Detailed information for compound 1378254

Basic information

Technical information
  • TDR Targets ID: 1378254
  • Name: 3-(3-methylsulfanylphenyl)-1-[[3-[[(3-methyls ulfanylphenyl)carbamoylamino]methyl]phenyl]me thyl]urea
  • MW: 466.619 | Formula: C24H26N4O2S2
  • H donors: 4 H acceptors: 2 LogP: 3.94 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: CSc1cccc(c1)NC(=O)NCc1cccc(c1)CNC(=O)Nc1cccc(c1)SC
  • InChi: 1S/C24H26N4O2S2/c1-31-21-10-4-8-19(13-21)27-23(29)25-15-17-6-3-7-18(12-17)16-26-24(30)28-20-9-5-11-22(14-20)32-2/h3-14H,15-16H2,1-2H3,(H2,25,27,29)(H2,26,28,30)
  • InChiKey: HUJSVYPUNFORCF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 3-[3-(methylthio)phenyl]-1-[[3-[[[[[3-(methylthio)phenyl]amino]-oxomethyl]amino]methyl]phenyl]methyl]urea
  • 3-[3-(methylthio)phenyl]-1-[3-[[[3-(methylthio)phenyl]carbamoylamino]methyl]benzyl]urea
  • T5300246
  • MLS000334593
  • SMR000249351

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens bromodomain adjacent to zinc finger domain, 2B Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma japonicum Cleft lip and palate transmembrane protein 1-like protein, putative Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma mansoni bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma japonicum ko:K01549 ATP synthase [EC3.6.3.14], putative Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum expressed protein Get druggable targets OG5_131570 All targets in OG5_131570
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus granulosus bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Brugia malayi Bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus multilocularis bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Echinococcus multilocularis 0.0126 0.019 0.0218
Echinococcus granulosus myotubularin protein 13 0.0112 0.0123 0.0113
Brugia malayi casein kinase 1, delta 0.0239 0.0711 0.0771
Onchocerca volvulus 0.0231 0.0673 0.1277
Brugia malayi Protein kinase domain containing protein 0.0251 0.0767 0.0831
Brugia malayi serine/threonine kinase 12 0.032 0.1087 0.1179
Entamoeba histolytica serine/threonine kinase, putative 0.0104 0.0089 0.0176
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0218 0.0616 0.1053
Brugia malayi phosphoinositide-dependent protein kinase I 0.0179 0.0434 0.047
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0507 0.1952 0.2355
Plasmodium vivax serine/threonine protein kinase, putative 0.0183 0.045 0.3591
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0319 0.108 0.1298
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0261 0.0815 0.3433
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0224 0.0643 0.0634
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0104 0.0089 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0734 0.3003 0.326
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.0673 0.073
Loa Loa (eye worm) protein kinase domain-containing protein 0.0336 0.1159 0.1257
Loa Loa (eye worm) AUR protein kinase 0.032 0.1087 0.1179
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0126 0.019 0.0218
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Echinococcus granulosus casein kinase I delta 0.0239 0.0711 0.0702
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Entamoeba histolytica protein kinase, putative 0.032 0.1087 0.3065
Echinococcus multilocularis rac serine:threonine kinase 0.0364 0.1292 0.1554
Trichomonas vaginalis AGC family protein kinase 0.032 0.1087 0.4115
Trichomonas vaginalis protein kinase atn1, putative 0.0104 0.0089 0.0229
Echinococcus granulosus tyrosine protein kinase csk 0.0104 0.0089 0.0079
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Schistosoma mansoni protein kinase 0.0519 0.2009 0.3432
Schistosoma mansoni tensin-related 0.0126 0.019 0.0324
Plasmodium vivax serine/threonine protein kinase 6, putative 0.032 0.1087 0.9029
Entamoeba histolytica SH2 domain containing protein 0.0126 0.019 0.0467
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0104 0.0089 0.0229
Loa Loa (eye worm) TK/ROR protein kinase 0.0152 0.031 0.0336
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0776 0.32 0.3473
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0222 0.0631 0.0622
Loa Loa (eye worm) hypothetical protein 0.1322 0.5724 0.6213
Onchocerca volvulus 0.0126 0.019 0.0358
Toxoplasma gondii protein kinase domain-containing protein 0.0104 0.0089 0.0238
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0126 0.019 0.0205
Echinococcus granulosus tyrosine protein kinase 0.0633 0.2535 0.2528
Brugia malayi RhoGAP domain containing protein 0.0218 0.0616 0.0668
Echinococcus multilocularis protein kinase 0.0104 0.0089 0.0096
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0222 0.0631 0.5138
Entamoeba histolytica hypothetical protein 0.0105 0.0092 0.0185
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0156 0.0325 0.0383
Onchocerca volvulus 0.0104 0.0089 0.0167
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0126 0.019 0.0218
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0104 0.0089 0.0176
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0156 0.0325 0.0316
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0179 0.0434 0.047
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Echinococcus granulosus tyrosine protein kinase Src64B 0.0507 0.1952 0.1944
Schistosoma mansoni tensin 0.0126 0.019 0.0324
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0269 0.085 0.3192
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0195 0.0643
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0196 0.0515 0.1887
Entamoeba histolytica protein kinase domain containing protein 0.0283 0.0915 0.2568
Trichomonas vaginalis CAMK family protein kinase 0.0595 0.236 0.9073
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0901 0.3776 0.377
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.035 0.1226 0.4657
Trichomonas vaginalis AGC family protein kinase 0.0646 0.2598 1
Brugia malayi serine/threonine protein kinase 6 0.032 0.1087 0.1179
Echinococcus granulosus tyrosine protein kinase Fyn 0.0507 0.1952 0.1944
Schistosoma mansoni tyrosine kinase 0.0786 0.3246 0.5545
Schistosoma mansoni tyrosine kinase 0.0313 0.1054 0.1801
Loa Loa (eye worm) hypothetical protein 0.0315 0.1062 0.1153
Echinococcus multilocularis hemicentin 1 0.0088 0.0013 0.0004
Echinococcus granulosus tyrosine protein kinase Fyn 0.0507 0.1952 0.1944
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Echinococcus multilocularis mitogen activated protein kinase 11 0.035 0.1226 0.1475
Brugia malayi ephrin receptor 1 precursor 0.0171 0.0397 0.043
Loa Loa (eye worm) hypothetical protein 0.0272 0.0864 0.0938
Onchocerca volvulus 0.0087 0.0007 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Trichomonas vaginalis AGC family protein kinase 0.0646 0.2598 1
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trichomonas vaginalis AGC family protein kinase 0.032 0.1087 0.4115
Echinococcus multilocularis unc 13 (munc13) 0.0095 0.0045 0.0042
Echinococcus multilocularis activated cdc42 kinase 1 0.0104 0.0089 0.0096
Echinococcus multilocularis Glutaredoxin protein 5 0.0272 0.0867 0.1039
Trichomonas vaginalis CMGC family protein kinase 0.0444 0.1662 0.6357
Loa Loa (eye worm) hypothetical protein 0.0088 0.0013 0.0014
Schistosoma mansoni diacylglycerol kinase theta 0.0092 0.0032 0.0054
Brugia malayi protein unc-22 0.0154 0.032 0.0346
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Loa Loa (eye worm) hypothetical protein 0.0795 0.3285 0.3565
Schistosoma mansoni hypothetical protein 0.0225 0.0645 0.1101
Loa Loa (eye worm) hypothetical protein 0.0196 0.0515 0.0558
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0218 0.0616 0.0607
Schistosoma mansoni tyrosine kinase 0.0991 0.4195 0.7167
Onchocerca volvulus 0.0716 0.292 0.5544
Echinococcus multilocularis SH2 motif 0.0126 0.019 0.0218
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Loa Loa (eye worm) AUR protein kinase 0.032 0.1087 0.1179
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.0516 0.0881
Loa Loa (eye worm) AGC/PKA protein kinase 0.0248 0.0756 0.082
Echinococcus granulosus twitchin 0.0304 0.1011 0.1003
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Brugia malayi hypothetical protein 0.0218 0.0616 0.0668
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Entamoeba histolytica tyrosin kinase, putative 0.0104 0.0089 0.0176
Echinococcus granulosus epidermal growth factor receptor 0.0891 0.373 0.3724
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0248 0.0756 0.0904
Plasmodium falciparum serine/threonine protein kinase KIN 0.0196 0.0515 0.414
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0104 0.0089 0.0176
Plasmodium falciparum calcium-dependent protein kinase 5 0.0222 0.0631 0.5138
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Entamoeba histolytica hypothetical protein 0.0104 0.0089 0.0176
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0248 0.0756 0.3183
Trypanosoma brucei protein kinase, putative 0.0177 0.0423 0.1529
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Loa Loa (eye worm) TK protein kinase 0.0298 0.0986 0.107
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0756 0.1291
Echinococcus multilocularis expressed conserved protein 0.0296 0.0976 0.1171
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Trichomonas vaginalis CMGC family protein kinase 0.0444 0.1662 0.6357
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0152 0.031 0.0364
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Echinococcus multilocularis raf serine:threonine protein kinase 0.0197 0.0516 0.0613
Trichomonas vaginalis AGC family protein kinase 0.0179 0.0434 0.1572
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0104 0.0089 0.0096
Echinococcus granulosus serine:threonine protein kinase 3 0.0565 0.2223 0.2215
Trichomonas vaginalis CMGC family protein kinase 0.022 0.0624 0.2313
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0515 0.0879
Trichomonas vaginalis AGC family protein kinase 0.0104 0.0089 0.0229
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Entamoeba histolytica hypothetical protein, conserved 0.0104 0.0089 0.0176
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1026 0.4355 0.4349
Echinococcus granulosus tyrosine protein kinase otk 0.0088 0.0013 0.0004
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.0673 0.073
Leishmania major folate/biopterin transporter, putative 0.0092 0.003 0.0099
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0092 0.003 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.0978 0.1671
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0195 0.0643
Loa Loa (eye worm) TK protein kinase 0.0104 0.0089 0.0096
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0446 0.167 0.1812
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Onchocerca volvulus 0.0104 0.0089 0.0167
Schistosoma mansoni hypothetical protein 0.0104 0.0089 0.0152
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0195 0.0333
Loa Loa (eye worm) AUR protein kinase 0.032 0.1087 0.1179
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Loa Loa (eye worm) hypothetical protein 0.0184 0.0459 0.0498
Echinococcus multilocularis CDC7 cell division cycle 7 0.0444 0.1662 0.2004
Trichomonas vaginalis CMGC family protein kinase 0.022 0.0624 0.2313
Trichomonas vaginalis CMGC family protein kinase 0.0306 0.102 0.3857
Brugia malayi Egg laying defective protein 4 0.0296 0.0976 0.1058
Plasmodium vivax protein kinase Crk2 0.0261 0.0815 0.6703
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0988 0.4179 0.4536
Loa Loa (eye worm) TK protein kinase 0.0425 0.1571 0.1704
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Brugia malayi Protein kinase domain containing protein 0.0269 0.085 0.0921
Brugia malayi STE20-like kinase MST 0.0565 0.2223 0.2412
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.022 0.0624 0.0677
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Giardia lamblia Kinase, NEK 0.0299 0.0992 0.3974
Schistosoma mansoni protein tyrosine kinase 0.0104 0.0089 0.0152
Schistosoma mansoni tyrosine protein kinase 0.0104 0.0089 0.0152
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0283 0.0915 0.0906
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0515 0.0879
Echinococcus granulosus NDR protein kinase 0.0354 0.1245 0.1237
Onchocerca volvulus 0.0444 0.1662 0.3156
Trichomonas vaginalis CAMK family protein kinase 0.0595 0.236 0.9073
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0127 0.0195 0.0801
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0104 0.0089 0.0096
Entamoeba histolytica protein kinase, putative 0.0354 0.1245 0.3523
Echinococcus granulosus contactin 0.0123 0.0173 0.0164
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Echinococcus multilocularis neuroglian 0.0123 0.0173 0.0198
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0489 0.187 0.2255
Echinococcus multilocularis protein kinase c iota type 0.0629 0.2518 0.3041
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1322 0.5724 0.6213
Giardia lamblia Kinase, CMGC CK2 0.022 0.0624 0.2356
Loa Loa (eye worm) hypothetical protein 0.0306 0.1021 0.1108
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1089 0.4646 0.5621
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0092 0.003 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0089 0.0152
Schistosoma mansoni tyrosine kinase 0.0174 0.0409 0.0699
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0319 0.108 0.1071
Echinococcus granulosus Glutaredoxin protein 5 0.0272 0.0867 0.0858
Giardia lamblia Kinase, CMGC DYRK 0.0306 0.102 0.4102
Loa Loa (eye worm) TK/EGFR protein kinase 0.135 0.5853 0.6354
Plasmodium falciparum protein kinase, putative 0.0104 0.0089 0.0503
Echinococcus granulosus calcium dependent protein kinase 0.015 0.0298 0.0288
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0092 0.003 0.0099
Echinococcus multilocularis 0.0383 0.1377 0.1658
Echinococcus multilocularis insulin receptor 0.0991 0.4195 0.5074
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0104 0.0089 0.0176
Brugia malayi Immunoglobulin I-set domain containing protein 0.0088 0.0013 0.0013
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0507 0.1952 0.2355
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0899 0.3769 0.4557
Entamoeba histolytica tyrosin kinase, putative 0.0111 0.0121 0.027
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.054 0.2103 0.2283
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.3464 0.5917
Loa Loa (eye worm) TK/ABL protein kinase 0.0688 0.2789 0.3027
Schistosoma mansoni netrin receptor unc5 0.0104 0.0087 0.0148
Loa Loa (eye worm) hypothetical protein 0.0126 0.019 0.0205
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0745 0.3056 0.3317
Schistosoma mansoni tyrosine kinase 0.0575 0.2267 0.3873
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0092 0.003 0.0099
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Trichomonas vaginalis STE family protein kinase 0.0111 0.012 0.035
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0195 0.0507 0.0549
Echinococcus granulosus expressed protein 0.0183 0.045 0.0441
Echinococcus granulosus activated cdc42 kinase 1 0.0104 0.0089 0.0079
Brugia malayi Serine/threonine-protein kinase SULU 0.0489 0.187 0.2029
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Echinococcus granulosus tyrosine kinase 0.0104 0.0089 0.0079
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0186 0.0466 0.1268
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.3464 0.4187
Brugia malayi Tyrosine-protein kinase abl-1 0.0282 0.0912 0.0989
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.167 0.2853
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Entamoeba histolytica PH domain containing protein kinase, putative 0.0364 0.1292 0.3658
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0246 0.0745 0.2785
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0354 0.1245 0.1498
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0123 0.0173 0.0198
Loa Loa (eye worm) hypothetical protein 0.0795 0.3285 0.3565
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0111 0.012 0.035
Entamoeba histolytica protein kinase, putative 0.0222 0.0631 0.1746
Entamoeba histolytica hypothetical protein 0.0104 0.0089 0.0176
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0248 0.0756 0.3183
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.012 0.0205
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Echinococcus multilocularis protein kinase shaggy 0.0283 0.0915 0.1098
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0089 0.0229
Onchocerca volvulus 0.0104 0.0089 0.0167
Entamoeba histolytica serine/threonine protein kinase, putative 0.0595 0.236 0.675
Trichomonas vaginalis CK1 family protein kinase 0.0239 0.0711 0.2652
Brugia malayi hypothetical protein 0.0104 0.0089 0.0096
Echinococcus multilocularis protein kinase c eta type 0.0092 0.0032 0.0027
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0222 0.0631 0.0622
Loa Loa (eye worm) hypothetical protein 0.0272 0.0864 0.0938
Onchocerca volvulus 0.0126 0.019 0.0358
Schistosoma mansoni cell adhesion molecule 0.0088 0.0013 0.0023
Schistosoma mansoni protein kinase C mu 0.0092 0.0032 0.0054
Loa Loa (eye worm) TK protein kinase 0.0773 0.3184 0.3456
Echinococcus granulosus tensin 0.0126 0.019 0.018
Schistosoma mansoni vam6/vps39 related 0.0246 0.0745 0.1273
Echinococcus multilocularis Rac GTPase activating protein 1 0.0092 0.0032 0.0027
Echinococcus multilocularis Diacylglycerol kinase theta 0.0092 0.0032 0.0027
Entamoeba histolytica protein kinase 2, putative 0.0345 0.1201 0.3394
Loa Loa (eye worm) serine/threonine protein kinase 0.0104 0.0089 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0815 0.1392
Giardia lamblia Kinase, CMGC CDK 0.0261 0.0815 0.3196
Loa Loa (eye worm) hypothetical protein 0.0104 0.0089 0.0096
Echinococcus multilocularis dual specificity 0.0306 0.102 0.1225
Echinococcus multilocularis dual specificity 0.0306 0.102 0.1225
Brugia malayi tRNA modification GTPase TrmE family protein 0.0126 0.019 0.0205
Brugia malayi MAP kinase sur-1 0.0127 0.0195 0.0211
Trichomonas vaginalis AGC family protein kinase 0.0646 0.2598 1
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0104 0.0089 0.0229
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0179 0.0434 0.0425
Trichomonas vaginalis STE family protein kinase 0.0141 0.0259 0.0891
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0511 0.1971 0.1964
Brugia malayi Ras association domain family 1 isoform A 0.0092 0.0032 0.0034
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0306 0.102 0.4308
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0507 0.1952 0.2355
Leishmania major protein kinase, putative 0.0177 0.0423 0.1767
Entamoeba histolytica ankyrin repeat protein 0.0104 0.0089 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.012 0.035
Loa Loa (eye worm) hypothetical protein 0.0246 0.0745 0.0808
Schistosoma mansoni serine/threonine protein kinase 0.0361 0.1277 0.2181
Brugia malayi Protein kinase domain containing protein 0.0261 0.0815 0.0883
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0246 0.0745 0.1273
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0541 0.2112 0.2104
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0127 0.0195 0.0643
Trichomonas vaginalis CMGC family protein kinase 0.022 0.0624 0.2313
Trypanosoma brucei Pseudokinase, putative 0.0104 0.0089 0.0229
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0776 0.32 0.3867
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0126 0.019 0.0205
Echinococcus multilocularis mitogen activated protein kinase 3 0.0127 0.0195 0.0225
Leishmania major protein kinase, putative 0.0104 0.0089 0.0349
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0409 0.1498 0.1805
Giardia lamblia Kinase, PLK 0.0595 0.236 1
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0092 0.003 0.0099
Echinococcus multilocularis dual specificity 0.0269 0.085 0.1018
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0868 0.3624 0.4382
Onchocerca volvulus 0.0091 0.0028 0.0052
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0261 0.0815 0.3168
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Echinococcus granulosus nervana 2 0.0272 0.0867 0.0858
Echinococcus granulosus tyrosine protein kinase Srms 0.1129 0.4833 0.4828
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Trichomonas vaginalis protein tyrosine kinase, putative 0.0104 0.0089 0.0229
Echinococcus granulosus protein kinase C gamma type 0.0444 0.1663 0.1654
Echinococcus granulosus natriuretic peptide receptor 1 0.0104 0.0089 0.0079
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0475 0.1806 0.2178
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0126 0.019 0.0218
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0248 0.0756 0.62
Echinococcus multilocularis titin 0.0154 0.032 0.0376
Echinococcus granulosus Protein kinase C brain isozyme 0.0537 0.2089 0.2082
Loa Loa (eye worm) AGC/PKA protein kinase 0.0248 0.0756 0.082
Echinococcus multilocularis receptor type guanylyl cyclase 0.0104 0.0089 0.0096
Trypanosoma cruzi casein kinase II, putative 0.022 0.0624 0.2623
Echinococcus multilocularis activin receptor type 0.0177 0.0423 0.0501
Echinococcus multilocularis Immunoglobulin 0.0184 0.0456 0.0541
Onchocerca volvulus Netrin receptor homolog 0.0112 0.0122 0.0229
Schistosoma mansoni SH2A 0.0126 0.019 0.0324
Onchocerca volvulus 0.0167 0.0377 0.0715
Brugia malayi SH2 domain containing protein 0.0126 0.019 0.0205
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0387 0.1396 0.1515
Schistosoma mansoni serine/threonine protein kinase 0.0517 0.2 0.3417
Onchocerca volvulus 0.0231 0.0673 0.1277
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.012 0.016 0.0173
Plasmodium falciparum NIMA related kinase 2 0.0111 0.012 0.0769
Loa Loa (eye worm) RGC/RGC protein kinase 0.0104 0.0089 0.0096
Entamoeba histolytica protein kinase, putative 0.032 0.1087 0.3065
Loa Loa (eye worm) SRC-1 0.0507 0.1952 0.2118
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Echinococcus granulosus neuroglian 0.0123 0.0173 0.0164
Entamoeba histolytica protein kinase, putative 0.0161 0.035 0.0932
Plasmodium falciparum glycogen synthase kinase 3 0.0283 0.0915 0.7563
Onchocerca volvulus 0.0104 0.0089 0.0167
Brugia malayi protein kinase C3,putative 0.0347 0.1211 0.1314
Schistosoma mansoni ephrin receptor 0.0139 0.0249 0.0425
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0104 0.0089 0.0152
Giardia lamblia Protein 21.1 0.0104 0.0089 0.000000030784
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0162 0.0356 0.0386
Onchocerca volvulus 0.0231 0.0673 0.1277
Brugia malayi Protein kinase domain containing protein 0.0136 0.0234 0.0253
Brugia malayi STAT protein, DNA binding domain containing protein 0.0126 0.019 0.0205
Onchocerca volvulus 0.0126 0.019 0.0358
Echinococcus granulosus suppressor of cytokine signaling 7 0.0126 0.019 0.018
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0424 0.157 0.1703
Brugia malayi hypothetical protein 0.0489 0.187 0.2029
Echinococcus granulosus tyrosine protein kinase shark 0.0701 0.2852 0.2845
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0507 0.1952 0.2355
Loa Loa (eye worm) CAMK protein kinase 0.0154 0.032 0.0347
Echinococcus granulosus signal transduction protein lnk realted 0.0126 0.019 0.018
Echinococcus multilocularis epidermal growth factor receptor 0.0891 0.373 0.451
Echinococcus multilocularis serine:threonine protein kinase 0.0251 0.0767 0.0918
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Giardia lamblia Kinase, CDC7 0.0444 0.1662 0.6929
Trypanosoma cruzi protein kinase, putative 0.0104 0.0089 0.0349
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0239 0.0711 0.2993
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Echinococcus granulosus SH2 domain containing protein 7 0.0126 0.019 0.018
Trypanosoma brucei protein kinase, putative 0.0127 0.0195 0.0643
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0177 0.0423 0.1585
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0269 0.085 0.3582
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0361 0.1277 0.1385
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0519 0.2009 0.2424
Brugia malayi Protein kinase domain containing protein 0.0991 0.4195 0.4553
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0156 0.0325 0.0316
Echinococcus granulosus hypothetical protein 0.0126 0.019 0.018
Echinococcus granulosus tyrosine protein kinase HCK 0.0298 0.0986 0.0978
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0127 0.0195 0.0801
Trichomonas vaginalis CMGC family protein kinase 0.0338 0.117 0.4439
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0479 0.1823 0.1978
Plasmodium falciparum casein kinase 2, alpha subunit 0.022 0.0624 0.5074
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0123 0.0173 0.0164
Echinococcus granulosus titin 0.0154 0.032 0.0311
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0198 0.0523 0.1433
Schistosoma mansoni protein kinase 0.0104 0.0089 0.0152
Brugia malayi protein kinase C II. 0.0449 0.1685 0.1828
Entamoeba histolytica protein kinase, putative 0.0646 0.2598 0.7439
Echinococcus granulosus protein kinase 0.0104 0.0089 0.0079
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0868 0.3624 0.3618
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0776 0.32 0.6075
Echinococcus multilocularis tyrosine kinase 0.0104 0.0089 0.0096
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0115 0.0135 0.041
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0507 0.1952 0.2355
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Schistosoma mansoni serine/threonine kinase 0.0354 0.1245 0.2127
Schistosoma mansoni protein kinase 0.0104 0.0089 0.0152
Trichomonas vaginalis STE family protein kinase 0.0186 0.0466 0.1699
Schistosoma mansoni tyrosine kinase 0.0313 0.1054 0.1801
Leishmania major protein kinase A catalytic subunit isoform 2 0.0248 0.0756 0.3183
Brugia malayi SH2 domain containing protein 0.0126 0.019 0.0205
Echinococcus multilocularis protein kinase 0.0104 0.0089 0.0096
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0179 0.0434 0.0741
Plasmodium vivax tyrosine kinase-like protein, putative 0.0104 0.0089 0.0503
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Giardia lamblia Kinase, CMGC GSK 0.0283 0.0915 0.3639
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0126 0.019 0.018
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Toxoplasma gondii aurora kinase 0.032 0.1087 0.4267
Echinococcus granulosus serine:threonine protein kinase N2 0.0286 0.0928 0.0919
Loa Loa (eye worm) SH2 domain-containing protein 0.0126 0.019 0.0205
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0088 0.0013 0.0023
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0104 0.0089 0.0152
Loa Loa (eye worm) hypothetical protein 0.0315 0.1062 0.1153
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Entamoeba histolytica ankyrin repeat protein 0.0104 0.0089 0.0176
Onchocerca volvulus Serine\/threonine kinase homolog 0.0595 0.236 0.4481
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0519 0.2009 0.2001
Schistosoma mansoni GTPase activating protein 0.0126 0.019 0.0324
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0104 0.0089 0.0176
Plasmodium vivax casein kinase 1, putative 0.0239 0.0711 0.5819
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0189 0.048 0.0471
Loa Loa (eye worm) hypothetical protein 0.0197 0.0516 0.056
Schistosoma mansoni nck2/grb4 0.0209 0.0571 0.0975
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0089 0.0096
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0089 0.0096
Entamoeba histolytica protein kinase , putative 0.032 0.1087 0.3065
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0253 0.0777 0.0768
Schistosoma mansoni serine/threonine protein kinase 0.0776 0.32 0.5466
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0734 0.3003 0.3259
Echinococcus multilocularis tyrosine protein kinase csk 0.0104 0.0089 0.0096
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0189 0.048 0.0471
Brugia malayi Variant SH3 domain containing protein 0.0209 0.0571 0.0619
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.012 0.035
Loa Loa (eye worm) hypothetical protein 0.0092 0.0032 0.0034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0104 0.0087 0.0093
Echinococcus multilocularis growth factor receptor bound protein 2 0.0209 0.0571 0.068
Schistosoma mansoni protein kinase 0.0104 0.0089 0.0152
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0338 0.117 0.127
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0345 0.1201 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0177 0.0423 0.1767
Loa Loa (eye worm) hypothetical protein 0.0316 0.107 0.1161
Schistosoma mansoni protein kinase 0.0104 0.0089 0.0152
Schistosoma mansoni serine/threonine protein kinase 0.064 0.2568 0.4387
Loa Loa (eye worm) hypothetical protein 0.0092 0.0032 0.0034
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0261 0.0815 0.0884
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0956 0.4029 0.4874
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0627 0.2507 0.2721
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0095 0.0044 0.0055
Echinococcus granulosus CDC7 cell division cycle 7 0.0444 0.1662 0.1654
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0104 0.0089 0.0096
Echinococcus multilocularis rho associated protein kinase 0.0716 0.292 0.3528
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0306 0.102 0.1107
Echinococcus multilocularis twitchin 0.012 0.016 0.0183
Brugia malayi Variant SH3 domain containing protein 0.0218 0.0616 0.0668
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0089 0.0096
Schistosoma mansoni hypothetical protein 0.0205 0.0553 0.0944
Plasmodium falciparum protein serine/threonine kinase-1 0.0338 0.117 0.974
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.0978 0.1671
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0196 0.0515 0.2159
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0109 0.0109 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0089 0.0152
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.0673 0.073
Trichomonas vaginalis STE family protein kinase 0.0299 0.0992 0.3744
Brugia malayi serine/threonine-protein kinase plk-2 0.0595 0.236 0.2561
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0595 0.236 0.9073
Loa Loa (eye worm) hypothetical protein 0.0126 0.019 0.0205
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0104 0.0089 0.0176
Plasmodium falciparum calcium-dependent protein kinase 1 0.0222 0.0631 0.5138
Brugia malayi Variant SH3 domain containing protein 0.0149 0.0294 0.0318
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0269 0.085 0.0922
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.0561 0.2204 0.3766
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Echinococcus multilocularis FL cytokine receptor 0.0104 0.0089 0.0096
Echinococcus granulosus c-Jun N-terminal kinases 0.0582 0.2299 0.2291
Loa Loa (eye worm) hypothetical protein 0.0095 0.0045 0.0048
Brugia malayi protein-tyrosine kinase 0.0425 0.1571 0.1704
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0507 0.1952 0.1944
Echinococcus granulosus dual specificity 0.0306 0.102 0.1012
Onchocerca volvulus 0.0159 0.0341 0.0645
Echinococcus multilocularis aurora kinase A 0.032 0.1087 0.1306
Brugia malayi Doublecortin family protein 0.0332 0.1141 0.1238
Loa Loa (eye worm) TK/EPH protein kinase 0.0284 0.0921 0.0999
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.036 0.1273 0.1382
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0425 0.1571 0.1562
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0442 0.165 0.1642
Echinococcus granulosus retinal guanylyl cyclase 2 0.0104 0.0089 0.0079
Echinococcus granulosus titin 0.0154 0.032 0.0311
Schistosoma mansoni hypothetical protein 0.0126 0.019 0.0324
Onchocerca volvulus 0.0126 0.019 0.0358
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0092 0.003 0.0099
Echinococcus multilocularis 0.0337 0.1165 0.1401
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0299 0.0992 0.8215
Toxoplasma gondii casein kinase I 0.0239 0.0711 0.275
Loa Loa (eye worm) TK protein kinase 0.0104 0.0089 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0089 0.0229
Entamoeba histolytica hypothetical protein 0.0105 0.0092 0.0185
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.0673 0.073
Brugia malayi Fibronectin type III domain containing protein 0.0218 0.0616 0.0668
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.032 0.0346
Trichomonas vaginalis STE family protein kinase 0.0189 0.048 0.1753
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Brugia malayi diacylglycerol kinase 0.0092 0.0032 0.0034
Loa Loa (eye worm) hypothetical protein 0.0246 0.0745 0.0808
Trichomonas vaginalis AGC family protein kinase 0.0179 0.0434 0.1572
Trypanosoma cruzi protein kinase, putative 0.0104 0.0089 0.0349
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0248 0.0756 0.2826
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Echinococcus granulosus dual specificity 0.0269 0.085 0.0841
Entamoeba histolytica serine/threonine kinase, putative 0.0104 0.0089 0.0176
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Entamoeba histolytica protein kinase, putative 0.0189 0.048 0.1308
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Echinococcus granulosus tyrosine protein kinase Lyn 0.0579 0.2286 0.2278
Echinococcus multilocularis N chimaerin 0.0218 0.0616 0.0735
Giardia lamblia Kinase, STE STE20 0.0186 0.0466 0.1662
Brugia malayi cytokine inducible SH2-containing protein 5 0.0126 0.019 0.0205
Trichomonas vaginalis CMGC family protein kinase 0.0306 0.102 0.3857
Trichomonas vaginalis CAMK family protein kinase 0.0278 0.0892 0.3356
Schistosoma mansoni protein kinase C 0.0095 0.0045 0.0076
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0283 0.0915 0.0993
Echinococcus multilocularis tyrosine protein kinase otk 0.0088 0.0013 0.0004
Loa Loa (eye worm) hypothetical protein 0.0104 0.0089 0.0096
Echinococcus multilocularis tyrosine protein kinase csk 0.0104 0.0089 0.0096
Giardia lamblia Kinase, CMGC SRPK 0.0183 0.045 0.1592
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0231 0.0673 0.1867
Entamoeba histolytica protein kinase, putative 0.0269 0.085 0.2378
Schistosoma mansoni serine/threonine protein kinase 0.0296 0.0976 0.1667
Entamoeba histolytica protein kinase, putative 0.0179 0.0434 0.1174
Schistosoma mansoni dynamin-associated protein 0.0087 0.0007 0.0012
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Brugia malayi Casein kinase II, alpha chain 0.022 0.0624 0.0676
Entamoeba histolytica casein kinase 1, putative 0.0239 0.0711 0.1977
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0338 0.117 0.4943
Giardia lamblia Kinase, STE STE20 0.0189 0.048 0.1722
Leishmania major serine/threonine-protein kinase a, putative 0.0092 0.003 0.0099
Giardia lamblia Kinase, CAMK CAMKL 0.0196 0.0515 0.1875
Loa Loa (eye worm) hypothetical protein 0.0104 0.0089 0.0096
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0104 0.0089 0.0096
Schistosoma mansoni ste20-related kinase 0.0451 0.1695 0.2896
Schistosoma mansoni serine/threonine protein kinase 0.0537 0.2089 0.3569
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0091 0.0028 0.003
Loa Loa (eye worm) casein kinase 0.0263 0.0825 0.0895
Onchocerca volvulus Tyrosine kinase homolog 0.1223 0.5266 1
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0246 0.0745 0.3138
Trichomonas vaginalis CAMK family protein kinase 0.0253 0.0777 0.2908
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0507 0.1952 0.1944
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Plasmodium vivax protein kinase, putative 0.0138 0.0243 0.1818
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.0769 0.0834
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0089 0.0096
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Brugia malayi cell division control protein 2 homolog 0.0261 0.0815 0.0883
Trypanosoma brucei rac serine-threonine kinase, putative 0.0646 0.2598 1
Echinococcus granulosus protein kinase 0.0337 0.1165 0.1156
Onchocerca volvulus 0.0104 0.0089 0.0167
Echinococcus granulosus cyclin dependent kinase 0.0261 0.0815 0.0806
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0115 0.0135 0.041
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0222 0.0631 0.0685
Entamoeba histolytica hypothetical protein 0.0104 0.0089 0.0176
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0345 0.1201 0.1444
Brugia malayi Peroxidasin 0.0089 0.0016 0.0017
Loa Loa (eye worm) protein kinase domain-containing protein 0.0104 0.0089 0.0096
Loa Loa (eye worm) hypothetical protein 0.0306 0.1021 0.1108
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0189 0.048 0.0471
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0306 0.102 0.3999
Echinococcus granulosus cGMP dependent protein kinase 1 0.0296 0.0976 0.0967
Toxoplasma gondii CMGC kinase, CK2 family 0.022 0.0624 0.2398
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0239 0.0711 0.0771
Brugia malayi Protein kinase domain 0.0189 0.048 0.052
Loa Loa (eye worm) AGC/PKG protein kinase 0.0296 0.0976 0.1059
Brugia malayi intracellular kinase 0.0283 0.0915 0.0993
Brugia malayi Protein kinase domain containing protein 0.0354 0.1245 0.1351
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Echinococcus multilocularis cyclin dependent kinase 0.0261 0.0815 0.0976
Brugia malayi Protein kinase c protein 2 0.0254 0.0783 0.0849
Echinococcus multilocularis mitogen activated protein kinase 14 0.035 0.1226 0.1475
Echinococcus granulosus retinal guanylyl cyclase 2 0.0104 0.0089 0.0079
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0283 0.0915 0.1564
Echinococcus granulosus casein kinase I alpha 0.0239 0.0711 0.0702
Echinococcus multilocularis serine:threonine protein kinase N2 0.0286 0.0928 0.1113
Schistosoma mansoni tyrosine kinase 0.0541 0.2112 0.3607
Echinococcus multilocularis calcium dependent protein kinase 0.015 0.0298 0.0349
Loa Loa (eye worm) hypothetical protein 0.0104 0.0089 0.0096
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0253 0.0777 0.093
Onchocerca volvulus 0.0104 0.0089 0.0167
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0767 0.2869
Onchocerca volvulus 0.0231 0.0673 0.1277
Loa Loa (eye worm) hypothetical protein 0.0088 0.0013 0.0014
Echinococcus granulosus casein kinase ii subunit alpha 0.022 0.0624 0.0615
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0296 0.0976 0.1171
Brugia malayi serine/threonine-protein kinase PAK 7 0.0511 0.197 0.2138
Plasmodium vivax unspecified product 0.022 0.0624 0.5074
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0899 0.3769 0.3762
Entamoeba histolytica protein kinase domain containing protein 0.0269 0.085 0.2378
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0283 0.0915 0.3861
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.035 0.1226 0.5181
Echinococcus multilocularis tyrosine protein kinase shark 0.0701 0.2852 0.3446
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Trypanosoma cruzi casein kinase, putative 0.0239 0.0711 0.2993
Echinococcus granulosus protein kinase c iota type 0.0629 0.2518 0.251
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0582 0.2299 0.2775
Loa Loa (eye worm) hypothetical protein 0.0092 0.0032 0.0034
Loa Loa (eye worm) hypothetical protein 0.0088 0.0013 0.0014
Schistosoma mansoni unc-13 (munc13) 0.0095 0.0045 0.0076
Schistosoma mansoni protein kinase 0.022 0.0624 0.1066
Echinococcus granulosus fch and double sh3 domains protein 2 0.0091 0.0028 0.0019
Brugia malayi Variant SH3 domain containing protein 0.0209 0.0571 0.0619
Toxoplasma gondii histone kinase SNF1, putative 0.0196 0.0515 0.1957
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0306 0.102 0.3857
Echinococcus multilocularis hypothetical protein 0.0225 0.0645 0.077
Echinococcus multilocularis death associated protein kinase 1 0.1869 0.8258 1
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0196 0.0515 0.2159
Brugia malayi RhoGEF domain containing protein 0.0092 0.0032 0.0034
Loa Loa (eye worm) TK/CSK protein kinase 0.0104 0.0089 0.0096
Echinococcus granulosus raf serine:threonine protein kinase 0.0197 0.0516 0.0506
Echinococcus granulosus mitogen activated protein kinase 0.0127 0.0195 0.0186
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0209 0.0571 0.0975
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Trichomonas vaginalis AGC family protein kinase 0.0646 0.2598 1
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.032 0.1087 0.3065
Leishmania major protein kinase, putative 0.0111 0.012 0.0481
Brugia malayi Protein kinase domain containing protein 0.0362 0.1283 0.1392
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0105 0.0092 0.0185
Echinococcus multilocularis mitogen activated protein kinase 0.0127 0.0195 0.0225
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0111 0.012 0.0769
Trypanosoma cruzi casein kinase, putative 0.0239 0.0711 0.2993
Echinococcus multilocularis dual specificity 0.0306 0.102 0.1225
Loa Loa (eye worm) hypothetical protein 0.0248 0.0756 0.082
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0195 0.0643
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0189 0.048 0.057
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Schistosoma mansoni adapter molecule crk 0.0209 0.0571 0.0975
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0595 0.236 0.2561
Loa Loa (eye worm) TK/Met protein kinase 0.0104 0.0089 0.0096
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0126 0.019 0.018
Schistosoma mansoni tyrosine kinase 0.0507 0.1952 0.3335
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0475 0.1806 0.1798
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0248 0.0756 0.62
Loa Loa (eye worm) hypothetical protein 0.0126 0.019 0.0205
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0272 0.0867 0.0858
Echinococcus granulosus kinase suppressor of Ras 1 0.0104 0.0089 0.0079
Brugia malayi Protein kinase domain containing protein 0.0988 0.4179 0.4535
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0222 0.0631 0.2342
Echinococcus granulosus Diacylglycerol kinase theta 0.0092 0.0032 0.0022
Loa Loa (eye worm) hypothetical protein 0.0104 0.0089 0.0096
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0186 0.0466 0.1699
Echinococcus granulosus cGMP dependent protein kinase 1 0.0296 0.0976 0.0967
Echinococcus granulosus intersectin 2 0.009 0.002 0.001
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0104 0.0089 0.0096
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0104 0.0089 0.0096
Schistosoma mansoni hypothetical protein 0.0205 0.0553 0.0944
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Echinococcus granulosus protein kinase c epsilon type 0.0449 0.1685 0.1677
Schistosoma mansoni serine/threonine protein kinase 0.012 0.016 0.0274
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0104 0.0089 0.0096
Brugia malayi Protein kinase domain containing protein 0.0377 0.1351 0.1465
Entamoeba histolytica hypothetical protein 0.0104 0.0089 0.0176
Loa Loa (eye worm) AGC/PKN protein kinase 0.064 0.2568 0.2787
Trichomonas vaginalis set domain proteins, putative 0.0286 0.093 0.3503
Entamoeba histolytica protein kinase domain containing protein 0.0177 0.0423 0.1142
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0104 0.0089 0.0096
Loa Loa (eye worm) hypothetical protein 0.0088 0.0013 0.0014
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0104 0.0089 0.0079
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0582 0.2299 0.2495
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.012 0.035
Trypanosoma brucei cdc2-related kinase 3 0.0261 0.0815 0.3055
Echinococcus multilocularis kinase suppressor of Ras 1 0.0104 0.0089 0.0096
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0332 0.1141 0.1238
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0537 0.2089 0.2521
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0127 0.0195 0.0667
Schistosoma mansoni serine/threonine protein kinase 0.0449 0.1685 0.2878
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0277 0.0888 0.3746
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0364 0.1292 0.5461
Echinococcus granulosus casein kinase I gamma 0.0336 0.1159 0.115
Toxoplasma gondii STE kinase 0.0104 0.0089 0.0238
Schistosoma mansoni hypothetical protein 0.0126 0.019 0.0324
Echinococcus multilocularis intersectin 2 0.009 0.002 0.0012
Leishmania major protein kinase, putative 0.0186 0.0466 0.1953
Brugia malayi Protein kinase domain containing protein 0.0442 0.1651 0.1791
Trichomonas vaginalis AGC family protein kinase 0.0299 0.0992 0.3744
Loa Loa (eye worm) hypothetical protein 0.018 0.0436 0.0473
Loa Loa (eye worm) hypothetical protein 0.0266 0.0836 0.0907
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Echinococcus multilocularis SH2 motif 0.0126 0.019 0.0218
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0104 0.0089 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0541 0.2112 0.2548
Echinococcus multilocularis expressed protein 0.0183 0.045 0.0534
Trichomonas vaginalis CMGC family protein kinase 0.0306 0.102 0.3857
Loa Loa (eye worm) TK/ACK protein kinase 0.0104 0.0089 0.0096
Echinococcus granulosus cyclin dependent kinase 1 0.0261 0.0815 0.0806
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0248 0.0756 0.0747
Brugia malayi Immunoglobulin I-set domain containing protein 0.0088 0.0013 0.0013
Echinococcus multilocularis tyrosine protein kinase csk 0.0104 0.0089 0.0096
Trypanosoma cruzi cdc2-related kinase 3 0.0261 0.0815 0.3433
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0318 0.1079 0.1296
Loa Loa (eye worm) hypothetical protein 0.1017 0.4313 0.4681
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0248 0.0756 0.0904
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0776 0.32 0.3193
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0104 0.0089 0.0176
Trichomonas vaginalis AGC family protein kinase 0.0377 0.1351 0.5142
Schistosoma mansoni serine/threonine protein kinase 0.0338 0.117 0.1999
Leishmania major protein kinase A catalytic subunit isoform 1 0.0248 0.0756 0.3183
Schistosoma mansoni protein kinase 0.0808 0.3344 0.5713
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Entamoeba histolytica protein kinase domain containing protein 0.0283 0.0915 0.2568
Loa Loa (eye worm) TK/RYK protein kinase 0.0104 0.0089 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.0673 0.073
Echinococcus multilocularis SHC transforming protein 3 0.0126 0.019 0.0218
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.012 0.016 0.0173
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0156 0.0325 0.0383
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0565 0.2223 0.2412
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0248 0.0756 0.2826
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.032 0.1087 0.1306
Echinococcus granulosus epidermal growth factor receptor 0.135 0.5853 0.5849
Echinococcus granulosus ephrin type A receptor 4 A 0.0246 0.0742 0.0733
Schistosoma mansoni serine/threonine protein kinase 0.0475 0.1806 0.3086
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0111 0.012 0.035
Echinococcus multilocularis protein kinase c epsilon type 0.0449 0.1685 0.2031
Echinococcus granulosus serine threonine protein kinase nrc 0.0345 0.1201 0.1192
Leishmania major casein kinase, putative 0.0239 0.0711 0.2993
Entamoeba histolytica p21-activated kinase 0.0209 0.0571 0.1572
Echinococcus multilocularis mitogen activated protein kinase 14 0.035 0.1226 0.1475
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Loa Loa (eye worm) hypothetical protein 0.0189 0.0481 0.0521
Echinococcus multilocularis heat shock protein 70 0.0104 0.0089 0.0096
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0104 0.0089 0.0096
Brugia malayi MH2 domain containing protein 0.0144 0.0273 0.0295
Trypanosoma brucei SNF1-related protein kinases, putative 0.0196 0.0515 0.1887
Trichomonas vaginalis AGC family protein kinase 0.0646 0.2598 1
Echinococcus granulosus insulin receptor 0.0991 0.4195 0.4189
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0095 0.0044 0.0055
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1322 0.5724 0.6213
Echinococcus granulosus cGMP dependent protein kinase 0.0296 0.0976 0.0967
Entamoeba histolytica protein kinase, putative 0.0627 0.2507 0.7175
Schistosoma mansoni serine/threonine protein kinase 0.0595 0.236 0.4032
Schistosoma mansoni vav2 0.0238 0.0707 0.1209
Trypanosoma cruzi NIMA-related kinase, putative 0.0092 0.003 0.0099
Brugia malayi C1-like domain containing protein 0.0479 0.1823 0.1978
Onchocerca volvulus 0.0315 0.1062 0.2016
Echinococcus multilocularis neuroglian 0.0232 0.0678 0.081
Brugia malayi Immunoglobulin I-set domain containing protein 0.0088 0.0013 0.0013
Brugia malayi Protein kinase domain containing protein 0.0426 0.1579 0.1713
Onchocerca volvulus 0.0154 0.032 0.0606
Trichomonas vaginalis CAMK family protein kinase 0.0478 0.1816 0.6955
Entamoeba histolytica protein kinase, putative 0.0156 0.0325 0.086
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Schistosoma mansoni tyrosine kinase 0.0562 0.2205 0.3767
Echinococcus granulosus tyrosine protein kinase ABL1 0.0688 0.2789 0.2782
Leishmania major protein kinase, putative 0.0092 0.003 0.0099
Entamoeba histolytica casein kinase, putative 0.0239 0.0711 0.1977
Brugia malayi Protein kinase domain containing protein 0.0646 0.2598 0.2819
Schistosoma mansoni tyrosine kinase 0.0786 0.3246 0.5545
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0901 0.3776 0.4566
Entamoeba histolytica protein kinase, putative 0.0092 0.003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0126 0.019 0.0205
Brugia malayi Protein kinase domain containing protein 0.0808 0.3344 0.363
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Brugia malayi hypothetical protein 0.0126 0.019 0.0205
Echinococcus granulosus tyrosine kinase 0.0231 0.0673 0.0664
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0442 0.165 0.1989
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0808 0.3344 0.4043
Echinococcus multilocularis hemicentin 1 0.0088 0.0013 0.0004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0088 0.0013 0.0013
Entamoeba histolytica PH domain containing protein kinase, putative 0.0364 0.1292 0.3658
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Leishmania major protein kinase, putative 0.0338 0.117 0.4943
Entamoeba histolytica protein kinase, putative 0.0156 0.0325 0.086
Schistosoma mansoni protein kinase 0.0424 0.157 0.2682
Brugia malayi Protein kinase domain containing protein 0.0338 0.117 0.1269
Echinococcus granulosus tyrosine kinase 0.0425 0.1571 0.1562
Loa Loa (eye worm) hypothetical protein 0.0262 0.0819 0.0888
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0222 0.0631 0.0754
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0261 0.0815 0.0806
Loa Loa (eye worm) hypothetical protein 0.0218 0.0616 0.0668
Trichomonas vaginalis TKL family protein kinase 0.0106 0.0095 0.0252
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.032 0.1087 0.3065
Plasmodium falciparum serine/threonine protein kinase 0.0183 0.045 0.3591
Schistosoma mansoni serine/threonine kinase 0.0478 0.1816 0.3103
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0179 0.0434 0.0514
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0178 0.0429 0.1611
Echinococcus granulosus growth factor receptor bound protein 2 0.0213 0.0591 0.0582
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0095 0.0045 0.0042
Brugia malayi Immunoglobulin I-set domain containing protein 0.0123 0.0173 0.0187
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0104 0.0089 0.0176
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1026 0.4355 0.5268
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0283 0.0915 0.0993
Echinococcus multilocularis casein kinase I alpha 0.0239 0.0711 0.085
Echinococcus multilocularis serine:threonine protein kinase 0.0251 0.0767 0.0918
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0246 0.0745 0.0736
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Loa Loa (eye worm) raf kinase 0.0092 0.0032 0.0034
Echinococcus granulosus activated cdc42 kinase 1 0.0104 0.0089 0.0079
Echinococcus multilocularis roundabout 2 0.0123 0.0173 0.0198
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0595 0.236 0.2849
Schistosoma mansoni serine/threonine protein kinase 0.0442 0.1651 0.282
Brugia malayi Kinase associated domain 1 family protein 0.0225 0.0645 0.0699
Trichomonas vaginalis CAMK family protein kinase 0.0595 0.236 0.9073
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0104 0.0089 0.0152
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0104 0.0089 0.0238
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Schistosoma mansoni serine/threonine protein kinase 0.0444 0.1662 0.284
Plasmodium falciparum serine/threonine protein kinase, putative 0.032 0.1087 0.9029
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Schistosoma mansoni tyrosine kinase 0.0193 0.0497 0.0849
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0091 0.0028 0.0022
Echinococcus multilocularis casein kinase I alpha 0.0239 0.0711 0.085
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0186 0.0466 0.1953
Schistosoma mansoni protein kinase 0.0104 0.0089 0.0152
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0246 0.0745 0.1273
Brugia malayi Pre-SET motif family protein 0.0251 0.0769 0.0834
Echinococcus multilocularis mitogen activated protein kinase 11 0.035 0.1226 0.1475
Brugia malayi Protein kinase domain containing protein 0.2075 0.9212 1
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Echinococcus granulosus Immunoglobulin 0.0184 0.0456 0.0447
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0088 0.0013 0.0004
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0479 0.1823 0.1978
Brugia malayi Protein kinase domain containing protein 0.0179 0.0434 0.047
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Brugia malayi Stress-activated protein kinase jnk-1 0.0582 0.2299 0.2494
Loa Loa (eye worm) RasGEF domain-containing protein 0.0092 0.0032 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0179 0.0434 0.1572
Schistosoma mansoni signal transduction protein lnk-related 0.0126 0.019 0.0324
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0126 0.019 0.0218
Loa Loa (eye worm) hypothetical protein 0.0104 0.0089 0.0096
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0111 0.012 0.0481
Loa Loa (eye worm) TK protein kinase 0.0104 0.0089 0.0096
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0891 0.373 0.3724
Echinococcus multilocularis cyclin dependent kinase 1 0.0261 0.0815 0.0976
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0126 0.019 0.0324
Giardia lamblia Kinase, CMGC MAPK 0.0127 0.0195 0.0468
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0123 0.0173 0.0187
Trypanosoma brucei NIMA-related protein kinase 0.0111 0.012 0.035
Onchocerca volvulus 0.107 0.4561 0.8661
Loa Loa (eye worm) RGC/RGC protein kinase 0.0104 0.0089 0.0096
Echinococcus granulosus mitogen activated protein kinase 3 0.0127 0.0195 0.0186
Echinococcus granulosus receptor type guanylyl cyclase 0.0104 0.0089 0.0079
Trichomonas vaginalis CMGC family protein kinase 0.0306 0.102 0.3857
Toxoplasma gondii protein kinase 0.0104 0.0089 0.0238
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0338 0.117 0.4603
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0442 0.1651 0.1791
Schistosoma mansoni serine/threonine protein kinase 0.0582 0.2299 0.3927
Echinococcus multilocularis dual specificity protein kinase clk2 0.0338 0.117 0.1407
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0222 0.0631 0.2428
Trypanosoma cruzi cdc2-related kinase 1 0.0261 0.0815 0.3433
Schistosoma mansoni diacylglycerol kinase theta 0.0092 0.0032 0.0054
Echinococcus granulosus dual specificity 0.0306 0.102 0.1012
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trypanosoma brucei protein kinase, putative 0.0283 0.0915 0.3447
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0306 0.102 0.4308
Schistosoma mansoni protein kinase 0.0177 0.0423 0.0722
Trypanosoma cruzi NIMA-related kinase, putative 0.0111 0.012 0.0481
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0152 0.031 0.0301
Echinococcus multilocularis serine:threonine protein kinase N2 0.064 0.2568 0.3102
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0222 0.0631 0.5138
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0209 0.0571 0.0619
Brugia malayi hypothetical protein 0.0104 0.0089 0.0096
Leishmania major protein kinase, putative 0.0338 0.117 0.4943
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0089 0.0229
Trypanosoma cruzi p21-activated kinase 3, putative 0.012 0.016 0.0652
Onchocerca volvulus 0.0407 0.1489 0.2826
Loa Loa (eye worm) hypothetical protein 0.0104 0.0089 0.0096
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0127 0.0195 0.0801
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0511 0.197 0.2138
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0296 0.0976 0.1171
Echinococcus granulosus Vam6:Vps39 protein 0.0246 0.0745 0.0736
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0222 0.0631 0.0622
Echinococcus granulosus netrin receptor unc 5 0.0104 0.0087 0.0077
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0186 0.0466 0.1268
Echinococcus granulosus SHC transforming protein 3 0.0126 0.019 0.018
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0248 0.0756 0.0747
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0184 0.0456 0.078
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Giardia lamblia Kinase, NEK 0.0104 0.0089 0.000000030784
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Entamoeba histolytica hypothetical protein 0.0105 0.0092 0.0185
Loa Loa (eye worm) hypothetical protein 0.0246 0.0745 0.0808
Schistosoma mansoni tensin 0.0126 0.019 0.0324
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0218 0.0616 0.1053
Brugia malayi Protein kinase domain containing protein 0.0361 0.1277 0.1385
Schistosoma mansoni protein kinase 0.0239 0.0711 0.1215
Schistosoma mansoni septate junction protein 0.0088 0.0013 0.0023
Plasmodium falciparum cGMP-dependent protein kinase 0.0296 0.0976 0.808
Leishmania major protein kinase, putative 0.0092 0.003 0.0099
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0409 0.1498 0.1625
Plasmodium falciparum protein kinase 5 0.0261 0.0815 0.6703
Loa Loa (eye worm) TK/ALK protein kinase 0.0362 0.1283 0.1392
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0196 0.0515 0.2159
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Echinococcus granulosus SH2 motif 0.0126 0.019 0.018
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0248 0.0756 0.0904
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Loa Loa (eye worm) hypothetical protein 0.0222 0.0631 0.0685
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0095 0.0252
Giardia lamblia Kinase, CMGC CLK 0.0338 0.117 0.476
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0631 0.1079
Brugia malayi Immunoglobulin I-set domain containing protein 0.1399 0.6082 0.6602
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0089 0.0229
Schistosoma mansoni hypothetical protein 0.0246 0.0745 0.1273
Trichomonas vaginalis TK family protein kinase 0.0106 0.0095 0.0252
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Trypanosoma brucei Flagellum attachment zone protein 20 0.0104 0.0089 0.0229
Plasmodium vivax calcium-dependent protein kinase, putative 0.0222 0.0631 0.5138
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0104 0.0089 0.0229
Loa Loa (eye worm) guanylate kinase 0.0087 0.0007 0.0007
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0104 0.0089 0.0096
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0272 0.0867 0.1039
Trichomonas vaginalis AGC family protein kinase 0.0354 0.1245 0.4732
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Plasmodium falciparum NIMA related kinase 4 0.0111 0.012 0.0769
Brugia malayi serine/threonine-protein kinase 6 0.032 0.1087 0.1179
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Loa Loa (eye worm) SH2 domain-containing protein 0.0126 0.019 0.0205
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0104 0.0089 0.0152
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0123 0.0173 0.0198
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Echinococcus multilocularis casein kinase I delta 0.0239 0.0711 0.085
Echinococcus granulosus roundabout 2 0.0306 0.1024 0.1015
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0104 0.0089 0.0096
Echinococcus multilocularis myotubularin protein 13 0.0112 0.0123 0.0137
Loa Loa (eye worm) hypothetical protein 0.0087 0.0007 0.0007
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0273 0.0295
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0868 0.3624 0.3934
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0183 0.045 0.1885
Echinococcus granulosus serine/threonine protein kinase 0.0364 0.1292 0.1283
Brugia malayi Bromodomain containing protein 0.0091 0.0025 0.0026
Echinococcus granulosus tyrosine protein kinase Fyn 0.0507 0.1952 0.1944
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0104 0.0089 0.0079
Loa Loa (eye worm) TK protein kinase 0.0633 0.2535 0.2751
Loa Loa (eye worm) hypothetical protein 0.0124 0.0181 0.0196
Schistosoma mansoni protein kinase C mu 0.0479 0.1823 0.3114
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0127 0.0195 0.0801
Echinococcus multilocularis casein kinase i 0.0239 0.0711 0.085
Brugia malayi SH2 domain containing protein 0.0126 0.019 0.0205
Plasmodium falciparum protein kinase, putative 0.0104 0.0089 0.0503
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0337 0.1165 0.1264
Brugia malayi SH2 domain containing protein 0.0126 0.019 0.0205
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Entamoeba histolytica protein kinase, putative 0.0283 0.0915 0.2568
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0338 0.117 0.4439
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0324 0.1107 0.1331
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0092 0.003 0.0099
Brugia malayi Immunoglobulin I-set domain containing protein 0.0123 0.0173 0.0187
Schistosoma mansoni rac gtpase activating protein 0.0092 0.0032 0.0054
Entamoeba histolytica protein kinase, putative 0.0198 0.0523 0.1433
Schistosoma mansoni septate junction protein 0.0088 0.0013 0.0023
Schistosoma mansoni protein kinase 0.0141 0.0259 0.0442
Trypanosoma cruzi polo-like protein kinase, putative 0.0595 0.236 1
Entamoeba histolytica protein kinase, putative 0.0105 0.0092 0.0185
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0196 0.0515 0.0612
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0507 0.1952 0.2355
Brugia malayi Protein kinase domain containing protein 0.0231 0.0673 0.073
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0189 0.048 0.057
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.032 0.1087 0.3065
Trypanosoma cruzi NIMA-related kinase, putative 0.0092 0.003 0.0099
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0102 0.0078 0.0133
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0088 0.0013 0.0014
Toxoplasma gondii AGC kinase 0.0627 0.2507 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0104 0.0089 0.0096
Echinococcus multilocularis Immunoglobulin 0.0184 0.0456 0.0541
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0507 0.1952 0.2355
Echinococcus multilocularis ephrin type A receptor 4 A 0.0246 0.0742 0.0888
Schistosoma mansoni vesicular amine transporter 0.0184 0.0456 0.078
Trichomonas vaginalis STE family protein kinase 0.0189 0.048 0.1753
Entamoeba histolytica protein kinase, putative 0.0092 0.003 0.0005
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0178 0.0429 0.3409
Echinococcus granulosus aurora kinase A 0.032 0.1087 0.1078
Schistosoma mansoni tensin 0.0126 0.019 0.0324
Schistosoma mansoni tyrosine kinase 0.0991 0.4195 0.7167
Echinococcus multilocularis casein kinase ii subunit alpha 0.022 0.0624 0.0745
Schistosoma mansoni serine/threonine protein kinase 0.0716 0.292 0.4988
Echinococcus granulosus defective proboscis extension response 0.0184 0.0456 0.0447
Giardia lamblia Kinase, AGC PKA 0.0248 0.0756 0.2936
Entamoeba histolytica protein kinase, putative 0.0183 0.045 0.1222
Brugia malayi Peripheral plasma membrane protein CASK 0.0087 0.0007 0.0007
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0222 0.0631 0.0754
Schistosoma mansoni serine/threonine protein kinase 0.0354 0.1245 0.2127
Loa Loa (eye worm) TK/DDR protein kinase 0.0104 0.0089 0.0096
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0541 0.2112 0.2548
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Entamoeba histolytica protein kinase domain containing protein 0.0306 0.102 0.2872
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0126 0.019 0.0218
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Echinococcus granulosus microtubule associated protein 2 0.0833 0.3464 0.3457
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0517 0.2 0.2413
Schistosoma mansoni ephrin receptor 0.0246 0.0742 0.1268
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0092 0.0032 0.0034
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0354 0.1245 0.1237
Entamoeba histolytica cysteine surface protein, putative 0.0104 0.0089 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0515 0.0879
Loa Loa (eye worm) AGC/NDR protein kinase 0.0354 0.1245 0.1351
Echinococcus granulosus rho-associated protein kinase 1 0.0716 0.292 0.2913
Echinococcus granulosus casein kinase I alpha 0.0239 0.0711 0.0702
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Entamoeba histolytica PH domain containing protein kinase, putative 0.0268 0.0847 0.237
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1399 0.6082 0.6602
Entamoeba histolytica cell division protein kinase 2, putative 0.0261 0.0815 0.2277
Schistosoma mansoni nephrin 0.0123 0.0173 0.0296
Entamoeba histolytica serine/threonine protein kinase, putative 0.0111 0.012 0.0266
Echinococcus multilocularis casein kinase I alpha 0.0239 0.0711 0.085
Brugia malayi Protein kinase domain containing protein 0.0231 0.0673 0.073
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0196 0.0515 0.414
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0092 0.0032 0.0034
Plasmodium vivax tyrosine kinase-like protein, putative 0.0104 0.0089 0.0503
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0313 0.1054 0.1801
Echinococcus granulosus integrin linked protein kinase 0.0104 0.0089 0.0079
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0305 0.1017 0.3843
Onchocerca volvulus 0.0104 0.0089 0.0167
Echinococcus granulosus protein tyrosine kinase 0.122 0.5253 0.5248
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0517 0.2 0.1992
Schistosoma mansoni kinase 0.0636 0.2548 0.4353
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0104 0.0089 0.0096
Brugia malayi Protein kinase domain containing protein 0.0424 0.157 0.1703
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trypanosoma brucei casein kinase I, isoform 2 0.0239 0.0711 0.2652
Schistosoma mansoni protein kinase 0.0956 0.4029 0.6884
Entamoeba histolytica protein kinase domain containing protein 0.0111 0.0121 0.027
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0102 0.0078 0.0068
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Echinococcus granulosus roundabout 2 0.0123 0.0173 0.0164
Schistosoma mansoni protein kinase 0.0189 0.048 0.082
Echinococcus granulosus casein kinase I delta 0.0239 0.0711 0.0702
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0507 0.1952 0.2355
Plasmodium falciparum tyrosine kinase-like protein 0.0104 0.0089 0.0503
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Loa Loa (eye worm) hypothetical protein 0.0092 0.0032 0.0034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0123 0.0173 0.0187
Trichomonas vaginalis AGC family protein kinase 0.0646 0.2598 1
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Plasmodium vivax glycogen synthase kinase 3, putative 0.0283 0.0915 0.7563
Entamoeba histolytica protein kinase, putative 0.0306 0.102 0.2872
Echinococcus granulosus lachesin 0.0088 0.0013 0.0004
Onchocerca volvulus 0.0427 0.158 0.3
Giardia lamblia Kinase, CAMK CAMKL 0.0196 0.0515 0.1875
Trichomonas vaginalis CAMK family protein kinase 0.0278 0.0892 0.3356
Trichomonas vaginalis CMGC family protein kinase 0.022 0.0624 0.2313
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0126 0.019 0.018
Brugia malayi bone morphogenetic protein type 1 receptor 0.0104 0.0089 0.0096
Echinococcus granulosus protein kinase c eta type 0.0092 0.0032 0.0022
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0595 0.236 1
Leishmania major protein kinase, putative 0.032 0.1087 0.459
Brugia malayi Protein kinase domain containing protein 0.1233 0.5314 0.5768
Echinococcus granulosus retinal guanylyl cyclase 2 0.0104 0.0089 0.0079
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0222 0.0631 0.0754
Loa Loa (eye worm) hypothetical protein 0.0104 0.0089 0.0096
Echinococcus granulosus casein kinase i 0.0239 0.0711 0.0702
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0104 0.0089 0.0229
Leishmania major casein kinase II, putative 0.022 0.0624 0.2623
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0478 0.1816 0.1971
Brugia malayi SH2 domain containing protein 0.0126 0.019 0.0205
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0196 0.0515 0.2159
Plasmodium falciparum tyrosine kinase-like protein 0.0104 0.0089 0.0503
Brugia malayi Protein kinase domain containing protein 0.0776 0.32 0.3472
Echinococcus multilocularis tyrosine kinase 0.0231 0.0673 0.0805
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Entamoeba histolytica protein kinase domain containing protein 0.032 0.1087 0.3065
Brugia malayi Protein kinase domain containing protein 0.0231 0.0673 0.073
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0126 0.019 0.0205
Plasmodium falciparum NIMA related kinase 1 0.0299 0.0992 0.8215
Loa Loa (eye worm) hypothetical protein 0.0218 0.0616 0.0668
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0104 0.0089 0.0079
Schistosoma mansoni tyrosine kinase 0.0891 0.373 0.6372
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Echinococcus multilocularis SH2 domain containing protein 7 0.0126 0.019 0.0218
Schistosoma mansoni unc-13 (munc13) 0.0095 0.0045 0.0076
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0489 0.187 0.1862
Entamoeba histolytica hypothetical protein 0.0104 0.0089 0.0176
Brugia malayi Protein kinase domain containing protein 0.1322 0.5724 0.6213
Schistosoma mansoni tyrosine kinase 0.0701 0.2852 0.4872
Loa Loa (eye worm) hypothetical protein 0.066 0.2661 0.2888
Entamoeba histolytica protein kinase, putative 0.0161 0.035 0.0932
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0489 0.187 0.2029
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0246 0.0745 0.0892
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Brugia malayi Immunoglobulin I-set domain containing protein 0.0111 0.0119 0.0128
Echinococcus multilocularis tyrosine protein kinase HCK 0.0298 0.0986 0.1184
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0183 0.045 0.1637
Entamoeba histolytica hypothetical protein 0.0092 0.0032 0.001
Schistosoma mansoni serine/threonine protein kinase 0.012 0.016 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.0868 0.3624 0.6192
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0261 0.0815 0.0884
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.035 0.1226 0.5181
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.022 0.0624 0.5074
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0475 0.1806 0.1798
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Plasmodium vivax tyrosine kinase-like protein, putative 0.0178 0.0429 0.3409
Loa Loa (eye worm) TK/FAK protein kinase 0.1233 0.5314 0.5768
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trichomonas vaginalis CAMK family protein kinase 0.0595 0.236 0.9073
Entamoeba histolytica protein kinase, putative 0.0224 0.0644 0.1783
Schistosoma mansoni nephrin 0.0266 0.0837 0.1431
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0092 0.003 0.0099
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0104 0.0089 0.0238
Loa Loa (eye worm) hypothetical protein 0.0227 0.0656 0.0712
Schistosoma mansoni tyrosine kinase 0.0786 0.3246 0.5545
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Loa Loa (eye worm) hypothetical protein 0.0124 0.0181 0.0196
Entamoeba histolytica protein kinase, putative 0.0646 0.2598 0.7439
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Onchocerca volvulus Serine\/threonine kinase homolog 0.0361 0.1277 0.2423
Entamoeba histolytica tyrosin kinase, putative 0.0104 0.0089 0.0176
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0446 0.167 0.1812
Echinococcus multilocularis casein kinase I gamma 0.0336 0.1159 0.1393
Schistosoma mansoni serine/threonine protein kinase 0.0269 0.085 0.1452
Echinococcus granulosus protein kinase shaggy 0.0283 0.0915 0.0906
Echinococcus multilocularis epidermal growth factor receptor 0.135 0.5853 0.7085
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Brugia malayi Prion-like- 0.0088 0.0013 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Echinococcus multilocularis signal transduction protein lnk realted 0.0126 0.019 0.0218
Leishmania major protein kinase A catalytic subunit 0.0248 0.0756 0.3183
Plasmodium falciparum calcium-dependent protein kinase 3 0.0222 0.0631 0.5138
Echinococcus multilocularis nervana 2 0.0272 0.0867 0.1039
Plasmodium falciparum calcium-dependent protein kinase 4 0.0222 0.0631 0.5138
Echinococcus granulosus nervana 2 0.0272 0.0867 0.0858
Loa Loa (eye worm) RGC/RGC protein kinase 0.0104 0.0089 0.0096
Echinococcus multilocularis peroxidasin 0.0089 0.0016 0.0008
Entamoeba histolytica receptor protein kinase, putative 0.0104 0.0089 0.0176
Schistosoma mansoni protein kinase 0.0583 0.2305 0.3938
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0104 0.0089 0.0176
Entamoeba histolytica hypothetical protein 0.0837 0.3483 1
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.0978 0.1671
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0808 0.3344 0.363
Brugia malayi Sex muscle abnormal protein 5 0.0209 0.0571 0.0619
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0089 0.0096
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0186 0.0466 0.1953
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0239 0.0711 0.0771
Brugia malayi map kinase activated protein kinase protein 2 0.0868 0.3624 0.3933
Echinococcus multilocularis cyclin dependent kinase 5 0.0261 0.0815 0.0976
Trichomonas vaginalis CMGC family protein kinase 0.0283 0.0915 0.3447
Echinococcus multilocularis nervana 2 0.0272 0.0867 0.1039
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0189 0.048 0.057
Trichomonas vaginalis CMGC family protein kinase 0.0283 0.0915 0.3447
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0956 0.4029 0.4024
Schistosoma mansoni suppressor of cytokine signaling 0.0126 0.019 0.0324
Echinococcus granulosus serine:threonine protein kinase N2 0.064 0.2568 0.2561
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.012 0.016 0.0652
Echinococcus granulosus serine:threonine protein kinase 0.0251 0.0767 0.0758
Brugia malayi SH2 domain containing protein 0.0126 0.019 0.0205
Entamoeba histolytica protein kinase, putative 0.0298 0.0986 0.2773
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0089 0.0229
Brugia malayi Receptor family ligand binding region containing protein 0.0104 0.0089 0.0096
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.0673 0.073
Schistosoma mansoni serine/threonine protein kinase 0.054 0.2103 0.3593
Schistosoma mansoni titin 0.0154 0.032 0.0547
Schistosoma mansoni serine/threonine RGC 0.0104 0.0089 0.0152
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Schistosoma mansoni growth factor receptor-bound protein 0.0209 0.0571 0.0975
Schistosoma mansoni serine/threonine protein kinase 0.0338 0.117 0.1999
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Brugia malayi Protein kinase domain containing protein 0.0231 0.0673 0.073
Schistosoma mansoni roundabout 0.0088 0.0013 0.0023
Brugia malayi Tyrosine-protein kinase PR2 0.0104 0.0089 0.0096
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0111 0.012 0.0769
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0239 0.0711 0.0771
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0177 0.0423 0.1767
Loa Loa (eye worm) hypothetical protein 0.0141 0.0258 0.028
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0776 0.32 0.3472
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0104 0.0089 0.0079
Leishmania major hypothetical protein, conserved 0.0104 0.0089 0.0349
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0089 0.0096
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0222 0.0631 0.2428
Trichomonas vaginalis TKL family protein kinase 0.0106 0.0095 0.0252
Schistosoma mansoni protein kinase 0.0956 0.4029 0.6884
Echinococcus granulosus hypothetical protein 0.0266 0.0836 0.0827
Loa Loa (eye worm) hypothetical protein 0.0146 0.0281 0.0304
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0126 0.019 0.0218
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Loa Loa (eye worm) TK protein kinase 0.0104 0.0089 0.0096
Echinococcus multilocularis tyrosine protein kinase 0.0633 0.2535 0.3062
Trichomonas vaginalis AGC family protein kinase 0.0377 0.1351 0.5142
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0815 0.3055
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Echinococcus multilocularis c src tyrosine kinase 0.0313 0.1054 0.1267
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0776 0.32 0.3473
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0104 0.0089 0.0079
Echinococcus multilocularis tyrosine protein kinase csk 0.0104 0.0089 0.0096
Entamoeba histolytica protein kinase domain containing protein 0.0446 0.167 0.4752
Plasmodium vivax serine/threonine kinase-1, putative 0.0338 0.117 0.974
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0184 0.0456 0.078
Loa Loa (eye worm) TK/FER protein kinase 0.0104 0.0089 0.0096
Schistosoma mansoni titin 0.0088 0.0013 0.0023
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Onchocerca volvulus 0.0104 0.0089 0.0167
Schistosoma mansoni serine/threonine protein kinase 0.032 0.1087 0.1857
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0269 0.085 0.3582
Entamoeba histolytica PH domain containing protein kinase, putative 0.0268 0.0847 0.237
Echinococcus granulosus dual specificity 0.0306 0.102 0.1012
Brugia malayi hypothetical protein 0.0124 0.0181 0.0195
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Loa Loa (eye worm) hypothetical protein 0.0126 0.019 0.0205
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0104 0.0089 0.0079
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Entamoeba histolytica protein kinase, putative 0.0183 0.045 0.1222
Echinococcus granulosus calcium activated potassium channel 0.0297 0.0978 0.097
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Schistosoma mansoni cell adhesion molecule 0.0123 0.0173 0.0296
Echinococcus granulosus tyrosine protein kinase Src42A 0.0507 0.1952 0.1944
Brugia malayi Immunoglobulin I-set domain containing protein 0.0589 0.2333 0.2532
Schistosoma mansoni neuroglian 0.0123 0.0173 0.0296
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0184 0.0456 0.0541
Onchocerca volvulus 0.0306 0.1021 0.1938
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0123 0.0173 0.0198
Loa Loa (eye worm) hypothetical protein 0.0209 0.0571 0.0619
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0218 0.0616 0.0735
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0104 0.0089 0.0176
Echinococcus granulosus fibroblast growth factor receptor 4 0.0541 0.2112 0.2104
Entamoeba histolytica protein kinase domain containing protein 0.022 0.0624 0.1725
Loa Loa (eye worm) TK protein kinase 0.0104 0.0089 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Schistosoma mansoni serine/threonine protein kinase 0.0409 0.1498 0.2559
Giardia lamblia Kinase, CMGC CDK 0.0261 0.0815 0.3196
Loa Loa (eye worm) hypothetical protein 0.0407 0.1489 0.1616
Brugia malayi Tensin 0.0126 0.019 0.0205
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0222 0.0631 0.0684
Trypanosoma cruzi polo-like protein kinase, putative 0.0595 0.236 1
Loa Loa (eye worm) hypothetical protein 0.0117 0.0146 0.0158
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Brugia malayi integrin-linked kinase 0.0104 0.0089 0.0096
Echinococcus multilocularis calcium activated potassium channel 0.0297 0.0978 0.1174
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Toxoplasma gondii NEK kinase 0.0111 0.012 0.0363
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0248 0.0756 0.293
Trichomonas vaginalis AGC family protein kinase 0.0248 0.0756 0.2826
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Echinococcus granulosus serine:threonine protein kinase 0.0251 0.0767 0.0758
Trichomonas vaginalis STE family protein kinase 0.0104 0.0089 0.0229
Leishmania major serine/threonine-protein kinase, putative 0.0111 0.012 0.0481
Trypanosoma brucei aurora B kinase 0.032 0.1087 0.4115
Entamoeba histolytica protein kinase, putative 0.0269 0.085 0.2378
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0104 0.0089 0.0096
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0104 0.0089 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0595 0.236 0.9073
Onchocerca volvulus 0.0231 0.0673 0.1277
Schistosoma mansoni protein kinase 0.032 0.1087 0.1857
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0808 0.3344 0.3338
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0815 0.3055
Trichomonas vaginalis CK1 family protein kinase 0.0239 0.0711 0.2652
Schistosoma mansoni suppressor of cytokine signaling 0.0126 0.019 0.0324
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0104 0.0089 0.0096
Echinococcus granulosus dual specificity protein kinase clk2 0.0338 0.117 0.1161
Giardia lamblia Kinase, AGC AKT 0.0257 0.0797 0.3118
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Trypanosoma brucei cdc2-related kinase 1 0.0261 0.0815 0.3055
Loa Loa (eye worm) hypothetical protein 0.0104 0.0089 0.0096
Loa Loa (eye worm) hypothetical protein 0.0089 0.0016 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0756 0.1291
Entamoeba histolytica serine/threonine protein kinase, putative 0.0196 0.0515 0.1408
Loa Loa (eye worm) hypothetical protein 0.0224 0.0643 0.0697
Echinococcus multilocularis tyrosine protein kinase Srms 0.0425 0.1571 0.1893
Onchocerca volvulus 0.0126 0.019 0.0358
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0089 0.0229
Brugia malayi Protein kinase domain containing protein 0.1322 0.5724 0.6213
Brugia malayi Protein kinase domain containing protein 0.0183 0.045 0.0488
Brugia malayi Tyrosine-protein kinase abl-1 0.0488 0.1864 0.2022
Echinococcus granulosus hemicentin 1 0.0088 0.0013 0.0004
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Echinococcus multilocularis serine:threonine protein kinase 38 0.0354 0.1245 0.1498
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1089 0.4646 0.4641
Echinococcus granulosus activin receptor type 0.0177 0.0423 0.0413
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0354 0.1245 0.1237
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Giardia lamblia Kinase, NEK 0.0299 0.0992 0.3974
Schistosoma mansoni serine/threonine protein kinase 0.0475 0.1806 0.3086
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Entamoeba histolytica serine/threonine kinase, putative 0.0104 0.0089 0.0176
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.0673 0.073
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0354 0.1245 0.1498
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.054 0.2103 0.2538
Loa Loa (eye worm) hypothetical protein 0.0123 0.0173 0.0187
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0126 0.019 0.0358
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.012 0.035
Schistosoma mansoni serine/threonine protein kinase 0.0517 0.2 0.3417
Trichomonas vaginalis STE family protein kinase 0.0189 0.048 0.1753
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0269 0.085 0.3582
Loa Loa (eye worm) hypothetical protein 0.0104 0.0089 0.0096
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0222 0.0631 0.2428
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0088 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0087 0.001 0.001
Schistosoma mansoni protein kinase 0.0104 0.0089 0.0152
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0222 0.0631 0.5138
Echinococcus granulosus casein kinase I alpha 0.0239 0.0711 0.0702
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0104 0.0089 0.0096
Echinococcus multilocularis roundabout 2 0.0123 0.0173 0.0198
Trichomonas vaginalis CMGC family protein kinase 0.0444 0.1662 0.6357
Echinococcus multilocularis SH2 motif 0.0126 0.019 0.0218
Onchocerca volvulus 0.0231 0.0673 0.1277
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0507 0.1952 0.2355
Trichomonas vaginalis CMGC family protein kinase 0.022 0.0624 0.2313
Schistosoma mansoni hypothetical protein 0.0092 0.0032 0.0054
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0318 0.1079 0.107
Echinococcus granulosus N chimaerin 0.0218 0.0616 0.0607
Echinococcus granulosus suppressor of cytokine signaling 6 0.0126 0.019 0.018
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0815 0.1392
Brugia malayi hypothetical protein 0.0231 0.0673 0.073
Brugia malayi hypothetical protein 0.0246 0.0745 0.0808
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0196 0.0515 0.0558
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0325 0.0556
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0104 0.0089 0.0167
Brugia malayi Hr1 repeat family protein 0.064 0.2568 0.2787
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.0146 0.0453
Schistosoma mansoni serine/threonine protein kinase 0.0296 0.0976 0.1667
Trypanosoma cruzi Protein kinase B 0.0364 0.1292 0.5461
Trichomonas vaginalis AGC family protein kinase 0.032 0.1087 0.4115
Onchocerca volvulus 0.0141 0.0258 0.0489
Echinococcus multilocularis integrin linked protein kinase 0.0104 0.0089 0.0096
Entamoeba histolytica casein kinase, putative 0.022 0.0624 0.1725
Loa Loa (eye worm) TK/FER protein kinase 0.0899 0.3769 0.409
Brugia malayi Protein kinase domain containing protein 0.0421 0.1554 0.1686
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0195 0.0643
Loa Loa (eye worm) hypothetical protein 0.0088 0.0013 0.0014
Echinococcus multilocularis serine threonine protein kinase 0.0444 0.1663 0.2004
Echinococcus granulosus c src tyrosine kinase 0.0313 0.1054 0.1046
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0338 0.117 0.4439
Loa Loa (eye worm) hypothetical protein 0.0184 0.0456 0.0495
Echinococcus granulosus cyclin dependent kinase 5 0.0261 0.0815 0.0806
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0345 0.1201 0.1192
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0104 0.0089 0.0229
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.035 0.1226 0.133
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0126 0.019 0.0358
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0248 0.0756 0.0904
Echinococcus multilocularis tensin 0.0126 0.019 0.0218
Schistosoma mansoni serine/threonine protein kinase 0.0306 0.102 0.1743
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0616 0.0668
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0111 0.012 0.0481
Loa Loa (eye worm) TK/INSR protein kinase 0.0991 0.4195 0.4553
Toxoplasma gondii AGC kinase 0.0248 0.0756 0.293
Schistosoma mansoni protein kinase 0.0104 0.0089 0.0152
Loa Loa (eye worm) hypothetical protein 0.0251 0.0767 0.0832
Entamoeba histolytica hypothetical protein 0.0104 0.0089 0.0176
Echinococcus granulosus SH2 domain containing adapter protein F 0.0126 0.019 0.018
Loa Loa (eye worm) hypothetical protein 0.0225 0.0645 0.0699
Entamoeba histolytica tyrosin kinase, putative 0.0104 0.0089 0.0176
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0257 0.0797 0.0864
Loa Loa (eye worm) hypothetical protein 0.0427 0.158 0.1715
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.035 0.1226 0.5181
Echinococcus granulosus tyrosine protein kinase csk 0.0104 0.0089 0.0079
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.0673 0.073
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0126 0.019 0.0324
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0261 0.0815 0.3433
Loa Loa (eye worm) hypothetical protein 0.0126 0.019 0.0205
Echinococcus granulosus neuroglian 0.0232 0.0678 0.0669
Brugia malayi Cam kinase protein 1 0.0222 0.0631 0.0684
Schistosoma mansoni tensin-related 0.0126 0.019 0.0324
Onchocerca volvulus 0.0239 0.0711 0.1349
Schistosoma mansoni serine/threonine protein kinase 0.0354 0.1245 0.2127
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0248 0.0756 0.2826
Toxoplasma gondii NEK kinase 0.0111 0.012 0.0363
Trypanosoma cruzi casein kinase, putative 0.0239 0.0711 0.2993
Onchocerca volvulus 0.0126 0.019 0.0358
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0218 0.0616 0.0668
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Schistosoma mansoni tyrosine kinase 0.0507 0.1952 0.3335
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0095 0.0252
Brugia malayi Guanylyl cyclase protein 23 0.0104 0.0089 0.0096
Echinococcus multilocularis serine:threonine protein kinase 3 0.0565 0.2223 0.2683
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Entamoeba histolytica diacylglycerol kinase, putative 0.0092 0.0032 0.001
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0176 0.0422 0.0413
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0127 0.0195 0.0801
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Loa Loa (eye worm) hypothetical protein 0.0088 0.0013 0.0014
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Giardia lamblia Kinase, NEK 0.0299 0.0992 0.3974
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0126 0.019 0.018
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0102 0.0078 0.0082
Brugia malayi diacylglycerol kinase 0.0092 0.0032 0.0034
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0246 0.0745 0.3138
Brugia malayi C-terminal src kinase protein 1 0.0104 0.0089 0.0096
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0361 0.1277 0.1536
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Echinococcus multilocularis tensin 0.0126 0.019 0.0218
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0283 0.0915 0.3574
Entamoeba histolytica diacylglycerol kinase, putative 0.0092 0.0032 0.001
Brugia malayi Pleckstrin Homology Domain 0.0112 0.0123 0.0133
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0095 0.0044 0.0055
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0251 0.0767 0.0832
Schistosoma mansoni protein kinase 0.0337 0.1165 0.199
Entamoeba histolytica hypothetical protein 0.0104 0.0089 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.079 0.135
Schistosoma mansoni cell adhesion molecule 0.0259 0.0803 0.1371
Trichomonas vaginalis AGC family protein kinase 0.032 0.1087 0.4115
Loa Loa (eye worm) hypothetical protein 0.0092 0.0032 0.0034
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0167 0.0377 0.1575
Loa Loa (eye worm) hypothetical protein 0.0398 0.1448 0.1571
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0338 0.117 0.4943
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.012 0.016 0.0173
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0446 0.167 0.2013
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0104 0.0089 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Echinococcus granulosus tyrosine protein kinase pr2 0.0104 0.0089 0.0079
Trichomonas vaginalis CMGC family protein kinase 0.022 0.0624 0.2313
Echinococcus multilocularis lachesin 0.0088 0.0013 0.0004
Echinococcus multilocularis myosin iiia 0.0186 0.0466 0.0554
Echinococcus multilocularis roundabout 2 0.0306 0.1024 0.123
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0104 0.0089 0.0096
Schistosoma mansoni serine/threonine-protein kinase 0.0364 0.1292 0.2207
Schistosoma mansoni tyrosine kinase 0.0104 0.0089 0.0152
Schistosoma mansoni atypical protein kinase C 0.0642 0.258 0.4407
Brugia malayi Immunoglobulin I-set domain containing protein 0.0088 0.0013 0.0013
Brugia malayi Protein kinase domain containing protein 0.0231 0.0673 0.073
Entamoeba histolytica hypothetical protein 0.0102 0.0078 0.0143
Plasmodium falciparum calcium-dependent protein kinase 2 0.0222 0.0631 0.5138
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0338 0.117 0.4943
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0104 0.0089 0.0152
Giardia lamblia Kinase, CMGC GSK 0.0283 0.0915 0.3639
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Loa Loa (eye worm) hypothetical protein 0.0092 0.0032 0.0034
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0425 0.1571 0.1893
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Onchocerca volvulus 0.0104 0.0089 0.0167
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Echinococcus multilocularis transfer RNA-Thr 0.0104 0.0089 0.0096
Loa Loa (eye worm) hypothetical protein 0.0126 0.019 0.0205
Trichomonas vaginalis CMGC family protein kinase 0.0306 0.102 0.3857
Echinococcus granulosus NCK adaptor protein 0.0209 0.0571 0.0562
Onchocerca volvulus 0.0246 0.0745 0.1414
Echinococcus multilocularis natriuretic peptide receptor 1 0.0104 0.0089 0.0096
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0149 0.0294 0.0318
Echinococcus granulosus SH2 motif 0.0126 0.019 0.018
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0123 0.0173 0.0296
Loa Loa (eye worm) hypothetical protein 0.0126 0.019 0.0205
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0815 0.3055
Brugia malayi SH2 domain containing protein 0.0899 0.3769 0.409
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0688 0.2789 0.337
Schistosoma mansoni serine/threonine protein kinase 0.105 0.4469 0.7634
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.0176
Entamoeba histolytica hypothetical protein 0.0092 0.003 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.012 0.016 0.0274
Trichomonas vaginalis CMGC family protein kinase 0.022 0.0624 0.2313
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0338 0.117 0.4943
Echinococcus granulosus unc 13 munc13 0.0095 0.0045 0.0035
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0104 0.0089 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0756 0.1291
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0104 0.0089 0.0176
Echinococcus multilocularis 0.0266 0.0836 0.1002
Entamoeba histolytica hypothetical protein 0.0104 0.0089 0.0176
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0409 0.1498 0.1626
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0044 0.0055
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Brugia malayi Immunoglobulin I-set domain containing protein 0.0088 0.0013 0.0013
Echinococcus multilocularis tyrosine protein kinase Blk 0.0425 0.1571 0.1893
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0126 0.019 0.0218
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Trypanosoma brucei Casein kinase II 0.022 0.0624 0.2313
Schistosoma mansoni shc transforming protein 0.0126 0.019 0.0324
Loa Loa (eye worm) hypothetical protein 0.0126 0.019 0.0205
Entamoeba histolytica cell division protein kinase 2, putative 0.0261 0.0815 0.2277
Plasmodium falciparum protein kinase, putative 0.0177 0.0423 0.3354
Giardia lamblia Kinase, AGC PKA 0.0345 0.1201 0.4895
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0095 0.0045 0.0035
Loa Loa (eye worm) CDC7 protein kinase 0.0444 0.1662 0.1804
Loa Loa (eye worm) hypothetical protein 0.0112 0.0123 0.0133
Entamoeba histolytica protein kinase, putative 0.0092 0.003 0.0005
Brugia malayi SH2 domain containing protein 0.0231 0.0673 0.073
Trichomonas vaginalis CK1 family protein kinase 0.0239 0.0711 0.2652
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Brugia malayi Variant SH3 domain containing protein 0.0087 0.0007 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0104 0.0089 0.0096
Toxoplasma gondii NEK kinase 0.0111 0.012 0.0363
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0283 0.0915 0.3861
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Echinococcus granulosus serine:threonine kinase SAD 1 0.0196 0.0515 0.0505
Onchocerca volvulus 0.0644 0.2586 0.491
Brugia malayi Guanylate kinase family protein 0.0087 0.0007 0.0007
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0177 0.0423 0.1529
Schistosoma mansoni cell adhesion molecule 0.0123 0.0173 0.0296
Trichomonas vaginalis CMGC family protein kinase 0.0306 0.102 0.3857
Schistosoma mansoni serine/threonine protein kinase 0.0489 0.187 0.3194
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0135 0.041
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.032 0.0547
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0409 0.1498 0.149
Loa Loa (eye worm) AGC/AKT protein kinase 0.0646 0.2598 0.282
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0111 0.012 0.0481
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0222 0.0631 0.0685
Loa Loa (eye worm) hypothetical protein 0.0528 0.2051 0.2226
Trichomonas vaginalis AGC family protein kinase 0.0397 0.1442 0.5497
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0183 0.045 0.0488
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0104 0.0089 0.0096
Echinococcus multilocularis protein tyrosine kinase 0.122 0.5253 0.6357
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0515 0.0879
Brugia malayi P38 map kinase family protein 2 0.035 0.1226 0.133
Echinococcus granulosus tyrosine protein kinase csk 0.0104 0.0089 0.0079
Leishmania major protein kinase, putative 0.0222 0.0631 0.2654
Brugia malayi probable protein kinase 0.0583 0.2305 0.2501
Schistosoma mansoni rap gtpase-activating protein 0.0246 0.0745 0.1273
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0248 0.0756 0.3183
Echinococcus multilocularis serine:threonine protein kinase N2 0.0354 0.1245 0.1498
Echinococcus granulosus serine:threonine protein kinase 12 B 0.032 0.1087 0.1078
Brugia malayi Furin-like cysteine rich region family protein 0.135 0.5853 0.6353
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0127 0.0195 0.0211
Echinococcus multilocularis PAK box P21 Rho binding 0.0141 0.0259 0.0302
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0248 0.0756 0.0819
Entamoeba histolytica receptor protein kinase, putative 0.0104 0.0089 0.0176
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Echinococcus multilocularis NCK adaptor protein 0.0213 0.0591 0.0705
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0449 0.1685 0.1828
Schistosoma mansoni serine/threonine protein kinase 0.0336 0.1159 0.198
Onchocerca volvulus 0.0444 0.1662 0.3156
Schistosoma mansoni tyrosine kinase 0.0891 0.373 0.6372
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0299 0.0992 0.3882
Echinococcus granulosus tyrosine protein kinase Src42A 0.0324 0.1107 0.1099
Loa Loa (eye worm) hypothetical protein 0.0104 0.0089 0.0096
Echinococcus multilocularis casein kinase I delta 0.0239 0.0711 0.085
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0176 0.0422 0.05
Schistosoma mansoni protein kinase 0.0189 0.048 0.082
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0111 0.0119 0.0128
Brugia malayi Protein kinase domain containing protein 0.0444 0.1662 0.1804
Loa Loa (eye worm) hypothetical protein 0.0231 0.0673 0.073
Giardia lamblia Aurora kinase 0.032 0.1087 0.4394
Entamoeba histolytica PH domain containing protein kinase, putative 0.0092 0.003 0.0005
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0361 0.1277 0.1268
Echinococcus granulosus mitogen activated protein kinase 14 0.035 0.1226 0.1217
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0111 0.012 0.0481
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.045 0.0769
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.0631 0.2342
Entamoeba histolytica hypothetical protein 0.0269 0.085 0.2378
Trichomonas vaginalis CAMK family protein kinase 0.0253 0.0777 0.2908
Mycobacterium ulcerans hypothetical protein 0.0224 0.0642 0.5
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0183 0.045 0.1885
Echinococcus granulosus mitogen activated protein kinase 11 0.035 0.1226 0.1217
Loa Loa (eye worm) hypothetical protein 0.0511 0.1971 0.2139
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.054 0.2103 0.2096
Loa Loa (eye worm) TK/FER protein kinase 0.0231 0.0673 0.073
Schistosoma mansoni protein kinase 0.0519 0.2009 0.3432
Giardia lamblia Kinase, NEK 0.0111 0.012 0.0137
Toxoplasma gondii diacylglycerol kinase, putative 0.0092 0.0032 0.0007
Toxoplasma gondii AGC kinase 0.0248 0.0756 0.293
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0109 0.0109 0.0121
Trypanosoma cruzi aurora B kinase, putative 0.032 0.1087 0.459
Schistosoma mansoni tyrosine kinase 0.0823 0.3415 0.5835
Trichomonas vaginalis CAMK family protein kinase 0.0595 0.236 0.9073
Brugia malayi Temporarily assigned gene name protein 59 0.0246 0.0745 0.0808
Brugia malayi Protein kinase domain containing protein 0.0633 0.2535 0.2751
Schistosoma mansoni serine/threonine-protein kinase 0.0364 0.1292 0.2207
Loa Loa (eye worm) hypothetical protein 0.0197 0.0516 0.056
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0248 0.0756 0.3183
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0475 0.1806 0.2178
Schistosoma mansoni tyrosine kinase 0.135 0.5853 1
Loa Loa (eye worm) hypothetical protein 0.0218 0.0616 0.0668
Echinococcus granulosus peroxidasin 0.0089 0.0016 0.0007
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0595 0.236 0.2353
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0088 0.0013 0.0023
Brugia malayi Fes/CIP4 homology domain containing protein 0.025 0.0761 0.0825
Entamoeba histolytica PH domain containing protein kinase, putative 0.0092 0.003 0.0005
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0183 0.045 0.1697
Loa Loa (eye worm) hypothetical protein 0.0279 0.0898 0.0974
Loa Loa (eye worm) hypothetical protein 0.0306 0.1021 0.1108
Loa Loa (eye worm) STAT protein 0.0126 0.019 0.0205
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0127 0.0195 0.0801
Entamoeba histolytica protein kinase, putative 0.0141 0.0259 0.0668
Plasmodium falciparum casein kinase 1 0.0239 0.0711 0.5819
Brugia malayi Protein kinase domain containing protein 0.0336 0.1159 0.1257
Loa Loa (eye worm) SH2 domain-containing protein 0.0126 0.019 0.0205
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0104 0.0089 0.0152
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0261 0.0815 0.0884
Entamoeba histolytica serine/threonine kinase, putative 0.0104 0.0089 0.0176
Echinococcus granulosus tyrosine protein kinase Blk 0.0425 0.1571 0.1562
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Entamoeba histolytica tyrosine kinase, putative 0.0104 0.0089 0.0176
Brugia malayi casein kinase I 0.0239 0.0711 0.0771
Brugia malayi Protein kinase domain containing protein 0.0478 0.1816 0.1971
Echinococcus multilocularis protein KINase family member (kin 25) 0.0104 0.0089 0.0096
Echinococcus granulosus roundabout 2 0.0123 0.0173 0.0164
Loa Loa (eye worm) hypothetical protein 0.0184 0.0456 0.0495
Schistosoma mansoni protein kinase 0.0104 0.0089 0.0152
Loa Loa (eye worm) hypothetical protein 0.0101 0.0073 0.0078
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0248 0.0756 0.0747
Onchocerca volvulus 0.0095 0.0045 0.0083
Schistosoma mansoni hypothetical protein 0.0225 0.0645 0.1101
Trichomonas vaginalis AGC family protein kinase 0.0646 0.2598 1
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0092 0.003 0.0099
Schistosoma mansoni growth factor receptor-bound protein 0.0213 0.0591 0.101
Brugia malayi RhoGAP domain containing protein 0.0092 0.0032 0.0034
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0104 0.0089 0.0176
Schistosoma mansoni protein kinase 0.0956 0.4029 0.6884
Brugia malayi SRC-1 0.0507 0.1952 0.2118
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0283 0.0915 0.1098
Brugia malayi Raf kinase 0.0104 0.0089 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Echinococcus granulosus expressed conserved protein 0.0126 0.019 0.018
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0154 0.032 0.0347
Echinococcus multilocularis tyrosine protein kinase Abl 0.0488 0.1864 0.2248
Trypanosoma cruzi cdc2-related kinase 1 0.0261 0.0815 0.3433
Brugia malayi p70 ribosomal S6 kinase beta 0.0627 0.2507 0.272
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0209 0.0571 0.0619
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0296 0.0976 0.3818
Entamoeba histolytica serine/threonine kinase, putative 0.0104 0.0089 0.0176
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.012 0.016 0.0506
Echinococcus granulosus geminin 0.0205 0.0553 0.0543
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.0176
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0345 0.1201 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.019 0.0205
Onchocerca volvulus 0.0286 0.093 0.1764
Brugia malayi putative serine/threonine kinase SADA gamma 0.0196 0.0515 0.0558
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0179 0.0434 0.047
Echinococcus granulosus Rac GTPase activating protein 1 0.0092 0.0032 0.0022
Trypanosoma brucei polo-like protein kinase 0.0595 0.236 0.9073
Trypanosoma cruzi casein kinase, putative 0.0239 0.0711 0.2993
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0104 0.0089 0.0176
Echinococcus multilocularis geminin 0.0205 0.0553 0.0658
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0273 0.0295
Trichomonas vaginalis TKL family protein kinase 0.0104 0.0089 0.0229
Giardia lamblia Kinase, CK1 Casein kinase 0.0239 0.0711 0.274
Schistosoma mansoni tyrosine kinase 0.122 0.5253 0.8974
Echinococcus multilocularis cyclin dependent kinase 1 0.0261 0.0815 0.0976
Entamoeba histolytica serine/threonine kinase, putative 0.0104 0.0089 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.0515 0.1887
Loa Loa (eye worm) hypothetical protein 0.0126 0.019 0.0205
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0345 0.1201 0.5073
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0104 0.0089 0.0167
Loa Loa (eye worm) TK protein kinase 0.0589 0.2333 0.2532
Trichomonas vaginalis STE family protein kinase 0.0189 0.048 0.1753
Loa Loa (eye worm) RGC/RGC protein kinase 0.0104 0.0089 0.0096
Echinococcus multilocularis tyrosine protein kinase pr2 0.0104 0.0089 0.0096
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0123 0.0173 0.0198
Echinococcus multilocularis netrin receptor unc 5 0.0104 0.0087 0.0094
Brugia malayi Temporarily assigned gene name protein 59 0.0284 0.0921 0.0999
Trypanosoma cruzi casein kinase, putative 0.0239 0.0711 0.2993
Entamoeba histolytica protein kinase, putative 0.0093 0.0034 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0239 0.0711 0.1215
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0306 0.102 0.1107
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0096
Entamoeba histolytica hypothetical protein 0.0092 0.003 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0537 0.2089 0.3569
Trypanosoma cruzi cdc2-related kinase 3 0.0261 0.0815 0.3433
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0446 0.167 0.1662
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0377 0.1351 0.1465
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2075 0.9212 1
Onchocerca volvulus 0.0283 0.0915 0.1737
Brugia malayi SH2 domain containing protein 0.0126 0.019 0.0205
Loa Loa (eye worm) thyroid receptor interactor 0.025 0.0761 0.0825

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.1 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 1.7783 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) = 3.1623 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.0795 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 7.3078 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 19.9526 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 23.1093 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 44.6684 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.