Detailed information for compound 1376749

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 331.229 | Formula: C12H15BrN2O2S
  • H donors: 0 H acceptors: 1 LogP: 2.85 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1ccc(cc1)CN1CCSC1=N.Br
  • InChi: 1S/C12H14N2O2S.BrH/c1-16-11(15)10-4-2-9(3-5-10)8-14-6-7-17-12(14)13;/h2-5,13H,6-8H2,1H3;1H
  • InChiKey: NMIXWGIPVXWVRK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.083 0.502
Brugia malayi SEA domain containing protein 0.0288 0.4851 0.6498
Loa Loa (eye worm) hypothetical protein 0.0081 0.1182 0.1563
Mycobacterium tuberculosis Conserved protein 0.0043 0.0507 0.1039
Schistosoma mansoni factor for adipocyte differentiation 0.0031 0.0276 0.0397
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0276 0.0344
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0121
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0315 0.0396
Plasmodium falciparum metacaspase-like protein 0.0027 0.0221 0.1044
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0023 0.0003
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0252 0.1205
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0047 0.0562 0.0574
Mycobacterium ulcerans beta-lactamase 0.0043 0.0507 0.2913
Leishmania major GTP-binding protein, putative 0.0021 0.0103 0.0625
Onchocerca volvulus 0.0043 0.0507 0.0654
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0026 0.0204 0.0184
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0026 0.0192 0.0363
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0192 0.0967
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0029 0.0251 0.1202
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0021 0.011 0.0666
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0276 0.0344
Brugia malayi Valyl-tRNA synthetase 0.0023 0.0142 0.0163
Echinococcus multilocularis caspase 0.0027 0.0221 0.0212
Trypanosoma brucei DNA polymerase eta, putative 0.0081 0.1176 0.7117
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0021 0.003
Echinococcus multilocularis cysteine protease 0.0016 0.0021 0.0001
Echinococcus granulosus dna polymerase eta 0.0081 0.1176 0.1158
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0041 0.0028
Onchocerca volvulus 0.0047 0.0562 0.0728
Brugia malayi Muscle positioning protein 4 0.0288 0.4851 0.6498
Echinococcus granulosus 5'partial|Low density lipoprotein receptor class A cysteine rich 0.0047 0.0562 0.0542
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0103 0.0432
Plasmodium falciparum thioredoxin reductase 0.0029 0.0251 0.1202
Loa Loa (eye worm) UNCoordinated family member 0.0031 0.0276 0.0344
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Brugia malayi Kelch motif family protein 0.0021 0.011 0.0121
Echinococcus multilocularis transfer RNA-Phe 0.0031 0.0276 0.0271
Loa Loa (eye worm) hypothetical protein 0.0047 0.0562 0.0728
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.1482 0.8969
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0394 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0142 0.0548
Brugia malayi myotactin form A 0.0031 0.0276 0.0344
Trypanosoma brucei DNA polymerase IV, putative 0.0075 0.1075 0.6508
Brugia malayi PHD-finger family protein 0.003 0.0269 0.0334
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0276 0.0344
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0026 0.0192 0.0967
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0047 0.0562 0.0574
Echinococcus multilocularis dna polymerase eta 0.0081 0.1176 0.1224
Entamoeba histolytica hypothetical protein 0.0088 0.13 0.7843
Giardia lamblia Pyruvate kinase 0.0033 0.0315 0.2013
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0192 0.0231
Loa Loa (eye worm) DPY-31 protein 0.0021 0.011 0.0121
Echinococcus granulosus pyruvate kinase 0.0017 0.0032 0.0011
Brugia malayi TAR-binding protein 0.0065 0.0897 0.1179
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0276 0.0344
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0295 0.037
Schistosoma mansoni myosin-binding protein-related 0.0031 0.0276 0.0397
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0193 0.1168
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0803 0.0784
Trypanosoma cruzi metacaspase, putative 0.0027 0.0221 0.1336
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0315 0.1905
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0026 0.0192 0.0363
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0142 0.0548
Echinococcus granulosus Mastin 0.0057 0.0741 0.0722
Schistosoma mansoni hypothetical protein 0.0021 0.011 0.0158
Loa Loa (eye worm) helicase 0.0023 0.0142 0.0163
Brugia malayi enteropeptidase precursor 0.0047 0.0562 0.0728
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0019 0.0067 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0067 0.0062
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0276 0.0344
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0399 0.038
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0256 0.1068
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0021 0.011 0.0666
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0221 0.0907
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0026 0.0192 0.0363
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0741 0.1065
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0193 0.1168
Echinococcus granulosus roundabout 2 0.0031 0.0276 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.1131 0.5033
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0771 0.101
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0025 0.0173 0.0248
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0213 0.3522 1
Schistosoma mansoni pyruvate kinase 0.0017 0.0032 0.0046
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0103 0.0432
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0755 0.4139
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0251 0.152
Schistosoma mansoni hypothetical protein 0.0031 0.0276 0.0397
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.1652 0.2195
Brugia malayi Bromodomain containing protein 0.0038 0.0401 0.0512
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0315 0.0626
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0507 0.2913
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0137 0.0117
Schistosoma mansoni cpg binding protein 0.0032 0.0303 0.0435
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0026 0.0192 0.0363
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1652 0.7394
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0193 0.1168
Brugia malayi steroid hormone receptor 0.0019 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0069 0.0966 0.1272
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.1652 1
Echinococcus multilocularis anosmin 1 0.0031 0.0276 0.0271
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0019 0.0067 0.0096
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0023 0.0142
Schistosoma mansoni lozenge 0.0054 0.0702 0.1009
Onchocerca volvulus Bile acid receptor homolog 0.0019 0.0067 0.0062
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0507 0.0487
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0444 0.0638
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0084 0.1228 0.2589
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0394 0.0567
Leishmania major tyrosine specific protein phosphatase, putative 0.0016 0.0021 0.0125
Brugia malayi CUB domain containing protein 0.0021 0.011 0.0121
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0251 0.152
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0019 0.0067 0.0062
Brugia malayi Importin beta-1 subunit 0.0028 0.0236 0.029
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0055 0.0708 0.0729
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0047 0.0562 0.0728
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0137 0.0831
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1652 0.7394
Onchocerca volvulus 0.0047 0.0562 0.0728
Schistosoma mansoni pyruvate kinase 0.0033 0.0315 0.0453
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0741 0.1065
Trypanosoma cruzi DNA polymerase kappa, putative 0.0082 0.1196 0.7241
Schistosoma mansoni cell adhesion molecule 0.0031 0.0276 0.0397
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0163
Plasmodium falciparum MO15-related protein kinase 0.0124 0.194 1
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0036 0.0217
Brugia malayi Bromodomain containing protein 0.0075 0.107 0.1411
Loa Loa (eye worm) hypothetical protein 0.0081 0.1182 0.1563
Schistosoma mansoni cell adhesion molecule 0.0031 0.0276 0.0397
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0054 0.0078
Echinococcus multilocularis titin 0.0031 0.0276 0.0271
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0026 0.0192 0.0363
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0142 0.0548
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Schistosoma mansoni chromobox protein 0.0023 0.0142 0.0203
Echinococcus multilocularis dual specificity 0.0088 0.13 0.1356
Echinococcus multilocularis Phosphotidylinositol phosphatase PTPRQ 0.0031 0.0276 0.0271
Echinococcus granulosus pyruvate kinase 0.0017 0.0032 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0524 0.3173
Leishmania major pyruvate kinase 0.0033 0.0315 0.1905
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0276 0.0344
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1482 0.6622
Brugia malayi Lectin C-type domain containing protein 0.0021 0.011 0.0121
Echinococcus multilocularis muscleblind protein 0.0146 0.2337 0.2455
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0026 0.0192 0.0363
Plasmodium falciparum DNA repair protein REV1, putative 0.0017 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0087 0.1281 0.1696
Schistosoma mansoni neuroglian 0.0031 0.0276 0.0397
Brugia malayi Cathepsin L-like precursor 0.0016 0.0021 0.0001
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0021 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0142 0.0548
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0269 0.1399
Plasmodium falciparum heterochromatin protein 1 0.0023 0.0142 0.0631
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0252 0.1303
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0057 0.0741 0.0969
Onchocerca volvulus 0.0021 0.011 0.0121
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0141 0.0545
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0027 0.0221 0.0212
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0221 0.0907
Brugia malayi 6-phosphofructokinase 0.0108 0.1652 0.2195
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0021 0.0001
Echinococcus granulosus Netrin receptor DCC 0.0031 0.0276 0.0256
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0142 0.0548
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.083 0.502
Echinococcus multilocularis 0.0026 0.0192 0.0182
Leishmania major protein kinase, putative 0.0019 0.0074 0.0445
Onchocerca volvulus 0.0031 0.0276 0.0344
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0884 0.1162
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0803 0.0829
Brugia malayi SPRY domain containing protein 0.0031 0.0276 0.0344
Trypanosoma brucei Metacaspase-4 0.0027 0.0221 0.1336
Leishmania major trypanothione reductase 0.0084 0.1228 0.7429
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0026 0.0192 0.0363
Onchocerca volvulus 0.0025 0.0173 0.0205
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0192 0.3142 0.6705
Toxoplasma gondii ABC1 family protein 0.0043 0.0507 0.2739
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0021 0.0003
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0021 0.0001
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0026 0.0192 0.0363
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0021 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Loa Loa (eye worm) steroid hormone receptor 0.0019 0.0067 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0256 0.1068
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0741 0.1065
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0026 0.0192 0.0967
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0269 0.0263
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0019 0.0067 0.0049
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0026 0.0192 0.0363
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0507 0.0945
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0067 0.0049
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0507 0.1039
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0142 0.0548
Onchocerca volvulus 0.0031 0.0276 0.0344
Brugia malayi hypothetical protein 0.0087 0.1289 0.1706
Schistosoma mansoni aryl hydrocarbon receptor 0.0053 0.0677 0.0974
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0047 0.0562 0.0574
Entamoeba histolytica hypothetical protein 0.0037 0.0394 0.2289
Brugia malayi polk-prov protein 0.0044 0.0524 0.0678
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0062
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0103 0.0625
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0252 0.1047
Echinococcus multilocularis Fibronectin type III domain containing protein 0.0031 0.0276 0.0271
Echinococcus granulosus glycoprotein Antigen 5 0.0057 0.0741 0.0722
Brugia malayi zinc metalloproteinase toh-2 precursor 0.0021 0.011 0.0121
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0057 0.0741 0.0763
Leishmania major cathepsin L-like protease 0.0062 0.083 0.502
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0047 0.0562 0.0728
Onchocerca volvulus 0.0031 0.0276 0.0344
Schistosoma mansoni cell adhesion molecule 0.0031 0.0276 0.0397
Echinococcus multilocularis pyruvate kinase 0.0033 0.0315 0.0312
Loa Loa (eye worm) hypothetical protein 0.0057 0.0741 0.0969
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0236 0.1428
Brugia malayi N-terminal motif family protein 0.0197 0.3236 0.4325
Plasmodium falciparum importin beta, putative 0.0028 0.0236 0.1123
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0139 0.0725
Onchocerca volvulus 0.0299 0.5046 0.6761
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0276 0.0344
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0137 0.0831
Toxoplasma gondii cytochrome p450 superfamily protein 0.0026 0.0192 0.0967
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.083 0.502
Echinococcus multilocularis neuropilin (nrp) and tolloid (tll) 0.0021 0.011 0.0095
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0142 0.0548
Echinococcus multilocularis CUB 0.0021 0.011 0.0095
Loa Loa (eye worm) hypothetical protein 0.0068 0.0938 0.1235
Leishmania major cathepsin L-like protease 0.0016 0.0021 0.0127
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0019 0.0067 0.0096
Brugia malayi Fibronectin type III domain containing protein 0.0031 0.0276 0.0344
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0221 0.0907
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0221 0.0907
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0098 0.1482 0.1464
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0026 0.0192 0.0363
Schistosoma mansoni tripartite motif protein trim9 0.0031 0.0276 0.0397
Loa Loa (eye worm) hypothetical protein 0.0068 0.0938 0.1235
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.083 0.502
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0026 0.0192 0.0967
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0884 0.5351
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0026 0.0192 0.0967
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0026 0.0192 0.0967
Schistosoma mansoni hypothetical protein 0.0021 0.011 0.0158
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0023 0.0142
Loa Loa (eye worm) hypothetical protein 0.0043 0.0507 0.0654
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.1196 0.7241
Plasmodium vivax hypothetical protein, conserved 0.003 0.0269 0.1294
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0251 0.152
Trypanosoma brucei DNA polymerase IV, putative 0.0082 0.1196 0.7241
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.4674 1
Echinococcus granulosus flap endonuclease 1 0.0026 0.0193 0.0173
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0276 0.0344
Schistosoma mansoni single-minded 0.0053 0.0677 0.0974
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0031 0.0276 0.0344
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0098 0.1482 0.1966
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0047 0.0562 0.0574
Brugia malayi CUB domain containing protein 0.0021 0.011 0.0121
Brugia malayi RNA, U transporter 1 0.008 0.1163 0.1537
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0019 0.0067 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.13 0.187
Brugia malayi PAS domain containing protein 0.0053 0.0677 0.0883
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0029 0.0251 0.152
Brugia malayi Cytochrome P450 family protein 0.0026 0.0192 0.0231
Brugia malayi CUB domain containing protein 0.0021 0.011 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0221 0.0907
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0029 0.0251 0.1332
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0026 0.0192 0.0967
Echinococcus multilocularis neuroglian 0.0031 0.0276 0.0271
Schistosoma mansoni cell adhesion molecule 0.0031 0.0276 0.0397
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0507 0.3066
Brugia malayi Thioredoxin reductase 0.0084 0.1228 0.1624
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0019 0.0067 0.0047
Loa Loa (eye worm) hypothetical protein 0.0047 0.0562 0.0728
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0047 0.0562 0.0728
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0047 0.0563 0.081
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0047 0.0562 0.0728
Echinococcus granulosus Fibronectin type III 0.0031 0.0276 0.0256
Echinococcus granulosus zinc finger protein 0.0021 0.0103 0.0083
Brugia malayi jmjC domain containing protein 0.0099 0.1487 0.1973
Onchocerca volvulus 0.0031 0.0276 0.0344
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0193 0.0973
Echinococcus granulosus enteropeptidase 0.0057 0.0741 0.0722
Mycobacterium ulcerans hypothetical protein 0.0043 0.0507 0.2913
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0023 0.0004
Plasmodium vivax metacaspase 1, putative 0.0027 0.0221 0.1044
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0741 0.1065
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0063 0.0846 0.1217
Onchocerca volvulus 0.0031 0.0276 0.0344
Brugia malayi Nematode astacin protease protein 30 0.0021 0.011 0.0121
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0047 0.0563 0.0575
Onchocerca volvulus 0.0016 0.0021 0.0001
Brugia malayi Suppressor of lurcher protein 1 precursor 0.0021 0.011 0.0121
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0021 0.0002
Loa Loa (eye worm) hypoxia-induced factor 1 0.0164 0.2654 0.3543
Echinococcus granulosus FTZ F1 alpha 0.0019 0.0067 0.0047
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0026 0.0192 0.0363
Echinococcus multilocularis Chromobox protein 3 0.0023 0.0142 0.0128
Echinococcus granulosus titin 0.0032 0.0295 0.0275
Giardia lamblia Pyruvate kinase 0.0017 0.0032 0.0076
Echinococcus granulosus nephrin 0.0031 0.0276 0.0256
Brugia malayi Trypsin family protein 0.0057 0.0741 0.0969
Brugia malayi Muscleblind-like protein 0.0146 0.2337 0.3117
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0047 0.0563 0.0575
Onchocerca volvulus Putative cubilin 0.0021 0.011 0.0121
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Echinococcus multilocularis Fibronectin, type III 0.0031 0.0276 0.0271
Brugia malayi Cathepsin L-like precursor 0.0016 0.0021 0.0001
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0213 0.3522 0.7523
Echinococcus granulosus dual specificity 0.0088 0.13 0.1283
Brugia malayi SET domain containing protein 0.0025 0.0173 0.0205
Onchocerca volvulus Terribly reduced optic lobes homolog 0.0047 0.0562 0.0728
Leishmania major DNA polymerase eta, putative 0.0043 0.0504 0.3048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.083 0.502
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0047 0.0562 0.0728
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0047 0.0563 0.0575
Trypanosoma brucei DNA polymerase IV, putative 0.0082 0.1196 0.7241
Loa Loa (eye worm) hypothetical protein 0.0081 0.1182 0.1563
Schistosoma mansoni protein tyrosine phosphatase 0.0016 0.0021 0.003
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0026 0.0192 0.0967
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0507 0.2202
Loa Loa (eye worm) hypothetical protein 0.0038 0.0402 0.0514
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.0251 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Brugia malayi CUB domain containing protein 0.0021 0.011 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0057 0.0741 0.0722
Entamoeba histolytica Ran family GTPase 0.0021 0.0103 0.0507
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0276 0.1669
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0029 0.0251 0.0244
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0067 0.0096
Trypanosoma cruzi DNA damage repair protein, putative 0.0017 0.0036 0.0217
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0142 0.0631
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0031 0.0276 0.0271
Loa Loa (eye worm) trypsin family protein 0.0057 0.0741 0.0969
Trypanosoma cruzi trypanothione reductase, putative 0.0084 0.1228 0.7429
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0507 0.2202
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.1196 0.7241
Plasmodium vivax vivapain-2 0.0016 0.0021 0.0003
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0021 0.0001
Mycobacterium ulcerans DNA polymerase IV 0.0082 0.1196 0.718
Loa Loa (eye worm) hypothetical protein 0.0018 0.0062 0.0056
Leishmania major pyruvate kinase 0.0033 0.0315 0.1905
Echinococcus multilocularis pyruvate kinase 0.0017 0.0032 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0067 0.0062
Schistosoma mansoni hypothetical protein 0.0057 0.0741 0.1065
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0846 0.0828
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0741 0.1065
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0021 0.0114 0.0125
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0252 0.1047
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0088 0.13 0.787
Echinococcus multilocularis Netrin receptor DCC 0.0031 0.0276 0.0271
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0032 0.0295 0.037
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.1482 0.2131
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0213 0.3522 0.7523
Onchocerca volvulus 0.0019 0.0067 0.0062
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0047 0.0562 0.0728
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.1652 0.2195
Loa Loa (eye worm) hypothetical protein 0.0027 0.0221 0.027
Echinococcus granulosus CUB 0.0021 0.011 0.009
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.6954 0.7348
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0103 0.0625
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1652 1
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0043 0.0504 0.2722
Brugia malayi astacin protease protein 30 0.0021 0.011 0.0121
Plasmodium falciparum flap endonuclease 1 0.0026 0.0193 0.0899
Brugia malayi hypothetical protein 0.0031 0.0276 0.0344
Loa Loa (eye worm) hypothetical protein 0.0288 0.4851 0.6498
Schistosoma mansoni hypothetical protein 0.0057 0.0741 0.1065
Leishmania major cytochrome p450-like protein 0.0026 0.0192 0.1162
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0023 0.0142 0.0163
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0029 0.0251 0.1332
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0019 0.0067 0.0062
Echinococcus multilocularis pyruvate kinase 0.0017 0.0032 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.083 0.502
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0252 0.0101
Onchocerca volvulus 0.0016 0.0021 0.0001
Loa Loa (eye worm) hypothetical protein 0.0047 0.0562 0.0728
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0142 0.0741
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0085 0.1238 0.1637
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0021 0.0001
Loa Loa (eye worm) hypothetical protein 0.0047 0.0562 0.0728
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0029 0.0251 0.0489
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.1652 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0023 0.0016
Schistosoma mansoni DNA polymerase eta 0.0081 0.1176 0.1691
Schistosoma mansoni ap endonuclease 0.0023 0.0137 0.0197
Schistosoma mansoni titin 0.0032 0.0295 0.0424
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0315 0.0396
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0016 0.0021 0.0125
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0192 0.3142 0.8858
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0193 0.118
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0221 0.0907
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0269 0.1399
Echinococcus granulosus dnaJ subfamily B 0.0406 0.6954 0.6948
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0236 0.1214
Plasmodium vivax heterochromatin protein 1, putative 0.0023 0.0142 0.0631
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0897 0.1289
Brugia malayi Cathepsin L-like precursor 0.0016 0.0021 0.0001
Echinococcus granulosus EG95 0.0031 0.0276 0.0256
Echinococcus multilocularis glycoprotein Antigen 5 0.0057 0.0741 0.0763
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0884 0.1271
Leishmania major cathepsin L-like protease 0.0016 0.0021 0.0127
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0026 0.0192 0.0363
Trypanosoma cruzi metacaspase, putative 0.0027 0.0221 0.1336
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0026 0.0192 0.0967
Onchocerca volvulus 0.0016 0.0021 0.0001
Giardia lamblia DNA damage repair protein 0.0017 0.0036 0.0104
Loa Loa (eye worm) hypothetical protein 0.003 0.0269 0.0334
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0163
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0026 0.0192 0.0967
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Brugia malayi CHD4 protein 0.0026 0.0204 0.0247
Loa Loa (eye worm) hypothetical protein 0.0047 0.0562 0.0728
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0276 0.0344
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0192 0.1162
Schistosoma mansoni zinc finger protein 0.0021 0.0103 0.0149
Trypanosoma cruzi metacaspase, putative 0.0027 0.0221 0.1336
Brugia malayi Calcium binding EGF domain containing protein 0.0047 0.0562 0.0728
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0606 0.2652
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0741 0.1065
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0067 0.0062
Plasmodium falciparum phd finger protein, putative 0.003 0.0269 0.1294
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0394 0.0396
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0031 0.0276 0.0344
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0192 0.1162
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0315 0.0396
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0026 0.0204 0.0194
Trypanosoma brucei unspecified product 0.0075 0.1075 0.6508
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0276 0.0344
Echinococcus granulosus tar DNA binding protein 0.0065 0.0897 0.0878
Trypanosoma brucei metacaspase MCA2 0.0027 0.0221 0.1336
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0137 0.0245
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0047 0.0563 0.073
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0031 0.0276 0.0271
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0019 0.0067 0.0062
Echinococcus granulosus basement membrane specific heparan sulfate 0.0047 0.0562 0.0542
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0029 0.0251 0.1332
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0036 0.0217
Schistosoma mansoni SET domain protein 0.0034 0.0346 0.0498
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0236 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0203 0.0827
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0256 0.1068
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1482 0.6622
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0137 0.0628
Brugia malayi Protein kinase domain containing protein 0.0088 0.13 0.1722
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0897 0.1289
Echinococcus granulosus peregrin 0.0042 0.0485 0.0465
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0478 0.0459
Brugia malayi follicle stimulating hormone receptor 0.0253 0.4227 0.5658
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0055 0.0708 0.0689
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0192 0.3142 0.6705
Trypanosoma brucei metacaspase 0.0027 0.0221 0.1336
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0023 0.0003
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0276 0.0344
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0531 0.0686
Echinococcus granulosus transmembrane protease serine 3 0.0057 0.0741 0.0722
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0021 0.0001
Mycobacterium ulcerans DNA polymerase IV 0.0082 0.1196 0.718
Brugia malayi basement membrane proteoglycan precursor 0.0047 0.0562 0.0728
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0897 0.1289
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0032 0.0059
Trypanosoma brucei DNA damage repair protein, putative 0.0017 0.0036 0.0217
Brugia malayi hypothetical protein 0.0057 0.0741 0.0969
Onchocerca volvulus 0.0112 0.1724 0.2292
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0531 0.0763
Loa Loa (eye worm) cysteine protease 0.0016 0.0021 0.0001
Loa Loa (eye worm) hypothetical protein 0.0178 0.29 0.3873
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0047 0.0563 0.0544
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0121
Brugia malayi Bromodomain containing protein 0.0032 0.031 0.039
Schistosoma mansoni hypothetical protein 0.0016 0.002 0.0029
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0098 0.1482 0.8969
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0741 0.1065
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0103 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0606 0.2652
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0047 0.0563 0.081
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0067 0.0062
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.1482 0.8956
Loa Loa (eye worm) hypothetical protein 0.0299 0.5046 0.6761
Giardia lamblia DINP protein human, muc B family 0.0062 0.0829 0.5534
Brugia malayi Trypsin family protein 0.0299 0.5046 0.6761
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0269 0.0386
Mycobacterium tuberculosis Probable reductase 0.0192 0.3142 0.6705
Echinococcus granulosus Netrin receptor DCC 0.0031 0.0276 0.0256
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0057 0.0741 0.1065
Schistosoma mansoni DNA polymerase IV / kappa 0.0017 0.0036 0.0052
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0741 0.1065
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0193 0.0781
Trypanosoma brucei trypanothione reductase 0.0084 0.1228 0.7429
Schistosoma mansoni cell adhesion molecule 0.0031 0.0276 0.0397
Echinococcus granulosus anosmin 1 0.0031 0.0276 0.0256
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0315 0.0396
Trypanosoma brucei unspecified product 0.0038 0.0406 0.2454
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0269 0.0334
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0252 0.1047
Schistosoma mansoni retinoic acid receptor RXR 0.0019 0.0067 0.0096
Echinococcus multilocularis cell adhesion molecule 0.0031 0.0276 0.0271
Echinococcus granulosus single minded 2 0.0039 0.0432 0.0412
Entamoeba histolytica hypothetical protein 0.0037 0.0394 0.2289
Echinococcus granulosus pyruvate kinase 0.0033 0.0315 0.0295
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0897 0.1179
Schistosoma mansoni hemicentin 0.0031 0.0276 0.0397
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0027 0.0221 0.0317
Plasmodium vivax importin-beta 2, putative 0.0028 0.0236 0.1123
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0023 0.0018
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0019 0.0067 0.0049
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0121
Onchocerca volvulus 0.0043 0.0507 0.0654
Mycobacterium tuberculosis Conserved hypothetical protein 0.0055 0.0708 0.1472
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0884 0.5351
Schistosoma mansoni SET domain protein 0.0015 0.0002 0.0002
Echinococcus granulosus low density lipoprotein receptor protein 0.0047 0.0562 0.0542
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.1196 0.7241
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Trypanosoma brucei chrX additional, unordered contigs 0.0017 0.0036 0.0217
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0507 0.2202
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0019 0.0067 0.0096
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0251 0.152
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0029 0.0251 0.0231
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0047 0.0563 0.0544
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.083 0.502
Echinococcus multilocularis Chromo domain 0.0023 0.0142 0.0128
Onchocerca volvulus 0.0288 0.4851 0.6498
Echinococcus multilocularis Netrin receptor DCC 0.0031 0.0276 0.0271
Loa Loa (eye worm) hypothetical protein 0.0044 0.0524 0.0678
Schistosoma mansoni ran 0.0021 0.0103 0.0148
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0252 0.1303
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0021 0.0003
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0192 0.1162
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0524 0.3173
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0527 0.3188
Toxoplasma gondii NADPH-glutathione reductase 0.0029 0.0251 0.1299
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0276 0.0344
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0055 0.0708 0.0925
Entamoeba histolytica protein kinase domain containing protein 0.0088 0.13 0.7843
Schistosoma mansoni coup transcription factor 0.0019 0.0067 0.0096
Schistosoma mansoni flap endonuclease-1 0.0023 0.0149 0.0214
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0062
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0067 0.0047
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0221 0.0907
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0884 0.0865
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0121
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0142 0.0548
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0137 0.0609
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0507 0.1039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0021 0.0002
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0117 0.013
Loa Loa (eye worm) CHromoDomain protein family member 0.0026 0.0204 0.0247
Schistosoma mansoni factor for adipocyte differentiation 0.0031 0.0276 0.0397
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0026 0.0192 0.0363
Brugia malayi myotactin form B 0.0031 0.0276 0.0344
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0062
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0019 0.0067 0.0047
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0252 0.1047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Brugia malayi Calcium binding EGF domain containing protein 0.0021 0.011 0.0121
Mycobacterium ulcerans hypothetical protein 0.0057 0.0741 0.4359
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0057 0.0741 0.1065
Brugia malayi Zinc metalloproteinase toh-2 precursor 0.0021 0.011 0.0121
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0047 0.0562 0.0728
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0432 0.0553
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0047 0.0563 0.081
Onchocerca volvulus 0.0016 0.0021 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0082 0.1196 0.7241
Loa Loa (eye worm) DOMON domain-containing protein 0.0288 0.4851 0.6498
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0507 0.0654
Giardia lamblia Kinase, PLK 0.0098 0.1482 1
Echinococcus multilocularis anosmin 1 0.0031 0.0276 0.0271
Brugia malayi CXXC zinc finger family protein 0.0029 0.024 0.0296
Echinococcus multilocularis zinc finger protein 0.0021 0.0103 0.0088
Echinococcus multilocularis caspase 8 0.0027 0.0221 0.0212
Loa Loa (eye worm) hypothetical protein 0.0028 0.0236 0.029
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0034 0.0346 0.0345
Onchocerca volvulus Alhambra homolog 0.003 0.0269 0.0334
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0023 0.0016
Schistosoma mansoni hypothetical protein 0.0026 0.0192 0.0276
Brugia malayi hypothetical protein 0.0037 0.0394 0.0503
Loa Loa (eye worm) cytochrome P450 family protein 0.0086 0.126 0.1668
Echinococcus granulosus low density lipoprotein receptor ldl 0.0047 0.0562 0.0542
Onchocerca volvulus 0.0016 0.0021 0.0001
Mycobacterium tuberculosis Conserved protein 0.0043 0.0507 0.1039
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0019 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0434 0.7455 1
Leishmania major DNA polymerase kappa, putative 0.0062 0.0829 0.5019
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0026 0.0192 0.1162
Loa Loa (eye worm) hypothetical protein 0.0043 0.0507 0.0654
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0381 0.0383
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0023 0.0004
Toxoplasma gondii exonuclease III APE 0.0023 0.0137 0.0658
Plasmodium vivax thioredoxin reductase, putative 0.0084 0.1228 0.6287
Entamoeba histolytica hypothetical protein 0.0037 0.0394 0.2289
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0047 0.0562 0.0808
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0031 0.0276 0.0344
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0315 0.1905
Entamoeba histolytica hypothetical protein 0.0037 0.0394 0.2289
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.1196 0.7241
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0023 0.0003
Brugia malayi beta-lactamase family protein 0.0043 0.0507 0.0654
Echinococcus multilocularis titin 0.0032 0.0295 0.0291
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0163
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0163
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0163
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0019 0.0067 0.0096
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0251 0.152
Brugia malayi hypothetical protein 0.0021 0.011 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.1131 0.5033
Brugia malayi Steroid receptor seven-up type 2 0.0019 0.0067 0.0062
Schistosoma mansoni hypothetical protein 0.0047 0.0562 0.0808
Loa Loa (eye worm) cytochrome P450 0.0026 0.0192 0.0231
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0098 0.1482 0.1549
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0829 0.5019
Loa Loa (eye worm) hypothetical protein 0.0057 0.0741 0.0969
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0507 0.1039
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0036 0.0217
Trypanosoma cruzi major cysteine proteinase, putative 0.0048 0.0595 0.36
Brugia malayi Trypsin family protein 0.0057 0.0741 0.0969
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0047 0.0562 0.0728
Giardia lamblia NADH oxidase lateral transfer candidate 0.0029 0.0251 0.1577
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.1652 1
Trypanosoma cruzi DNA damage repair protein, putative 0.0017 0.0036 0.0217
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0026 0.0192 0.1162
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.1652 0.3502
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0221 0.1044
Loa Loa (eye worm) hypothetical protein 0.0288 0.4851 0.6498
Echinococcus granulosus pyruvate kinase 0.0033 0.0315 0.0295
Entamoeba histolytica hypothetical protein 0.0023 0.0141 0.0737
Echinococcus multilocularis usherin 0.0031 0.0276 0.0271
Entamoeba histolytica protein kinase, putative 0.0088 0.13 0.7843
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0023 0.0142 0.0682
Echinococcus multilocularis Mastin 0.0057 0.0741 0.0763
Echinococcus granulosus Fibronectin type III domain containing protein 0.0031 0.0276 0.0256
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.1652 0.4385
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0021 0.0002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0082 0.1196 0.7241
Schistosoma mansoni hypothetical protein 0.003 0.0269 0.0386
Echinococcus multilocularis chromobox protein 2 0.0023 0.0142 0.0128
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.1482 0.8969
Schistosoma mansoni ephrin receptor 0.0031 0.0276 0.0397
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0829 0.1192
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0163
Brugia malayi ImpB/MucB/SamB family protein 0.0081 0.1176 0.1554
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0251 0.152
Echinococcus granulosus Chromobox protein 3 0.0023 0.0142 0.0121
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0031 0.001
Entamoeba histolytica hypothetical protein 0.0023 0.0142 0.0741
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0137 0.0529
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0063 0.0846 0.1769
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Brugia malayi Protein-tyrosine phosphatase 0.0128 0.2012 0.2679
Loa Loa (eye worm) hypothetical protein 0.0043 0.0507 0.0654
Echinococcus granulosus thioredoxin glutathione reductase 0.0085 0.1236 0.1218
Trypanosoma cruzi DNA polymerase kappa, putative 0.0082 0.1196 0.7241
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0507 0.0654
Schistosoma mansoni hypothetical protein 0.0047 0.0562 0.0808
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0142 0.0548
Trypanosoma cruzi metacaspase 5, putative 0.0027 0.0221 0.1336
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0031 0.0011
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0141 0.0545
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0846 0.5014
Brugia malayi RNA binding protein 0.0065 0.0897 0.1179
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.083 0.502
Echinococcus multilocularis Protein lozenge 0.0054 0.0702 0.0722
Loa Loa (eye worm) phosphofructokinase 0.0108 0.1652 0.2195
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0251 0.152
Leishmania major cytochrome p450-like protein 0.0026 0.0192 0.1162
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0082 0.1196 0.5328
Schistosoma mansoni pcd6 interacting protein-related 0.0016 0.0021 0.003
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.036 0.036
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0251 0.152
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0276 0.0344
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0063 0.0846 0.1111
Loa Loa (eye worm) hypothetical protein 0.0043 0.0507 0.0654
Loa Loa (eye worm) zinc metalloproteinase toh-2 0.0021 0.011 0.0121
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0192 0.1162
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0103 0.0625
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0021 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0062
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0137 0.0831
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0031 0.0276 0.0344
Schistosoma mansoni terminal deoxycytidyl transferase 0.0055 0.0708 0.1018
Trypanosoma brucei unspecified product 0.0038 0.0406 0.2454
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0507 0.0729
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0221 0.1129
Echinococcus granulosus Low density lipoprotein receptor class A cysteine rich 0.0047 0.0562 0.0542
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0256 0.1068
Schistosoma mansoni jumonji domain containing protein 0.0078 0.1127 0.162
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0432 0.245
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0507 0.3066
Trichomonas vaginalis DNA polymerase eta, putative 0.0082 0.1196 0.5328
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.1626 0.7276
Chlamydia trachomatis pyruvate kinase 0.0033 0.0315 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0103 0.0111
Loa Loa (eye worm) hypothetical protein 0.0047 0.0562 0.0728
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0137 0.0157
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0023 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0021 0.0002
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0142 0.0631
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.083 0.502
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0088 0.13 0.1722
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0029 0.0251 0.1299
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0846 0.5014
Loa Loa (eye worm) hypothetical protein 0.0087 0.1281 0.1696
Echinococcus multilocularis peregrin 0.0042 0.0485 0.0492
Leishmania major cathepsin L-like protease 0.0062 0.083 0.502
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0016 0.0021 0.0125
Leishmania major cytochrome p450-like protein 0.0026 0.0192 0.1162
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0062
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0088 0.13 0.787
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0021 0.0002
Mycobacterium tuberculosis Probable dehydrogenase 0.0192 0.3142 0.6705
Loa Loa (eye worm) thioredoxin reductase 0.0084 0.1228 0.1624
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0897 0.1289
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0031 0.0276 0.0344
Echinococcus multilocularis ecdysone induced protein 78C 0.0019 0.0067 0.0049
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0251 0.152
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0047 0.0563 0.0575
Loa Loa (eye worm) CUB domain-containing protein 0.0021 0.011 0.0121
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.0504 0.3048
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0027 0.0221 0.0201
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0121
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0192 0.3142 0.6705
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0252 0.1205
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0021 0.0003
Loa Loa (eye worm) hypothetical protein 0.0052 0.0651 0.0849
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1652 1
Onchocerca volvulus 0.0039 0.0432 0.0553
Loa Loa (eye worm) hypothetical protein 0.0087 0.1289 0.1706
Leishmania major DNA damage repair protein, putative 0.0017 0.0036 0.0217
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0142 0.0203
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0021 0.0001
Schistosoma mansoni cytochrome P450 0.0026 0.0192 0.0276
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0507 0.1039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0021 0.0002
Onchocerca volvulus 0.0023 0.0142 0.0163
Brugia malayi serine/threonine-protein kinase plk-2 0.0098 0.1482 0.1966
Echinococcus granulosus anosmin 1 0.0031 0.0276 0.0256
Onchocerca volvulus 0.0057 0.0741 0.0969
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0067 0.0047
Brugia malayi hypothetical protein 0.0178 0.29 0.3873
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0741 0.1065
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0884 0.1162
Echinococcus multilocularis cubilin 0.0021 0.011 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0142 0.0548
Loa Loa (eye worm) hypothetical protein 0.0057 0.0741 0.0969
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0253 0.4227 0.5658
Brugia malayi CUB domain containing protein 0.0068 0.0938 0.1235
Brugia malayi hypothetical protein 0.0434 0.7455 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0142 0.0741
Schistosoma mansoni chromobox protein 0.014 0.2227 0.3203
Schistosoma mansoni caspase-7 (C14 family) 0.0027 0.0221 0.0317
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0026 0.0192 0.0363
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0531 0.0686
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0315 0.1905
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0031 0.0044
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0021 0.0001
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0236 0.1428
Loa Loa (eye worm) hypothetical protein 0.0043 0.0506 0.0653
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0067 0.0096
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0047 0.0562 0.0728
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0897 0.1289
Onchocerca volvulus 0.0057 0.0741 0.0969
Trichomonas vaginalis glutathione reductase, putative 0.0029 0.0251 0.1044
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0047 0.0562 0.0574
Schistosoma mansoni nephrin 0.0031 0.0276 0.0397
Loa Loa (eye worm) hypothetical protein 0.0043 0.0507 0.0654
Loa Loa (eye worm) hypothetical protein 0.0047 0.0562 0.0728
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.0021 0.011 0.0158
Trichomonas vaginalis hypothetical protein 0.0023 0.0142 0.0548
Loa Loa (eye worm) beta-lactamase 0.0043 0.0507 0.0654
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0256 0.1068
Brugia malayi Nematode astacin protease protein 30 0.0021 0.011 0.0121
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0021 0.0002
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0021 0.011 0.0121
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0047 0.0563 0.0575
Trichomonas vaginalis esterase, putative 0.0043 0.0507 0.2202
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0029 0.0251 0.152
Brugia malayi Fibronectin type III domain containing protein 0.0031 0.0276 0.0344
Trichomonas vaginalis chromobox protein, putative 0.014 0.2227 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0019 0.0067 0.0062
Echinococcus multilocularis FTZ F1 alpha 0.0019 0.0067 0.0049
Schistosoma mansoni hypothetical protein 0.0302 0.5099 0.7333
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0527 0.3188
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0142 0.0682
Schistosoma mansoni hypothetical protein 0.0406 0.6954 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0019 0.0067 0.0049
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0315 0.0396
Brugia malayi ImpB/MucB/SamB family protein 0.0055 0.0708 0.0925
Echinococcus multilocularis caspase 2 0.0027 0.0221 0.0212
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0315 0.1333
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0884 0.0915
Echinococcus multilocularis pyruvate kinase 0.0033 0.0315 0.0312
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0252 0.1417
Trichomonas vaginalis Heterochromatin protein, putative 0.0023 0.0142 0.0548
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0023 0.0003
Echinococcus multilocularis roundabout 2 0.0031 0.0276 0.0271
Schistosoma mansoni hypothetical protein 0.0031 0.0276 0.0397
Trypanosoma brucei metacaspase MCA3 0.0027 0.0221 0.1336
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0062
Echinococcus multilocularis pyruvate kinase 0.0017 0.0032 0.0012
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0121
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0432 0.0436
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0057 0.0741 0.1065
Onchocerca volvulus 0.0016 0.0021 0.0001
Brugia malayi M-phase phosphoprotein, mpp8 0.0023 0.0142 0.0163
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0155 0.0143
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.0021 0.011 0.0158
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.1196 0.7241
Onchocerca volvulus 0.0031 0.0276 0.0344
Echinococcus multilocularis cysteine protease 0.0016 0.0021 0.0001
Schistosoma mansoni chromobox protein 0.014 0.2227 0.3203
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0221 0.1129
Trypanosoma cruzi Fibronectin type III domain containing protein, putative 0.0031 0.0276 0.1669
Brugia malayi jmjC domain containing protein 0.004 0.0444 0.0569
Echinococcus granulosus chromobox protein 2 0.0023 0.0142 0.0121
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0193 0.1057
Schistosoma mansoni factor for adipocyte differentiation 0.0031 0.0276 0.0397
Echinococcus multilocularis anosmin 1 0.0031 0.0276 0.0271
Schistosoma mansoni hypothetical protein 0.0021 0.011 0.0158
Echinococcus granulosus basement membrane specific heparan sulfate 0.0047 0.0562 0.0542
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0029 0.0251 0.0361
Loa Loa (eye worm) hypothetical protein 0.0081 0.1176 0.1554
Echinococcus granulosus muscleblind protein 0.0146 0.2337 0.2322
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0478 0.0485
Echinococcus multilocularis transmembrane protease serine 3 0.0057 0.0741 0.0763
Schistosoma mansoni importin beta-1 0.0028 0.0236 0.0339
Trypanosoma brucei polo-like protein kinase 0.0098 0.1482 0.8969
Onchocerca volvulus 0.0288 0.4851 0.6498
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0252 0.1205
Onchocerca volvulus 0.0031 0.0276 0.0344
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0036 0.0217
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0103 0.0566
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.083 0.502
Schistosoma mansoni caspase-3 (C14 family) 0.0027 0.0221 0.0317
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0021 0.011 0.0666
Loa Loa (eye worm) hypothetical protein 0.0087 0.1289 0.1706
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0507 0.3066
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0032 0.0295 0.037
Brugia malayi beta-lactamase family protein 0.0043 0.0507 0.0654
Loa Loa (eye worm) heterochromatin protein 1 0.014 0.2227 0.2969
Brugia malayi Flap endonuclease-1 0.0026 0.0193 0.0232
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0142 0.0548
Onchocerca volvulus 0.0031 0.0276 0.0344
Echinococcus multilocularis pyruvate kinase 0.0026 0.0192 0.0182
Loa Loa (eye worm) hypothetical protein 0.004 0.0443 0.0569
Plasmodium vivax glutathione reductase, putative 0.0084 0.1228 0.6287
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0252 0.0756
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.083 0.502
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0137 0.0831
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0047 0.0562 0.0808
Echinococcus multilocularis chromobox protein 1 0.014 0.2227 0.2339
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0023 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0195 0.0789
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0031 0.0276 0.0256
Brugia malayi Cathepsin L-like precursor 0.0016 0.0021 0.0001
Echinococcus granulosus cytochrome P450 2K1 0.0026 0.0192 0.0172
Brugia malayi Cell death protein 3 precursor 0.0027 0.0221 0.027
Leishmania major hypothetical protein, conserved 0.0043 0.0507 0.3066
Plasmodium falciparum glutathione reductase 0.0084 0.1228 0.6287
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0019 0.0067 0.0062
Onchocerca volvulus 0.0062 0.0829 0.1088
Trichomonas vaginalis mercuric reductase, putative 0.0029 0.0251 0.1044
Loa Loa (eye worm) hypothetical protein 0.0146 0.2337 0.3117
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0057 0.0741 0.0763
Trichomonas vaginalis chromobox protein, putative 0.0085 0.1238 0.5514
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0026 0.0192 0.0967
Schistosoma mansoni pyruvate kinase 0.0033 0.0315 0.0453
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0021 0.0002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0507 0.0729
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0276 0.0344
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0047 0.0562 0.0574
Leishmania major cathepsin L-like protease 0.0016 0.0021 0.0127
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0155 0.0135
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0026 0.0192 0.0967
Schistosoma mansoni cpg binding protein 0.0032 0.0303 0.0435
Onchocerca volvulus 0.0021 0.011 0.0121
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0024 0.0157 0.077
Brugia malayi glutathione reductase 0.0084 0.1228 0.1624
Echinococcus granulosus contactin 0.0031 0.0276 0.0256
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0019 0.0067 0.0062
Schistosoma mansoni hypothetical protein 0.0021 0.011 0.0158
Trypanosoma cruzi metacaspase, putative 0.0027 0.0221 0.1336
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0366 0.6252 0.8989
Brugia malayi Fibronectin type III domain containing protein 0.0031 0.0276 0.0344
Brugia malayi Low-density lipoprotein receptor-related protein, putative 0.0047 0.0562 0.0728
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0315 0.1333
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0026 0.0192 0.0363
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.002 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0021 0.0002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0023 0.0003
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0016 0.0021 0.0125
Trypanosoma cruzi Fibronectin type III domain containing protein, putative 0.0031 0.0276 0.1669
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0047 0.0562 0.0728
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0884 0.5292
Echinococcus granulosus low density lipoprotein receptor ldl 0.0047 0.0562 0.0542
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0193 0.0183
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0031 0.0044
Echinococcus granulosus G1Y162 protein 0.0031 0.0276 0.0256
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0047 0.0562 0.0728
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0062 0.0042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0251 0.152
Toxoplasma gondii thioredoxin reductase 0.0084 0.1228 0.6799
Echinococcus multilocularis dna polymerase kappa 0.0082 0.1196 0.1246
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0047 0.0562 0.0728
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0019 0.0067 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0067 0.0049
Brugia malayi hypothetical protein 0.0023 0.0142 0.0163
Loa Loa (eye worm) myotactin form A 0.0031 0.0276 0.0344
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0021 0.003
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0019 0.0067 0.0047
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0507 0.2202
Brugia malayi Cytochrome P450 family protein 0.0086 0.126 0.1668
Echinococcus granulosus caspase 2 0.0027 0.0221 0.0201
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.036 0.034
Onchocerca volvulus 0.0032 0.0295 0.037
Entamoeba histolytica deoxycytidyl transferase, putative 0.0055 0.0708 0.4213
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0531 0.0763
Echinococcus granulosus roundabout 2 0.0031 0.0276 0.0256
Echinococcus granulosus Tolloid protein 1 0.0021 0.011 0.009
Brugia malayi Cathepsin L-like precursor 0.0016 0.0021 0.0001
Loa Loa (eye worm) hypothetical protein 0.0057 0.0741 0.0969
Brugia malayi Fibronectin type III domain containing protein 0.0031 0.0276 0.0344
Echinococcus multilocularis roundabout 2 0.0031 0.0276 0.0271
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0531 0.0511
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0142 0.0548
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0839 0.1101
Echinococcus granulosus titin 0.0032 0.0295 0.0275
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.1196 0.7241
Schistosoma mansoni kinase 0.005 0.0629 0.0904
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0023 0.0034
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Plasmodium falciparum metacaspase 1 0.0027 0.0221 0.1044
Echinococcus multilocularis fibronectin type III domain-containing protein 0.0031 0.0276 0.0271
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0142 0.0203
Onchocerca volvulus 0.0047 0.0562 0.0728
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0016 0.0021 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0527 0.3188
Loa Loa (eye worm) hypothetical protein 0.0079 0.1131 0.1494
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.1652 0.1729
Brugia malayi photoreceptor-specific nuclear receptor 0.0019 0.0067 0.0062
Trypanosoma brucei metacaspase 5, putative 0.0027 0.0221 0.1336
Schistosoma mansoni steroid hormone receptor ad4bp 0.0019 0.0067 0.0096
Onchocerca volvulus 0.0288 0.4851 0.6498
Entamoeba histolytica hypothetical protein 0.0023 0.0142 0.0741
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0017 0.0036 0.0087
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0741 0.1065
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0315 0.0369
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0276 0.0344
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.1196 0.7241
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0029 0.0251 0.152
Onchocerca volvulus 0.0057 0.0741 0.0969
Loa Loa (eye worm) lethal protein 805 0.0031 0.0276 0.0344
Echinococcus granulosus anosmin 1 0.0031 0.0276 0.0256
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0252 0.1047
Leishmania major metacaspase, putative 0.0027 0.0221 0.1336
Loa Loa (eye worm) CUB domain-containing protein 0.0021 0.011 0.0121
Schistosoma mansoni hypothetical protein 0.0021 0.011 0.0158
Echinococcus granulosus ecdysone induced protein 78C 0.0019 0.0067 0.0047
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0026 0.0192 0.0363
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0531 0.0511
Echinococcus granulosus Phosphotidylinositol phosphatase PTPRQ 0.0031 0.0276 0.0256
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.1652 0.1635
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0137 0.0609
Schistosoma mansoni cercarial elastase (S01 family) 0.0057 0.0741 0.1065
Loa Loa (eye worm) hypothetical protein 0.0047 0.0562 0.0728
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0507 0.2202
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0723 0.3184
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.083 0.502
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0062
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0029 0.0251 0.1202
Schistosoma mansoni ap endonuclease 0.0023 0.0137 0.0197
Mycobacterium ulcerans lipase LipD 0.0043 0.0507 0.2913
Mycobacterium tuberculosis Probable oxidoreductase 0.0213 0.3522 0.7523
Trichomonas vaginalis ran, putative 0.0021 0.0103 0.0375
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0088 0.13 0.787
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.1652 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0019 0.0067 0.0049
Leishmania major hypothetical protein, conserved 0.0031 0.0276 0.1669
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0099 0.1487 0.1554
Loa Loa (eye worm) hypothetical protein 0.0098 0.1469 0.1949
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0897 0.1179
Schistosoma mansoni hypothetical protein 0.0023 0.0142 0.0203
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0121
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0256 0.1068
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0062 0.0089
Trypanosoma brucei DNA damage repair protein, putative 0.0017 0.0036 0.0217
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.083 0.502
Schistosoma mansoni hypothetical protein 0.002 0.0093 0.0134
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0531 0.0541
Brugia malayi hypothetical protein 0.0031 0.0276 0.0344
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0507 0.2913
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.083 0.502
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0531 0.0541
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0055 0.0708 0.1018
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0252 0.1303
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0078 0.1117 0.1607
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0221 0.0907
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0221 0.1129
Leishmania major hypothetical protein, conserved 0.0016 0.002 0.0123
Echinococcus granulosus cathepsin l1 0.0016 0.0021 0.0001
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0047 0.0563 0.0544
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0026 0.0192 0.0967
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0026 0.0192 0.0967
Echinococcus multilocularis roundabout 2 0.0031 0.0276 0.0271
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0026 0.0192 0.0363
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0221 0.0907
Toxoplasma gondii cell-cycle-associated protein kinase, putative 0.0116 0.1796 1
Echinococcus multilocularis Tolloid protein 1 0.0021 0.011 0.0095
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0197 0.3236 0.4325
Echinococcus granulosus chromobox protein 1 0.014 0.2227 0.2212
Plasmodium falciparum glutathione reductase 0.0029 0.0251 0.1202
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.083 0.502
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0252 0.1047
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0884 0.5351
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0193 0.0899
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0047 0.0563 0.081
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0026 0.0192 0.0363
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0062 0.0829 0.1732
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0016 0.0021 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1482 0.6622
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0193 0.0232
Loa Loa (eye worm) hypothetical protein 0.0197 0.3236 0.4325
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0897 0.1179
Plasmodium vivax DNA repair protein REV1, putative 0.0017 0.0036 0.0081
Trypanosoma cruzi DNA polymerase eta, putative 0.0081 0.1176 0.7117
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0444 0.0424
Entamoeba histolytica hypothetical protein 0.0023 0.0142 0.0741
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0137 0.0715
Loa Loa (eye worm) runx1 0.0054 0.0702 0.0917
Schistosoma mansoni eyes absent homolog 0.0087 0.1289 0.1854
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0141 0.0853
Loa Loa (eye worm) hypothetical protein 0.0299 0.5046 0.6761
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0026 0.0192 0.0363
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.1196 0.7241
Schistosoma mansoni protein tyrosine phosphatase 0.0016 0.0021 0.003
Brugia malayi phosphofructokinase 0.0108 0.1652 0.2195
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0031 0.0276 0.0344
Onchocerca volvulus 0.0043 0.0507 0.0654
Loa Loa (eye worm) hypothetical protein 0.0023 0.0139 0.0159
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1482 0.6622
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0026 0.0192 0.0967
Echinococcus multilocularis enteropeptidase 0.0057 0.0741 0.0763
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0067 0.0096
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0139 0.0159
Schistosoma mansoni chromobox protein 0.0023 0.0142 0.0203
Loa Loa (eye worm) RNA binding protein 0.0065 0.0897 0.1179
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0256 0.1068
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0507 0.0515
Brugia malayi nuclear hormone receptor 0.0019 0.0067 0.0062
Onchocerca volvulus 0.0047 0.0562 0.0728
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0251 0.152
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0021 0.0003
Echinococcus multilocularis low density lipoprotein receptor protein 0.0047 0.0562 0.0574
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0142 0.0548
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0547 0.9457 0.9456
Schistosoma mansoni hypothetical protein 0.0031 0.0276 0.0397
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0047 0.0562 0.0808
Loa Loa (eye worm) hypothetical protein 0.0062 0.0829 0.1088
Loa Loa (eye worm) hypothetical protein 0.0033 0.0315 0.0396
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0019 0.0067 0.0049
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0252 0.1582
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0142 0.0631
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0021 0.0114 0.0125
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0093 0.0098
Schistosoma mansoni hypothetical protein 0.0037 0.0394 0.0567
Echinococcus granulosus cell adhesion molecule 0.0031 0.0276 0.0256
Onchocerca volvulus 0.0288 0.4851 0.6498
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.024 0.0296
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0062 0.0044
Echinococcus granulosus cpg binding protein 0.0032 0.0303 0.0283
Echinococcus multilocularis cubilin 0.0021 0.011 0.0095
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0507 0.2533
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0142 0.0741
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Entamoeba histolytica protein kinase, putative 0.0088 0.13 0.7843
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0444 0.0638
Brugia malayi nuclear receptor NHR-88 0.0019 0.0067 0.0062
Brugia malayi chromobox protein homolog 3 0.0079 0.1131 0.1494
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0103 0.0088
Brugia malayi Trypsin family protein 0.0057 0.0741 0.0969
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0846 0.0875
Loa Loa (eye worm) hypothetical protein 0.0047 0.0562 0.0728
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0029 0.0251 0.1202
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0103 0.0467
Brugia malayi Trypsin-like protease protein 5 0.0057 0.0741 0.0969
Loa Loa (eye worm) calcium binding EGF domain-containing protein 0.0047 0.0562 0.0728
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0252 0.1205
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0029 0.0251 0.1202
Brugia malayi protein unc-22 0.0032 0.0295 0.037
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0137 0.0529
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0023 0.0142
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0315 0.0396
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0192 0.0231
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0315 0.1726
Onchocerca volvulus Cell death protein 3 homolog 0.0027 0.0221 0.027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0019 0.0067 0.0062
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0315 0.1658
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0034 0.0346 0.0327
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0142 0.0203
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0057 0.0741 0.1065
Leishmania major cathepsin L-like protease 0.0016 0.0021 0.0127
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0221 0.0907
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0192 0.1162
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0019 0.0067 0.0062
Echinococcus granulosus usherin 0.0031 0.0276 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.011 0.0405
Brugia malayi Lethal protein 805 0.0031 0.0276 0.0344
Brugia malayi Fibronectin type III domain containing protein 0.0031 0.0276 0.0344
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0192 0.0231
Trichomonas vaginalis chromobox protein, putative 0.014 0.2227 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0562 0.0728
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0019 0.0067 0.0062
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1652 0.7394
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1652 0.7394
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0067 0.0062
Loa Loa (eye worm) ctsf protein 0.0016 0.0021 0.0001
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0026 0.0192 0.1162
Schistosoma mansoni titin 0.0031 0.0276 0.0397
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0531 0.0763
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0026 0.0204 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0295 0.0424
Onchocerca volvulus 0.0023 0.0142 0.0163
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0142 0.0548
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0252 0.1047
Onchocerca volvulus 0.0047 0.0562 0.0728
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0021 0.0001
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0137 0.0157
Toxoplasma gondii cathepsin CPL 0.0016 0.0021 0.0004
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0142 0.0682
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0315 0.1905
Echinococcus multilocularis snurportin 1 0.0302 0.5099 0.5382
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0897 0.0929
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0062 0.0829 0.5019
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0021 0.011 0.0121
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0203 0.0827
Schistosoma mansoni nephrin 0.0031 0.0276 0.0397
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0016 0.0021 0.003
Mycobacterium tuberculosis Conserved protein 0.0043 0.0507 0.1039
Echinococcus granulosus roundabout 2 0.0031 0.0276 0.0256
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0032 0.0059
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0547 0.9457 1
Brugia malayi Associated with TFs and helicases family protein 0.0023 0.0142 0.0163
Brugia malayi Cytochrome P450 family protein 0.0026 0.0192 0.0231
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0023 0.0142 0.0631
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0088 0.13 0.787
Schistosoma mansoni ran 0.0021 0.0103 0.0148
Brugia malayi ecdysteroid receptor 0.0019 0.0067 0.0062
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0016 0.0021 0.003
Echinococcus granulosus caspase 0.0027 0.0221 0.0201
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0155 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0723 0.3184
Schistosoma mansoni titin 0.0031 0.0276 0.0397
Giardia lamblia PHD finger protein 15 0.003 0.0269 0.1698
Echinococcus granulosus importin subunit beta 1 0.0028 0.0236 0.0216
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0026 0.0192 0.0967
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0507 0.1039
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0399 0.0402
Mycobacterium leprae Probable lipase LipE 0.0043 0.0507 0.0945
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.0251 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0021 0.0002
Leishmania major cathepsin L-like protease 0.0062 0.083 0.502
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0121
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0124 0.194 1
Schistosoma mansoni caspase-7 (C14 family) 0.0027 0.0221 0.0317
Loa Loa (eye worm) lectin C-type domain-containing protein 0.0021 0.011 0.0121
Onchocerca volvulus 0.0031 0.0276 0.0344
Onchocerca volvulus 0.0288 0.4851 0.6498
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0023 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0221 0.0907
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0047 0.0563 0.0575
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0021 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0221 0.027
Loa Loa (eye worm) projectin 0.0031 0.0276 0.0344
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0299 0.5046 0.7256
Schistosoma mansoni cpg binding protein 0.0029 0.024 0.0346
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0884 0.5351
Brugia malayi Cytochrome P450 family protein 0.0026 0.0192 0.0231
Echinococcus multilocularis thioredoxin glutathione reductase 0.0085 0.1236 0.1288
Onchocerca volvulus 0.0031 0.0276 0.0344
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0062 0.0089
Brugia malayi isocitrate dehydrogenase 0.0016 0.0023 0.0004
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0079 0.1131 0.1494
Onchocerca volvulus 0.0021 0.011 0.0121
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0141 0.0545
Leishmania major importin beta-1 subunit, putative 0.0023 0.0141 0.0853
Onchocerca volvulus Arrow homolog 0.0047 0.0562 0.0728
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0016 0.0021 0.003
Entamoeba histolytica cysteine protease, putative 0.0016 0.0021 0.0003
Echinococcus granulosus cubilin 0.0021 0.011 0.009
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1652 1
Treponema pallidum NADH oxidase 0.0029 0.0251 0.0751
Brugia malayi hypoxia-induced factor 1 0.0164 0.2654 0.3543
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0016 0.0021 0.003
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0026 0.0192 0.0967
Trypanosoma brucei Fibronectin type III domain containing protein, putative 0.0031 0.0276 0.1669
Loa Loa (eye worm) hypothetical protein 0.0043 0.0507 0.0654
Schistosoma mansoni RAR-like nuclear receptor 0.0019 0.0067 0.0096
Loa Loa (eye worm) CAMK protein kinase 0.0032 0.0295 0.037
Echinococcus granulosus pyruvate kinase 0.0017 0.0032 0.0011
Echinococcus granulosus Phosphotidylinositol phosphatase PTPRQ 0.0031 0.0276 0.0256
Loa Loa (eye worm) hypothetical protein 0.0016 0.0021 0.0001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0221 0.0907
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Onchocerca volvulus 0.0047 0.0562 0.0728
Onchocerca volvulus 0.0242 0.4039 0.5406
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0269 0.0249
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0444 0.0569
Echinococcus granulosus fibronectin type III domain-containing protein 0.0031 0.0276 0.0256
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0067 0.0062
Echinococcus multilocularis muscleblind protein 1 0.0146 0.2337 0.2455
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1482 0.6622
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0047 0.0563 0.081
Onchocerca volvulus 0.0031 0.0276 0.0344
Loa Loa (eye worm) hypothetical protein 0.0434 0.7455 1
Brugia malayi beta-lactamase 0.0043 0.0507 0.0654
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0137 0.0124
Echinococcus multilocularis cpg binding protein 0.0032 0.0303 0.0299
Onchocerca volvulus 0.0434 0.7455 1
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0027 0.0221 0.027
Onchocerca volvulus 0.0021 0.011 0.0121
Leishmania major cathepsin L-like protease 0.0016 0.0021 0.0127
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0016 0.0021 0.003
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0016 0.0021 0.003
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0047 0.0562 0.0728
Schistosoma mansoni protein tyrosine phosphatase 0.0047 0.0563 0.081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0021 0.0002
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0026 0.0192 0.0967
Plasmodium falciparum pyruvate kinase 0.0033 0.0315 0.1534
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0507 0.1039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0021 0.0002
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0099 0.1487 0.147
Brugia malayi Heterochromatin protein 1 0.014 0.2227 0.2969
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0276 0.0344
Brugia malayi Cathepsin L-like precursor 0.0016 0.0021 0.0001
Echinococcus multilocularis chromobox protein 1 0.014 0.2227 0.2339
Schistosoma mansoni hypothetical protein 0.0288 0.4851 0.6976
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0057 0.0741 0.1065
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0026 0.0192 0.0363
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0023 0.0142 0.0121
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0032 0.0064
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0067 0.0062
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0315 0.0396
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0023 0.0018
Onchocerca volvulus 0.0029 0.024 0.0296
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0137 0.0798
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0021 0.0127
Echinococcus granulosus cubilin 0.0021 0.011 0.009
Brugia malayi cytochrome P450 0.0026 0.0192 0.0231
Echinococcus granulosus neuroglian 0.0031 0.0276 0.0256
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.5099 0.6832
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0251 0.152
Schistosoma mansoni bromodomain containing protein 0.0064 0.0865 0.1244
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0047 0.0562 0.0574
Loa Loa (eye worm) hypothetical protein 0.0031 0.0276 0.0344
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0016 0.0021 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0221 0.0907
Brugia malayi Fibronectin type III domain containing protein 0.0031 0.0276 0.0344
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0067 0.0096
Brugia malayi 6-phosphofructokinase 0.0108 0.1652 0.2195
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0507 0.1039
Brugia malayi Protein cec-1. 0.0023 0.0142 0.0163
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0031 0.0276 0.0271
Echinococcus granulosus caspase 8 0.0027 0.0221 0.0201
Onchocerca volvulus 0.0057 0.0741 0.0969
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0021 0.0001
Trypanosoma cruzi metacaspase 5, putative 0.0027 0.0221 0.1336
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0047 0.0562 0.0728
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0026 0.0192 0.0967
Loa Loa (eye worm) hypothetical protein 0.0047 0.0562 0.0728
Leishmania major DNA polymerase kappa, putative 0.0017 0.0036 0.0217
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0023 0.0142 0.0128
Brugia malayi PHD-finger family protein 0.0026 0.0196 0.0237
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.1196 0.7241
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0315 0.1534
Echinococcus granulosus chromobox protein 1 0.014 0.2227 0.2212
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0221 0.0907
Trichomonas vaginalis chromobox protein, putative 0.0085 0.1238 0.5514
Loa Loa (eye worm) hypothetical protein 0.0146 0.2337 0.3117
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0021 0.011 0.0158
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0029 0.0251 0.152
Echinococcus granulosus neuropilin nrp and tolloid tll 0.0021 0.011 0.009
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.1652 0.2376
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0192 0.3142 0.6705
Onchocerca volvulus 0.0016 0.0021 0.0001
Onchocerca volvulus Serine\/threonine kinase homolog 0.0098 0.1482 0.1966
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0056 0.0734 0.4445
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0019 0.0067 0.0047
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0256 0.1068
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.1652 1
Trypanosoma brucei protein tyrosine phosphatase 1 0.0016 0.0021 0.0125
Plasmodium falciparum thioredoxin reductase 0.0084 0.1228 0.6287
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0019 0.0067 0.0062
Echinococcus granulosus dna polymerase kappa 0.0082 0.1196 0.1178
Echinococcus granulosus snurportin 1 0.0302 0.5099 0.5089
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0221 0.0907
Loa Loa (eye worm) hypothetical protein 0.0057 0.0741 0.0969
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0019 0.0067 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0019 0.0067 0.0062
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.1652 0.2376
Loa Loa (eye worm) fibroinase 0.0016 0.0021 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0019 0.0067 0.0062
Plasmodium vivax vivapain-2 0.0016 0.0021 0.0003
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0016 0.0021 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1482 0.6622
Onchocerca volvulus 0.0057 0.0741 0.0969
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0252 0.0101
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0029 0.0251 0.031
Onchocerca volvulus 0.0031 0.0276 0.0344
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.0251 0.152
Brugia malayi Lethal protein 805 0.0031 0.0276 0.0344
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0315 0.0396
Loa Loa (eye worm) glutathione reductase 0.0084 0.1228 0.1624
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0163
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0057 0.0741 0.0722
Leishmania major DNA polymerase eta, putative 0.0081 0.1176 0.7117
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0021 0.0001
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0026 0.0192 0.0967
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0016 0.0021 0.0125
Echinococcus granulosus Chromo domain 0.0023 0.0142 0.0121
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0103 0.0111
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0063 0.0846 0.5122
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0031 0.0276 0.0256
Onchocerca volvulus Protein ultraspiracle homolog 0.0019 0.0067 0.0062
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0026 0.0192 0.0967

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 4.7444 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.7865 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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