Detailed information for compound 1726602

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 374.27 | Formula: C18H9F3N2O4
  • H donors: 3 H acceptors: 4 LogP: 2.73 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)c1ccc2c(c1)N/C(=C/1\C(=O)Nc3c1cccc3C(F)(F)F)/C2=O
  • InChi: 1S/C18H9F3N2O4/c19-18(20,21)10-3-1-2-9-12(16(25)23-13(9)10)14-15(24)8-5-4-7(17(26)27)6-11(8)22-14/h1-6,22H,(H,23,25)(H,26,27)/b14-12-
  • InChiKey: TWSHBECDMINHSW-OWBHPGMISA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Sus scrofa Glycogen synthase kinase 3 beta Starlite/ChEMBL References
Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 Starlite/ChEMBL References
Rattus norvegicus Dual specificity tyrosine-phosphorylation-regulated kinase 1A Starlite/ChEMBL References
Homo sapiens cyclin-dependent kinase 5 Starlite/ChEMBL References
Sus scrofa Casein kinase I isoform alpha Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania mexicana protein kinase, putative,dual-specificity protein kinase, putative Get druggable targets OG5_127439 All targets in OG5_127439
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma congolense dual-specificity protein kinase, putative Get druggable targets OG5_127439 All targets in OG5_127439
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Plasmodium yoelii Protein kinase domain, putative Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium knowlesi casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis casein kinase I delta Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma brucei CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans second truncated form of RIM11 Serine/threonine protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus multilocularis glycogen synthase kinase 3 beta Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma congolense casein kinase I, isoform 2 Get druggable targets OG5_126780 All targets in OG5_126780
Toxoplasma gondii casein kinase I Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma congolense cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum Casein kinase I isoform delta, putative Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania major cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi casein kinase, delta isoform, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania mexicana protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Giardia lamblia Kinase, CMGC GSK Get druggable targets OG5_126888 All targets in OG5_126888
Brugia malayi cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus granulosus cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium yoelii casein kinase i Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma japonicum ko:K08822 glycogen synthase kinase 3 alpha, putative Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium falciparum casein kinase 1 Get druggable targets OG5_126780 All targets in OG5_126780
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis CK1 family protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania major casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium knowlesi Cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi casein kinase I Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma brucei gambiense protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Brugia malayi intracellular kinase Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CK1 family protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Onchocerca volvulus Get druggable targets OG5_126888 All targets in OG5_126888
Cryptosporidium parvum hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Candida albicans second truncated form of RIM11 Serine/threonine protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania donovani cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase Get druggable targets OG5_127439 All targets in OG5_127439
Echinococcus multilocularis dual specificity Get druggable targets OG5_127439 All targets in OG5_127439
Echinococcus granulosus glycogen synthase kinase 3 beta Get druggable targets OG5_126888 All targets in OG5_126888
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_127439 All targets in OG5_127439
Onchocerca volvulus Get druggable targets OG5_126780 All targets in OG5_126780
Cryptosporidium hominis cdc2-like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma japonicum expressed protein Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus granulosus casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus granulosus casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma japonicum ko:K02087 cyclin-dependent kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi casein kinase 1, delta Get druggable targets OG5_126780 All targets in OG5_126780
Plasmodium vivax casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis casein kinase i Get druggable targets OG5_126780 All targets in OG5_126780
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Leishmania infantum cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CK1 family protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania braziliensis protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania donovani dual-specificity protein kinase, putative Get druggable targets OG5_127439 All targets in OG5_127439
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_127901 All targets in OG5_127901
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma cruzi CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus multilocularis casein kinase I delta Get druggable targets OG5_126780 All targets in OG5_126780
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_127439 All targets in OG5_127439
Schistosoma japonicum ko:K08959 casein kinase 1, delta, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/GSK protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Theileria parva casein kinase I, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma brucei cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans weaker similarity to S. cerevisiae YAK1 (YJL141C) Get druggable targets OG5_127439 All targets in OG5_127439
Leishmania infantum casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative Get druggable targets OG5_127439 All targets in OG5_127439
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma brucei gambiense serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Cryptosporidium hominis casein kinase i Get druggable targets OG5_126780 All targets in OG5_126780
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_127439 All targets in OG5_127439
Entamoeba histolytica casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium falciparum glycogen synthase kinase 3 Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium vivax protein kinase Crk2 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Plasmodium berghei casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma cruzi glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Giardia lamblia Kinase, CK1 Casein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania braziliensis cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis protein kinase shaggy Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania infantum protein kinase, putative,dual-specificity protein kinase, putative Get druggable targets OG5_127439 All targets in OG5_127439
Onchocerca volvulus Get druggable targets OG5_126780 All targets in OG5_126780
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trypanosoma brucei cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei casein kinase I, isoform 2 Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma congolense cdc2-related kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma japonicum ko:K02090 cyclin-dependent kinase 5, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma japonicum ko:K02218 casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/GSK protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis dual specificity Get druggable targets OG5_127439 All targets in OG5_127439
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania braziliensis cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus dual specificity Get druggable targets OG5_127901 All targets in OG5_127901
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus dual specificity Get druggable targets OG5_127439 All targets in OG5_127439
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Candida albicans Serine/threonine protein kinase required for induction of IME2 by Ime1p Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_127439 All targets in OG5_127439
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Neospora caninum hypothetical protein Get druggable targets OG5_127439 All targets in OG5_127439
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative Get druggable targets OG5_127439 All targets in OG5_127439
Giardia lamblia Kinase, CMGC GSK Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma brucei gambiense cell division protein kinase 2 homolog 1,cdc2- like protein kinase, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Babesia bovis protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium yoelii cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Babesia bovis cell division control protein 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Cryptosporidium parvum casein kinase I Get druggable targets OG5_126780 All targets in OG5_126780
Babesia bovis casein kinase I, putative Get druggable targets OG5_126780 All targets in OG5_126780
Plasmodium knowlesi glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 Get druggable targets OG5_127439 All targets in OG5_127439
Plasmodium vivax glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative Get druggable targets OG5_127439 All targets in OG5_127439
Cryptosporidium parvum Cdc2-like CDK2/CDC28 like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania infantum cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum Serine/threonine-protein kinase minibrain, putative Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium berghei glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma japonicum ko:K08825 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase, putative Get druggable targets OG5_127439 All targets in OG5_127439
Candida albicans Casein kinase I: DNA repair, meiosis Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania mexicana cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense cell division related protein kinase 2, putative,CDC2-related protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans weaker similarity to S. cerevisiae YAK1 (YJL141C) Get druggable targets OG5_127439 All targets in OG5_127439
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase Get druggable targets OG5_127901 All targets in OG5_127901
Theileria parva cell division control protein 2 related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Theileria parva glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_127439 All targets in OG5_127439
Trypanosoma brucei gambiense protein kinase, putative,dual-specificity protein kinase, putative Get druggable targets OG5_127439 All targets in OG5_127439
Leishmania infantum serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus granulosus dual specificity Get druggable targets OG5_127439 All targets in OG5_127439
Leishmania donovani cell division protein kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Casein kinase I: DNA repair, meiosis Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus granulosus protein kinase shaggy Get druggable targets OG5_126888 All targets in OG5_126888
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127439 All targets in OG5_127439
Leishmania mexicana protein kinase-like protein Get druggable targets OG5_127439 All targets in OG5_127439
Echinococcus multilocularis casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus granulosus casein kinase i Get druggable targets OG5_126780 All targets in OG5_126780
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Trypanosoma congolense serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_127439 All targets in OG5_127439
Plasmodium falciparum protein kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Neospora caninum CMGC kinase, CDK family TgPK2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma cruzi CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_127439 All targets in OG5_127439
Echinococcus granulosus casein kinase I delta Get druggable targets OG5_126780 All targets in OG5_126780
Neospora caninum hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus dual specificity Get druggable targets OG5_127439 All targets in OG5_127439
Leishmania braziliensis protein kinase, putative,dual-specificity protein kinase, putative Get druggable targets OG5_127439 All targets in OG5_127439
Echinococcus granulosus casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania major cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Neospora caninum AFL091Wp, related Get druggable targets OG5_126780 All targets in OG5_126780
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium berghei cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma cruzi casein kinase, delta isoform, putative Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative Get druggable targets OG5_127439 All targets in OG5_127439
Giardia lamblia Kinase, CMGC DYRK Get druggable targets OG5_127439 All targets in OG5_127439
Echinococcus multilocularis dual specificity Get druggable targets OG5_127439 All targets in OG5_127439
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127439 All targets in OG5_127439
Echinococcus multilocularis dual specificity Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus granulosus casein kinase I delta Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma brucei gambiense casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus granulosus cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum glycogen synthase kinase 3 Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma congolense casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) CK1/CK1 protein kinase Casein kinase I isoform alpha   125 aa 138 aa 41.3 %
Candida albicans kinase required for spore wall formation Casein kinase I isoform alpha   125 aa 106 aa 23.6 %
Loa Loa (eye worm) TKL/MLK/MLK protein kinase Casein kinase I isoform alpha   125 aa 117 aa 24.8 %
Trypanosoma congolense serine/threonine-protein kinase, putative Casein kinase I isoform alpha   125 aa 117 aa 28.2 %
Entamoeba histolytica protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 342 aa 28.1 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 128 aa 38.3 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 131 aa 31.3 %
Brugia malayi p21/Cdc42/Rac1-activated kinase Casein kinase I isoform alpha   125 aa 133 aa 27.1 %
Candida albicans Serine-threonine protein kinase similar to S. cerevisiae CMK2 (YOL016C) calcium/calmodulin-dependent protein kinase Casein kinase I isoform alpha   125 aa 131 aa 33.6 %
Trypanosoma congolense protein kinase, putative Casein kinase I isoform alpha   125 aa 115 aa 32.2 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 126 aa 35.7 %
Onchocerca volvulus EGL-17 homolog Casein kinase I isoform alpha   125 aa 112 aa 30.4 %
Plasmodium vivax calcium-dependent protein kinase 4, putative Casein kinase I isoform alpha   125 aa 130 aa 30.0 %
Trypanosoma cruzi protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 339 aa 23.3 %
Trypanosoma brucei gambiense protein kinase, putative,SNF1-related protein kinases, putative Casein kinase I isoform alpha   125 aa 112 aa 26.8 %
Onchocerca volvulus Putative nucleotide binding protein 2 Casein kinase I isoform alpha   125 aa 125 aa 26.4 %
Leishmania infantum protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 365 aa 23.6 %
Brugia malayi serine/threonine-protein kinase PAK 7 Glycogen synthase kinase 3 beta   420 aa 364 aa 25.5 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 115 aa 27.8 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 131 aa 34.4 %
Candida albicans likely protein kinase similar to S. cerevisiae IPL1 (YPL209C) Aurora protein kinase involved in regulating kinetochore-microtubu Glycogen synthase kinase 3 beta   420 aa 340 aa 25.6 %
Leishmania donovani mitogen-activated protein kinase kinase 3, putative Glycogen synthase kinase 3 beta   420 aa 349 aa 26.4 %
Trichomonas vaginalis CMGC family protein kinase Casein kinase I isoform alpha   125 aa 115 aa 27.8 %
Trypanosoma brucei gambiense protein kinase, putative,tyrosine protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 388 aa 27.6 %
Schistosoma mansoni ephrin receptor Glycogen synthase kinase 3 beta   420 aa 374 aa 22.7 %
Leishmania infantum mitogen-activated protein kinase 7, putative Casein kinase I isoform alpha   125 aa 118 aa 33.1 %
Trypanosoma brucei Forkhead Kinase, putative Casein kinase I isoform alpha   125 aa 102 aa 30.4 %
Trypanosoma congolense protein kinase, putative Casein kinase I isoform alpha   125 aa 135 aa 23.0 %
Plasmodium berghei serine/threonine protein kinase KIN, putative Casein kinase I isoform alpha   125 aa 132 aa 31.8 %
Leishmania braziliensis mitogen-activated protein kinase 7, putative Casein kinase I isoform alpha   125 aa 120 aa 31.7 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 55.7 %
Leishmania major protein kinase-like protein Casein kinase I isoform alpha   125 aa 133 aa 28.6 %
Echinococcus multilocularis tyrosine protein kinase shark Casein kinase I isoform alpha   125 aa 128 aa 26.6 %
Trypanosoma brucei gambiense protein kinase, putative Casein kinase I isoform alpha   125 aa 136 aa 23.5 %
Trypanosoma brucei protein kinase, putative Casein kinase I isoform alpha   125 aa 117 aa 29.9 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 101 aa 26.7 %
Entamoeba histolytica protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 101 aa 31.7 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 45.6 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 30.3 %
Leishmania infantum protein kinase, putative,mitogen-activated protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 379 aa 30.9 %
Leishmania infantum protein kinase, putative Casein kinase I isoform alpha   125 aa 120 aa 30.8 %
Echinococcus multilocularis tau tubulin kinase 1 Casein kinase I isoform alpha   125 aa 133 aa 36.8 %
Leishmania braziliensis protein kinase, putative,casein kinase I, putative Casein kinase I isoform alpha   125 aa 130 aa 42.3 %
Leishmania braziliensis protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 337 aa 25.5 %
Plasmodium knowlesi serine/threonine kinase-1, putative Glycogen synthase kinase 3 beta   420 aa 341 aa 24.0 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 124 aa 69.4 %
Leishmania mexicana casein kinase I, putative Casein kinase I isoform alpha   125 aa 183 aa 38.8 %
Leishmania mexicana kinase-like protein Casein kinase I isoform alpha   125 aa 104 aa 28.8 %
Trypanosoma cruzi casein kinase 1 isoform 2, putative Casein kinase I isoform alpha   125 aa 128 aa 45.3 %
Entamoeba histolytica protein kinase, putative Casein kinase I isoform alpha   125 aa 127 aa 29.1 %
Trypanosoma brucei gambiense hypothetical protein, conserved Casein kinase I isoform alpha   125 aa 101 aa 17.8 %
Trypanosoma congolense protein kinase, putative Casein kinase I isoform alpha   125 aa 121 aa 22.3 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 124 aa 58.9 %
Leishmania braziliensis protein kinase, putative Casein kinase I isoform alpha   125 aa 130 aa 32.3 %
Leishmania mexicana protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 391 aa 25.8 %
Schistosoma mansoni tyrosine kinase Casein kinase I isoform alpha   125 aa 126 aa 27.0 %
Schistosoma mansoni dual specificity kinase Casein kinase I isoform alpha   125 aa 127 aa 29.9 %
Leishmania donovani protein kinase-like protein Casein kinase I isoform alpha   125 aa 133 aa 28.6 %
Leishmania donovani protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 337 aa 22.8 %
Trichomonas vaginalis STE family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 30.4 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 132 aa 27.3 %
Leishmania mexicana protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 390 aa 22.3 %
Trichomonas vaginalis TKL family protein kinase Casein kinase I isoform alpha   125 aa 126 aa 27.0 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 109 aa 25.7 %
Loa Loa (eye worm) TK/FER protein kinase Casein kinase I isoform alpha   125 aa 131 aa 27.5 %
Brugia malayi hypothetical protein Casein kinase I isoform alpha   125 aa 108 aa 24.1 %
Giardia lamblia Kinase, NEK Casein kinase I isoform alpha   125 aa 123 aa 26.0 %
Babesia bovis PK4 protein kinase Casein kinase I isoform alpha   125 aa 124 aa 28.2 %
Neospora caninum Casein kinase one (CK1), putative Casein kinase I isoform alpha   125 aa 125 aa 58.4 %
Echinococcus multilocularis serine:threonine protein kinase MARK2 Casein kinase I isoform alpha   125 aa 131 aa 29.0 %
Loa Loa (eye worm) WNK protein kinase Casein kinase I isoform alpha   125 aa 107 aa 28.0 %
Schistosoma japonicum ko:K00924 G-protein-coupled Receptor Kinase [EC:2.7.1.-], putative Casein kinase I isoform alpha   125 aa 109 aa 25.7 %
Entamoeba histolytica protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 119 aa 32.8 %
Loa Loa (eye worm) CK1/TTBK protein kinase Casein kinase I isoform alpha   125 aa 126 aa 37.3 %
Onchocerca volvulus Serine\/threonine-protein kinase par-1 homolog Casein kinase I isoform alpha   125 aa 132 aa 28.8 %
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 Glycogen synthase kinase 3 beta   420 aa 373 aa 26.0 %
Echinococcus multilocularis aurora kinase A Casein kinase I isoform alpha   125 aa 124 aa 30.6 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 124 aa 30.6 %
Candida albicans kinase required for late nuclear division Glycogen synthase kinase 3 beta   420 aa 363 aa 23.4 %
Leishmania donovani Wee1-like protein kinase, putative Casein kinase I isoform alpha   125 aa 115 aa 27.0 %
Plasmodium berghei serine/threonine protein kinase, putative Casein kinase I isoform alpha   125 aa 127 aa 25.2 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 130 aa 33.8 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 32.8 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 118 aa 33.1 %
Echinococcus multilocularis serine:threonine protein kinase 12 B Casein kinase I isoform alpha   125 aa 116 aa 31.9 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 124 aa 24.2 %
Schistosoma japonicum ko:K08823 CDC-like kinase, putative Glycogen synthase kinase 3 beta   420 aa 404 aa 20.8 %
Plasmodium knowlesi serine/threonine protein kinase, putative Casein kinase I isoform alpha   125 aa 125 aa 24.8 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 124 aa 57.3 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 36.9 %
Trichomonas vaginalis STE family protein kinase Casein kinase I isoform alpha   125 aa 123 aa 29.3 %
Candida albicans kinase required for spore wall formation Casein kinase I isoform alpha   125 aa 106 aa 23.6 %
Schistosoma japonicum ko:K05703 proto-oncogene tyrosine-protein kinase Fyn, putative Casein kinase I isoform alpha   125 aa 122 aa 27.0 %
Candida albicans Cyclin-dependent serine/threonin protein kinase Glycogen synthase kinase 3 beta   420 aa 352 aa 25.6 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 130 aa 26.9 %
Loa Loa (eye worm) STE/STE20/KHS protein kinase Casein kinase I isoform alpha   125 aa 101 aa 26.7 %
Leishmania donovani protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 353 aa 24.4 %
Trypanosoma congolense kinetoplastid kinetochore protein 3, putative Casein kinase I isoform alpha   125 aa 124 aa 30.6 %
Trypanosoma congolense Mitogen-activated protein kinase 8, putative Casein kinase I isoform alpha   125 aa 127 aa 27.6 %
Giardia lamblia Kinase, AGC MAST Casein kinase I isoform alpha   125 aa 133 aa 30.1 %
Schistosoma japonicum ko:K08282 non-specific serine/threonine protein kinase [EC2.7.11.1], putative Casein kinase I isoform alpha   125 aa 114 aa 25.4 %
Trichomonas vaginalis AGC family protein kinase Casein kinase I isoform alpha   125 aa 123 aa 30.1 %
Trichomonas vaginalis CMGC family protein kinase Casein kinase I isoform alpha   125 aa 131 aa 32.8 %
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative Casein kinase I isoform alpha   125 aa 129 aa 31.0 %
Leishmania infantum serine/threonine-protein kinase, putative,protein kinase, putative Casein kinase I isoform alpha   125 aa 115 aa 27.0 %
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative Casein kinase I isoform alpha   125 aa 135 aa 24.4 %
Trypanosoma cruzi casein kinase I, putative Casein kinase I isoform alpha   125 aa 131 aa 48.1 %
Leishmania donovani mitogen-activated protein kinase 7, putative Casein kinase I isoform alpha   125 aa 118 aa 33.1 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 127 aa 26.8 %
Trypanosoma congolense kinetoplastid kinetochore protein, putative Glycogen synthase kinase 3 beta   420 aa 406 aa 22.2 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 121 aa 25.6 %
Loa Loa (eye worm) CK1/WORM6 protein kinase Casein kinase I isoform alpha   125 aa 124 aa 33.1 %
Trypanosoma cruzi Atypical serine/threonine protein kinase BUD32, putative Casein kinase I isoform alpha   125 aa 114 aa 23.7 %
Schistosoma japonicum Serine/threonine-protein kinase Chk1, putative Glycogen synthase kinase 3 beta   420 aa 338 aa 25.7 %
Trypanosoma cruzi tyrosine protein kinase, putative Casein kinase I isoform alpha   125 aa 137 aa 28.5 %
Loa Loa (eye worm) CK1/TTBKL protein kinase Casein kinase I isoform alpha   125 aa 130 aa 32.3 %
Loa Loa (eye worm) CK1/TTBKL protein kinase Casein kinase I isoform alpha   125 aa 127 aa 28.3 %
Trypanosoma cruzi tyrosine protein kinase, putative Casein kinase I isoform alpha   125 aa 137 aa 28.5 %
Schistosoma mansoni tyrosine kinase Casein kinase I isoform alpha   125 aa 126 aa 27.8 %
Candida albicans probable Ser Thr protein kinase, similar to RCK2 Glycogen synthase kinase 3 beta   420 aa 384 aa 22.7 %
Trypanosoma brucei gambiense protein kinase, putative Casein kinase I isoform alpha   125 aa 102 aa 30.4 %
Leishmania mexicana protein kinase, putative Casein kinase I isoform alpha   125 aa 120 aa 30.0 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 136 aa 25.7 %
Theileria parva protein kinase, putative Casein kinase I isoform alpha   125 aa 127 aa 27.6 %
Echinococcus granulosus calcium:calmodulin dependent protein kinase type Casein kinase I isoform alpha   125 aa 127 aa 28.3 %
Schistosoma mansoni tyrosine kinase Casein kinase I isoform alpha   125 aa 115 aa 24.3 %
Leishmania mexicana serine/threonine-protein kinase, putative,protein kinase, putative Casein kinase I isoform alpha   125 aa 115 aa 27.0 %
Trypanosoma congolense Protein kinase domain containing protein, putative Glycogen synthase kinase 3 beta   420 aa 346 aa 23.1 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 29.6 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 127 aa 38.6 %
Trichomonas vaginalis TKL family protein kinase Casein kinase I isoform alpha   125 aa 128 aa 25.8 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 105 aa 26.7 %
Trichomonas vaginalis TKL family protein kinase Casein kinase I isoform alpha   125 aa 112 aa 25.9 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 125 aa 25.6 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 30.4 %
Loa Loa (eye worm) STE/STE20/PAKA protein kinase Casein kinase I isoform alpha   125 aa 127 aa 27.6 %
Loa Loa (eye worm) CK1/TTBKL protein kinase Casein kinase I isoform alpha   125 aa 126 aa 29.4 %
Trypanosoma brucei gambiense protein kinase, putative,MAP kinase kinase, putative Casein kinase I isoform alpha   125 aa 108 aa 23.1 %
Plasmodium falciparum protein kinase, putative Casein kinase I isoform alpha   125 aa 113 aa 30.1 %
Trypanosoma brucei Aurora kinase 2, putative Casein kinase I isoform alpha   125 aa 130 aa 29.2 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 123 aa 38.2 %
Plasmodium falciparum serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 101 aa 31.7 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 101 aa 26.7 %
Leishmania donovani protein kinase, putative Casein kinase I isoform alpha   125 aa 117 aa 29.1 %
Loa Loa (eye worm) IRE protein kinase Casein kinase I isoform alpha   125 aa 132 aa 27.3 %
Leishmania mexicana zinc finger protein kinase-like Glycogen synthase kinase 3 beta   420 aa 347 aa 26.5 %
Schistosoma japonicum ko:K06276 3-phosphoinositide dependent protein kinase-1, putative Glycogen synthase kinase 3 beta   420 aa 339 aa 24.8 %
Candida albicans likely protein kinase similar to S. cerevisiae ATG1 (YGL180W) protein kinase required for autophagy and cytoplasm-to-vacuole tar Casein kinase I isoform alpha   125 aa 110 aa 28.2 %
Giardia lamblia Kinase, NEK Casein kinase I isoform alpha   125 aa 103 aa 28.2 %
Trichomonas vaginalis STE family protein kinase Casein kinase I isoform alpha   125 aa 107 aa 29.9 %
Leishmania infantum mitogen-activated protein kinase, putative,kinase, putative Glycogen synthase kinase 3 beta   420 aa 347 aa 32.6 %
Leishmania infantum protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 353 aa 24.4 %
Leishmania major protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 365 aa 23.3 %
Trypanosoma congolense protein kinase, putative Casein kinase I isoform alpha   125 aa 126 aa 24.6 %
Cryptosporidium hominis casein kinase I Casein kinase I isoform alpha   125 aa 127 aa 61.4 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 54.4 %
Entamoeba histolytica protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 349 aa 31.2 %
Plasmodium vivax serine/threonine-protein kinase 2, putative Casein kinase I isoform alpha   125 aa 125 aa 24.8 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 125 aa 28.8 %
Echinococcus multilocularis dual specificity Glycogen synthase kinase 3 beta   420 aa 367 aa 29.2 %
Echinococcus granulosus glycogen synthase kinase 3 Glycogen synthase kinase 3 beta   420 aa 415 aa 40.7 %
Onchocerca volvulus Probable ribosome biogenesis protein Casein kinase I isoform alpha   125 aa 114 aa 29.8 %
Cryptosporidium hominis hypothetical protein Casein kinase I isoform alpha   125 aa 107 aa 24.3 %
Trichomonas vaginalis CMGC family protein kinase Casein kinase I isoform alpha   125 aa 131 aa 29.0 %
Entamoeba histolytica protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 128 aa 25.8 %
Leishmania major protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 364 aa 25.8 %
Trypanosoma brucei rac serine-threonine kinase, putative Glycogen synthase kinase 3 beta   420 aa 342 aa 30.1 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 123 aa 33.3 %
Leishmania major protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 339 aa 26.5 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 139 aa 28.1 %
Entamoeba histolytica protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 121 aa 26.4 %
Mycobacterium leprae Probable transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A) Casein kinase I isoform alpha   125 aa 134 aa 26.9 %
Schistosoma mansoni tyrosine kinase Casein kinase I isoform alpha   125 aa 138 aa 28.3 %
Brugia malayi SH2 domain containing protein Casein kinase I isoform alpha   125 aa 124 aa 25.0 %
Trichomonas vaginalis STE family protein kinase Casein kinase I isoform alpha   125 aa 131 aa 32.1 %
Echinococcus multilocularis serine:threonine protein kinase Casein kinase I isoform alpha   125 aa 137 aa 26.3 %
Leishmania infantum protein kinase, putative,SNF1-related protein kinases, putative Casein kinase I isoform alpha   125 aa 123 aa 31.7 %
Leishmania infantum hypothetical protein, conserved Casein kinase I isoform alpha   125 aa 115 aa 27.0 %
Echinococcus granulosus beta-adrenergic receptor kinase Casein kinase I isoform alpha   125 aa 109 aa 24.8 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 123 aa 27.6 %
Trypanosoma brucei CMGC/DYRK protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 388 aa 27.6 %
Plasmodium vivax protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 119 aa 27.7 %
Leishmania mexicana protein kinase, putative Casein kinase I isoform alpha   125 aa 130 aa 31.5 %
Giardia lamblia Kinase, NEK Casein kinase I isoform alpha   125 aa 108 aa 25.9 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 48.4 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 132 aa 25.8 %
Onchocerca volvulus Tyrosine-protein phosphatase 69D homolog Casein kinase I isoform alpha   125 aa 132 aa 31.8 %
Leishmania braziliensis mitogen-activated protein kinase, putative,map kinase, putative Casein kinase I isoform alpha   125 aa 106 aa 26.4 %
Leishmania donovani Mitogen-activated protein kinase 8, putative Casein kinase I isoform alpha   125 aa 106 aa 25.5 %
Echinococcus granulosus serine/threonine protein kinase Glycogen synthase kinase 3 beta   420 aa 393 aa 25.4 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 39.3 %
Plasmodium berghei protein kinase 2 Casein kinase I isoform alpha   125 aa 125 aa 24.8 %
Leishmania major protein kinase, putative,casein kinase I, putative Casein kinase I isoform alpha   125 aa 130 aa 44.6 %
Trypanosoma brucei gambiense casein kinase 1, putative Casein kinase I isoform alpha   125 aa 128 aa 57.0 %
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative Casein kinase I isoform alpha   125 aa 124 aa 29.8 %
Trichomonas vaginalis CMGC family protein kinase Casein kinase I isoform alpha   125 aa 135 aa 29.6 %
Plasmodium falciparum calcium-dependent protein kinase 5 Casein kinase I isoform alpha   125 aa 110 aa 28.2 %
Toxoplasma gondii protein kinase, other Glycogen synthase kinase 3 beta   420 aa 352 aa 24.7 %
Onchocerca volvulus Cdc42-interacting protein 4 homolog Casein kinase I isoform alpha   125 aa 127 aa 31.5 %
Plasmodium berghei mitogen-activated protein kinase 2 Glycogen synthase kinase 3 beta   420 aa 351 aa 30.5 %
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative Casein kinase I isoform alpha   125 aa 115 aa 26.1 %
Giardia lamblia Kinase, CMGC DYRK Casein kinase I isoform alpha   125 aa 131 aa 26.0 %
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative Casein kinase I isoform alpha   125 aa 128 aa 23.4 %
Leishmania infantum protein kinase, putative,polo-like protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 364 aa 26.9 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 36.8 %
Cryptosporidium hominis cdc2-related protein kinase Glycogen synthase kinase 3 beta   420 aa 390 aa 27.4 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 128 aa 28.9 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 131 aa 23.7 %
Trypanosoma brucei cdc2-related protein kinase 11, putative Glycogen synthase kinase 3 beta   420 aa 385 aa 24.9 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 128 aa 27.3 %
Plasmodium berghei calcium-dependent protein kinase 4 Casein kinase I isoform alpha   125 aa 130 aa 30.0 %
Cryptosporidium parvum cdc2-related protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 390 aa 26.9 %
Babesia bovis calcium-dependent protein kinase 4 Casein kinase I isoform alpha   125 aa 128 aa 29.7 %
Cryptosporidium parvum protein kinase Glycogen synthase kinase 3 beta   420 aa 337 aa 26.4 %
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase Glycogen synthase kinase 3 beta   420 aa 369 aa 25.5 %
Leishmania major protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 432 aa 24.3 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 130 aa 33.1 %
Leishmania mexicana mitogen-activated protein kinase, putative,map kinase, putative Casein kinase I isoform alpha   125 aa 106 aa 26.4 %
Trypanosoma cruzi casein kinase, putative Casein kinase I isoform alpha   125 aa 128 aa 62.5 %
Leishmania braziliensis hypothetical protein, conserved Casein kinase I isoform alpha   125 aa 115 aa 27.8 %
Toxoplasma gondii AGC kinase Glycogen synthase kinase 3 beta   420 aa 341 aa 24.6 %
Leishmania braziliensis protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 444 aa 25.9 %
Leishmania donovani protein kinase, putative Casein kinase I isoform alpha   125 aa 104 aa 24.0 %
Leishmania infantum protein kinase-like protein Casein kinase I isoform alpha   125 aa 133 aa 28.6 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 127 aa 36.2 %
Leishmania donovani kinetoplastid kinetochore protein 2, putative Casein kinase I isoform alpha   125 aa 120 aa 30.8 %
Cryptosporidium parvum hypothetical protein Casein kinase I isoform alpha   125 aa 125 aa 29.6 %
Trypanosoma brucei mitogen-activated protein kinase kinase 5 Casein kinase I isoform alpha   125 aa 108 aa 23.1 %
Giardia lamblia Kinase, CMGC CLK Casein kinase I isoform alpha   125 aa 105 aa 26.7 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 124 aa 58.9 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 139 aa 32.4 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 111 aa 33.3 %
Echinococcus multilocularis serine:threonine protein kinase Chk2 Glycogen synthase kinase 3 beta   420 aa 395 aa 27.8 %
Leishmania major hypothetical protein, conserved Casein kinase I isoform alpha   125 aa 115 aa 27.8 %
Trypanosoma brucei SNF1-related protein kinases, putative Casein kinase I isoform alpha   125 aa 112 aa 26.8 %
Trypanosoma brucei casein kinase I, putative Casein kinase I isoform alpha   125 aa 131 aa 45.0 %
Leishmania infantum protein kinase-like protein Casein kinase I isoform alpha   125 aa 107 aa 27.1 %
Leishmania donovani protein kinase, putative Casein kinase I isoform alpha   125 aa 134 aa 26.1 %
Echinococcus granulosus serine:threonine protein kinase ULK3 Casein kinase I isoform alpha   125 aa 126 aa 31.0 %
Loa Loa (eye worm) CK1/TTBKL protein kinase Casein kinase I isoform alpha   125 aa 123 aa 31.7 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 126 aa 34.9 %
Neospora caninum CAM kinase, CDPK family CAM kinase TgTPK5, putative Glycogen synthase kinase 3 beta   420 aa 351 aa 24.2 %
Leishmania braziliensis protein kinase, putative Casein kinase I isoform alpha   125 aa 120 aa 31.7 %
Echinococcus multilocularis tyrosine protein kinase ABL1 Casein kinase I isoform alpha   125 aa 122 aa 27.9 %
Leishmania donovani protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 359 aa 24.8 %
Echinococcus granulosus serine:threonine protein kinase Chk2 Glycogen synthase kinase 3 beta   420 aa 346 aa 27.7 %
Entamoeba histolytica protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 126 aa 33.3 %
Schistosoma mansoni protein kinase Glycogen synthase kinase 3 beta   420 aa 337 aa 28.2 %
Schistosoma mansoni protein kinase Casein kinase I isoform alpha   125 aa 112 aa 28.6 %
Trypanosoma brucei gambiense protein kinase,zinc finger protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 341 aa 27.6 %
Leishmania infantum protein kinase, putative Casein kinase I isoform alpha   125 aa 104 aa 24.0 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 117 aa 27.4 %
Cryptosporidium parvum Ser/Thr protein kinase Casein kinase I isoform alpha   125 aa 129 aa 26.4 %
Trypanosoma brucei gambiense glycogen synthase kinase-3 alpha, putative Glycogen synthase kinase 3 beta   420 aa 420 aa 35.7 %
Leishmania donovani Protein kinase domain containing protein, putative Casein kinase I isoform alpha   125 aa 115 aa 27.0 %
Loa Loa (eye worm) AGC/GRK/BARK protein kinase Casein kinase I isoform alpha   125 aa 109 aa 27.5 %
Echinococcus multilocularis tyrosine protein kinase Fyn Casein kinase I isoform alpha   125 aa 125 aa 24.0 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 31.1 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 126 aa 28.6 %
Candida albicans protein kinase Glycogen synthase kinase 3 beta   420 aa 351 aa 25.9 %
Candida albicans likely protein kinase similar to S. cerevisiae ATG1 (YGL180W) protein kinase required for autophagy and cytoplasm-to-vacuole tar Casein kinase I isoform alpha   125 aa 110 aa 28.2 %
Leishmania braziliensis casein kinase 1 isoform 2, putative Casein kinase I isoform alpha   125 aa 129 aa 44.2 %
Trypanosoma brucei glycogen synthase kinase-3 alpha, putative Glycogen synthase kinase 3 beta   420 aa 420 aa 36.9 %
Leishmania infantum protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 363 aa 25.1 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 130 aa 25.4 %
Echinococcus multilocularis tau tubulin kinase 1 Casein kinase I isoform alpha   125 aa 125 aa 32.0 %
Schistosoma japonicum ko:K02211 cyclin-dependent kinase 9, putative Glycogen synthase kinase 3 beta   420 aa 337 aa 29.7 %
Trypanosoma cruzi CK1/TTBK protein kinase, putative Casein kinase I isoform alpha   125 aa 131 aa 35.1 %
Giardia lamblia Kinase, CAMK CAMKL Casein kinase I isoform alpha   125 aa 115 aa 31.3 %
Plasmodium yoelii probable serine/threonine-protein kinase 2 Casein kinase I isoform alpha   125 aa 125 aa 24.8 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 50.4 %
Entamoeba histolytica protein kinase, putative Casein kinase I isoform alpha   125 aa 109 aa 30.3 %
Trypanosoma brucei gambiense rac serine-threonine kinase, putative,protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 342 aa 30.1 %
Onchocerca volvulus Phorbol ester\/diacylglycerol-binding protein homolog Casein kinase I isoform alpha   125 aa 132 aa 28.8 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 115 aa 23.5 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 131 aa 32.8 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 118 aa 28.8 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 129 aa 30.2 %
Babesia bovis mitogen-activated protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 396 aa 28.8 %
Schistosoma mansoni protein kinase Casein kinase I isoform alpha   125 aa 133 aa 32.3 %
Leishmania donovani protein kinase, putative Casein kinase I isoform alpha   125 aa 130 aa 31.5 %
Trypanosoma cruzi glycogen synthase kinase-3 alpha, putative Glycogen synthase kinase 3 beta   420 aa 446 aa 38.6 %
Onchocerca volvulus Serine\/threonine-protein kinase par-1 homolog Casein kinase I isoform alpha   125 aa 132 aa 28.8 %
Trichomonas vaginalis CMGC family protein kinase Casein kinase I isoform alpha   125 aa 103 aa 29.1 %
Mycobacterium ulcerans serine/threonine-protein kinase transcriptional regulatory protein PknK_2 Casein kinase I isoform alpha   125 aa 123 aa 26.0 %
Toxoplasma gondii casein kinase I, putative Casein kinase I isoform alpha   125 aa 125 aa 60.8 %
Leishmania major protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 341 aa 26.7 %
Trypanosoma congolense protein kinase, putative Casein kinase I isoform alpha   125 aa 109 aa 27.5 %
Echinococcus granulosus serine:threonine protein kinase MARK2 Casein kinase I isoform alpha   125 aa 131 aa 29.0 %
Entamoeba histolytica hypothetical protein Casein kinase I isoform alpha   125 aa 134 aa 26.9 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 33.6 %
Candida albicans potential protein kinase Casein kinase I isoform alpha   125 aa 124 aa 27.4 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 126 aa 35.7 %
Trypanosoma congolense dual-specificity protein kinase, putative Casein kinase I isoform alpha   125 aa 103 aa 27.2 %
Toxoplasma gondii ULK kinase Casein kinase I isoform alpha   125 aa 124 aa 29.0 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 53.6 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 126 aa 26.2 %
Schistosoma japonicum ko:K00924 protein kinase [EC:2.7.1.-], putative Casein kinase I isoform alpha   125 aa 114 aa 28.9 %
Plasmodium falciparum calcium-dependent protein kinase 4 Casein kinase I isoform alpha   125 aa 129 aa 31.0 %
Echinococcus granulosus tyrosine protein kinase shark Casein kinase I isoform alpha   125 aa 128 aa 26.6 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 129 aa 54.3 %
Toxoplasma gondii calcium signaling protein kinase MARK, putative Casein kinase I isoform alpha   125 aa 129 aa 25.6 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 121 aa 30.6 %
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 Glycogen synthase kinase 3 beta   420 aa 385 aa 27.5 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 126 aa 34.1 %
Schistosoma japonicum Proto-oncogene tyrosine-protein kinase FYN, putative Casein kinase I isoform alpha   125 aa 122 aa 26.2 %
Schistosoma mansoni serine/threonine protein kinase Glycogen synthase kinase 3 beta   420 aa 340 aa 24.7 %
Onchocerca volvulus Abnormal oocyte homolog Casein kinase I isoform alpha   125 aa 139 aa 33.1 %
Trypanosoma cruzi casein kinase I, putative Casein kinase I isoform alpha   125 aa 126 aa 58.7 %
Trypanosoma brucei Atypical serine/threonine protein kinase BUD32, putative Casein kinase I isoform alpha   125 aa 136 aa 23.5 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 48.0 %
Schistosoma japonicum ko:K08958 casein kinase 1, gamma, putative Casein kinase I isoform alpha   125 aa 129 aa 54.3 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 53.6 %
Echinococcus multilocularis mitogen activated protein kinase kinase kinase Casein kinase I isoform alpha   125 aa 108 aa 22.2 %
Entamoeba histolytica protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 124 aa 23.4 %
Brugia malayi Protein kinase domain containing protein Glycogen synthase kinase 3 beta   420 aa 340 aa 27.4 %
Leishmania major casein kinase I, putative Casein kinase I isoform alpha   125 aa 128 aa 53.9 %
Giardia lamblia Kinase, NEK Casein kinase I isoform alpha   125 aa 109 aa 26.6 %
Leishmania braziliensis protein kinase-like protein Casein kinase I isoform alpha   125 aa 133 aa 30.8 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 119 aa 30.3 %
Leishmania infantum casein kinase 1 isoform 2, putative Casein kinase I isoform alpha   125 aa 129 aa 45.0 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 129 aa 28.7 %
Leishmania mexicana protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 365 aa 23.6 %
Echinococcus granulosus tau tubulin kinase 1 Casein kinase I isoform alpha   125 aa 133 aa 36.8 %
Leishmania donovani protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 365 aa 23.6 %
Mycobacterium ulcerans serine/threonine-protein kinase a PknA Casein kinase I isoform alpha   125 aa 134 aa 26.9 %
Leishmania infantum protein kinase, putative Casein kinase I isoform alpha   125 aa 130 aa 31.5 %
Schistosoma japonicum ko:K06070 protein kinase D, putative Casein kinase I isoform alpha   125 aa 109 aa 26.6 %
Brugia malayi leucyl-tRNA synthetase Casein kinase I isoform alpha   125 aa 102 aa 27.5 %
Echinococcus granulosus casein kinase I gamma Casein kinase I isoform alpha   125 aa 129 aa 51.9 %
Loa Loa (eye worm) TK/FER protein kinase Casein kinase I isoform alpha   125 aa 135 aa 31.1 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 33.6 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 150 aa 26.7 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 128 aa 27.3 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 104 aa 35.6 %
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 341 aa 24.0 %
Leishmania infantum protein kinase, putative,casein kinase I, putative Casein kinase I isoform alpha   125 aa 130 aa 43.8 %
Plasmodium knowlesi tyrosine kinase-like protein, putative Casein kinase I isoform alpha   125 aa 120 aa 25.0 %
Entamoeba histolytica protein kinase domain containing protein Glycogen synthase kinase 3 beta   420 aa 339 aa 29.2 %
Theileria parva calmodulin-domain protein kinase, putative Casein kinase I isoform alpha   125 aa 115 aa 27.8 %
Schistosoma japonicum ko:K08815 tau tubulin kinase, putative Casein kinase I isoform alpha   125 aa 131 aa 38.9 %
Schistosoma japonicum ko:K08825 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase, putative Casein kinase I isoform alpha   125 aa 129 aa 27.1 %
Toxoplasma gondii casein kinase I Casein kinase I isoform alpha   125 aa 125 aa 58.4 %
Leishmania mexicana mitogen-activated protein kinase, putative,kinase, putative Glycogen synthase kinase 3 beta   420 aa 353 aa 32.9 %
Plasmodium falciparum calcium-dependent protein kinase 1 Casein kinase I isoform alpha   125 aa 121 aa 28.1 %
Candida albicans protein serine/threonine kinase Casein kinase I isoform alpha   125 aa 122 aa 28.7 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 129 aa 29.5 %
Echinococcus granulosus dual specificity Glycogen synthase kinase 3 beta   420 aa 354 aa 30.5 %
Brugia malayi protein-tyrosine kinase Casein kinase I isoform alpha   125 aa 114 aa 29.8 %
Trichomonas vaginalis AGC family protein kinase Glycogen synthase kinase 3 beta   420 aa 338 aa 27.5 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 50.4 %
Trypanosoma brucei gambiense protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 385 aa 24.7 %
Schistosoma japonicum ko:K08825 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase, putative Casein kinase I isoform alpha   125 aa 107 aa 28.0 %
Plasmodium vivax calcium-dependent protein kinase 1, putative Glycogen synthase kinase 3 beta   420 aa 338 aa 25.7 %
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative Casein kinase I isoform alpha   125 aa 134 aa 25.4 %
Trypanosoma brucei CK1/TTBK protein kinase, putative Casein kinase I isoform alpha   125 aa 134 aa 33.6 %
Leishmania major mitogen-activated protein kinase 7, putative Casein kinase I isoform alpha   125 aa 118 aa 31.4 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 111 aa 27.0 %
Toxoplasma gondii aurora kinase(incomplete catalytic triad) Casein kinase I isoform alpha   125 aa 107 aa 29.0 %
Entamoeba histolytica serine/threonine-protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 367 aa 27.5 %
Trypanosoma congolense kinetoplastid kinetochore protein 10, putative Glycogen synthase kinase 3 beta   420 aa 406 aa 22.2 %
Echinococcus granulosus tau tubulin kinase 1 Casein kinase I isoform alpha   125 aa 123 aa 30.9 %
Candida albicans kinase required for late nuclear division Glycogen synthase kinase 3 beta   420 aa 363 aa 23.4 %
Leishmania infantum protein kinase, putative,dual-specificity protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 366 aa 28.1 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 121 aa 25.6 %
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 5 260 aa 307 aa 28.3 %
Entamoeba histolytica protein kinase, putative Casein kinase I isoform alpha   125 aa 113 aa 26.5 %
Onchocerca volvulus G protein-coupled receptor kinase 2 homolog Glycogen synthase kinase 3 beta   420 aa 362 aa 23.2 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 31.1 %
Loa Loa (eye worm) CAMK/PKD protein kinase Casein kinase I isoform alpha   125 aa 131 aa 28.2 %
Schistosoma mansoni protein kinase Glycogen synthase kinase 3 beta   420 aa 361 aa 50.4 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 129 aa 31.0 %
Echinococcus multilocularis serine:threonine protein kinase MARK2 Casein kinase I isoform alpha   125 aa 131 aa 25.2 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 125 aa 25.6 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 124 aa 37.9 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 107 aa 28.0 %
Trypanosoma congolense serine/threonine kinase, putative Casein kinase I isoform alpha   125 aa 136 aa 24.3 %
Trypanosoma cruzi mitogen activated protein kinase 4, putative Casein kinase I isoform alpha   125 aa 110 aa 29.1 %
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative Casein kinase I isoform alpha   125 aa 130 aa 28.5 %
Onchocerca volvulus EG:103B4.3 protein homolog Glycogen synthase kinase 3 beta   420 aa 368 aa 24.2 %
Cryptosporidium hominis mitogen-activated protein kinase 1, serine/threonine protein kinase Glycogen synthase kinase 3 beta   420 aa 346 aa 30.3 %
Leishmania braziliensis protein kinase, putative,SNF1-related protein kinases, putative Casein kinase I isoform alpha   125 aa 123 aa 34.1 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 132 aa 25.8 %
Onchocerca volvulus G protein-coupled receptor kinase 2 homolog Glycogen synthase kinase 3 beta   420 aa 362 aa 23.2 %
Schistosoma japonicum Tyrosine-protein kinase CSK, putative Casein kinase I isoform alpha   125 aa 126 aa 27.8 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 42.6 %
Babesia bovis Ser/Thr protein kinase, putative Casein kinase I isoform alpha   125 aa 102 aa 28.4 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 120 aa 27.5 %
Trypanosoma cruzi casein kinase, putative Casein kinase I isoform alpha   125 aa 128 aa 62.5 %
Schistosoma mansoni dual specificity kinase Casein kinase I isoform alpha   125 aa 136 aa 27.2 %
Plasmodium knowlesi serine/threonine protein kinase, putative Casein kinase I isoform alpha   125 aa 101 aa 31.7 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 128 aa 25.0 %
Leishmania mexicana protein kinase, putative,dual-specificity protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 367 aa 28.6 %
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative Casein kinase I isoform alpha   125 aa 130 aa 24.6 %
Schistosoma mansoni peptidase Casein kinase I isoform alpha   125 aa 128 aa 63.3 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 128 aa 28.1 %
Entamoeba histolytica protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 140 aa 22.9 %
Leishmania donovani casein kinase I, putative Casein kinase I isoform alpha   125 aa 180 aa 40.0 %
Trypanosoma brucei gambiense protein kinase, putative,casein kinase I, putative Casein kinase I isoform alpha   125 aa 131 aa 45.0 %
Plasmodium yoelii Arabidopsis thaliana At5g24810/F6A4_20 Casein kinase I isoform alpha   125 aa 103 aa 28.2 %
Neospora caninum Calmodulin-like domain protein kinase isoenzyme gamma, related Casein kinase I isoform alpha   125 aa 131 aa 31.3 %
Leishmania major mitogen-activated protein kinase, putative,map kinase, putative Casein kinase I isoform alpha   125 aa 106 aa 24.5 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 116 aa 27.6 %
Theileria parva cAMP-dependent protein kinase, putative Casein kinase I isoform alpha   125 aa 103 aa 35.9 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 103 aa 35.9 %
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr Casein kinase I isoform alpha   125 aa 122 aa 23.8 %
Trypanosoma congolense rac serine-threonine kinase, putative Glycogen synthase kinase 3 beta   420 aa 338 aa 28.7 %
Trypanosoma brucei protein kinase, putative Casein kinase I isoform alpha   125 aa 119 aa 26.9 %
Brugia malayi Variant SH3 domain containing protein Casein kinase I isoform alpha   125 aa 112 aa 25.0 %
Cryptosporidium hominis dual-specificity tyrosine-(Y)-phosphorylation regulated kinase TbPK4 Glycogen synthase kinase 3 beta   420 aa 337 aa 26.1 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 127 aa 26.8 %
Leishmania braziliensis serine/threonine-protein kinase, putative,protein kinase, putative Casein kinase I isoform alpha   125 aa 117 aa 29.1 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 135 aa 33.3 %
Entamoeba histolytica protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 386 aa 29.0 %
Plasmodium vivax mitogen-activated protein kinase 2, putative Glycogen synthase kinase 3 beta   420 aa 356 aa 30.6 %
Leishmania mexicana protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 454 aa 23.6 %
Onchocerca volvulus Serine\/threonine-protein kinase par-1 homolog Casein kinase I isoform alpha   125 aa 132 aa 28.8 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 137 aa 27.7 %
Leishmania braziliensis protein kinase, putative Casein kinase I isoform alpha   125 aa 137 aa 29.2 %
Leishmania infantum protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 341 aa 26.7 %
Cryptosporidium hominis protein kinase, related to and redundant with Elm1p and Pak1p in activating the SNF1 complex; Tos3p Casein kinase I isoform alpha   125 aa 128 aa 25.8 %
Echinococcus multilocularis beta adrenergic receptor kinase Casein kinase I isoform alpha   125 aa 109 aa 24.8 %
Plasmodium vivax serine/threonine protein kinase, putative Casein kinase I isoform alpha   125 aa 101 aa 31.7 %
Echinococcus granulosus phosphorylase kinase gamma subunit Casein kinase I isoform alpha   125 aa 130 aa 26.9 %
Candida albicans protein kinase Glycogen synthase kinase 3 beta   420 aa 360 aa 25.6 %
Neospora caninum hypothetical protein Casein kinase I isoform alpha   125 aa 139 aa 30.9 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 102 aa 36.3 %
Plasmodium yoelii serine/threonine-protein kinase Casein kinase I isoform alpha   125 aa 132 aa 31.8 %
Trypanosoma congolense protein kinase, putative Casein kinase I isoform alpha   125 aa 128 aa 29.7 %
Trichomonas vaginalis AGC family protein kinase Glycogen synthase kinase 3 beta   420 aa 350 aa 24.0 %
Echinococcus multilocularis phosphorylase kinase gamma subunit Casein kinase I isoform alpha   125 aa 130 aa 27.7 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 123 aa 22.0 %
Candida albicans likely protein kinase similar to S. cerevisiae IPL1 (YPL209C) Aurora protein kinase involved in regulating kinetochore-microtubu Glycogen synthase kinase 3 beta   420 aa 340 aa 25.6 %
Leishmania braziliensis casein kinase II, alpha chain, putative Casein kinase I isoform alpha   125 aa 119 aa 25.2 %
Cryptosporidium parvum casein kinase I Casein kinase I isoform alpha   125 aa 127 aa 61.4 %
Plasmodium yoelii calmodulin-domain protein kinase Casein kinase I isoform alpha   125 aa 130 aa 30.0 %
Echinococcus granulosus serine:threonine protein kinase 12 B Casein kinase I isoform alpha   125 aa 116 aa 31.9 %
Trypanosoma brucei casein kinase I isoform 1 Casein kinase I isoform alpha   125 aa 130 aa 59.2 %
Plasmodium yoelii serine/threonine-protein kinase ipl1 Casein kinase I isoform alpha   125 aa 101 aa 31.7 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 103 aa 33.0 %
Onchocerca volvulus Glycogen synthase kinase 3 beta   420 aa 340 aa 27.4 %
Leishmania donovani SNF1-related protein kinases, putative Casein kinase I isoform alpha   125 aa 123 aa 31.7 %
Leishmania major protein kinase, putative Casein kinase I isoform alpha   125 aa 104 aa 23.1 %
Echinococcus multilocularis glycogen synthase kinase 3 Glycogen synthase kinase 3 beta   420 aa 415 aa 40.7 %
Candida albicans potential protein kinase similar to A.nidulans gene (sepH) required for septation in cytokinesis Casein kinase I isoform alpha   125 aa 107 aa 26.2 %
Trypanosoma cruzi polo-like protein kinase, putative Casein kinase I isoform alpha   125 aa 117 aa 22.2 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 128 aa 29.7 %
Cryptosporidium parvum OSK4, putative Casein kinase I isoform alpha   125 aa 127 aa 28.3 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 131 aa 26.7 %
Trypanosoma congolense protein kinase, putative Casein kinase I isoform alpha   125 aa 116 aa 31.9 %
Neospora caninum protein kinase, putative Casein kinase I isoform alpha   125 aa 129 aa 25.6 %
Loa Loa (eye worm) CK1 protein kinase Casein kinase I isoform alpha   125 aa 127 aa 31.5 %
Loa Loa (eye worm) TK/FER protein kinase Casein kinase I isoform alpha   125 aa 137 aa 27.7 %
Trypanosoma brucei gambiense protein kinase, putative Casein kinase I isoform alpha   125 aa 135 aa 23.7 %
Leishmania mexicana protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 361 aa 24.4 %
Echinococcus granulosus titin Casein kinase I isoform alpha   125 aa 117 aa 25.6 %
Echinococcus multilocularis serine threonine protein kinase Casein kinase I isoform alpha   125 aa 127 aa 40.2 %
Cryptosporidium parvum MAPK, putative Casein kinase I isoform alpha   125 aa 104 aa 28.8 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 114 aa 25.4 %
Trypanosoma cruzi kinetoplastid kinetochore protein 2, putative Casein kinase I isoform alpha   125 aa 128 aa 25.0 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 128 aa 33.6 %
Candida albicans protein threonine/tyrosine kinase Glycogen synthase kinase 3 beta   420 aa 348 aa 26.1 %
Brugia malayi Ribonuclease 2-5A family protein Casein kinase I isoform alpha   125 aa 136 aa 28.7 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 34.4 %
Plasmodium falciparum mitogen-activated protein kinase 2 Glycogen synthase kinase 3 beta   420 aa 378 aa 29.4 %
Toxoplasma gondii CAM kinase, SNF1 family Casein kinase I isoform alpha   125 aa 139 aa 30.9 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 32.8 %
Echinococcus granulosus serine threonine protein kinase Casein kinase I isoform alpha   125 aa 127 aa 40.2 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 124 aa 27.4 %
Entamoeba histolytica casein kinase, putative Casein kinase I isoform alpha   125 aa 129 aa 51.2 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 132 aa 28.8 %
Entamoeba histolytica protein kinase, putative Casein kinase I isoform alpha   125 aa 137 aa 27.7 %
Leishmania donovani dual-specificity protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 366 aa 28.4 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 123 aa 56.9 %
Plasmodium falciparum protein kinase 2 Casein kinase I isoform alpha   125 aa 125 aa 24.8 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 127 aa 31.5 %
Leishmania donovani serine/threonine kinase, putative Casein kinase I isoform alpha   125 aa 107 aa 27.1 %
Leishmania mexicana protein kinase, putative Casein kinase I isoform alpha   125 aa 123 aa 30.9 %
Leishmania mexicana protein kinase, putative,casein kinase I, putative Casein kinase I isoform alpha   125 aa 130 aa 43.8 %
Echinococcus granulosus serine:threonine protein kinase ULK2 Glycogen synthase kinase 3 beta   420 aa 337 aa 25.2 %
Candida albicans protein kinase Glycogen synthase kinase 3 beta   420 aa 351 aa 25.9 %
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative Casein kinase I isoform alpha   125 aa 117 aa 29.9 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 60.0 %
Trypanosoma brucei gambiense protein kinase, putative,glycogen synthase kinase, putative Casein kinase I isoform alpha   125 aa 119 aa 26.9 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 124 aa 31.5 %
Trypanosoma congolense SNF1-related protein kinases, putative Casein kinase I isoform alpha   125 aa 114 aa 29.8 %
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 349 aa 25.2 %
Trichomonas vaginalis AGC family protein kinase Casein kinase I isoform alpha   125 aa 131 aa 29.8 %
Leishmania donovani casein kinase 1 isoform 2, putative Casein kinase I isoform alpha   125 aa 129 aa 45.0 %
Leishmania mexicana protein kinase, putative,mitogen-activated protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 384 aa 29.4 %
Toxoplasma gondii Wee kinase Casein kinase I isoform alpha   125 aa 135 aa 25.9 %
Trypanosoma congolense casein kinase I, epsilon isoform, putative Casein kinase I isoform alpha   125 aa 129 aa 55.0 %
Schistosoma japonicum ko:K08805 doublecortin and CaM kinase-like 1, putative Glycogen synthase kinase 3 beta   420 aa 342 aa 23.1 %
Candida albicans hypothetical protein Casein kinase I isoform alpha   125 aa 124 aa 27.4 %
Trichomonas vaginalis CMGC family protein kinase Casein kinase I isoform alpha   125 aa 113 aa 28.3 %
Candida albicans protein serine/threonine kinase Casein kinase I isoform alpha   125 aa 111 aa 27.0 %
Schistosoma japonicum ko:K07198 5'-AMP-activated protein kinase, catalytic alpha subunit, putative Casein kinase I isoform alpha   125 aa 111 aa 27.9 %
Echinococcus granulosus dual specificity Glycogen synthase kinase 3 beta   420 aa 344 aa 29.9 %
Echinococcus multilocularis casein kinase I gamma Casein kinase I isoform alpha   125 aa 129 aa 51.9 %
Schistosoma mansoni tyrosine kinase Casein kinase I isoform alpha   125 aa 139 aa 28.1 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 61.6 %
Entamoeba histolytica tyrosine kinase, putative Casein kinase I isoform alpha   125 aa 110 aa 24.5 %
Candida albicans similar to S. cerevisiae protein kinases PKH1 (YDR490C) and PKH2 (YOL100W) involved in MAPKKK cascade Casein kinase I isoform alpha   125 aa 132 aa 25.8 %
Giardia lamblia Kinase, NEK Glycogen synthase kinase 3 beta   420 aa 337 aa 24.3 %
Loa Loa (eye worm) CDC7 protein kinase Casein kinase I isoform alpha   125 aa 104 aa 35.6 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 120 aa 33.3 %
Schistosoma japonicum ko:K08798 MAP/microtubule affinity-regulating kinase, putative Casein kinase I isoform alpha   125 aa 132 aa 25.8 %
Plasmodium knowlesi protein kinase, putative Casein kinase I isoform alpha   125 aa 107 aa 24.3 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 128 aa 27.3 %
Leishmania major protein kinase, putative Casein kinase I isoform alpha   125 aa 120 aa 30.0 %
Trypanosoma cruzi Aurora kinase 2, putative Casein kinase I isoform alpha   125 aa 112 aa 25.0 %
Leishmania mexicana protein kinase, putative Casein kinase I isoform alpha   125 aa 133 aa 26.3 %
Schistosoma japonicum ko:K08852 endoplasmic reticulum to nucleus signalling IRE, putative Casein kinase I isoform alpha   125 aa 125 aa 21.6 %
Trypanosoma brucei gambiense casein kinase I, epsilon isoform, putative Casein kinase I isoform alpha   125 aa 130 aa 59.2 %
Trichomonas vaginalis CAMK family protein kinase Glycogen synthase kinase 3 beta   420 aa 376 aa 26.1 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 123 aa 43.9 %
Leishmania mexicana protein kinase, putative Casein kinase I isoform alpha   125 aa 117 aa 29.1 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 126 aa 35.7 %
Leishmania donovani protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 356 aa 27.5 %
Schistosoma japonicum ko:K02211 cyclin-dependent kinase 9, putative Glycogen synthase kinase 3 beta   420 aa 337 aa 29.4 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 33.6 %
Trichomonas vaginalis CMGC family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 30.4 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 124 aa 58.9 %
Trypanosoma cruzi SNF1-related protein kinases, putative Casein kinase I isoform alpha   125 aa 126 aa 27.8 %
Trypanosoma congolense serine/threonine protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 378 aa 23.8 %
Trypanosoma cruzi casein kinase, putative Casein kinase I isoform alpha   125 aa 128 aa 62.5 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 43.4 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 36.9 %
Echinococcus multilocularis CDC7 cell division cycle 7 Casein kinase I isoform alpha   125 aa 104 aa 31.7 %
Schistosoma japonicum Glycogen synthase kinase-3 alpha, putative Glycogen synthase kinase 3 beta   420 aa 430 aa 38.4 %
Leishmania braziliensis protein kinase, putative Casein kinase I isoform alpha   125 aa 116 aa 31.0 %
Plasmodium berghei serine/threonine protein kinase, putative Casein kinase I isoform alpha   125 aa 101 aa 31.7 %
Candida albicans Serine-threonine protein kinase similar to S. cerevisiae CMK2 (YOL016C) calcium/calmodulin-dependent protein kinase Casein kinase I isoform alpha   125 aa 131 aa 33.6 %
Plasmodium falciparum serine/threonine protein kinase, putative Casein kinase I isoform alpha   125 aa 124 aa 25.8 %
Leishmania infantum protein kinase, putative Casein kinase I isoform alpha   125 aa 134 aa 26.1 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 111 aa 28.8 %
Trichomonas vaginalis CMGC family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 23.0 %
Trypanosoma cruzi calcium/calmodulin-dependent protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 349 aa 24.9 %
Neospora caninum Casein kinase one (CK1) TgCK1b, putative Casein kinase I isoform alpha   125 aa 125 aa 63.2 %
Schistosoma mansoni kinase Casein kinase I isoform alpha   125 aa 128 aa 64.1 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 101 aa 24.8 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 38.4 %
Onchocerca volvulus SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 homolog Casein kinase I isoform alpha   125 aa 130 aa 42.3 %
Babesia bovis protein kinase domain containing protein Glycogen synthase kinase 3 beta   420 aa 352 aa 24.4 %
Echinococcus granulosus serine:threonine protein kinase MARK2 Casein kinase I isoform alpha   125 aa 131 aa 24.4 %
Entamoeba histolytica protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 349 aa 26.9 %
Echinococcus granulosus 5' AMP activated protein kinase catalytic Casein kinase I isoform alpha   125 aa 112 aa 28.6 %
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase Casein kinase I isoform alpha   125 aa 129 aa 23.3 %
Leishmania mexicana protein kinase-like protein Casein kinase I isoform alpha   125 aa 102 aa 24.5 %
Trypanosoma congolense protein kinase, putative Casein kinase I isoform alpha   125 aa 133 aa 31.6 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 139 aa 29.5 %
Echinococcus multilocularis serine:threonine protein kinase NLK Glycogen synthase kinase 3 beta   420 aa 395 aa 31.9 %
Trypanosoma brucei gambiense protein kinase, putative Casein kinase I isoform alpha   125 aa 134 aa 33.6 %
Leishmania major protein kinase, putative Casein kinase I isoform alpha   125 aa 117 aa 29.1 %
Schistosoma mansoni serine/threonine protein kinase Glycogen synthase kinase 3 beta   420 aa 366 aa 24.9 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 128 aa 53.1 %
Trichomonas vaginalis AGC family protein kinase Casein kinase I isoform alpha   125 aa 106 aa 26.4 %
Trypanosoma cruzi kinetoplastid kinetochore protein 3, putative Casein kinase I isoform alpha   125 aa 123 aa 30.1 %
Cryptosporidium hominis mitogen-activated protein kinase 2 Glycogen synthase kinase 3 beta   420 aa 398 aa 28.4 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 136 aa 25.7 %
Leishmania infantum mitogen-activated protein kinase, putative,map kinase, putative Casein kinase I isoform alpha   125 aa 106 aa 25.5 %
Loa Loa (eye worm) CK1 protein kinase Casein kinase I isoform alpha   125 aa 126 aa 30.2 %
Candida albicans similar to C terminus of S. cerevisiae YAK1 (YJL141C) serine-threonine protein kinase Casein kinase I isoform alpha   125 aa 123 aa 30.1 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 109 aa 30.3 %
Candida albicans second casein kinase I-like orf Casein kinase I isoform alpha   125 aa 125 aa 54.4 %
Neospora caninum CBL-interacting protein kinase 25, related Casein kinase I isoform alpha   125 aa 125 aa 28.8 %
Plasmodium vivax rac-beta serine/threonine protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 340 aa 25.0 %
Cryptosporidium hominis MAPK Casein kinase I isoform alpha   125 aa 104 aa 28.8 %
Giardia lamblia Kinase, NEK Casein kinase I isoform alpha   125 aa 104 aa 27.9 %
Leishmania major casein kinase 1 isoform 2, putative Casein kinase I isoform alpha   125 aa 129 aa 43.4 %
Schistosoma japonicum ko:K08817 cell cycle related kinase, putative Casein kinase I isoform alpha   125 aa 107 aa 23.4 %
Trichomonas vaginalis CMGC family protein kinase Casein kinase I isoform alpha   125 aa 107 aa 29.9 %
Schistosoma japonicum ko:K08253 non-specific protein-tyrosine kinase [EC2.7.10.2], putative Casein kinase I isoform alpha   125 aa 126 aa 27.0 %
Candida albicans protein serine/threonine kinase Casein kinase I isoform alpha   125 aa 111 aa 27.0 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 124 aa 51.6 %
Plasmodium knowlesi serine/threonine protein kinase, putative Casein kinase I isoform alpha   125 aa 119 aa 27.7 %
Giardia lamblia Kinase, NEK Casein kinase I isoform alpha   125 aa 129 aa 25.6 %
Onchocerca volvulus Nuclear protein UKp68 homolog Casein kinase I isoform alpha   125 aa 128 aa 27.3 %
Leishmania infantum protein kinase, putative Casein kinase I isoform alpha   125 aa 117 aa 29.1 %
Babesia bovis protein serine/threonine kinase 1 Glycogen synthase kinase 3 beta   420 aa 338 aa 23.1 %
Neospora caninum CMGC kinase, MAPK family, putative Glycogen synthase kinase 3 beta   420 aa 375 aa 31.2 %
Schistosoma japonicum ko:K08825 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase, putative Casein kinase I isoform alpha   125 aa 136 aa 27.2 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 36.1 %
Candida albicans protein kinase Glycogen synthase kinase 3 beta   420 aa 360 aa 25.6 %
Cryptosporidium parvum protein kinase Casein kinase I isoform alpha   125 aa 107 aa 24.3 %
Echinococcus multilocularis dual specificity Glycogen synthase kinase 3 beta   420 aa 397 aa 29.0 %
Schistosoma japonicum Casein kinase I isoform alpha, putative Casein kinase I isoform alpha   125 aa 128 aa 64.1 %
Trichomonas vaginalis TKL family protein kinase Casein kinase I isoform alpha   125 aa 108 aa 27.8 %
Trichomonas vaginalis CAMK family protein kinase Glycogen synthase kinase 3 beta   420 aa 363 aa 26.2 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 135 aa 49.6 %
Trypanosoma brucei casein kinase 1, putative Casein kinase I isoform alpha   125 aa 128 aa 57.0 %
Neospora caninum hypothetical protein Casein kinase I isoform alpha   125 aa 127 aa 23.6 %
Toxoplasma gondii calcium-dependent protein kinase CDPK9 Casein kinase I isoform alpha   125 aa 125 aa 26.4 %
Echinococcus multilocularis 5' AMP activated protein kinase catalytic Casein kinase I isoform alpha   125 aa 112 aa 28.6 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 55.2 %
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative Glycogen synthase kinase 3 beta   420 aa 375 aa 31.5 %
Leishmania infantum protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 380 aa 24.2 %
Neospora caninum AGC kinase, putative Glycogen synthase kinase 3 beta   420 aa 341 aa 24.6 %
Echinococcus granulosus dual specificity Glycogen synthase kinase 3 beta   420 aa 367 aa 29.4 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 128 aa 53.1 %
Echinococcus multilocularis dual specificity Glycogen synthase kinase 3 beta   420 aa 354 aa 30.5 %
Mycobacterium tuberculosis Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A) Casein kinase I isoform alpha   125 aa 134 aa 27.6 %
Schistosoma mansoni serine/threonine protein kinase Glycogen synthase kinase 3 beta   420 aa 405 aa 22.5 %
Loa Loa (eye worm) CK1/WORM6 protein kinase Casein kinase I isoform alpha   125 aa 131 aa 30.5 %
Echinococcus granulosus serine:threonine protein kinase NLK Glycogen synthase kinase 3 beta   420 aa 395 aa 31.9 %
Onchocerca volvulus Serine\/threonine-protein kinase par-1 homolog Casein kinase I isoform alpha   125 aa 132 aa 28.8 %
Leishmania donovani protein kinase, putative Casein kinase I isoform alpha   125 aa 127 aa 29.9 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 125 aa 85.6 %
Loa Loa (eye worm) TK protein kinase Casein kinase I isoform alpha   125 aa 114 aa 29.8 %
Leishmania donovani casein kinase I, putative Casein kinase I isoform alpha   125 aa 130 aa 43.8 %
Candida albicans second casein kinase I-like orf Casein kinase I isoform alpha   125 aa 125 aa 54.4 %
Neospora caninum hypothetical protein Casein kinase I isoform alpha   125 aa 115 aa 30.4 %
Trypanosoma brucei Serine/threonine-protein kinase NEK14, putative Casein kinase I isoform alpha   125 aa 117 aa 26.5 %
Schistosoma japonicum Casein kinase I isoform alpha, putative Casein kinase I isoform alpha   125 aa 128 aa 63.3 %
Echinococcus multilocularis tyrosine protein kinase Fgr Casein kinase I isoform alpha   125 aa 122 aa 23.8 %
Loa Loa (eye worm) CK1 protein kinase Casein kinase I isoform alpha   125 aa 127 aa 39.4 %
Entamoeba histolytica serine/threonine-protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 365 aa 27.9 %
Echinococcus multilocularis tyrosine protein kinase Fyn Casein kinase I isoform alpha   125 aa 115 aa 27.0 %
Trypanosoma congolense casein kinase 1, putative Casein kinase I isoform alpha   125 aa 126 aa 54.8 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 136 aa 27.9 %
Trichomonas vaginalis STE family protein kinase Glycogen synthase kinase 3 beta   420 aa 338 aa 24.3 %
Plasmodium knowlesi calcium-dependent protein kinase 4, putative Casein kinase I isoform alpha   125 aa 130 aa 30.0 %
Theileria parva 5'-AMP-activated protein kinase, putative Casein kinase I isoform alpha   125 aa 130 aa 30.0 %
Trypanosoma congolense kinetoplastid kinetochore protein 2, putative Casein kinase I isoform alpha   125 aa 118 aa 26.3 %
Trypanosoma brucei gambiense serine/threonine-protein kinase, putative,protein kinase, putative Casein kinase I isoform alpha   125 aa 130 aa 29.2 %
Onchocerca volvulus Casein kinase I homolog Casein kinase I isoform alpha   125 aa 124 aa 69.4 %
Trypanosoma cruzi casein kinase I, putative Casein kinase I isoform alpha   125 aa 131 aa 48.1 %
Entamoeba histolytica serine/threonine-protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 351 aa 28.2 %
Leishmania major protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 348 aa 24.4 %
Echinococcus granulosus peripheral plasma membrane protein CASK Glycogen synthase kinase 3 beta   420 aa 386 aa 25.1 %
Leishmania donovani protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 341 aa 26.7 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 128 aa 27.3 %
Leishmania major casein kinase I, putative Casein kinase I isoform alpha   125 aa 167 aa 44.3 %
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative Casein kinase I isoform alpha   125 aa 135 aa 23.7 %
Trypanosoma brucei hypothetical protein, conserved Casein kinase I isoform alpha   125 aa 101 aa 17.8 %
Candida albicans protein serine/threonine kinase Casein kinase I isoform alpha   125 aa 122 aa 28.7 %
Leishmania donovani protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 380 aa 23.9 %
Trypanosoma brucei gambiense protein kinase, putative Casein kinase I isoform alpha   125 aa 110 aa 30.0 %
Candida albicans potential protein kinase Casein kinase I isoform alpha   125 aa 124 aa 27.4 %
Echinococcus granulosus tyrosine protein kinase Fyn Casein kinase I isoform alpha   125 aa 125 aa 24.0 %
Leishmania donovani protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 363 aa 25.1 %
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative Casein kinase I isoform alpha   125 aa 110 aa 30.0 %
Leishmania donovani mitogen-activated protein kinase 2 Glycogen synthase kinase 3 beta   420 aa 379 aa 30.9 %
Loa Loa (eye worm) plk/plk-unclassified protein kinase Casein kinase I isoform alpha   125 aa 132 aa 31.1 %
Schistosoma mansoni serine/threonine protein kinase Glycogen synthase kinase 3 beta   420 aa 337 aa 25.8 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 124 aa 54.0 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 127 aa 32.3 %
Trypanosoma brucei gambiense protein kinase, putative Casein kinase I isoform alpha   125 aa 134 aa 25.4 %
Giardia lamblia Kinase, CDC7 Casein kinase I isoform alpha   125 aa 122 aa 31.1 %
Trypanosoma congolense protein kinase, putative Casein kinase I isoform alpha   125 aa 109 aa 26.6 %
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase Glycogen synthase kinase 3 beta   420 aa 340 aa 27.4 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 128 aa 27.3 %
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 Casein kinase I isoform alpha   125 aa 130 aa 27.7 %
Trichomonas vaginalis CMGC family protein kinase Casein kinase I isoform alpha   125 aa 126 aa 33.3 %
Leishmania braziliensis casein kinase I, putative Casein kinase I isoform alpha   125 aa 128 aa 50.0 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 131 aa 38.9 %
Echinococcus multilocularis serine:threonine protein kinase SIK3 Casein kinase I isoform alpha   125 aa 121 aa 26.4 %
Trypanosoma congolense protein kinase, putative Casein kinase I isoform alpha   125 aa 140 aa 23.6 %
Schistosoma japonicum ko:K04430 mitogen-activated protein kinase kinase 4, putative Casein kinase I isoform alpha   125 aa 102 aa 20.6 %
Leishmania donovani casein kinase I, putative Casein kinase I isoform alpha   125 aa 128 aa 53.1 %
Schistosoma mansoni protein kinase Glycogen synthase kinase 3 beta   420 aa 385 aa 29.6 %
Schistosoma mansoni tyrosine kinase Casein kinase I isoform alpha   125 aa 122 aa 29.5 %
Candida albicans similar to C terminus of S. cerevisiae YAK1 (YJL141C) serine-threonine protein kinase Casein kinase I isoform alpha   125 aa 123 aa 30.1 %
Onchocerca volvulus Putative ribose-phosphate pyrophosphokinase 1 Casein kinase I isoform alpha   125 aa 131 aa 24.4 %
Leishmania mexicana protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 437 aa 24.5 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 127 aa 26.0 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 36.1 %
Candida albicans MAPKKK essential for late nuclear division Casein kinase I isoform alpha   125 aa 107 aa 26.2 %
Trypanosoma cruzi serine/threonine-protein kinase, putative Casein kinase I isoform alpha   125 aa 112 aa 25.0 %
Entamoeba histolytica serine/threonine-protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 337 aa 26.7 %
Leishmania infantum protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 356 aa 27.5 %
Entamoeba histolytica calcium-dependent protein kinase 2, putative Casein kinase I isoform alpha   125 aa 137 aa 27.7 %
Plasmodium yoelii MORN repeat, putative Casein kinase I isoform alpha   125 aa 123 aa 20.3 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 122 aa 37.7 %
Leishmania donovani serine/threonine-protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 357 aa 23.5 %
Leishmania donovani mitogen-activated protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 347 aa 32.6 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 124 aa 56.5 %
Echinococcus multilocularis tyrosine kinase Casein kinase I isoform alpha   125 aa 143 aa 29.4 %
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative Casein kinase I isoform alpha   125 aa 112 aa 30.4 %
Entamoeba histolytica casein kinase, putative Casein kinase I isoform alpha   125 aa 127 aa 60.6 %
Toxoplasma gondii rhoptry kinase family protein ROP36 (incomplete catalytic triad) Casein kinase I isoform alpha   125 aa 102 aa 24.5 %
Plasmodium yoelii mitogen-activated protein kinase 2 Glycogen synthase kinase 3 beta   420 aa 361 aa 29.6 %
Schistosoma mansoni serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 128 aa 39.1 %
Trypanosoma congolense protein kinase, putative Casein kinase I isoform alpha   125 aa 127 aa 26.0 %
Leishmania infantum casein kinase I, putative Casein kinase I isoform alpha   125 aa 128 aa 53.1 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 126 aa 32.5 %
Leishmania braziliensis protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 361 aa 24.1 %
Giardia lamblia Kinase, NEK Casein kinase I isoform alpha   125 aa 119 aa 28.6 %
Toxoplasma gondii myosin-light-chain kinase Casein kinase I isoform alpha   125 aa 109 aa 21.1 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 127 aa 36.2 %
Leishmania infantum casein kinase I, putative Casein kinase I isoform alpha   125 aa 180 aa 40.0 %
Plasmodium knowlesi mitogen-activated protein kinase 2, putative Glycogen synthase kinase 3 beta   420 aa 361 aa 29.6 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 123 aa 30.9 %
Leishmania major protein kinase, putative Casein kinase I isoform alpha   125 aa 130 aa 31.5 %
Schistosoma japonicum Tau-tubulin kinase 1, putative Casein kinase I isoform alpha   125 aa 128 aa 38.3 %
Trypanosoma congolense protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 353 aa 21.2 %
Trichomonas vaginalis TKL family protein kinase Casein kinase I isoform alpha   125 aa 120 aa 25.8 %
Leishmania mexicana casein kinase 1 isoform 2, putative Casein kinase I isoform alpha   125 aa 129 aa 45.7 %
Echinococcus multilocularis peripheral plasma membrane protein CASK Glycogen synthase kinase 3 beta   420 aa 363 aa 25.3 %
Mycobacterium tuberculosis Probable transmembrane serine/threonine-protein kinase H PknH (protein kinase H) (STPK H) Casein kinase I isoform alpha   125 aa 127 aa 29.9 %
Leishmania braziliensis mitogen-activated protein kinase kinase 2 Casein kinase I isoform alpha   125 aa 128 aa 28.1 %
Toxoplasma gondii rhoptry protein ROP18 Glycogen synthase kinase 3 beta   420 aa 374 aa 23.0 %
Cryptosporidium parvum mitogen-activated protein kinase 1, serine/threonine protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 346 aa 30.3 %
Echinococcus multilocularis rac serine:threonine kinase Glycogen synthase kinase 3 beta   420 aa 395 aa 26.6 %
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase Casein kinase I isoform alpha   125 aa 132 aa 28.8 %
Trypanosoma congolense kinetoplastid kinetochore protein, putative Glycogen synthase kinase 3 beta   420 aa 342 aa 23.1 %
Entamoeba histolytica protein kinase, putative Casein kinase I isoform alpha   125 aa 124 aa 27.4 %
Loa Loa (eye worm) CAMK/CAMKL/SNRK protein kinase Casein kinase I isoform alpha   125 aa 137 aa 28.5 %
Plasmodium vivax tyrosine kinase-like protein, putative Casein kinase I isoform alpha   125 aa 118 aa 22.9 %
Trypanosoma cruzi casein kinase I, putative Casein kinase I isoform alpha   125 aa 126 aa 58.7 %
Candida albicans Cyclin-dependent serine/threonin protein kinase Glycogen synthase kinase 3 beta   420 aa 352 aa 25.6 %
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative Casein kinase I isoform alpha   125 aa 128 aa 32.0 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 40.8 %
Leishmania mexicana protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 352 aa 25.3 %
Trypanosoma brucei gambiense serine/threonine-protein kinase, putative Casein kinase I isoform alpha   125 aa 117 aa 26.5 %
Leishmania mexicana protein kinase-like protein Casein kinase I isoform alpha   125 aa 133 aa 27.8 %
Leishmania infantum protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 359 aa 24.8 %
Toxoplasma gondii calcium signaling protein kinase RAD53, putative Casein kinase I isoform alpha   125 aa 126 aa 29.4 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 125 aa 56.0 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 113 aa 25.7 %
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative Casein kinase I isoform alpha   125 aa 124 aa 29.8 %
Babesia bovis casein kinase II, alpha chain (CK II) Glycogen synthase kinase 3 beta   420 aa 356 aa 29.2 %
Trypanosoma brucei gambiense protein kinase, putative Casein kinase I isoform alpha   125 aa 110 aa 25.5 %
Loa Loa (eye worm) AGC/RSK/MSK protein kinase Casein kinase I isoform alpha   125 aa 125 aa 30.4 %
Neospora caninum Wee kinase, putative Casein kinase I isoform alpha   125 aa 135 aa 25.9 %
Leishmania infantum mitogen-activated protein kinase kinase 3, putative Glycogen synthase kinase 3 beta   420 aa 349 aa 26.4 %
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative Casein kinase I isoform alpha   125 aa 129 aa 27.9 %
Onchocerca volvulus Casein kinase I isoform alpha   125 aa 101 aa 34.7 %
Trypanosoma cruzi ULK family pseudokinase, putative Casein kinase I isoform alpha   125 aa 111 aa 22.5 %
Echinococcus granulosus aurora kinase A Casein kinase I isoform alpha   125 aa 124 aa 29.8 %
Candida albicans Serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 105 aa 30.5 %
Neospora caninum CAM kinase, putative Casein kinase I isoform alpha   125 aa 126 aa 28.6 %
Leishmania braziliensis protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 365 aa 23.8 %
Plasmodium knowlesi serine/threonine protein kinase KIN, putative Glycogen synthase kinase 3 beta   420 aa 390 aa 26.9 %
Entamoeba histolytica casein kinase, putative Casein kinase I isoform alpha   125 aa 121 aa 47.1 %
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase Casein kinase I isoform alpha   125 aa 125 aa 26.4 %
Brugia malayi Protein kinase domain containing protein Glycogen synthase kinase 3 beta   420 aa 368 aa 24.7 %
Trypanosoma brucei gambiense serine/threonine kinase, putative Casein kinase I isoform alpha   125 aa 129 aa 27.9 %
Leishmania infantum protein kinase-like protein Casein kinase I isoform alpha   125 aa 101 aa 24.8 %
Leishmania mexicana mitogen-activated protein kinase 7, putative Casein kinase I isoform alpha   125 aa 118 aa 32.2 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 119 aa 35.3 %
Trichomonas vaginalis CAMK family protein kinase Casein kinase I isoform alpha   125 aa 129 aa 27.1 %
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative Casein kinase I isoform alpha   125 aa 129 aa 31.0 %
Plasmodium yoelii putative protein kinase Casein kinase I isoform alpha   125 aa 105 aa 25.7 %
Candida albicans casein kinase I-like orf Casein kinase I isoform alpha   125 aa 129 aa 54.3 %
Cryptosporidium parvum mitogen-activated protein kinase 2, putative Glycogen synthase kinase 3 beta   420 aa 395 aa 28.6 %
Plasmodium berghei protein kinase, putative Casein kinase I isoform alpha   125 aa 106 aa 23.6 %
Trypanosoma brucei gambiense protein kinase, putative Casein kinase I isoform alpha   125 aa 117 aa 29.9 %
Echinococcus granulosus tyrosine protein kinase ABL1 Casein kinase I isoform alpha   125 aa 122 aa 27.9 %
Echinococcus granulosus serine:threonine protein kinase Casein kinase I isoform alpha   125 aa 137 aa 26.3 %
Trypanosoma brucei differentiation inhibitory kinase Glycogen synthase kinase 3 beta   420 aa 341 aa 27.6 %
Plasmodium yoelii serine/threonine-protein kinase, putative Casein kinase I isoform alpha   125 aa 127 aa 25.2 %
Brugia malayi Protein kinase domain containing protein Casein kinase I isoform alpha   125 aa 129 aa 24.0 %
Candida albicans probable Ser Thr protein kinase, similar to RCK2 Glycogen synthase kinase 3 beta   420 aa 384 aa 22.7 %
Leishmania infantum serine/threonine-protein kinase, putative,protein kinase, putative Glycogen synthase kinase 3 beta   420 aa 358 aa 23.7 %
Echinococcus granulosus tyrosine protein kinase Fyn Casein kinase I isoform alpha   125 aa 115 aa 27.0 %
Echinococcus granulosus serine:threonine protein kinase SIK3 Casein kinase I isoform alpha   125 aa 121 aa 27.3 %
Leishmania major mitogen-activated protein kinase kinase 2 Casein kinase I isoform alpha   125 aa 128 aa 28.1 %
Trichomonas vaginalis CK1 family protein kinase Casein kinase I isoform alpha   125 aa 121 aa 54.5 %
Leishmania mexicana casein kinase I, putative Casein kinase I isoform alpha   125 aa 128 aa 51.6 %
Toxoplasma gondii calcium-dependent protein kinase CDPK1 Casein kinase I isoform alpha   125 aa 131 aa 31.3 %
Schistosoma mansoni protein kinase Glycogen synthase kinase 3 beta   420 aa 384 aa 27.3 %
Trypanosoma cruzi cdc2-related kinase 10, putative Glycogen synthase kinase 3 beta   420 aa 381 aa 26.5 %
Echinococcus granulosus tyrosine kinase Casein kinase I isoform alpha   125 aa 143 aa 29.4 %
Trypanosoma brucei CMGC/CLK family protein kinase, putative Casein kinase I isoform alpha   125 aa 110 aa 25.5 %
Candida albicans Serine/threonine protein kinase Casein kinase I isoform alpha   125 aa 105 aa 30.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis dual specificity 0.0066 0.2548 0.2176
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0054 0.0476 0.0476
Echinococcus multilocularis dual specificity 0.0066 0.2548 0.2176
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.2548 0.2176
Plasmodium falciparum glycogen synthase kinase 3 0.006 0.149 1
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0066 0.2548 0.2176
Giardia lamblia Kinase, CMGC GSK 0.006 0.149 0.4892
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0066 0.2548 0.2176
Entamoeba histolytica protein kinase domain containing protein 0.006 0.149 0.1064
Loa Loa (eye worm) CMGC/GSK protein kinase 0.006 0.149 0.149
Giardia lamblia Kinase, CMGC DYRK 0.0066 0.2548 1
Plasmodium vivax glycogen synthase kinase 3, putative 0.006 0.149 1
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.2548 0.2176
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0054 0.0476 0.0476
Trichomonas vaginalis CMGC family protein kinase 0.006 0.149 0.4892
Onchocerca volvulus 0.006 0.149 0.5
Trichomonas vaginalis CMGC family protein kinase 0.006 0.149 0.4892
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.2548 1
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.006 0.149 0.1064
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.006 0.149 0.4892
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0066 0.2548 0.2176
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.006 0.149 0.1064
Brugia malayi intracellular kinase 0.006 0.149 0.1064
Loa Loa (eye worm) hypothetical protein 0.0107 0.9524 0.9524
Entamoeba histolytica protein kinase, putative 0.0066 0.2548 0.2176
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0066 0.2548 1
Echinococcus multilocularis dual specificity 0.0066 0.2548 0.2176
Loa Loa (eye worm) hypothetical protein 0.0107 0.9524 0.9524
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.2548 1
Trypanosoma brucei protein kinase, putative 0.006 0.149 0.1064
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0066 0.2548 0.2176
Echinococcus multilocularis protein kinase shaggy 0.006 0.149 0.1064
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.006 0.149 0.1064
Echinococcus granulosus dual specificity 0.0066 0.2548 0.2176
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0054 0.0476 0.0476
Giardia lamblia Kinase, CMGC GSK 0.006 0.149 0.4892
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.2548 1
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.2548 1
Echinococcus granulosus glycogen synthase kinase 3 beta 0.006 0.149 0.1064
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.2548 1
Echinococcus granulosus protein kinase shaggy 0.006 0.149 0.1064
Loa Loa (eye worm) CMGC/GSK protein kinase 0.006 0.149 0.149
Entamoeba histolytica protein kinase domain containing protein 0.006 0.149 0.1064
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.006 0.149 0.1064
Entamoeba histolytica protein kinase, putative 0.006 0.149 0.1064
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0066 0.2548 0.2548
Echinococcus granulosus dual specificity 0.0066 0.2548 0.2176
Trichomonas vaginalis CMGC family protein kinase 0.0066 0.2548 1
Echinococcus granulosus dual specificity 0.0066 0.2548 0.2176

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 10 uM Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]-ATP ChEMBL. 23336033
IC50 (binding) > 10 uM Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]-ATP ChEMBL. 23336033
IC50 (binding) > 10 uM Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrate ChEMBL. 23336033
IC50 (binding) > 10 uM Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrate ChEMBL. 23336033
IC50 (binding) > 10 uM Inhibition of human recombinant CDK5 ChEMBL. 23336033

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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