinococcus granulosus neuropeptide receptor A26 0.1026 0.2788 0.2787
Leishmania major mitochondrial DNA topoisomerase II 0.0146 0.0352 0.0593
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.215 0.5901 1
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0045 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0066 0.0066
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0131 0.0309 0.0309
Toxoplasma gondii hypothetical protein 0.021 0.0529 0.1663
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0043 0.0066 0.0066
Echinococcus multilocularis geminin 0.2152 0.5905 0.5905
Plasmodium falciparum glutathione reductase 0.0065 0.0125 0.0394
Echinococcus multilocularis peregrin 0.0036 0.0045 0.0044
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0043 0.0125
Trichomonas vaginalis maltase-glucoamylase, putative 0.003 0.003 0.0053
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.009 0.0195 0.0195
Schistosoma mansoni importin beta-1 0.0028 0.0025 0.0025
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0243 0.062 0.1051
Schistosoma mansoni neurotransmitter gated ion channel 0.0131 0.0309 0.0309
Echinococcus multilocularis cpg binding protein 0.0135 0.0319 0.0318
Loa Loa (eye worm) hypothetical protein 0.0074 0.0151 0.0252
Echinococcus multilocularis fmrfamide receptor 0.0043 0.0066 0.0065
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0034 0.006
Echinococcus granulosus lipoxygenase domain containing protein 0.0063 0.0119 0.0119
Echinococcus multilocularis phd:f box containing protein 0.0027 0.0021 0.0021
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0045 0.008
Echinococcus multilocularis 6 phosphofructokinase 0.0118 0.0273 0.0272
Mycobacterium ulcerans lipase LipD 0.0111 0.0255 0.0769
Echinococcus granulosus nuclear receptor 2DBD gamma 0.014 0.0333 0.0333
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Echinococcus granulosus g-protein coupled receptor 0.0043 0.0066 0.0065
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0084 0.015
Brugia malayi Dopamine receptor 0.0043 0.0066 0.0111
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0079 0.0165 0.0496
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0021 0.0004 0.0031
Echinococcus multilocularis neuropeptide Y receptor 0.0043 0.0066 0.0065
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0065 0.0125 0.188
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0065 0.0125 0.0209
Schistosoma mansoni smad1 5 8 and 0.0025 0.0017 0.0017
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0045 0.0076
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0086 0.0153
Leishmania major glycosyl hydrolase-like protein 0.003 0.003 0.0048
Trichomonas vaginalis inositol monophosphatase, putative 0.0078 0.0161 0.0287
Loa Loa (eye worm) matrixin family protein 0.1119 0.3046 0.5161
Echinococcus multilocularis allatostatin A receptor 0.0043 0.0066 0.0065
Mycobacterium tuberculosis Probable hydrolase 0.0111 0.0255 0.0769
Loa Loa (eye worm) hypothetical protein 0.0036 0.0045 0.0073
Schistosoma mansoni hypothetical protein 0.0319 0.0829 0.0829
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0123 0.0123
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.003 0.0053
Schistosoma mansoni thyroid hormone receptor 0.014 0.0333 0.0333
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.0032 0.0034 0.0097
Brugia malayi hypothetical protein 0.0126 0.0296 0.0501
Mycobacterium ulcerans 6-phosphofructokinase 0.0118 0.0273 0.0825
Mycobacterium ulcerans beta-lactamase 0.0111 0.0255 0.0769
Schistosoma mansoni nuclear receptor 0.0066 0.0129 0.0129
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0002 0.0001
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0015 0.0022
Loa Loa (eye worm) hypothetical protein 0.1164 0.3171 0.5372
Schistosoma mansoni glutaminase 0.0297 0.0768 0.0768
Echinococcus multilocularis pyruvate kinase 0.0036 0.0045 0.0045
Schistosoma mansoni apoptosis regulator bax 0.009 0.0195 0.0195
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0165 0.0403 0.1267
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0084 0.014
Onchocerca volvulus 0.0043 0.0066 0.0117
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0018 0.0029
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0014 0.0023
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0165 0.0279
Echinococcus multilocularis glycine receptor subunit beta 0.0243 0.062 0.062
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.014 0.0333 0.0333
Brugia malayi Matrixin family protein 0.0505 0.1344 0.2277
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0038 0.0051 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-3 0.014 0.0333 0.0565
Echinococcus granulosus survival motor neuron protein 1 0.0978 0.2653 0.2653
Loa Loa (eye worm) transcription factor SMAD2 0.0374 0.0982 0.1662
Plasmodium falciparum DNA topoisomerase 2 0.0059 0.011 0.0346
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0043 0.0066 0.0066
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0078 0.0161 0.2467
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0032 0.0034 0.0057
Schistosoma mansoni alpha-glucosidase 0.0316 0.0821 0.0821
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0167 0.041 0.0409
Brugia malayi F/Y-rich N-terminus family protein 0.0059 0.0109 0.0184
Brugia malayi Nuclear hormone receptor family member nhr-31 0.014 0.0333 0.0565
Onchocerca volvulus Serine\/threonine kinase homolog 0.0102 0.0227 0.0406
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0544 0.1453 0.2459
Brugia malayi Cation transporter family protein 0.0243 0.062 0.1051
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0243 0.062 0.062
Loa Loa (eye worm) hypothetical protein 0.026 0.0665 0.1125
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.0476 0.0476
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0313 0.0812 0.0812
Loa Loa (eye worm) isocitrate dehydrogenase 0.0068 0.0134 0.0224
Echinococcus granulosus cathepsin L cysteine proteinase 0.0038 0.0051 0.0051
Schistosoma mansoni protein phosphatase 2C 0.0027 0.0021 0.0021
Onchocerca volvulus 0.0038 0.0051 0.0092
Loa Loa (eye worm) hypothetical protein 0.014 0.0333 0.0562
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.014 0.0333 0.0565
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0068 0.0134 0.0133
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0083 0.0247
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0243 0.062 0.1051
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0038 0.0051 0.0091
Brugia malayi 6-phosphofructokinase 0.0118 0.0273 0.0462
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0091 0.0198 0.0332
Entamoeba histolytica cysteine proteinase, putative 0.0038 0.0051 0.0499
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0057 0.0104 0.0326
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0111 0.0255 0.0769
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0208 0.0522 0.0522
Brugia malayi Glycosyl hydrolases family 31 protein 0.003 0.003 0.0051
Schistosoma mansoni methylthioadenosine phosphorylase 0.0032 0.0034 0.0034
Brugia malayi Serotonin receptor 0.0043 0.0066 0.0111
Trypanosoma cruzi trypanothione reductase, putative 0.0065 0.0125 0.0212
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0043 0.0066 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Echinococcus multilocularis cysteine protease 0.0038 0.0051 0.0051
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0165 0.0403 0.6214
Loa Loa (eye worm) intermediate filament protein 0.0145 0.0347 0.0585
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0078 0.0161 0.157
Loa Loa (eye worm) hypothetical protein 0.0037 0.0048 0.0079
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.014 0.0333 0.0333
Brugia malayi RNA, U transporter 1 0.0081 0.017 0.0289
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0038 0.0053 0.0155
Leishmania major phosphatidylinositol 3-kinase, putative 0.0021 0.0004 0.0003
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0131 0.0309 0.0524
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0004 0.0057
Loa Loa (eye worm) hypothetical protein 0.0518 0.1379 0.2336
Brugia malayi hypothetical protein 0.0304 0.0787 0.1334
Trypanosoma cruzi cysteine peptidase, putative 0.0145 0.0348 0.0589
Echinococcus multilocularis L aminoadipate semialdehyde 0.0281 0.0724 0.0724
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.014 0.0333 0.0333
Echinococcus granulosus histone acetyltransferase MYST2 0.0059 0.0109 0.0109
Echinococcus granulosus biogenic amine 5HT receptor 0.0043 0.0066 0.0065
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.006 0.0106
Echinococcus multilocularis GPCR, family 2 0.0164 0.04 0.0399
Echinococcus granulosus mixed lineage leukemia protein mll 0.0041 0.006 0.0059
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0083 0.014
Loa Loa (eye worm) neuropeptide F receptor 0.0043 0.0066 0.0108
Echinococcus granulosus Smad4 0.0025 0.0017 0.0016
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.004 0.0067
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0065 0.0125 0.0212
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.004 0.0124
Loa Loa (eye worm) TAR-binding protein 0.0408 0.1076 0.1821
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0243 0.062 0.062
Echinococcus granulosus cytochrome P450 2K1 0.0038 0.0053 0.0052
Echinococcus granulosus CAAX prenyl protease 2 0.0091 0.0198 0.0198
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.003 0.003 0.029
Echinococcus granulosus JmjC domain containing protein 4 0.0027 0.0021 0.0021
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0004 0.0004
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0018 0.0031
Toxoplasma gondii Purine nucleoside phosphorylase 0.0032 0.0034 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0243 0.062 0.062
Schistosoma mansoni RAR-like nuclear receptor 0.014 0.0333 0.0333
Giardia lamblia DNA repair protein RAD52 0.039 0.1025 1
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0028 0.0049
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0243 0.062 0.1051
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0068 0.0134 0.0133
Brugia malayi RNA binding protein 0.0408 0.1076 0.1824
Schistosoma mansoni amine GPCR 0.0043 0.0066 0.0066
Echinococcus granulosus biogenic amine 5HT receptor 0.0043 0.0066 0.0065
Onchocerca volvulus Huntingtin homolog 0.0119 0.0276 0.0493
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0253 0.0648 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0025
Echinococcus granulosus tumor protein p63 0.0352 0.092 0.092
Schistosoma mansoni carbonic anhydrase-related 0.1164 0.3171 0.3171
Schistosoma mansoni opsin-like receptor 0.0043 0.0066 0.0066
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0083 0.0304
Schistosoma mansoni purine nucleoside phosphorylase 0.0153 0.037 0.037
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0227 0.0406
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0083 0.0247
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0077 0.0161 0.0269
Mycobacterium tuberculosis Conserved protein 0.0111 0.0255 0.0769
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0026 0.0046
Trypanosoma cruzi cruzipain precursor, putative 0.0145 0.0348 0.0589
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0544 0.1453 0.2462
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0191 0.0476 0.0803
Entamoeba histolytica serine/threonine protein kinase, putative 0.0102 0.0227 0.2216
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1164 0.3171 0.5373
Echinococcus granulosus FTZ F1 alpha 0.014 0.0333 0.0333
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.003 0.003 0.0053
Brugia malayi tailless protein 0.0066 0.0129 0.0218
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0043 0.0066 0.0065
Mycobacterium ulcerans pyruvate kinase 0.0036 0.0045 0.0131
Schistosoma mansoni biogenic amine receptor 0.0043 0.0066 0.0066
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0065 0.0125 0.0125
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.039 0.1025 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0038 0.0051 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-49 0.014 0.0333 0.0565
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0021 0.0033
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Loa Loa (eye worm) matrix metalloproteinase 0.0505 0.1344 0.2275
Leishmania major cytochrome p450-like protein 0.0058 0.0106 0.0176
Onchocerca volvulus 0.0243 0.062 0.1108
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0043 0.0066 0.0111
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Echinococcus multilocularis purine nucleoside phosphorylase 0.0153 0.037 0.0369
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0199 0.0498 0.0844
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0084 0.0143
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0045 0.008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.006 0.0106
Onchocerca volvulus 0.0043 0.0066 0.0117
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0032 0.0034 0.0326
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0021 0.0004 0.0004
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0243 0.062 0.062
Echinococcus granulosus neuropeptides capa receptor 0.0043 0.0066 0.0065
Echinococcus multilocularis purine nucleoside phosphorylase 0.0121 0.0282 0.0282
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0045 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0026 0.0046
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0111 0.0255 0.0769
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0153 0.037 0.066
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0048 0.0048
Onchocerca volvulus 0.0131 0.0309 0.0552
Schistosoma mansoni hypothetical protein 0.0304 0.0788 0.0788
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0191 0.0476 0.0475
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0243 0.062 0.062
Loa Loa (eye worm) hypothetical protein 0.0063 0.0119 0.0199
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0062 0.0062
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0021 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0146 0.0352 0.0595
Echinococcus granulosus purine nucleoside phosphorylase 0.0153 0.037 0.0369
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0065 0.0125 0.0376
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0079 0.0165 0.0514
Schistosoma mansoni smad1 5 8 and 0.0025 0.0017 0.0017
Onchocerca volvulus 0.0112 0.0257 0.0459
Trichomonas vaginalis esterase, putative 0.0111 0.0255 0.0454
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0043 0.0066 0.0065
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0518 0.1379 0.2336
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0281 0.0724 0.0724
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1304 0.3558 0.603
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0043 0.0066 0.0111
Brugia malayi SET domain containing protein 0.0024 0.0014 0.0023
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0079 0.0165 0.2523
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0079 0.0243
Leishmania major ATP-dependent phosphofructokinase 0.0118 0.0273 0.0459
Loa Loa (eye worm) hypothetical protein 0.0318 0.0827 0.1399
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Entamoeba histolytica hypothetical protein 0.0131 0.0309 0.3014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0066 0.0066
Schistosoma mansoni rab6-interacting 0.0063 0.0119 0.0119
Onchocerca volvulus Neuropeptide F receptor homolog 0.0043 0.0066 0.0117
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Brugia malayi beta-lactamase 0.0111 0.0255 0.0431
Onchocerca volvulus 0.0243 0.062 0.1108
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0227 0.0406
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0084 0.0084
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0161 0.0273
Brugia malayi Glycosyl hydrolases family 31 protein 0.0081 0.0172 0.0291
Echinococcus multilocularis cathepsin L cysteine protease 0.0038 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0051 0.0089 0.0147
Onchocerca volvulus 0.0038 0.0051 0.0092
Schistosoma mansoni acetylcholine receptor subunit beta 0.0112 0.0257 0.0257
Trypanosoma brucei DNA topoisomerase ii 0.0146 0.0352 0.0595
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0053 0.0086
Brugia malayi isocitrate dehydrogenase 0.0068 0.0134 0.0227
Brugia malayi hypothetical protein 0.0043 0.0066 0.0111
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0065 0.0125 0.0212
Mycobacterium leprae PROBABLE HYDROLASE 0.0615 0.1648 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0164 0.04 0.0674
Echinococcus multilocularis g-protein coupled receptor 0.0043 0.0066 0.0065
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0223 0.0565 0.0957
Onchocerca volvulus 0.0145 0.0347 0.0619
Brugia malayi putative neuropeptide receptor NPR1 0.0043 0.0066 0.0111
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0034 0.0511
Onchocerca volvulus 0.0038 0.0051 0.0092
Schistosoma mansoni nAChR subunit 0.0243 0.062 0.062
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0084 0.0084
Brugia malayi RNA recognition motif domain containing protein 0.0408 0.1076 0.1824
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.004 0.0384
Echinococcus granulosus thymidine phosphorylase 0.1206 0.3287 0.3287
Brugia malayi Nuclear hormone receptor family member nhr-25 0.014 0.0333 0.0565
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0127 0.0212
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.009 0.0195 0.033
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0043 0.0066 0.0066
Mycobacterium tuberculosis Conserved hypothetical protein 0.0687 0.1849 0.5621
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0065 0.0125 0.0376
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0426 0.1126 0.3422
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0243 0.062 0.1051
Brugia malayi Matrixin family protein 0.0505 0.1344 0.2277
Trypanosoma cruzi PAB1-binding protein , putative 0.0126 0.0296 0.05
Echinococcus multilocularis serotonin receptor 0.0043 0.0066 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0081 0.0172 0.1671
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0017 0.0029
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0084 0.014
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0034 0.006
Schistosoma mansoni neuropeptide f receptor 76f 0.0043 0.0066 0.0066
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0083 0.0247
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0043 0.0066 0.0066
Echinococcus granulosus glycine receptor subunit beta 0.0243 0.062 0.062
Brugia malayi Nuclear hormone receptor family member nhr-19 0.014 0.0333 0.0565
Echinococcus granulosus cathepsin l cysteine peptidase 0.0038 0.0051 0.0051
Schistosoma mansoni jumonji domain containing protein 0.0146 0.0351 0.0351
Onchocerca volvulus Huntingtin homolog 0.0119 0.0276 0.0493
Trypanosoma brucei uridine phosphorylase 0.0032 0.0034 0.0057
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.0032 0.0034 0.0495
Brugia malayi Papain family cysteine protease containing protein 0.002 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0281 0.0724 0.1224
Entamoeba histolytica CAAX prenyl protease family 0.0091 0.0198 0.1928
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.0348 0.0589
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0208 0.0522 0.0522
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0243 0.062 0.1051
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Echinococcus granulosus inositol monophosphatase 1 0.0078 0.0161 0.0161
Brugia malayi nuclear receptor RXR 0.0074 0.0151 0.0255
Echinococcus granulosus serotonin receptor 0.0043 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0029 0.0025 0.0025
Echinococcus granulosus methylthioadenosine phosphorylase 0.0032 0.0034 0.0033
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0065 0.0125 0.0376
Entamoeba histolytica hypothetical protein 0.0111 0.0253 0.2466
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0153 0.0272
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0066 0.0129 0.0215
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0045 0.0073
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0215
Schistosoma mansoni ran 0.0021 0.0004 0.0004
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0165 0.0403 0.2288
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.009 0.0195 0.0195
Echinococcus multilocularis dnaJ subfamily B 0.1813 0.4968 0.4968
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0017 0.0016
Brugia malayi cytoplasmic intermediate filament protein 0.0077 0.0161 0.0272
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0243 0.062 0.1051
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0084 0.0084
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0034 0.0101
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0043 0.0066 0.0066
Mycobacterium tuberculosis Probable esterase LipL 0.0111 0.0255 0.0769
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0034 0.0061
Loa Loa (eye worm) CXXC zinc finger family protein 0.0127 0.0299 0.0503
Trypanosoma cruzi cysteine peptidase, putative 0.0145 0.0348 0.0589
Onchocerca volvulus 0.0043 0.0066 0.0117
Trichomonas vaginalis glucosylceramidase, putative 0.0376 0.0988 0.1764
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0004 0.0004
Loa Loa (eye worm) CYP4Cod1 0.0058 0.0106 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Brugia malayi nuclear receptor RXR 0.0066 0.0129 0.0218
Echinococcus multilocularis neuropeptide s receptor 0.1026 0.2788 0.2787
Schistosoma mansoni intermediate filament proteins 0.0145 0.0347 0.0347
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Plasmodium vivax DNA topoisomerase II, putative 0.0059 0.011 0.165
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0021 0.0004 0.0005
Echinococcus multilocularis cysteine protease 0.0038 0.0051 0.0051
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.001 0.0016
Mycobacterium tuberculosis Probable lipase LipD 0.0111 0.0255 0.0769
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0066 0.0129 0.023
Plasmodium vivax vivapain-2 0.0038 0.0051 0.0769
Toxoplasma gondii pyruvate kinase PyK1 0.0036 0.0045 0.0136
Brugia malayi latrophilin 2 splice variant baaae 0.0354 0.0926 0.1569
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.009 0.0195 0.0195
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.014 0.0333 0.0333
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0018 0.005
Schistosoma mansoni nAChR subunit 0.0243 0.062 0.062
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0065 0.0125 0.0212
Schistosoma mansoni nuclear hormone receptor 0.0066 0.0129 0.0129
Echinococcus granulosus allatostatin A receptor 0.0043 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0112 0.0257 0.0257
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0066 0.0129 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Brugia malayi hypothetical protein 0.0978 0.2653 0.4497
Brugia malayi jmjC domain containing protein 0.0167 0.041 0.0695
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Leishmania major cathepsin L-like protease 0.0145 0.0348 0.0586
Schistosoma mansoni inositol monophosphatase 0.0078 0.0161 0.0161
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0038 0.0053 0.0155
Echinococcus granulosus peregrin 0.0036 0.0045 0.0044
Brugia malayi Serotonin receptor 0.0043 0.0066 0.0111
Echinococcus multilocularis lysosomal alpha glucosidase 0.0367 0.0962 0.0962
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.1164 0.3171 0.5372
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0172 0.029
Echinococcus granulosus glycine receptor subunit alpha 1 0.0243 0.062 0.062
Onchocerca volvulus 0.014 0.0333 0.0595
Loa Loa (eye worm) hypothetical protein 0.0037 0.0048 0.0079
Loa Loa (eye worm) nuclear receptor NHR-67 0.0066 0.0129 0.0215
Brugia malayi Glycosyl hydrolases family 31 protein 0.0367 0.0962 0.1631
Plasmodium vivax JmjC domain containing protein 0.0027 0.0021 0.0318
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0243 0.062 0.062
Brugia malayi jmjC domain containing protein 0.0027 0.0021 0.0036
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0065 0.0125 0.0209
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0043 0.0066 0.0065
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0163 0.0398 0.0398
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0112 0.0257 0.0257
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0038 0.0053 0.0155
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0145 0.0347 0.0585
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0032 0.0034 0.006
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0066 0.0129 0.0128
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0065 0.0125 0.0209
Echinococcus granulosus cathepsin l1 0.0025 0.0017 0.0016
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0034 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0083 0.0247
Loa Loa (eye worm) hypothetical protein 0.0131 0.0309 0.0521
Trichomonas vaginalis glucosylceramidase, putative 0.0357 0.0935 0.1669
Loa Loa (eye worm) acetylcholine receptor protein 0.0112 0.0257 0.0433
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Giardia lamblia DNA topoisomerase II 0.0051 0.0088 0.0842
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.003 0.003 0.0054
Toxoplasma gondii cathepsin CPL 0.0038 0.0051 0.0157
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0021 0.0004 0.0005
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0079 0.0079
Echinococcus multilocularis methylthioadenosine phosphorylase 0.0032 0.0034 0.0033
Toxoplasma gondii thioredoxin reductase 0.0187 0.0463 0.1457
Schistosoma mansoni 6-phosphofructokinase 0.0118 0.0273 0.0273
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.215 0.5901 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0161 0.0273
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.001 0.0017
Echinococcus multilocularis neuropeptides capa receptor 0.0043 0.0066 0.0065
Onchocerca volvulus 0.0043 0.0066 0.0117
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0043 0.0066 0.0108
Echinococcus granulosus orexin receptor type 2 0.0043 0.0066 0.0065
Echinococcus granulosus cpg binding protein 0.0135 0.0319 0.0318
Loa Loa (eye worm) hypothetical protein 0.007 0.0139 0.0233
Echinococcus granulosus peptide allatostatin:somatostatin 0.0043 0.0066 0.0065
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0043 0.0066 0.0065
Plasmodium falciparum cysteine proteinase falcipain 3 0.0038 0.0051 0.0161
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0066 0.0129 0.023
Schistosoma mansoni neuropeptide receptor 0.0043 0.0066 0.0066
Plasmodium vivax thioredoxin reductase, putative 0.0187 0.0463 0.6965
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0165 0.0403 0.6017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0043 0.0125
Brugia malayi hydrolase, alpha/beta fold family protein 0.0245 0.0624 0.1058
Entamoeba histolytica Ran family GTPase 0.0021 0.0004 0.0037
Plasmodium vivax ataxin-2 like protein, putative 0.0126 0.0296 0.4441
Schistosoma mansoni hypothetical protein 0.0164 0.04 0.04
Mycobacterium leprae Conserved hypothetical protein 0.0038 0.0053 0.0117
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0066 0.0066
Brugia malayi Cytochrome P450 family protein 0.0038 0.0053 0.0089
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0038 0.0051 0.0161
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0304 0.0787 0.0787
Brugia malayi Trypsin family protein 0.0094 0.0205 0.0348
Onchocerca volvulus Glucosylceramidase homolog 0.0357 0.0935 0.1669
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0043 0.0125
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Brugia malayi hypothetical protein 0.0043 0.0066 0.0111
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0038 0.0053 0.0155
Trypanosoma cruzi trypanothione reductase, putative 0.0187 0.0463 0.0785
Schistosoma mansoni neuropeptide F-like receptor 0.0043 0.0066 0.0066
Toxoplasma gondii NADPH-glutathione reductase 0.0065 0.0125 0.039
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0043 0.0066 0.0111
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Leishmania major hypothetical protein, conserved 0.0111 0.0255 0.0429
Brugia malayi MH2 domain containing protein 0.0374 0.0982 0.1665
Schistosoma mansoni chromobox protein 0.0075 0.0153 0.0153
Echinococcus multilocularis lamin 0.0145 0.0347 0.0346
Brugia malayi Cathepsin L-like cysteine proteinase 0.0025 0.0017 0.0028
Leishmania major hypothetical protein, conserved 0.0126 0.0296 0.0498
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.014 0.0333 0.0562
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0018 0.0027
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0034 0.0107
Onchocerca volvulus Alhambra homolog 0.0032 0.0034 0.006
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0038 0.0053 0.0155
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0164 0.04 0.0399
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0046 0.0081
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0111 0.0255 0.0769
Echinococcus multilocularis CAAX prenyl protease 2 0.0091 0.0198 0.0198
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0164 0.04 0.0677
Echinococcus multilocularis polycomb protein SCMH1 0.0052 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Onchocerca volvulus 0.0063 0.0119 0.0213
Loa Loa (eye worm) hypothetical protein 0.0131 0.0309 0.0521
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0227 0.0406
Giardia lamblia Kinase, PLK 0.0102 0.0227 0.2205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Loa Loa (eye worm) hypothetical protein 0.0025 0.0014 0.0021
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0131 0.0309 0.0309
Echinococcus granulosus thyroid hormone receptor alpha 0.0066 0.0129 0.0128
Echinococcus granulosus neuropeptide receptor 0.0043 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.014 0.0333 0.0333
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0038 0.0053 0.0155
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0004 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0062 0.0062
Brugia malayi Melatonin receptor type 1A 0.0043 0.0066 0.0111
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0074 0.0151 0.015
Echinococcus granulosus g protein coupled receptor 0.0043 0.0066 0.0065
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0123 0.0208
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0074 0.0151 0.015
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0027 0.0021 0.0036
Loa Loa (eye worm) hypothetical protein 0.014 0.0333 0.0562
Echinococcus multilocularis FTZ F1 alpha 0.014 0.0333 0.0333
Echinococcus granulosus uridine phosphorylase 1 0.0032 0.0034 0.0033
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0084 0.0807
Schistosoma mansoni neurotransmitter gated ion channel 0.0112 0.0257 0.0257
Brugia malayi Dopamine receptor protein 2 0.0043 0.0066 0.0111
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0068 0.0134 0.0133
Echinococcus granulosus Nuclear hormone receptor HR96 0.0066 0.0129 0.0128
Echinococcus multilocularis lysine specific demethylase 6a 0.0027 0.0021 0.0021
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0118 0.0273 0.148
Brugia malayi 6-phosphofructokinase 0.0118 0.0273 0.0462
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0049 0.0081 0.0081
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0164 0.04 0.0399
Mycobacterium tuberculosis Hypothetical protein 0.0032 0.0034 0.0097
Brugia malayi jmjC domain containing protein 0.0027 0.0021 0.0036
Echinococcus granulosus neuropeptide s receptor 0.1026 0.2788 0.2787
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0018 0.0155
Trichomonas vaginalis glucosylceramidase, putative 0.0544 0.1453 0.2594
Trichomonas vaginalis glucosylceramidase, putative 0.0544 0.1453 0.2594
Echinococcus multilocularis cathepsin L cysteine protease 0.0038 0.0051 0.0051
Brugia malayi Nuclear hormone receptor E75 0.0066 0.0129 0.0218
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0043 0.0066 0.0108
Onchocerca volvulus 0.0043 0.0066 0.0117
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0068 0.0068
Schistosoma mansoni ap endonuclease 0.002 0.0002 0.0002
Brugia malayi hypothetical protein 0.0112 0.0257 0.0436
Brugia malayi orphan nuclear receptor NR2E1 0.0066 0.0129 0.0218
Loa Loa (eye worm) hypothetical protein 0.0131 0.0309 0.0521
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.004 0.007
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0025 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Echinococcus multilocularis purine nucleoside phosphorylase 0.0153 0.037 0.0369
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0087 0.0188 0.0953
Leishmania major DNA topoisomerase ii 0.0041 0.006 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Echinococcus granulosus Polycystic kidney disease protein 0.0063 0.0119 0.0119
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0106 0.0179
Treponema pallidum NADH oxidase 0.0065 0.0125 0.1912
Echinococcus granulosus hypothetical protein 0.0043 0.0066 0.0065
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0065 0.0125 0.0125
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0153 0.037 0.112
Leishmania major methylthioadenosine phosphorylase, putative 0.0032 0.0034 0.0054
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.014 0.0333 0.0333
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0243 0.062 0.1051
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.215 0.5901 0.5901
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0243 0.062 0.062
Brugia malayi beta-NAC-like protein 0.0034 0.004 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0038 0.0051 0.0091
Schistosoma mansoni nuclear hormone receptor 0.0066 0.0129 0.0129
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0038 0.0053 0.0155
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0021 0.0004 0.0031
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0043 0.0125
Plasmodium falciparum pyruvate kinase 0.0036 0.0045 0.0141
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0084 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-40 0.014 0.0333 0.0565
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0257 0.0436
Echinococcus multilocularis microtubule associated protein 2 0.363 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0066 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0112 0.0257 0.0433
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0426 0.1126 0.6766
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0065 0.0125 0.0212
Brugia malayi conserved hypotetical protein 0.0066 0.0129 0.0218
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0065 0.0125 0.0125
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0065 0.0125 0.0209
Schistosoma mansoni chromobox protein 0.0075 0.0153 0.0153
Echinococcus granulosus G protein coupled receptor 139 0.0043 0.0066 0.0065
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0083 0.0247
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0032 0.0034 0.0326
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0084 0.0143
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0038 0.0053 0.0155
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0102 0.0227 0.0382
Loa Loa (eye worm) 6-phosphofructokinase 0.0118 0.0273 0.0459
Onchocerca volvulus 0.0212 0.0534 0.0953
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0215
Leishmania major phosphopantetheinyl transferase-like protein 0.0079 0.0165 0.0276
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0045 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-19 0.014 0.0333 0.0565
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0091 0.0198 0.0335
Schistosoma mansoni lamin 0.0145 0.0347 0.0347
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.014 0.0333 0.0562
Brugia malayi jmjC domain containing protein 0.0027 0.0021 0.0036
Schistosoma mansoni nAChR subunit 0.0243 0.062 0.062
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Echinococcus multilocularis jumonji domain containing 1A 0.0027 0.0021 0.0021
Entamoeba histolytica hypothetical protein 0.0032 0.0034 0.0326
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0083 0.0806
Brugia malayi Hemopexin family protein 0.0715 0.1928 0.3267
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.1164 0.3171 0.5373
Brugia malayi cytochrome P450 0.0038 0.0053 0.0089
Echinococcus multilocularis neuropeptide Y receptor 0.0043 0.0066 0.0065
Echinococcus granulosus histone lysine methyltransferase setb 0.026 0.0665 0.0665
Trypanosoma brucei glucosidase, putative 0.0081 0.0172 0.029
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0243 0.062 0.062
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.009 0.0195 0.0195
Onchocerca volvulus Matrix metalloproteinase homolog 0.1119 0.3046 0.544
Mycobacterium tuberculosis Conserved hypothetical protein 0.0032 0.0034 0.0097
Entamoeba histolytica cysteine proteinase, putative 0.0038 0.0051 0.0499
Schistosoma mansoni uridine phosphorylase 0.0032 0.0034 0.0034
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0034 0.0033
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0183 0.0454 0.0769
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0066 0.0129 0.0218
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.007 0.0139 0.065
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0243 0.062 0.1051
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0034 0.0061
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0066 0.0129 0.0128
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0038 0.0053 0.0155
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0038 0.0051 0.0161
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0474 0.1258 0.7582
Entamoeba histolytica hypothetical protein 0.0304 0.0787 0.768
Schistosoma mansoni hypothetical protein 0.0043 0.0066 0.0066
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.014 0.0333 0.0333
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.026 0.0665 0.0665
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.1164 0.3171 0.5373
Schistosoma mansoni polycystin 1-related 0.0063 0.0119 0.0119
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.0476 0.0476
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0041 0.006 0.0059
Brugia malayi hypothetical protein 0.0063 0.0119 0.0202
Toxoplasma gondii phosphorylase family protein 0.0032 0.0034 0.0101
Echinococcus multilocularis tar DNA binding protein 0.0408 0.1076 0.1076
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0023 0.004
Schistosoma mansoni smad 0.0025 0.0017 0.0017
Loa Loa (eye worm) carbonic anhydrase 3 0.215 0.5901 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0065 0.0125 0.1912
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Toxoplasma gondii NAC domain-containing protein 0.0034 0.004 0.012
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0068 0.0134 0.0224
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Echinococcus multilocularis muscleblind protein 0.0318 0.0827 0.0827
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.004 0.0592
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0045 0.0073
Mycobacterium ulcerans hypothetical protein 0.0687 0.1849 0.5621
Schistosoma mansoni DNA topoisomerase II 0.0059 0.011 0.011
Brugia malayi Steroid receptor seven-up type 2 0.014 0.0333 0.0565
Brugia malayi hypothetical protein 0.0119 0.0276 0.0468
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0034 0.006
Giardia lamblia GTOR 0.0021 0.0004 0.0017
Mycobacterium tuberculosis Probable oxidoreductase 0.0474 0.1258 0.3823
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0034 0.0061
Loa Loa (eye worm) Smad1 0.0025 0.0017 0.0025
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0034 0.0061
Echinococcus multilocularis glycine receptor subunit beta 0.0243 0.062 0.062
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0215
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0243 0.062 0.1051
Brugia malayi G-protein coupled receptor 0.0043 0.0066 0.0111
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0123 0.0205
Loa Loa (eye worm) TOPoisomerase family member 0.0059 0.011 0.0183
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0038 0.0053 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0062 0.011
Echinococcus granulosus purine nucleoside phosphorylase 0.0153 0.037 0.0369
Mycobacterium tuberculosis Probable lipase LipE 0.0111 0.0255 0.0769
Echinococcus granulosus pyruvate kinase 0.0036 0.0045 0.0045
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0079 0.0243
Brugia malayi steroid hormone receptor 0.014 0.0333 0.0565
Loa Loa (eye worm) hypothetical protein 0.0083 0.0175 0.0294
Schistosoma mansoni microtubule-associated protein tau 0.363 1 1
Loa Loa (eye worm) G-protein coupled receptor 0.0043 0.0066 0.0108
Toxoplasma gondii DNA topoisomerase 2, putative 0.0059 0.011 0.0342
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0022
Brugia malayi acetyltransferase, GNAT family protein 0.0163 0.0398 0.0674
Onchocerca volvulus 0.0094 0.0205 0.0366
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0043 0.0066 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0112 0.0257 0.0436
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0167 0.041 0.0409
Mycobacterium leprae putative cytochrome p450 0.0038 0.0053 0.0117
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0131 0.0309 0.0524
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0002 0.0002
Echinococcus granulosus nAChR subunit 0.0243 0.062 0.062
Leishmania major basic transcription factor 3a, putative 0.0034 0.004 0.0064
Trichomonas vaginalis glutathione reductase, putative 0.0065 0.0125 0.0223
Loa Loa (eye worm) apoptosis regulator protein 0.009 0.0195 0.0327
Schistosoma mansoni growth hormone secretagogue receptor 0.0043 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.014 0.0333 0.0562
Mycobacterium ulcerans hypothetical protein 0.0049 0.0083 0.0247
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0057 0.0104 0.1553
Trichomonas vaginalis importin beta-1, putative 0.0023 0.001 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0043 0.0066 0.0066
Trichomonas vaginalis sucrase-isomaltase, putative 0.0081 0.0172 0.0306
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0038 0.0053 0.0155
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1793 0.4914 0.8327
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0112 0.0257 0.0257
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0021 0.0004 0.0004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0049 0.0081 0.0081
Echinococcus multilocularis 0.0038 0.0053 0.0052
Brugia malayi CXXC zinc finger family protein 0.0127 0.0299 0.0506
Schistosoma mansoni tar DNA-binding protein 0.0408 0.1076 0.1076
Plasmodium vivax hypothetical protein, conserved 0.0111 0.0255 0.3825
Schistosoma mansoni loxhd1 0.0063 0.0119 0.0119
Echinococcus granulosus intermediate filament protein 0.0145 0.0347 0.0346
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0004 0.0012
Loa Loa (eye worm) histone methyltransferase 0.0049 0.0081 0.0135
Loa Loa (eye worm) glutaminase 0.0297 0.0768 0.1298
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0038 0.0051 0.0091
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0079 0.1182
Schistosoma mansoni Tr4/Tr2 (homologue) 0.014 0.0333 0.0333
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0243 0.062 0.1051
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0062 0.011
Loa Loa (eye worm) LGC-31 protein 0.0243 0.062 0.1048
Schistosoma mansoni amine GPCR 0.0043 0.0066 0.0066
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.006 0.0106
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0071 0.0126
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0123 0.1196
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.004 0.007
Plasmodium vivax vivapain-2 0.0038 0.0051 0.0769
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0059
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0131 0.0309 0.0524
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0034 0.0101
Schistosoma mansoni rab6-interacting 0.0063 0.0119 0.0119
Echinococcus granulosus neuropeptide Y receptor 0.0043 0.0066 0.0065
Trichomonas vaginalis alpha-glucosidase, putative 0.0081 0.0172 0.0306
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0043 0.0066 0.0065
Brugia malayi Putative carbonic anhydrase 5 precursor 0.215 0.5901 1
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Brugia malayi nuclear receptor NHR-88 0.0066 0.0129 0.0218
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0084 0.0143
Echinococcus granulosus chromobox protein 1 0.0075 0.0153 0.0152
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0043 0.0066 0.0108
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0102 0.0227 0.0227
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0243 0.062 0.1051
Echinococcus granulosus histone acetyltransferase KAT2B 0.0159 0.0385 0.0385
Loa Loa (eye worm) hypothetical protein 0.0119 0.0276 0.0465
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0043 0.0066 0.0111
Leishmania major cytochrome p450-like protein 0.0038 0.0053 0.0086
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0034 0.0331
Brugia malayi Pyruvate kinase, M2 isozyme 0.0036 0.0045 0.0076
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0617 0.1656 0.2804
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.0348 0.0589
Loa Loa (eye worm) hypothetical protein 0.0111 0.0255 0.0429
Echinococcus multilocularis uridine phosphorylase 1 0.0032 0.0034 0.0033
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0002 0.0022
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0065 0.0125 0.188
Onchocerca volvulus 0.0038 0.0051 0.0092
Echinococcus granulosus phd:f box containing protein 0.0027 0.0021 0.0021
Brugia malayi Heterochromatin protein 1 0.0075 0.0153 0.0259
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Onchocerca volvulus Putative nachr subunit 0.0243 0.062 0.1108
Onchocerca volvulus 0.0043 0.0066 0.0117
Echinococcus granulosus purine nucleoside phosphorylase 0.0153 0.037 0.0369
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0078 0.0161 0.0503
Schistosoma mansoni hypothetical protein 0.0164 0.04 0.04
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0215
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0039
Brugia malayi nuclear receptor NHR-67 0.0066 0.0129 0.0218
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0059 0.011 0.0197
Onchocerca volvulus 0.0038 0.0051 0.0092
Schistosoma mansoni neuropeptide receptor 0.0043 0.0066 0.0066
Echinococcus granulosus muscleblind protein 0.0318 0.0827 0.0827
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.014 0.0333 0.0333
Loa Loa (eye worm) hypothetical protein 0.0037 0.0048 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0051 0.0091
Onchocerca volvulus Matrilysin homolog 0.1119 0.3046 0.544
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0086 0.0153
Loa Loa (eye worm) hypothetical protein 0.1164 0.3171 0.5372
Schistosoma mansoni pyruvate kinase 0.0036 0.0045 0.0045
Echinococcus granulosus lysosomal alpha glucosidase 0.0367 0.0962 0.0962
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0038 0.0053 0.0155
Echinococcus multilocularis chromobox protein 1 0.0075 0.0153 0.0152
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1164 0.3171 0.5373
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0615 0.1648 0.2793
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0102 0.0227 0.0382
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0084 0.0261
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0038 0.0053 0.0155
Onchocerca volvulus 0.0243 0.062 0.1108
Mycobacterium tuberculosis Probable reductase 0.0426 0.1126 0.3422
Echinococcus multilocularis somatostatin receptor 0.0043 0.0066 0.0065
Onchocerca volvulus 0.0087 0.0188 0.0336
Brugia malayi G protein-coupled receptor F59B2.13 0.0043 0.0066 0.0111
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0004 0.0006
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0034 0.0054
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0313 0.0812 0.0812
Brugia malayi Tachykinin-like peptides receptor 99D 0.0043 0.0066 0.0111
Loa Loa (eye worm) hypothetical protein 0.0615 0.1648 0.2791
Trichomonas vaginalis glucosylceramidase, putative 0.0357 0.0935 0.1669
Echinococcus granulosus 7TM GPCR rhodopsin 0.0043 0.0066 0.0065
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0021 0.0033
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.215 0.5901 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.006 0.0106
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0018 0.0017
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0153 0.0272
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0243 0.062 0.062
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0038 0.0053 0.0089
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0615 0.1648 0.5011
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0071 0.0126
Brugia malayi AKH receptor 0.0043 0.0066 0.0111
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0021 0.0036
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Echinococcus granulosus alpha 1A adrenergic receptor 0.0043 0.0066 0.0065
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0071 0.0126
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Echinococcus multilocularis beta LACTamase domain containing family member 0.0111 0.0255 0.0254
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0091 0.0198 0.0198
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0081 0.0172 0.0306
Onchocerca volvulus 0.0243 0.062 0.1108
Echinococcus granulosus lysine specific demethylase 6a 0.0027 0.0021 0.0021
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0029 0.0025 0.0042
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0474 0.1258 0.3823
Loa Loa (eye worm) hypothetical protein 0.0094 0.0205 0.0345
Trichomonas vaginalis alpha-glucosidase, putative 0.003 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0119 0.0276 0.0465
Entamoeba histolytica hypothetical protein 0.0304 0.0787 0.768
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0043 0.0066 0.0108
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0059 0.011 0.011
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0038 0.0051 0.0084
Loa Loa (eye worm) hypothetical protein 0.0354 0.0926 0.1567
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0034 0.0501
Loa Loa (eye worm) GABA receptor subunit 0.0131 0.0309 0.0521
Brugia malayi PHD-finger family protein 0.0032 0.0034 0.0057
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0215
Echinococcus granulosus tm gpcr rhodopsin 0.0043 0.0066 0.0065
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0123 0.0123
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0034 0.0033
Echinococcus granulosus transcription factor btf3 0.0034 0.004 0.0039
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0021 0.0033
Schistosoma mansoni amine GPCR 0.0043 0.0066 0.0066
Loa Loa (eye worm) nuclear hormone receptor 0.0066 0.0129 0.0215
Loa Loa (eye worm) hypothetical protein 0.0112 0.0257 0.0433
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0243 0.062 0.1051
Toxoplasma gondii hypothetical protein 0.0057 0.0104 0.0321
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0002 0.0001
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0083 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Brugia malayi Pre-SET motif family protein 0.1793 0.4914 0.8327
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0083 0.0137
Brugia malayi jmjC domain containing protein 0.0109 0.0249 0.0422
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0078 0.0161 0.0485
Echinococcus multilocularis survival motor neuron protein 1 0.0978 0.2653 0.2653
Schistosoma mansoni purine nucleoside phosphorylase 0.0153 0.037 0.037
Brugia malayi hypothetical protein 0.0074 0.0151 0.0255
Echinococcus granulosus sex peptide receptor 0.0043 0.0066 0.0065
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0074 0.0151 0.0252
Schistosoma mansoni phosphatidylserine receptor 0.0027 0.0021 0.0021
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.004 0.0067
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0112 0.0257 0.0257
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0043 0.0066 0.0065
Brugia malayi Cathepsin L-like precursor 0.0025 0.0017 0.0028
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0029 0.0025 0.0042
Echinococcus granulosus carbonic anhydrase II 0.215 0.5901 0.59
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0038 0.0053 0.0155
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0043 0.0066 0.0065
Brugia malayi nuclear hormone receptor family member nhr-6 0.0066 0.0129 0.0218
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.026 0.0665 0.0665
Echinococcus multilocularis neuropeptide FF receptor 2 0.0043 0.0066 0.0065
Schistosoma mansoni hypothetical protein 0.009 0.0195 0.0195
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0029 0.0025 0.0042
Echinococcus granulosus neuropeptide FF receptor 2 0.0043 0.0066 0.0065
Schistosoma mansoni myosin xvIII 0.0043 0.0066 0.0066
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0045 0.008
Schistosoma mansoni jumonji/arid domain-containing protein 0.0109 0.0249 0.0249
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0367 0.0962 0.1628
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0083 0.0247
Schistosoma mansoni phd/f-box containing protein 0.0027 0.0021 0.0021
Onchocerca volvulus 0.0038 0.0051 0.0092
Echinococcus granulosus L aminoadipate semialdehyde 0.0281 0.0724 0.0724
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0038 0.0051 0.0091
Onchocerca volvulus 0.0043 0.0066 0.0117
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0065 0.0125 0.0212
Onchocerca volvulus 0.0063 0.0119 0.0213
Trichomonas vaginalis glucosylceramidase, putative 0.0544 0.1453 0.2594
Brugia malayi MAP kinase sur-1 0.005 0.0084 0.0143
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Echinococcus multilocularis purine nucleoside phosphorylase 0.0153 0.037 0.0369
Giardia lamblia Pyruvate kinase 0.0036 0.0045 0.0422
Schistosoma mansoni hypothetical protein 0.009 0.0195 0.0195
Leishmania major cathepsin L-like protease 0.0038 0.0051 0.0084
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Onchocerca volvulus 0.0043 0.0066 0.0117
Echinococcus granulosus carbonic anhydrase 0.1164 0.3171 0.317
Trypanosoma cruzi PAB1-binding protein , putative 0.0126 0.0296 0.05
Loa Loa (eye worm) DR-78 0.0066 0.0129 0.0215
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0066 0.0066
Onchocerca volvulus 0.0127 0.0299 0.0533
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0043 0.0066 0.0111
Brugia malayi nuclear hormone receptor 0.014 0.0333 0.0565
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Schistosoma mansoni neurotransmitter gated ion channel 0.0112 0.0257 0.0257
Echinococcus multilocularis purine nucleoside phosphorylase 0.0153 0.037 0.0369
Trypanosoma brucei hypothetical protein, conserved 0.0111 0.0255 0.0431
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0018 0.0029
Brugia malayi Nuclear hormone receptor-like 1 0.0074 0.0151 0.0255
Echinococcus granulosus flap endonuclease 1 0.0026 0.0018 0.0017
Schistosoma mansoni thyroid hormone receptor 0.014 0.0333 0.0333
Trypanosoma brucei polo-like protein kinase 0.0102 0.0227 0.0385
Plasmodium vivax pyruvate kinase, putative 0.0036 0.0045 0.0671
Loa Loa (eye worm) matrixin family protein 0.122 0.3325 0.5634
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0079 0.014
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0257 0.0436
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0183 0.0454 0.0769
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0038 0.0053 0.0155
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0426 0.1126 0.3422
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.006 0.0106
Onchocerca volvulus Cathepsin F homolog 0.0038 0.0051 0.0092
Echinococcus multilocularis carbonic anhydrase 0.1164 0.3171 0.317
Onchocerca volvulus 0.0111 0.0255 0.0455
Mycobacterium ulcerans bifunctional Mta/Sah nucleosidase Mtn 0.0032 0.0034 0.0097
Echinococcus multilocularis Smad4 0.0025 0.0017 0.0016
Trypanosoma cruzi cysteine peptidase, putative 0.0145 0.0348 0.0589
Schistosoma mansoni hypothetical protein 0.2152 0.5905 0.5905
Schistosoma mansoni inositol monophosphatase 0.0078 0.0161 0.0161
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0049 0.0083 0.0137
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0021 0.0004 0.0005
Echinococcus granulosus geminin 0.2152 0.5905 0.5905
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0038 0.0053 0.0089
Trypanosoma brucei PAB1-binding protein , putative 0.0126 0.0296 0.05
Trypanosoma brucei cytochrome P450, putative 0.0058 0.0106 0.0179
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0046 0.0081
Trypanosoma cruzi DNA topoisomerase II, putative 0.0041 0.006 0.0101
Trypanosoma brucei trypanothione reductase 0.0187 0.0463 0.0785
Loa Loa (eye worm) melatonin receptor type 1A 0.0043 0.0066 0.0108
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0041 0.006 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0066 0.0065
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0043 0.0066 0.0065
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0032 0.0034 0.0057
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Echinococcus multilocularis thioredoxin glutathione reductase 0.0187 0.0465 0.0465
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.004 0.0067
Loa Loa (eye worm) hypothetical protein 0.0066 0.0129 0.0215
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0034 0.0042 0.0041
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0004 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0043 0.0066 0.0108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.0348 0.0589
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.014 0.0333 0.0333
Brugia malayi Matrixin family protein 0.0505 0.1344 0.2277
Echinococcus multilocularis carbonic anhydrase 0.1164 0.3171 0.317
Leishmania major pyruvate kinase 0.0036 0.0045 0.0073
Echinococcus granulosus g protein coupled receptor 0.0043 0.0066 0.0065
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.0121 0.0282 0.0282
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0111 0.0255 0.0431
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0017 0.0025
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0032 0.0034 0.0326
Onchocerca volvulus 0.0066 0.0129 0.023
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.1835 0.5028 0.5027
Loa Loa (eye worm) hypothetical protein 0.0243 0.062 0.1048
Echinococcus multilocularis neuropeptide receptor A26 0.1026 0.2788 0.2787

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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