Detailed information for compound 1733816

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 454.435 | Formula: C18H36N2O7P2
  • H donors: 5 H acceptors: 7 LogP: 1.88 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCn1cc[n+](c1)CC(P(=O)(O)O)(P(=O)(O)[O-])O
  • InChi: 1S/C18H36N2O7P2/c1-2-3-4-5-6-7-8-9-10-11-12-13-19-14-15-20(17-19)16-18(21,28(22,23)24)29(25,26)27/h14-15,17,21H,2-13,16H2,1H3,(H3-,22,23,24,25,26,27)
  • InChiKey: CGWLEDSBGKYJGU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens farnesyl diphosphate synthase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania braziliensis farnesyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Theileria parva farnesyl pyrophosphate synthetase, putative Get druggable targets OG5_127590 All targets in OG5_127590
Trypanosoma brucei farnesyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Echinococcus granulosus farnesyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Schistosoma japonicum ko:K00787 dimethylallyltranstransferase [EC2.5.1.1], putative Get druggable targets OG5_127590 All targets in OG5_127590
Leishmania infantum farnesyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative Get druggable targets OG5_127590 All targets in OG5_127590
Candida albicans similar to S. cerevisiae ERG20 (YJL167W) farnesyl diphosphate synthetase (FPP synthetase) Get druggable targets OG5_127590 All targets in OG5_127590
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) Get druggable targets OG5_127590 All targets in OG5_127590
Leishmania mexicana farnesyl pyrophosphate synthase, putative Get druggable targets OG5_127590 All targets in OG5_127590
Toxoplasma gondii polyprenyl synthetase superfamily protein Get druggable targets OG5_127590 All targets in OG5_127590
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative Get druggable targets OG5_127590 All targets in OG5_127590
Echinococcus multilocularis farnesyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Trypanosoma cruzi farnesyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Trypanosoma congolense farnesyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative Get druggable targets OG5_127590 All targets in OG5_127590
Plasmodium berghei geranylgeranyl pyrophosphate synthase, putative Get druggable targets OG5_127590 All targets in OG5_127590
Plasmodium vivax geranylgeranyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Schistosoma mansoni farnesyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Leishmania major farnesyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative Get druggable targets OG5_127590 All targets in OG5_127590
Plasmodium yoelii farnesyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Leishmania donovani farnesyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Cryptosporidium hominis farnesyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Loa Loa (eye worm) polyprenyl synthetase Get druggable targets OG5_127590 All targets in OG5_127590
Candida albicans similar to S. cerevisiae ERG20 (YJL167W) farnesyl diphosphate synthetase (FPP synthetase) Get druggable targets OG5_127590 All targets in OG5_127590
Giardia lamblia Farnesyl diphosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Trypanosoma brucei gambiense farnesyl pyrophosphate synthase, putative Get druggable targets OG5_127590 All targets in OG5_127590
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative Get druggable targets OG5_127590 All targets in OG5_127590
Brugia malayi Polyprenyl synthetase family protein Get druggable targets OG5_127590 All targets in OG5_127590
Plasmodium knowlesi geranylgeranyl pyrophosphate synthase, putative Get druggable targets OG5_127590 All targets in OG5_127590
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
Neospora caninum hypothetical protein Get druggable targets OG5_127590 All targets in OG5_127590
Babesia bovis farnesyl pyrophosphate synthetase, putative Get druggable targets OG5_127590 All targets in OG5_127590
Cryptosporidium parvum putative farnesyl pyrophosphate synthase Get druggable targets OG5_127590 All targets in OG5_127590
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus neuropeptide receptor 0.1486 0.3213 0.3879
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0000011266 0.0000013602
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0501 0.1066 0.2007
Schistosoma mansoni protein kinase 0.0047 0.0078 0.0078
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0077 0.041
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0125 0.0249 0.0468
Onchocerca volvulus 0.0125 0.0249 0.2695
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1188 0.2563 0.3094
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Brugia malayi Serotonin receptor 0.0125 0.0249 0.0468
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0014 0.0005 0.0007
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1188 0.2563 0.3094
Echinococcus multilocularis tyrosine protein kinase csk 0.0046 0.0077 0.0093
Entamoeba histolytica hypothetical protein 0.0158 0.032 0.1718
Echinococcus granulosus tm gpcr rhodopsin 0.0125 0.0249 0.03
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0014 0.0006 0.0143
Brugia malayi hypothetical protein 0.0185 0.0378 0.0712
Loa Loa (eye worm) hypothetical protein 0.0323 0.068 0.0821
Entamoeba histolytica hypothetical protein 0.0128 0.0254 0.1361
Schistosoma mansoni tyrosine kinase 0.0367 0.0775 0.0775
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Onchocerca volvulus 0.0125 0.0249 0.2695
Loa Loa (eye worm) hypothetical protein 0.0321 0.0674 0.0814
Schistosoma mansoni tyrosine kinase 0.1188 0.2563 0.2563
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0039 0.0061 0.0115
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.1615
Loa Loa (eye worm) hypothetical protein 0.0035 0.0051 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0014 0.0005 0.001
Entamoeba histolytica BAR/SH3 domain containing protein 0.0158 0.032 0.1718
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0044 0.0774
Trypanosoma cruzi heat shock protein, putative 0.0022 0.0024 0.0413
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.001 0.0121
Mycobacterium ulcerans Type I modular polyketide synthase 0.0017 0.0013 0.016
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Schistosoma mansoni neuropeptide receptor 0.0125 0.0249 0.0249
Trypanosoma brucei heat shock protein, putative 0.0033 0.0048 0.0842
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0321 0.0674 0.0674
Onchocerca volvulus 0.0125 0.0249 0.2695
Trypanosoma cruzi heat shock protein 90, putative 0.0033 0.0048 0.0842
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0046 0.0077 0.094
Schistosoma mansoni suppressor of cytokine signaling 0.0162 0.0329 0.0329
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0018 0.0016 0.0628
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0011 0 0.0003
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0033 0.0879
Schistosoma mansoni cpg binding protein 0.0025 0.003 0.003
Echinococcus multilocularis tumor protein p63 0.0665 0.1423 0.1719
Echinococcus granulosus receptor type guanylyl cyclase 0.0046 0.0077 0.0093
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Schistosoma mansoni GTPase activating protein 0.0162 0.0329 0.0329
Trypanosoma brucei Flagellum attachment zone protein 20 0.0046 0.0077 0.1349
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Schistosoma mansoni endoplasmin 0.0033 0.0048 0.0048
Echinococcus multilocularis smad 0.0018 0.0015 0.0018
Schistosoma mansoni histamine h1 receptor 0.0125 0.0249 0.0249
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0144 1
Onchocerca volvulus 0.0162 0.0329 0.3571
Schistosoma mansoni tar DNA-binding protein 0.0173 0.0352 0.0352
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0046 0.0077 0.0077
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0209 0.043 0.052
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0048 0.0842
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0005 0.0089
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Plasmodium vivax plasmepsin V, putative 0.0185 0.0378 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0005 0.0007
Brugia malayi ecdysteroid receptor 0.0014 0.0005 0.001
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.0158 0.032 0.0387
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Echinococcus granulosus snurportin 1 0.0201 0.0413 0.0498
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0005 0.0206
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0039 0.0061 0.1077
Toxoplasma gondii histone lysine methyltransferase SET1 0.0045 0.0073 0.1046
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0077 0.094
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.001 0.0174
Echinococcus granulosus src region 0.0158 0.032 0.0387
Echinococcus multilocularis epidermal growth factor receptor 0.0126 0.0251 0.0303
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Brugia malayi Spectrin alpha chain 0.0158 0.032 0.0603
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0015 0.0009 0.0109
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0039 0.0061 0.0074
Schistosoma mansoni protein kinase 0.0046 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0011 0.0000011266 0.0000013602
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0119 0.1464
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0046 0.0077 0.0077
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0112 0.022 0.27
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0005 0.0089
Onchocerca volvulus 0.0162 0.0329 0.3571
Brugia malayi Variant SH3 domain containing protein 0.0158 0.032 0.0603
Brugia malayi RhoGAP domain containing protein 0.0162 0.0329 0.062
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.0249 0.0249
Echinococcus granulosus suppressor of cytokine signaling 6 0.0162 0.0329 0.0397
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0103 0.0124
Echinococcus multilocularis g protein coupled receptor 0.0125 0.0249 0.03
Echinococcus granulosus epidermal growth factor receptor 0.0196 0.0403 0.0486
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.0249 0.0249
Loa Loa (eye worm) TK/EGFR protein kinase 0.0196 0.0403 0.0486
Onchocerca volvulus LIM and SH3 domain protein homolog 0.0158 0.032 0.3475
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.0249 0.03
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0031 0.0044 0.0053
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0015 0.0009 0.0108
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0018 0.0016 0.0628
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Entamoeba histolytica hypothetical membrane-spanning protein 0.0128 0.0254 0.1361
Echinococcus granulosus tyrosine protein kinase Src42A 0.1188 0.2563 0.3094
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Plasmodium falciparum phd finger protein, putative 0.0018 0.0014 0.0376
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0017
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0051 0.3083
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0046 0.0077 0.1097
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0144 0.1758
Schistosoma mansoni dynamin-associated protein 0.0158 0.032 0.032
Trichomonas vaginalis hypothetical protein 0.0128 0.0254 0.3114
Echinococcus multilocularis tyrosine kinase 0.0046 0.0077 0.0093
Brugia malayi PHD-finger family protein 0.0018 0.0014 0.0027
Echinococcus granulosus peregrin 0.0018 0.0014 0.0017
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0128 0.0254 0.4479
Mycobacterium tuberculosis Probable aminotransferase 0.0112 0.022 0.8978
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0025 0.0029 0.0055
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0012 0.0003 0.0098
Schistosoma mansoni protein kinase 0.0046 0.0077 0.0077
Loa Loa (eye worm) TK protein kinase 0.0046 0.0077 0.0093
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0033 0.0879
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0125 0.0249 0.0249
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0016 0.001 0.002
Echinococcus granulosus GTP binding nuclear protein Ran 0.0014 0.0006 0.0007
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0185 0.0378 0.5411
Echinococcus granulosus tyrosine protein kinase Fyn 0.1188 0.2563 0.3094
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0031 0.0044 0.0053
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1188 0.2563 0.3094
Trypanosoma brucei ceramide phosphorylethanolamine synthase 0.0128 0.0254 0.4479
Schistosoma mansoni signal transducing adapter molecule (stam) 0.0158 0.032 0.032
Echinococcus granulosus endophilin A3 0.0158 0.032 0.0387
Schistosoma mansoni lozenge 0.0054 0.0094 0.0094
Schistosoma mansoni protein kinase 0.0047 0.0078 0.0078
Toxoplasma gondii HEAT repeat-containing protein 0.0019 0.0017 0.0236
Brugia malayi Protein kinase domain containing protein 0.0209 0.043 0.081
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0046 0.0077 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0077 0.094
Brugia malayi SH2 domain containing protein 0.0162 0.0329 0.062
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0046 0.0077 0.0093
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0162 0.0329 0.0397
Echinococcus multilocularis Aminotransferase class III 0.0016 0.001 0.0013
Schistosoma mansoni hypothetical protein 0.0125 0.0249 0.0249
Schistosoma mansoni survival motor neuron protein 0.0094 0.0181 0.0181
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0128 0.0254 0.4479
Plasmodium falciparum plasmepsin VI 0.0185 0.0378 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0015 0.0018
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0000011266 0.0000011266
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Echinococcus granulosus nostrin 0.0158 0.032 0.0387
Onchocerca volvulus 0.0162 0.0329 0.3571
Plasmodium falciparum glutathione reductase 0.0016 0.001 0.0262
Echinococcus multilocularis neuropeptides capa receptor 0.0125 0.0249 0.03
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0063 0.0114 0.0137
Loa Loa (eye worm) GMP reductase 0.0025 0.0029 0.0035
Loa Loa (eye worm) TK/EPH protein kinase 0.0046 0.0077 0.0093
Brugia malayi RNA binding protein 0.0173 0.0352 0.0662
Leishmania major hypothetical protein, conserved 0.0039 0.0061 0.1077
Onchocerca volvulus 0.0014 0.0005 0.0056
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0039 0.0061 0.0074
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0031 0.0044 0.0233
Schistosoma mansoni protein kinase 0.0046 0.0077 0.0077
Echinococcus granulosus tar DNA binding protein 0.0173 0.0352 0.0425
Echinococcus multilocularis FL cytokine receptor 0.0046 0.0077 0.0093
Entamoeba histolytica hypothetical protein 0.0046 0.0077 0.041
Schistosoma mansoni hypothetical protein 0.004 0.0063 0.0063
Brugia malayi Guanylyl cyclase protein 23 0.0046 0.0077 0.0144
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0125 0.0249 0.03
Plasmodium vivax importin-beta 2, putative 0.0019 0.0017 0.043
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Schistosoma mansoni SH2A 0.0162 0.0329 0.0329
Schistosoma mansoni endoplasmin 0.0033 0.0048 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.032 0.3927
Onchocerca volvulus 0.0046 0.0077 0.083
Loa Loa (eye worm) TK protein kinase 0.0046 0.0077 0.0093
Brugia malayi hypothetical protein 0.0125 0.0249 0.0468
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.0249 0.0249
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0039 0.0061 0.0061
Brugia malayi Variant SH3 domain containing protein 0.0158 0.032 0.0603
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0018 0.0016 0.0189
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0077 0.041
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0014 0.0005 0.0007
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0162 0.0329 0.0397
Schistosoma mansoni tyrosine kinase 0.008 0.015 0.015
Echinococcus granulosus orexin receptor type 2 0.0125 0.0249 0.03
Entamoeba histolytica hypothetical protein 0.0158 0.032 0.1718
Toxoplasma gondii protein kinase domain-containing protein 0.0046 0.0077 0.1097
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0017 0.0013 0.0532
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0162 0.0329 0.3571
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0046 0.0077 0.0093
Echinococcus granulosus activin receptor type 0.0047 0.0078 0.0094
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0104 0.0104
Echinococcus granulosus growth factor receptor bound protein 2 0.0321 0.0674 0.0814
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1188 0.2563 0.3094
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.0055 0.0096 0.2545
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0046 0.0077 0.0093
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0162 0.0329 0.0397
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0185 0.0378 0.0378
Schistosoma mansoni tar DNA-binding protein 0.0173 0.0352 0.0352
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0046 0.0077 0.083
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Loa Loa (eye worm) hypothetical protein 0.0039 0.0061 0.0074
Brugia malayi hypothetical protein 0.0125 0.0249 0.0468
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0124 0.0245 0.3007
Brugia malayi Protein kinase domain containing protein 0.0094 0.018 0.0338
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0284 0.0594 0.0718
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0174
Brugia malayi Myosin tail family protein 0.0158 0.032 0.0603
Echinococcus multilocularis SHC transforming protein 3 0.0162 0.0329 0.0397
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0128 0.0254 0.3114
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0094 0.018 0.0217
Schistosoma mansoni hypothetical protein 0.0125 0.0249 0.0249
Leishmania major hypothetical protein, conserved 0.0158 0.032 0.5651
Echinococcus granulosus activated cdc42 kinase 1 0.0046 0.0077 0.0093
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Brugia malayi Eukaryotic aspartyl protease family protein 0.0185 0.0378 0.0712
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Loa Loa (eye worm) AMP-binding enzyme family protein 0.003 0.0041 0.0049
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0124 0.0245 0.0296
Schistosoma mansoni neuropeptide F-like receptor 0.0125 0.0249 0.0249
Echinococcus granulosus ecdysone induced protein 78C 0.0014 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.0093
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0007
Trypanosoma brucei protein kinase, putative 0.0047 0.0078 0.1375
Onchocerca volvulus Fatty acid synthase homolog 0.0031 0.0044 0.047
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0011 0 0.0003
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0062
Schistosoma mansoni tensin 0.0162 0.0329 0.0329
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0014 0.0005 0.0007
Leishmania major heat shock protein, putative 0.0022 0.0024 0.0413
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0014 0.0006 0.0096
Trypanosoma brucei Heat shock protein 83, putative 0.0033 0.0048 0.0842
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Brugia malayi oxidoreductase 0.0011 0 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.0249 0.03
Toxoplasma gondii IMP dehydrogenas 0.0059 0.0104 0.1489
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Schistosoma mansoni hypothetical protein 0.0201 0.0413 0.0413
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Mycobacterium ulcerans acetyl-CoA synthetase 0.0014 0.0005 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0048 0.0842
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0000011266 0.0000013602
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Loa Loa (eye worm) glutaminase 0.0386 0.0816 0.0985
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0086 0.3488
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.0059 0.0104 0.4545
Echinococcus multilocularis carbonic anhydrase 0.0127 0.0253 0.0306
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.0055 0.0096 0.2545
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0005 0.0206
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Brugia malayi follicle stimulating hormone receptor 0.0125 0.0249 0.0468
Trypanosoma brucei polo-like protein kinase 0.0066 0.0119 0.2104
Loa Loa (eye worm) hypothetical protein 0.0127 0.0253 0.0306
Loa Loa (eye worm) hypothetical protein 0.0158 0.032 0.0387
Schistosoma mansoni sorbin 0.0158 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0077 0.0093
Schistosoma mansoni hypothetical protein 0.0158 0.032 0.032
Schistosoma mansoni tyrosine kinase 0.008 0.015 0.015
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0016 0.001 0.001
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0185 0.0378 0.0457
Loa Loa (eye worm) hypothetical protein 0.0128 0.0254 0.0307
Echinococcus granulosus jumonji domain containing protein 0.0025 0.003 0.0036
Loa Loa (eye worm) hypothetical protein 0.0501 0.1066 0.1287
Plasmodium falciparum thioredoxin reductase 0.0046 0.0075 0.1988
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0077 0.094
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0014 0.0005 0.001
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0077 0.3356
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0031 0.0044 0.0053
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0039 0.0061 0.0074
Trypanosoma brucei importin beta-1 subunit, putative 0.0019 0.0017 0.0287
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0005 0.0006
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0059 0.0104 0.1832
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0044 0.0053
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0047 0.0078 0.1118
Loa Loa (eye worm) hypothetical protein 0.0097 0.0187 0.0226
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0031 0.0044 0.0044
Brugia malayi SH2 domain containing protein 0.0162 0.0329 0.062
Plasmodium falciparum heat shock protein 90, putative 0.0019 0.0018 0.046
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0104 0.4222
Brugia malayi Variant SH3 domain containing protein 0.0162 0.0329 0.062
Onchocerca volvulus Putative GMP reductase 0.0025 0.0029 0.0312
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.001 0.0174
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.1615
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0014 0.0005 0.0062
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0075 0.1326
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.001 0.001
Entamoeba histolytica tyrosin kinase, putative 0.0046 0.0077 0.041
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0059 0.0104 0.0126
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0144 0.3794
Entamoeba histolytica hypothetical protein 0.0046 0.0077 0.041
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0162 0.0329 0.0397
Echinococcus multilocularis orexin receptor type 2 0.0125 0.0249 0.03
Schistosoma mansoni adenoreceptor 0.0125 0.0249 0.0249
Schistosoma mansoni alpha-1 adrenergic receptor 0.0125 0.0249 0.0249
Echinococcus multilocularis tyrosine protein kinase csk 0.0046 0.0077 0.0093
Toxoplasma gondii heat shock protein 75, putative 0.0022 0.0024 0.0338
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0011 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.0644 0.1379 0.1665
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0151 0.0304 0.0573
Schistosoma mansoni tyrosine kinase 0.0367 0.0775 0.0775
Loa Loa (eye worm) TK/FER protein kinase 0.0209 0.043 0.052
Schistosoma mansoni importin beta-1 0.0019 0.0017 0.0017
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Loa Loa (eye worm) TK/FER protein kinase 0.0209 0.043 0.052
Echinococcus granulosus expressed protein 0.0158 0.032 0.0387
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0066 0.0119 0.0144
Trypanosoma cruzi GMP reductase 0.0059 0.0104 0.1832
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0125 0.0249 0.0249
Brugia malayi AMP-binding enzyme family protein 0.003 0.0041 0.0076
Echinococcus granulosus g-protein coupled receptor 0.0125 0.0249 0.03
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.1077
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0061 0.1077
Loa Loa (eye worm) hypothetical protein 0.0128 0.0254 0.0307
Echinococcus multilocularis carbonic anhydrase 0.0127 0.0253 0.0306
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0014 0.0006 0.0011
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0077 0.094
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0000011266 0.0000013602
Echinococcus granulosus GPCR family 2 0.0158 0.0321 0.0387
Echinococcus granulosus natriuretic peptide receptor 1 0.0046 0.0077 0.0093
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0014 0.0005 0.0076
Entamoeba histolytica hypothetical protein 0.0119 0.0236 0.1263
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Trypanosoma cruzi polo-like protein kinase, putative 0.0066 0.0119 0.2104
Trichomonas vaginalis ran, putative 0.0014 0.0006 0.007
Trichomonas vaginalis CAMK family protein kinase 0.0033 0.0047 0.058
Schistosoma mansoni serine/threonine RGC 0.0046 0.0077 0.0077
Echinococcus multilocularis expressed conserved protein 0.0091 0.0174 0.0211
Brugia malayi Sphingomyelin synthase-related 1 0.0128 0.0254 0.0478
Mycobacterium ulcerans polyketide synthase Pks13 0.0026 0.0032 0.0389
Echinococcus multilocularis dro:myosuppressin receptor 0.0125 0.0249 0.03
Brugia malayi latrophilin 2 splice variant baaae 0.0342 0.0721 0.1358
Trypanosoma cruzi polyprenyl synthase, putative 0.0031 0.0044 0.0766
Onchocerca volvulus 0.0014 0.0005 0.0055
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0125 0.0249 0.03
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.0249 0.03
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0158 0.032 0.0387
Loa Loa (eye worm) hypothetical protein 0.0209 0.043 0.052
Toxoplasma gondii LsmAD domain-containing protein 0.0035 0.0051 0.0726
Brugia malayi putative neuropeptide receptor 0.0125 0.0249 0.0468
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0125 0.0249 0.03
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0151 0.0304 0.0368
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.032 0.3927
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0144 0.3794
Brugia malayi dehydrogenases, short chain protein 9 0.0011 0 0.0001
Onchocerca volvulus 0.0162 0.0329 0.3571
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0046 0.0077 0.0093
Schistosoma mansoni amine GPCR 0.0125 0.0249 0.0249
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0064 0.0115 0.0115
Brugia malayi larval opioid receptor 0.0125 0.0249 0.0468
Brugia malayi Tyrosine-protein kinase abl-1 0.1745 0.3778 0.7112
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0203 0.8283
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0125 0.0249 0.03
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0209 0.043 0.052
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.0249 0.0249
Brugia malayi photoreceptor-specific nuclear receptor 0.0014 0.0005 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Echinococcus multilocularis heat shock protein 0.0033 0.0048 0.0058
Echinococcus multilocularis integrin linked protein kinase 0.0046 0.0077 0.0093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.0249 0.03
Echinococcus multilocularis tyrosine protein kinase pr2 0.0046 0.0077 0.0093
Loa Loa (eye worm) hypothetical protein 0.006 0.0106 0.0128
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Onchocerca volvulus 0.003 0.0041 0.0438
Echinococcus granulosus 7tm_1 domain containing protein 0.0125 0.0249 0.03
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Schistosoma mansoni hypothetical protein 0.0342 0.0721 0.0721
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Entamoeba histolytica hypothetical protein 0.0119 0.0236 0.1263
Echinococcus granulosus tm gpcr rhodopsin 0.0125 0.0249 0.03
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0005 0.0206
Brugia malayi Importin beta-1 subunit 0.0019 0.0017 0.0031
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.0158 0.032 0.0387
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0011 0 0.0001
Brugia malayi TAR-binding protein 0.0173 0.0352 0.0662
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0046 0.0077 0.1349
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0011 0.0000011266 0.0000013602
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0077 0.041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.0249 0.0249
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.001 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.032 0.3927
Brugia malayi aspartic protease BmAsp-2, identical 0.0185 0.0378 0.0712
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0011 0.0000011266 0.0000013602
Entamoeba histolytica ankyrin repeat protein 0.0046 0.0077 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0077 0.094
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0115 0.0138
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0124 0.0245 0.3007
Loa Loa (eye worm) RNA binding protein 0.0173 0.0352 0.0425
Plasmodium falciparum protein kinase, putative 0.0046 0.0077 0.2023
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0031 0.0044 0.1148
Onchocerca volvulus 0.0434 0.0921 1
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0119 0.1464
Loa Loa (eye worm) hypothetical protein 0.0011 0.0000011266 0.0000013602
Echinococcus granulosus tyrosine protein kinase Src42A 0.0983 0.2117 0.2556
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Echinococcus multilocularis carbonic anhydrase II 0.0271 0.0567 0.0684
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0016 0.001 0.0124
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0158 0.032 0.0387
Loa Loa (eye worm) hypothetical protein 0.0047 0.0077 0.0093
Echinococcus multilocularis g protein coupled receptor 0.0125 0.0249 0.03
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0044 0.0053
Plasmodium falciparum plasmepsin II 0.0185 0.0378 1
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0187 0.1003
Entamoeba histolytica hypothetical protein 0.0128 0.0254 0.1361
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0077 0.3128
Toxoplasma gondii type I fatty acid synthase, putative 0.002 0.002 0.0283
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0005 0.0006
Brugia malayi hypothetical protein 0.0125 0.0249 0.0468
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0151 0.0304 0.0368
Echinococcus multilocularis activin receptor type 0.0047 0.0078 0.0094
Schistosoma mansoni C-fyn 0.0158 0.032 0.032
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0367 0.0775 0.0936
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0016 0.001 0.0704
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.001 0.0262
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0125 0.0249 0.03
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0039 0.0061 0.1077
Loa Loa (eye worm) TK protein kinase 0.1029 0.2218 0.2678
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0151 0.0304 0.0304
Brugia malayi sulfakinin receptor protein 0.0125 0.0249 0.0468
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0000011266 0.0000013602
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1029 0.2218 0.2678
Plasmodium vivax heat shock protein 86, putative 0.0033 0.0048 0.1262
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.0249 0.03
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0162 0.0329 0.0397
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0077 0.094
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0229 0.932
Schistosoma mansoni hypothetical protein 0.004 0.0063 0.0063
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0229 0.932
Loa Loa (eye worm) hypothetical protein 0.0121 0.0239 0.0289
Brugia malayi SH2 domain containing protein 0.0162 0.0329 0.062
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0077 0.1353
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0151 0.0304 0.0368
Leishmania major hypothetical protein, conserved 0.0039 0.0061 0.1077
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0014 0.0007 0.0295
Onchocerca volvulus 0.0125 0.0249 0.2695
Loa Loa (eye worm) hypothetical protein 0.0047 0.0077 0.0093
Schistosoma mansoni myosin xvIII 0.0125 0.0249 0.0249
Onchocerca volvulus 0.0046 0.0077 0.083
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0271 0.0567 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Trypanosoma cruzi protein kinase, putative 0.0046 0.0077 0.1349
Brugia malayi Raf kinase 0.0046 0.0077 0.0144
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.0026 0.0031
Loa Loa (eye worm) TYRA-2 protein 0.0125 0.0249 0.03
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Onchocerca volvulus 0.0047 0.0077 0.0832
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0039 0.0061 0.1077
Entamoeba histolytica hypothetical protein 0.0119 0.0236 0.1263
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0144 0.6278
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0119 0.1464
Onchocerca volvulus 0.0158 0.032 0.3475
Entamoeba histolytica hypothetical protein 0.0119 0.0236 0.1263
Trypanosoma brucei trypanothione reductase 0.0046 0.0075 0.1326
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus granulosus tensin 0.0162 0.0329 0.0397
Brugia malayi Smad1 0.0018 0.0015 0.0029
Trypanosoma brucei heat shock protein 84, putative 0.0022 0.0024 0.0413
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0094 0.0181 0.0341
Trypanosoma cruzi heat shock protein 90, putative 0.0028 0.0038 0.0657
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0271 0.0567 0.0567
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus multilocularis activated cdc42 kinase 1 0.0046 0.0077 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Schistosoma mansoni sorting nexin 0.0158 0.032 0.032
Plasmodium vivax sphingomyelin synthase 2, putative 0.0128 0.0254 0.6716
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Brugia malayi Tyrosine-protein kinase abl-1 0.2226 0.4826 0.9085
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0014 0.0005 0.0007
Brugia malayi Protein kinase domain containing protein 0.0209 0.043 0.081
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0119 0.1464
Loa Loa (eye worm) TK protein kinase 0.0046 0.0077 0.0093
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0011 0.0001 0.0011
Loa Loa (eye worm) protein kinase domain-containing protein 0.0046 0.0077 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0046 0.0077 0.0093
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0162 0.0329 0.0329
Giardia lamblia Kinase, NEK 0.0046 0.0077 0.1124
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.0249 0.03
Mycobacterium ulcerans thioesterase TesA 0.0014 0.0007 0.0083
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0028 0.0038 0.0045
Loa Loa (eye worm) hypothetical protein 0.0097 0.0188 0.0226
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0046 0.0077 0.041
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0014 0.0005 0.001
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.016 0.0325 0.0392
Schistosoma mansoni hypothetical protein 0.004 0.0063 0.0063
Loa Loa (eye worm) carbonic anhydrase 3 0.0271 0.0567 0.0684
Plasmodium vivax aspartyl protease, putative 0.0185 0.0378 1
Entamoeba histolytica hypothetical protein 0.0046 0.0077 0.041
Schistosoma mansoni transcription factor LCR-F1 0.0119 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0007
Echinococcus multilocularis peregrin 0.0018 0.0014 0.0017
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Onchocerca volvulus 0.0125 0.0249 0.2695
Onchocerca volvulus 0.0024 0.0027 0.0291
Echinococcus multilocularis transfer RNA-Ala 0.0158 0.032 0.0387
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0158 0.032 0.0387
Treponema pallidum heat shock protein 90 0.0031 0.0044 0.2498
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0323 0.068 0.0821
Brugia malayi Dehydrogenases, short chain protein 2 0.0011 0 0.0001
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0055 0.0096 0.1179
Entamoeba histolytica tyrosin kinase, putative 0.0046 0.0077 0.041
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0014 0.0376
Trypanosoma brucei heat shock protein, putative 0.0033 0.0048 0.0842
Brugia malayi jmjC domain containing protein 0.0058 0.0103 0.0194
Schistosoma mansoni hypothetical protein 0.0127 0.0253 0.0253
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0039 0.0061 0.1077
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0128 0.0254 0.4479
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Mycobacterium ulcerans Type I modular polyketide synthase 0.0017 0.0013 0.016
Brugia malayi Endoplasmin precursor 0.0033 0.0048 0.009
Schistosoma mansoni nck2/grb4 0.0321 0.0674 0.0674
Echinococcus granulosus SH2 motif 0.0162 0.0329 0.0397
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0011 0 0.0003
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0062
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0125 0.0249 0.0249
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0014 0.0005 0.0062
Echinococcus granulosus sphingomyelin synthase protein 1 0.0128 0.0254 0.0307
Echinococcus granulosus tyrosine protein kinase ABL1 0.3813 0.8283 1
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0124 0.0245 0.3007
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0321 0.0674 0.0814
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0284 0.0594 0.1119
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.001 0.0145
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0014 0.0005 0.0134
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0127 0.0253 0.0306
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0039 0.0061 0.0061
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0016 0.001 0.0124
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0046 0.0077 0.0093
Schistosoma mansoni protein kinase 0.0046 0.0077 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0014 0.0005 0.001
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0014 0.0005 0.001
Entamoeba histolytica tyrosin kinase, putative 0.0046 0.0077 0.041
Onchocerca volvulus 0.0125 0.0249 0.2695
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0059 0.0104 0.1273
Echinococcus granulosus suppressor of cytokine signaling 7 0.0162 0.0329 0.0397
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0158 0.032 0.0387
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.032 0.3927
Loa Loa (eye worm) hypothetical protein 0.0039 0.0061 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0014 0.0005 0.001
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0003
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0047 0.0078 0.1375
Schistosoma mansoni carbonic anhydrase-related 0.0127 0.0253 0.0253
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0044 0.0631
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0046 0.0077 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0185 0.0378 0.0378
Echinococcus multilocularis Smad4 0.0018 0.0015 0.0018
Onchocerca volvulus 0.0209 0.043 0.4669
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0048 0.0588
Echinococcus multilocularis ecdysone induced protein 78C 0.0014 0.0005 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Toxoplasma gondii thioredoxin reductase 0.0046 0.0075 0.1078
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.0093
Brugia malayi Dopamine receptor protein 2 0.0125 0.0249 0.0468
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0077 0.094
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0051 0.1351
Giardia lamblia Grp94/Hsp90 0.0031 0.0044 0.0636
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Loa Loa (eye worm) hypothetical protein 0.0066 0.0119 0.0144
Echinococcus granulosus neuropeptide receptor 0.0125 0.0249 0.03
Brugia malayi SH3 domain containing protein 0.0158 0.032 0.0603
Brugia malayi G-protein coupled receptor 0.0125 0.0249 0.0468
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0039 0.0061 0.1615
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0077 0.0077
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Brugia malayi Variant SH3 domain containing protein 0.0321 0.0674 0.1269
Entamoeba histolytica hypothetical protein 0.0046 0.0077 0.041
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Brugia malayi ephrin receptor 1 precursor 0.0046 0.0077 0.0144
Echinococcus multilocularis ornithine aminotransferase 0.0016 0.001 0.0013
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.001 0.0174
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0158 0.032 0.0387
Schistosoma mansoni RAR-like nuclear receptor 0.0014 0.0005 0.0005
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0039 0.0061 0.0074
Schistosoma mansoni ephrin receptor 0.0046 0.0077 0.0077
Schistosoma mansoni hypothetical protein 0.0158 0.0321 0.0321
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0016 0.001 0.0442
Entamoeba histolytica cysteine surface protein, putative 0.0046 0.0077 0.041
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0046 0.0077 0.1097
Echinococcus multilocularis sex peptide receptor 0.0125 0.0249 0.03
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0017 0.0013 0.0571
Trichomonas vaginalis STE family protein kinase 0.0046 0.0077 0.094
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0046 0.0077 0.0144
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0014 0.0005 0.0221
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.0000011266 0.0000013602
Echinococcus granulosus neuropeptide Y receptor 0.0125 0.0249 0.03
Brugia malayi hypothetical protein 0.0022 0.0024 0.0045
Echinococcus granulosus retinal guanylyl cyclase 2 0.0046 0.0077 0.0093
Brugia malayi SH2 domain containing protein 0.0209 0.043 0.081
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0005 0.0089
Echinococcus multilocularis expressed protein 0.0158 0.032 0.0387
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0006 0.0143
Brugia malayi Tensin 0.0162 0.0329 0.062
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0046 0.0077 0.0093
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0077 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0061 0.0752
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0044 0.0053
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.001 0.0174
Schistosoma mansoni patched 1 0.0042 0.0066 0.0066
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0046 0.0077 0.0093
Schistosoma mansoni smad1 5 8 and 0.0018 0.0015 0.0015
Brugia malayi SRC-1 0.1188 0.2563 0.4825
Loa Loa (eye worm) TK/FER protein kinase 0.0209 0.043 0.052
Giardia lamblia hypothetical protein 0.0039 0.0061 0.0898
Giardia lamblia Protein 21.1 0.0046 0.0077 0.1124
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Echinococcus multilocularis potassium voltage gated channel protein 0.0066 0.0119 0.0144
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0033 0.1454
Schistosoma mansoni neuropeptide receptor 0.1486 0.3213 0.3213
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0046 0.0077 0.0093
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 3 0.0128 0.0254 0.0478
Trichomonas vaginalis heat shock protein, putative 0.0024 0.0028 0.0345
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0209 0.043 0.2307
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0144 1
Loa Loa (eye worm) neuropeptide F receptor 0.0125 0.0249 0.03
Echinococcus granulosus carbonic anhydrase 0.0127 0.0253 0.0306
Loa Loa (eye worm) TK protein kinase 0.0046 0.0077 0.0093
Plasmodium falciparum heat shock protein 90 0.0033 0.0048 0.1262
Brugia malayi hypothetical protein 0.0125 0.0249 0.0468
Onchocerca volvulus 0.0046 0.0077 0.083
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0011 0 0.0003
Echinococcus granulosus retinal guanylyl cyclase 2 0.0046 0.0077 0.0093
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0000011266 0.0000013602
Schistosoma mansoni spingomyelin synthetase-related 0.0128 0.0254 0.0254
Echinococcus multilocularis serotonin receptor 0.0644 0.1379 0.1665
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0062
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.003 0.0041 0.1645
Entamoeba histolytica hypothetical protein, conserved 0.0046 0.0077 0.041
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0229 0.932
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0046 0.0077 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0125 0.0249 0.03
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0125 0.0249 0.03
Schistosoma mansoni tyrosine kinase 0.0209 0.043 0.043
Toxoplasma gondii hypothetical protein 0.0127 0.0253 0.3625
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0047 0.1914
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Echinococcus granulosus smad 0.0018 0.0015 0.0018
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0125 0.0249 0.03
Echinococcus granulosus insulin receptor 0.0094 0.018 0.0217
Brugia malayi hypothetical protein 0.0125 0.0249 0.0468
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0011 0 0.0003
Brugia malayi hypothetical protein 0.006 0.0106 0.0199
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0009 0.0362
Brugia malayi SH2 domain containing protein 0.0209 0.043 0.081
Schistosoma mansoni tyrosine kinase 0.1188 0.2563 0.2563
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0128 0.0254 0.3114
Brugia malayi putative neuropeptide receptor NPR1 0.0125 0.0249 0.0468
Echinococcus granulosus retinal guanylyl cyclase 2 0.0046 0.0077 0.0093
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0039 0.0061 0.0061
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0014 0.0006 0.0007
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0014 0.0006 0.0069
Entamoeba histolytica protein kinase domain containing protein 0.0047 0.0078 0.0418
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.032 0.3927
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0003
Toxoplasma gondii aspartyl protease ASP1 0.0185 0.0378 0.5411
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0005 0.0206
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0158 0.0321 0.0387
Toxoplasma gondii hypothetical protein 0.0128 0.0254 0.3635
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Echinococcus granulosus tyrosine kinase 0.1029 0.2218 0.2678
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0033 0.1747
Loa Loa (eye worm) TK/ALK protein kinase 0.0046 0.0077 0.0093
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0000011266 0.0000013602
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0011 0.0001 0.0003
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0011 0.0000011266 0.0000013602
Brugia malayi SH2 domain containing protein 0.0162 0.0329 0.062
Trypanosoma cruzi polyprenyl synthase, putative 0.0031 0.0044 0.0766
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0158 0.0321 0.0387
Echinococcus multilocularis natriuretic peptide receptor 1 0.0046 0.0077 0.0093
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0039 0.0061 0.0061
Schistosoma mansoni cpg binding protein 0.0024 0.0027 0.0027
Trypanosoma cruzi Heat shock protein 83, putative 0.0033 0.0048 0.0842
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0046 0.0077 0.0093
Giardia lamblia PHD finger protein 15 0.0018 0.0014 0.0209
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.0158 0.032 0.0387
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0077 0.041
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0104 0.0104
Echinococcus multilocularis tar DNA binding protein 0.0173 0.0352 0.0425
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0104 0.1269
Echinococcus granulosus tumor protein p63 0.0665 0.1423 0.1719
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0039 0.0061 0.0115
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0046 0.0077 0.041
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0039 0.0061 0.1077
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Brugia malayi Hsp90 protein 0.0022 0.0024 0.0045
Schistosoma mansoni neuropeptide receptor 0.0125 0.0249 0.0249
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0014 0.0006 0.0069
Onchocerca volvulus 0.0158 0.032 0.3475
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0185 0.0378 0.0378
Toxoplasma gondii PHD-finger domain-containing protein 0.0018 0.0014 0.0206
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0018 0.0016 0.0189
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0125 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.0093
Echinococcus multilocularis heat shock protein 70 0.0046 0.0077 0.0093
Schistosoma mansoni biogenic amine receptor 0.0125 0.0249 0.0249
Trypanosoma brucei importin beta-1 subunit, putative 0.0019 0.0017 0.0287
Onchocerca volvulus 0.0185 0.0378 0.4102
Schistosoma mansoni neuropeptide f receptor 76f 0.0125 0.0249 0.0249
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0077 0.0145
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0031 0.0044 0.1764
Trichomonas vaginalis p67phox protein, putative 0.0158 0.032 0.3927
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0039 0.0061 0.0115
Brugia malayi hypothetical protein 0.0125 0.0249 0.0468
Schistosoma mansoni hypothetical protein 0.0018 0.0014 0.0014
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0014 0.0005 0.0007
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0271 0.0567 0.0684
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0005 0.001
Brugia malayi N-terminal motif family protein 0.0121 0.0239 0.045
Schistosoma mansoni tyrosine kinase 0.0209 0.043 0.043
Schistosoma mansoni protein kinase 0.0046 0.0077 0.0077
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0014 0.0006 0.0096
Echinococcus granulosus dnaJ subfamily B 0.0337 0.0709 0.0856
Brugia malayi neuropeptide F receptor 0.0125 0.0249 0.0468
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0011 0.0000011266 0.0000021211
Brugia malayi hypothetical protein 0.0102 0.0198 0.0372
Brugia malayi RNA recognition motif domain containing protein 0.0173 0.0352 0.0662
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0047 0.1914
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0158 0.032 0.0387
Schistosoma mansoni vav2 0.0162 0.0329 0.0329
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0044 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0061 0.0752
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0003
Onchocerca volvulus 0.0125 0.0249 0.2695
Entamoeba histolytica protein kinase, putative 0.0867 0.1864 1
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0077 0.0077
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.001 0.0121
Echinococcus multilocularis kinase suppressor of Ras 1 0.0046 0.0077 0.0093
Loa Loa (eye worm) hypothetical protein 0.0042 0.0066 0.008
Echinococcus granulosus kinase suppressor of Ras 1 0.0046 0.0077 0.0093
Onchocerca volvulus 0.0162 0.0329 0.3571
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0158 0.0321 0.0387
Brugia malayi hypothetical protein 0.0462 0.0983 0.1851
Onchocerca volvulus 0.0185 0.0378 0.4102
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0125 0.0249 0.0468
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0005 0.0089
Mycobacterium ulcerans polyketide synthase 0.0017 0.0013 0.016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.0249 0.03
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.001 0.0262
Onchocerca volvulus 0.0125 0.0249 0.2695
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0367 0.0775 0.0775
Mycobacterium leprae Probable polyketide synthase Pks1 0.0018 0.0016 0.0674
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.009 0.0108
Schistosoma mansoni hypothetical protein 0.0046 0.0077 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0014 0.0005 0.001
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0125 0.0249 0.03
Loa Loa (eye worm) SRC-1 0.1188 0.2563 0.3094
Echinococcus granulosus NCK adaptor protein 0.0321 0.0674 0.0814
Loa Loa (eye worm) hypothetical protein 0.0128 0.0254 0.0307
Brugia malayi Pepsin A precursor 0.0185 0.0378 0.0712
Brugia malayi Calcitonin receptor-like protein seb-1 0.0501 0.1066 0.2007
Loa Loa (eye worm) Smad1 0.0018 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0185 0.0378 0.0378
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0011 0 0.0003
Schistosoma mansoni cpg binding protein 0.0025 0.003 0.003
Leishmania major cAMP-specific phosphodiesterase, putative 0.0039 0.0061 0.1077
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0014 0.0005 0.0005
Loa Loa (eye worm) TK/Met protein kinase 0.0046 0.0077 0.0093
Echinococcus multilocularis ornithine aminotransferase 0.0016 0.001 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0158 0.032 0.5651
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0158 0.0321 0.0321
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0046 0.0077 0.0077
Plasmodium vivax heat shock protein 90, putative 0.0022 0.0024 0.0619
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0144 0.0173
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0066 0.008
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0162 0.0329 0.062
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0077 0.094
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0031 0.0044 0.177
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0014 0.0005 0.001
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Loa Loa (eye worm) MH2 domain-containing protein 0.0267 0.0558 0.0674
Echinococcus multilocularis tyrosine protein kinase 0.0046 0.0077 0.0093
Plasmodium vivax tyrosine kinase-like protein, putative 0.0046 0.0077 0.2023
Onchocerca volvulus 0.0046 0.0077 0.083
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0185 0.0378 0.0457
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0046 0.0077 0.0093
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0077 0.1353
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0066 0.0119 0.0144
Schistosoma mansoni protein kinase 0.0046 0.0077 0.0077
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0075 0.0091
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0062
Echinococcus multilocularis tyrosine protein kinase shark 0.0209 0.043 0.052
Echinococcus multilocularis 0.0162 0.0329 0.0397
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0017 0.0013 0.0571
Echinococcus multilocularis geminin 0.1036 0.2232 0.2695
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0162 0.0329 0.0329
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0009 0.0362
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0059 0.0104 0.1832
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Echinococcus multilocularis 0.0047 0.0077 0.0093
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0203 0.8283
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0077 0.041
Loa Loa (eye worm) TK/FER protein kinase 0.0209 0.043 0.052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.0249 0.0249
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0039 0.0061 0.1077
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0015 0.0018
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0044 0.0053
Loa Loa (eye worm) p53BP2 0.0158 0.032 0.0387
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0031 0.0044 0.3015
Echinococcus granulosus tyrosine protein kinase pr2 0.0046 0.0077 0.0093
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Schistosoma mansoni mixed-lineage leukemia protein mll 0.005 0.0085 0.0085
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0031 0.0044 0.1148
Schistosoma mansoni amine GPCR 0.0125 0.0249 0.0249
Brugia malayi aspartic protease BmAsp-1, identical 0.0185 0.0378 0.0712
Echinococcus granulosus g protein coupled receptor 0.0125 0.0249 0.03
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.001 0.0262
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Schistosoma mansoni slit-robo rho gtpase activating protein 0.0158 0.032 0.032
Echinococcus granulosus tyrosine protein kinase csk 0.0046 0.0077 0.0093
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1188 0.2563 0.3094
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Echinococcus granulosus tm gpcr rhodopsin 0.1042 0.2245 0.2711
Brugia malayi CXXC zinc finger family protein 0.0024 0.0027 0.0051
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Loa Loa (eye worm) endoplasmin 0.0033 0.0048 0.0058
Giardia lamblia Kinase 0.0046 0.0077 0.1124
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0046 0.0077 0.0144
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0018 0.0016 0.0674
Loa Loa (eye worm) hypothetical protein 0.0158 0.032 0.0387
Echinococcus multilocularis SH2 motif 0.0162 0.0329 0.0397
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0077 0.094
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0039 0.0061 0.0752
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0077 0.041
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0103 0.0124
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.1029 0.2218 0.2678
Schistosoma mansoni hypothetical protein 0.0162 0.0329 0.0329
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0059 0.0104 0.4236
Schistosoma mansoni formin binding protein and related proteins 0.0158 0.032 0.032
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0009 0.0109
Echinococcus multilocularis c src tyrosine kinase 0.0367 0.0775 0.0936
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0062
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1081 0.233 0.2813
Plasmodium vivax plasmepsin IV, putative 0.0185 0.0378 1
Echinococcus granulosus somatostatin receptor 0.0125 0.0249 0.03
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0022 0.0024 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0119 0.1464
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Loa Loa (eye worm) polyprenyl synthetase 0.0124 0.0245 0.0296
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0203 0.8283
Echinococcus multilocularis neuropeptide receptor 0.1486 0.3213 0.3879
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0044 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0119 0.1464
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0031 0.0044 0.2508
Echinococcus granulosus hematopoietic lineage cell specific protein 0.0158 0.032 0.0387
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Loa Loa (eye worm) G-protein coupled receptor 0.0125 0.0249 0.03
Echinococcus multilocularis survival motor neuron protein 1 0.0462 0.0983 0.1187
Onchocerca volvulus 0.0209 0.043 0.4669
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.019 0.019
Brugia malayi integrin-linked kinase 0.0046 0.0077 0.0144
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0011 0 0.0003
Brugia malayi Steroid receptor seven-up type 2 0.0014 0.0005 0.001
Echinococcus multilocularis PHD finger protein rhinoceros 0.0018 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0005 0.001
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0046 0.0077 0.0077
Schistosoma mansoni glutathione synthetase 0.0031 0.0044 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0014 0.0005 0.001
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Entamoeba histolytica serine/threonine protein kinase, putative 0.0066 0.0119 0.0639
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0125 0.0249 0.03
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Brugia malayi Bromodomain containing protein 0.0018 0.0014 0.0027
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0144 0.0173
Schistosoma mansoni tar DNA-binding protein 0.0173 0.0352 0.0352
Echinococcus granulosus fch and double sh3 domains protein 2 0.0158 0.032 0.0387
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Onchocerca volvulus 0.0094 0.0181 0.1963
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Trypanosoma cruzi protein kinase, putative 0.0046 0.0077 0.1349
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0051 0.1351
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0077 0.041
Entamoeba histolytica SH2 domain containing protein 0.0162 0.0329 0.1765
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0047 0.0078 0.1375
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0115 0.1401
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0125 0.0249 0.2695
Schistosoma mansoni tensin 0.0162 0.0329 0.0329
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0044 0.0533
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0000011266 0.0000013602
Brugia malayi nuclear hormone receptor 0.0014 0.0005 0.001
Echinococcus multilocularis tyrosine protein kinase ABL1 0.3813 0.8283 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0125 0.0249 0.03
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.001 0.0262
Echinococcus granulosus c src tyrosine kinase 0.0367 0.0775 0.0936
Trypanosoma brucei heat shock protein, putative 0.0033 0.0048 0.0842
Echinococcus granulosus epidermal growth factor receptor kinase 0.0158 0.032 0.0387
Echinococcus multilocularis neuropeptides capa receptor 0.0125 0.0249 0.03
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0185 0.0378 0.5411
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0077 0.041
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.0249 0.0249
Plasmodium vivax protein kinase, putative 0.0046 0.0077 0.2023
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0124 0.0245 0.4326
Onchocerca volvulus 0.0158 0.032 0.3475
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0039 0.0061 0.0074
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0046 0.0077 0.0093
Treponema pallidum octaprenyl-diphosphate synthase 0.0031 0.0044 0.2508
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0047 0.0078 0.1375
Brugia malayi SH2 domain containing protein 0.0162 0.0329 0.062
Schistosoma mansoni cathepsin D (A01 family) 0.0185 0.0378 0.0378
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.001 0.0174
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0077 0.0093
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0128 0.0254 0.3114
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0031 0.0044 0.3025
Leishmania major carbonic anhydrase-like protein 0.0271 0.0567 1
Echinococcus granulosus fmrfamide receptor 0.0125 0.0249 0.03
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Loa Loa (eye worm) PDE1B protein 0.0039 0.0061 0.0074
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0203 0.8283
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0112 0.022 0.9633
Schistosoma mansoni thyroid hormone receptor 0.0014 0.0005 0.0005
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0039 0.0061 0.1077
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0119 0.0119
Loa Loa (eye worm) TK/INSR protein kinase 0.0094 0.018 0.0217
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0017 0.0013 0.0532
Schistosoma mansoni ephrin receptor 0.0046 0.0077 0.0077
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0124 0.0245 0.4326
Echinococcus multilocularis G protein coupled receptor 139 0.1486 0.3213 0.3879
Schistosoma mansoni tyrosine kinase 0.3651 0.7929 0.7929
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0012 0.0001 0.0038
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.001 0.0121
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.0093
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Schistosoma mansoni Dab2-interacting protein-like 0.0158 0.032 0.032
Plasmodium falciparum thioredoxin reductase 0.0016 0.001 0.0262
Schistosoma mansoni hypothetical protein 0.0125 0.0249 0.0249
Echinococcus granulosus alpha 1A adrenergic receptor 0.0125 0.0249 0.03
Trypanosoma cruzi hypothetical protein, conserved 0.0158 0.032 0.5651
Echinococcus multilocularis tyrosine protein kinase HCK 0.0867 0.1864 0.2251
Toxoplasma gondii PHD-finger domain-containing protein 0.0018 0.0014 0.0206
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0039 0.0061 0.0061
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0009 0.0362
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0046 0.0077 0.0093
Loa Loa (eye worm) thyroid receptor interactor 0.0158 0.032 0.0387
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0323 0.068 0.0821
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0048 0.0256
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0031 0.0044 0.177
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Trypanosoma brucei Pseudokinase, putative 0.0046 0.0077 0.1349
Trypanosoma cruzi polo-like protein kinase, putative 0.0066 0.0119 0.2104
Echinococcus granulosus carbonic anhydrase 0.0127 0.0253 0.0306
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0104 0.1269
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Schistosoma mansoni dreadlocks/dock 0.0158 0.032 0.032
Schistosoma mansoni thyroid hormone receptor 0.0014 0.0005 0.0005
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0125 0.0249 0.0249
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0046 0.0077 0.0093
Echinococcus multilocularis tyrosine protein kinase csk 0.0046 0.0077 0.0093
Loa Loa (eye worm) hypothetical protein 0.2449 0.5311 0.6413
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0006
Schistosoma mansoni tyrosine protein kinase 0.0046 0.0077 0.0077
Trichomonas vaginalis TK family protein kinase 0.0046 0.0077 0.094
Loa Loa (eye worm) hypothetical protein 0.0185 0.0378 0.0457
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0162 0.0329 0.3571
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0016 0.001 0.0442
Schistosoma mansoni tyrosine kinase 0.0126 0.0251 0.0251
Plasmodium falciparum plasmepsin VII 0.0185 0.0378 1
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0031 0.0044 0.0233
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0271 0.0567 0.0567
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0035 0.0051 0.0062
Schistosoma mansoni signal transduction protein lnk-related 0.0162 0.0329 0.0329
Brugia malayi GnHR receptor homolog 0.0125 0.0249 0.0468
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0000011266 0.0000011266
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0014 0.0005 0.0007
Echinococcus granulosus neuropeptide receptor A26 0.0504 0.1074 0.1296
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0061 0.1077
Brugia malayi Serotonin receptor 0.0125 0.0249 0.0468
Schistosoma mansoni heat shock protein 0.0022 0.0024 0.0024
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0012 0.0001 0.0001
Echinococcus granulosus tyrosine protein kinase csk 0.0046 0.0077 0.0093
Echinococcus multilocularis tyrosine protein kinase Srms 0.1029 0.2218 0.2678
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0014 0.0005 0.0007
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0000011266 0.0000011266
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0077 0.0093
Echinococcus multilocularis GPCR, family 2 0.0158 0.0321 0.0387
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0127 0.0253 0.0477
Echinococcus granulosus tyrosine kinase 0.0046 0.0077 0.0093
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0044 0.0774
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0015 0.0009 0.0109
Schistosoma mansoni opsin-like receptor 0.0125 0.0249 0.0249
Mycobacterium ulcerans polyketide synthase Pks9 0.0011 0.0001 0.0003
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.0028 0.0037 0.1591
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0125 0.0249 0.0249
Brugia malayi Serine/threonine-protein kinase Pim-3 0.016 0.0325 0.0611
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0125 0.0249 0.0249
Echinococcus granulosus expressed conserved protein 0.0091 0.0174 0.0211
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0124 0.0245 0.0245
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0059 0.0104 0.1832
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0278 0.0336
Giardia lamblia Kinase, NEK 0.0046 0.0077 0.1124
Trichomonas vaginalis conserved hypothetical protein 0.0128 0.0254 0.3114
Schistosoma mansoni hypothetical protein 0.0125 0.0249 0.0249
Giardia lamblia Kinase, PLK 0.0066 0.0119 0.1753
Loa Loa (eye worm) CAMK/PIM protein kinase 0.016 0.0325 0.0392
Echinococcus granulosus protein kinase 0.0046 0.0077 0.0093
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0028 0.0037 0.0445
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0203 0.8888
Brugia malayi tRNA modification GTPase TrmE family protein 0.0162 0.0329 0.062
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0016 0.001 0.0442
Echinococcus granulosus tyrosine protein kinase shark 0.0209 0.043 0.052
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Echinococcus granulosus carbonic anhydrase II 0.0271 0.0567 0.0684
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0125 0.0249 0.0249
Loa Loa (eye worm) TAR-binding protein 0.0173 0.0352 0.0425
Echinococcus granulosus G protein coupled receptor 139 0.0125 0.0249 0.03
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0018 0.0016 0.0674
Schistosoma mansoni carbonic anhydrase-related 0.0127 0.0253 0.0253
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Schistosoma mansoni neuropeptide F-like receptor 0.0125 0.0249 0.0249
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0104 0.1484
Entamoeba histolytica protein kinase, putative 0.0158 0.032 0.1718
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0077 0.094
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0046 0.0077 0.0144
Loa Loa (eye worm) CXXC zinc finger family protein 0.0024 0.0027 0.0033
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0033 0.0047 0.0089
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0158 0.032 0.0387
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0061 0.1077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0125 0.0249 0.03
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0128 0.0254 0.6716
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Loa Loa (eye worm) polyprenyl synthetase 0.0031 0.0044 0.0053
Onchocerca volvulus 0.0097 0.0188 0.2032
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0031 0.0044 0.0766
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0185 0.0378 0.4635
Loa Loa (eye worm) TK/FER protein kinase 0.0209 0.043 0.052
Echinococcus granulosus heat shock protein 90 0.0028 0.0038 0.0045
Schistosoma mansoni tyrosine kinase 0.0126 0.0251 0.0251
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0077 0.041
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Trypanosoma cruzi heat shock protein 85, putative 0.0028 0.0038 0.0657
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0077 0.094
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0014 0.0006 0.0144
Mycobacterium ulcerans heat shock protein 90 0.0031 0.0044 0.053
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0162 0.0329 0.0397
Loa Loa (eye worm) hypothetical protein 0.0127 0.0253 0.0306
Trichomonas vaginalis importin beta-1, putative 0.0015 0.0009 0.0108
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0173 0.0352 0.0425
Schistosoma mansoni growth factor receptor-bound protein 0.0321 0.0674 0.0674
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0125 0.0249 0.03
Entamoeba histolytica hypothetical protein 0.0046 0.0077 0.041
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0005 0.0007
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.001 0.0145
Echinococcus granulosus g protein coupled receptor 0.0125 0.0249 0.03
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0014 0.0005 0.0076
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0046 0.0077 0.083
Echinococcus multilocularis raf serine:threonine protein kinase 0.0046 0.0077 0.0093
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0046 0.0077 0.0093
Echinococcus granulosus dro:myosuppressin receptor 0.0125 0.0249 0.03
Leishmania major trypanothione reductase 0.0046 0.0075 0.1326
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0077 0.094
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0077 0.0093
Echinococcus granulosus fibroblast growth factor receptor 4 0.0046 0.0077 0.0093
Plasmodium falciparum sphingomyelin synthase 2, putative 0.0128 0.0254 0.6716
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0081 0.0432
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0031 0.0044 0.0532
Trypanosoma cruzi PAB1-binding protein , putative 0.0035 0.0051 0.0891
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0061 0.1077
Echinococcus multilocularis dnaJ subfamily B 0.0337 0.0709 0.0856
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Echinococcus granulosus tyrosine protein kinase Blk 0.1029 0.2218 0.2678
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Loa Loa (eye worm) STAT protein 0.0162 0.0329 0.0397
Brugia malayi Furin-like cysteine rich region family protein 0.0196 0.0403 0.0758
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.001 0.0403
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0000011266 0.0000011266
Loa Loa (eye worm) TK/ABL protein kinase 0.3813 0.8283 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Echinococcus granulosus tyrosine protein kinase csk 0.0046 0.0077 0.0093
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0059 0.0104 0.724
Echinococcus multilocularis jumonji domain containing protein 0.0025 0.003 0.0036
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0321 0.0674 0.0814
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.032 0.3927
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0005 0.0065
Brugia malayi CHE-14 protein 0.0042 0.0066 0.0125
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0162 0.0329 0.0397
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0066 0.008
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0077 0.041
Echinococcus multilocularis intersectin 2 0.0158 0.032 0.0387
Leishmania major farnesyl pyrophosphate synthase 0.0124 0.0245 0.4326
Loa Loa (eye worm) TK/RYK protein kinase 0.0046 0.0077 0.0093
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0323 0.068 0.068
Echinococcus granulosus ephrin type A receptor 4 A 0.0046 0.0077 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Loa Loa (eye worm) fatty acid synthase 0.0017 0.0013 0.0015
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0077 0.041
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1188 0.2563 0.3094
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0284 0.0594 0.0718
Toxoplasma gondii STE kinase 0.0046 0.0077 0.1097
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0104 0.0125
Loa Loa (eye worm) protein-tyrosine kinase 0.0158 0.032 0.0387
Brugia malayi hypothetical protein 0.0011 0 0.0001
Brugia malayi Receptor family ligand binding region containing protein 0.0046 0.0077 0.0144
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0125 0.0249 0.03
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0046 0.0077 0.0077
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.001 0.0012
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Leishmania major protein kinase, putative 0.0047 0.0078 0.1375
Echinococcus granulosus biogenic amine 5HT receptor 0.0644 0.1379 0.1665
Plasmodium falciparum phosphodiesterase delta, putative 0.0039 0.0061 0.1615
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0039 0.0061 0.0115
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0077 0.3128
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0011 0 0.0003
Trichomonas vaginalis endoplasmin, putative 0.0024 0.0028 0.0345
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.001 0.0019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1042 0.2245 0.2711
Echinococcus multilocularis tyrosine protein kinase csk 0.0046 0.0077 0.0093
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0000011266 0.0000013602
Brugia malayi hypothetical protein 0.0209 0.043 0.081
Entamoeba histolytica tyrosin kinase, putative 0.0046 0.0077 0.041
Onchocerca volvulus 0.0162 0.0329 0.3571
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0119 0.0236 0.0285
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0014 0.0005 0.0062
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0185 0.0378 0.0378
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Onchocerca volvulus Bile acid receptor homolog 0.0014 0.0005 0.0056
Entamoeba histolytica hypothetical protein, conserved 0.0158 0.032 0.1718
Brugia malayi Sex muscle abnormal protein 5 0.0321 0.0674 0.1269
Echinococcus granulosus tyrosine protein kinase Srms 0.0209 0.043 0.052
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0001 0.0002
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0016 0.001 0.0412
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0077 0.041
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0162 0.0329 0.0329
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Schistosoma mansoni tyrosine kinase 0.0094 0.018 0.018
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0031 0.0044 0.3025
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0011 0.0000011266 0.0000021211
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0229 1
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Loa Loa (eye worm) TK protein kinase 0.0046 0.0077 0.0093
Echinococcus multilocularis protein dispatched 1 0.0048 0.0079 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Onchocerca volvulus 0.0125 0.0249 0.2695
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0039 0.0061 0.0115
Trypanosoma cruzi heat shock protein 90, putative 0.0014 0.0006 0.0099
Brugia malayi MH1 domain containing protein 0.0018 0.0015 0.0029
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0059 0.0104 0.0104
Loa Loa (eye worm) heat shock protein 75 0.0022 0.0024 0.0029
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0983 0.2117 0.2556
Brugia malayi hypothetical protein 0.0434 0.0921 0.1735
Plasmodium vivax aspartyl protease, putative 0.0185 0.0378 1
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0059 0.0104 0.1832
Brugia malayi Probable ClpP-like protease 0.0077 0.0144 0.0271
Brugia malayi G protein-coupled receptor 0.0125 0.0249 0.0468
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0007
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0031 0.0044 0.0766
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0185 0.0378 0.0378
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0367 0.0775 0.0936
Brugia malayi Tyrosine-protein kinase PR2 0.0046 0.0077 0.0144
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0014 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Brugia malayi dehydrogenases, short chain protein 2 0.0011 0 0.0001
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0011 0.0000011266 0.0000013602
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0039 0.0061 0.0074
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0011 0 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.0249 0.03
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.001 0.0125
Loa Loa (eye worm) TK/FER protein kinase 0.0209 0.043 0.052
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0046 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0144 1
Entamoeba histolytica ankyrin repeat protein 0.0046 0.0077 0.041
Brugia malayi MH2 domain containing protein 0.0018 0.0015 0.0029
Schistosoma mansoni adapter molecule crk 0.0321 0.0674 0.0674
Brugia malayi Protein kinase domain containing protein 0.0209 0.043 0.081
Echinococcus multilocularis epidermal growth factor receptor 0.0196 0.0403 0.0486
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0011 0 0.0003
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0162 0.0329 0.0329
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0001 0.0002
Schistosoma mansoni tensin 0.0162 0.0329 0.0329
Echinococcus multilocularis receptor type guanylyl cyclase 0.0046 0.0077 0.0093
Loa Loa (eye worm) glutaminase 2 0.0386 0.0816 0.0985
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0125 0.0249 0.03
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0044 0.0774
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0000011266 0.0000011266
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.0158 0.032 0.032
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0064 0.0115 0.4662
Echinococcus multilocularis epidermal growth factor receptor kinase 0.0158 0.032 0.0387
Loa Loa (eye worm) hypothetical protein 0.0035 0.0051 0.0062
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0124 0.0245 0.3005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.0249 0.0249
Loa Loa (eye worm) aspartyl protease 6 0.0185 0.0378 0.0457
Loa Loa (eye worm) glutathione reductase 0.0046 0.0075 0.0091
Brugia malayi hypothetical protein 0.0125 0.0249 0.0468
Loa Loa (eye worm) guanylate kinase 0.0158 0.032 0.0387
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0046 0.0077 0.0093
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0003
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.0128 0.0254 0.0478
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.0005 0.0005
Onchocerca volvulus 0.0125 0.0249 0.2695
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0077 0.041
Schistosoma mansoni carbonic anhydrase-related 0.0127 0.0253 0.0253
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0144 0.2055
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0014 0.0005 0.001
Entamoeba histolytica hypothetical protein 0.0015 0.0009 0.0046
Echinococcus multilocularis FTZ F1 alpha 0.0014 0.0005 0.0007
Echinococcus granulosus peptide allatostatin:somatostatin 0.0125 0.0249 0.03
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0046 0.0077 0.0144
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0066 0.008
Loa Loa (eye worm) hypothetical protein 0.0077 0.0144 0.0173
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.01 0.0193 0.2362
Loa Loa (eye worm) hypothetical protein 0.1425 0.3079 0.3718
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0125 0.0249 0.03
Schistosoma mansoni heat shock protein 0.0033 0.0048 0.0048
Entamoeba histolytica serine/threonine kinase, putative 0.0046 0.0077 0.041
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0017 0.0013 0.0532
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.0093
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0011 0 0.0003
Schistosoma mansoni tyrosine kinase 0.008 0.015 0.015
Loa Loa (eye worm) TK protein kinase 0.0867 0.1864 0.2251
Schistosoma mansoni growth hormone secretagogue receptor 0.0125 0.0249 0.0249
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0125 0.0249 0.0468
Onchocerca volvulus 0.0125 0.0249 0.2695
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0162 0.0329 0.0397
Entamoeba histolytica Ran family GTPase 0.0014 0.0006 0.0029
Schistosoma mansoni hypothetical protein 0.0337 0.0709 0.0709
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.0158 0.032 0.0387
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0014 0.0005 0.0027
Loa Loa (eye worm) neuropeptide F receptor 0.0125 0.0249 0.03
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0046 0.0077 0.094
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0000011266 0.0000011266
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Loa Loa (eye worm) TK protein kinase 0.0046 0.0077 0.0093
Loa Loa (eye worm) hypothetical protein 0.0158 0.0321 0.0387
Echinococcus multilocularis cpg binding protein 0.0025 0.003 0.0036
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0077 0.0411
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0284 0.0594 0.0718
Brugia malayi hypothetical protein 0.0035 0.0051 0.0096
Plasmodium falciparum ataxin-2 like protein, putative 0.0035 0.0051 0.1336
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.016 0.0325 0.3521
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0017 0.0012 0.0485
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.0093
Schistosoma mansoni neuropeptide receptor 0.0125 0.0249 0.0249
Entamoeba histolytica hypothetical protein 0.0046 0.0077 0.041
Schistosoma mansoni cell polarity protein 0.0158 0.032 0.032
Loa Loa (eye worm) SH2 domain-containing protein 0.0162 0.0329 0.0397
Onchocerca volvulus Protein ultraspiracle homolog 0.0014 0.0005 0.0056
Echinococcus granulosus N chimaerin 0.0162 0.0329 0.0397
Trichomonas vaginalis protein tyrosine kinase, putative 0.0046 0.0077 0.094
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Loa Loa (eye worm) hypothetical protein 0.0158 0.032 0.0387
Loa Loa (eye worm) hypothetical protein 0.0158 0.032 0.0387
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Echinococcus multilocularis neuropeptide s receptor 0.0504 0.1074 0.1296
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0014 0.0005 0.0007
Entamoeba histolytica hypothetical protein 0.0046 0.0077 0.041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0047 0.1914
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0125 0.0249 0.03
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0112 0.022 0.8978
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0158 0.032 0.032
Echinococcus granulosus PHD finger protein rhinoceros 0.0018 0.0014 0.0017
Trypanosoma brucei heat shock protein, putative 0.0033 0.0048 0.0842
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0075 0.3065
Echinococcus multilocularis fmrfamide receptor 0.0125 0.0249 0.03
Echinococcus granulosus SHC transforming protein 3 0.0162 0.0329 0.0397
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0044 0.0053
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0162 0.0329 0.0397
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0062
Mycobacterium ulcerans thioesterase 0.0014 0.0007 0.0083
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0077 0.041
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0125 0.0249 0.0249
Plasmodium falciparum tyrosine kinase-like protein 0.0046 0.0077 0.2023
Schistosoma mansoni kinase 0.0034 0.0049 0.0049
Echinococcus granulosus Spectrin alpha actinin 0.0158 0.032 0.0387
Echinococcus multilocularis N chimaerin 0.0162 0.0329 0.0397
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0271 0.0567 0.1067
Loa Loa (eye worm) hypothetical protein 0.0158 0.032 0.0387
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0014 0.0005 0.0221
Echinococcus granulosus potassium voltage gated channel protein 0.0066 0.0119 0.0144
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0086 0.3742
Brugia malayi Immunoglobulin I-set domain containing protein 0.0046 0.0077 0.0144
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0162 0.0329 0.0397
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0151 0.0304 0.0304
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0014 0.0005 0.0007
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.1615
Schistosoma mansoni protein kinase 0.0046 0.0077 0.0077
Brugia malayi hypothetical protein 0.0125 0.0249 0.0468
Echinococcus multilocularis protein patched 0.0042 0.0066 0.008
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0162 0.0329 0.0397
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0077 0.0145
Trypanosoma cruzi GMP reductase 0.0059 0.0104 0.1832
Toxoplasma gondii protein kinase 0.0046 0.0077 0.1097
Entamoeba histolytica BAR/SH3 domain containing protein 0.0158 0.032 0.1718
Loa Loa (eye worm) TK/FER protein kinase 0.0209 0.043 0.052
Echinococcus granulosus serotonin receptor 0.0125 0.0249 0.03
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0077 0.094
Brugia malayi Protein kinase domain containing protein 0.0209 0.043 0.081
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0187 0.0226
Entamoeba histolytica protein kinase, putative 0.0163 0.0331 0.1773
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0077 0.0093
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Loa Loa (eye worm) hypothetical protein 0.0128 0.0254 0.0307
Mycobacterium tuberculosis Probable reductase 0.0105 0.0203 0.8283
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0031 0.0044 0.0082
Brugia malayi hypothetical protein 0.0125 0.0249 0.0468
Plasmodium falciparum importin beta, putative 0.0019 0.0017 0.043
Echinococcus granulosus survival motor neuron protein 1 0.0462 0.0983 0.1187
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0009 0.0017
Schistosoma mansoni Smad4 0.0018 0.0015 0.0015
Trypanosoma brucei heat shock protein, putative 0.0033 0.0048 0.0842
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0044 0.0774
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus granulosus 7TM GPCR rhodopsin 0.0125 0.0249 0.03
Brugia malayi Variant SH3 domain containing protein 0.0162 0.0329 0.062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0125 0.0249 0.0249
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Plasmodium vivax acetyl-CoA synthetase, putative 0.0014 0.0005 0.0134
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0044 0.0631
Loa Loa (eye worm) G-protein coupled receptor 0.0125 0.0249 0.03
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0144 0.2055
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Brugia malayi steroid hormone receptor 0.0014 0.0005 0.001
Mycobacterium ulcerans hypothetical protein 0.0047 0.0077 0.094
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0077 0.094
Onchocerca volvulus 0.0027 0.0034 0.0364
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.0249 0.03
Echinococcus multilocularis tensin 0.0162 0.0329 0.0397
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.01 0.0193 0.7863
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0125 0.0249 0.03
Echinococcus granulosus tyrosine protein kinase Lyn 0.1188 0.2564 0.3096
Brugia malayi GMP reductase 0.0025 0.0029 0.0055
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0039 0.0061 0.0074
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0016 0.001 0.0412
Brugia malayi STAT protein, DNA binding domain containing protein 0.0162 0.0329 0.062
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0124 0.0245 0.0296
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Plasmodium vivax aspartyl proteinase, putative 0.0185 0.0378 1
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.0158 0.032 0.0387
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0014 0.0005 0.0056
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0031 0.0044 0.0624
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0005 0.0089
Giardia lamblia Heat shock protein HSP 90-alpha 0.0028 0.0038 0.0548
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0086 0.0104
Loa Loa (eye worm) hypothetical protein 0.0102 0.0198 0.0239
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0158 0.0321 0.0387
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0000011266 0.0000011266
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0127 0.0253 0.0477
Schistosoma mansoni smad1 5 8 and 0.0018 0.0015 0.0015
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0128 0.0254 0.6716
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0014 0.0005 0.0007
Onchocerca volvulus 0.0125 0.0249 0.2695
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0163 0.0331 0.1773
Onchocerca volvulus Alhambra homolog 0.0018 0.0014 0.0154
Toxoplasma gondii oxidoreductase, putative 0.0011 0 0.0003
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0323 0.068 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0051 0.0626
Leishmania major importin beta-1 subunit, putative 0.0015 0.0009 0.015
Brugia malayi hypothetical protein 0.0046 0.0077 0.0144
Brugia malayi hypothetical protein 0.0011 0 0.0001
Brugia malayi MH2 domain containing protein 0.0267 0.0558 0.1051
Loa Loa (eye worm) hypothetical protein 0.0047 0.0077 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0077 0.094
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0006
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0119 0.0236 0.0285
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Entamoeba histolytica hypothetical protein 0.0128 0.0254 0.1361
Entamoeba histolytica hypothetical protein 0.0158 0.032 0.1718
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0009 0.0362
Brugia malayi glutathione reductase 0.0046 0.0075 0.0142
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Echinococcus granulosus neuropeptides capa receptor 0.0125 0.0249 0.03
Echinococcus granulosus Smad4 0.0018 0.0015 0.0018
Brugia malayi SH2 domain containing protein 0.0162 0.0329 0.062
Loa Loa (eye worm) TK/ACK protein kinase 0.0046 0.0077 0.0093
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Trypanosoma cruzi PAB1-binding protein , putative 0.0035 0.0051 0.0891
Plasmodium falciparum heat shock protein 90, putative 0.0126 0.025 0.6606
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Loa Loa (eye worm) IMP dehydrogenase 1 0.0059 0.0104 0.0126
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0026 0.0032 0.1294
Loa Loa (eye worm) TK/FER protein kinase 0.0209 0.043 0.052
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0046 0.0077 0.0093
Schistosoma mansoni retinoic acid receptor RXR 0.0014 0.0005 0.0005
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0005 0.0206
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0046 0.0077 0.0093
Brugia malayi Fes/CIP4 homology domain containing protein 0.0158 0.032 0.0603
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Schistosoma mansoni shc transforming protein 0.0162 0.0329 0.0329
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0025 0.0029 0.0055
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Giardia lamblia Hypothetical protein 0.0039 0.0061 0.0898
Entamoeba histolytica hypothetical protein 0.0158 0.032 0.1718
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0066 0.0119 0.2104
Plasmodium vivax glutathione reductase, putative 0.0046 0.0075 0.1988
Plasmodium falciparum plasmepsin V 0.0185 0.0378 1
Loa Loa (eye worm) steroid hormone receptor 0.0014 0.0005 0.0007
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0104 0.1826
Brugia malayi hypothetical protein 0.0125 0.0249 0.0468
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0016 0.001 0.0124
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0014 0.0005 0.001
Schistosoma mansoni carbonic anhydrase 0.0127 0.0253 0.0253
Onchocerca volvulus Serine\/threonine kinase homolog 0.0066 0.0119 0.1294
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0015 0.0018
Plasmodium falciparum plasmepsin I 0.0185 0.0378 1
Schistosoma mansoni tensin-related 0.0162 0.0329 0.0329
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0047 0.0078 0.0094
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0014 0.0005 0.0007
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0104 0.0125
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0046 0.0077 0.0093
Brugia malayi Polyprenyl synthetase family protein 0.0031 0.0044 0.0082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.0249 0.03
Plasmodium falciparum plasmepsin VIII, putative 0.0185 0.0378 1
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Loa Loa (eye worm) hypothetical protein 0.0035 0.0051 0.0062
Plasmodium falciparum phosphodiesterase gamma, putative 0.0039 0.0061 0.1615
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0039 0.0061 0.0061
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0201 0.0413 0.0498
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Plasmodium falciparum plasmepsin IV 0.0185 0.0378 1
Brugia malayi Src substrate cortactin 0.0158 0.032 0.0603
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0039 0.0061 0.0061
Echinococcus granulosus SH2 motif 0.0162 0.0329 0.0397
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0044 0.1161
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0151 0.0304 0.0368
Schistosoma mansoni cellular tumor antigen P53 0.0097 0.0188 0.0188
Giardia lamblia Farnesyl diphosphate synthase 0.0124 0.0245 0.3605
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0007
Echinococcus multilocularis transfer RNA-Thr 0.0046 0.0077 0.0093
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0046 0.0077 0.0144
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.001 0.0174
Trichomonas vaginalis neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative 0.0158 0.032 0.3927
Echinococcus granulosus activated cdc42 kinase 1 0.0046 0.0077 0.0093
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0014 0.0005 0.001
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0011 0 0.0003
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Loa Loa (eye worm) TK/DDR protein kinase 0.0046 0.0077 0.0093
Plasmodium falciparum ornithine aminotransferase 0.0016 0.001 0.0267
Echinococcus multilocularis sphingomyelin synthase protein 1 0.0128 0.0254 0.0307
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0014 0.0005 0.0005
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.016 0.0325 0.0392
Echinococcus multilocularis heat shock protein 90 0.0033 0.0048 0.0058
Schistosoma mansoni trans-prenyltransferase 0.0031 0.0044 0.0044
Onchocerca volvulus 0.0209 0.043 0.4669
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0031 0.0044 0.0053
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0016 0.001 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0014 0.0005 0.0007
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0077 0.041
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0039 0.0061 0.1077
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0003
Loa Loa (eye worm) SH2 domain-containing protein 0.0162 0.0329 0.0397
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0048 0.008 0.1145
Echinococcus multilocularis Spectrin alpha actinin 0.0158 0.032 0.0387
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0061 0.1077
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0185 0.0378 0.0378
Schistosoma mansoni tyrosine kinase 0.0094 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0185 0.0378 0.0457
Loa Loa (eye worm) TK protein kinase 0.0046 0.0077 0.0093
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0031 0.0044 0.0766
Echinococcus multilocularis allatostatin A receptor 0.0125 0.0249 0.03
Onchocerca volvulus 0.0046 0.0077 0.083
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Echinococcus granulosus expressed conserved protein 0.0162 0.0329 0.0397
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.01 0.0193 0.2362
Entamoeba histolytica receptor protein kinase, putative 0.0046 0.0077 0.041
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Loa Loa (eye worm) hypothetical protein 0.0127 0.0253 0.0306
Loa Loa (eye worm) hypothetical protein 0.0644 0.1379 0.1665
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1188 0.2563 0.3094
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Schistosoma mansoni hypothetical protein 0.0158 0.032 0.032
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0039 0.0061 0.0752
Plasmodium falciparum tyrosine kinase-like protein 0.0046 0.0077 0.2023
Schistosoma mansoni ran 0.0014 0.0006 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.0249 0.03
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0005 0.0007
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0039 0.0061 0.0115
Echinococcus multilocularis rhodopsin orphan GPCR 0.0125 0.0249 0.03
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0125 0.0249 0.0249
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0174
Trypanosoma brucei heat shock protein, putative 0.0033 0.0048 0.0842
Onchocerca volvulus 0.0209 0.043 0.4669
Schistosoma mansoni hypothetical protein 0.0094 0.0181 0.0181
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0174
Onchocerca volvulus 0.0044 0.0071 0.0768
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0278 0.0336
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Trypanosoma cruzi paraflagellar rod protein 5, putative 0.0158 0.032 0.5651
Plasmodium vivax endoplasmin, putative 0.0033 0.0048 0.1262
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0039 0.0061 0.0074
Schistosoma mansoni biogenic amine receptor 0.0125 0.0249 0.0249
Plasmodium vivax heat shock protein, putative 0.0126 0.025 0.6606
Echinococcus granulosus sex peptide receptor 0.0125 0.0249 0.03
Entamoeba histolytica hypothetical protein 0.0046 0.0077 0.041
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0044 0.0533
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0015 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0125 0.0249 0.03
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0014 0.0006 0.008
Toxoplasma gondii hypothetical protein 0.0027 0.0033 0.0478
Echinococcus multilocularis SH2 motif 0.0162 0.0329 0.0397
Brugia malayi protein-tyrosine kinase 0.1029 0.2218 0.4176
Loa Loa (eye worm) latrophilin receptor protein 2 0.0158 0.0321 0.0387
Schistosoma mansoni heat shock protein 0.0033 0.0048 0.0048
Echinococcus granulosus neuropeptide s receptor 0.0504 0.1074 0.1296
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.0158 0.032 0.0387
Mycobacterium ulcerans hypothetical protein 0.0112 0.022 0.2697
Schistosoma mansoni jumonji domain containing protein 0.0046 0.0077 0.0077
Echinococcus multilocularis growth factor receptor bound protein 2 0.0321 0.0674 0.0814
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0014 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0061 0.0752
Brugia malayi bone morphogenetic protein type 1 receptor 0.0046 0.0077 0.0144
Schistosoma mansoni coup transcription factor 0.0014 0.0005 0.0005
Schistosoma mansoni jumonji/arid domain-containing protein 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0000011266 0.0000011266
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0115 0.0138
Schistosoma mansoni hypothetical protein 0.0158 0.0321 0.0321
Schistosoma mansoni protein tyrosine kinase 0.0046 0.0077 0.0077
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0077 0.1353
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0046 0.0077 0.041
Toxoplasma gondii propionate-CoA ligase 0.0014 0.0005 0.0076
Schistosoma mansoni tar DNA-binding protein 0.0173 0.0352 0.0352
Echinococcus multilocularis fmrfamide receptor 0.0125 0.0249 0.03
Echinococcus granulosus ornithine aminotransferase 0.0016 0.001 0.0013
Mycobacterium tuberculosis Probable thioesterase TesA 0.0014 0.0007 0.0275
Toxoplasma gondii type I fatty acid synthase, putative 0.0012 0.0002 0.0034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0174
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0039 0.0061 0.0061
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0125 0.0249 0.0249
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0046 0.0077 0.0093
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Loa Loa (eye worm) hypothetical protein 0.0185 0.0378 0.0457
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Echinococcus granulosus tyrosine kinase 0.0209 0.043 0.052
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Plasmodium falciparum ataxin-2 like protein, putative 0.0035 0.0051 0.1336
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0112 0.022 0.2697
Echinococcus multilocularis neuropeptide receptor A26 0.0504 0.1074 0.1296
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0017 0.0013 0.016
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0018 0.0014 0.0014
Echinococcus multilocularis carbonic anhydrase 0.0127 0.0253 0.0306
Mycobacterium ulcerans Type I modular polyketide synthase 0.0017 0.0013 0.016
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0022 0.0024 0.0125
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.001 0.0174
Loa Loa (eye worm) PHD-finger family protein 0.0018 0.0014 0.0017
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0022 0.0024 0.0029
Echinococcus multilocularis heat shock protein 90 0.0028 0.0038 0.0045
Brugia malayi cytokine inducible SH2-containing protein 5 0.0162 0.0329 0.062
Mycobacterium ulcerans glutaminase 0.0386 0.0816 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Brugia malayi Polyprenyl synthetase family protein 0.0124 0.0245 0.0462
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.0093
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0126 0.0251 0.0303
Echinococcus multilocularis Protein lozenge 0.0054 0.0094 0.0114
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0046 0.0077 0.0144
Loa Loa (eye worm) hypothetical protein 0.0039 0.0061 0.0074
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Echinococcus multilocularis neuropeptide Y receptor 0.0125 0.0249 0.03
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0332 0.0699 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0125 0.0249 0.03
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0094 0.018 0.0217
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Brugia malayi neuropeptide F receptor 0.0125 0.0249 0.0468
Schistosoma mansoni hypothetical protein 0.1036 0.2232 0.2232
Trichomonas vaginalis steroid dehydrogenase, putative 0.0011 0 0.0003
Schistosoma mansoni hypothetical protein 0.004 0.0063 0.0063
Onchocerca volvulus 0.0159 0.0322 0.3491
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.0249 0.03
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Brugia malayi G-protein coupled receptor 0.0125 0.0249 0.0468
Echinococcus granulosus geminin 0.1036 0.2232 0.2695
Loa Loa (eye worm) hypothetical protein 0.006 0.0106 0.0128
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Onchocerca volvulus 0.0046 0.0077 0.083
Entamoeba histolytica hypothetical protein 0.0128 0.0254 0.1361
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0203 0.8283
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0014 0.0005 0.0005
Brugia malayi Variant SH3 domain containing protein 0.0158 0.032 0.0603
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0031 0.0043 0.1745
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0014 0.0005 0.0007
Plasmodium falciparum plasmepsin X 0.0185 0.0378 1
Brugia malayi Thioredoxin reductase 0.0046 0.0075 0.0142
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0039 0.0061 0.0752
Entamoeba histolytica hypothetical protein 0.0158 0.032 0.1718
Loa Loa (eye worm) hypothetical protein 0.0051 0.0087 0.0105
Echinococcus granulosus allatostatin A receptor 0.0125 0.0249 0.03
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0046 0.0077 0.0093
Echinococcus multilocularis protein kinase 0.0046 0.0077 0.0093
Echinococcus multilocularis tensin 0.0162 0.0329 0.0397
Echinococcus multilocularis endophilin A3 0.0158 0.032 0.0387
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0501 0.1066 0.1287
Echinococcus granulosus importin subunit beta 1 0.0019 0.0017 0.002
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0014 0.0006 0.0007
Echinococcus granulosus neuropeptides capa receptor 0.0125 0.0249 0.03
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0039 0.0061 0.1077
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Plasmodium falciparum endoplasmin, putative 0.0024 0.0028 0.0737
Brugia malayi Variant SH3 domain containing protein 0.0158 0.032 0.0603
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0128 0.0254 0.0478
Echinococcus granulosus Aminotransferase class III 0.0016 0.001 0.0013
Loa Loa (eye worm) TK/CSK protein kinase 0.0046 0.0077 0.0093
Trypanosoma brucei PAB1-binding protein , putative 0.0035 0.0051 0.0891
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0075 0.1988
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0039 0.0061 0.0074
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0014 0.0005 0.0005
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0125 0.0249 0.03
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0077 0.094
Echinococcus granulosus hypothetical protein 0.0125 0.0249 0.03
Loa Loa (eye worm) melatonin receptor type 1A 0.0125 0.0249 0.03
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0119 0.1464
Echinococcus granulosus protein tyrosine kinase 0.0046 0.0077 0.0093
Entamoeba histolytica hypothetical protein 0.0046 0.0077 0.041
Toxoplasma gondii heat shock protein 90, putative 0.0033 0.0048 0.0686
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0016 0.001 0.0148
Schistosoma mansoni steroid hormone receptor ad4bp 0.0014 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0077 0.0093
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0022 0.0024 0.0254
Plasmodium vivax sphingomyelin synthase 1, putative 0.0128 0.0254 0.6716
Echinococcus granulosus biogenic amine 5HT receptor 0.173 0.3744 0.452
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Loa Loa (eye worm) hypothetical protein 0.0128 0.0254 0.0307
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Plasmodium vivax ataxin-2 like protein, putative 0.0035 0.0051 0.1336
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0026 0.0032 0.1294
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0124 0.0245 0.3005
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0051
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0127 0.0253 0.0477
Brugia malayi Immunoglobulin I-set domain containing protein 0.0046 0.0077 0.0144
Echinococcus granulosus intersectin 2 0.0158 0.032 0.0387
Schistosoma mansoni tyrosine kinase 0.0196 0.0403 0.0403
Toxoplasma gondii aspartyl protease ASP3 0.0185 0.0378 0.5411
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0052
Schistosoma mansoni hypothetical protein 0.0119 0.0236 0.0236
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0185 0.0378 0.0378
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0031 0.0044 0.0053
Echinococcus granulosus SH2 domain containing protein 7 0.0162 0.0329 0.0397
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0077 0.3356
Echinococcus multilocularis protein KINase family member (kin 25) 0.0046 0.0077 0.0093
Plasmodium vivax tyrosine kinase-like protein, putative 0.0046 0.0077 0.2023
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0039 0.0061 0.0074
Echinococcus granulosus neuropeptide Y receptor 0.0125 0.0249 0.03
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0007
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0048 0.0842
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0031 0.0044 0.1899
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus multilocularis somatostatin receptor 0.0125 0.0249 0.03
Mycobacterium ulcerans acetylornithine aminotransferase 0.0016 0.001 0.0124
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0011 0.0000011266 0.0000013602
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0017 0.0012 0.0485
Entamoeba histolytica hypothetical protein 0.0046 0.0077 0.041
Echinococcus multilocularis protein kinase 0.0046 0.0077 0.0093
Toxoplasma gondii Hsp90 domain-containing protein 0.0126 0.025 0.3576
Entamoeba histolytica hypothetical protein 0.0046 0.0077 0.041
Schistosoma mansoni tar DNA-binding protein 0.0173 0.0352 0.0352
Onchocerca volvulus 0.0102 0.0198 0.2143
Loa Loa (eye worm) TK/FER protein kinase 0.0209 0.043 0.052
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0121 0.0239 0.2594
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Brugia malayi Protein kinase domain containing protein 0.016 0.0325 0.0611
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0016 0.001 0.0124
Brugia malayi nuclear receptor NHR-88 0.0014 0.0005 0.001
Loa Loa (eye worm) heat shock protein 90 0.0033 0.0048 0.0058
Brugia malayi RNA, U transporter 1 0.0053 0.0092 0.0173
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0031 0.0044 0.0763
Leishmania major GTP-binding protein, putative 0.0014 0.0006 0.0096
Toxoplasma gondii heat shock protein HSP90 0.0033 0.0048 0.0686
Mycobacterium leprae Polyketide synthase Pks13 0.0026 0.0032 0.1388
Mycobacterium ulcerans L-lysine aminotransferase 0.0016 0.001 0.0124
Schistosoma mansoni voltage-gated potassium channel 0.0066 0.0119 0.0119
Schistosoma mansoni hypothetical protein 0.1036 0.2232 0.2232
Trypanosoma cruzi hypothetical protein, conserved 0.0158 0.032 0.5651
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0271 0.0567 0.1067
Brugia malayi Protein kinase domain containing protein 0.0209 0.043 0.081
Leishmania major hypothetical protein, conserved 0.0046 0.0077 0.1349
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1188 0.2563 0.3094
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0077 0.0093
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0031 0.0044 0.177
Echinococcus multilocularis biogenic amine (5HT) receptor 0.173 0.3744 0.452
Echinococcus multilocularis insulin receptor 0.0094 0.018 0.0217
Loa Loa (eye worm) TK protein kinase 0.0046 0.0077 0.0093
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0014 0.0006 0.0248
Brugia malayi isocitrate dehydrogenase 0.0031 0.0044 0.0083
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Brugia malayi Variant SH3 domain containing protein 0.0158 0.032 0.0603
Brugia malayi Dopamine receptor protein 1 0.0125 0.0249 0.0468
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.0093
Leishmania major polyprenyl synthase, putative 0.0031 0.0044 0.0766
Echinococcus multilocularis neuropeptide FF receptor 2 0.0125 0.0249 0.03
Brugia malayi MH2 domain containing protein 0.0018 0.0015 0.0029
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0077 0.0093
Brugia malayi Variant SH3 domain containing protein 0.0158 0.032 0.0603
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0005 0.0065
Schistosoma mansoni smad1 5 8 and 0.0018 0.0015 0.0015
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0077 0.041
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.0249 0.03
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Loa Loa (eye worm) hypothetical protein 0.0434 0.0921 0.1112
Echinococcus multilocularis protein tyrosine kinase 0.0046 0.0077 0.0093
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0031 0.0044 0.0766
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0271 0.0567 1
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0059 0.0104 0.0126
Entamoeba histolytica receptor protein kinase, putative 0.0046 0.0077 0.041
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Echinococcus granulosus hypothetical protein 0.0162 0.0329 0.0397
Trichomonas vaginalis glutaminase, putative 0.0386 0.0816 1
Leishmania major solanesyl-diphosphate synthase, putative 0.0031 0.0044 0.0766
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0005 0.0089
Leishmania major phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0128 0.0254 0.4479
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0125 0.0249 0.0468
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0039 0.0061 0.1077
Brugia malayi serine/threonine-protein kinase plk-2 0.0066 0.0119 0.0225
Plasmodium falciparum protein kinase, putative 0.0047 0.0078 0.2062
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0125 0.0249 0.0249
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0044 0.179
Echinococcus multilocularis serotonin receptor 0.0644 0.1379 0.1665
Onchocerca volvulus 0.0046 0.0077 0.083
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0162 0.0329 0.0397
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0187 0.0352
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0015 0.0009 0.0109
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.0031 0.0043 0.1872
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0039 0.0061 0.1077
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0061 0.1077
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0015 0.0009 0.0011
Echinococcus multilocularis G-protein coupled receptor, putative 0.0125 0.0249 0.03
Schistosoma mansoni opsin-like receptor 0.0125 0.0249 0.0249
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.001 0.0174
Brugia malayi heat shock protein 90 0.0033 0.0048 0.009
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0162 0.0329 0.0397
Brugia malayi C-terminal src kinase protein 1 0.0046 0.0077 0.0144
Brugia malayi Melatonin receptor type 1A 0.0125 0.0249 0.0468
Leishmania major protein kinase, putative 0.0046 0.0077 0.1349
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0128 0.0254 0.4479
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0127 0.0253 0.0477
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0124 0.0245 0.4326
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0125 0.0249 0.0468
Schistosoma mansoni jumonji/arid domain-containing protein 0.0023 0.0026 0.0026
Loa Loa (eye worm) CAMK/PIM protein kinase 0.016 0.0325 0.0392
Echinococcus granulosus tyrosine protein kinase Fyn 0.1188 0.2563 0.3094
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0047 0.1914
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0162 0.0329 0.0397
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0031 0.0044 0.0053
Schistosoma mansoni hypothetical protein 0.0158 0.0321 0.0321
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0434 0.0921 0.1112
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0124 0.0245 1
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.0158 0.032 0.0387
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0015 0.0018
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0051 0.2082
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0066 0.0119 0.0144
Brugia malayi SH2 domain containing protein 0.0162 0.0329 0.062
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0018 0.0016 0.0628
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0046 0.0077 0.094
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0005 0.0007
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0015 0.0009 0.0011
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Schistosoma mansoni amine GPCR 0.0125 0.0249 0.0249
Echinococcus granulosus tyrosine protein kinase Fyn 0.1188 0.2563 0.3094
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0044 0.0083
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0046 0.0077 0.0093
Trichomonas vaginalis heat shock protein, putative 0.0019 0.0018 0.0216
Giardia lamblia Heat shock protein HSP 90-alpha 0.0033 0.0048 0.0701
Entamoeba histolytica hypothetical protein 0.0158 0.032 0.1718
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0086 0.3488
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0039 0.0061 0.1615
Onchocerca volvulus 0.0046 0.0077 0.083
Trypanosoma cruzi importin beta-1 subunit, putative 0.0015 0.0009 0.015
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0014 0.0006 0.0251
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Echinococcus multilocularis signal transduction protein lnk realted 0.0162 0.0329 0.0397
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0031 0.0044 0.0233
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0125 0.0249 0.03
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Loa Loa (eye worm) oxidoreductase 0.0014 0.0005 0.0006
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0039 0.0061 0.0074
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.001 0.0145
Echinococcus granulosus carbonic anhydrase 0.0127 0.0253 0.0306
Schistosoma mansoni tensin-related 0.0162 0.0329 0.0329
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Schistosoma mansoni ran 0.0014 0.0006 0.0006
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0005 0.0089
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0151 0.0304 0.0368
Trypanosoma brucei heat shock protein, putative 0.0033 0.0048 0.0842
Trypanosoma brucei conserved protein 0.0158 0.032 0.5651
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.0093
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0066 0.0119 0.0144
Onchocerca volvulus 0.0125 0.0249 0.2695
Loa Loa (eye worm) hypothetical protein 0.0035 0.0051 0.0062
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Trypanosoma brucei inositol phosphorylceramide synthase 0.0128 0.0254 0.4479
Echinococcus multilocularis thyroid hormone receptor alpha 0.0014 0.0005 0.0007
Trypanosoma brucei GMP reductase 0.0059 0.0104 0.1832
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Schistosoma mansoni biogenic amine (5HT) receptor 0.0644 0.1379 0.1379
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0000011266 0.0000013602
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0128 0.0254 0.0478
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0000011266 0.0000013602
Plasmodium falciparum plasmepsin IX 0.0185 0.0378 1
Schistosoma mansoni growth factor receptor-bound protein 0.0321 0.0674 0.0674
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Echinococcus granulosus raf serine:threonine protein kinase 0.0046 0.0077 0.0093
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0031 0.0044 0.0532
Loa Loa (eye worm) SH2 domain-containing protein 0.0162 0.0329 0.0397
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0046 0.0077 0.0093
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0047 0.0078 0.0094
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0174
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0015 0.0009 0.0388
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0124 0.0245 0.6486
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0187 0.0226
Schistosoma mansoni eps8-related protein 0.0158 0.032 0.032
Schistosoma mansoni eyes absent homolog 0.006 0.0106 0.0106
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0046 0.0077 0.0093
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0075 0.0091
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0044 0.0053
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0014 0.0006 0.0096
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0124 0.0245 0.6486
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0000011266 0.0000011266
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0044 0.0774
Loa Loa (eye worm) transcription factor SMAD2 0.0267 0.0558 0.0674
Echinococcus multilocularis importin subunit beta 1 0.0019 0.0017 0.002
Brugia malayi Dehydrogenases, short chain protein 30 0.0011 0 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0000011266 0.0000013602
Leishmania major guanosine monophosphate reductase 0.0059 0.0104 0.1832
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0015 0.0009 0.0109
Onchocerca volvulus 0.0158 0.032 0.3475
Loa Loa (eye worm) hypothetical protein 0.0342 0.0721 0.0871
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.001 0.0689
Echinococcus granulosus SH2 domain containing adapter protein F 0.0162 0.0329 0.0397
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0004 0.0008
Brugia malayi Latrophilin receptor protein 2 0.0158 0.0321 0.0604
Entamoeba histolytica hypothetical protein 0.0158 0.032 0.1718
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0104 0.1269
Echinococcus multilocularis neuropeptide Y receptor 0.0125 0.0249 0.03
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Echinococcus multilocularis SH2 domain containing protein 7 0.0162 0.0329 0.0397
Echinococcus granulosus heat shock protein 90 0.0033 0.0048 0.0058
Onchocerca volvulus Putative cortactin 0.0158 0.032 0.3475
Schistosoma mansoni opsin-like receptor 0.0125 0.0249 0.0249
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0124 0.0245 0.3511
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Brugia malayi AKH receptor 0.0125 0.0249 0.0468
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0077 0.0077
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0015 0.0018
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Echinococcus multilocularis tyrosine protein kinase Abl 0.1745 0.3778 0.4561
Echinococcus granulosus signal transduction protein lnk realted 0.0162 0.0329 0.0397
Onchocerca volvulus Neuropeptide F receptor homolog 0.0125 0.0249 0.2695
Trichomonas vaginalis CAMK family protein kinase 0.0033 0.0047 0.058
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0007
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0038 0.046
Trypanosoma brucei carbonic anhydrase-like protein 0.0271 0.0567 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0127 0.0253 0.0477
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0128 0.0254 0.3114
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.0093
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0185 0.0378 0.0457
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0031 0.0044 0.1893
Echinococcus multilocularis g-protein coupled receptor 0.0125 0.0249 0.03
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0144 0.1758
Entamoeba histolytica unconventional myosin IB 0.0158 0.032 0.1718
Loa Loa (eye worm) serine/threonine protein kinase 0.0046 0.0077 0.0093
Echinococcus multilocularis tyrosine protein kinase Blk 0.1029 0.2218 0.2678
Onchocerca volvulus 0.0209 0.043 0.4669
Toxoplasma gondii aspartyl protease 0.0185 0.0378 0.5411
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0064 0.0115 0.2017
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0185 0.0378 0.0457
Entamoeba histolytica hypothetical protein 0.0158 0.032 0.1718
Onchocerca volvulus Tyrosine kinase homolog 0.0046 0.0077 0.083
Echinococcus granulosus epidermal growth factor receptor 0.0126 0.0251 0.0303
Echinococcus granulosus tyrosine protein kinase 0.0046 0.0077 0.0093
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0016 0.001 0.0412
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0003 0.0029
Onchocerca volvulus 0.0046 0.0077 0.083
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0115 0.0216
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Echinococcus granulosus lysine specific demethylase 5A 0.0023 0.0026 0.0031
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0162 0.0329 0.0397
Echinococcus granulosus integrin linked protein kinase 0.0046 0.0077 0.0093
Plasmodium falciparum plasmepsin III 0.0185 0.0378 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1188 0.2563 0.3094
Plasmodium falciparum protein kinase, putative 0.0046 0.0077 0.2023
Echinococcus granulosus cpg binding protein 0.0025 0.003 0.0036
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0005 0.0089
Brugia malayi Tachykinin-like peptides receptor 99D 0.0125 0.0249 0.0468
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Plasmodium falciparum glutathione reductase 0.0046 0.0075 0.1988
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Brugia malayi G protein-coupled receptor F59B2.13 0.0125 0.0249 0.0468
Mycobacterium ulcerans polyketide synthase 0.0018 0.0016 0.0189
Plasmodium falciparum carbonic anhydrase 0.0127 0.0253 0.6696
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0059 0.0104 0.0196
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Leishmania major inosine-5-monophosphate dehydrogenase 0.0059 0.0104 0.1832
Echinococcus multilocularis tyrosine kinase 0.0209 0.043 0.052
Echinococcus granulosus tyrosine protein kinase HCK 0.0867 0.1864 0.2251
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0014 0.0005 0.0007
Brugia malayi ORL1-like opioid receptor 0.0125 0.0249 0.0468
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0016 0.001 0.0412
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0066 0.0119 0.0225
Echinococcus granulosus heat shock protein 0.0033 0.0048 0.0058
Loa Loa (eye worm) TK/FER protein kinase 0.0209 0.043 0.052
Echinococcus multilocularis neuropeptide receptor 0.0125 0.0249 0.03
Loa Loa (eye worm) TK/ROR protein kinase 0.0046 0.0077 0.0093
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0144 1
Echinococcus granulosus FTZ F1 alpha 0.0014 0.0005 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0048 0.0842
Echinococcus multilocularis lysine specific demethylase 5A 0.0022 0.0023 0.0027
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0000011266 0.0000011266
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0039 0.0061 0.0074
Onchocerca volvulus 0.0125 0.0249 0.2695
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Leishmania major heat shock protein 83-1 0.0033 0.0048 0.0842
Loa Loa (eye worm) hypothetical protein 0.0462 0.0983 0.1187
Loa Loa (eye worm) runx1 0.0054 0.0094 0.0114
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0014 0.0005 0.0007
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0125 0.0249 0.03
Echinococcus multilocularis endoplasmin 0.0031 0.0044 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0205 0.0422 0.0422
Echinococcus granulosus endoplasmin 0.0031 0.0044 0.0053
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0077 0.0145
Entamoeba histolytica hypothetical protein 0.0128 0.0254 0.1361
Echinococcus multilocularis nostrin 0.0158 0.032 0.0387
Brugia malayi jmjC domain containing protein 0.0023 0.0026 0.0048
Entamoeba histolytica hypothetical protein, conserved 0.0158 0.032 0.1718
Entamoeba histolytica tyrosine kinase, putative 0.0046 0.0077 0.041
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Schistosoma mansoni biogenic amine receptor 0.0125 0.0249 0.0249
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0158 0.0321 0.0604
Schistosoma mansoni run and tbc1 domain containing 0.0158 0.032 0.032
Onchocerca volvulus 0.0209 0.043 0.4669
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0031 0.0044 0.0053
Trichomonas vaginalis protein kinase atn1, putative 0.0046 0.0077 0.094
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0111 0.0218 0.2665
Schistosoma mansoni protein kinase 0.0047 0.0078 0.0078
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0125 0.0249 0.03
Echinococcus multilocularis g protein coupled receptor 0.0125 0.0249 0.03
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0011 0 0.0001
Onchocerca volvulus 0.0125 0.0249 0.2695
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0066 0.0814
Loa Loa (eye worm) hypothetical protein 0.0158 0.032 0.0387
Echinococcus granulosus voltage gated potassium channel 0.0011 0.0000011266 0.0000013602
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0046 0.0077 0.0093
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0115 0.1401
Brugia malayi Guanylate kinase family protein 0.0158 0.032 0.0603
Schistosoma mansoni amine GPCR 0.0125 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Echinococcus multilocularis snurportin 1 0.0201 0.0413 0.0498
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.001 0.0689
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0 0.0001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0174
Brugia malayi hypothetical protein 0.0046 0.0077 0.0144
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0185 0.0378 0.0378
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1188 0.2563 0.3094
Leishmania major hypothetical protein, conserved 0.0035 0.0051 0.0891
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0162 0.0329 0.0397
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0011 0.0000011266 0.0000013602
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0005 0.0062
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0048 0.0842
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0077 0.0093
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0325 0.0325
Brugia malayi Retinol dehydrogenase 12 0.0011 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.002
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0005 0.0206
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.1615
Brugia malayi hypothetical protein 0.0185 0.0378 0.0712
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0323 0.068 0.0821
Loa Loa (eye worm) hypothetical protein 0.0158 0.032 0.0387
Brugia malayi Protein kinase domain containing protein 0.0046 0.0077 0.0144
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0046 0.0077 0.0093
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.2449 0.5311 1
Schistosoma mansoni amine GPCR 0.0125 0.0249 0.0249
Schistosoma mansoni voltage-gated potassium channel 0.0066 0.0119 0.0119
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0039 0.0061 0.0061
Trypanosoma brucei heat shock protein, putative 0.0033 0.0048 0.0842
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0014 0.0005 0.001
Plasmodium vivax aspartyl proteinase, putative 0.0185 0.0378 1
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0035 0.0051 0.0061
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0039 0.0061 0.0061
Brugia malayi Cyclic-nucleotide gated cation channel 0.0011 0.0000011266 0.0000021211
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.1077
Echinococcus multilocularis NCK adaptor protein 0.0321 0.0674 0.0814
Brugia malayi hypothetical protein 0.0162 0.0329 0.062
Onchocerca volvulus 0.0125 0.0249 0.2695
Brugia malayi Peripheral plasma membrane protein CASK 0.0158 0.032 0.0603
Echinococcus granulosus rhodopsin orphan GPCR 0.0125 0.0249 0.03
Toxoplasma gondii carbonyl reductase 1, putative 0.0011 0 0.0003
Plasmodium vivax ornithine aminotransferase, putative 0.0016 0.001 0.0267
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0014 0.0006 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.032 0.3927
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0039 0.0061 0.1077
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0015 0.0009 0.0108
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0056 0.0067
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0077 0.094
Brugia malayi protein-tyrosine kinase 0.0158 0.032 0.0603
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.0093
Schistosoma mansoni cathepsin D (A01 family) 0.0185 0.0378 0.0378
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0014 0.0005 0.0062
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0005 0.0005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0125 0.0249 0.0249
Plasmodium vivax phosphodiesterase gamma, putative 0.0039 0.0061 0.1615
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0086 0.0104
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0061 0.0877
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0077 0.041
Schistosoma mansoni glutaminase 0.0386 0.0816 0.0816
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0151 0.0304 0.0304
Brugia malayi RE15519p 0.0125 0.0249 0.0468
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0075 0.0091
Plasmodium vivax aspartyl protease, putative 0.0185 0.0378 1
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0077 0.0093
Brugia malayi glutaminase DH11.1 0.0386 0.0816 0.1536
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0077 0.0411
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0039 0.0061 0.0074
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0005 0.0089
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0046 0.0077 0.0093
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1188 0.2563 0.3094
Echinococcus multilocularis SH2 motif 0.0162 0.0329 0.0397
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0015 0.0009 0.0009
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.001 0.0174
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0044 0.0044
Loa Loa (eye worm) TK/FAK protein kinase 0.0046 0.0077 0.0093
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0061 0.1077
Schistosoma mansoni hypothetical protein 0.0162 0.0329 0.0329
Loa Loa (eye worm) hypothetical protein 0.0125 0.0249 0.03
Echinococcus granulosus tyrosine protein kinase Src64B 0.1188 0.2563 0.3094
Schistosoma mansoni protein kinase 0.0046 0.0077 0.0077
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0039 0.0061 0.1077
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Entamoeba histolytica protein kinase, putative 0.0046 0.0077 0.041
Schistosoma mansoni smad 0.0018 0.0015 0.0015
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0011 0 0.0003
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0046 0.0077 0.094
Echinococcus multilocularis ephrin type A receptor 4 A 0.0046 0.0077 0.0093
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0048 0.0256
Brugia malayi hypothetical protein 0.0119 0.0236 0.0444
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.1615
Loa Loa (eye worm) TK/FER protein kinase 0.0046 0.0077 0.0093
Brugia malayi MH1 domain containing protein 0.0018 0.0015 0.0029
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0162 0.0329 0.0397
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0039 0.0061 0.0752
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0017 0.0013 0.0025
Onchocerca volvulus 0.0125 0.0249 0.2695
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0066 0.008
Echinococcus granulosus tachykinin peptides receptor 99D 0.0125 0.0249 0.03
Schistosoma mansoni biogenic amine (5HT) receptor 0.173 0.3744 0.3744
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0046 0.0077 0.041
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0000011266 0.0000013602
Loa Loa (eye worm) hypothetical protein 0.0162 0.0329 0.0397
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0039 0.0061 0.0752
Brugia malayi Dopamine receptor 0.0125 0.0249 0.0468
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0144 0.0144
Toxoplasma gondii oxidoreductase, putative 0.0011 0 0.0003
Schistosoma mansoni apoptosis stimulating of P53 0.0158 0.032 0.032
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0323 0.068 0.0821
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0174
Echinococcus granulosus g protein coupled receptor 0.0125 0.0249 0.03
Schistosoma mansoni suppressor of cytokine signaling 0.0162 0.0329 0.0329
Brugia malayi Variant SH3 domain containing protein 0.0321 0.0674 0.1269
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0005 0.001
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0014 0.0006 0.0081

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2.7 uM Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysis ChEMBL. 23610597
IC50 (binding) = 4.2 uM Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphosphate as substrate preincubated with enzyme for 30 mins by spectrophotometric analysis ChEMBL. 23610597
IC50 (functional) = 44 uM Inhibition of Plasmodium falciparum growth after 72 hrs by LDH assay ChEMBL. 23610597

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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