Detailed information for compound 311849

Basic information

Technical information
  • TDR Targets ID: 311849
  • Name: 2,8-dihydroxy-3-(3-oxo-1-phenylbutyl)chromen- 4-one
  • MW: 324.327 | Formula: C19H16O5
  • H donors: 2 H acceptors: 4 LogP: 2.42 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)CC(c1c(O)oc2c(c1=O)cccc2O)c1ccccc1
  • InChi: 1S/C19H16O5/c1-11(20)10-14(12-6-3-2-4-7-12)16-17(22)13-8-5-9-15(21)18(13)24-19(16)23/h2-9,14,21,23H,10H2,1H3
  • InChiKey: RCTGERXIFCOAHF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2,8-dihydroxy-3-(3-oxo-1-phenyl-butyl)chromen-4-one
  • 2,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-4-one
  • 2,8-dihydroxy-3-(3-keto-1-phenyl-butyl)chromone
  • 8-hydroxywarfarin
  • 2,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-4-chromenone
  • 17834-04-7
  • NCGC00165931-01
  • 2H-1-Benzopyran-2-one, 4,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0186 0.0578 0.0578
Echinococcus granulosus notch 0.0206 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0095 0.012 0.0105
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0188 0.0589 0.0543
Plasmodium vivax ferrodoxin reductase, putative 0.0188 0.0589 0.0542
Echinococcus granulosus mitogen activated protein kinase 11 0.0158 0.0438 0.0438
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Echinococcus multilocularis cyclin dependent kinase 0.0118 0.0238 0.0238
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0078 0.0033 0.0033
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0707 0.3228 1
Onchocerca volvulus 0.0206 0.0683 0.3548
Echinococcus granulosus protein jagged 2 0.0206 0.0683 0.0683
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0233 0.082 0.082
Schistosoma mansoni tyrosine kinase 0.0541 0.2383 0.2383
Brugia malayi Sex muscle abnormal protein 5 0.009 0.0094 0.0072
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0145 0.037 0.0321
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Toxoplasma gondii aurora kinase 0.0145 0.037 0.0322
Onchocerca volvulus 0.0381 0.157 0.8229
Loa Loa (eye worm) hypothetical protein 0.0386 0.1599 0.1586
Brugia malayi Protein kinase domain containing protein 0.0187 0.0585 0.0564
Schistosoma mansoni tyrosine kinase 0.044 0.1869 0.1869
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.204 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0338 0.0898
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0138 0.0338 0.0316
Echinococcus multilocularis activin receptor type 0.0081 0.0049 0.0049
Brugia malayi Immunoglobulin I-set domain containing protein 0.0145 0.0373 0.0351
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0144 0.0366 0.0366
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0338 0.0898
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0155 0.0425 0.0414
Schistosoma mansoni cell adhesion molecule 0.0207 0.069 0.069
Plasmodium falciparum calcium-dependent protein kinase 4 0.0101 0.0149 0.01
Brugia malayi STE20-like kinase MST 0.0253 0.0922 0.0901
Toxoplasma gondii AGC kinase 0.0113 0.0209 0.0161
Trypanosoma brucei SNF1-related protein kinases, putative 0.009 0.0092 0.0043
Brugia malayi Protein kinase domain containing protein 0.01 0.0142 0.012
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0101 0.0149 0.01
Leishmania major protein kinase A catalytic subunit isoform 2 0.0113 0.0209 0.0161
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0142 0.0357 0.0357
Schistosoma mansoni serine/threonine kinase 0.0214 0.0725 0.0725
Schistosoma mansoni cell adhesion molecule 0.0499 0.2169 0.2169
Loa Loa (eye worm) TK protein kinase 0.0133 0.0309 0.0295
Brugia malayi MAP kinase sur-1 0.0084 0.0064 0.0041
Loa Loa (eye worm) TK/ROR protein kinase 0.0142 0.0357 0.0342
Brugia malayi Protein kinase domain containing protein 0.0186 0.0583 0.0561
Brugia malayi EGF-like domain containing protein 0.0206 0.0683 0.0662
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0188 0.0589 0.169
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0209 0.0198
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0371 0.1521 0.1521
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0112 0.0207 0.0207
Echinococcus multilocularis epidermal growth factor receptor 0.0395 0.1643 0.1643
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0325 0.1288 0.1275
Giardia lamblia Thioredoxin reductase 0.0188 0.0589 0.1669
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0112 0.0207 0.0207
Loa Loa (eye worm) CDC7 protein kinase 0.009 0.0094 0.0079
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0122 0.0255 0.0244
Echinococcus multilocularis 0.0095 0.012 0.012
Brugia malayi protein unc-22 0.0145 0.0373 0.0351
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Onchocerca volvulus 0.0206 0.0683 0.3548
Entamoeba histolytica protein kinase, putative 0.0074 0.0012 0.0053
Onchocerca volvulus 0.032 0.1261 0.6599
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Echinococcus multilocularis calcium activated potassium channel 0.0134 0.0317 0.0317
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0223 0.0768 0.0768
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0184 0.057 0.057
Schistosoma mansoni tyrosine kinase 0.0137 0.0331 0.0331
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.02 0.0653 0.0653
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0995 0.4691 0.4691
Schistosoma mansoni glutamate synthase 0.0188 0.0589 0.0589
Echinococcus granulosus activin receptor type 0.0081 0.0049 0.0049
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.009 0.0092 0.0042
Loa Loa (eye worm) hypothetical protein 0.0189 0.0596 0.0582
Echinococcus granulosus defective proboscis extension response 0.0371 0.1521 0.1521
Loa Loa (eye worm) hypothetical protein 0.0188 0.0589 0.0575
Toxoplasma gondii selenide, water dikinase 0.0188 0.0589 0.0543
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0095 0.012 0.0105
Brugia malayi Protein kinase domain containing protein 0.0114 0.0215 0.0192
Echinococcus granulosus Vam6:Vps39 protein 0.0109 0.019 0.019
Echinococcus multilocularis 0.0152 0.0408 0.0408
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.009 0.0092 0.0077
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0519 0.2274 0.2257
Echinococcus multilocularis roundabout 2 0.0223 0.0768 0.0768
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0188 0.0589 0.0543
Echinococcus multilocularis hemicentin 1 0.0207 0.069 0.069
Schistosoma mansoni septate junction protein 0.0207 0.069 0.069
Schistosoma mansoni notch 0.0206 0.0683 0.0683
Echinococcus granulosus calcium activated potassium channel 0.0134 0.0317 0.0317
Schistosoma mansoni nck2/grb4 0.009 0.0094 0.0094
Brugia malayi serine/threonine kinase 12 0.0145 0.037 0.0348
Schistosoma mansoni tyrosine kinase 0.0223 0.0768 0.0768
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0892 0.0892
Echinococcus multilocularis 0.017 0.0497 0.0497
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0316 0.0316
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Echinococcus granulosus neural cadherin 0.0206 0.0683 0.0683
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0188 0.0589 0.0568
Brugia malayi serine/threonine-protein kinase PAK 7 0.0229 0.08 0.0779
Giardia lamblia Kinase, CMGC MAPK 0.0084 0.0064 0.001
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0188 0.0589 0.0579
Toxoplasma gondii AGC kinase 0.0287 0.1095 0.1051
Entamoeba histolytica p21-activated kinase 0.0095 0.012 0.0524
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0249 0.0899 0.0899
Loa Loa (eye worm) TK protein kinase 0.0281 0.1062 0.1049
Trichomonas vaginalis AGC family protein kinase 0.0186 0.0583 0.167
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0081 0.0049 0.0038
Brugia malayi basement membrane proteoglycan 0.0112 0.0207 0.0184
Giardia lamblia Kinase, CMGC CDK 0.0118 0.0238 0.0559
Schistosoma mansoni hypothetical protein 0.011 0.0197 0.0197
Brugia malayi EGF-like domain containing protein 0.0206 0.0683 0.0662
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0223 0.0768 0.0768
Echinococcus granulosus tyrosine protein kinase HCK 0.0133 0.0309 0.0309
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0118 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0135 0.0324 0.031
Echinococcus multilocularis down syndrome cell adhesion 0.0095 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0084 0.0062 0.0047
Leishmania major casein kinase II, putative 0.01 0.0145 0.0096
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0158 0.0438 0.039
Giardia lamblia Aurora kinase 0.0145 0.037 0.0977
Mycobacterium ulcerans ferredoxin reductase 0.0188 0.0589 0.1455
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0122 0.0255 0.0244
Brugia malayi Protein kinase domain 0.0086 0.0075 0.0052
Echinococcus granulosus mitogen activated protein kinase 3 0.0084 0.0064 0.0064
Onchocerca volvulus 0.0206 0.0683 0.3548
Plasmodium vivax unspecified product 0.01 0.0145 0.0095
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0188 0.0589 0.0589
Echinococcus granulosus casein kinase I delta 0.0109 0.0188 0.0188
Plasmodium falciparum apical sushi protein 0.0381 0.157 0.1528
Echinococcus multilocularis titin 0.0145 0.0373 0.0373
Brugia malayi intracellular kinase 0.0128 0.0287 0.0265
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0094 0.0129
Brugia malayi Animal haem peroxidase family protein 0.0095 0.012 0.0097
Loa Loa (eye worm) AGC/PKG protein kinase 0.0134 0.0316 0.0302
Loa Loa (eye worm) notch protein 0.0206 0.0683 0.0669
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Schistosoma mansoni protein kinase 0.0081 0.0049 0.0049
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0209 0.0194
Echinococcus multilocularis lachesin 0.0207 0.069 0.069
Trichomonas vaginalis CAMK family protein kinase 0.0126 0.0275 0.0701
Entamoeba histolytica PH domain containing protein kinase, putative 0.0164 0.047 0.206
Entamoeba histolytica protein kinase, putative 0.0101 0.0149 0.0652
Schistosoma mansoni cell adhesion molecule 0.0095 0.012 0.012
Giardia lamblia Kinase, NEK 0.0135 0.0324 0.0831
Brugia malayi Immunoglobulin I-set domain containing protein 0.0223 0.0768 0.0747
Loa Loa (eye worm) hypothetical protein 0.0223 0.0768 0.0754
Echinococcus granulosus nervana 2 0.0121 0.0249 0.0249
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0095 0.012 0.012
Echinococcus multilocularis protein kinase c epsilon type 0.0208 0.0695 0.0695
Onchocerca volvulus 0.01 0.0142 0.0691
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0141 0.0351 0.0351
Echinococcus multilocularis insulin receptor 0.044 0.1869 0.1869
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Loa Loa (eye worm) hypothetical protein 0.0579 0.2575 0.2564
Echinococcus multilocularis hemicentin 1 0.0207 0.069 0.069
Schistosoma mansoni serine/threonine protein kinase 0.0468 0.2014 0.2014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.322
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0188 0.0589 0.0579
Schistosoma mansoni tyrosine kinase 0.0223 0.0768 0.0768
Plasmodium falciparum serine/threonine protein kinase, putative 0.0145 0.037 0.0322
Loa Loa (eye worm) hypothetical protein 0.014 0.0348 0.0334
Plasmodium falciparum casein kinase 1 0.0109 0.0188 0.0139
Loa Loa (eye worm) hypothetical protein 0.0101 0.0149 0.0134
Brugia malayi Prion-like- 0.0095 0.012 0.0097
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0162 0.0461 0.0446
Entamoeba histolytica protein kinase, putative 0.0138 0.0338 0.1481
Entamoeba histolytica protein kinase domain containing protein 0.01 0.0145 0.0636
Schistosoma mansoni notch 0.0206 0.0683 0.0683
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0396 0.1647 0.1647
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Echinococcus granulosus basement membrane specific heparan sulfate 0.0112 0.0207 0.0207
Plasmodium falciparum protein serine/threonine kinase-1 0.0152 0.0411 0.0363
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0206 0.0683 0.0662
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0426 0.18 0.18
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Loa Loa (eye worm) hypothetical protein 0.0386 0.1599 0.1586
Onchocerca volvulus Putative cubilin 0.0206 0.0683 0.3548
Echinococcus multilocularis 0.0118 0.0235 0.0235
Trichomonas vaginalis STE family protein kinase 0.0135 0.0324 0.0854
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Echinococcus granulosus CDC7 cell division cycle 7 0.009 0.0094 0.0094
Echinococcus multilocularis roundabout 2 0.0223 0.0768 0.0768
Schistosoma mansoni serine/threonine protein kinase 0.0208 0.0695 0.0695
Echinococcus granulosus neurogenic locus protein delta 0.0206 0.0683 0.0683
Echinococcus granulosus tyrosine protein kinase 0.0281 0.1062 0.1062
Entamoeba histolytica hypothetical protein 0.0371 0.1521 0.6668
Echinococcus granulosus lachesin 0.0207 0.069 0.069
Brugia malayi cell division control protein 2 homolog 0.0118 0.0238 0.0215
Entamoeba histolytica protein kinase, putative 0.0122 0.0255 0.1117
Echinococcus multilocularis aurora kinase A 0.0145 0.037 0.037
Loa Loa (eye worm) TK protein kinase 0.0343 0.1378 0.1365
Entamoeba histolytica protein kinase, putative 0.0086 0.0075 0.033
Entamoeba histolytica protein kinase, putative 0.0122 0.0255 0.1117
Schistosoma mansoni growth factor receptor-bound protein 0.0092 0.0104 0.0104
Echinococcus granulosus tyrosine protein kinase ABL1 0.01 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.011 0.0197 0.0182
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0707 0.3228 0.3194
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0166 0.0481 0.0481
Schistosoma mansoni glutamate synthase 0.0188 0.0589 0.0589
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Brugia malayi hypothetical protein 0.0109 0.019 0.0168
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Brugia malayi map kinase activated protein kinase protein 2 0.0387 0.1603 0.1584
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0188 0.0589 0.1455
Loa Loa (eye worm) hypothetical protein 0.0109 0.019 0.0175
Schistosoma mansoni hypothetical protein 0.0095 0.012 0.012
Brugia malayi p70 ribosomal S6 kinase beta 0.0287 0.1095 0.1074
Echinococcus multilocularis mitogen activated protein kinase 11 0.0158 0.0438 0.0438
Schistosoma mansoni tyrosine kinase 0.0395 0.1643 0.1643
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0213 0.072 0.072
Trichomonas vaginalis STE family protein kinase 0.0086 0.0075 0.0071
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0084 0.0064 0.0015
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Giardia lamblia Kinase, STE STE20 0.0086 0.0075 0.0046
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Brugia malayi Disorganized muscle protein 1 0.0095 0.012 0.0097
Mycobacterium ulcerans hypothetical protein 0.0188 0.0589 0.1455
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0317 0.0317
Schistosoma mansoni serine/threonine kinase 0.0166 0.0481 0.0481
Trypanosoma brucei protein kinase, putative 0.0128 0.0287 0.0239
Plasmodium falciparum glutathione reductase 0.204 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0128 0.0287 0.1257
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0347 0.1397 0.1397
Echinococcus granulosus casein kinase i 0.0109 0.0188 0.0188
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Onchocerca volvulus Netrin receptor homolog 0.0123 0.0263 0.1328
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0188 0.0589 0.0543
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0226 0.0786 0.0786
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0707 0.3228 0.3194
Echinococcus multilocularis thioredoxin glutathione reductase 0.204 1 1
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.0238 0.0238
Entamoeba histolytica protein kinase domain containing protein 0.0138 0.0338 0.1481
Echinococcus granulosus tyrosine protein kinase Srms 0.0498 0.2164 0.2164
Echinococcus multilocularis serine:threonine protein kinase N2 0.0166 0.0481 0.0481
Brugia malayi Protein kinase domain containing protein 0.0281 0.1062 0.1042
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0238 0.0583
Loa Loa (eye worm) hypothetical protein 0.0423 0.1787 0.1774
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.044 0.1873 0.1861
Loa Loa (eye worm) AGC/NDR protein kinase 0.0166 0.0481 0.0467
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0347 0.1397 0.1397
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.069 0.0669
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.034 0.1362 0.1349
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0238 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0092 0.0092
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Echinococcus granulosus protein tyrosine kinase 0.0541 0.2383 0.2383
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0707 0.3228 0.3228
Loa Loa (eye worm) hypothetical protein 0.0112 0.0207 0.0192
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.322
Loa Loa (eye worm) hypothetical protein 0.018 0.0552 0.0538
Brugia malayi Cyclin, N-terminal domain containing protein 0.0513 0.2243 0.2225
Echinococcus multilocularis cyclin dependent kinase 19 0.0694 0.3162 0.3162
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0287 0.1095 0.1081
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0135 0.0324 0.0276
Loa Loa (eye worm) TK/ABL protein kinase 0.01 0.0142 0.0127
Giardia lamblia Kinase, AGC PKA 0.0113 0.0209 0.0469
Entamoeba histolytica PH domain containing protein kinase, putative 0.0164 0.047 0.206
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0238 0.0238
Brugia malayi serine/threonine-protein kinase plk-2 0.0266 0.0989 0.0968
Echinococcus multilocularis tyrosine protein kinase 0.0281 0.1062 0.1062
Brugia malayi Protein kinase domain containing protein 0.0198 0.0644 0.0623
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0223 0.0768 0.0768
Loa Loa (eye worm) camk/dcamkl protein kinase 0.015 0.0397 0.0382
Brugia malayi Protein kinase domain containing protein 0.0694 0.3162 0.3147
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0257 0.0944 0.093
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0223 0.0768 0.0768
Schistosoma mansoni titin 0.0095 0.012 0.012
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0128 0.0284 0.027
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0188 0.0589 0.0543
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0149 0.0149
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0145 0.0373 0.0359
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.072 0.072
Schistosoma mansoni protein kinase 0.0191 0.0605 0.0605
Loa Loa (eye worm) hypothetical protein 0.0208 0.0691 0.0677
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0707 0.3228 0.3194
Trichomonas vaginalis glutamate synthase, putative 0.0188 0.0589 0.169
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0207 0.069 0.069
Schistosoma mansoni tyrosine kinase 0.0077 0.0029 0.0029
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0188 0.0589 0.0543
Trichomonas vaginalis glutamate synthase, putative 0.0188 0.0589 0.169
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0188 0.0589 0.0589
Loa Loa (eye worm) TK/EGFR protein kinase 0.0598 0.2675 0.2664
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0095 0.012 0.012
Brugia malayi probable protein kinase 0.0261 0.0962 0.0942
Echinococcus granulosus tyrosine protein kinase Fyn 0.0223 0.0768 0.0768
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0707 0.3228 1
Entamoeba histolytica casein kinase 1, putative 0.0109 0.0188 0.0822
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0082 0.0053 0.0053
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0112 0.0207 0.0207
Trichomonas vaginalis STE family protein kinase 0.0086 0.0075 0.0071
Onchocerca volvulus 0.009 0.0094 0.0436
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0188 0.0188
Onchocerca volvulus Serine\/threonine kinase homolog 0.0163 0.0462 0.2382
Brugia malayi protein kinase C II. 0.0208 0.0695 0.0674
Toxoplasma gondii thioredoxin reductase 0.204 1 1
Mycobacterium ulcerans monoxygenase 0.0188 0.0589 0.1455
Echinococcus granulosus cyclin dependent kinase 1 0.0118 0.0238 0.0238
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0188 0.0589 0.0589
Loa Loa (eye worm) hypothetical protein 0.0302 0.117 0.1156
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0223 0.0768 0.0768
Echinococcus multilocularis casein kinase i 0.0109 0.0188 0.0188
Loa Loa (eye worm) TK protein kinase 0.0335 0.134 0.1327
Schistosoma mansoni hypothetical protein 0.0099 0.0141 0.0141
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0232 0.0814 0.0814
Entamoeba histolytica protein kinase, putative 0.0133 0.0309 0.1357
Schistosoma mansoni netrin receptor unc5 0.0141 0.035 0.035
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0188 0.0589 0.0589
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0152 0.0411 0.0363
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.322
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0095 0.0121 0.0121
Echinococcus multilocularis neurogenic locus protein delta 0.0206 0.0683 0.0683
Echinococcus multilocularis tyrosine protein kinase shark 0.0308 0.1201 0.1201
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Echinococcus multilocularis twitchin 0.013 0.0296 0.0296
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Loa Loa (eye worm) hypothetical protein 0.0139 0.0344 0.033
Trypanosoma cruzi SNF1-related protein kinases, putative 0.009 0.0092 0.0081
Echinococcus multilocularis neuroglian 0.0466 0.2005 0.2005
Echinococcus granulosus protein kinase C gamma type 0.0206 0.0684 0.0684
Echinococcus multilocularis nervana 2 0.0121 0.0249 0.0249
Schistosoma mansoni vam6/vps39 related 0.0109 0.019 0.019
Onchocerca volvulus 0.01 0.0142 0.0691
Onchocerca volvulus Serine\/threonine kinase homolog 0.0266 0.0989 0.5162
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0386 0.1599 0.1586
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0198 0.0644 0.0644
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0223 0.0768 0.0768
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Echinococcus granulosus tyrosine protein kinase shark 0.0308 0.1201 0.1201
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0113 0.0209 0.0161
Echinococcus multilocularis c src tyrosine kinase 0.0137 0.0331 0.0331
Plasmodium falciparum glycogen synthase kinase 3 0.0128 0.0287 0.0239
Echinococcus granulosus c-Jun N-terminal kinases 0.026 0.0959 0.0959
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0223 0.0768 0.0768
Schistosoma mansoni hypothetical protein 0.0099 0.0141 0.0141
Brugia malayi Immunoglobulin domain containing protein 0.0112 0.0207 0.0184
Echinococcus multilocularis protein kinase c iota type 0.0288 0.11 0.11
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.009 0.0092 0.0043
Echinococcus multilocularis Immunoglobulin subtype 0.0112 0.0207 0.0207
Brugia malayi Protein kinase domain containing protein 0.0082 0.0053 0.003
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0125 0.0274 0.0225
Plasmodium vivax apical sushi protein, putative 0.0381 0.157 0.1527
Brugia malayi Calcium binding EGF domain containing protein 0.0206 0.0683 0.0662
Brugia malayi Immunoglobulin I-set domain containing protein 0.0123 0.0261 0.0239
Entamoeba histolytica protein kinase domain containing protein 0.02 0.0653 0.2865
Loa Loa (eye worm) AGC/PKN protein kinase 0.0293 0.1124 0.1111
Echinococcus granulosus titin 0.0145 0.0373 0.0373
Loa Loa (eye worm) hypothetical protein 0.0207 0.069 0.0676
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0206 0.0683 0.3548
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Entamoeba histolytica protein kinase domain containing protein 0.0145 0.037 0.1623
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0061 0.0061
Schistosoma mansoni laminin gamma-3 chain 0.0206 0.0683 0.0683
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0188 0.0589 0.0543
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.322
Loa Loa (eye worm) TK/ALK protein kinase 0.0278 0.1046 0.1033
Toxoplasma gondii histone kinase SNF1, putative 0.009 0.0092 0.0043
Brugia malayi kettin 0.0095 0.012 0.0097
Schistosoma mansoni hypothetical protein 0.0095 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Brugia malayi EGF-like domain containing protein 0.0206 0.0683 0.0662
Echinococcus multilocularis myosin iiia 0.0085 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0081 0.0081
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0396 0.1647 0.1647
Echinococcus multilocularis serine:threonine protein kinase N2 0.0293 0.1124 0.1124
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0114 0.0215 0.02
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Echinococcus multilocularis dual specificity 0.0138 0.0338 0.0338
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.024 0.0856 0.0856
Schistosoma mansoni adapter molecule crk 0.009 0.0094 0.0094
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0109 0.019 0.0179
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.024 0.0856 0.0856
Trypanosoma cruzi casein kinase, putative 0.0109 0.0188 0.0176
Brugia malayi Cyclin C 0.1034 0.4887 0.4876
Schistosoma mansoni titin 0.0145 0.0373 0.0373
Schistosoma mansoni tyrosine kinase 0.044 0.1869 0.1869
Brugia malayi Protein kinase domain containing protein 0.0347 0.1397 0.1377
Schistosoma mansoni titin 0.0095 0.012 0.012
Trypanosoma brucei cdc2-related kinase 1 0.0118 0.0238 0.0189
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0207 0.069 0.3584
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0707 0.3228 0.3194
Loa Loa (eye worm) hypothetical protein 0.0579 0.2575 0.2564
Schistosoma mansoni hypothetical protein 0.0112 0.0207 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0092 0.0092
Brugia malayi protein kinase C3,putative 0.0156 0.0431 0.0409
Echinococcus granulosus cyclin dependent kinase 19 0.0694 0.3162 0.3162
Brugia malayi Egg laying defective protein 4 0.0134 0.0316 0.0294
Trichomonas vaginalis AGC family protein kinase 0.0145 0.037 0.1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0707 0.3228 0.3194
Giardia lamblia Kinase, CMGC CK2 0.01 0.0145 0.0266
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0145 0.037 0.1623
Onchocerca volvulus 0.0095 0.0121 0.0579
Echinococcus multilocularis casein kinase I gamma 0.0211 0.0706 0.0706
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0188 0.0589 0.169
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0138 0.0338 0.0327
Brugia malayi Cadherin domain containing protein 0.0206 0.0683 0.0662
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0094 0.0129
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0088 0.0081 0.0356
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0155 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.009 0.0092 0.0077
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0188 0.0589 0.2584
Giardia lamblia Kinase, CAMK CAMKL 0.009 0.0092 0.0099
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0707 0.3228 0.3228
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0188 0.0589 0.169
Echinococcus granulosus dual specificity 0.0138 0.0338 0.0338
Loa Loa (eye worm) AGC/AKT protein kinase 0.0296 0.1139 0.1126
Echinococcus multilocularis dual specificity 0.0122 0.0255 0.0255
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0109 0.0188 0.0173
Schistosoma mansoni notch 0.0206 0.0683 0.0683
Echinococcus granulosus protein jagged 2 0.0206 0.0683 0.0683
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0188 0.0589 0.1669
Echinococcus multilocularis titin 0.0095 0.012 0.012
Entamoeba histolytica protein kinase , putative 0.0145 0.037 0.1623
Echinococcus multilocularis dual specificity 0.0138 0.0338 0.0338
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0188 0.0425
Echinococcus granulosus mitogen activated protein kinase 0.0084 0.0064 0.0064
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0084 0.0061 0.0046
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0118 0.0238 0.0223
Echinococcus granulosus dual specificity 0.0138 0.0338 0.0338
Brugia malayi Protein kinase domain containing protein 0.0122 0.0255 0.0233
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Leishmania major protein kinase, putative 0.0085 0.0068 0.0019
Brugia malayi pregnancy-associated plasma protein-A 0.0381 0.157 0.155
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0206 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.008 0.004 0.0025
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0209 0.0198
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0707 0.3228 0.2803
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0163 0.0462 0.0462
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Entamoeba histolytica protein kinase, putative 0.0128 0.0287 0.1257
Trypanosoma brucei rac serine-threonine kinase, putative 0.0296 0.1139 0.1095
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0085 0.0068 0.03
Schistosoma mansoni titin 0.0095 0.012 0.012
Leishmania major protein kinase A catalytic subunit isoform 1 0.0113 0.0209 0.0161
Brugia malayi Peroxidasin 0.0208 0.0691 0.067
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0064 0.0052
Echinococcus granulosus Immunoglobulin 0.0371 0.1521 0.1521
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0094 0.0113 0.0113
Echinococcus multilocularis neurogenic locus notch protein 0.0206 0.0683 0.0683
Entamoeba histolytica PH domain containing protein kinase, putative 0.0122 0.0254 0.1112
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Echinococcus granulosus dual specificity 0.0138 0.0338 0.0338
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0209 0.0198
Echinococcus multilocularis CDC7 cell division cycle 7 0.009 0.0094 0.0094
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0485 0.21 0.21
Brugia malayi Serine/threonine-protein kinase SULU 0.0219 0.0751 0.0729
Loa Loa (eye worm) hypothetical protein 0.0371 0.1523 0.151
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0694 0.3162 0.3152
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.069 0.0669
Echinococcus multilocularis peroxidasin 0.0208 0.0691 0.0691
Loa Loa (eye worm) TK/FER protein kinase 0.0396 0.1647 0.1634
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.322
Onchocerca volvulus Slit protein homolog 0.0234 0.0825 0.4298
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Loa Loa (eye worm) hypothetical protein 0.0371 0.1521 0.1509
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0229 0.08 0.0786
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0118 0.0238 0.0189
Echinococcus multilocularis notch 0.0206 0.0683 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.0706 0.0706
Loa Loa (eye worm) cyclin domain-containing protein 0.0513 0.2243 0.2231
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0084 0.0064 0.0015
Echinococcus multilocularis neural cadherin 0.0206 0.0683 0.0683
Brugia malayi Hr1 repeat family protein 0.0293 0.1124 0.1104
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0084 0.0064 0.0015
Echinococcus granulosus cyclin dependent kinase 5 0.0118 0.0238 0.0238
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0094 0.0113 0.0098
Trichomonas vaginalis AGC family protein kinase 0.0145 0.037 0.1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0123 0.0261 0.0247
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0188 0.0188
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0197 0.0175
Echinococcus granulosus tyrosine kinase 0.0186 0.0578 0.0578
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0158 0.0438 0.0427
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0751 0.0751
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0188 0.0589 0.0543
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0588 0.2624 0.2613
Echinococcus multilocularis tyrosine protein kinase Abl 0.0137 0.0331 0.0331
Schistosoma mansoni protein kinase 0.0361 0.1467 0.1467
Onchocerca volvulus 0.0128 0.0287 0.1454
Echinococcus granulosus peroxidasin 0.0208 0.0691 0.0691
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0198 0.0644 0.0644
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0155 0.0425 0.0377
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0163 0.0462 0.0462
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0223 0.0768 0.0768
Loa Loa (eye worm) protein kinase domain-containing protein 0.0211 0.0706 0.0692
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0214 0.0725 0.0711
Schistosoma mansoni tyrosine kinase 0.0254 0.0927 0.0927
Brugia malayi Protein kinase domain containing protein 0.0211 0.0706 0.0685
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0084 0.0064 0.0049
Echinococcus granulosus c src tyrosine kinase 0.0137 0.0331 0.0331
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0112 0.0207 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.057 0.057
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Schistosoma mansoni hypothetical protein 0.0112 0.0207 0.0207
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0219 0.0751 0.0751
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0085 0.0068 0.03
Loa Loa (eye worm) hypothetical protein 0.0118 0.0235 0.022
Brugia malayi phosphoinositide-dependent protein kinase I 0.0082 0.0053 0.003
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Brugia malayi Immunoglobulin domain containing protein 0.0112 0.0207 0.0184
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Loa Loa (eye worm) thioredoxin reductase 0.204 1 1
Schistosoma mansoni cell adhesion molecule 0.011 0.0197 0.0197
Echinococcus granulosus roundabout 2 0.0594 0.2653 0.2653
Echinococcus granulosus protein kinase 0.0152 0.0408 0.0408
Plasmodium vivax serine/threonine kinase-1, putative 0.0152 0.0411 0.0362
Trypanosoma brucei Casein kinase II 0.01 0.0145 0.0096
Brugia malayi Prion-like- 0.0095 0.012 0.0097
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Onchocerca volvulus Tyrosine kinase homolog 0.0447 0.1905 1
Entamoeba histolytica protein kinase, putative 0.0145 0.037 0.1623
Echinococcus granulosus cyclin dependent kinase 0.0118 0.0238 0.0238
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0197 0.0175
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0118 0.0238 0.0189
Onchocerca volvulus Putative titin 0.0095 0.012 0.0571
Plasmodium falciparum glutathione reductase 0.0707 0.3228 0.3194
Brugia malayi Protein kinase domain containing protein 0.0588 0.2624 0.2607
Echinococcus granulosus leucine rich repeat containing protein 4 0.0095 0.012 0.012
Schistosoma mansoni protein kinase 0.0086 0.0075 0.0075
Echinococcus granulosus titin 0.0095 0.012 0.012
Echinococcus granulosus Protein kinase C brain isozyme 0.0247 0.0892 0.0892
Entamoeba histolytica casein kinase, putative 0.0109 0.0188 0.0822
Brugia malayi Protein kinase domain containing protein 0.0361 0.1467 0.1448
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0128 0.0287 0.0239
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.069 0.0669
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0122 0.0255 0.0207
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0188 0.0589 0.0589
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0209 0.0209
Schistosoma mansoni basigin related 0.0112 0.0207 0.0207
Echinococcus multilocularis mitogen activated protein kinase 3 0.0084 0.0064 0.0064
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0084 0.0061 0.0012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.069 0.0669
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0095 0.012 0.012
Schistosoma mansoni serine/threonine protein kinase 0.0387 0.1603 0.1603
Onchocerca volvulus 0.0095 0.012 0.0571
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0219 0.0751 0.0737
Echinococcus granulosus neurogenic locus notch protein 0.0206 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0112 0.0207 0.0192
Schistosoma mansoni titin 0.0095 0.012 0.012
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0137 0.0331 0.0331
Echinococcus multilocularis C type lectin domian containing protein 0.0381 0.157 0.157
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.009 0.0092 0.0043
Brugia malayi Heparan sulfate 0.0112 0.0207 0.0184
Giardia lamblia Kinase, CAMK CAMKL 0.009 0.0092 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0186 0.0583 0.167
Echinococcus granulosus cGMP dependent protein kinase 1 0.0134 0.0316 0.0316
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0144 0.0367 0.0367
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0338 0.0338
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0188 0.0589 0.0568
Echinococcus granulosus epidermal growth factor receptor 0.0598 0.2675 0.2675
Echinococcus granulosus insulin growth factor binding 0.0095 0.012 0.012
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0588 0.2624 0.2613
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0086 0.0075 0.0075
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0188 0.0425
Echinococcus granulosus cGMP dependent protein kinase 0.0134 0.0316 0.0316
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0144 0.0367 0.0367
Entamoeba histolytica protein kinase, putative 0.0074 0.0012 0.0053
Brugia malayi Protein kinase domain containing protein 0.0214 0.0725 0.0703
Brugia malayi Variant SH3 domain containing protein 0.0094 0.0113 0.009
Giardia lamblia Kinase, NEK 0.0135 0.0324 0.0831
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.0238 0.0227
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0209 0.0194
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0209 0.0209
Giardia lamblia Kinase, CMGC GSK 0.0128 0.0287 0.0714
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0188 0.0188
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0109 0.019 0.019
Echinococcus granulosus mitogen activated protein kinase 14 0.0158 0.0438 0.0438
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0109 0.019 0.019
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0213 0.072 0.072
Loa Loa (eye worm) hypothetical protein 0.0371 0.1521 0.1509
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0266 0.0989 0.0975
Onchocerca volvulus 0.0381 0.157 0.8229
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Loa Loa (eye worm) hypothetical protein 0.0109 0.019 0.0175
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0109 0.0188 0.0176
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.0238 0.0227
Echinococcus granulosus protein jagged 1 0.0206 0.0683 0.0683
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0115 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.0226 0.0786 0.0772
Schistosoma mansoni cell adhesion molecule 0.011 0.0197 0.0197
Schistosoma mansoni hypothetical protein 0.0112 0.0207 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.0266 0.0989 0.0989
Loa Loa (eye worm) hypothetical protein 0.0349 0.141 0.1397
Loa Loa (eye worm) hypothetical protein 0.009 0.0094 0.0079
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.0238 0.0227
Echinococcus multilocularis mitogen activated protein kinase 14 0.0158 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0113 0.0209 0.0194
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0215 0.0215
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0707 0.3228 0.3228
Schistosoma mansoni sulfide quinone reductase 0.0188 0.0589 0.0589
Entamoeba histolytica serine/threonine protein kinase, putative 0.009 0.0092 0.0403
Loa Loa (eye worm) TK/FAK protein kinase 0.0547 0.2413 0.2402
Echinococcus multilocularis Immunoglobulin 0.0371 0.1521 0.1521
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0112 0.0207 0.0207
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0238 0.0583
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0899 0.0899
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0707 0.3228 0.3194
Plasmodium vivax protein kinase Crk2 0.0118 0.0238 0.0188
Loa Loa (eye worm) hypothetical protein 0.0135 0.0324 0.031
Echinococcus multilocularis c4b binding protein beta chain 0.0381 0.157 0.157
Schistosoma mansoni septate junction protein 0.0112 0.0207 0.0207
Toxoplasma gondii EGF family domain-containing protein 0.0206 0.0683 0.0637
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0209 0.0161
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Echinococcus granulosus casein kinase ii subunit alpha 0.01 0.0145 0.0145
Brugia malayi Protein kinase domain containing protein 0.009 0.0094 0.0071
Brugia malayi protein-tyrosine kinase 0.0186 0.0578 0.0557
Echinococcus multilocularis neurogenic locus protein delta 0.0206 0.0683 0.0683
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0121 0.0249 0.0249
Schistosoma mansoni septate junction protein 0.0112 0.0207 0.0207
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0215 0.051
Schistosoma mansoni tyrosine kinase 0.0308 0.1201 0.1201
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0513 0.2243 0.2243
Leishmania major casein kinase, putative 0.0109 0.0188 0.0139
Loa Loa (eye worm) SRC-1 0.0223 0.0768 0.0754
Trypanosoma brucei aurora B kinase 0.0145 0.037 0.0322
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0347 0.1397 0.1384
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.0238 0.1043
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0138 0.0338 0.029
Schistosoma mansoni nephrin related 0.0095 0.012 0.012
Schistosoma mansoni cell adhesion molecule 0.0223 0.0768 0.0768
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0188 0.0589 0.0543
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0188 0.0589 0.0543
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0218 0.0218
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0209 0.0209
Brugia malayi Calcium binding EGF domain containing protein 0.0206 0.0683 0.0662
Brugia malayi Muscle positioning protein 4 0.0206 0.0683 0.0662
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0209 0.0161
Echinococcus granulosus twitchin 0.0501 0.2181 0.2181
Echinococcus granulosus expressed protein 0.0084 0.0061 0.0061
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0122 0.0255 0.0207
Onchocerca volvulus 0.0095 0.012 0.0571
Plasmodium falciparum calcium-dependent protein kinase 2 0.0101 0.0149 0.01
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0188 0.0589 0.0589
Echinococcus multilocularis serine:threonine protein kinase 3 0.0253 0.0922 0.0922
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0207 0.069 0.069
Onchocerca volvulus 0.0381 0.157 0.8229
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0361 0.1467 0.1455
Echinococcus granulosus Glutaredoxin protein 5 0.0121 0.0249 0.0249
Echinococcus granulosus titin 0.0145 0.0373 0.0373
Brugia malayi Protein kinase domain containing protein 0.01 0.0142 0.012
Echinococcus multilocularis roundabout 2 0.0594 0.2653 0.2653
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0188 0.0589 0.1455
Onchocerca volvulus 0.0189 0.0596 0.3088
Onchocerca volvulus Peroxidasin homolog 0.0095 0.012 0.0571
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0215 0.0215
Toxoplasma gondii rhoptry neck protein RON1 0.0381 0.157 0.1528
Brugia malayi SH2 domain containing protein 0.0396 0.1647 0.1628
Schistosoma mansoni nephrin related 0.0112 0.0207 0.0207
Schistosoma mansoni protein kinase 0.01 0.0145 0.0145
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0113 0.0209 0.0161
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Trichomonas vaginalis glutathione reductase, putative 0.0707 0.3228 1
Schistosoma mansoni slit 0.0095 0.0121 0.0121
Plasmodium falciparum ferrodoxin reductase-like protein 0.0188 0.0589 0.0543
Brugia malayi RhoGAP domain containing protein 0.0094 0.0113 0.009
Schistosoma mansoni ste20-related kinase 0.0203 0.0666 0.0666
Echinococcus multilocularis rho associated protein kinase 0.032 0.1261 0.1261
Echinococcus multilocularis protein jagged 2 0.0206 0.0683 0.0683
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0835 0.3877 0.3868
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0068 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0095 0.012 0.0105
Brugia malayi serine/threonine protein kinase 6 0.0145 0.037 0.0348
Echinococcus multilocularis nervana 2 0.0121 0.0249 0.0249
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0112 0.0207 0.0207
Schistosoma mansoni disulfide oxidoreductase 0.0188 0.0589 0.0589
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0238 0.0583
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0381 0.157 0.1557
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0188 0.0589 0.169
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.0238 0.0223
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0266 0.0989 0.0989
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.3194
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Schistosoma mansoni growth factor receptor-bound protein 0.009 0.0094 0.0094
Echinococcus granulosus protein kinase c epsilon type 0.0208 0.0695 0.0695
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Brugia malayi hypothetical protein 0.01 0.0142 0.012
Loa Loa (eye worm) hypothetical protein 0.0207 0.069 0.0676
Plasmodium vivax glutathione reductase, putative 0.204 1 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0707 0.3228 0.3194
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0101 0.0149 0.0099
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0707 0.3228 1
Echinococcus multilocularis protein tyrosine kinase 0.0541 0.2383 0.2383
Toxoplasma gondii rhoptry neck protein RON9 0.0381 0.157 0.1528
Echinococcus granulosus titin 0.0095 0.012 0.012
Schistosoma mansoni hypothetical protein 0.0112 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0588 0.2624 0.2613
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0361 0.1467 0.1467
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0101 0.0149 0.0149
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0316 0.0316
Echinococcus multilocularis serine:threonine protein kinase N2 0.0127 0.0279 0.0279
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0707 0.3228 1
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Brugia malayi Leucine Rich Repeat family protein 0.0095 0.0121 0.0098
Loa Loa (eye worm) hypothetical protein 0.0349 0.141 0.1397
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Loa Loa (eye worm) one IG domain family member 0.0095 0.012 0.0105
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0128 0.0287 0.0276
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0188 0.0589 0.0575
Echinococcus multilocularis slit 2 protein 0.0234 0.0825 0.0825
Brugia malayi casein kinase 1, delta 0.0109 0.0188 0.0165
Schistosoma mansoni serine/threonine protein kinase 0.0694 0.3162 0.3162
Brugia malayi Protein kinase domain containing protein 0.0296 0.1139 0.1119
Loa Loa (eye worm) hypothetical protein 0.01 0.0142 0.0127
Schistosoma mansoni tyrosine kinase 0.0255 0.0932 0.0932
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Brugia malayi Protein kinase domain containing protein 0.0084 0.0061 0.0038
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0094 0.0113 0.0113
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0397 0.1654 0.1654
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0174 0.052 0.0506
Onchocerca volvulus 0.0109 0.0188 0.093
Giardia lamblia Kinase, CMGC CLK 0.0152 0.0411 0.1105
Echinococcus multilocularis N chimaerin 0.0094 0.0113 0.0113
Plasmodium vivax calcium-dependent protein kinase, putative 0.0101 0.0149 0.0099
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0188 0.0589 0.0589
Echinococcus granulosus dual specificity protein kinase clk2 0.0152 0.0411 0.0411
Schistosoma mansoni myosin-binding protein-related 0.011 0.0197 0.0197
Echinococcus multilocularis protein jagged 1 0.0206 0.0683 0.0683
Echinococcus multilocularis tyrosine protein kinase ABL1 0.01 0.0142 0.0142
Schistosoma mansoni hypothetical protein 0.0112 0.0207 0.0207
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0188 0.0589 0.1455
Brugia malayi Protein kinase domain containing protein 0.0588 0.2624 0.2607
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Loa Loa (eye worm) hypothetical protein 0.0483 0.2092 0.208
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0166 0.0481 0.0481
Plasmodium vivax glycogen synthase kinase 3, putative 0.0128 0.0287 0.0238
Brugia malayi Delta serrate ligand family protein 0.0206 0.0683 0.0662
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.026 0.0959 0.0946
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0152 0.0407 0.1115
Echinococcus granulosus contactin 0.0223 0.0768 0.0768
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0094 0.0113 0.0113
Trypanosoma cruzi polo-like protein kinase, putative 0.0266 0.0989 0.0979
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Plasmodium vivax serine/threonine protein kinase, putative 0.0084 0.0061 0.001
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Loa Loa (eye worm) hypothetical protein 0.0112 0.0207 0.0192
Loa Loa (eye worm) hypothetical protein 0.0207 0.069 0.0676
Echinococcus multilocularis transfer RNA-Phe 0.011 0.0197 0.0197
Leishmania major hypothetical protein, conserved 0.0188 0.0589 0.0543
Loa Loa (eye worm) hypothetical protein 0.0112 0.0207 0.0192
Mycobacterium tuberculosis Probable oxidoreductase 0.0707 0.3228 0.2803
Entamoeba histolytica cyclin C, putative 0.0521 0.2281 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0707 0.3228 1
Echinococcus granulosus casein kinase I alpha 0.0109 0.0188 0.0188
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0092 0.0043
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0082 0.005 0.0001
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0188 0.0589 0.0589
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.035 0.0328
Echinococcus multilocularis cyclin dependent kinase 5 0.0118 0.0238 0.0238
Schistosoma mansoni hypothetical protein 0.0112 0.0207 0.0207
Schistosoma mansoni ephrin receptor 0.0109 0.0191 0.0191
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.037 0.037
Echinococcus granulosus tyrosine protein kinase Src64B 0.0223 0.0768 0.0768
Echinococcus multilocularis insulin growth factor binding 0.0095 0.012 0.012
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0068 0.0057
Onchocerca volvulus 0.0095 0.012 0.0571
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.02 0.0653 0.0639
Giardia lamblia Glutamate synthase 0.0188 0.0589 0.1669
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Onchocerca volvulus 0.0285 0.1085 0.5669
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0188 0.0589 0.0579
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0095 0.012 0.0105
Schistosoma mansoni protein kinase 0.0233 0.082 0.082
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0064 0.0035
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0166 0.0481 0.0481
Leishmania major protein kinase, putative 0.0152 0.0411 0.0363
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0207 0.0184
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0481 0.135
Brugia malayi hypothetical protein 0.0112 0.0207 0.0184
Echinococcus multilocularis rac serine:threonine kinase 0.0164 0.047 0.047
Onchocerca volvulus 0.0095 0.012 0.0571
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0188 0.0425
Trichomonas vaginalis AGC family protein kinase 0.0195 0.0627 0.1809
Echinococcus granulosus Immunoglobulin 0.0112 0.0207 0.0207
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0188 0.0589 0.0589
Brugia malayi Cam kinase protein 1 0.0101 0.0149 0.0126
Onchocerca volvulus 0.0188 0.0589 0.3052
Echinococcus granulosus nephrin 0.011 0.0197 0.0197
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0247 0.0892 0.0892
Plasmodium falciparum protein kinase 5 0.0118 0.0238 0.0189
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Entamoeba histolytica protein kinase, putative 0.0084 0.0061 0.0267
Loa Loa (eye worm) CAMK protein kinase 0.0145 0.0373 0.0359
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Onchocerca volvulus 0.0381 0.157 0.8229
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0149 0.0149
Echinococcus multilocularis casein kinase ii subunit alpha 0.01 0.0145 0.0145
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0112 0.0207 0.0207
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0109 0.019 0.019
Brugia malayi Cadherin domain containing protein 0.0206 0.0683 0.0662
Loa Loa (eye worm) programmed cell death 8 0.0188 0.0589 0.0575
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0113 0.0209 0.0161
Echinococcus granulosus raf serine:threonine protein kinase 0.0088 0.0081 0.0081
Onchocerca volvulus 0.0095 0.012 0.0571
Giardia lamblia Kinase, STE STE20 0.0085 0.0068 0.0024
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0249 0.0899 0.0899
Giardia lamblia Kinase, CDC7 0.009 0.0094 0.0104
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0197 0.0175
Giardia lamblia High cysteine protein 0.0206 0.0683 0.1966
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Schistosoma mansoni hypothetical protein 0.0188 0.0589 0.0589
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0223 0.0768 0.0768
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0188 0.0589 0.0568
Plasmodium falciparum serine/threonine protein kinase KIN 0.009 0.0092 0.0043
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0188 0.0188
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Echinococcus multilocularis tyrosine kinase 0.01 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Echinococcus granulosus aurora kinase A 0.0145 0.037 0.037
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0213 0.072 0.072
Trypanosoma cruzi hypothetical protein, conserved 0.0188 0.0589 0.0579
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0118 0.0238 0.0189
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Echinococcus granulosus tyrosine protein kinase Src42A 0.0223 0.0768 0.0768
Schistosoma mansoni protein kinase 0.0109 0.0188 0.0188
Schistosoma mansoni titin 0.0095 0.012 0.012
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0152 0.0411 0.0363
Trypanosoma cruzi casein kinase, putative 0.0109 0.0188 0.0176
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0184 0.057 0.057
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0158 0.0438 0.0423
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0145 0.037 0.1623
Echinococcus multilocularis Immunoglobulin 0.0371 0.1521 0.1521
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0208 0.0695 0.0681
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0112 0.0207 0.0207
Schistosoma mansoni atypical protein kinase C 0.0294 0.113 0.113
Trypanosoma cruzi Protein kinase B 0.0164 0.047 0.0459
Mycobacterium ulcerans glutamate synthase subunit beta 0.0188 0.0589 0.1455
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0134 0.0316 0.0268
Brugia malayi Protein kinase domain containing protein 0.0118 0.0238 0.0215
Schistosoma mansoni nephrin 0.0482 0.2082 0.2082
Echinococcus granulosus ephrin type A receptor 4 A 0.0109 0.0191 0.0191
Trichomonas vaginalis AGC family protein kinase 0.0145 0.037 0.1
Schistosoma mansoni cell adhesion molecule 0.0112 0.0207 0.0207
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0188 0.0589 0.0543
Schistosoma mansoni serine/threonine protein kinase 0.026 0.0959 0.0959
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0219 0.0525
Echinococcus granulosus casein kinase I gamma 0.0211 0.0706 0.0706
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0266 0.0989 0.0989
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0208 0.0186
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0707 0.3228 0.3212
Schistosoma mansoni protein kinase 0.0145 0.037 0.037
Echinococcus granulosus serine:threonine protein kinase N2 0.0293 0.1124 0.1124
Schistosoma mansoni slit 0.0206 0.0685 0.0685
Entamoeba histolytica protein kinase domain containing protein 0.0128 0.0287 0.1257
Schistosoma mansoni neuroglian 0.0223 0.0768 0.0768
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.069 0.0669
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0232 0.0814 0.0814
Schistosoma mansoni hemicentin 0.011 0.0197 0.0197
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0188 0.0589 0.169
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0197 0.0175
Schistosoma mansoni septate junction protein 0.0207 0.069 0.069
Trypanosoma brucei hypothetical protein, conserved 0.0188 0.0589 0.0543
Brugia malayi SRC-1 0.0223 0.0768 0.0746
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0061 0.0049
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0188 0.0589 0.0542
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0145 0.037 0.1623
Plasmodium falciparum calcium-dependent protein kinase 5 0.0101 0.0149 0.01
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.3194
Entamoeba histolytica thioredoxin reductase, putative 0.0188 0.0589 0.2584
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0112 0.0207 0.0207
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0155 0.0425 0.0378
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Onchocerca volvulus 0.0095 0.012 0.0571
Brugia malayi P38 map kinase family protein 2 0.0158 0.0438 0.0416
Brugia malayi C1-like domain containing protein 0.0215 0.0728 0.0707
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0223 0.0768 0.0768
Onchocerca volvulus 0.0206 0.0683 0.3548
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0092 0.0081
Schistosoma mansoni tyrosine kinase 0.0395 0.1643 0.1643
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Brugia malayi glutamate synthase 0.0188 0.0589 0.0568
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0198 0.0644 0.063
Echinococcus granulosus neuroglian 0.0223 0.0768 0.0768
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0081 0.0049 0.0038
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0707 0.3228 0.2803
Schistosoma mansoni hypothetical protein 0.0095 0.012 0.012
Leishmania major hypothetical protein, conserved 0.0188 0.0589 0.0543
Loa Loa (eye worm) hypothetical protein 0.0176 0.0532 0.0517
Trypanosoma brucei polo-like protein kinase 0.0266 0.0989 0.0944
Schistosoma mansoni titin 0.011 0.0197 0.0197
Echinococcus granulosus thioredoxin glutathione reductase 0.204 1 1
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0082 0.005 0.0001
Echinococcus multilocularis protein kinase shaggy 0.0128 0.0287 0.0287
Echinococcus granulosus serine threonine protein kinase nrc 0.0155 0.0425 0.0425
Brugia malayi Tyrosine-protein kinase abl-1 0.0137 0.0331 0.0309
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0188 0.0589 0.169
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0092 0.0092
Entamoeba histolytica SH2-protein kinase domain containing protein 0.01 0.0142 0.0624
Loa Loa (eye worm) hypothetical protein 0.0234 0.0825 0.0811
Echinococcus multilocularis death associated protein kinase 1 0.0831 0.3856 0.3856
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0121 0.0249 0.0249
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0347 0.1397 0.1377
Brugia malayi EGF-like domain containing protein 0.0206 0.0683 0.0662
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Echinococcus granulosus fibroblast growth factor receptor 4 0.024 0.0856 0.0856
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0462 0.0462
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0325 0.1288 0.1268
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0094 0.0129
Echinococcus granulosus slit 2 protein 0.0234 0.0825 0.0825
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0086 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.011 0.0197 0.0197
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0109 0.019 0.0179
Onchocerca volvulus 0.0381 0.157 0.8229
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0134 0.0316 0.0316
Echinococcus multilocularis neurogenic locus notch protein 4 0.0206 0.0683 0.0683
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0152 0.0411 0.04
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0149 0.0149
Schistosoma mansoni hypothetical protein 0.0109 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0139 0.0344 0.033
Onchocerca volvulus Peroxidasin homolog 0.0095 0.0121 0.0579
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0338 0.0898
Echinococcus granulosus dual specificity 0.0122 0.0255 0.0255
Echinococcus granulosus serine:threonine kinase SAD 1 0.009 0.0092 0.0092
Brugia malayi Immunoglobulin I-set domain containing protein 0.0223 0.0768 0.0747
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0112 0.0207 0.0207
Echinococcus granulosus neurogenic locus notch protein 0.0206 0.0683 0.0683
Onchocerca volvulus 0.0139 0.0344 0.1759
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0061 0.0012
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0117 0.0229 0.0207
Schistosoma mansoni protein kinase 0.0426 0.18 0.18
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0186 0.0578 0.0578
Echinococcus granulosus NCK adaptor protein 0.009 0.0094 0.0094
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0188 0.0589 0.0579
Onchocerca volvulus 0.018 0.0552 0.2854
Brugia malayi Protein kinase domain containing protein 0.0922 0.432 0.4307
Loa Loa (eye worm) hypothetical protein 0.0135 0.0324 0.031
Echinococcus granulosus low density lipoprotein receptor ldl 0.0112 0.0207 0.0207
Brugia malayi Immunoglobulin I-set domain containing protein 0.0223 0.0768 0.0747
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0092 0.0092
Echinococcus granulosus delta-like protein 1 0.0206 0.0683 0.0683
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0188 0.0589 0.0589
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0387 0.1603 0.1591
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0134 0.0316 0.0316
Toxoplasma gondii casein kinase I 0.0109 0.0188 0.0139
Brugia malayi Protein kinase domain containing protein 0.0191 0.0605 0.0583
Entamoeba histolytica protein kinase, putative 0.0296 0.1139 0.4994
Schistosoma mansoni roundabout 0.0207 0.069 0.069
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Loa Loa (eye worm) TK protein kinase 0.0186 0.0578 0.0564
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Schistosoma mansoni peroxidasin 0.0113 0.0208 0.0208
Schistosoma mansoni glutamate synthase 0.0188 0.0589 0.0589
Brugia malayi Stress-activated protein kinase jnk-1 0.026 0.0959 0.0938
Plasmodium falciparum thioredoxin reductase 0.204 1 1
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Schistosoma mansoni sulfide quinone reductase 0.0188 0.0589 0.0589
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0128 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Echinococcus multilocularis tyrosine protein kinase otk 0.0207 0.069 0.069
Echinococcus granulosus Immunoglobulin subtype 0.0112 0.0207 0.0207
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0223 0.0768 0.0768
Loa Loa (eye worm) LAD-2 short isoform 0.0112 0.0207 0.0192
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0215 0.0215
Brugia malayi Protein kinase c protein 2 0.0115 0.0222 0.02
Echinococcus multilocularis tyrosine protein kinase Srms 0.0186 0.0578 0.0578
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0347 0.1397 0.7317
Echinococcus granulosus tyrosine protein kinase Blk 0.0186 0.0578 0.0578
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Trypanosoma cruzi hypothetical protein, conserved 0.0188 0.0589 0.0579
Onchocerca volvulus 0.01 0.0142 0.0691
Brugia malayi Protein kinase domain containing protein 0.0278 0.1046 0.1026
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.009 0.0094 0.0094
Giardia lamblia Kinase, CMGC GSK 0.0128 0.0287 0.0714
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Trypanosoma cruzi casein kinase, putative 0.0109 0.0188 0.0176
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0513 0.2243 0.2243
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0188 0.0589 0.169
Echinococcus multilocularis mitogen activated protein kinase 11 0.0158 0.0438 0.0438
Echinococcus multilocularis titin 0.0095 0.012 0.012
Onchocerca volvulus 0.0381 0.157 0.8229
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.322
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0145 0.037 0.037
Giardia lamblia Kinase, CMGC CDK 0.0118 0.0238 0.0559
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.1397 0.1397
Brugia malayi Protein kinase domain containing protein 0.0192 0.0609 0.0588
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Onchocerca volvulus 0.009 0.0094 0.0436
Schistosoma mansoni basigin related 0.0112 0.0207 0.0207
Schistosoma mansoni notch 0.0206 0.0683 0.0683
Echinococcus granulosus insulin receptor 0.044 0.1869 0.1869
Echinococcus granulosus netrin receptor unc 5 0.0141 0.035 0.035
Echinococcus granulosus titin 0.0095 0.012 0.012
Leishmania major protein kinase, putative 0.0152 0.0411 0.0363
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0387 0.1603 0.1603
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0233 0.082 0.082
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0188 0.0589 0.2584
Loa Loa (eye worm) hypothetical protein 0.0234 0.0825 0.0811
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0188 0.0589 0.1455
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0215 0.0728 0.0714
Trypanosoma cruzi trypanothione reductase, putative 0.204 1 1
Echinococcus multilocularis neuroglian 0.0223 0.0768 0.0768
Echinococcus granulosus protein kinase c iota type 0.0288 0.11 0.11
Onchocerca volvulus 0.0305 0.1185 0.6195
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0209 0.0187
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0188 0.0589 0.2584
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0219 0.0525
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0094 0.0094
Plasmodium falciparum serine/threonine protein kinase 0.0084 0.0061 0.0012
Onchocerca volvulus 0.0145 0.0373 0.1911
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0163 0.0462 0.0448
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0213 0.072 0.072
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0707 0.3228 0.3193
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0223 0.0768 0.0768
Brugia malayi Calcium binding EGF domain containing protein 0.0206 0.0683 0.0662
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0166 0.0481 0.0481
Trypanosoma brucei cdc2-related kinase 3 0.0118 0.0238 0.0189
Echinococcus granulosus cGMP dependent protein kinase 1 0.0134 0.0316 0.0316
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0149 0.0302
Onchocerca volvulus 0.0206 0.0683 0.3548
Trichomonas vaginalis CMGC family protein kinase 0.0152 0.0411 0.1127
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0188 0.0589 0.0543
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0128 0.0284 0.0284
Entamoeba histolytica protein kinase 2, putative 0.0155 0.0425 0.1865
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.0814 0.0814
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0101 0.0149 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0913 0.0913
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0084 0.0064 0.0015
Echinococcus granulosus serine:threonine protein kinase N2 0.0127 0.0279 0.0279
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0149 0.0149
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0188 0.0589 0.2584
Onchocerca volvulus 0.0381 0.157 0.8229
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.0814 0.0814
Echinococcus granulosus C type lectin domian containing protein 0.0381 0.157 0.157
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0158 0.0438 0.039
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0188 0.0589 0.1455
Loa Loa (eye worm) hypothetical protein 0.045 0.1924 0.1912
Echinococcus multilocularis c Jun NH2 terminal kinase 0.026 0.0959 0.0959
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0138 0.0338 0.029
Entamoeba histolytica disulphide oxidoreductase, putative 0.0188 0.0589 0.2584
Entamoeba histolytica casein kinase, putative 0.01 0.0145 0.0636
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0101 0.0149 0.0134
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0707 0.3228 1
Brugia malayi hypothetical protein 0.0219 0.0751 0.0729
Echinococcus granulosus epidermal growth factor receptor 0.0395 0.1643 0.1643
Loa Loa (eye worm) AUR protein kinase 0.0145 0.037 0.0356
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0397 0.1654 0.1654
Brugia malayi Thioredoxin reductase 0.204 1 1
Echinococcus granulosus rho-associated protein kinase 1 0.032 0.1261 0.1261
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0266 0.0989 0.0944
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0197 0.0175
Trypanosoma brucei NADH dehydrogenase 0.0188 0.0589 0.0543
Schistosoma mansoni cell adhesion molecule 0.0223 0.0768 0.0768
Entamoeba histolytica PH domain containing protein kinase, putative 0.0122 0.0254 0.1112
Leishmania major protein kinase, putative 0.0145 0.037 0.0322
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0053 0.0053
Schistosoma mansoni cell adhesion molecule 0.0112 0.0207 0.0207
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0112 0.0207 0.0192
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Schistosoma mansoni serine/threonine-protein kinase 0.0164 0.047 0.047
Loa Loa (eye worm) casein kinase 0.0176 0.053 0.0516
Trichomonas vaginalis STE family protein kinase 0.0086 0.0075 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0293 0.1124 0.1124
Echinococcus multilocularis casein kinase I delta 0.0109 0.0188 0.0188
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0101 0.0149 0.01
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0064 0.0035
Echinococcus granulosus fibropellin Ia 0.0206 0.0683 0.0683
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0483 0.2092 0.2092
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0122 0.0255 0.024
Onchocerca volvulus 0.011 0.0197 0.0981
Echinococcus multilocularis dual specificity 0.0138 0.0338 0.0338
Echinococcus granulosus hypothetical protein 0.0118 0.0235 0.0235
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0485 0.21 0.21
Schistosoma mansoni tyrosine kinase 0.0348 0.1406 0.1406
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0207 0.069 0.0676
Echinococcus granulosus casein kinase I delta 0.0109 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Entamoeba histolytica protein kinase, putative 0.0102 0.0155 0.068
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0152 0.0411 0.0396
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0138 0.0338 0.0323
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Loa Loa (eye worm) TK/EPH protein kinase 0.0126 0.0278 0.0263
Brugia malayi Immunoglobulin I-set domain containing protein 0.0835 0.3877 0.3863
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0188 0.0589 0.169
Brugia malayi Temporarily assigned gene name protein 59 0.0126 0.0276 0.0254
Entamoeba histolytica protein kinase, putative 0.0145 0.037 0.1623
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0128 0.0284 0.0284
Brugia malayi GCC2 and GCC3 family protein 0.0587 0.2617 0.26
Schistosoma mansoni c4b-binding protein beta chain 0.0381 0.157 0.157
Giardia lamblia Kinase, CK1 Casein kinase 0.0109 0.0188 0.04
Loa Loa (eye worm) hypothetical protein 0.0207 0.069 0.0676
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0112 0.0207 0.0207
Onchocerca volvulus 0.01 0.0142 0.0691
Brugia malayi Doublecortin family protein 0.015 0.0397 0.0375
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0892 0.0892
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0082 0.0053 0.0053
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0707 0.3228 1
Onchocerca volvulus 0.0381 0.157 0.8229
Echinococcus multilocularis tyrosine protein kinase Blk 0.0186 0.0578 0.0578
Loa Loa (eye worm) hypothetical protein 0.0587 0.2617 0.2606
Loa Loa (eye worm) sex muscle abnormal protein 5 0.009 0.0094 0.0079
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0188 0.0589 0.1455
Schistosoma mansoni tyrosine kinase 0.024 0.0856 0.0856
Echinococcus granulosus growth factor receptor bound protein 2 0.0092 0.0104 0.0104
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0338 0.0898
Brugia malayi EGF-like domain containing protein 0.0234 0.0825 0.0804
Brugia malayi Prion-like- 0.0095 0.012 0.0097
Brugia malayi Prion-like- 0.0207 0.069 0.0669
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Leishmania major NADH dehydrogenase, putative 0.0188 0.0589 0.0543
Brugia malayi Homeodomain interacting protein kinase protein 1 0.02 0.0653 0.0632
Leishmania major trypanothione reductase 0.204 1 1
Trypanosoma brucei casein kinase I, isoform 2 0.0109 0.0188 0.0139
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0481 0.0481
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0101 0.0149 0.0099
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0338 0.0898
Echinococcus granulosus serine/threonine protein kinase 0.0164 0.047 0.047
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0078 0.0033 0.0033
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0455 0.1947 0.1947
Onchocerca volvulus 0.0381 0.157 0.8229
Trypanosoma cruzi polo-like protein kinase, putative 0.0266 0.0989 0.0979
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0084 0.0064 0.0052
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0707 0.3228 0.322
Echinococcus multilocularis glutamate synthase 0.0188 0.0589 0.0589
Brugia malayi notch-like transmembrane receptor 0.0206 0.0683 0.0662
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0922 0.432 0.4311
Trypanosoma cruzi casein kinase, putative 0.0109 0.0188 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0317 0.0317
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0101 0.0149 0.0099
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Loa Loa (eye worm) hypothetical protein 0.0109 0.019 0.0175
Brugia malayi Protein kinase domain containing protein 0.01 0.0142 0.012
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0184 0.057 0.0556
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0361 0.1467 0.1467
Echinococcus granulosus hemicentin 1 0.0207 0.069 0.069
Echinococcus multilocularis ephrin type A receptor 4 A 0.0109 0.0191 0.0191
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Giardia lamblia Kinase, AGC AKT 0.0117 0.0229 0.0532
Brugia malayi Temporarily assigned gene name protein 59 0.0109 0.019 0.0168
Schistosoma mansoni hypothetical protein 0.0095 0.012 0.012
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0086 0.0075 0.0075
Echinococcus granulosus NDR protein kinase 0.0166 0.0481 0.0481
Plasmodium falciparum thioredoxin reductase 0.0707 0.3228 0.3194
Plasmodium falciparum cGMP-dependent protein kinase 0.0134 0.0316 0.0268
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0128 0.0287 0.0272
Echinococcus granulosus tyrosine protein kinase Lyn 0.0257 0.0944 0.0944
Trichomonas vaginalis STE family protein kinase 0.0085 0.0068 0.005
Loa Loa (eye worm) hypothetical protein 0.0114 0.0215 0.02
Entamoeba histolytica protein kinase, putative 0.0166 0.0481 0.2111
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Schistosoma mansoni vesicular amine transporter 0.0371 0.1521 0.1521
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.011 0.0197 0.0182
Brugia malayi Protein kinase domain containing protein 0.044 0.1869 0.185
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0347 0.1397 0.1384
Echinococcus multilocularis expressed protein 0.0084 0.0061 0.0061
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Schistosoma mansoni nephrin 0.0223 0.0768 0.0768
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0223 0.0768 0.0768
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Brugia malayi Casein kinase II, alpha chain 0.01 0.0145 0.0123
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0223 0.0768 0.0768
Schistosoma mansoni protein kinase 0.0426 0.18 0.18
Brugia malayi Protein kinase domain containing protein 0.01 0.0142 0.012
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0317 0.0317
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0371 0.1521 0.1521
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.011 0.0197 0.0182
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0138 0.0338 0.029
Loa Loa (eye worm) hypothetical protein 0.0116 0.0226 0.0211
Echinococcus multilocularis tyrosine protein kinase HCK 0.0133 0.0309 0.0309
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0164 0.047 0.0459
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.072 0.072
Schistosoma mansoni tyrosine kinase 0.0362 0.1475 0.1475
Loa Loa (eye worm) TK/INSR protein kinase 0.044 0.1869 0.1857
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0287 0.0737
Schistosoma mansoni protein kinase C mu 0.0215 0.0728 0.0728
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0207 0.0184
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0707 0.3228 0.3194
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0188 0.0589 0.0589
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0128 0.0287 0.0287
Echinococcus multilocularis expressed conserved protein 0.0134 0.0316 0.0316
Entamoeba histolytica protein kinase domain containing protein 0.0122 0.0255 0.1117
Echinococcus granulosus protein kinase shaggy 0.0128 0.0287 0.0287
Echinococcus granulosus down syndrome cell adhesion 0.0095 0.012 0.012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0284 0.0262
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0112 0.0207 0.0207
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0188 0.0589 0.169
Loa Loa (eye worm) variant SH3 domain-containing protein 0.009 0.0094 0.0079
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0084 0.0064 0.0052
Trypanosoma cruzi casein kinase II, putative 0.01 0.0145 0.0134
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0064 0.0035
Brugia malayi Variant SH3 domain containing protein 0.009 0.0094 0.0072
Trichomonas vaginalis AGC family protein kinase 0.0145 0.037 0.1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0253 0.0922 0.0909
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0186 0.0583 0.0569
Mycobacterium ulcerans NADH dehydrogenase 0.0188 0.0589 0.1455
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.0644 0.0644
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0338 0.0898
Echinococcus granulosus serine:threonine protein kinase 3 0.0253 0.0922 0.0922
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0085 0.0068 0.0019
Schistosoma mansoni cell polarity protein 0.0206 0.0683 0.0683
Entamoeba histolytica serine/threonine protein kinase, putative 0.0266 0.0989 0.4336
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0223 0.0768 0.0754
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0411 0.0411
Trypanosoma brucei trypanothione reductase 0.204 1 1
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0188 0.0589 0.1455
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0086 0.0075 0.0075
Schistosoma mansoni netrin receptor unc5 0.0112 0.0207 0.0207
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0188 0.0589 0.169
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0152 0.0408 0.0394
Plasmodium falciparum casein kinase 2, alpha subunit 0.01 0.0145 0.0096
Brugia malayi putative serine/threonine kinase SADA gamma 0.009 0.0092 0.0069
Brugia malayi Protein kinase domain containing protein 0.01 0.0142 0.012
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0149 0.0149
Echinococcus multilocularis fibropellin Ia 0.0206 0.0683 0.0683
Echinococcus multilocularis fibroblast growth factor receptor 4 0.024 0.0856 0.0856
Brugia malayi Protein kinase domain containing protein 0.0152 0.0411 0.0389
Entamoeba histolytica protein kinase, putative 0.0082 0.0053 0.0231
Toxoplasma gondii CMGC kinase, CK2 family 0.01 0.0145 0.0096
Giardia lamblia Kinase, NEK 0.0135 0.0324 0.0831
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0219 0.0751 0.0751
Schistosoma mansoni hypothetical protein 0.0095 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0112 0.0207 0.0192
Echinococcus multilocularis casein kinase I delta 0.0109 0.0188 0.0188
Loa Loa (eye worm) thyroid receptor interactor 0.0111 0.0202 0.0187
Brugia malayi basement membrane proteoglycan precursor 0.0112 0.0207 0.0184
Entamoeba histolytica protein kinase domain containing protein 0.0081 0.0049 0.0216
Brugia malayi hypothetical protein 0.0386 0.1599 0.158
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0255 0.0255
Plasmodium falciparum calcium-dependent protein kinase 1 0.0101 0.0149 0.01
Trypanosoma cruzi casein kinase, putative 0.0109 0.0188 0.0176
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0707 0.3228 0.3194
Onchocerca volvulus 0.0109 0.019 0.0945
Leishmania major protein kinase A catalytic subunit 0.0113 0.0209 0.0161
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.0053 0.0038
Loa Loa (eye worm) animal heme peroxidase 0.0095 0.012 0.0105
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0707 0.3228 0.3193
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0188 0.0589 0.0579
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0095 0.012 0.0097
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0209 0.0198
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0223 0.0768 0.0768
Loa Loa (eye worm) hypothetical protein 0.0207 0.069 0.0676
Echinococcus multilocularis hypothetical protein 0.0099 0.0141 0.0141
Echinococcus granulosus tyrosine protein kinase Fyn 0.0223 0.0768 0.0768
Entamoeba histolytica protein kinase, putative 0.0287 0.1095 0.48
Brugia malayi Fibronectin type III domain containing protein 0.0386 0.1599 0.158
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0191 0.0605 0.0591
Echinococcus multilocularis serine:threonine kinase SAD 1 0.009 0.0092 0.0092
Echinococcus granulosus neurogenic locus notch protein 4 0.0206 0.0683 0.0683
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0207 0.069 0.0676
Schistosoma mansoni titin 0.0207 0.069 0.069
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0152 0.0411 0.04
Echinococcus granulosus tyrosine protein kinase Fyn 0.0223 0.0768 0.0768
Echinococcus granulosus tyrosine kinase 0.01 0.0142 0.0142
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.0238 0.0223
Echinococcus multilocularis Glutaredoxin protein 5 0.0121 0.0249 0.0249
Plasmodium falciparum calcium-dependent protein kinase 3 0.0101 0.0149 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0411 0.0411
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0455 0.1947 0.1947
Echinococcus granulosus tyrosine protein kinase Src42A 0.0141 0.0351 0.0351
Plasmodium vivax casein kinase 1, putative 0.0109 0.0188 0.0138
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0086 0.0075 0.0075
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0215 0.0215
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Mycobacterium ulcerans dehydrogenase 0.0188 0.0589 0.1455
Schistosoma mansoni protein kinase 0.0152 0.0408 0.0408
Onchocerca volvulus 0.0381 0.157 0.8229
Echinococcus granulosus protein jagged 1 0.0206 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0203 0.0668 0.0654
Echinococcus multilocularis neurogenic locus notch protein 0.0206 0.0683 0.0683
Echinococcus granulosus tyrosine protein kinase otk 0.0207 0.069 0.069
Loa Loa (eye worm) projectin 0.011 0.0197 0.0182
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0128 0.0287 0.0287
Onchocerca volvulus 0.0074 0.0011 0.0001
Trypanosoma brucei protein kinase, putative 0.0084 0.0064 0.0015
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0215 0.0728 0.0707
Echinococcus multilocularis Immunoglobulin 0.0112 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Trichomonas vaginalis CAMK family protein kinase 0.0126 0.0275 0.0701
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0086 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0087 0.0079 0.0064
Brugia malayi Variant SH3 domain containing protein 0.009 0.0094 0.0072
Schistosoma mansoni notch 0.0206 0.0683 0.0683
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0371 0.1521 0.1521
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0387 0.1603 0.1603
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0109 0.019 0.0142
Onchocerca volvulus 0.011 0.0197 0.0981
Loa Loa (eye worm) AUR protein kinase 0.0145 0.037 0.0356
Echinococcus multilocularis NCK adaptor protein 0.0092 0.0104 0.0104
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0287 0.0737
Brugia malayi EGF-like domain containing protein 0.0206 0.0683 0.0662
Echinococcus multilocularis netrin receptor unc 5 0.0141 0.035 0.035
Brugia malayi casein kinase I 0.0109 0.0188 0.0165
Leishmania major hypothetical protein, conserved 0.0188 0.0589 0.0543
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0209 0.016
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0426 0.18 0.18
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0152 0.0411 0.04
Echinococcus granulosus casein kinase I alpha 0.0109 0.0188 0.0188
Brugia malayi Sushi domain 0.0381 0.157 0.155
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0373 0.0373
Giardia lamblia Kinase, PLK 0.0266 0.0989 0.2931
Schistosoma mansoni hypothetical protein 0.0095 0.012 0.012
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0109 0.0188 0.0173
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0084 0.0061 0.0012
Echinococcus multilocularis raf serine:threonine protein kinase 0.0088 0.0081 0.0081
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0109 0.0188 0.0173
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0064 0.0064
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0188 0.0589 0.0543
Schistosoma mansoni vav2 0.0103 0.0157 0.0157
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0101 0.0149 0.0126
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0188 0.0589 0.2584
Trichomonas vaginalis apoptosis inducing factor, putative 0.0188 0.0589 0.169
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0144 0.0366 0.0366
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0128 0.0287 0.0239
Treponema pallidum NADH oxidase 0.0707 0.3228 1
Trypanosoma cruzi NADH dehydrogenase, putative 0.0188 0.0589 0.0579
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0481 0.0481
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0707 0.3228 0.2803
Schistosoma mansoni septate junction protein 0.0206 0.0683 0.0683
Trypanosoma cruzi trypanothione reductase, putative 0.0707 0.3228 0.322
Echinococcus granulosus neuroglian 0.0466 0.2005 0.2005
Brugia malayi Immunoglobulin domain containing protein 0.0112 0.0207 0.0184
Schistosoma mansoni rap gtpase-activating protein 0.0109 0.019 0.019
Echinococcus multilocularis serine threonine protein kinase 0.0206 0.0684 0.0684
Loa Loa (eye worm) Notch2 0.0206 0.0683 0.0669
Schistosoma mansoni serine/threonine protein kinase 0.013 0.0296 0.0296
Echinococcus multilocularis growth factor receptor bound protein 2 0.009 0.0094 0.0094
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0188 0.0589 0.0542
Toxoplasma gondii AGC kinase 0.0113 0.0209 0.0161
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0142 0.0357 0.0357
Echinococcus multilocularis titin 0.0095 0.012 0.012
Echinococcus granulosus roundabout 2 0.0223 0.0768 0.0768
Brugia malayi Protein kinase domain containing protein 0.0163 0.0462 0.0441
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.0238 0.1043
Echinococcus granulosus c4b binding protein beta chain 0.0381 0.157 0.157
Brugia malayi Myb-like DNA-binding domain containing protein 0.0095 0.012 0.0097
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0115 0.0219 0.0219
Brugia malayi Protein kinase domain containing protein 0.0166 0.0481 0.046
Echinococcus granulosus nervana 2 0.0121 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Schistosoma mansoni tyrosine kinase 0.0598 0.2675 0.2675
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.01 0.0145 0.0095
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0064 0.0035
Echinococcus multilocularis serine:threonine protein kinase 38 0.0166 0.0481 0.0481
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0101 0.0149 0.01
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.01 0.0145 0.013
Echinococcus granulosus homeodomain interacting protein kinase 3 0.02 0.0653 0.0653
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0707 0.3228 0.322
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.0238 0.0238
Entamoeba histolytica protein kinase, putative 0.0084 0.0061 0.0267
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0152 0.0411 0.04
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0101 0.0149 0.0134
Brugia malayi Fes/CIP4 homology domain containing protein 0.0111 0.0202 0.0179
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Echinococcus multilocularis epidermal growth factor receptor 0.0598 0.2675 0.2675
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Entamoeba histolytica protein kinase, putative 0.0296 0.1139 0.4994
Echinococcus granulosus roundabout 2 0.0223 0.0768 0.0768
Loa Loa (eye worm) hypothetical protein 0.0087 0.0079 0.0064
Schistosoma mansoni protein kinase 0.0261 0.0962 0.0962
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0188 0.0589 0.0543
Brugia malayi Protein kinase domain containing protein 0.044 0.1873 0.1854
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.069 0.0669
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0188 0.0589 0.0589
Trichomonas vaginalis STE family protein kinase 0.0086 0.0075 0.0071
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.0238 0.0227
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0519 0.2274 0.2257
Schistosoma mansoni tyrosine kinase 0.0348 0.1406 0.1406
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0109 0.019 0.019
Giardia lamblia NADH oxidase lateral transfer candidate 0.0707 0.3228 1
Schistosoma mansoni protein kinase 0.0233 0.082 0.082
Trypanosoma cruzi NADH dehydrogenase, putative 0.0188 0.0589 0.0579
Leishmania major protein kinase, putative 0.0101 0.0149 0.01
Schistosoma mansoni notch 0.0206 0.0683 0.0683
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0128 0.0287 0.0272
Onchocerca volvulus 0.0095 0.012 0.0571
Entamoeba histolytica protein kinase, putative 0.0088 0.0081 0.0356
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0395 0.1643 0.1643
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0155 0.0425 0.0425
Brugia malayi serine/threonine-protein kinase 6 0.0145 0.037 0.0348
Echinococcus multilocularis mitogen activated protein kinase 0.0084 0.0064 0.0064
Brugia malayi Kinase associated domain 1 family protein 0.0099 0.0141 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.032 0.1261 0.1261
Entamoeba histolytica hypothetical protein 0.0122 0.0255 0.1117
Loa Loa (eye worm) cyclin C 0.1034 0.4887 0.488
Loa Loa (eye worm) gastrulation defective protein 1 0.066 0.2986 0.2976
Schistosoma mansoni serine/threonine protein kinase 0.02 0.0653 0.0653
Echinococcus multilocularis mitogen activated protein kinase 14 0.0158 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.0099 0.0141 0.0127
Echinococcus granulosus cyclin 0.0513 0.2243 0.2243
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0095 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.011 0.0197 0.0182
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0249 0.0899 0.0885
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0094 0.0113 0.0113
Onchocerca volvulus 0.0135 0.0324 0.1653
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0135 0.0324 0.0275
Plasmodium falciparum NIMA related kinase 1 0.0135 0.0324 0.0276
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Onchocerca volvulus Neurogenic locus notch homolog 0.0206 0.0683 0.3548
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0223 0.0768 0.0768
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Plasmodium vivax thioredoxin reductase, putative 0.204 1 1
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0152 0.0411 0.0363
Echinococcus multilocularis Immunoglobulin 0.0112 0.0207 0.0207
Echinococcus granulosus glutamate synthase 0.0188 0.0589 0.0589
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Brugia malayi Immunoglobulin I-set domain containing protein 0.0386 0.1599 0.158
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0095 0.0121 0.0121
Trichomonas vaginalis mercuric reductase, putative 0.0707 0.3228 1
Echinococcus multilocularis fat cadherin tumor suppressor 0.0206 0.0683 0.0683
Giardia lamblia Kinase, AGC PKA 0.0155 0.0425 0.1151
Echinococcus multilocularis protein jagged 1 0.0206 0.0683 0.0683
Schistosoma mansoni protein kinase 0.0086 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0207 0.069 0.0676
Schistosoma mansoni kinase 0.0284 0.108 0.108
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.011 0.0197 0.0182
Echinococcus multilocularis cyclin 0.0513 0.2243 0.2243
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Schistosoma mansoni basigin related 0.0112 0.0207 0.0207
Schistosoma mansoni tyrosine kinase 0.0137 0.0331 0.0331
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0145 0.037 0.037
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Schistosoma mansoni protein kinase 0.0426 0.18 0.18
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0223 0.0768 0.0768
Schistosoma mansoni g1/s-specific cyclin C 0.1034 0.4887 0.4887
Loa Loa (eye worm) disorganized muscle protein 1 0.0095 0.012 0.0105
Echinococcus multilocularis dual specificity protein kinase clk2 0.0152 0.0411 0.0411
Onchocerca volvulus 0.01 0.0142 0.0691
Echinococcus granulosus casein kinase I alpha 0.0109 0.0188 0.0188
Brugia malayi Immunoglobulin I-set domain containing protein 0.0335 0.134 0.132
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0209 0.0493
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.0053 0.0038
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0184 0.057 0.0548
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0064 0.0052
Trypanosoma cruzi aurora B kinase, putative 0.0145 0.037 0.0359
Trichomonas vaginalis AGC family protein kinase 0.0135 0.0324 0.0854
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0158 0.0438 0.0427
Trichomonas vaginalis CAMK family protein kinase 0.0214 0.0725 0.2116
Brugia malayi EGF-like domain containing protein 0.0206 0.0683 0.0662
Echinococcus granulosus Immunoglobulin 0.0112 0.0207 0.0207
Schistosoma mansoni serine/threonine-protein kinase 0.0164 0.047 0.047
Brugia malayi SH2 domain containing protein 0.01 0.0142 0.012
Giardia lamblia Kinase, CMGC DYRK 0.0138 0.0338 0.0875
Brugia malayi Furin-like cysteine rich region family protein 0.0598 0.2675 0.2658
Onchocerca volvulus 0.01 0.0142 0.0691
Toxoplasma gondii NADPH-glutathione reductase 0.0707 0.3228 0.3194
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0197 0.0175
Loa Loa (eye worm) AUR protein kinase 0.0145 0.037 0.0356
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0095 0.012 0.012
Echinococcus granulosus N chimaerin 0.0094 0.0113 0.0113
Brugia malayi Protein kinase domain containing protein 0.0547 0.2413 0.2396
Loa Loa (eye worm) glutathione reductase 0.204 1 1
Schistosoma mansoni tyrosine kinase 0.0348 0.1406 0.1406

Activities

Activity type Activity value Assay description Source Reference
Deuterium retention (ADMET) = 58 % Compound incubated with microsomal preparations from phenobarbital treated male rats with the substrate rac 8-D and the amount of deuterium retained was reported after normal workup ChEMBL. 4020838
Deuterium retention (ADMET) = 58 % Amount of deuterium retained was reported after reincubation followed by normal workup in phenobarbital treated male rats with rac 8-D ChEMBL. 4020838
Deuterium retention (ADMET) = 76 % Amount of deuterium retained was reported after normal workup in beta-naphthoflavone-treated male rats with the substrate rac 7-D ChEMBL. 4020838
Deuterium retention (ADMET) = 76 % Compound incubated with microsomal preparations from beta-naphthoflavone-treated male rats with the substrate rac 7-D and the amount of deuterium retained was reported after reincubation followed by normal workup ChEMBL. 4020838
Deuterium retention (ADMET) = 82 % Amount of deuterium retained was reported after normal workup in rats ChEMBL. 4020838
Deuterium retention (ADMET) = 83 % Amount of deuterium retained was reported after reincubation followed by normal workup in phenobarbital treated male rats ChEMBL. 4020838
Potency (functional) 37.6858 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.