Detailed information for compound 264099

Basic information

Technical information
  • TDR Targets ID: 264099
  • Name: (7R,8R)-7-benzhydryl-N-[(2-chlorophenyl)methy l]-1-azabicyclo[2.2.2]octan-8-amine
  • MW: 416.986 | Formula: C27H29ClN2
  • H donors: 1 H acceptors: 0 LogP: 6.02 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccccc1CN[C@@H]1C2CCN([C@@H]1C(c1ccccc1)c1ccccc1)CC2
  • InChi: 1S/C27H29ClN2/c28-24-14-8-7-13-23(24)19-29-26-22-15-17-30(18-16-22)27(26)25(20-9-3-1-4-10-20)21-11-5-2-6-12-21/h1-14,22,25-27,29H,15-19H2/t26-,27-/m1/s1
  • InChiKey: LURXNRSWKKLLDE-KAYWLYCHSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R,3R)-2-benzhydryl-N-[(2-chlorophenyl)methyl]quinuclidin-3-amine
  • (2R,3R)-2-benzhydryl-N-[(2-chlorophenyl)methyl]-3-quinuclidinamine
  • [(2R,3R)-2-benzhydrylquinuclidin-3-yl]-(2-chlorobenzyl)amine
  • 3-(2-chlorobenzylamino)-2-benzhydrylquinuclidine
  • (7R,8R)-N-[(2-chlorophenyl)methyl]-7-[di(phenyl)methyl]-1-azabicyclo[2.2.2]octan-8-amine
  • (2R,3R)-N-[(2-chlorophenyl)methyl]-2-[di(phenyl)methyl]quinuclidin-3-amine
  • (2R,3R)-N-[(2-chlorophenyl)methyl]-2-[di(phenyl)methyl]-3-quinuclidinamine
  • (2-chlorobenzyl)-[(2R,3R)-2-[di(phenyl)methyl]quinuclidin-3-yl]amine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Cavia porcellus Neurokinin 1 receptor Starlite/ChEMBL No references
Rattus norvegicus Neurokinin 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K04224 tachykinin receptor 3, putative Get druggable targets OG5_137770 All targets in OG5_137770
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis thyrotropin releasing hormone receptor Neurokinin 1 receptor   407 aa 342 aa 22.2 %
Schistosoma mansoni neuropeptide F-like receptor Neurokinin 1 receptor   407 aa 333 aa 21.0 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Neurokinin 1 receptor   407 aa 352 aa 25.3 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Neurokinin 1 receptor   407 aa 373 aa 22.8 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Neurokinin 1 receptor   407 aa 387 aa 18.1 %
Echinococcus granulosus thyrotropin releasing hormone receptor Neurokinin 1 receptor   407 aa 341 aa 22.0 %
Echinococcus multilocularis allatostatin A receptor Neurokinin 1 receptor   407 aa 347 aa 24.8 %
Echinococcus granulosus allatostatin A receptor Neurokinin 1 receptor   407 aa 347 aa 24.8 %
Schistosoma japonicum ko:K04255 opsin 4 (melanopsin), putative Neurokinin 1 receptor   407 aa 339 aa 20.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.117 0.0749 0.7003
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.0067 0.3723
Entamoeba histolytica acyl-CoA synthetase, putative 0.0022 0.0004 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0022 0.0004 0.0205
Mycobacterium ulcerans esterase/lipase LipP 0.0101 0.0055 0.3052
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0044 0.0018 0.0427
Loa Loa (eye worm) steroid hormone receptor 0.0026 0.0007 0.0058
Trichomonas vaginalis esterase, putative 0.0101 0.0055 0.0711
Toxoplasma gondii HEAT repeat-containing protein 0.0156 0.0091 0.1224
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0044 0.0018 0.0971
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0001 0.0021
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0047 0.002 0.0272
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0232 0.014 0.0398
Trichomonas vaginalis PIKK family atypical protein kinase 0.068 0.0431 0.574
Toxoplasma gondii exonuclease III APE 0.0039 0.0015 0.0204
Brugia malayi steroid hormone receptor 0.0026 0.0007 0.0073
Entamoeba histolytica acyl-CoA synthetase, putative 0.0022 0.0004 0.0028
Schistosoma mansoni hypothetical protein 0.0126 0.0072 0.0664
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0006 0.0051
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0044 0.0018 0.0427
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0035 0.0012 0.0011
Brugia malayi cytochrome P450 0.0044 0.0018 0.022
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0044 0.0018 0.0221
Plasmodium vivax sentrin-specific protease 1, putative 0.005 0.0022 0.126
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0044 0.0018 0.0427
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0126 0.0072 0.0071
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0158 0.0092 0.0855
Echinococcus multilocularis g protein coupled receptor 0.0126 0.0072 0.0071
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.8378
Loa Loa (eye worm) hypothetical protein 0.0065 0.0032 0.0293
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0561 0.0354 0.3306
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0001 0.005
Echinococcus granulosus PHD finger protein rhinoceros 0.0048 0.002 0.002
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.8057
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.2121
Brugia malayi G protein-coupled receptor F59B2.13 0.0126 0.0072 0.0925
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0126 0.0072 0.0925
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0044 0.0018 0.0971
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0101 0.0055 0.1341
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0024 0.0005 0.0004
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0044 0.0018 0.0047
Loa Loa (eye worm) transcription factor SMAD2 0.026 0.0158 0.1477
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0044 0.0018 0.0427
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0019 0.0002 0.0002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0026 0.0007 0.0006
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0232 0.014 0.1846
Loa Loa (eye worm) phosphatidylinositol 3 0.0232 0.014 0.1305
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0283 0.0174 0.2297
Schistosoma mansoni hypothetical protein 0.0316 0.0195 0.1815
Schistosoma mansoni neuropeptide receptor 0.0126 0.0072 0.0664
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0015 0.0014
Onchocerca volvulus 0.0135 0.0077 0.4738
Schistosoma mansoni histamine h1 receptor 0.0126 0.0072 0.0664
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0034
Echinococcus granulosus tm gpcr rhodopsin 0.0126 0.0072 0.0071
Schistosoma mansoni hypothetical protein 0.035 0.0217 0.2024
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0026 0.0325
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0232 0.014 0.0139
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0007 0.0057
Echinococcus multilocularis Zinc finger, PHD finger 0.0283 0.0174 0.0173
Loa Loa (eye worm) phosphatidylinositol 3 0.117 0.0749 0.7004
Echinococcus multilocularis beta LACTamase domain containing family member 0.0101 0.0055 0.0054
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0232 0.014 0.1854
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0047 0.002 0.0054
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.117 0.0749 0.0748
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0005 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0026 0.0007 0.0073
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0017 0.0197
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0032 0.0297
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0033
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0011 0.0142
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.005 0.0022 0.0267
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0021 0.002
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0048 0.0021 0.0499
Onchocerca volvulus 0.0126 0.0072 0.4394
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0011 0.1307
Schistosoma mansoni hypothetical protein 0.0126 0.0072 0.0664
Loa Loa (eye worm) neuropeptide F receptor 0.0126 0.0072 0.0665
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0044 0.0018 0.0427
Mycobacterium tuberculosis Probable lipase LipE 0.0101 0.0055 0.1341
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0004 0.0098
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0022 0.0058
Echinococcus multilocularis serine protein kinase ATM 0.0664 0.0421 0.042
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0025 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni ran 0.0091 0.0049 0.0453
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.117 0.0749 0.2058
Chlamydia trachomatis DNA ligase 0.0019 0.0002 0.0363
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0047 0.002 0.0252
Echinococcus granulosus geminin 0.035 0.0217 0.0216
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0004 0.0205
Entamoeba histolytica transcription factor BTF3, putative 0.0022 0.0004 0.0028
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0283 0.0174 0.162
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0063 0.0582
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0044 0.0018 0.0971
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0232 0.014 0.1824
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0398 0.0248 0.3292
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0015 0.0359
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0283 0.0174 0.2297
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0664 0.0421 0.1204
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.115 0.0737 0.9832
Schistosoma mansoni hypothetical protein 0.035 0.0217 0.2024
Brugia malayi isocitrate dehydrogenase 0.0018 0.0001 0.0003
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0048 0.002 0.0187
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.117 0.0749 0.0748
Onchocerca volvulus 0.0126 0.0072 0.4394
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0448 0.028 0.0279
Echinococcus multilocularis neuropeptide FF receptor 2 0.0126 0.0072 0.0071
Schistosoma mansoni neuropeptide receptor 0.0126 0.0072 0.0664
Echinococcus multilocularis somatostatin receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0039 0.0015 0.0136
Loa Loa (eye worm) phosphatidylinositol 3 0.115 0.0737 0.6886
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0232 0.014 0.8054
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Toxoplasma gondii ATPase, AAA family protein 0.0019 0.0002 0.0028
Mycobacterium tuberculosis Conserved protein 0.0101 0.0055 0.1341
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0026 0.0007 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0026 0.0007 0.0006
Echinococcus multilocularis lamin dm0 0.0135 0.0077 0.0076
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.0026 0.0025
Echinococcus multilocularis neuropeptide receptor 0.0126 0.0072 0.0071
Plasmodium falciparum thioredoxin reductase 0.0136 0.0078 0.447
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0073 0.0037 0.0502
Trypanosoma cruzi hypothetical protein, conserved 0.5383 0.3485 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0051 0.0023 0.0288
Onchocerca volvulus 0.0022 0.0004 0.0103
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0007 0.0057
Entamoeba histolytica hypothetical protein 0.0022 0.0004 0.0028
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0232 0.014 0.1846
Loa Loa (eye worm) CHromoDomain protein family member 0.0033 0.0011 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0044 0.0018 0.0427
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0002 0.0002
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.116 0.0743 0.2041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0283 0.0174 0.0173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0668 0.0423 0.5638
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0094 0.0051 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0418 0.0261 0.3464
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.0026 0.0072
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0345 0.0213 0.5221
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0091 0.0049 0.0637
Treponema pallidum NADH oxidase 0.0047 0.002 0.2786
Brugia malayi Glycosyl hydrolases family 31 protein 0.0019 0.0002 0.0012
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.002 0.0054
Entamoeba histolytica hypothetical protein 0.0232 0.014 0.1846
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0044 0.2546
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0026 0.0007 0.0058
Schistosoma mansoni neuropeptide receptor 0.0126 0.0072 0.0664
Echinococcus granulosus chromobox protein 2 0.0025 0.0006 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0029 0.0264
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0007 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Loa Loa (eye worm) hypothetical protein 0.0649 0.0411 0.3842
Brugia malayi Doublecortin family protein 0.0022 0.0004 0.0034
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0065 0.0032 0.0031
Mycobacterium leprae putative cytochrome p450 0.0044 0.0018 0.0748
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0024 0.0306
Schistosoma mansoni DNA ligase IV 0.0019 0.0002 0.0014
Trichomonas vaginalis penicillin-binding protein, putative 0.0101 0.0055 0.0711
Trichomonas vaginalis PIKK family atypical protein kinase 0.0668 0.0423 0.5638
Schistosoma mansoni biogenic amine receptor 0.0126 0.0072 0.0664
Echinococcus multilocularis zinc finger protein 0.003 0.0009 0.0008
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0047 0.002 0.1156
Trichomonas vaginalis PIKK family atypical protein kinase 0.1139 0.0729 0.9737
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0071 0.0036 0.0035
Echinococcus multilocularis G protein coupled receptor 139 0.0126 0.0072 0.0071
Schistosoma mansoni rab6-interacting 0.0022 0.0004 0.0029
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0001 0.0004
Echinococcus granulosus tar DNA binding protein 0.0223 0.0135 0.0134
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0629 0.0398 0.5304
Schistosoma mansoni opsin-like receptor 0.0126 0.0072 0.0664
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0246 0.015 0.0426
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0026 0.0007 0.0057
Giardia lamblia PHD finger protein 15 0.0048 0.002 0.0247
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Echinococcus multilocularis PHD finger protein rhinoceros 0.0048 0.002 0.002
Loa Loa (eye worm) heterochromatin protein 1 0.0089 0.0047 0.044
Brugia malayi ORL1-like opioid receptor 0.0126 0.0072 0.0925
Echinococcus multilocularis transcription factor btf3 0.0022 0.0004 0.0003
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0038 0.0354
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.031 0.0191 0.8937
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0026 0.0007 0.0073
Leishmania major cytochrome p450-like protein 0.0044 0.0018 0.0046
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0044 0.0018 0.0427
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0022 0.0004 0.0205
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0005 0.0004
Schistosoma mansoni importin-beta 2 0.0029 0.0009 0.0077
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0101 0.0055 0.1341
Brugia malayi acetyltransferase, GNAT family protein 0.0158 0.0092 0.1193
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Brugia malayi Dopamine receptor 0.0126 0.0072 0.0925
Echinococcus multilocularis neuropeptide Y receptor 0.0126 0.0072 0.0071
Brugia malayi Pre-SET motif family protein 0.0231 0.014 0.182
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0348 0.0216 0.2014
Loa Loa (eye worm) TAR-binding protein 0.0223 0.0135 0.1256
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Brugia malayi PHD-finger family protein 0.0035 0.0013 0.0151
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0011 0.0583
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0084 0.0044 0.1075
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Plasmodium vivax SET domain protein, putative 0.0035 0.0012 0.071
Loa Loa (eye worm) cytochrome P450 family protein 0.0071 0.0036 0.0329
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0044 0.0018 0.0971
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0004 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0067 0.0872
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Schistosoma mansoni growth hormone secretagogue receptor 0.0126 0.0072 0.0664
Brugia malayi hypothetical protein 0.0053 0.0024 0.0304
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0136 0.0078 0.1898
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0015 0.004
Brugia malayi glutaminase DH11.1 0.0293 0.018 0.2345
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0048 0.0021 0.0887
Schistosoma mansoni adenoreceptor 0.0126 0.0072 0.0664
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0015 0.0817
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0051 0.0023 0.0211
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0002 0.0002
Trypanosoma cruzi polo-like protein kinase, putative 0.0176 0.0104 0.0294
Mycobacterium tuberculosis Probable dehydrogenase 0.031 0.0191 0.467
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.119 0.0763 0.7129
Echinococcus granulosus neuropeptide Y receptor 0.0126 0.0072 0.0071
Brugia malayi serine/threonine-protein kinase plk-2 0.0176 0.0104 0.1347
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0101 0.0055 0.0511
Entamoeba histolytica acyl-coA synthetase, putative 0.0022 0.0004 0.0028
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.001 0.0009
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0126 0.0072 0.0071
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0047 0.002 0.1101
Echinococcus multilocularis dnaJ subfamily B 0.0316 0.0195 0.0194
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0044 0.0018 0.0427
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0126 0.0072 0.0664
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.205
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Onchocerca volvulus 0.0126 0.0072 0.4394
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.117 0.0749 1
Trypanosoma cruzi trypanothione reductase, putative 0.0136 0.0078 0.022
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0025 0.0006 0.0005
Brugia malayi putative neuropeptide receptor 0.0126 0.0072 0.0925
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0004 0.0003
Brugia malayi latrophilin 2 splice variant baaae 0.0203 0.0121 0.1578
Echinococcus multilocularis nibrin 0.0019 0.0002 0.0001
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0156 0.0091 0.009
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.049 0.0308 0.0307
Schistosoma mansoni cellular tumor antigen P53 0.0064 0.0031 0.0284
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0296 0.0182 0.2409
Giardia lamblia Kinase, PLK 0.0176 0.0104 0.136
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1663 0.1069 1
Echinococcus multilocularis 0.0044 0.0018 0.0017
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.0023 0.0062
Schistosoma mansoni microtubule-associated protein tau 0.0596 0.0377 0.3518
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0015 0.0038
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.0067 0.0181
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0108 0.1401
Echinococcus granulosus peregrin 0.0054 0.0025 0.0024
Echinococcus granulosus transportin 1 0.0029 0.0009 0.0008
Brugia malayi G-protein coupled receptor 0.0126 0.0072 0.0925
Trichomonas vaginalis D-aminoacylase, putative 0.0101 0.0055 0.0711
Schistosoma mansoni transcription factor LCR-F1 0.0068 0.0034 0.0311
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0009 0.0075
Echinococcus multilocularis jumonji domain containing protein 0.0066 0.0033 0.0032
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0645 0.0408 1
Trichomonas vaginalis helicase, putative 0.0025 0.0006 0.0048
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.025 0.0152 0.2015
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Loa Loa (eye worm) kap beta 3 protein 0.0029 0.0009 0.0077
Echinococcus multilocularis neutral alpha glucosidase AB 0.0051 0.0023 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0006 0.0331
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0283 0.0174 0.162
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0448 0.028 0.3667
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0067 0.0624
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0011 0.0114
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0015 0.0175
Echinococcus granulosus g protein coupled receptor 0.0126 0.0072 0.0071
Brugia malayi G-protein coupled receptor 0.0126 0.0072 0.0925
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0075 0.0038 0.0486
Echinococcus granulosus ecdysone induced protein 78C 0.0026 0.0007 0.0006
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0649 0.0411 0.5386
Loa Loa (eye worm) phosphofructokinase 0.0119 0.0067 0.0624
Loa Loa (eye worm) helicase 0.0025 0.0006 0.0051
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0013 0.0151
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0067 0.0872
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0047 0.002 0.0252
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0044 0.0018 0.0971
Onchocerca volvulus 0.0124 0.007 0.4298
Toxoplasma gondii NADPH-glutathione reductase 0.0047 0.002 0.0272
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0091 0.0049 0.0453
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0232 0.014 0.1304
Loa Loa (eye worm) hypothetical protein 0.0053 0.0024 0.0218
Echinococcus granulosus neuropeptides capa receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0007 0.0006
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0028 0.0344
Trichomonas vaginalis PIKK family atypical protein kinase 0.067 0.0425 0.5659
Trichomonas vaginalis PIKK family atypical protein kinase 0.0232 0.014 0.1846
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0026 0.0007 0.0006
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0015 0.0171
Leishmania major hypothetical protein, conserved 0.0101 0.0055 0.0148
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0091 0.0049 0.2812
Mycobacterium leprae conserved hypothetical protein 0.0232 0.014 0.6524
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0026 0.0007 0.0006
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0068 0.0034 0.0033
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0022 0.0058
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0046 0.0591
Plasmodium vivax glutathione reductase, putative 0.0136 0.0078 0.448
Echinococcus granulosus peptide allatostatin:somatostatin 0.0126 0.0072 0.0071
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0126 0.0072 0.0664
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0026 0.0007 0.0006
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0047 0.002 0.1139
Loa Loa (eye worm) hypothetical protein 0.0203 0.0121 0.113
Leishmania major phosphatidylinositol kinase related protein, putative 0.0246 0.015 0.0408
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0649 0.0411 0.041
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0032 0.0297
Onchocerca volvulus Serine\/threonine kinase homolog 0.0176 0.0104 0.6424
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0044 0.0018 0.0971
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Brugia malayi Tachykinin-like peptides receptor 99D 0.0126 0.0072 0.0925
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni RAR-like nuclear receptor 0.0026 0.0007 0.0057
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0024 0.0217
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0156 0.0091 0.009
Brugia malayi CXXC zinc finger family protein 0.0109 0.006 0.0778
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0044 0.0018 0.0427
Brugia malayi nuclear hormone receptor 0.0026 0.0007 0.0073
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0126 0.0072 0.0071
Mycobacterium ulcerans hypothetical protein 0.0101 0.0055 0.3052
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0126 0.0072 0.0925
Plasmodium vivax transportin, putative 0.0029 0.0009 0.0496
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0126 0.0072 0.0665
Plasmodium vivax replication factor C subunit 1, putative 0.0019 0.0002 0.0111
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0094 0.0051 0.0649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Onchocerca volvulus 0.0126 0.0072 0.4394
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Onchocerca volvulus 0.0126 0.0072 0.4394
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Trypanosoma cruzi cruzipain precursor, putative 0.0049 0.0022 0.0058
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0174 0.0495
Leishmania major phosphatidylinositol kinase, putative 0.0232 0.014 0.0381
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Schistosoma mansoni hypothetical protein 0.0024 0.0005 0.0043
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0031 0.0009 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0022 0.0004 0.0205
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0044 0.0018 0.0971
Echinococcus multilocularis fmrfamide receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis transportin 1 0.0029 0.0009 0.0008
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0006 0.005
Brugia malayi hypothetical protein 0.0022 0.0004 0.0034
Brugia malayi Latrophilin receptor protein 2 0.0094 0.0051 0.0649
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0047 0.002 0.4501
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0004 0.0028
Schistosoma mansoni hypothetical protein 0.0068 0.0034 0.0311
Brugia malayi Protein cec-1. 0.0025 0.0006 0.0063
Schistosoma mansoni biogenic amine (5HT) receptor 0.0126 0.0072 0.0664
Echinococcus multilocularis sex peptide receptor 0.0126 0.0072 0.0071
Plasmodium falciparum importin beta, putative 0.0156 0.0091 0.5213
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0232 0.014 0.1887
Schistosoma mansoni alpha-glucosidase 0.0199 0.0119 0.111
Brugia malayi CHD4 protein 0.0033 0.0011 0.0132
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0025 0.0006 0.0313
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Entamoeba histolytica hypothetical protein 0.0232 0.014 0.1846
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0044 0.0018 0.0971
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0021 0.1191
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0026 0.0007 0.0058
Echinococcus granulosus beta LACTamase domain containing family member 0.0101 0.0055 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0014 0.0166
Entamoeba histolytica hypothetical protein 0.0025 0.0006 0.0051
Entamoeba histolytica HEAT repeat domain containing protein 0.0029 0.0009 0.009
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0024 0.0066
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0025 0.0006 0.0338
Brugia malayi GnHR receptor homolog 0.0126 0.0072 0.0925
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0804 0.0512 0.0511
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.8378
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0026 0.0316
Plasmodium vivax hypothetical protein, conserved 0.0232 0.014 0.8057
Brugia malayi Intermediate filament tail domain containing protein 0.0135 0.0077 0.0997
Brugia malayi chromobox protein homolog 3 0.0055 0.0026 0.0322
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0026 0.0007 0.029
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0101 0.0055 0.071
Leishmania major cytochrome p450-like protein 0.0044 0.0018 0.0046
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0004 0.004
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0084 0.0044 0.0567
Trypanosoma cruzi hypothetical protein, conserved 0.0101 0.0055 0.0155
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0044 0.0018 0.0427
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0011 0.2304
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0004 0.0008
Schistosoma mansoni hypothetical protein 0.0048 0.002 0.0187
Brugia malayi Steroid receptor seven-up type 2 0.0026 0.0007 0.0073
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0185 0.011 0.1024
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0283 0.0174 0.2342
Echinococcus multilocularis GPCR, family 2 0.0094 0.0051 0.005
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0044 0.0018 0.0427
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0026 0.0007 0.0057
Plasmodium falciparum thioredoxin reductase 0.0047 0.002 0.1139
Echinococcus multilocularis Chromo domain 0.0025 0.0006 0.0005
Entamoeba histolytica hypothetical protein 0.0068 0.0034 0.0424
Brugia malayi glutathione reductase 0.0136 0.0078 0.1008
Echinococcus multilocularis orexin receptor type 2 0.0126 0.0072 0.0071
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0044 0.0018 0.0427
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0044 0.0018 0.0046
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0004 0.0031
Echinococcus granulosus neuropeptide receptor 0.0126 0.0072 0.0071
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.0026 0.0069
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Onchocerca volvulus 0.0135 0.0077 0.4738
Brugia malayi intermediate filament protein 0.0135 0.0077 0.0997
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Toxoplasma gondii thioredoxin reductase 0.0136 0.0078 0.105
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0015 0.2003
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0003 0.0163
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0297 0.0182 0.2378
Schistosoma mansoni cpg binding protein 0.0117 0.0066 0.0609
Plasmodium falciparum replication factor C subunit 1, putative 0.0019 0.0002 0.0092
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0126 0.0072 0.0664
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0283 0.0174 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0015 0.0175
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0001 0.0069
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0004 0.0087
Echinococcus multilocularis lysosomal alpha glucosidase 0.0232 0.014 0.0139
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0027 0.0026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0108 0.0107
Trypanosoma cruzi transcription factor btf3, putative 0.0022 0.0004 0.0008
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0126 0.0072 0.0664
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0071 0.0036 0.1962
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0033 0.0011 0.01
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0072 0.0036 0.0336
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0051 0.0023 0.0281
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0565 0.0356 0.4741
Echinococcus multilocularis allatostatin A receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) TYRA-2 protein 0.0126 0.0072 0.0665
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0007 0.0073
Mycobacterium ulcerans glutaminase 0.0293 0.018 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.117 0.0749 0.2147
Schistosoma mansoni ap endonuclease 0.0039 0.0015 0.0136
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0025 0.0006 0.0606
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0004 0.0003
Brugia malayi Cytochrome P450 family protein 0.0044 0.0018 0.022
Trypanosoma brucei cytochrome P450, putative 0.0071 0.0036 0.0459
Brugia malayi TAR-binding protein 0.0223 0.0135 0.1755
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0001 0.0008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0007 0.0006
Brugia malayi neuropeptide F receptor 0.0126 0.0072 0.0925
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0232 0.014 0.1304
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0004 0.0003
Plasmodium falciparum sentrin-specific protease 1 0.005 0.0022 0.1243
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.0067 0.1635
Loa Loa (eye worm) latrophilin receptor protein 2 0.0094 0.0051 0.0468
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0044 0.0018 0.0971
Echinococcus multilocularis RUN 0.0022 0.0004 0.0003
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.119 0.0763 0.0762
Echinococcus granulosus tm gpcr rhodopsin 0.0126 0.0072 0.0071
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0051 0.0023 0.0281
Echinococcus granulosus mixed lineage leukemia protein mll 0.0028 0.0008 0.0007
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0004 0.0204
Onchocerca volvulus Protein ultraspiracle homolog 0.0026 0.0007 0.029
Schistosoma mansoni Smad4 0.0018 0.0001 0.0005
Brugia malayi 6-phosphofructokinase 0.0119 0.0067 0.0868
Loa Loa (eye worm) MH2 domain-containing protein 0.026 0.0158 0.1477
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 1.5416 1 1
Loa Loa (eye worm) hypothetical protein 0.0182 0.0108 0.1002
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0117 0.0065 0.0184
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0126 0.0072 0.0664
Trypanosoma brucei glucosidase, putative 0.0051 0.0023 0.029
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0099 0.0054 0.0498
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0108 0.0107
Plasmodium falciparum phd finger protein, putative 0.0048 0.002 0.1156
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0065 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Echinococcus granulosus g protein coupled receptor 0.0126 0.0072 0.0071
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0015 0.0863
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0006 0.005
Leishmania major glycosyl hydrolase-like protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0232 0.014 0.1305
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0025 0.0006 0.0187
Mycobacterium leprae Conserved hypothetical protein 0.0044 0.0018 0.0748
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0047 0.002 0.0252
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0004 0.0197
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.0216 0.2861
Echinococcus granulosus lysosomal alpha glucosidase 0.0232 0.014 0.0139
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0004 0.0223
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0283 0.0174 0.2297
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0033 0.0011 0.001
Schistosoma mansoni smad1 5 8 and 0.0018 0.0001 0.0005
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0348 0.0216 0.2868
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0126 0.0072 0.0925
Brugia malayi RNA, U transporter 1 0.0443 0.0277 0.3627
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Loa Loa (eye worm) hypothetical protein 0.0082 0.0043 0.0394
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0044 0.0018 0.0047
Loa Loa (eye worm) RNA binding protein 0.0223 0.0135 0.1256
Echinococcus multilocularis peregrin 0.0054 0.0025 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.5047 0.3267 0.3267
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.0026 0.0025
Echinococcus granulosus peptidase Clp S14 family 0.0048 0.0021 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0004 0.0028
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0026 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.053 0.0334 0.444
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0011 0.0114
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0004 0.003
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0026 0.0007 0.0058
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.117 0.0749 0.9824
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0044 0.0018 0.0971
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.0026 0.0334
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.0026 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Loa Loa (eye worm) glutathione reductase 0.0136 0.0078 0.0724
Trypanosoma brucei importin beta-1 subunit, putative 0.0156 0.0091 0.1196
Schistosoma mansoni smad1 5 8 and 0.0018 0.0001 0.0005
Brugia malayi sulfakinin receptor protein 0.0126 0.0072 0.0925
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0004 0.0092
Echinococcus multilocularis tar DNA binding protein 0.0223 0.0135 0.0134
Echinococcus multilocularis chromobox protein 1 0.0089 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0034
Echinococcus granulosus snurportin 1 0.1663 0.1069 0.1069
Echinococcus granulosus biogenic amine 5HT receptor 0.0126 0.0072 0.0071
Plasmodium falciparum basic transcription factor 3b, putative 0.0022 0.0004 0.0213
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0067 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Loa Loa (eye worm) jmjC domain-containing protein 0.0098 0.0053 0.0495
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0006 0.0051
Schistosoma mansoni coup transcription factor 0.0026 0.0007 0.0057
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0001 0.0018
Leishmania major trypanothione reductase 0.0136 0.0078 0.0211
Onchocerca volvulus 0.0126 0.0072 0.4394
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0283 0.0174 0.2297
Onchocerca volvulus 0.0126 0.0072 0.4394
Schistosoma mansoni smad 0.0018 0.0001 0.0005
Leishmania major alpha glucosidase II subunit, putative 0.0051 0.0023 0.006
Brugia malayi Bromodomain containing protein 0.0043 0.0017 0.0215
Echinococcus multilocularis G-protein coupled receptor, putative 0.0126 0.0072 0.0071
Echinococcus multilocularis sentrin specific protease 1 0.005 0.0022 0.0021
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0015 0.0014
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0011 0.0601
Mycobacterium ulcerans hypothetical protein 0.0022 0.0004 0.0197
Echinococcus multilocularis lamin 0.0135 0.0077 0.0076
Echinococcus granulosus neuropeptide s receptor 0.0423 0.0264 0.0263
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0011 0.0114
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.119 0.0763 0.2185
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0026 0.0325
Echinococcus multilocularis neuropeptide Y receptor 0.0126 0.0072 0.0071
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0026 0.0007 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0649 0.0411 0.5477
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0009 0.0008
Leishmania major GTP-binding protein, putative 0.0091 0.0049 0.0131
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0126 0.0072 0.0664
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0004 0.0003
Trypanosoma brucei hypothetical protein, conserved 0.0101 0.0055 0.072
Schistosoma mansoni alpha-1 adrenergic receptor 0.0126 0.0072 0.0664
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Onchocerca volvulus 0.006 0.0029 0.1687
Echinococcus multilocularis tumor protein p63 0.0434 0.0272 0.0271
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Schistosoma mansoni polycystin 1-related 0.0022 0.0004 0.0029
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0011 0.0142
Leishmania major cathepsin L-like protease 0.0049 0.0022 0.0056
Schistosoma mansoni chromobox protein 0.0089 0.0047 0.0439
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0015 0.0175
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0232 0.014 0.0139
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.005 0.0022 0.0267
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0026 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0009 0.0098
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0091 0.0049 0.0137
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0061 0.0029 0.0028
Brugia malayi Heterochromatin protein 1 0.0089 0.0047 0.0609
Echinococcus granulosus RUN 0.0022 0.0004 0.0003
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0722 0.0458 0.6179
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0126 0.0072 0.0664
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0091 0.0049 0.0628
Brugia malayi SET domain containing protein 0.0029 0.0008 0.0093
Mycobacterium ulcerans hypothetical protein 0.0022 0.0004 0.0205
Schistosoma mansoni cpg binding protein 0.0109 0.006 0.0559
Trypanosoma cruzi target of rapamycin kinase 3 0.116 0.0743 0.2129
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma brucei glycosyl hydrolase-like protein 0.0019 0.0002 0.001
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0035 0.0012 0.0144
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0067 0.0624
Echinococcus multilocularis lysosomal alpha glucosidase 0.0232 0.014 0.0139
Loa Loa (eye worm) phosphatidylinositol kinase 0.0232 0.014 0.1305
Loa Loa (eye worm) hypothetical protein 0.0064 0.0031 0.0284
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0283 0.0174 0.2342
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0004 0.0186
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0047 0.002 0.5162
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0015 0.004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0007 0.0073
Loa Loa (eye worm) hypothetical protein 0.0062 0.003 0.0278
Echinococcus multilocularis thyroid hormone receptor alpha 0.0026 0.0007 0.0006
Loa Loa (eye worm) cytochrome P450 family protein 0.0121 0.0068 0.0631
Brugia malayi putative neuropeptide receptor NPR1 0.0126 0.0072 0.0925
Giardia lamblia GTOR 0.117 0.0749 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0126 0.0072 0.0071
Schistosoma mansoni hypothetical protein 0.0022 0.0004 0.0029
Brugia malayi Pre-SET motif family protein 0.0035 0.0012 0.0149
Schistosoma mansoni hypothetical protein 0.0126 0.0072 0.0664
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0001 0.0018
Schistosoma mansoni biogenic amine receptor 0.0126 0.0072 0.0664
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0007 0.0073
Schistosoma mansoni neuropeptide receptor 0.0126 0.0072 0.0664
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0094 0.0051 0.005
Schistosoma mansoni zinc finger protein 0.003 0.0009 0.008
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0135 0.0077 0.0716
Schistosoma mansoni importin beta-1 0.0156 0.0091 0.0844
Echinococcus multilocularis chromobox protein 1 0.0089 0.0047 0.0047
Loa Loa (eye worm) histone methyltransferase 0.0035 0.0012 0.011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Entamoeba histolytica hypothetical protein 0.0565 0.0356 0.4741
Loa Loa (eye worm) hypothetical protein 0.0297 0.0182 0.17
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis maltase-glucoamylase, putative 0.0051 0.0023 0.0281
Entamoeba histolytica hypothetical protein 0.0126 0.0072 0.0931
Mycobacterium tuberculosis Probable lipase LipD 0.0101 0.0055 0.1341
Brugia malayi MH2 domain containing protein 0.026 0.0158 0.2065
Loa Loa (eye worm) hypothetical protein 0.0178 0.0105 0.0981
Brugia malayi Importin beta-1 subunit 0.0156 0.0091 0.1177
Brugia malayi Melibiase family protein 0.0075 0.0038 0.0489
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.005 0.0022 0.0266
Brugia malayi Pax transcription activation domain interacting protein 0.0019 0.0002 0.0013
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0629 0.0398 0.5217
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0664 0.0421 0.5512
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0004 0.0038
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0101 0.0055 0.1341
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0232 0.014 0.1846
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0004 0.009
Brugia malayi DKFZp564C0469 protein 0.0019 0.0002 0.0013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0108 0.1003
Schistosoma mansoni glutaminase 0.0293 0.018 0.1676
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0051 0.0023 0.0281
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0001 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0012 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0668 0.0423 0.5638
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0073 0.0037 0.1662
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.115 0.0737 0.9832
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) hypothetical protein 0.0722 0.0458 0.4282
Echinococcus granulosus sentrin specific protease 1 0.005 0.0022 0.0021
Echinococcus granulosus tm gpcr rhodopsin 0.5047 0.3267 0.3267
Echinococcus multilocularis fmrfamide receptor 0.0126 0.0072 0.0071
Echinococcus granulosus lamin 0.0135 0.0077 0.0076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0006 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Brugia malayi Dopamine receptor protein 2 0.0126 0.0072 0.0925
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0047 0.002 0.1156
Leishmania major importin beta-1 subunit, putative 0.0126 0.0072 0.0193
Entamoeba histolytica serine/threonine protein kinase, putative 0.0176 0.0104 0.136
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0126 0.0072 0.0931
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0063 0.0582
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0232 0.014 0.8054
Loa Loa (eye worm) hypothetical protein 0.049 0.0308 0.2876
Onchocerca volvulus 0.0232 0.014 0.872
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0232 0.014 0.1887
Echinococcus multilocularis cpg binding protein 0.0117 0.0066 0.0065
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0108 0.1003
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0044 0.0018 0.0427
Schistosoma mansoni lamin 0.0135 0.0077 0.0715
Trichomonas vaginalis penicillin-binding protein, putative 0.0101 0.0055 0.0711
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0731 0.0464 0.6191
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Trypanosoma cruzi importin beta-1 subunit, putative 0.0126 0.0072 0.0202
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0067 0.0624
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0002 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0007 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0007 0.0073
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0007 0.0073
Echinococcus multilocularis translational activator gcn1 0.0029 0.0009 0.0008
Giardia lamblia Hypothetical protein 0.0232 0.014 0.1846
Echinococcus multilocularis Chromobox protein 3 0.0025 0.0006 0.0005
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0232 0.014 0.0398
Trichomonas vaginalis Heterochromatin protein, putative 0.0025 0.0006 0.0051
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0006 0.0079
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0348 0.0216 0.2819
Brugia malayi ecdysteroid receptor 0.0026 0.0007 0.0073
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.005 0.0022 0.0297
Loa Loa (eye worm) intermediate filament protein 0.0135 0.0077 0.0716
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0003 0.0026
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0017 0.0942
Loa Loa (eye worm) hypothetical protein 0.0055 0.0026 0.0235
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0044 0.0018 0.0971
Schistosoma mansoni chromobox protein 0.0089 0.0047 0.0439
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0022 0.0004 0.0205
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0649 0.0411 0.041
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.117 0.0749 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Trichomonas vaginalis D-aminoacylase, putative 0.0101 0.0055 0.0711
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0067 0.0872
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.0026 0.0325
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0044 0.0018 0.0971
Brugia malayi hypothetical protein 0.0019 0.0002 0.0013
Mycobacterium tuberculosis Probable reductase 0.031 0.0191 0.467
Plasmodium vivax hypothetical protein, conserved 0.0101 0.0055 0.3171
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Mycobacterium tuberculosis Probable oxidoreductase 0.0345 0.0213 0.5221
Loa Loa (eye worm) CYP4Cod1 0.0071 0.0036 0.0329
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0028 0.0008 0.0007
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0126 0.0072 0.0071
Brugia malayi beta-lactamase family protein 0.0101 0.0055 0.071
Brugia malayi Thioredoxin reductase 0.0136 0.0078 0.1008
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0232 0.014 0.1887
Echinococcus granulosus allatostatin A receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0126 0.0072 0.0665
Schistosoma mansoni topbp1 0.0019 0.0002 0.0014
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0084 0.0044 0.1999
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0174 0.0495
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0024 0.1372
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Echinococcus granulosus neuropeptide receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis glutaminase, putative 0.0293 0.018 0.2377
Onchocerca volvulus Huntingtin homolog 0.0178 0.0105 0.6531
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Trypanosoma cruzi polo-like protein kinase, putative 0.0176 0.0104 0.0294
Plasmodium vivax heterochromatin protein 1, putative 0.0025 0.0006 0.0331
Trichomonas vaginalis ran, putative 0.0091 0.0049 0.0628
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0001 0.0004
Echinococcus multilocularis importin 5 0.0029 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0418 0.0261 0.3464
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Onchocerca volvulus 0.0022 0.0004 0.0132
Onchocerca volvulus 0.0126 0.0072 0.4394
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0008 0.0007
Echinococcus granulosus serine protein kinase ATM 0.0664 0.0421 0.042
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0126 0.0072 0.0071
Entamoeba histolytica hypothetical protein 0.0232 0.014 0.1846
Trichomonas vaginalis conserved hypothetical protein 0.049 0.0308 0.4094
Schistosoma mansoni hypothetical protein 0.049 0.0308 0.2875
Leishmania major hypothetical protein, conserved 0.0029 0.0009 0.002
Loa Loa (eye worm) ICD-1 protein 0.0022 0.0004 0.0034
Schistosoma mansoni hypothetical protein 0.0126 0.0072 0.0664
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Brugia malayi phosphofructokinase 0.0119 0.0067 0.0868
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.031 0.0191 0.467
Loa Loa (eye worm) beta-lactamase 0.0101 0.0055 0.0512
Brugia malayi topoisomerase 0.0019 0.0002 0.0013
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0007 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0026 0.0007 0.0073
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0101 0.0055 0.0511
Onchocerca volvulus 0.0126 0.0072 0.4394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0232 0.014 0.1846
Brugia malayi hypothetical protein 0.0178 0.0105 0.1369
Onchocerca volvulus 0.0126 0.0072 0.4394
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0016 0.0015
Schistosoma mansoni intermediate filament proteins 0.0135 0.0077 0.0715
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0649 0.0411 0.1177
Brugia malayi RE15519p 0.0126 0.0072 0.0925
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.0026 0.0025
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0126 0.0072 0.0664
Mycobacterium tuberculosis Conserved protein 0.0101 0.0055 0.1341
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0126 0.0072 0.0925
Schistosoma mansoni ran 0.0091 0.0049 0.0453
Trichomonas vaginalis PIKK family atypical protein kinase 0.1139 0.0729 0.9737
Echinococcus granulosus neuropeptides capa receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0126 0.0072 0.0071
Loa Loa (eye worm) CXXC zinc finger family protein 0.0109 0.006 0.056
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0019 0.0002 0.0028
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0044 0.0018 0.0427
Schistosoma mansoni hypothetical protein 0.0094 0.0051 0.0468
Schistosoma mansoni cpg binding protein 0.0117 0.0066 0.0609
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.005 0.0022 0.0266
Echinococcus granulosus 7tm_1 domain containing protein 0.0126 0.0072 0.0071
Entamoeba histolytica hypothetical protein 0.0068 0.0034 0.0424
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0104 0.0965
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.117 0.0749 1
Schistosoma mansoni rab6-interacting 0.0022 0.0004 0.0029
Echinococcus granulosus replication factor c subunit 1 0.0019 0.0002 0.0001
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.0216 0.2861
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0015 0.3713
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0283 0.0174 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Trichomonas vaginalis D-aminoacylase, putative 0.0101 0.0055 0.0711
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0283 0.0174 0.0173
Trypanosoma brucei target of rapamycin kinase 3, putative 0.116 0.0743 0.9919
Echinococcus multilocularis replication factor c subunit 1 0.0019 0.0002 0.0001
Plasmodium falciparum transportin 0.0029 0.0009 0.0478
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0017 0.0197
Schistosoma mansoni peptidase Clp (S14 family) 0.0073 0.0037 0.0343
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0013 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Schistosoma mansoni myosin xvIII 0.0126 0.0072 0.0664
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.005 0.0022 0.0201
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0026 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Brugia malayi Associated with TFs and helicases family protein 0.0025 0.0006 0.0063
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Echinococcus multilocularis snurportin 1 0.1663 0.1069 0.1069
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0015 0.0175
Echinococcus granulosus zinc finger protein 0.003 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0743 0.0472 0.6288
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0174 0.2305
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0629 0.0398 0.5304
Brugia malayi hypothetical protein 0.0034 0.0012 0.0143
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0046 0.0591
Trichomonas vaginalis PIKK family atypical protein kinase 0.1139 0.0729 0.9737
Trypanosoma brucei polo-like protein kinase 0.0176 0.0104 0.1368
Echinococcus granulosus G protein coupled receptor 139 0.0126 0.0072 0.0071
Onchocerca volvulus Neuropeptide F receptor homolog 0.0126 0.0072 0.4394
Trypanosoma brucei trypanothione reductase 0.0136 0.0078 0.1024
Loa Loa (eye worm) hypothetical protein 0.0072 0.0036 0.0337
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0015 0.0184
Schistosoma mansoni ap endonuclease 0.0039 0.0015 0.0136
Toxoplasma gondii NAC domain-containing protein 0.0022 0.0004 0.0056
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0026 0.0007 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0044 0.0018 0.0427
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Trypanosoma cruzi FHA domain containing protein, putative 0.0019 0.0002 0.0002
Brugia malayi cytoplasmic intermediate filament protein 0.0072 0.0036 0.0464
Loa Loa (eye worm) phosphatidylinositol 3 0.0117 0.0065 0.0608
Leishmania major basic transcription factor 3a, putative 0.0022 0.0004 0.0008
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0024 0.1372
Echinococcus multilocularis 0.0232 0.014 0.0139
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0664 0.0421 0.3932
Echinococcus multilocularis serotonin receptor 0.0126 0.0072 0.0071
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.049 0.0308 0.0307
Leishmania major phosphatidylinositol 3-related kinase, putative 0.115 0.0737 0.2023
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0004 0.0205
Loa Loa (eye worm) G-protein coupled receptor 0.0126 0.0072 0.0665
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Echinococcus granulosus dro:myosuppressin receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Leishmania major phosphatidylinositol 3-kinase, putative 0.1139 0.0729 0.2004
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0101 0.0055 0.0512
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0026 0.0007 0.0058
Brugia malayi neuropeptide F receptor 0.0126 0.0072 0.0925
Echinococcus granulosus cpg binding protein 0.0117 0.0066 0.0065
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0073 0.0037 0.0036
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0448 0.028 0.0279
Plasmodium falciparum glutathione reductase 0.0136 0.0078 0.447
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0044 0.0018 0.0427
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0004 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0026 0.0007 0.0073
Brugia malayi Melatonin receptor type 1A 0.0126 0.0072 0.0925
Echinococcus granulosus Chromo domain 0.0025 0.0006 0.0005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0232 0.014 0.342
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0019 0.0002 0.0013
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0021 0.0281
Chlamydia trachomatis endonuclease IV 0.0084 0.0044 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0047 0.002 0.0243
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0019 0.0169
Onchocerca volvulus 0.0101 0.0055 0.3358
Mycobacterium ulcerans beta-lactamase 0.0101 0.0055 0.3052
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0126 0.0072 0.0071
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0073 0.0037 0.0502
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.014 0.1302
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0067 0.0881
Schistosoma mansoni hypothetical protein 0.0094 0.0051 0.0468
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0044 0.0018 0.0971
Brugia malayi RNA binding protein 0.0223 0.0135 0.1755
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0044 0.0018 0.0971
Echinococcus granulosus neuropeptide FF receptor 2 0.0126 0.0072 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Trichomonas vaginalis glutathione reductase, putative 0.0047 0.002 0.0243
Brugia malayi Cytochrome P450 family protein 0.0071 0.0036 0.0453
Mycobacterium tuberculosis Putative ferredoxin reductase 0.031 0.0191 0.467
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0015 0.0171
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0126 0.0072 0.0071
Loa Loa (eye worm) importin-beta domain-containing protein 0.0029 0.0009 0.0077
Loa Loa (eye worm) hypothetical protein 0.0075 0.0038 0.0354
Loa Loa (eye worm) hypothetical protein 0.0094 0.0051 0.0468
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0064
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0025 0.0006 0.032
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0021 0.0251
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0051 0.0023 0.031
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0006 0.0313
Onchocerca volvulus 0.0232 0.014 0.872
Loa Loa (eye worm) hypothetical protein 0.0448 0.028 0.2618
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.031 0.0191 0.467
Loa Loa (eye worm) hypothetical protein 0.0156 0.0091 0.0845
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0001 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0722 0.0458 0.6106
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Loa Loa (eye worm) PHD-finger family protein 0.0048 0.002 0.0187
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0022 0.0004 0.009
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.0067 1
Echinococcus granulosus neutral alpha glucosidase AB 0.0051 0.0023 0.0022
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0052
Toxoplasma gondii PHD-finger domain-containing protein 0.0048 0.002 0.0276
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Brugia malayi RNA recognition motif domain containing protein 0.0223 0.0135 0.1755
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.0026 0.0355
Loa Loa (eye worm) hypothetical protein 0.0032 0.0011 0.0095
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0025 0.0006 0.0063
Mycobacterium tuberculosis Conserved protein 0.0101 0.0055 0.1341
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus multilocularis serotonin receptor 0.0126 0.0072 0.0071
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0283 0.0174 0.162
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0283 0.0174 0.0173
Echinococcus multilocularis peptidase Clp (S14 family) 0.0048 0.0021 0.002
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0044 0.0018 0.0427
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0283 0.0174 0.0474
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0176 0.0104 0.0103
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0126 0.0072 0.0664
Loa Loa (eye worm) cytochrome P450 family protein 0.0071 0.0036 0.0329
Brugia malayi M-phase phosphoprotein, mpp8 0.0124 0.007 0.0905
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0348 0.0216 0.0616
Echinococcus granulosus jumonji domain containing protein 0.0066 0.0033 0.0032
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0113 0.0063 0.0062
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0099 0.0054 0.0498
Schistosoma mansoni neuropeptide F-like receptor 0.0126 0.0072 0.0664
Toxoplasma gondii hypothetical protein 0.0025 0.0006 0.0081
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0232 0.014 0.8057
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0108 0.1003
Brugia malayi Bromodomain containing protein 0.0087 0.0046 0.0587
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0108 0.1004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Loa Loa (eye worm) hypothetical protein 0.005 0.0022 0.0201
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0012 0.0012
Mycobacterium ulcerans epimerase 0.0022 0.0004 0.0197
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0232 0.014 0.0139
Trichomonas vaginalis mercuric reductase, putative 0.0047 0.002 0.0243
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0185 0.011 0.6818
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0029 0.0009 0.0099
Leishmania major hypothetical protein, conserved 0.5614 0.3635 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0041 0.0016 0.0201
Onchocerca volvulus Bile acid receptor homolog 0.0026 0.0007 0.029
Trypanosoma brucei transcription factor BTF3, putative 0.0022 0.0004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) hypothetical protein 0.0349 0.0216 0.2016
Echinococcus granulosus somatostatin receptor 0.0126 0.0072 0.0071
Brugia malayi Calcitonin receptor-like protein seb-1 0.0297 0.0182 0.2378
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.117 0.0749 0.2058
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.0398
Echinococcus multilocularis neuropeptides capa receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) neuropeptide F receptor 0.0126 0.0072 0.0665
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0015 0.0845
Leishmania major hypothetical protein, conserved 0.0053 0.0024 0.0063
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Entamoeba histolytica hypothetical protein 0.0664 0.0421 0.5606
Echinococcus granulosus neuropeptide receptor A26 0.0423 0.0264 0.0263
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0004 0.0205
Echinococcus granulosus importin 5 0.0029 0.0009 0.0008
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0044 0.0018 0.0971
Echinococcus granulosus intermediate filament protein 0.0135 0.0077 0.0076
Onchocerca volvulus 0.0101 0.0055 0.3358
Toxoplasma gondii FATC domain-containing protein 0.0664 0.0421 0.5675
Trypanosoma cruzi major cysteine proteinase, putative 0.0039 0.0015 0.0038
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Brugia malayi jmjC domain containing protein 0.0156 0.0091 0.1177
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0232 0.014 0.1824
Schistosoma mansoni hypothetical protein 0.0094 0.0051 0.0468
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0026 0.0325
Trichomonas vaginalis set domain proteins, putative 0.0263 0.016 0.2117
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0022 0.0058
Loa Loa (eye worm) RecQ helicase 0.0024 0.0005 0.0044
Brugia malayi MAP kinase sur-1 0.0057 0.0026 0.0331
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0034
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0026 0.0072
Brugia malayi FAT domain containing protein 0.049 0.0308 0.4029
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0348 0.0216 0.2861
Brugia malayi beta-lactamase family protein 0.0101 0.0055 0.071
Mycobacterium leprae Probable lipase LipE 0.0101 0.0055 0.2512
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0006 0.0331
Echinococcus granulosus chromobox protein 1 0.0089 0.0047 0.0047
Echinococcus granulosus biogenic amine 5HT receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0014 0.0166
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Brugia malayi nuclear receptor NHR-88 0.0026 0.0007 0.0073
Leishmania major cathepsin L-like protease 0.0049 0.0022 0.0056
Echinococcus granulosus nibrin 0.0019 0.0002 0.0001
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0073 0.0037 0.2136
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0033 0.0011 0.001
Echinococcus multilocularis g-protein coupled receptor 0.0126 0.0072 0.0071
Schistosoma mansoni hypothetical protein 0.0094 0.0051 0.0468
Toxoplasma gondii cytochrome p450 superfamily protein 0.0044 0.0018 0.0241
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0348 0.0216 0.2861
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0047 0.002 0.0251
Trichomonas vaginalis PIKK family atypical protein kinase 0.066 0.0418 0.5571
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Plasmodium vivax basic transcription factor 3b, putative 0.0022 0.0004 0.0231
Echinococcus granulosus alpha 1A adrenergic receptor 0.0126 0.0072 0.0071
Schistosoma mansoni chromosome transmission fidelity factor 0.0019 0.0002 0.0014
Schistosoma mansoni transcription factor btf3 0.0022 0.0004 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.117 0.0749 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0026 0.0007 0.0006
Brugia malayi beta-lactamase 0.0101 0.0055 0.071
Toxoplasma gondii target of rapamycin (TOR), putative 0.1158 0.0742 1
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0047 0.0608
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Schistosoma mansoni hypothetical protein 0.0232 0.014 0.1304
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0008 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0126 0.0072 0.0664
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0232 0.014 0.0139
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0629 0.0398 0.5304
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Brugia malayi PHD-finger family protein 0.0024 0.0005 0.0051
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0126 0.0072 0.4394
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0004 0.0123
Onchocerca volvulus 0.0126 0.0072 0.4394
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0032 0.0031
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0126 0.0072 0.0665
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0035 0.0012 0.0011
Echinococcus granulosus transcription factor btf3 0.0022 0.0004 0.0003
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0047 0.002 0.0252
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0101 0.0055 0.0155
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Leishmania major phosphatidylinositol 3-kinase, putative 0.0283 0.0174 0.0474
Echinococcus granulosus orexin receptor type 2 0.0126 0.0072 0.0071
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0047 0.002 0.5162
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0004 0.0205
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.005 0.0022 0.0201
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0099 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trichomonas vaginalis PIKK family atypical protein kinase 0.1151 0.0737 0.9838
Echinococcus granulosus cytochrome P450 2K1 0.0044 0.0018 0.0017
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0047 0.002 0.1101
Echinococcus granulosus GTP binding nuclear protein Ran 0.0091 0.0049 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0026 0.0316
Echinococcus granulosus thioredoxin glutathione reductase 0.0136 0.0078 0.0077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus granulosus translational activator gcn1 0.0029 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0433 0.027 0.0773
Brugia malayi Serotonin receptor 0.0126 0.0072 0.0925
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0101 0.0055 0.3052
Loa Loa (eye worm) hypothetical protein 0.0073 0.0037 0.0344
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0026 0.0007 0.0057
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0007 0.0073
Brugia malayi Serotonin receptor 0.0126 0.0072 0.0925
Schistosoma mansoni jumonji domain containing protein 0.0124 0.007 0.0649
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0047 0.002 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus multilocularis ecdysone induced protein 78C 0.0026 0.0007 0.0006
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0026 0.0007 0.0057
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0044 0.2531
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.5396
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0067 0.0872
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0126 0.0072 0.0665
Schistosoma mansoni alpha-glucosidase 0.0199 0.0119 0.111
Loa Loa (eye worm) hypothetical protein 0.0135 0.0077 0.0716
Trichomonas vaginalis PIKK family atypical protein kinase 0.1139 0.0729 0.9737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0664 0.0421 0.5606
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0021 0.0251
Schistosoma mansoni lipoxygenase 0.0022 0.0004 0.0029
Echinococcus granulosus histone acetyltransferase KAT2B 0.0151 0.0088 0.0087
Loa Loa (eye worm) melatonin receptor type 1A 0.0126 0.0072 0.0665
Loa Loa (eye worm) hypothetical protein 0.0124 0.007 0.0651
Schistosoma mansoni hypothetical protein 0.0044 0.0018 0.0162
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0005 0.0053
Onchocerca volvulus Alhambra homolog 0.0048 0.002 0.1165
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0067 0.0624
Entamoeba histolytica hypothetical protein 0.0068 0.0034 0.0424
Onchocerca volvulus 0.0034 0.0011 0.0595
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Echinococcus multilocularis g protein coupled receptor 0.0126 0.0072 0.0071
Schistosoma mansoni steroid hormone receptor ad4bp 0.0026 0.0007 0.0057
Onchocerca volvulus Huntingtin homolog 0.0178 0.0105 0.6531
Loa Loa (eye worm) hypothetical protein 0.0062 0.003 0.0278
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0004 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0026 0.0007 0.0073
Brugia malayi Probable ClpP-like protease 0.0073 0.0037 0.0474
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0002 0.0013
Onchocerca volvulus 0.0109 0.006 0.3684
Brugia malayi AKH receptor 0.0126 0.0072 0.0925
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0348 0.0216 0.2861
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0042
Loa Loa (eye worm) hypothetical protein 0.0045 0.0019 0.0174
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0283 0.0174 0.2266
Loa Loa (eye worm) hypothetical protein 0.0101 0.0055 0.0512
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0047 0.002 0.0052
Brugia malayi photoreceptor-specific nuclear receptor 0.0026 0.0007 0.0073
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0005 0.0042
Echinococcus multilocularis neuropeptide s receptor 0.0423 0.0264 0.0263
Schistosoma mansoni hypothetical protein 0.0025 0.0006 0.005
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3846 0.2487 0.2487
Loa Loa (eye worm) hypothetical protein 0.0121 0.0068 0.0631
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0108 0.0107
Plasmodium falciparum heterochromatin protein 1 0.0025 0.0006 0.0313
Mycobacterium leprae conserved hypothetical protein 0.0101 0.0055 0.2512
Brugia malayi Valyl-tRNA synthetase 0.0025 0.0006 0.0063
Entamoeba histolytica Ran family GTPase 0.0091 0.0049 0.0628
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0736 0.9818
Toxoplasma gondii PHD-finger domain-containing protein 0.0048 0.002 0.0276
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0047 0.002 0.0019
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0664 0.0421 0.561
Schistosoma mansoni hypothetical protein 0.0021 0.0003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0 0.0019
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0629 0.0398 0.114
Trichomonas vaginalis PIKK family atypical protein kinase 0.117 0.0749 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0024 0.0005 0.0004
Mycobacterium tuberculosis Probable esterase LipL 0.0101 0.0055 0.1341
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0009 0.0118
Loa Loa (eye worm) hypothetical protein 0.0132 0.0075 0.0701
Schistosoma mansoni biogenic amine receptor 0.0126 0.0072 0.0664
Schistosoma mansoni opsin-like receptor 0.0126 0.0072 0.0664
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.0024 0.0023
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0032 0.0298
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0126 0.0072 0.0071
Echinococcus granulosus g-protein coupled receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0126 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni topbp1 0.0019 0.0002 0.0014
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0091 0.0049 0.066
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0045 0.0019 0.005
Echinococcus granulosus sex peptide receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0126 0.0072 0.0071
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0047 0.0608
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0345 0.0213 0.5221
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0044 0.0018 0.0971
Onchocerca volvulus 0.0126 0.0072 0.4394
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0011 0.2304
Schistosoma mansoni bromodomain containing protein 0.0075 0.0038 0.0351
Trichomonas vaginalis hypothetical protein 0.0029 0.0009 0.009
Onchocerca volvulus 0.0126 0.0072 0.4394
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0024 0.1389
Trypanosoma cruzi cytochrome P450, putative 0.0071 0.0036 0.0098
Schistosoma mansoni retinoic acid receptor RXR 0.0026 0.0007 0.0057
Schistosoma mansoni lamin 0.0135 0.0077 0.0715
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.119 0.0763 0.2185
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0067 0.0872
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0004 0.0098
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0232 0.014 0.1304
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0009 0.0118
Schistosoma mansoni loxhd1 0.0022 0.0004 0.0029
Echinococcus granulosus microtubule associated protein 2 0.0596 0.0377 0.0376
Loa Loa (eye worm) hypothetical protein 0.0124 0.007 0.0651
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0629 0.0398 0.5304
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0026 0.0007 0.0073
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Plasmodium vivax importin-beta 2, putative 0.0156 0.0091 0.5222
Trichomonas vaginalis PIKK family atypical protein kinase 0.117 0.0749 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0016 0.0015
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0126 0.0072 0.0931
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0011 0.0583
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0004 0.0003
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0038 0.0354
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.0067 0.0066
Trypanosoma cruzi transcription factor btf3, putative 0.0022 0.0004 0.0008
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.066 0.0418 0.5571
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0126 0.0072 0.0071
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0126 0.0072 0.0664
Entamoeba histolytica hypothetical protein 0.0068 0.0034 0.0424
Echinococcus granulosus bloom syndrome protein 0.0024 0.0005 0.0004
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0283 0.0174 0.2297
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0026 0.0241
Onchocerca volvulus 0.0064 0.0031 0.1823
Schistosoma mansoni smad1 5 8 and 0.0018 0.0001 0.0005
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0055 0.0026 0.149
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0232 0.014 0.1824
Mycobacterium ulcerans lipase LipD 0.0101 0.0055 0.3052
Plasmodium falciparum glutathione reductase 0.0047 0.002 0.1139
Echinococcus granulosus importin subunit beta 1 0.0156 0.0091 0.009
Onchocerca volvulus 0.0022 0.0004 0.0103
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0044 0.0018 0.0971
Brugia malayi hypothetical protein 0.0019 0.0002 0.0013
Onchocerca volvulus 0.0101 0.0055 0.3358
Brugia malayi beta-NAC-like protein 0.0022 0.0004 0.004
Brugia malayi Cytochrome P450 family protein 0.0121 0.0068 0.0878
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0158 0.0092 0.0091
Leishmania major cathepsin L-like protease 0.0049 0.0022 0.0056
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.1854
Brugia malayi Cytochrome P450 family protein 0.0071 0.0036 0.0453
Loa Loa (eye worm) G-protein coupled receptor 0.0126 0.0072 0.0665
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0048 0.0021 0.0499
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0044 0.0018 0.0427
Loa Loa (eye worm) glutaminase 2 0.0293 0.018 0.1676
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0061 0.0029 0.0028
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0004 0.004
Schistosoma mansoni alpha glucosidase 0.0051 0.0023 0.021
Echinococcus multilocularis FTZ F1 alpha 0.0026 0.0007 0.0006
Trypanosoma cruzi cytochrome P450, putative 0.0071 0.0036 0.0098
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0232 0.014 0.1306
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0052
Echinococcus multilocularis dro:myosuppressin receptor 0.0126 0.0072 0.0071
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0091 0.0049 0.2799
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0345 0.0213 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Plasmodium vivax thioredoxin reductase, putative 0.0136 0.0078 0.448
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Echinococcus multilocularis g protein coupled receptor 0.0126 0.0072 0.0071
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0073 0.0037 0.205
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.0067 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0232 0.014 0.1308
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0009 0.0098
Brugia malayi 6-phosphofructokinase 0.0119 0.0067 0.0868
Echinococcus granulosus lamin dm0 0.0135 0.0077 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.053 0.0334 0.444
Onchocerca volvulus 0.0126 0.0072 0.4394
Brugia malayi Dopamine receptor protein 1 0.0126 0.0072 0.0925
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0126 0.0072 0.0071
Entamoeba histolytica hypothetical protein 0.0025 0.0006 0.0051
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.0026 0.0072
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0113 0.0063 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0051
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0044 0.0018 0.0971
Schistosoma mansoni hypothetical protein 0.1663 0.1069 1
Schistosoma mansoni neuropeptide F-like receptor 0.0126 0.0072 0.0664
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0465 0.0292 0.3877
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0175 0.0103 0.1339
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Mycobacterium tuberculosis Probable hydrolase 0.0101 0.0055 0.1341
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0126 0.0072 0.0071
Echinococcus multilocularis neuropeptides capa receptor 0.0126 0.0072 0.0071
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0126 0.0072 0.0664
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0108 0.0107
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0126 0.0072 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0146 0.1927
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Loa Loa (eye worm) hypothetical protein 0.0034 0.0011 0.0103
Trichomonas vaginalis hypothetical protein 0.0025 0.0006 0.0051
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0047 0.002 0.1139
Onchocerca volvulus 0.0126 0.0072 0.4394
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0024 0.0066
Brugia malayi kap beta 3 protein 0.0029 0.0009 0.01
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0026 0.0007 0.0006
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0047 0.002 0.0484
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0047 0.002 0.1101
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0041 0.0016 0.0149
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Entamoeba histolytica hypothetical protein 0.0025 0.0006 0.0051
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0021 0.0281
Brugia malayi PHD-finger family protein 0.0048 0.002 0.0254
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0297 0.0182 0.17
Toxoplasma gondii endonuclease IV APN 0.0084 0.0044 0.0597
Loa Loa (eye worm) phosphatidylinositol 3 0.0232 0.014 0.1305
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0006 0.005
Echinococcus granulosus g protein coupled receptor 0.0126 0.0072 0.0071
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0383 0.0238 0.3161
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0006 0.0051
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0073 0.0037 0.0036
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0067 0.0872
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Brugia malayi F/Y-rich N-terminus family protein 0.0052 0.0023 0.0292
Loa Loa (eye worm) thioredoxin reductase 0.0136 0.0078 0.0724
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0024 0.0327
Schistosoma mansoni cytochrome P450 0.0044 0.0018 0.0162
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0094 0.0051 0.005
Brugia malayi hypothetical protein 0.0124 0.007 0.0905
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0044 0.0018 0.0427
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.031 0.0191 0.467
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0011 0.0142
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Loa Loa (eye worm) hypothetical protein 0.0178 0.0105 0.0981
Schistosoma mansoni neuropeptide f receptor 76f 0.0126 0.0072 0.0664
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.0023 0.0062
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0044 0.0018 0.0971
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0019 0.0002 0.0002
Schistosoma mansoni chromobox protein 0.0025 0.0006 0.005
Echinococcus granulosus GPCR family 2 0.0094 0.0051 0.005
Echinococcus granulosus fmrfamide receptor 0.0126 0.0072 0.0071
Echinococcus multilocularis neuropeptide receptor 0.0126 0.0072 0.0071
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Leishmania major phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.0381
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0047 0.002 0.0184
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.0398
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0091 0.0049 0.0137
Brugia malayi N-terminal motif family protein 0.0185 0.011 0.1428
Brugia malayi hypothetical protein 0.0126 0.0072 0.0925
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0015 0.0137
Brugia malayi G protein-coupled receptor 0.0126 0.0072 0.0925
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0113 0.0063 0.0062
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0126 0.0072 0.0071
Brugia malayi hypothetical protein 0.0022 0.0004 0.0034
Loa Loa (eye worm) acetyltransferase 0.0158 0.0092 0.0856
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0005 0.0004
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1139 0.0729 0.9737
Schistosoma mansoni chromobox protein 0.0025 0.0006 0.005
Schistosoma mansoni lipoxygenase 0.0061 0.0029 0.0266
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0026 0.0325
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0067 0.0872
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0001 0.0005
Onchocerca volvulus 0.0026 0.0007 0.029
Loa Loa (eye worm) phosphatidylinositol 3 0.0232 0.014 0.1305
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0047 0.002 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Trichomonas vaginalis sucrase-isomaltase, putative 0.0051 0.0023 0.0281
Echinococcus granulosus tachykinin peptides receptor 99D 0.0126 0.0072 0.0071
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0126 0.0072 0.0925
Loa Loa (eye worm) hypothetical protein 0.0053 0.0024 0.0222
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0176 0.0104 0.0103
Echinococcus granulosus Chromobox protein 3 0.0025 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0048 0.002 0.0187
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.002 0.0054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0022 0.0266
Schistosoma mansoni opsin-like receptor 0.0126 0.0072 0.0664
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0047 0.002 0.0052
Trichomonas vaginalis importin beta-1, putative 0.0126 0.0072 0.0931
Onchocerca volvulus 0.0126 0.0072 0.4394
Trypanosoma brucei importin beta-1 subunit, putative 0.0156 0.0091 0.1196
Entamoeba histolytica protein kinase rad3, putative 0.0649 0.0411 0.5477
Toxoplasma gondii melibiase subfamily protein 0.0113 0.0063 0.0846
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.1151 0.0737 0.9838
Loa Loa (eye worm) hypothetical protein 0.0433 0.027 0.2526
Leishmania major cytochrome p450-like protein 0.0071 0.0036 0.0094
Loa Loa (eye worm) cytochrome P450 0.0044 0.0018 0.0163
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0026 0.0007 0.0058
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus FTZ F1 alpha 0.0026 0.0007 0.0006
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0176 0.0104 0.0965
Mycobacterium ulcerans endonuclease IV 0.0084 0.0044 0.2447
Trichomonas vaginalis PIKK family atypical protein kinase 0.1158 0.0742 0.9899
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.005 0.0022 0.0274
Loa Loa (eye worm) Smad1 0.0018 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0063 0.0582
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0005 0.0004
Onchocerca volvulus 0.0126 0.0072 0.4394
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.0026 0.0242
Trichomonas vaginalis alpha-glucosidase, putative 0.0051 0.0023 0.0281
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0001 0.0003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.119 0.0763 1
Echinococcus granulosus neuropeptide Y receptor 0.0126 0.0072 0.0071
Brugia malayi hypothetical protein 0.0068 0.0034 0.0429
Schistosoma mansoni kinase 0.009 0.0048 0.0442
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0044 0.0018 0.0427
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0126 0.0072 0.0664
Loa Loa (eye worm) phosphatidylinositol 3 0.0232 0.014 0.1305
Onchocerca volvulus 0.0134 0.0077 0.4717
Loa Loa (eye worm) hypothetical protein 0.0054 0.0024 0.0224
Echinococcus granulosus hypothetical protein 0.0126 0.0072 0.0071
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0176 0.0104 0.0282
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0025 0.0006 0.0079
Toxoplasma gondii ABC1 family protein 0.0101 0.0055 0.0744
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0006 0.0051
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0015 0.0184
Echinococcus multilocularis thioredoxin glutathione reductase 0.0136 0.0078 0.0077
Echinococcus multilocularis importin subunit beta 1 0.0156 0.0091 0.009
Leishmania major hypothetical protein, unknown function 0.0232 0.014 0.0381
Schistosoma mansoni fkbp-rapamycin associated protein 0.0649 0.0411 0.3842
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0004 0.004
Echinococcus multilocularis musashi 0.0135 0.0077 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0091 0.0049 0.0628
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.003
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0232 0.014 0.8057
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0013 0.0013
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0009 0.0008
Brugia malayi Glycosyl hydrolases family 31 protein 0.0232 0.014 0.1826
Echinococcus multilocularis chromobox protein 2 0.0025 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0126 0.0072 0.0665
Echinococcus granulosus tumor protein p63 0.0434 0.0272 0.0271
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0044 0.0018 0.0047
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.119 0.0763 0.0762
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0232 0.014 0.0139
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0026 0.0007 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0006 0.0048
Trypanosoma brucei protein kinase, putative 0.0057 0.0026 0.0334
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0063 0.0582
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0059 0.0028 0.1624
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0012 0.0168
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0019 0.0169
Schistosoma mansoni amine GPCR 0.0126 0.0072 0.0664
Brugia malayi Bromodomain containing protein 0.0054 0.0025 0.0307
Loa Loa (eye worm) glutaminase 0.0293 0.018 0.1676
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0007 0.0073
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0091 0.0049 0.0048
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0006 0.0079
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0058
Brugia malayi hypothetical protein 0.0134 0.0076 0.099
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0004 0.0028
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0068 0.0034 0.0033
Toxoplasma gondii histone lysine methyltransferase SET1 0.0214 0.0128 0.1731
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0011 0.0601
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0035 0.0012 0.0144
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0007 0.0057
Brugia malayi jmjC domain containing protein 0.0066 0.0032 0.0409
Loa Loa (eye worm) hypothetical protein 0.0084 0.0044 0.041
Plasmodium vivax hypothetical protein, conserved 0.0048 0.002 0.1172
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0024 0.0217
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0094 0.0051 0.005
Plasmodium vivax hypothetical protein 0.0232 0.014 0.8057
Echinococcus granulosus serotonin receptor 0.0126 0.0072 0.0071
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0804 0.0512 0.4783
Onchocerca volvulus 0.0124 0.007 0.4298
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.0026 0.0069
Echinococcus granulosus dnaJ subfamily B 0.0316 0.0195 0.0194
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0071 0.0036 0.0035
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0051 0.0023 0.0281
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0126 0.0072 0.0664
Giardia lamblia Phosphatidylinositol 4-kinase 0.0232 0.014 0.1846
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0011 0.0114
Schistosoma mansoni hypothetical protein 0.0203 0.0121 0.1129
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0223 0.0135 0.1256
Brugia malayi follicle stimulating hormone receptor 0.0561 0.0354 0.4633
Echinococcus multilocularis rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0804 0.0512 0.0511
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0629 0.0398 0.114
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Schistosoma mansoni biogenic amine (5HT) receptor 0.0126 0.0072 0.0664
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0044 0.0018 0.0971
Schistosoma mansoni tar DNA-binding protein 0.0223 0.0135 0.1255
Onchocerca volvulus 0.0019 0.0002 0.0001
Echinococcus granulosus chromobox protein 1 0.0089 0.0047 0.0047
Onchocerca volvulus 0.0263 0.016 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.117 0.0749 0.2147
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0028 0.0344
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0019 0.0002 0.0089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.116 0.0743 0.9919
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0051
Loa Loa (eye worm) phosphatidylinositol 3 0.0739 0.047 0.439
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0104 0.136
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.0067 0.3081
Echinococcus multilocularis microtubule associated protein 2 0.0596 0.0377 0.0376
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0044 0.0018 0.0164
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0099 0.0054 0.0053
Echinococcus granulosus rhodopsin orphan GPCR 0.0126 0.0072 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0022 0.0271
Echinococcus multilocularis geminin 0.035 0.0217 0.0216
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.117 0.0749 1
Brugia malayi larval opioid receptor 0.0126 0.0072 0.0925
Echinococcus multilocularis neuropeptide receptor A26 0.0423 0.0264 0.0263
Echinococcus granulosus 7TM GPCR rhodopsin 0.0126 0.0072 0.0071

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 8.5 nM Binding affinity towards Tachykinin receptor 1 binding in guinea pig cerebral cortex membranes was determined using [3H]-SP as the radioligand ChEMBL. No reference
IC50 (binding) = 8.5 nM Binding affinity towards Tachykinin receptor 1 binding in guinea pig cerebral cortex membranes was determined using [3H]-SP as the radioligand ChEMBL. No reference
IC50 (binding) = 110 nM Binding affinity towards Tachykinin receptor 1 in rat cerebral cortex membranes was determined by using 125 [I]-BHSP as radioligand ChEMBL. No reference
IC50 (binding) = 110 nM Binding affinity towards Tachykinin receptor 1 in rat cerebral cortex membranes was determined by using 125 [I]-BHSP as radioligand ChEMBL. No reference
IC50 (binding) >= 100000 nM Ability to displace the binding of [125I]-iodohistidyl-NKA to Tachykinin receptor 2 in hamster urinary bladder membranes was determined. ChEMBL. No reference
IC50 (binding) >= 100000 nM Ability to displace the binding of [3H]-Senktide to Tachykinin receptor 3 in rat cerebral cortex membranes was determined. ChEMBL. No reference
IC50 (binding) >= 100000 nM Ability to displace the binding of [125I]-iodohistidyl-NKA to Tachykinin receptor 2 in hamster urinary bladder membranes was determined. ChEMBL. No reference
IC50 (binding) >= 100000 nM Ability to displace the binding of [3H]-Senktide to Tachykinin receptor 3 in rat cerebral cortex membranes was determined. ChEMBL. No reference
Ratio (binding) = 13 Ratio of binding affinity for NK1 receptor in guinea pig to that of rat was determined ChEMBL. No reference
Ratio (binding) = 13 Ratio of binding affinity for NK1 receptor in guinea pig to that of rat was determined ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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