Detailed information for compound 311849

Basic information

Technical information
  • TDR Targets ID: 311849
  • Name: 2,8-dihydroxy-3-(3-oxo-1-phenylbutyl)chromen- 4-one
  • MW: 324.327 | Formula: C19H16O5
  • H donors: 2 H acceptors: 4 LogP: 2.42 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)CC(c1c(O)oc2c(c1=O)cccc2O)c1ccccc1
  • InChi: 1S/C19H16O5/c1-11(20)10-14(12-6-3-2-4-7-12)16-17(22)13-8-5-9-15(21)18(13)24-19(16)23/h2-9,14,21,23H,10H2,1H3
  • InChiKey: RCTGERXIFCOAHF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2,8-dihydroxy-3-(3-oxo-1-phenyl-butyl)chromen-4-one
  • 2,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-4-one
  • 2,8-dihydroxy-3-(3-keto-1-phenyl-butyl)chromone
  • 8-hydroxywarfarin
  • 2,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-4-chromenone
  • 17834-04-7
  • NCGC00165931-01
  • 2H-1-Benzopyran-2-one, 4,8-dihydroxy-3-(3-oxo-1-phenylbutyl)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Protein kinase domain containing protein 0.0114 0.0215 0.0192
Schistosoma mansoni basigin related 0.0112 0.0207 0.0207
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0188 0.0589 0.2584
Echinococcus multilocularis serine threonine protein kinase 0.0206 0.0684 0.0684
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.011 0.0197 0.0182
Brugia malayi Protein kinase domain containing protein 0.0198 0.0644 0.0623
Echinococcus granulosus aurora kinase A 0.0145 0.037 0.037
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0109 0.0188 0.0173
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0707 0.3228 0.3194
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase Blk 0.0186 0.0578 0.0578
Schistosoma mansoni ephrin receptor 0.0109 0.0191 0.0191
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0519 0.2274 0.2257
Brugia malayi Protein kinase domain containing protein 0.0166 0.0481 0.046
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Entamoeba histolytica protein kinase domain containing protein 0.0122 0.0255 0.1117
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Entamoeba histolytica protein kinase, putative 0.0296 0.1139 0.4994
Entamoeba histolytica hypothetical protein 0.0122 0.0255 0.1117
Mycobacterium ulcerans ferredoxin reductase 0.0188 0.0589 0.1455
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0361 0.1467 0.1455
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.322
Onchocerca volvulus 0.0206 0.0683 0.3548
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0233 0.082 0.082
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.0053 0.0038
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Echinococcus multilocularis neuroglian 0.0466 0.2005 0.2005
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0128 0.0287 0.0287
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0209 0.0161
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Onchocerca volvulus 0.0109 0.019 0.0945
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0707 0.3228 0.2803
Brugia malayi Protein kinase domain containing protein 0.0296 0.1139 0.1119
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0188 0.0589 0.0575
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0064 0.0035
Echinococcus multilocularis neurogenic locus protein delta 0.0206 0.0683 0.0683
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0084 0.0064 0.0015
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0188 0.0589 0.0543
Giardia lamblia Kinase, CAMK CAMKL 0.009 0.0092 0.0099
Onchocerca volvulus 0.0095 0.012 0.0571
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0115 0.0219 0.0219
Schistosoma mansoni serine/threonine protein kinase 0.013 0.0296 0.0296
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0128 0.0287 0.0272
Brugia malayi Protein kinase domain containing protein 0.0922 0.432 0.4307
Brugia malayi EGF-like domain containing protein 0.0206 0.0683 0.0662
Echinococcus granulosus insulin growth factor binding 0.0095 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Echinococcus multilocularis titin 0.0095 0.012 0.012
Trypanosoma cruzi casein kinase, putative 0.0109 0.0188 0.0176
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0188 0.0589 0.0579
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0128 0.0287 0.0276
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0188 0.0589 0.0589
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0223 0.0768 0.0768
Echinococcus granulosus cyclin dependent kinase 19 0.0694 0.3162 0.3162
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Echinococcus multilocularis insulin growth factor binding 0.0095 0.012 0.012
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0223 0.0768 0.0768
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0155 0.0425 0.0425
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0112 0.0207 0.0207
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0085 0.0068 0.03
Echinococcus granulosus casein kinase I alpha 0.0109 0.0188 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0316 0.0316
Brugia malayi Protein kinase domain containing protein 0.0211 0.0706 0.0685
Brugia malayi MAP kinase sur-1 0.0084 0.0064 0.0041
Entamoeba histolytica protein kinase domain containing protein 0.0128 0.0287 0.1257
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0247 0.0892 0.0892
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0707 0.3228 0.3194
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0084 0.0064 0.0015
Loa Loa (eye worm) hypothetical protein 0.0207 0.069 0.0676
Echinococcus multilocularis serine:threonine protein kinase N2 0.0166 0.0481 0.0481
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0707 0.3228 0.2803
Plasmodium falciparum calcium-dependent protein kinase 5 0.0101 0.0149 0.01
Echinococcus multilocularis tyrosine protein kinase Abl 0.0137 0.0331 0.0331
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0188 0.0589 0.0568
Echinococcus multilocularis roundabout 2 0.0223 0.0768 0.0768
Echinococcus granulosus titin 0.0095 0.012 0.012
Echinococcus multilocularis mitogen activated protein kinase 0.0084 0.0064 0.0064
Echinococcus granulosus notch 0.0206 0.0683 0.0683
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0149 0.0149
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0112 0.0207 0.0207
Brugia malayi serine/threonine protein kinase 6 0.0145 0.037 0.0348
Loa Loa (eye worm) TK/EPH protein kinase 0.0126 0.0278 0.0263
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0112 0.0207 0.0207
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0166 0.0481 0.0481
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0145 0.0373 0.0359
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0109 0.0188 0.0176
Entamoeba histolytica protein kinase domain containing protein 0.01 0.0145 0.0636
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.069 0.0669
Echinococcus granulosus tyrosine protein kinase Fyn 0.0223 0.0768 0.0768
Echinococcus granulosus CDC7 cell division cycle 7 0.009 0.0094 0.0094
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0114 0.0215 0.02
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.01 0.0145 0.0095
Schistosoma mansoni g1/s-specific cyclin C 0.1034 0.4887 0.4887
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0188 0.0425
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Schistosoma mansoni cell adhesion molecule 0.0223 0.0768 0.0768
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Brugia malayi protein-tyrosine kinase 0.0186 0.0578 0.0557
Plasmodium vivax glycogen synthase kinase 3, putative 0.0128 0.0287 0.0238
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0084 0.0061 0.0046
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0112 0.0207 0.0207
Echinococcus multilocularis insulin receptor 0.044 0.1869 0.1869
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0186 0.0583 0.0569
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0128 0.0287 0.0239
Schistosoma mansoni netrin receptor unc5 0.0112 0.0207 0.0207
Schistosoma mansoni hypothetical protein 0.0188 0.0589 0.0589
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0149 0.0149
Echinococcus multilocularis neurogenic locus notch protein 4 0.0206 0.0683 0.0683
Echinococcus multilocularis fibroblast growth factor receptor 4 0.024 0.0856 0.0856
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0892 0.0892
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0155 0.0425 0.0377
Echinococcus multilocularis roundabout 2 0.0594 0.2653 0.2653
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0145 0.037 0.1
Echinococcus granulosus casein kinase I delta 0.0109 0.0188 0.0188
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0109 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0234 0.0825 0.0811
Echinococcus multilocularis roundabout 2 0.0223 0.0768 0.0768
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0081 0.0049 0.0038
Schistosoma mansoni tyrosine kinase 0.0255 0.0932 0.0932
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0209 0.0187
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Onchocerca volvulus Peroxidasin homolog 0.0095 0.0121 0.0579
Onchocerca volvulus 0.0095 0.012 0.0571
Loa Loa (eye worm) hypothetical protein 0.0386 0.1599 0.1586
Echinococcus granulosus nervana 2 0.0121 0.0249 0.0249
Entamoeba histolytica PH domain containing protein kinase, putative 0.0164 0.047 0.206
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0086 0.0075 0.0075
Schistosoma mansoni protein kinase 0.0081 0.0049 0.0049
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0188 0.0188
Brugia malayi Furin-like cysteine rich region family protein 0.0598 0.2675 0.2658
Giardia lamblia Kinase, STE STE20 0.0085 0.0068 0.0024
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0082 0.005 0.0001
Brugia malayi Kinase associated domain 1 family protein 0.0099 0.0141 0.0119
Onchocerca volvulus 0.0381 0.157 0.8229
Brugia malayi Immunoglobulin I-set domain containing protein 0.0835 0.3877 0.3863
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Echinococcus multilocularis C type lectin domian containing protein 0.0381 0.157 0.157
Entamoeba histolytica protein kinase, putative 0.0145 0.037 0.1623
Brugia malayi Protein kinase domain containing protein 0.0588 0.2624 0.2607
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0078 0.0033 0.0033
Loa Loa (eye worm) protein kinase domain-containing protein 0.0211 0.0706 0.0692
Brugia malayi hypothetical protein 0.0219 0.0751 0.0729
Echinococcus granulosus neuroglian 0.0223 0.0768 0.0768
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0219 0.0751 0.0751
Trichomonas vaginalis STE family protein kinase 0.0086 0.0075 0.0071
Echinococcus multilocularis calcium activated potassium channel 0.0134 0.0317 0.0317
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0207 0.0184
Onchocerca volvulus 0.0074 0.0011 0.0001
Brugia malayi Egg laying defective protein 4 0.0134 0.0316 0.0294
Echinococcus granulosus tyrosine protein kinase otk 0.0207 0.069 0.069
Brugia malayi Doublecortin family protein 0.015 0.0397 0.0375
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.322
Schistosoma mansoni hypothetical protein 0.0095 0.012 0.012
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0152 0.0411 0.04
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0266 0.0989 0.0975
Schistosoma mansoni hypothetical protein 0.0112 0.0207 0.0207
Schistosoma mansoni protein kinase 0.0109 0.0188 0.0188
Brugia malayi Protein kinase domain 0.0086 0.0075 0.0052
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0206 0.0683 0.0662
Loa Loa (eye worm) hypothetical protein 0.0139 0.0344 0.033
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0707 0.3228 0.3194
Schistosoma mansoni growth factor receptor-bound protein 0.0092 0.0104 0.0104
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0188 0.0589 0.0543
Entamoeba histolytica hypothetical protein 0.0371 0.1521 0.6668
Brugia malayi Protein kinase c protein 2 0.0115 0.0222 0.02
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0995 0.4691 0.4691
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.009 0.0092 0.0043
Echinococcus granulosus dual specificity 0.0122 0.0255 0.0255
Schistosoma mansoni tyrosine kinase 0.0348 0.1406 0.1406
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.3194
Loa Loa (eye worm) hypothetical protein 0.0087 0.0079 0.0064
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0164 0.047 0.0459
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0411 0.0411
Echinococcus granulosus protein kinase shaggy 0.0128 0.0287 0.0287
Trichomonas vaginalis apoptosis inducing factor, putative 0.0188 0.0589 0.169
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0462 0.0462
Schistosoma mansoni tyrosine kinase 0.0541 0.2383 0.2383
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0188 0.0589 0.1455
Leishmania major hypothetical protein, conserved 0.0188 0.0589 0.0543
Loa Loa (eye worm) AGC/PKN protein kinase 0.0293 0.1124 0.1111
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Entamoeba histolytica protein kinase, putative 0.0084 0.0061 0.0267
Loa Loa (eye worm) hypothetical protein 0.009 0.0094 0.0079
Entamoeba histolytica protein kinase, putative 0.0166 0.0481 0.2111
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0188 0.0589 0.1455
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0109 0.019 0.019
Echinococcus multilocularis tyrosine protein kinase otk 0.0207 0.069 0.069
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.1397 0.1397
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0152 0.0411 0.0396
Schistosoma mansoni basigin related 0.0112 0.0207 0.0207
Mycobacterium ulcerans hypothetical protein 0.0188 0.0589 0.1455
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0707 0.3228 0.3193
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Leishmania major protein kinase, putative 0.0152 0.0411 0.0363
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0188 0.0589 0.1455
Loa Loa (eye worm) hypothetical protein 0.0423 0.1787 0.1774
Echinococcus multilocularis protein tyrosine kinase 0.0541 0.2383 0.2383
Echinococcus granulosus serine threonine protein kinase nrc 0.0155 0.0425 0.0425
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.02 0.0653 0.0639
Plasmodium falciparum serine/threonine protein kinase KIN 0.009 0.0092 0.0043
Loa Loa (eye worm) hypothetical protein 0.014 0.0348 0.0334
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0209 0.0161
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0163 0.0462 0.0448
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0137 0.0331 0.0331
Brugia malayi Immunoglobulin I-set domain containing protein 0.0145 0.0373 0.0351
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0128 0.0284 0.0284
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0191 0.0605 0.0591
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0101 0.0149 0.01
Schistosoma mansoni titin 0.0095 0.012 0.012
Schistosoma mansoni growth factor receptor-bound protein 0.009 0.0094 0.0094
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0707 0.3228 0.3228
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Trichomonas vaginalis mercuric reductase, putative 0.0707 0.3228 1
Plasmodium vivax protein kinase Crk2 0.0118 0.0238 0.0188
Schistosoma mansoni titin 0.0207 0.069 0.069
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0145 0.037 0.1623
Loa Loa (eye worm) hypothetical protein 0.0207 0.069 0.0676
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0122 0.0255 0.0207
Plasmodium vivax ferrodoxin reductase, putative 0.0188 0.0589 0.0542
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Brugia malayi SRC-1 0.0223 0.0768 0.0746
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0209 0.0194
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0707 0.3228 1
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Echinococcus multilocularis 0.017 0.0497 0.0497
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0188 0.0589 0.1455
Entamoeba histolytica protein kinase, putative 0.0102 0.0155 0.068
Onchocerca volvulus 0.009 0.0094 0.0436
Schistosoma mansoni kinase 0.0284 0.108 0.108
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0207 0.069 0.0676
Echinococcus multilocularis cyclin 0.0513 0.2243 0.2243
Entamoeba histolytica protein kinase domain containing protein 0.02 0.0653 0.2865
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.0238 0.0227
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0138 0.0338 0.0327
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0395 0.1643 0.1643
Echinococcus multilocularis CDC7 cell division cycle 7 0.009 0.0094 0.0094
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0188 0.0589 0.0589
Echinococcus granulosus titin 0.0095 0.012 0.012
Echinococcus multilocularis tyrosine protein kinase HCK 0.0133 0.0309 0.0309
Trypanosoma cruzi polo-like protein kinase, putative 0.0266 0.0989 0.0979
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0317 0.0317
Plasmodium falciparum glycogen synthase kinase 3 0.0128 0.0287 0.0239
Echinococcus granulosus tyrosine protein kinase ABL1 0.01 0.0142 0.0142
Giardia lamblia Kinase, CAMK CAMKL 0.009 0.0092 0.0099
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0397 0.1654 0.1654
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0215 0.0215
Leishmania major protein kinase, putative 0.0101 0.0149 0.01
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0485 0.21 0.21
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0411 0.0411
Entamoeba histolytica casein kinase, putative 0.0109 0.0188 0.0822
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0145 0.037 0.1623
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.0238 0.0227
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0249 0.0899 0.0899
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Schistosoma mansoni titin 0.0095 0.012 0.012
Echinococcus multilocularis twitchin 0.013 0.0296 0.0296
Plasmodium falciparum calcium-dependent protein kinase 4 0.0101 0.0149 0.01
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Loa Loa (eye worm) hypothetical protein 0.018 0.0552 0.0538
Schistosoma mansoni hemicentin 0.011 0.0197 0.0197
Echinococcus multilocularis Immunoglobulin subtype 0.0112 0.0207 0.0207
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0155 0.0425 0.0425
Brugia malayi EGF-like domain containing protein 0.0206 0.0683 0.0662
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0188 0.0589 0.0589
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0092 0.0092
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0214 0.0725 0.0711
Trypanosoma cruzi hypothetical protein, conserved 0.0188 0.0589 0.0579
Echinococcus multilocularis epidermal growth factor receptor 0.0598 0.2675 0.2675
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.02 0.0653 0.0653
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0138 0.0338 0.029
Echinococcus granulosus cGMP dependent protein kinase 1 0.0134 0.0316 0.0316
Echinococcus granulosus Immunoglobulin 0.0112 0.0207 0.0207
Brugia malayi Immunoglobulin I-set domain containing protein 0.0386 0.1599 0.158
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.322
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0095 0.012 0.0105
Echinococcus granulosus tyrosine protein kinase Fyn 0.0223 0.0768 0.0768
Onchocerca volvulus 0.018 0.0552 0.2854
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0198 0.0644 0.0644
Echinococcus multilocularis netrin receptor unc 5 0.0141 0.035 0.035
Schistosoma mansoni nephrin 0.0482 0.2082 0.2082
Loa Loa (eye worm) TK protein kinase 0.0133 0.0309 0.0295
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0223 0.0768 0.0768
Brugia malayi Protein kinase domain containing protein 0.0281 0.1062 0.1042
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0112 0.0207 0.0207
Schistosoma mansoni peroxidasin 0.0113 0.0208 0.0208
Echinococcus granulosus serine:threonine protein kinase 3 0.0253 0.0922 0.0922
Onchocerca volvulus 0.0095 0.012 0.0571
Loa Loa (eye worm) hypothetical protein 0.011 0.0197 0.0182
Echinococcus multilocularis epidermal growth factor receptor 0.0395 0.1643 0.1643
Brugia malayi hypothetical protein 0.0386 0.1599 0.158
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0188 0.0589 0.0543
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Brugia malayi Fes/CIP4 homology domain containing protein 0.0111 0.0202 0.0179
Trypanosoma cruzi trypanothione reductase, putative 0.0707 0.3228 0.322
Trichomonas vaginalis AGC family protein kinase 0.0145 0.037 0.1
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0101 0.0149 0.0134
Trichomonas vaginalis AGC family protein kinase 0.0186 0.0583 0.167
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0118 0.0238 0.0189
Plasmodium falciparum cGMP-dependent protein kinase 0.0134 0.0316 0.0268
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.01 0.0145 0.013
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0112 0.0207 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.0706 0.0706
Plasmodium falciparum casein kinase 2, alpha subunit 0.01 0.0145 0.0096
Loa Loa (eye worm) hypothetical protein 0.0135 0.0324 0.031
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0213 0.072 0.072
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0207 0.069 0.0676
Plasmodium falciparum apical sushi protein 0.0381 0.157 0.1528
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0145 0.037 0.037
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0095 0.012 0.012
Schistosoma mansoni protein kinase 0.0191 0.0605 0.0605
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Echinococcus granulosus serine/threonine protein kinase 0.0164 0.047 0.047
Brugia malayi Fibronectin type III domain containing protein 0.0386 0.1599 0.158
Echinococcus granulosus protein jagged 1 0.0206 0.0683 0.0683
Plasmodium vivax glutathione reductase, putative 0.204 1 1
Brugia malayi Homeodomain interacting protein kinase protein 1 0.02 0.0653 0.0632
Brugia malayi serine/threonine kinase 12 0.0145 0.037 0.0348
Echinococcus granulosus NCK adaptor protein 0.009 0.0094 0.0094
Loa Loa (eye worm) cyclin domain-containing protein 0.0513 0.2243 0.2231
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0223 0.0768 0.0768
Loa Loa (eye worm) AGC/NDR protein kinase 0.0166 0.0481 0.0467
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0095 0.012 0.0105
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0232 0.0814 0.0814
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0215 0.051
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.322
Toxoplasma gondii NADPH-glutathione reductase 0.0707 0.3228 0.3194
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.009 0.0092 0.0042
Brugia malayi Prion-like- 0.0207 0.069 0.0669
Loa Loa (eye worm) TK/FAK protein kinase 0.0547 0.2413 0.2402
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0184 0.057 0.0556
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0257 0.0944 0.093
Trichomonas vaginalis glutathione reductase, putative 0.0707 0.3228 1
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0081 0.0081
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0095 0.012 0.0097
Echinococcus granulosus neuroglian 0.0466 0.2005 0.2005
Mycobacterium tuberculosis Probable oxidoreductase 0.0707 0.3228 0.2803
Plasmodium falciparum NIMA related kinase 1 0.0135 0.0324 0.0276
Echinococcus granulosus protein jagged 1 0.0206 0.0683 0.0683
Echinococcus multilocularis cyclin dependent kinase 0.0118 0.0238 0.0238
Toxoplasma gondii aurora kinase 0.0145 0.037 0.0322
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0086 0.0075 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.0126 0.0275 0.0701
Schistosoma mansoni myosin-binding protein-related 0.011 0.0197 0.0197
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Schistosoma mansoni glutamate synthase 0.0188 0.0589 0.0589
Echinococcus granulosus cyclin dependent kinase 0.0118 0.0238 0.0238
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0707 0.3228 0.322
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0387 0.1603 0.1591
Brugia malayi map kinase activated protein kinase protein 2 0.0387 0.1603 0.1584
Brugia malayi Protein kinase domain containing protein 0.0347 0.1397 0.1377
Loa Loa (eye worm) hypothetical protein 0.008 0.004 0.0025
Echinococcus multilocularis mitogen activated protein kinase 14 0.0158 0.0438 0.0438
Echinococcus granulosus defective proboscis extension response 0.0371 0.1521 0.1521
Loa Loa (eye worm) TK/ALK protein kinase 0.0278 0.1046 0.1033
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0707 0.3228 0.322
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0266 0.0989 0.0944
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0138 0.0338 0.029
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0338 0.0898
Brugia malayi Stress-activated protein kinase jnk-1 0.026 0.0959 0.0938
Schistosoma mansoni tyrosine kinase 0.0395 0.1643 0.1643
Entamoeba histolytica disulphide oxidoreductase, putative 0.0188 0.0589 0.2584
Brugia malayi Muscle positioning protein 4 0.0206 0.0683 0.0662
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Echinococcus granulosus nervana 2 0.0121 0.0249 0.0249
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0751 0.0751
Brugia malayi glutamate synthase 0.0188 0.0589 0.0568
Brugia malayi casein kinase 1, delta 0.0109 0.0188 0.0165
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.0238 0.0238
Schistosoma mansoni nephrin 0.0223 0.0768 0.0768
Loa Loa (eye worm) Notch2 0.0206 0.0683 0.0669
Echinococcus granulosus protein jagged 2 0.0206 0.0683 0.0683
Trichomonas vaginalis CAMK family protein kinase 0.0214 0.0725 0.2116
Giardia lamblia Thioredoxin reductase 0.0188 0.0589 0.1669
Schistosoma mansoni serine/threonine protein kinase 0.032 0.1261 0.1261
Schistosoma mansoni protein kinase 0.0086 0.0075 0.0075
Brugia malayi Delta serrate ligand family protein 0.0206 0.0683 0.0662
Echinococcus granulosus fibropellin Ia 0.0206 0.0683 0.0683
Schistosoma mansoni cell adhesion molecule 0.011 0.0197 0.0197
Echinococcus multilocularis raf serine:threonine protein kinase 0.0088 0.0081 0.0081
Trypanosoma cruzi trypanothione reductase, putative 0.204 1 1
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0084 0.0061 0.0012
Toxoplasma gondii rhoptry neck protein RON9 0.0381 0.157 0.1528
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0095 0.012 0.012
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0266 0.0989 0.0989
Giardia lamblia Kinase, NEK 0.0135 0.0324 0.0831
Echinococcus granulosus casein kinase i 0.0109 0.0188 0.0188
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0158 0.0438 0.039
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0145 0.037 0.037
Entamoeba histolytica protein kinase , putative 0.0145 0.037 0.1623
Entamoeba histolytica PH domain containing protein kinase, putative 0.0122 0.0254 0.1112
Onchocerca volvulus Peroxidasin homolog 0.0095 0.012 0.0571
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0184 0.057 0.057
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0287 0.0737
Loa Loa (eye worm) sex muscle abnormal protein 5 0.009 0.0094 0.0079
Entamoeba histolytica protein kinase, putative 0.0074 0.0012 0.0053
Plasmodium falciparum casein kinase 1 0.0109 0.0188 0.0139
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0112 0.0207 0.0207
Echinococcus granulosus epidermal growth factor receptor 0.0395 0.1643 0.1643
Echinococcus multilocularis casein kinase I delta 0.0109 0.0188 0.0188
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Brugia malayi Peroxidasin 0.0208 0.0691 0.067
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0095 0.012 0.0105
Schistosoma mansoni hypothetical protein 0.011 0.0197 0.0197
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0118 0.0238 0.0238
Brugia malayi SH2 domain containing protein 0.01 0.0142 0.012
Echinococcus granulosus casein kinase ii subunit alpha 0.01 0.0145 0.0145
Echinococcus multilocularis neurogenic locus protein delta 0.0206 0.0683 0.0683
Onchocerca volvulus 0.0145 0.0373 0.1911
Plasmodium vivax calcium-dependent protein kinase, putative 0.0101 0.0149 0.0099
Trypanosoma cruzi casein kinase, putative 0.0109 0.0188 0.0176
Brugia malayi Protein kinase domain containing protein 0.0163 0.0462 0.0441
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0513 0.2243 0.2243
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0215 0.0215
Loa Loa (eye worm) glutathione reductase 0.204 1 1
Echinococcus granulosus neurogenic locus notch protein 4 0.0206 0.0683 0.0683
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Trypanosoma brucei polo-like protein kinase 0.0266 0.0989 0.0944
Echinococcus multilocularis ephrin type A receptor 4 A 0.0109 0.0191 0.0191
Brugia malayi Cyclin, N-terminal domain containing protein 0.0513 0.2243 0.2225
Entamoeba histolytica protein kinase, putative 0.0082 0.0053 0.0231
Brugia malayi Immunoglobulin I-set domain containing protein 0.0223 0.0768 0.0747
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0253 0.0922 0.0909
Onchocerca volvulus 0.0109 0.0188 0.093
Echinococcus granulosus lachesin 0.0207 0.069 0.069
Echinococcus granulosus Immunoglobulin 0.0112 0.0207 0.0207
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0084 0.0064 0.0052
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0707 0.3228 0.3194
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0249 0.0899 0.0885
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0086 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0386 0.1599 0.1586
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Echinococcus granulosus glutamate synthase 0.0188 0.0589 0.0589
Brugia malayi Immunoglobulin I-set domain containing protein 0.0123 0.0261 0.0239
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0128 0.0287 0.0272
Echinococcus multilocularis thioredoxin glutathione reductase 0.204 1 1
Toxoplasma gondii thioredoxin reductase 0.204 1 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0361 0.1467 0.1467
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0085 0.0068 0.03
Loa Loa (eye worm) thyroid receptor interactor 0.0111 0.0202 0.0187
Brugia malayi Prion-like- 0.0095 0.012 0.0097
Echinococcus multilocularis dual specificity 0.0138 0.0338 0.0338
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0209 0.016
Schistosoma mansoni hypothetical protein 0.0095 0.012 0.012
Brugia malayi hypothetical protein 0.01 0.0142 0.012
Entamoeba histolytica protein kinase domain containing protein 0.0128 0.0287 0.1257
Entamoeba histolytica casein kinase, putative 0.01 0.0145 0.0636
Brugia malayi cell division control protein 2 homolog 0.0118 0.0238 0.0215
Loa Loa (eye worm) hypothetical protein 0.0135 0.0324 0.031
Echinococcus granulosus casein kinase I alpha 0.0109 0.0188 0.0188
Echinococcus granulosus neural cadherin 0.0206 0.0683 0.0683
Echinococcus granulosus tyrosine protein kinase HCK 0.0133 0.0309 0.0309
Schistosoma mansoni vav2 0.0103 0.0157 0.0157
Schistosoma mansoni disulfide oxidoreductase 0.0188 0.0589 0.0589
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0128 0.0284 0.027
Trypanosoma cruzi casein kinase, putative 0.0109 0.0188 0.0176
Echinococcus multilocularis tyrosine protein kinase 0.0281 0.1062 0.1062
Toxoplasma gondii casein kinase I 0.0109 0.0188 0.0139
Onchocerca volvulus 0.0381 0.157 0.8229
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0208 0.0695 0.0681
Onchocerca volvulus 0.01 0.0142 0.0691
Brugia malayi Immunoglobulin I-set domain containing protein 0.0335 0.134 0.132
Onchocerca volvulus 0.0381 0.157 0.8229
Echinococcus multilocularis cyclin dependent kinase 5 0.0118 0.0238 0.0238
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0223 0.0768 0.0768
Schistosoma mansoni tyrosine kinase 0.0348 0.1406 0.1406
Echinococcus granulosus neurogenic locus notch protein 0.0206 0.0683 0.0683
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0112 0.0207 0.0207
Entamoeba histolytica casein kinase 1, putative 0.0109 0.0188 0.0822
Echinococcus granulosus epidermal growth factor receptor 0.0598 0.2675 0.2675
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0188 0.0589 0.0543
Leishmania major trypanothione reductase 0.204 1 1
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0113 0.0209 0.0161
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0061 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0126 0.0275 0.0701
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0158 0.0438 0.0427
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0373 0.0373
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0155 0.0425 0.0378
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0287 0.1095 0.1081
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0166 0.0481 0.0481
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0188 0.0589 0.1455
Loa Loa (eye worm) TK protein kinase 0.0281 0.1062 0.1049
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0188 0.0589 0.0543
Schistosoma mansoni septate junction protein 0.0112 0.0207 0.0207
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0223 0.0768 0.0768
Brugia malayi Sex muscle abnormal protein 5 0.009 0.0094 0.0072
Brugia malayi Calcium binding EGF domain containing protein 0.0206 0.0683 0.0662
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0112 0.0207 0.0207
Echinococcus multilocularis protein jagged 1 0.0206 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0135 0.0324 0.031
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0064 0.0035
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0084 0.0064 0.0015
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0213 0.072 0.072
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0223 0.0768 0.0768
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0188 0.0589 0.0589
Trypanosoma cruzi aurora B kinase, putative 0.0145 0.037 0.0359
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0092 0.0092
Echinococcus granulosus protein kinase C gamma type 0.0206 0.0684 0.0684
Echinococcus multilocularis neural cadherin 0.0206 0.0683 0.0683
Onchocerca volvulus 0.0305 0.1185 0.6195
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0101 0.0149 0.0099
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Mycobacterium ulcerans glutamate synthase subunit beta 0.0188 0.0589 0.1455
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0707 0.3228 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0707 0.3228 1
Loa Loa (eye worm) cyclin C 0.1034 0.4887 0.488
Echinococcus multilocularis titin 0.0095 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Trypanosoma cruzi NADH dehydrogenase, putative 0.0188 0.0589 0.0579
Echinococcus granulosus mitogen activated protein kinase 14 0.0158 0.0438 0.0438
Echinococcus granulosus leucine rich repeat containing protein 4 0.0095 0.012 0.012
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0117 0.0229 0.0207
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0086 0.0075 0.0075
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0084 0.0064 0.0015
Giardia lamblia Aurora kinase 0.0145 0.037 0.0977
Onchocerca volvulus 0.0285 0.1085 0.5669
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0707 0.3228 1
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0086 0.0075 0.0075
Plasmodium vivax serine/threonine protein kinase, putative 0.0084 0.0061 0.001
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0158 0.0438 0.0427
Loa Loa (eye worm) hypothetical protein 0.0587 0.2617 0.2606
Schistosoma mansoni slit 0.0095 0.0121 0.0121
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0188 0.0589 0.2584
Echinococcus multilocularis dual specificity 0.0122 0.0255 0.0255
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0188 0.0589 0.169
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Schistosoma mansoni septate junction protein 0.0206 0.0683 0.0683
Onchocerca volvulus Neurogenic locus notch homolog 0.0206 0.0683 0.3548
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0188 0.0589 0.0543
Schistosoma mansoni protein kinase 0.0261 0.0962 0.0962
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0095 0.0121 0.0121
Schistosoma mansoni septate junction protein 0.0112 0.0207 0.0207
Brugia malayi Tyrosine-protein kinase abl-1 0.0137 0.0331 0.0309
Brugia malayi Protein kinase domain containing protein 0.01 0.0142 0.012
Brugia malayi Protein kinase domain containing protein 0.0214 0.0725 0.0703
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0207 0.069 0.069
Trichomonas vaginalis AGC family protein kinase 0.0186 0.0583 0.167
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Leishmania major protein kinase A catalytic subunit 0.0113 0.0209 0.0161
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0892 0.0892
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0481 0.0481
Plasmodium falciparum calcium-dependent protein kinase 2 0.0101 0.0149 0.01
Echinococcus multilocularis hemicentin 1 0.0207 0.069 0.069
Plasmodium vivax unspecified product 0.01 0.0145 0.0095
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0188 0.0589 0.0589
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0084 0.0064 0.0052
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0325 0.1288 0.1275
Schistosoma mansoni serine/threonine protein kinase 0.02 0.0653 0.0653
Echinococcus multilocularis 0.0095 0.012 0.012
Loa Loa (eye worm) LAD-2 short isoform 0.0112 0.0207 0.0192
Brugia malayi Serine/threonine-protein kinase SULU 0.0219 0.0751 0.0729
Echinococcus multilocularis hypothetical protein 0.0099 0.0141 0.0141
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Echinococcus granulosus contactin 0.0223 0.0768 0.0768
Loa Loa (eye worm) notch protein 0.0206 0.0683 0.0669
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Echinococcus multilocularis N chimaerin 0.0094 0.0113 0.0113
Schistosoma mansoni protein kinase 0.0233 0.082 0.082
Loa Loa (eye worm) hypothetical protein 0.0118 0.0235 0.022
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0155 0.0425 0.0414
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0082 0.005 0.0001
Onchocerca volvulus 0.0095 0.012 0.0571
Schistosoma mansoni serine/threonine protein kinase 0.0208 0.0695 0.0695
Schistosoma mansoni hypothetical protein 0.0095 0.012 0.012
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0209 0.0198
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Entamoeba histolytica serine/threonine protein kinase, putative 0.0266 0.0989 0.4336
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0144 0.0366 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0219 0.0525
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Brugia malayi Protein kinase domain containing protein 0.009 0.0094 0.0071
Brugia malayi Cadherin domain containing protein 0.0206 0.0683 0.0662
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.035 0.0328
Schistosoma mansoni atypical protein kinase C 0.0294 0.113 0.113
Giardia lamblia Kinase, STE STE20 0.0086 0.0075 0.0046
Echinococcus multilocularis serine:threonine protein kinase N2 0.0293 0.1124 0.1124
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.069 0.0669
Schistosoma mansoni cell adhesion molecule 0.0095 0.012 0.012
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0223 0.0768 0.0768
Trichomonas vaginalis CMGC family protein kinase 0.0152 0.0411 0.1127
Echinococcus granulosus cyclin 0.0513 0.2243 0.2243
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0095 0.012 0.012
Echinococcus granulosus C type lectin domian containing protein 0.0381 0.157 0.157
Loa Loa (eye worm) hypothetical protein 0.0112 0.0207 0.0192
Schistosoma mansoni notch 0.0206 0.0683 0.0683
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.204 1 1
Brugia malayi pregnancy-associated plasma protein-A 0.0381 0.157 0.155
Loa Loa (eye worm) hypothetical protein 0.0371 0.1523 0.151
Echinococcus multilocularis dual specificity 0.0138 0.0338 0.0338
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.0814 0.0814
Brugia malayi Protein kinase domain containing protein 0.0278 0.1046 0.1026
Echinococcus multilocularis rac serine:threonine kinase 0.0164 0.047 0.047
Onchocerca volvulus 0.0095 0.012 0.0571
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0233 0.082 0.082
Giardia lamblia Kinase, PLK 0.0266 0.0989 0.2931
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0125 0.0274 0.0225
Giardia lamblia Kinase, CMGC MAPK 0.0084 0.0064 0.001
Loa Loa (eye worm) hypothetical protein 0.0188 0.0589 0.0575
Echinococcus granulosus c-Jun N-terminal kinases 0.026 0.0959 0.0959
Echinococcus multilocularis fibropellin Ia 0.0206 0.0683 0.0683
Plasmodium falciparum glutathione reductase 0.204 1 1
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0215 0.0215
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0138 0.0338 0.0316
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0092 0.0092
Echinococcus granulosus tyrosine protein kinase Srms 0.0498 0.2164 0.2164
Echinococcus multilocularis 0.0152 0.0408 0.0408
Brugia malayi Protein kinase domain containing protein 0.0084 0.0061 0.0038
Leishmania major casein kinase, putative 0.0109 0.0188 0.0139
Onchocerca volvulus 0.0206 0.0683 0.3548
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0206 0.0683 0.3548
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Schistosoma mansoni protein kinase 0.0426 0.18 0.18
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0188 0.0589 0.0543
Echinococcus granulosus mitogen activated protein kinase 11 0.0158 0.0438 0.0438
Trypanosoma cruzi casein kinase II, putative 0.01 0.0145 0.0134
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0128 0.0284 0.0284
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0101 0.0149 0.01
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0184 0.057 0.0548
Giardia lamblia Kinase, AGC PKA 0.0113 0.0209 0.0469
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0209 0.0194
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0188 0.0188
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0101 0.0149 0.01
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0141 0.0351 0.0351
Leishmania major casein kinase II, putative 0.01 0.0145 0.0096
Schistosoma mansoni tyrosine kinase 0.0077 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0209 0.0209
Plasmodium vivax casein kinase 1, putative 0.0109 0.0188 0.0138
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0095 0.0121 0.0121
Toxoplasma gondii AGC kinase 0.0113 0.0209 0.0161
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Echinococcus granulosus cGMP dependent protein kinase 1 0.0134 0.0316 0.0316
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0094 0.0129
Toxoplasma gondii histone kinase SNF1, putative 0.009 0.0092 0.0043
Loa Loa (eye worm) TK/INSR protein kinase 0.044 0.1869 0.1857
Toxoplasma gondii AGC kinase 0.0287 0.1095 0.1051
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0426 0.18 0.18
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0188 0.0589 0.169
Schistosoma mansoni serine/threonine kinase 0.0166 0.0481 0.0481
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0122 0.0255 0.0207
Schistosoma mansoni titin 0.0095 0.012 0.012
Trypanosoma brucei NADH dehydrogenase 0.0188 0.0589 0.0543
Schistosoma mansoni nephrin related 0.0095 0.012 0.012
Echinococcus multilocularis dual specificity 0.0138 0.0338 0.0338
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0209 0.0209
Echinococcus multilocularis neurogenic locus notch protein 0.0206 0.0683 0.0683
Loa Loa (eye worm) AGC/AKT protein kinase 0.0296 0.1139 0.1126
Schistosoma mansoni glutamate synthase 0.0188 0.0589 0.0589
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0188 0.0589 0.0543
Brugia malayi EGF-like domain containing protein 0.0234 0.0825 0.0804
Echinococcus granulosus dual specificity protein kinase clk2 0.0152 0.0411 0.0411
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0094 0.0094
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0209 0.0198
Brugia malayi Calcium binding EGF domain containing protein 0.0206 0.0683 0.0662
Echinococcus multilocularis protein kinase c iota type 0.0288 0.11 0.11
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0122 0.0255 0.024
Brugia malayi casein kinase I 0.0109 0.0188 0.0165
Trypanosoma brucei cdc2-related kinase 1 0.0118 0.0238 0.0189
Schistosoma mansoni hypothetical protein 0.0099 0.0141 0.0141
Echinococcus multilocularis nervana 2 0.0121 0.0249 0.0249
Echinococcus multilocularis rho associated protein kinase 0.032 0.1261 0.1261
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0085 0.0068 0.0019
Entamoeba histolytica protein kinase, putative 0.0101 0.0149 0.0652
Echinococcus granulosus N chimaerin 0.0094 0.0113 0.0113
Brugia malayi Cyclin C 0.1034 0.4887 0.4876
Schistosoma mansoni tyrosine kinase 0.0223 0.0768 0.0768
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0455 0.1947 0.1947
Schistosoma mansoni titin 0.0145 0.0373 0.0373
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0149 0.0149
Schistosoma mansoni tyrosine kinase 0.0223 0.0768 0.0768
Onchocerca volvulus 0.0206 0.0683 0.3548
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0162 0.0461 0.0446
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0086 0.0075 0.0075
Brugia malayi p70 ribosomal S6 kinase beta 0.0287 0.1095 0.1074
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0081 0.0049 0.0038
Loa Loa (eye worm) hypothetical protein 0.0114 0.0215 0.02
Brugia malayi serine/threonine-protein kinase 6 0.0145 0.037 0.0348
Brugia malayi Prion-like- 0.0095 0.012 0.0097
Echinococcus multilocularis neuroglian 0.0223 0.0768 0.0768
Loa Loa (eye worm) CDC7 protein kinase 0.009 0.0094 0.0079
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0144 0.0367 0.0367
Schistosoma mansoni sulfide quinone reductase 0.0188 0.0589 0.0589
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Echinococcus granulosus calcium activated potassium channel 0.0134 0.0317 0.0317
Brugia malayi Myb-like DNA-binding domain containing protein 0.0095 0.012 0.0097
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0094 0.0129
Schistosoma mansoni cell adhesion molecule 0.0112 0.0207 0.0207
Echinococcus granulosus tyrosine protein kinase Lyn 0.0257 0.0944 0.0944
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0188 0.0589 0.0579
Schistosoma mansoni roundabout 0.0207 0.069 0.069
Echinococcus granulosus titin 0.0145 0.0373 0.0373
Schistosoma mansoni serine/threonine-protein kinase 0.0164 0.047 0.047
Echinococcus granulosus casein kinase I alpha 0.0109 0.0188 0.0188
Echinococcus multilocularis death associated protein kinase 1 0.0831 0.3856 0.3856
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Echinococcus granulosus insulin receptor 0.044 0.1869 0.1869
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0094 0.0113 0.0113
Brugia malayi Variant SH3 domain containing protein 0.009 0.0094 0.0072
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0188 0.0589 0.0589
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0371 0.1521 0.1521
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Loa Loa (eye worm) hypothetical protein 0.0189 0.0596 0.0582
Echinococcus granulosus hypothetical protein 0.0118 0.0235 0.0235
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0223 0.0768 0.0768
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0134 0.0316 0.0316
Echinococcus granulosus cGMP dependent protein kinase 0.0134 0.0316 0.0316
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0152 0.0411 0.04
Trypanosoma cruzi casein kinase, putative 0.0109 0.0188 0.0176
Brugia malayi P38 map kinase family protein 2 0.0158 0.0438 0.0416
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Loa Loa (eye worm) hypothetical protein 0.0208 0.0691 0.0677
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0152 0.0411 0.04
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.024 0.0856 0.0856
Echinococcus granulosus titin 0.0145 0.0373 0.0373
Echinococcus granulosus roundabout 2 0.0223 0.0768 0.0768
Giardia lamblia Kinase, NEK 0.0135 0.0324 0.0831
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0426 0.18 0.18
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0158 0.0438 0.0423
Mycobacterium ulcerans monoxygenase 0.0188 0.0589 0.1455
Echinococcus multilocularis down syndrome cell adhesion 0.0095 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0219 0.0751 0.0737
Loa Loa (eye worm) hypothetical protein 0.0084 0.0062 0.0047
Schistosoma mansoni protein kinase 0.0086 0.0075 0.0075
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0188 0.0589 0.0579
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0122 0.0255 0.0244
Onchocerca volvulus 0.0189 0.0596 0.3088
Brugia malayi Cam kinase protein 1 0.0101 0.0149 0.0126
Entamoeba histolytica PH domain containing protein kinase, putative 0.0164 0.047 0.206
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Loa Loa (eye worm) AUR protein kinase 0.0145 0.037 0.0356
Entamoeba histolytica protein kinase, putative 0.0122 0.0255 0.1117
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Loa Loa (eye worm) AGC/PKG protein kinase 0.0134 0.0316 0.0302
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0174 0.052 0.0506
Brugia malayi Immunoglobulin domain containing protein 0.0112 0.0207 0.0184
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0101 0.0149 0.0134
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0238 0.0583
Schistosoma mansoni protein kinase 0.0426 0.18 0.18
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.0238 0.0227
Echinococcus granulosus protein kinase c iota type 0.0288 0.11 0.11
Schistosoma mansoni titin 0.0095 0.012 0.012
Echinococcus multilocularis transfer RNA-Phe 0.011 0.0197 0.0197
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Giardia lamblia Kinase, CK1 Casein kinase 0.0109 0.0188 0.04
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0188 0.0589 0.0589
Schistosoma mansoni laminin gamma-3 chain 0.0206 0.0683 0.0683
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0134 0.0316 0.0268
Echinococcus multilocularis activin receptor type 0.0081 0.0049 0.0049
Brugia malayi EGF-like domain containing protein 0.0206 0.0683 0.0662
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0101 0.0149 0.0099
Schistosoma mansoni sulfide quinone reductase 0.0188 0.0589 0.0589
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0109 0.0188 0.0173
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0109 0.0188 0.0173
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0053 0.0053
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0347 0.1397 0.1377
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0144 0.0366 0.0366
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0113 0.0209 0.0161
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Giardia lamblia Kinase, AGC AKT 0.0117 0.0229 0.0532
Loa Loa (eye worm) hypothetical protein 0.0112 0.0207 0.0192
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0316 0.0316
Schistosoma mansoni nck2/grb4 0.009 0.0094 0.0094
Brugia malayi intracellular kinase 0.0128 0.0287 0.0265
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.011 0.0197 0.0182
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.026 0.0959 0.0946
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0197 0.0175
Echinococcus multilocularis nervana 2 0.0121 0.0249 0.0249
Brugia malayi serine/threonine-protein kinase plk-2 0.0266 0.0989 0.0968
Loa Loa (eye worm) TK protein kinase 0.0186 0.0578 0.0564
Echinococcus granulosus titin 0.0095 0.012 0.012
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0188 0.0425
Brugia malayi putative serine/threonine kinase SADA gamma 0.009 0.0092 0.0069
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0371 0.1521 0.1521
Echinococcus granulosus tyrosine protein kinase Src42A 0.0141 0.0351 0.0351
Echinococcus multilocularis casein kinase I gamma 0.0211 0.0706 0.0706
Echinococcus granulosus c src tyrosine kinase 0.0137 0.0331 0.0331
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0215 0.0215
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0347 0.1397 0.1384
Loa Loa (eye worm) hypothetical protein 0.0203 0.0668 0.0654
Echinococcus multilocularis cyclin dependent kinase 19 0.0694 0.3162 0.3162
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0266 0.0989 0.0989
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0209 0.0198
Echinococcus multilocularis hemicentin 1 0.0207 0.069 0.069
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0208 0.0186
Entamoeba histolytica protein kinase, putative 0.0145 0.037 0.1623
Echinococcus granulosus protein jagged 2 0.0206 0.0683 0.0683
Schistosoma mansoni c4b-binding protein beta chain 0.0381 0.157 0.157
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0188 0.0589 0.169
Leishmania major hypothetical protein, conserved 0.0188 0.0589 0.0543
Schistosoma mansoni hypothetical protein 0.0095 0.012 0.012
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.0814 0.0814
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0284 0.0262
Echinococcus granulosus fibroblast growth factor receptor 4 0.024 0.0856 0.0856
Giardia lamblia Kinase, CMGC CDK 0.0118 0.0238 0.0559
Plasmodium falciparum thioredoxin reductase 0.204 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0223 0.0768 0.0768
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Schistosoma mansoni protein kinase C mu 0.0215 0.0728 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0092 0.0092
Echinococcus multilocularis serine:threonine protein kinase 3 0.0253 0.0922 0.0922
Loa Loa (eye worm) hypothetical protein 0.0139 0.0344 0.033
Mycobacterium ulcerans dehydrogenase 0.0188 0.0589 0.1455
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0186 0.0578 0.0578
Echinococcus granulosus ephrin type A receptor 4 A 0.0109 0.0191 0.0191
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0218 0.0218
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0694 0.3162 0.3152
Schistosoma mansoni septate junction protein 0.0207 0.069 0.069
Loa Loa (eye worm) hypothetical protein 0.0112 0.0207 0.0192
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0396 0.1647 0.1647
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.009 0.0092 0.0043
Schistosoma mansoni tyrosine kinase 0.0137 0.0331 0.0331
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0188 0.0589 0.1669
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0101 0.0149 0.0099
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0152 0.0407 0.1115
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0588 0.2624 0.2613
Loa Loa (eye worm) hypothetical protein 0.011 0.0197 0.0182
Brugia malayi Heparan sulfate 0.0112 0.0207 0.0184
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0121 0.0249 0.0249
Entamoeba histolytica protein kinase, putative 0.0074 0.0012 0.0053
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0347 0.1397 0.1384
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.057 0.057
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0485 0.21 0.21
Entamoeba histolytica protein kinase domain containing protein 0.0081 0.0049 0.0216
Echinococcus granulosus mitogen activated protein kinase 3 0.0084 0.0064 0.0064
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0513 0.2243 0.2243
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Entamoeba histolytica protein kinase, putative 0.0084 0.0061 0.0267
Schistosoma mansoni tyrosine kinase 0.0598 0.2675 0.2675
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0144 0.0367 0.0367
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0094 0.0113 0.0098
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Echinococcus granulosus activin receptor type 0.0081 0.0049 0.0049
Echinococcus multilocularis expressed conserved protein 0.0134 0.0316 0.0316
Echinococcus granulosus Immunoglobulin subtype 0.0112 0.0207 0.0207
Trypanosoma cruzi NADH dehydrogenase, putative 0.0188 0.0589 0.0579
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0094 0.0113 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.0468 0.2014 0.2014
Brugia malayi Temporarily assigned gene name protein 59 0.0109 0.019 0.0168
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Schistosoma mansoni notch 0.0206 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Echinococcus multilocularis mitogen activated protein kinase 14 0.0158 0.0438 0.0438
Onchocerca volvulus 0.0139 0.0344 0.1759
Toxoplasma gondii CMGC kinase, CK2 family 0.01 0.0145 0.0096
Brugia malayi Hr1 repeat family protein 0.0293 0.1124 0.1104
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0112 0.0207 0.0207
Loa Loa (eye worm) TK protein kinase 0.0343 0.1378 0.1365
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0188 0.0589 0.2584
Brugia malayi Protein kinase domain containing protein 0.0186 0.0583 0.0561
Schistosoma mansoni notch 0.0206 0.0683 0.0683
Schistosoma mansoni basigin related 0.0112 0.0207 0.0207
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Onchocerca volvulus 0.01 0.0142 0.0691
Entamoeba histolytica p21-activated kinase 0.0095 0.012 0.0524
Echinococcus granulosus netrin receptor unc 5 0.0141 0.035 0.035
Loa Loa (eye worm) disorganized muscle protein 1 0.0095 0.012 0.0105
Loa Loa (eye worm) CAMK protein kinase 0.0145 0.0373 0.0359
Schistosoma mansoni cell polarity protein 0.0206 0.0683 0.0683
Onchocerca volvulus Slit protein homolog 0.0234 0.0825 0.4298
Echinococcus granulosus roundabout 2 0.0223 0.0768 0.0768
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0188 0.0589 0.0579
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0112 0.0207 0.0192
Entamoeba histolytica SH2-protein kinase domain containing protein 0.01 0.0142 0.0624
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0188 0.0589 0.0543
Echinococcus multilocularis mitogen activated protein kinase 11 0.0158 0.0438 0.0438
Schistosoma mansoni protein kinase 0.0233 0.082 0.082
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0455 0.1947 0.1947
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0188 0.0589 0.169
Plasmodium falciparum protein kinase 5 0.0118 0.0238 0.0189
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0707 0.3228 0.3194
Loa Loa (eye worm) hypothetical protein 0.0302 0.117 0.1156
Giardia lamblia High cysteine protein 0.0206 0.0683 0.1966
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0361 0.1467 0.1467
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0118 0.0238 0.0189
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0061 0.0049
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0101 0.0149 0.0126
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Entamoeba histolytica protein kinase, putative 0.0086 0.0075 0.033
Giardia lamblia Kinase, NEK 0.0135 0.0324 0.0831
Schistosoma mansoni notch 0.0206 0.0683 0.0683
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0188 0.0589 0.169
Echinococcus granulosus Glutaredoxin protein 5 0.0121 0.0249 0.0249
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0188 0.0589 0.0568
Entamoeba histolytica protein kinase, putative 0.0128 0.0287 0.1257
Schistosoma mansoni serine/threonine protein kinase 0.0293 0.1124 0.1124
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0209 0.0209
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Brugia malayi Protein kinase domain containing protein 0.044 0.1873 0.1854
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0238 0.0583
Trypanosoma cruzi polo-like protein kinase, putative 0.0266 0.0989 0.0979
Echinococcus multilocularis dual specificity protein kinase clk2 0.0152 0.0411 0.0411
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0064 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.072 0.072
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0109 0.019 0.0179
Echinococcus multilocularis growth factor receptor bound protein 2 0.009 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0101 0.0149 0.0134
Loa Loa (eye worm) hypothetical protein 0.0371 0.1521 0.1509
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.3194
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0707 0.3228 1
Echinococcus granulosus casein kinase I delta 0.0109 0.0188 0.0188
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Echinococcus granulosus tyrosine protein kinase 0.0281 0.1062 0.1062
Plasmodium falciparum calcium-dependent protein kinase 1 0.0101 0.0149 0.01
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0707 0.3228 0.3212
Echinococcus multilocularis mitogen activated protein kinase 3 0.0084 0.0064 0.0064
Schistosoma mansoni vesicular amine transporter 0.0371 0.1521 0.1521
Toxoplasma gondii rhoptry neck protein RON1 0.0381 0.157 0.1528
Brugia malayi basement membrane proteoglycan 0.0112 0.0207 0.0184
Echinococcus multilocularis expressed protein 0.0084 0.0061 0.0061
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0188 0.0589 0.1455
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0707 0.3228 0.3228
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Echinococcus granulosus nephrin 0.011 0.0197 0.0197
Loa Loa (eye worm) gastrulation defective protein 1 0.066 0.2986 0.2976
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0223 0.0768 0.0768
Trichomonas vaginalis glutamate synthase, putative 0.0188 0.0589 0.169
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0078 0.0033 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Giardia lamblia Kinase, CMGC GSK 0.0128 0.0287 0.0714
Onchocerca volvulus 0.0381 0.157 0.8229
Brugia malayi Variant SH3 domain containing protein 0.0094 0.0113 0.009
Onchocerca volvulus 0.032 0.1261 0.6599
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0112 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.009 0.0092 0.0077
Brugia malayi GCC2 and GCC3 family protein 0.0587 0.2617 0.26
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Entamoeba histolytica protein kinase, putative 0.0287 0.1095 0.48
Echinococcus granulosus growth factor receptor bound protein 2 0.0092 0.0104 0.0104
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0068 0.0057
Echinococcus multilocularis myosin iiia 0.0085 0.0068 0.0068
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0188 0.0589 0.0589
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0588 0.2624 0.2613
Onchocerca volvulus 0.0381 0.157 0.8229
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.072 0.072
Trypanosoma brucei SNF1-related protein kinases, putative 0.009 0.0092 0.0043
Plasmodium falciparum thioredoxin reductase 0.0707 0.3228 0.3194
Echinococcus granulosus raf serine:threonine protein kinase 0.0088 0.0081 0.0081
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0223 0.0768 0.0768
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0519 0.2274 0.2257
Echinococcus multilocularis tyrosine protein kinase Srms 0.0186 0.0578 0.0578
Trichomonas vaginalis STE family protein kinase 0.0135 0.0324 0.0854
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0238 0.0238
Schistosoma mansoni glutamate synthase 0.0188 0.0589 0.0589
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0135 0.0324 0.0276
Brugia malayi Calcium binding EGF domain containing protein 0.0206 0.0683 0.0662
Giardia lamblia Kinase, CMGC GSK 0.0128 0.0287 0.0714
Echinococcus multilocularis casein kinase I delta 0.0109 0.0188 0.0188
Brugia malayi Protein kinase domain containing protein 0.0694 0.3162 0.3147
Echinococcus multilocularis protein jagged 1 0.0206 0.0683 0.0683
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0188 0.0589 0.2584
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0396 0.1647 0.1647
Leishmania major NADH dehydrogenase, putative 0.0188 0.0589 0.0543
Loa Loa (eye worm) TK/FER protein kinase 0.0396 0.1647 0.1634
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0152 0.0411 0.0363
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0223 0.0768 0.0768
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0061 0.0012
Brugia malayi EGF-like domain containing protein 0.0206 0.0683 0.0662
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0223 0.0768 0.0768
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0064 0.0052
Echinococcus granulosus expressed protein 0.0084 0.0061 0.0061
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0138 0.0338 0.0323
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0188 0.0589 0.1455
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0238 0.0238
Echinococcus granulosus tyrosine protein kinase Fyn 0.0223 0.0768 0.0768
Schistosoma mansoni hypothetical protein 0.0112 0.0207 0.0207
Plasmodium falciparum glutathione reductase 0.0707 0.3228 0.3194
Schistosoma mansoni cell adhesion molecule 0.0223 0.0768 0.0768
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0707 0.3228 0.3193
Brugia malayi protein unc-22 0.0145 0.0373 0.0351
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0188 0.0589 0.2584
Entamoeba histolytica protein kinase, putative 0.0088 0.0081 0.0356
Giardia lamblia Kinase, CMGC CDK 0.0118 0.0238 0.0559
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Onchocerca volvulus 0.0381 0.157 0.8229
Schistosoma mansoni serine/threonine protein kinase 0.0387 0.1603 0.1603
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0152 0.0411 0.0363
Echinococcus granulosus mitogen activated protein kinase 0.0084 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0082 0.0053 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0064 0.0052
Echinococcus multilocularis tyrosine protein kinase ABL1 0.01 0.0142 0.0142
Trichomonas vaginalis STE family protein kinase 0.0086 0.0075 0.0071
Onchocerca volvulus 0.011 0.0197 0.0981
Echinococcus granulosus casein kinase I gamma 0.0211 0.0706 0.0706
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0094 0.0113 0.0113
Echinococcus multilocularis Immunoglobulin 0.0112 0.0207 0.0207
Brugia malayi protein kinase C3,putative 0.0156 0.0431 0.0409
Trichomonas vaginalis AGC family protein kinase 0.0195 0.0627 0.1809
Echinococcus multilocularis tyrosine protein kinase shark 0.0308 0.1201 0.1201
Trypanosoma brucei rac serine-threonine kinase, putative 0.0296 0.1139 0.1095
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0338 0.0898
Loa Loa (eye worm) hypothetical protein 0.0579 0.2575 0.2564
Schistosoma mansoni serine/threonine protein kinase 0.0266 0.0989 0.0989
Loa Loa (eye worm) hypothetical protein 0.0207 0.069 0.0676
Loa Loa (eye worm) hypothetical protein 0.0099 0.0141 0.0127
Plasmodium falciparum serine/threonine protein kinase, putative 0.0145 0.037 0.0322
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0188 0.0589 0.0542
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0135 0.0324 0.0275
Schistosoma mansoni tyrosine kinase 0.0308 0.1201 0.1201
Brugia malayi Protein kinase domain containing protein 0.0361 0.1467 0.1448
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.069 0.0669
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0095 0.012 0.0105
Trichomonas vaginalis STE family protein kinase 0.0086 0.0075 0.0071
Schistosoma mansoni cell adhesion molecule 0.0207 0.069 0.069
Trypanosoma brucei protein kinase, putative 0.0128 0.0287 0.0239
Brugia malayi Protein kinase domain containing protein 0.0191 0.0605 0.0583
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0223 0.0768 0.0754
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0112 0.0207 0.0207
Brugia malayi Animal haem peroxidase family protein 0.0095 0.012 0.0097
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0094 0.0113 0.0113
Echinococcus granulosus cyclin dependent kinase 1 0.0118 0.0238 0.0238
Brugia malayi Protein kinase domain containing protein 0.0082 0.0053 0.003
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Onchocerca volvulus Netrin receptor homolog 0.0123 0.0263 0.1328
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0213 0.072 0.072
Entamoeba histolytica protein kinase 2, putative 0.0155 0.0425 0.1865
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Echinococcus granulosus peroxidasin 0.0208 0.0691 0.0691
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0188 0.0589 0.169
Onchocerca volvulus Serine\/threonine kinase homolog 0.0163 0.0462 0.2382
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0145 0.037 0.1623
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0206 0.0683 0.0683
Loa Loa (eye worm) casein kinase 0.0176 0.053 0.0516
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0186 0.0578 0.0578
Brugia malayi Immunoglobulin domain containing protein 0.0112 0.0207 0.0184
Trichomonas vaginalis STE family protein kinase 0.0085 0.0068 0.005
Toxoplasma gondii AGC kinase 0.0113 0.0209 0.0161
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0229 0.08 0.0786
Echinococcus granulosus Vam6:Vps39 protein 0.0109 0.019 0.019
Plasmodium vivax thioredoxin reductase, putative 0.204 1 1
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0198 0.0644 0.063
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.0644 0.0644
Echinococcus multilocularis glutamate synthase 0.0188 0.0589 0.0589
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Trichomonas vaginalis AGC family protein kinase 0.0135 0.0324 0.0854
Schistosoma mansoni serine/threonine-protein kinase 0.0164 0.047 0.047
Brugia malayi Leucine Rich Repeat family protein 0.0095 0.0121 0.0098
Loa Loa (eye worm) hypothetical protein 0.0483 0.2092 0.208
Mycobacterium ulcerans NADH dehydrogenase 0.0188 0.0589 0.1455
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.0188 0.0425
Echinococcus multilocularis aurora kinase A 0.0145 0.037 0.037
Schistosoma mansoni hypothetical protein 0.0095 0.012 0.012
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0707 0.3228 0.2803
Schistosoma mansoni tyrosine kinase 0.024 0.0856 0.0856
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0219 0.0751 0.0751
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0223 0.0768 0.0768
Loa Loa (eye worm) TK/ROR protein kinase 0.0142 0.0357 0.0342
Brugia malayi C1-like domain containing protein 0.0215 0.0728 0.0707
Echinococcus multilocularis c src tyrosine kinase 0.0137 0.0331 0.0331
Trypanosoma cruzi Protein kinase B 0.0164 0.047 0.0459
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0219 0.0525
Loa Loa (eye worm) hypothetical protein 0.0579 0.2575 0.2564
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0188 0.0589 0.0589
Brugia malayi Protein kinase domain containing protein 0.0588 0.2624 0.2607
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0123 0.0261 0.0247
Brugia malayi EGF-like domain containing protein 0.0206 0.0683 0.0662
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0188 0.0589 0.0543
Loa Loa (eye worm) TK/ABL protein kinase 0.01 0.0142 0.0127
Trypanosoma brucei protein kinase, putative 0.0084 0.0064 0.0015
Onchocerca volvulus 0.0206 0.0683 0.3548
Brugia malayi Prion-like- 0.0095 0.012 0.0097
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0899 0.0899
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.0238 0.0223
Echinococcus multilocularis lachesin 0.0207 0.069 0.069
Schistosoma mansoni tyrosine kinase 0.044 0.1869 0.1869
Echinococcus granulosus serine:threonine protein kinase N2 0.0127 0.0279 0.0279
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0188 0.0589 0.169
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Schistosoma mansoni ste20-related kinase 0.0203 0.0666 0.0666
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0188 0.0589 0.0543
Onchocerca volvulus 0.011 0.0197 0.0981
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0223 0.0768 0.0768
Onchocerca volvulus 0.0095 0.012 0.0571
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0226 0.0786 0.0786
Echinococcus multilocularis Immunoglobulin 0.0112 0.0207 0.0207
Loa Loa (eye worm) camk/dcamkl protein kinase 0.015 0.0397 0.0382
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0198 0.0644 0.0644
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.034 0.1362 0.1349
Loa Loa (eye worm) hypothetical protein 0.0109 0.019 0.0175
Brugia malayi Cadherin domain containing protein 0.0206 0.0683 0.0662
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Echinococcus multilocularis peroxidasin 0.0208 0.0691 0.0691
Onchocerca volvulus 0.0206 0.0683 0.3548
Echinococcus multilocularis 0.0118 0.0235 0.0235
Schistosoma mansoni serine/threonine kinase 0.0214 0.0725 0.0725
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0188 0.0589 0.0579
Schistosoma mansoni hypothetical protein 0.0112 0.0207 0.0207
Trichomonas vaginalis glutamate synthase, putative 0.0188 0.0589 0.169
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0142 0.0357 0.0357
Echinococcus granulosus roundabout 2 0.0594 0.2653 0.2653
Onchocerca volvulus 0.01 0.0142 0.0691
Giardia lamblia Kinase, CMGC CK2 0.01 0.0145 0.0266
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0387 0.1603 0.1603
Loa Loa (eye worm) variant SH3 domain-containing protein 0.009 0.0094 0.0079
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0163 0.0462 0.0462
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0707 0.3228 1
Onchocerca volvulus 0.01 0.0142 0.0691
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0142 0.0357 0.0357
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0707 0.3228 1
Echinococcus multilocularis serine:threonine protein kinase 38 0.0166 0.0481 0.0481
Brugia malayi basement membrane proteoglycan precursor 0.0112 0.0207 0.0184
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0188 0.0188
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0238 0.0583
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.045 0.1924 0.1912
Brugia malayi Immunoglobulin I-set domain containing protein 0.0223 0.0768 0.0747
Echinococcus multilocularis Immunoglobulin 0.0371 0.1521 0.1521
Brugia malayi Protein kinase domain containing protein 0.0192 0.0609 0.0588
Trichomonas vaginalis AGC family protein kinase 0.0145 0.037 0.1
Echinococcus granulosus protein tyrosine kinase 0.0541 0.2383 0.2383
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.069 0.0669
Giardia lamblia Kinase, CMGC CLK 0.0152 0.0411 0.1105
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0188 0.0589 0.169
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Echinococcus granulosus basement membrane specific heparan sulfate 0.0112 0.0207 0.0207
Leishmania major protein kinase, putative 0.0145 0.037 0.0322
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.024 0.0856 0.0856
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0381 0.157 0.1557
Leishmania major hypothetical protein, conserved 0.0188 0.0589 0.0543
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0158 0.0438 0.039
Schistosoma mansoni adapter molecule crk 0.009 0.0094 0.0094
Onchocerca volvulus 0.0381 0.157 0.8229
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0166 0.0481 0.0481
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0707 0.3228 0.3194
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Schistosoma mansoni hypothetical protein 0.0095 0.012 0.012
Brugia malayi Casein kinase II, alpha chain 0.01 0.0145 0.0123
Schistosoma mansoni tyrosine kinase 0.0137 0.0331 0.0331
Schistosoma mansoni nephrin related 0.0112 0.0207 0.0207
Schistosoma mansoni hypothetical protein 0.0112 0.0207 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.0694 0.3162 0.3162
Entamoeba histolytica PH domain containing protein kinase, putative 0.0122 0.0254 0.1112
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.009 0.0094 0.0094
Trypanosoma brucei cdc2-related kinase 3 0.0118 0.0238 0.0189
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.0053 0.0038
Loa Loa (eye worm) AUR protein kinase 0.0145 0.037 0.0356
Giardia lamblia Kinase, CDC7 0.009 0.0094 0.0104
Onchocerca volvulus 0.0135 0.0324 0.1653
Trypanosoma cruzi casein kinase, putative 0.0109 0.0188 0.0176
Schistosoma mansoni protein kinase 0.0152 0.0408 0.0408
Loa Loa (eye worm) hypothetical protein 0.0176 0.0532 0.0517
Loa Loa (eye worm) hypothetical protein 0.0116 0.0226 0.0211
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Onchocerca volvulus 0.01 0.0142 0.0691
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0109 0.019 0.019
Schistosoma mansoni tyrosine kinase 0.0395 0.1643 0.1643
Echinococcus multilocularis fat cadherin tumor suppressor 0.0206 0.0683 0.0683
Onchocerca volvulus 0.0381 0.157 0.8229
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0184 0.057 0.057
Echinococcus granulosus homeodomain interacting protein kinase 3 0.02 0.0653 0.0653
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0707 0.3228 0.3194
Brugia malayi hypothetical protein 0.0112 0.0207 0.0184
Onchocerca volvulus Putative cubilin 0.0206 0.0683 0.3548
Echinococcus granulosus delta-like protein 1 0.0206 0.0683 0.0683
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0121 0.0249 0.0249
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.011 0.0197 0.0182
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.0238 0.0238
Brugia malayi Protein kinase domain containing protein 0.0187 0.0585 0.0564
Schistosoma mansoni protein kinase 0.0361 0.1467 0.1467
Loa Loa (eye worm) hypothetical protein 0.0226 0.0786 0.0772
Brugia malayi serine/threonine-protein kinase PAK 7 0.0229 0.08 0.0779
Trypanosoma brucei trypanothione reductase 0.204 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0338 0.0898
Brugia malayi RhoGAP domain containing protein 0.0094 0.0113 0.009
Giardia lamblia Glutamate synthase 0.0188 0.0589 0.1669
Echinococcus multilocularis titin 0.0095 0.012 0.012
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0347 0.1397 0.1397
Leishmania major protein kinase A catalytic subunit isoform 2 0.0113 0.0209 0.0161
Echinococcus granulosus dual specificity 0.0138 0.0338 0.0338
Loa Loa (eye worm) hypothetical protein 0.0234 0.0825 0.0811
Plasmodium vivax serine/threonine kinase-1, putative 0.0152 0.0411 0.0362
Loa Loa (eye worm) AUR protein kinase 0.0145 0.037 0.0356
Leishmania major protein kinase, putative 0.0085 0.0068 0.0019
Schistosoma mansoni titin 0.0095 0.012 0.012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.069 0.0669
Echinococcus granulosus Immunoglobulin 0.0371 0.1521 0.1521
Echinococcus granulosus low density lipoprotein receptor ldl 0.0112 0.0207 0.0207
Schistosoma mansoni tyrosine kinase 0.0254 0.0927 0.0927
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0188 0.0589 0.0543
Trypanosoma brucei casein kinase I, isoform 2 0.0109 0.0188 0.0139
Brugia malayi Protein kinase domain containing protein 0.0118 0.0238 0.0215
Echinococcus multilocularis c4b binding protein beta chain 0.0381 0.157 0.157
Schistosoma mansoni tyrosine kinase 0.0362 0.1475 0.1475
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0481 0.135
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.0238 0.0227
Echinococcus multilocularis c Jun NH2 terminal kinase 0.026 0.0959 0.0959
Brugia malayi kettin 0.0095 0.012 0.0097
Loa Loa (eye worm) hypothetical protein 0.0109 0.019 0.0175
Echinococcus granulosus twitchin 0.0501 0.2181 0.2181
Onchocerca volvulus 0.0188 0.0589 0.3052
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0101 0.0149 0.0149
Schistosoma mansoni netrin receptor unc5 0.0141 0.035 0.035
Schistosoma mansoni vam6/vps39 related 0.0109 0.019 0.019
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0084 0.0061 0.0012
Loa Loa (eye worm) hypothetical protein 0.0371 0.1521 0.1509
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0223 0.0768 0.0768
Schistosoma mansoni protein kinase 0.01 0.0145 0.0145
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0397 0.1654 0.1654
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0152 0.0408 0.0394
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0128 0.0287 0.0287
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0371 0.1521 0.1521
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0128 0.0287 0.0239
Toxoplasma gondii EGF family domain-containing protein 0.0206 0.0683 0.0637
Giardia lamblia Kinase, CMGC DYRK 0.0138 0.0338 0.0875
Loa Loa (eye worm) SRC-1 0.0223 0.0768 0.0754
Loa Loa (eye worm) hypothetical protein 0.0112 0.0207 0.0192
Schistosoma mansoni serine/threonine protein kinase 0.026 0.0959 0.0959
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0094 0.0129
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0118 0.0238 0.0189
Echinococcus granulosus rho-associated protein kinase 1 0.032 0.1261 0.1261
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.009 0.0092 0.0077
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0188 0.0589 0.0542
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0188 0.0589 0.0589
Brugia malayi Variant SH3 domain containing protein 0.009 0.0094 0.0072
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0188 0.0589 0.169
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0209 0.0493
Loa Loa (eye worm) hypothetical protein 0.0386 0.1599 0.1586
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0084 0.0064 0.0049
Brugia malayi hypothetical protein 0.0109 0.019 0.0168
Echinococcus multilocularis casein kinase i 0.0109 0.0188 0.0188
Brugia malayi Temporarily assigned gene name protein 59 0.0126 0.0276 0.0254
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0138 0.0338 0.029
Brugia malayi Protein kinase domain containing protein 0.0547 0.2413 0.2396
Echinococcus granulosus neurogenic locus notch protein 0.0206 0.0683 0.0683
Echinococcus multilocularis serine:threonine kinase SAD 1 0.009 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Brugia malayi Protein kinase domain containing protein 0.01 0.0142 0.012
Schistosoma mansoni hypothetical protein 0.0112 0.0207 0.0207
Trypanosoma brucei hypothetical protein, conserved 0.0188 0.0589 0.0543
Brugia malayi Protein kinase domain containing protein 0.044 0.1869 0.185
Echinococcus granulosus tyrosine kinase 0.01 0.0142 0.0142
Schistosoma mansoni protein kinase 0.0145 0.037 0.037
Giardia lamblia Kinase, AGC PKA 0.0155 0.0425 0.1151
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0481 0.0481
Echinococcus multilocularis Glutaredoxin protein 5 0.0121 0.0249 0.0249
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0088 0.0081 0.0356
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Schistosoma mansoni septate junction protein 0.0207 0.069 0.069
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0317 0.0317
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0134 0.0316 0.0316
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0122 0.0255 0.0244
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Brugia malayi Protein kinase domain containing protein 0.01 0.0142 0.012
Echinococcus multilocularis titin 0.0145 0.0373 0.0373
Onchocerca volvulus 0.009 0.0094 0.0436
Echinococcus multilocularis protein kinase shaggy 0.0128 0.0287 0.0287
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0338 0.0898
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Loa Loa (eye worm) thioredoxin reductase 0.204 1 1
Schistosoma mansoni neuroglian 0.0223 0.0768 0.0768
Schistosoma mansoni slit 0.0206 0.0685 0.0685
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.011 0.0197 0.0197
Schistosoma mansoni titin 0.011 0.0197 0.0197
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0197 0.0175
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0922 0.432 0.4311
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0249 0.0899 0.0899
Onchocerca volvulus 0.0381 0.157 0.8229
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Schistosoma mansoni tyrosine kinase 0.0348 0.1406 0.1406
Brugia malayi Protein kinase domain containing protein 0.01 0.0142 0.012
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Brugia malayi Protein kinase domain containing protein 0.0152 0.0411 0.0389
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0325 0.1288 0.1268
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0197 0.0175
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0128 0.0287 0.0287
Trichomonas vaginalis STE family protein kinase 0.0086 0.0075 0.0071
Loa Loa (eye worm) hypothetical protein 0.0207 0.069 0.0676
Echinococcus granulosus tyrosine protein kinase Blk 0.0186 0.0578 0.0578
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0197 0.0175
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0149 0.0149
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0707 0.3228 0.3194
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0068 0.0057
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0109 0.019 0.019
Trypanosoma brucei Casein kinase II 0.01 0.0145 0.0096
Plasmodium falciparum calcium-dependent protein kinase 3 0.0101 0.0149 0.01
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0215 0.0728 0.0707
Echinococcus granulosus dual specificity 0.0138 0.0338 0.0338
Echinococcus multilocularis serine:threonine protein kinase N2 0.0127 0.0279 0.0279
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0113 0.0209 0.0161
Plasmodium falciparum serine/threonine protein kinase 0.0084 0.0061 0.0012
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0109 0.019 0.0179
Echinococcus multilocularis notch 0.0206 0.0683 0.0683
Echinococcus granulosus serine:threonine protein kinase N2 0.0293 0.1124 0.1124
Brugia malayi probable protein kinase 0.0261 0.0962 0.0942
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0387 0.1603 0.1603
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0145 0.0291
Entamoeba histolytica protein kinase, putative 0.0133 0.0309 0.1357
Echinococcus granulosus hemicentin 1 0.0207 0.069 0.069
Loa Loa (eye worm) hypothetical protein 0.0095 0.012 0.0105
Loa Loa (eye worm) hypothetical protein 0.0381 0.157 0.1557
Loa Loa (eye worm) one IG domain family member 0.0095 0.012 0.0105
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.069 0.0669
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.322
Entamoeba histolytica protein kinase domain containing protein 0.0145 0.037 0.1623
Leishmania major protein kinase A catalytic subunit isoform 1 0.0113 0.0209 0.0161
Echinococcus granulosus tyrosine protein kinase Src42A 0.0223 0.0768 0.0768
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0149 0.0149
Brugia malayi Immunoglobulin domain containing protein 0.0112 0.0207 0.0184
Trypanosoma cruzi SNF1-related protein kinases, putative 0.009 0.0092 0.0081
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0163 0.0462 0.0462
Echinococcus multilocularis casein kinase I alpha 0.0109 0.0188 0.0188
Schistosoma mansoni notch 0.0206 0.0683 0.0683
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0095 0.012 0.012
Onchocerca volvulus Tyrosine kinase homolog 0.0447 0.1905 1
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0188 0.0589 0.169
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.0238 0.1043
Echinococcus multilocularis neurogenic locus notch protein 0.0206 0.0683 0.0683
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Echinococcus granulosus protein kinase c epsilon type 0.0208 0.0695 0.0695
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0207 0.069 0.3584
Brugia malayi EGF-like domain containing protein 0.0206 0.0683 0.0662
Trichomonas vaginalis CAMK family protein kinase 0.0266 0.0989 0.2949
Loa Loa (eye worm) animal heme peroxidase 0.0095 0.012 0.0105
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0338 0.0898
Schistosoma mansoni rap gtpase-activating protein 0.0109 0.019 0.019
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0255 0.0255
Loa Loa (eye worm) projectin 0.011 0.0197 0.0182
Schistosoma mansoni notch 0.0206 0.0683 0.0683
Echinococcus granulosus tyrosine protein kinase Src64B 0.0223 0.0768 0.0768
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0082 0.0053 0.0053
Brugia malayi Protein kinase domain containing protein 0.0122 0.0255 0.0233
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0338 0.0338
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0197 0.0175
Echinococcus multilocularis NCK adaptor protein 0.0092 0.0104 0.0104
Echinococcus granulosus serine:threonine kinase SAD 1 0.009 0.0092 0.0092
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0118 0.0238 0.0223
Entamoeba histolytica protein kinase, putative 0.0122 0.0255 0.1117
Schistosoma mansoni cell adhesion molecule 0.011 0.0197 0.0197
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0707 0.3228 0.3228
Plasmodium falciparum protein serine/threonine kinase-1 0.0152 0.0411 0.0363
Echinococcus granulosus cyclin dependent kinase 5 0.0118 0.0238 0.0238
Entamoeba histolytica thioredoxin reductase, putative 0.0188 0.0589 0.2584
Loa Loa (eye worm) TK/EGFR protein kinase 0.0598 0.2675 0.2664
Loa Loa (eye worm) hypothetical protein 0.0207 0.069 0.0676
Echinococcus granulosus Protein kinase C brain isozyme 0.0247 0.0892 0.0892
Brugia malayi Immunoglobulin I-set domain containing protein 0.0223 0.0768 0.0747
Echinococcus granulosus down syndrome cell adhesion 0.0095 0.012 0.012
Trichomonas vaginalis AGC family protein kinase 0.0145 0.037 0.1
Entamoeba histolytica cyclin C, putative 0.0521 0.2281 1
Echinococcus granulosus c4b binding protein beta chain 0.0381 0.157 0.157
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0166 0.0481 0.0481
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0152 0.0411 0.0363
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.0238 0.0223
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0197 0.0175
Echinococcus granulosus tyrosine kinase 0.0186 0.0578 0.0578
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.0338 0.0898
Entamoeba histolytica protein kinase, putative 0.0296 0.1139 0.4994
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0092 0.0081
Onchocerca volvulus 0.01 0.0142 0.0691
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0145 0.037 0.0321
Loa Loa (eye worm) hypothetical protein 0.01 0.0142 0.0127
Echinococcus multilocularis protein kinase c epsilon type 0.0208 0.0695 0.0695
Schistosoma mansoni hypothetical protein 0.0206 0.0683 0.0683
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0092 0.0043
Brugia malayi Thioredoxin reductase 0.204 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0064 0.0035
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0188 0.0589 0.0568
Schistosoma mansoni hypothetical protein 0.0109 0.019 0.019
Brugia malayi Disorganized muscle protein 1 0.0095 0.012 0.0097
Schistosoma mansoni cell adhesion molecule 0.0499 0.2169 0.2169
Plasmodium vivax apical sushi protein, putative 0.0381 0.157 0.1527
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Leishmania major protein kinase, putative 0.0152 0.0411 0.0363
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0232 0.0814 0.0814
Echinococcus granulosus protein kinase 0.0152 0.0408 0.0408
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0109 0.019 0.0142
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0347 0.1397 0.7317
Echinococcus granulosus NDR protein kinase 0.0166 0.0481 0.0481
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.044 0.1873 0.1861
Trypanosoma cruzi hypothetical protein, conserved 0.0188 0.0589 0.0579
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0207 0.0184
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0213 0.072 0.072
Echinococcus multilocularis mitogen activated protein kinase 11 0.0158 0.0438 0.0438
Schistosoma mansoni protein kinase 0.0426 0.18 0.18
Treponema pallidum NADH oxidase 0.0707 0.3228 1
Toxoplasma gondii selenide, water dikinase 0.0188 0.0589 0.0543
Brugia malayi phosphoinositide-dependent protein kinase I 0.0082 0.0053 0.003
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0707 0.3228 0.3194
Onchocerca volvulus 0.0095 0.0121 0.0579
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0188 0.0589 0.0589
Echinococcus granulosus slit 2 protein 0.0234 0.0825 0.0825
Onchocerca volvulus 0.0381 0.157 0.8229
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Echinococcus granulosus neurogenic locus protein delta 0.0206 0.0683 0.0683
Onchocerca volvulus Serine\/threonine kinase homolog 0.0266 0.0989 0.5162
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0835 0.3877 0.3868
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0188 0.0589 0.0589
Plasmodium falciparum ferrodoxin reductase-like protein 0.0188 0.0589 0.0543
Brugia malayi Sushi domain 0.0381 0.157 0.155
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0287 0.0737
Brugia malayi Protein kinase domain containing protein 0.01 0.0142 0.012
Echinococcus multilocularis casein kinase ii subunit alpha 0.01 0.0145 0.0145
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0095 0.012 0.012
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0483 0.2092 0.2092
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.0238 0.1043
Echinococcus granulosus tyrosine protein kinase shark 0.0308 0.1201 0.1201
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0207 0.069 0.069
Entamoeba histolytica protein kinase, putative 0.0138 0.0338 0.1481
Loa Loa (eye worm) hypothetical protein 0.0207 0.069 0.0676
Entamoeba histolytica serine/threonine protein kinase, putative 0.009 0.0092 0.0403
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0188 0.0589 0.0543
Loa Loa (eye worm) hypothetical protein 0.0588 0.2624 0.2613
Loa Loa (eye worm) TK protein kinase 0.0335 0.134 0.1327
Brugia malayi notch-like transmembrane receptor 0.0206 0.0683 0.0662
Loa Loa (eye worm) hypothetical protein 0.0349 0.141 0.1397
Schistosoma mansoni cell adhesion molecule 0.0112 0.0207 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.037 0.037
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0913 0.0913
Loa Loa (eye worm) programmed cell death 8 0.0188 0.0589 0.0575
Loa Loa (eye worm) hypothetical protein 0.0349 0.141 0.1397
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0209 0.0198
Onchocerca volvulus Putative titin 0.0095 0.012 0.0571
Loa Loa (eye worm) hypothetical protein 0.0087 0.0079 0.0064
Entamoeba histolytica protein kinase domain containing protein 0.0138 0.0338 0.1481
Echinococcus multilocularis Immunoglobulin 0.0371 0.1521 0.1521
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0215 0.0728 0.0714
Loa Loa (eye worm) hypothetical protein 0.0109 0.019 0.0175
Loa Loa (eye worm) hypothetical protein 0.0223 0.0768 0.0754
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0149 0.0302
Brugia malayi STE20-like kinase MST 0.0253 0.0922 0.0901
Echinococcus multilocularis tyrosine kinase 0.01 0.0142 0.0142
Schistosoma mansoni hypothetical protein 0.0099 0.0141 0.0141
Echinococcus granulosus dual specificity 0.0138 0.0338 0.0338
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0115 0.0219 0.0219
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0209 0.0209
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0347 0.1397 0.1397
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.012 0.0097
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0101 0.0149 0.01
Echinococcus multilocularis slit 2 protein 0.0234 0.0825 0.0825
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0152 0.0411 0.04
Loa Loa (eye worm) hypothetical protein 0.0112 0.0207 0.0192
Trypanosoma brucei aurora B kinase 0.0145 0.037 0.0322
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Brugia malayi protein kinase C II. 0.0208 0.0695 0.0674
Onchocerca volvulus 0.0128 0.0287 0.1454
Brugia malayi SH2 domain containing protein 0.0396 0.1647 0.1628
Schistosoma mansoni hypothetical protein 0.0112 0.0207 0.0207
Trichomonas vaginalis AGC family protein kinase 0.0296 0.1139 0.3422
Brugia malayi hypothetical protein 0.0381 0.157 0.155
Echinococcus granulosus thioredoxin glutathione reductase 0.204 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0206 0.0683 0.0669
Onchocerca volvulus 0.0095 0.012 0.0571
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0092 0.0124
Schistosoma mansoni tyrosine kinase 0.044 0.1869 0.1869
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0707 0.3228 0.322
Echinococcus multilocularis protein jagged 2 0.0206 0.0683 0.0683
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0142 0.0127
Loa Loa (eye worm) hypothetical protein 0.0113 0.0209 0.0194
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0707 0.3228 1

Activities

Activity type Activity value Assay description Source Reference
Deuterium retention (ADMET) = 58 % Compound incubated with microsomal preparations from phenobarbital treated male rats with the substrate rac 8-D and the amount of deuterium retained was reported after normal workup ChEMBL. 4020838
Deuterium retention (ADMET) = 58 % Amount of deuterium retained was reported after reincubation followed by normal workup in phenobarbital treated male rats with rac 8-D ChEMBL. 4020838
Deuterium retention (ADMET) = 76 % Amount of deuterium retained was reported after normal workup in beta-naphthoflavone-treated male rats with the substrate rac 7-D ChEMBL. 4020838
Deuterium retention (ADMET) = 76 % Compound incubated with microsomal preparations from beta-naphthoflavone-treated male rats with the substrate rac 7-D and the amount of deuterium retained was reported after reincubation followed by normal workup ChEMBL. 4020838
Deuterium retention (ADMET) = 82 % Amount of deuterium retained was reported after normal workup in rats ChEMBL. 4020838
Deuterium retention (ADMET) = 83 % Amount of deuterium retained was reported after reincubation followed by normal workup in phenobarbital treated male rats ChEMBL. 4020838
Potency (functional) 37.6858 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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