Detailed information for compound 114802

Basic information

Technical information
  • TDR Targets ID: 114802
  • Name: 8-[prop-2-enyl(propyl)amino]-6,7,8,9-tetrahyd ro-3H-benzo[e]indole-1-carbaldehyde
  • MW: 296.407 | Formula: C19H24N2O
  • H donors: 1 H acceptors: 1 LogP: 3.8 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCN(C1CCc2c(C1)c1c(C=O)c[nH]c1cc2)CC=C
  • InChi: 1S/C19H24N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h3,6,8,12-13,16,20H,1,4-5,7,9-11H2,2H3
  • InChiKey: DBGOPRYLVZPMHQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 8-[allyl(propyl)amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
  • 8-[allyl(propyl)amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carboxaldehyde
  • 8-(prop-2-enyl-propylamino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
  • 8-(allyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
  • 8-(allyl-propylamino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carboxaldehyde
  • 8-(prop-2-enyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Dopamine D2 receptor Starlite/ChEMBL References
Rattus norvegicus Dopamine D3 receptor Starlite/ChEMBL References
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_141128 All targets in OG5_141128
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum ko:K04153 5-hydroxytryptamine (serotonin) receptor 1A, putative Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor Get druggable targets OG5_141128 All targets in OG5_141128
Schistosoma mansoni biogenic amine (5HT) receptor Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus granulosus biogenic amine 5HT receptor Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum expressed protein Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum ko:K04165 Oamb gene product from transcript, putative Get druggable targets OG5_141128 All targets in OG5_141128
Schistosoma japonicum Octopamine receptor, putative Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_141128 All targets in OG5_141128
Brugia malayi Serotonin/octopamine receptor family protein 7 Get druggable targets OG5_141128 All targets in OG5_141128
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma japonicum Octopamine receptor, putative Dopamine D3 receptor   446 aa 501 aa 28.5 %
Echinococcus multilocularis neuropeptides capa receptor Serotonin 1a (5-HT1a) receptor   422 aa 430 aa 20.0 %
Onchocerca volvulus Serotonin 1a (5-HT1a) receptor   422 aa 436 aa 23.9 %
Onchocerca volvulus Dopamine D3 receptor   446 aa 462 aa 26.0 %
Schistosoma japonicum Octopamine receptor 1, putative Serotonin 1a (5-HT1a) receptor   422 aa 424 aa 24.3 %
Echinococcus multilocularis alpha 1A adrenergic receptor Dopamine D3 receptor   446 aa 473 aa 21.6 %
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor Dopamine D2 receptor   444 aa 487 aa 23.8 %
Onchocerca volvulus Glycoprotein hormone beta 5 homolog Serotonin 1a (5-HT1a) receptor   422 aa 477 aa 24.3 %
Schistosoma mansoni biogenic amine receptor Dopamine D3 receptor   446 aa 455 aa 28.6 %
Onchocerca volvulus Mitochondrial inner membrane protein homolog Serotonin 1a (5-HT1a) receptor   422 aa 383 aa 30.5 %
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Serotonin 1a (5-HT1a) receptor   422 aa 392 aa 20.7 %
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) Dopamine D3 receptor   446 aa 463 aa 25.5 %
Echinococcus multilocularis g protein coupled receptor Serotonin 1a (5-HT1a) receptor   422 aa 432 aa 23.6 %
Echinococcus multilocularis g protein coupled receptor Serotonin 1a (5-HT1a) receptor   422 aa 433 aa 22.4 %
Echinococcus multilocularis biogenic amine (5HT) receptor Dopamine D3 receptor   446 aa 499 aa 30.9 %
Onchocerca volvulus Serotonin 1a (5-HT1a) receptor   422 aa 407 aa 23.3 %
Echinococcus granulosus biogenic amine 5HT receptor Dopamine D2 receptor   444 aa 429 aa 31.7 %
Onchocerca volvulus Serotonin 1a (5-HT1a) receptor   422 aa 390 aa 33.6 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Dopamine D3 receptor   446 aa 463 aa 29.8 %
Echinococcus multilocularis serotonin receptor Dopamine D2 receptor   444 aa 428 aa 31.3 %
Onchocerca volvulus Serotonin 1a (5-HT1a) receptor   422 aa 426 aa 29.6 %
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor Serotonin 1a (5-HT1a) receptor   422 aa 350 aa 20.6 %
Brugia malayi AT19640p 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 390 aa 335 aa 21.8 %
Echinococcus granulosus alpha 1A adrenergic receptor Serotonin 1a (5-HT1a) receptor   422 aa 452 aa 21.0 %
Schistosoma japonicum ko:K04207 neuropeptide Y receptor Y5, putative Serotonin 1a (5-HT1a) receptor   422 aa 339 aa 23.0 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Serotonin 1a (5-HT1a) receptor   422 aa 448 aa 29.7 %
Loa Loa (eye worm) TYRA-2 protein Serotonin 1a (5-HT1a) receptor   422 aa 491 aa 27.3 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Serotonin 1a (5-HT1a) receptor   422 aa 410 aa 27.8 %
Schistosoma mansoni biogenic amine (dopamine) receptor Dopamine D2 receptor   444 aa 494 aa 26.3 %
Loa Loa (eye worm) hypothetical protein Serotonin 1a (5-HT1a) receptor   422 aa 388 aa 26.5 %
Schistosoma mansoni amine GPCR Serotonin 1a (5-HT1a) receptor   422 aa 440 aa 31.6 %
Echinococcus multilocularis orexin receptor type 2 Serotonin 1a (5-HT1a) receptor   422 aa 369 aa 22.2 %
Echinococcus granulosus orexin receptor type 2 Serotonin 1a (5-HT1a) receptor   422 aa 369 aa 22.0 %
Echinococcus granulosus g protein coupled receptor Serotonin 1a (5-HT1a) receptor   422 aa 432 aa 23.4 %
Echinococcus granulosus g protein coupled receptor Serotonin 1a (5-HT1a) receptor   422 aa 432 aa 24.3 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Serotonin 1a (5-HT1a) receptor   422 aa 444 aa 29.3 %
Onchocerca volvulus RB1-inducible coiled-coil protein 1 homolog Dopamine D3 receptor   446 aa 478 aa 22.8 %
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Serotonin 1a (5-HT1a) receptor   422 aa 417 aa 21.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Giardia lamblia Kinase, STE STE20 0.0206 0.0119 0.2778
Schistosoma mansoni tyrosine kinase 0.0431 0.0333 0.3335
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0104 0.0023 0.0132
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0605 0.0498 0.1837
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0104 0.0023 0.0078
Onchocerca volvulus Netrin receptor homolog 0.0098 0.0017 0.014
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Trypanosoma brucei NIMA-related protein kinase 0.01 0.0019 0.0341
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0356 0.0262 0.1878
Brugia malayi cell division control protein 2 homolog 0.0264 0.0174 0.0627
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0171 0.2938
Trypanosoma cruzi polo-like protein kinase, putative 0.0499 0.0397 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0115 0.0034 0.0118
Onchocerca volvulus 0.0197 0.0111 0.0896
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0096 0.0015 0.0088
Loa Loa (eye worm) hypothetical protein 0.0259 0.017 0.0628
Echinococcus granulosus tensin 0.0104 0.0023 0.0132
Echinococcus multilocularis tyrosine protein kinase Srms 0.0356 0.0262 0.1878
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0104 0.2251
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.016 0.0076 0.0277
Schistosoma mansoni serine/threonine protein kinase 0.0981 0.0853 0.866
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0408 0.0311 0.1842
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0115 0.0034 0.0237
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0018 0.0128
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Trichomonas vaginalis CMGC family protein kinase 0.0408 0.0311 0.6882
Loa Loa (eye worm) TK/FER protein kinase 0.0197 0.0111 0.0405
Onchocerca volvulus 0.0226 0.0139 0.1123
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0636 0.0527 0.196
Toxoplasma gondii AGC kinase 0.0251 0.0162 0.3662
Brugia malayi Immunoglobulin I-set domain containing protein 0.0142 0.0059 0.0197
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0261 0.0171 0.0633
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0251 0.0162 0.4004
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0264 0.0174 0.0643
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0093 0.0012 0.0068
Entamoeba histolytica ankyrin repeat protein 0.0093 0.0012 0.0172
Loa Loa (eye worm) hypothetical protein 0.0655 0.0545 0.2029
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0171 0.0086 0.2574
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0012 0.0173
Entamoeba histolytica protein kinase, putative 0.0206 0.0119 0.203
Schistosoma mansoni serine/threonine protein kinase 0.0533 0.0429 0.4321
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0155 0.0072 0.212
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0164 0.1612
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0282 0.0192 0.4212
Brugia malayi WH1 domain containing protein 0.0098 0.0017 0.0039
Plasmodium vivax casein kinase 1, putative 0.0206 0.0119 0.3618
Schistosoma mansoni protein kinase 0.0206 0.0119 0.115
Trichomonas vaginalis AGC family protein kinase 0.0554 0.0449 1
Schistosoma mansoni protein kinase 0.0206 0.0119 0.115
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0823 0.0704 0.2623
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0115 0.0034 0.0237
Brugia malayi Protein kinase domain containing protein 0.0528 0.0425 0.1565
Echinococcus granulosus nervana 2 0.0225 0.0137 0.0811
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0086 0.0812
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.01 0.0019 0.0386
Brugia malayi Guanylyl cyclase protein 23 0.0096 0.0016 0.0034
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0137 0.0054 0.0384
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus multilocularis casein kinase I delta 0.0206 0.0119 0.0852
Onchocerca volvulus 0.0096 0.0016 0.0127
Plasmodium vivax serine/threonine protein kinase, putative 0.0159 0.0075 0.2233
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Leishmania major protein kinase, putative 0.0343 0.0249 0.6234
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0206 0.0119 0.2923
Entamoeba histolytica PH domain containing protein kinase, putative 0.0084 0.0004 0.0039
Echinococcus multilocularis mitogen activated protein kinase 14 0.0297 0.0206 0.1476
Schistosoma mansoni tyrosine kinase 0.0648 0.0538 0.5439
Echinococcus multilocularis expressed conserved protein 0.0253 0.0164 0.1173
Schistosoma mansoni hypothetical protein 0.0226 0.0139 0.135
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0488 0.0387 0.2776
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0404 0.0307 0.1138
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Loa Loa (eye worm) TK/FER protein kinase 0.0748 0.0633 0.2356
Toxoplasma gondii NEK kinase 0.01 0.0019 0.0353
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0443 0.0344 0.2469
Schistosoma mansoni serine/threonine protein kinase 0.0458 0.0359 0.3601
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0171 0.0086 0.208
Plasmodium falciparum casein kinase 1 0.0206 0.0119 0.3618
Brugia malayi Variant SH3 domain containing protein 0.0123 0.004 0.0127
Brugia malayi casein kinase I 0.0206 0.0119 0.0421
Loa Loa (eye worm) hypothetical protein 0.0226 0.0139 0.051
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.01 0.0019 0.0341
Plasmodium falciparum serine/threonine protein kinase KIN 0.0171 0.0086 0.2574
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.023 0.0143 0.3518
Giardia lamblia Kinase, CMGC SRPK 0.0159 0.0075 0.164
Echinococcus granulosus Protein kinase C brain isozyme 0.0464 0.0364 0.2156
Schistosoma mansoni tyrosine kinase 0.0093 0.0012 0.0055
Schistosoma mansoni hypothetical protein 0.0098 0.0017 0.0107
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0466 0.0366 0.217
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0093 0.0012 0.0172
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus multilocularis mitogen activated protein kinase 14 0.0297 0.0206 0.1476
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0328 0.0235 0.0869
Loa Loa (eye worm) hypothetical protein 0.1098 0.0965 0.3597
Brugia malayi MH2 domain containing protein 0.0116 0.0034 0.0104
Echinococcus granulosus serine:threonine protein kinase 0.0216 0.0129 0.076
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0191 0.0106 0.0624
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.001 0.0035
Echinococcus granulosus roundabout 2 0.0115 0.0034 0.0196
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0217 0.013 0.0932
Loa Loa (eye worm) hypothetical protein 0.0087 0.0007 0.0017
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0313 0.0221 0.1585
Echinococcus granulosus casein kinase I alpha 0.0206 0.0119 0.0704
Plasmodium falciparum serine/threonine protein kinase, putative 0.042 0.0322 1
Echinococcus granulosus expressed conserved protein 0.0093 0.0013 0.0072
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0464 0.0364 0.2608
Schistosoma mansoni tyrosine kinase 0.0271 0.0181 0.1787
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1098 0.0965 0.3597
Loa Loa (eye worm) hypothetical protein 0.0093 0.0012 0.0037
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0226 0.0139 0.135
Brugia malayi Protein kinase domain 0.0206 0.0119 0.0421
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0091 0.001 0.0058
Onchocerca volvulus 0.0252 0.0163 0.1321
Loa Loa (eye worm) TK/FER protein kinase 0.0093 0.0012 0.0037
Entamoeba histolytica serine/threonine kinase, putative 0.0093 0.0012 0.0172
Loa Loa (eye worm) hypothetical protein 0.0185 0.01 0.0365
Schistosoma mansoni serine/threonine RGC 0.0093 0.0012 0.0055
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0034 0.0121
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0264 0.0174 0.0643
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0261 0.0171 0.4251
Entamoeba histolytica protein kinase, putative 0.0166 0.0082 0.1382
Schistosoma mansoni hypothetical protein 0.0171 0.0086 0.0815
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0191 0.0106 0.2279
Brugia malayi P38 map kinase family protein 2 0.0297 0.0206 0.0746
Brugia malayi hypothetical protein 0.0197 0.0111 0.0389
Loa Loa (eye worm) hypothetical protein 0.0116 0.0034 0.0121
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0093 0.0012 0.0172
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.016 0.0076 0.1617
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Plasmodium vivax glycogen synthase kinase 3, putative 0.0408 0.0311 0.9647
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Loa Loa (eye worm) hypothetical protein 0.0252 0.0163 0.0602
Trichomonas vaginalis CAMK family protein kinase 0.0217 0.013 0.283
Echinococcus multilocularis NCK adaptor protein 0.0182 0.0097 0.0693
Echinococcus granulosus calcium dependent protein kinase 0.0123 0.0041 0.0241
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.001 0.0013
Echinococcus granulosus mitogen activated protein kinase 3 0.016 0.0076 0.045
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0108 0.0026 0.009
Brugia malayi Protein kinase domain containing protein 0.0396 0.0299 0.1095
Loa Loa (eye worm) hypothetical protein 0.0104 0.0023 0.0078
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0122 0.0039 0.0791
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0343 0.0249 0.5505
Echinococcus granulosus calcium activated potassium channel 0.0258 0.0169 0.0999
Echinococcus granulosus signal transduction protein lnk realted 0.0104 0.0023 0.0132
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.023 0.0143 0.0525
Brugia malayi C1-like domain containing protein 0.0404 0.0307 0.1123
Echinococcus granulosus geminin 0.0171 0.0086 0.0509
Giardia lamblia Kinase, CAMK CAMKL 0.0171 0.0086 0.1921
Echinococcus granulosus NCK adaptor protein 0.0179 0.0094 0.0552
Trypanosoma cruzi casein kinase II, putative 0.019 0.0104 0.2549
Brugia malayi Immunoglobulin I-set domain containing protein 0.0115 0.0034 0.0101
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0453 0.0353 0.2095
Echinococcus multilocularis CDC7 cell division cycle 7 0.0224 0.0136 0.0975
Onchocerca volvulus 0.0259 0.017 0.1378
Brugia malayi probable protein kinase 0.0568 0.0463 0.1707
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Loa Loa (eye worm) hypothetical protein 0.0435 0.0337 0.1251
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Entamoeba histolytica hypothetical protein 0.023 0.0143 0.2438
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0206 0.0119 0.0851
Loa Loa (eye worm) hypothetical protein 0.0217 0.013 0.0478
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0093 0.0012 0.0037
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0458 0.0359 0.2573
Echinococcus multilocularis rac serine:threonine kinase 0.0309 0.0217 0.1556
Loa Loa (eye worm) TK protein kinase 0.0252 0.0163 0.0603
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0533 0.0429 0.1582
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0161 0.0077 0.184
Brugia malayi P21-Rho-binding domain containing protein 0.0098 0.0017 0.0039
Brugia malayi SH2 domain containing protein 0.0104 0.0023 0.0061
Giardia lamblia Kinase, STE STE20 0.0162 0.0078 0.1709
Brugia malayi Protein kinase domain containing protein 0.023 0.0143 0.0509
Toxoplasma gondii AGC kinase 0.0251 0.0162 0.3662
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0431 0.0333 0.2386
Entamoeba histolytica hypothetical protein 0.0093 0.0012 0.0172
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Echinococcus multilocularis Glutaredoxin protein 5 0.0225 0.0137 0.0981
Loa Loa (eye worm) TK/FER protein kinase 0.0197 0.0111 0.0405
Onchocerca volvulus 0.0352 0.0257 0.2085
Echinococcus multilocularis protein kinase c iota type 0.054 0.0436 0.3128
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0176 0.0091 0.0863
Echinococcus granulosus contactin 0.0115 0.0034 0.0196
Loa Loa (eye worm) TK protein kinase 0.0093 0.0012 0.0037
Loa Loa (eye worm) hypothetical protein 0.0093 0.0012 0.0037
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Leishmania major protein kinase, putative 0.0161 0.0077 0.184
Echinococcus granulosus casein kinase I alpha 0.0206 0.0119 0.0704
Entamoeba histolytica protein kinase domain containing protein 0.019 0.0104 0.1777
Entamoeba histolytica serine/threonine protein kinase, putative 0.0499 0.0397 0.6858
Echinococcus granulosus c src tyrosine kinase 0.0271 0.0181 0.1073
Loa Loa (eye worm) hypothetical protein 0.0104 0.0023 0.0078
Loa Loa (eye worm) hypothetical protein 0.0226 0.0139 0.051
Schistosoma mansoni serine/threonine protein kinase 0.0343 0.0249 0.2482
Echinococcus multilocularis SHC transforming protein 3 0.0104 0.0023 0.016
Schistosoma mansoni serine/threonine-protein kinase 0.0309 0.0217 0.2153
Trypanosoma cruzi Protein kinase B 0.0309 0.0217 0.5415
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Trichomonas vaginalis CMGC family protein kinase 0.0224 0.0136 0.2966
Schistosoma mansoni serine/threonine-protein kinase 0.0309 0.0217 0.2153
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus granulosus tyrosine protein kinase shark 0.0584 0.0478 0.2836
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0093 0.0012 0.0172
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0171 0.0086 0.0614
Echinococcus multilocularis casein kinase I alpha 0.0206 0.0119 0.0852
Echinococcus multilocularis kinase suppressor of Ras 1 0.0093 0.0012 0.0082
Entamoeba histolytica protein kinase, putative 0.042 0.0322 0.5549
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0087 0.0007 0.0017
Echinococcus multilocularis hemicentin 1 0.0087 0.0007 0.0043
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0431 0.0333 0.1973
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.016 0.0076 0.1832
Echinococcus granulosus retinal guanylyl cyclase 2 0.0093 0.0012 0.0068
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.016 0.0076 0.1832
Trypanosoma cruzi p21-activated kinase 3, putative 0.0108 0.0026 0.0558
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0093 0.0013 0.0181
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.016 0.0076 0.1832
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Echinococcus multilocularis natriuretic peptide receptor 1 0.0093 0.0012 0.0082
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0499 0.0397 0.1477
Onchocerca volvulus 0.0206 0.0119 0.0965
Trichomonas vaginalis CAMK family protein kinase 0.0499 0.0397 0.883
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus multilocularis tyrosine kinase 0.0197 0.0111 0.079
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.0174 0.3816
Echinococcus multilocularis receptor type guanylyl cyclase 0.0096 0.0016 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0167 0.0083 0.1762
Brugia malayi Protein kinase domain containing protein 0.1023 0.0894 0.3319
Loa Loa (eye worm) protein kinase domain-containing protein 0.0093 0.0012 0.0037
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0297 0.0206 0.4532
Loa Loa (eye worm) AGC/AKT protein kinase 0.0554 0.0449 0.1672
Brugia malayi follicle stimulating hormone receptor 0.0237 0.0149 0.0532
Brugia malayi Protein kinase domain containing protein 0.035 0.0256 0.0935
Loa Loa (eye worm) TK/EPH protein kinase 0.0241 0.0152 0.0562
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0104 0.0023 0.0078
Schistosoma mansoni tyrosine kinase 0.0453 0.0353 0.3545
Loa Loa (eye worm) hypothetical protein 0.0115 0.0034 0.0118
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0076 0.1617
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0093 0.0012 0.0173
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0294 0.0203 0.1204
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0306 0.0214 0.0792
Plasmodium falciparum protein serine/threonine kinase-1 0.0343 0.0249 0.7716
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0271 0.0181 0.1299
Trichomonas vaginalis AGC family protein kinase 0.042 0.0322 0.7134
Leishmania major protein kinase, putative 0.0093 0.0012 0.0196
Trypanosoma brucei protein kinase, putative 0.0161 0.0077 0.1625
Schistosoma mansoni serine/threonine protein kinase 0.0458 0.0359 0.3601
Loa Loa (eye worm) hypothetical protein 0.0083 0.0003 0.0004
Brugia malayi Protein kinase domain containing protein 0.0264 0.0174 0.0627
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0093 0.0012 0.0082
Trichomonas vaginalis CAMK family protein kinase 0.0499 0.0397 0.883
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Onchocerca volvulus 0.0197 0.0111 0.0896
Echinococcus multilocularis dual specificity 0.0261 0.0171 0.1227
Loa Loa (eye worm) hypothetical protein 0.0093 0.0012 0.0037
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0115 0.0034 0.0196
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0093 0.0012 0.002
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0401 0.0304 0.218
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.001 0.0056
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0251 0.0162 0.1157
Entamoeba histolytica protein kinase , putative 0.042 0.0322 0.5549
Schistosoma mansoni serine/threonine protein kinase 0.0401 0.0304 0.3041
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.018 0.0095 0.0677
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus multilocularis cyclin dependent kinase 0.0264 0.0174 0.1247
Loa Loa (eye worm) protein kinase domain-containing protein 0.0396 0.0299 0.111
Brugia malayi Immunoglobulin I-set domain containing protein 0.0094 0.0013 0.0024
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0115 0.0034 0.0237
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0306 0.0215 0.0794
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0093 0.0012 0.0055
Loa Loa (eye worm) TK protein kinase 0.0093 0.0012 0.0037
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0206 0.0119 0.0438
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0104 0.0023 0.0078
Schistosoma mansoni tyrosine kinase 0.0824 0.0705 0.7139
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0115 0.0034 0.0237
Brugia malayi hypothetical protein 0.0119 0.0037 0.0115
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0162 0.1586
Schistosoma mansoni hypothetical protein 0.0098 0.0017 0.0107
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0086 0.0812
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus granulosus insulin receptor 0.0824 0.0705 0.4182
Brugia malayi Protein kinase domain containing protein 0.0306 0.0215 0.0778
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0093 0.0012 0.0172
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0221 0.0134 0.0476
Entamoeba histolytica protein kinase domain containing protein 0.0408 0.0311 0.5354
Echinococcus granulosus casein kinase i 0.0206 0.0119 0.0704
Trichomonas vaginalis TKL family protein kinase 0.0095 0.0014 0.0218
Entamoeba histolytica receptor protein kinase, putative 0.0093 0.0012 0.0172
Entamoeba histolytica hypothetical protein 0.0093 0.0013 0.0181
Schistosoma mansoni tensin 0.0104 0.0023 0.0166
Trypanosoma cruzi casein kinase, putative 0.0206 0.0119 0.2923
Echinococcus granulosus rho-associated protein kinase 1 0.0981 0.0853 0.5066
Brugia malayi p70 ribosomal S6 kinase beta 0.0538 0.0434 0.16
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0206 0.0119 0.0438
Plasmodium falciparum glycogen synthase kinase 3 0.0408 0.0311 0.9647
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0076 0.0713
Schistosoma mansoni tensin-related 0.0104 0.0023 0.0166
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0093 0.0012 0.0037
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0408 0.0311 0.3109
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0431 0.0333 0.2386
Brugia malayi Protein kinase domain containing protein 0.0216 0.0129 0.0457
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0184 0.0098 0.0359
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0143 0.139
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0093 0.0012 0.0172
Loa Loa (eye worm) hypothetical protein 0.0087 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.016 0.0076 0.0276
Schistosoma mansoni serine/threonine protein kinase 0.0499 0.0397 0.3996
Entamoeba histolytica protein kinase, putative 0.0092 0.0011 0.0155
Giardia lamblia Kinase, CMGC MAPK 0.016 0.0076 0.1668
Trypanosoma cruzi cdc2-related kinase 1 0.0264 0.0174 0.4322
Brugia malayi Tyrosine-protein kinase PR2 0.0093 0.0012 0.002
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0906 0.0783 0.5622
Schistosoma mansoni protein kinase 0.0093 0.0012 0.0055
Plasmodium vivax tyrosine kinase-like protein, putative 0.0093 0.0012 0.0243
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0095 0.0014 0.0218
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0171 0.0086 0.208
Entamoeba histolytica protein kinase, putative 0.0194 0.0108 0.1836
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0159 0.0075 0.1804
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Entamoeba histolytica protein kinase domain containing protein 0.0408 0.0311 0.5354
Echinococcus granulosus tyrosine protein kinase csk 0.0093 0.0012 0.0068
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0104 0.0023 0.0166
Entamoeba histolytica protein kinase, putative 0.0137 0.0054 0.0903
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0172 0.0087 0.1482
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0724 0.0611 0.3624
Echinococcus multilocularis Immunoglobulin 0.0176 0.0091 0.065
Schistosoma mansoni protein tyrosine kinase 0.0093 0.0012 0.0055
Echinococcus granulosus neuroglian 0.0222 0.0134 0.0794
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Schistosoma mansoni ste20-related kinase 0.0381 0.0285 0.2849
Schistosoma mansoni cell adhesion molecule 0.0115 0.0034 0.0276
Brugia malayi Serine/threonine-protein kinase SULU 0.0412 0.0315 0.1153
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0346 0.0252 0.0934
Trichomonas vaginalis STE family protein kinase 0.0206 0.0119 0.2578
Brugia malayi Temporarily assigned gene name protein 59 0.0226 0.0139 0.0494
Leishmania major protein kinase A catalytic subunit isoform 2 0.0251 0.0162 0.4004
Echinococcus multilocularis protein kinase c epsilon type 0.0392 0.0295 0.2118
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0104 0.2251
Echinococcus multilocularis Niemann Pick C1 protein 0.0142 0.0059 0.0418
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0104 0.2251
Onchocerca volvulus 0.0981 0.0853 0.6911
Echinococcus granulosus lachesin 0.0087 0.0007 0.0036
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.023 0.0143 0.3518
Loa Loa (eye worm) hypothetical protein 0.0093 0.0012 0.0037
Entamoeba histolytica protein kinase, putative 0.0159 0.0075 0.1269
Brugia malayi Protein kinase domain containing protein 0.1098 0.0965 0.3586
Brugia malayi STAT protein, DNA binding domain containing protein 0.0104 0.0023 0.0061
Onchocerca volvulus 0.0137 0.0055 0.0442
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0171 0.0086 0.0314
Loa Loa (eye worm) AUR protein kinase 0.042 0.0322 0.1195
Brugia malayi SH2 domain containing protein 0.0104 0.0023 0.0061
Loa Loa (eye worm) hypothetical protein 0.0104 0.0023 0.0078
Loa Loa (eye worm) TK/FER protein kinase 0.0093 0.0012 0.0037
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0226 0.0139 0.3018
Echinococcus multilocularis growth factor receptor bound protein 2 0.0179 0.0094 0.0668
Echinococcus granulosus tyrosine protein kinase Src42A 0.0431 0.0333 0.1973
Schistosoma mansoni protein kinase 0.0096 0.0016 0.0092
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0076 0.1617
Brugia malayi Protein kinase domain containing protein 0.0554 0.0449 0.1657
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0226 0.0139 0.135
Echinococcus granulosus tyrosine protein kinase Fyn 0.0431 0.0333 0.1973
Echinococcus granulosus Immunoglobulin 0.0176 0.0091 0.0537
Echinococcus granulosus tyrosine protein kinase pr2 0.0093 0.0012 0.0068
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0104 0.0023 0.016
Trichomonas vaginalis AGC family protein kinase 0.0093 0.0012 0.0173
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Loa Loa (eye worm) hypothetical protein 0.0103 0.0021 0.0072
Brugia malayi Protein kinase domain containing protein 0.0197 0.0111 0.0389
Trichomonas vaginalis CMGC family protein kinase 0.0408 0.0311 0.6882
Toxoplasma gondii CMGC kinase, CK2 family 0.019 0.0104 0.2331
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0161 0.0077 0.184
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Onchocerca volvulus 0.0104 0.0023 0.0185
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0086 0.0812
Trypanosoma brucei cdc2-related kinase 1 0.0264 0.0174 0.3816
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Echinococcus multilocularis casein kinase I delta 0.0206 0.0119 0.0852
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0093 0.0012 0.0173
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0533 0.0429 0.2546
Trichomonas vaginalis AGC family protein kinase 0.035 0.0256 0.5664
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0271 0.0181 0.1787
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0297 0.0206 0.5133
Entamoeba histolytica tyrosin kinase, putative 0.0093 0.0012 0.0172
Echinococcus multilocularis signal transduction protein lnk realted 0.0104 0.0023 0.016
Echinococcus multilocularis calcium activated potassium channel 0.0258 0.0169 0.1208
Brugia malayi Doublecortin family protein 0.0282 0.0192 0.0693
Entamoeba histolytica casein kinase, putative 0.0206 0.0119 0.2032
Echinococcus granulosus casein kinase I gamma 0.0396 0.0299 0.1774
Brugia malayi Immunoglobulin I-set domain containing protein 0.0115 0.0034 0.0101
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0191 0.0106 0.0755
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Echinococcus granulosus fch and double sh3 domains protein 2 0.0082 0.0002 0.0009
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0159 0.0075 0.1804
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0313 0.0221 0.1585
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0206 0.0119 0.0704
Loa Loa (eye worm) hypothetical protein 0.0328 0.0235 0.0871
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0104 0.0023 0.016
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0162 0.0078 0.1872
Plasmodium falciparum cGMP-dependent protein kinase 0.0253 0.0164 0.5024
Schistosoma mansoni hypothetical protein 0.0185 0.01 0.0951
Echinococcus granulosus casein kinase ii subunit alpha 0.019 0.0104 0.0617
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Entamoeba histolytica serine/threonine protein kinase, putative 0.01 0.0019 0.0302
Loa Loa (eye worm) hypothetical protein 0.0087 0.0007 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0554 0.0449 1
Brugia malayi Pleckstrin Homology Domain 0.0092 0.0012 0.0019
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0191 0.0106 0.0387
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus granulosus protein kinase c iota type 0.054 0.0436 0.2586
Brugia malayi Protein kinase domain containing protein 0.0121 0.0039 0.012
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0261 0.0171 0.0617
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0431 0.0333 0.2386
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0261 0.0171 0.3888
Echinococcus granulosus tyrosine kinase 0.0356 0.0262 0.1553
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0906 0.0783 0.4648
Loa Loa (eye worm) TK/FAK protein kinase 0.1023 0.0894 0.3331
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.0221 0.2195
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0093 0.0012 0.0055
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0032 0.0262
Entamoeba histolytica protein kinase, putative 0.0182 0.0097 0.1649
Entamoeba histolytica tyrosin kinase, putative 0.0093 0.0012 0.0172
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Echinococcus multilocularis tyrosine protein kinase otk 0.0087 0.0007 0.0043
Schistosoma mansoni cell adhesion molecule 0.0246 0.0157 0.1538
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0346 0.0252 0.0918
Brugia malayi Protein kinase domain containing protein 0.0343 0.0249 0.0908
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0206 0.0119 0.0851
Echinococcus granulosus suppressor of cytokine signaling 7 0.0104 0.0023 0.0132
Echinococcus multilocularis protein kinase shaggy 0.0408 0.0311 0.2228
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Giardia lamblia Kinase, NEK 0.0256 0.0167 0.4009
Giardia lamblia Kinase, CAMK CAMKL 0.0171 0.0086 0.1921
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0251 0.0162 0.4004
Schistosoma mansoni ephrin receptor 0.0209 0.0122 0.1182
Brugia malayi SRC-1 0.0431 0.0333 0.122
Loa Loa (eye worm) hypothetical protein 0.0237 0.0149 0.0547
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.016 0.0076 0.1675
Echinococcus granulosus growth factor receptor bound protein 2 0.0182 0.0097 0.0573
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0431 0.0333 0.2386
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0573 0.0468 0.3355
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0251 0.0162 0.3662
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0402 0.0306 0.1134
Echinococcus granulosus protein kinase 0.0342 0.0248 0.1471
Schistosoma mansoni serine/threonine protein kinase 0.0346 0.0252 0.2509
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0082 0.0002 0.001
Entamoeba histolytica protein kinase, putative 0.0554 0.0449 0.7762
Brugia malayi Protein kinase domain containing protein 0.1098 0.0965 0.3586
Schistosoma mansoni tensin-related 0.0104 0.0023 0.0166
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0408 0.0311 0.7794
Entamoeba histolytica hypothetical protein, conserved 0.0093 0.0012 0.0172
Brugia malayi Immunoglobulin I-set domain containing protein 0.0204 0.0118 0.0417
Echinococcus granulosus epidermal growth factor receptor 0.1119 0.0984 0.5845
Schistosoma mansoni serine/threonine protein kinase 0.0875 0.0753 0.7634
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0093 0.0012 0.0173
Schistosoma mansoni growth factor receptor-bound protein 0.0182 0.0097 0.0925
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0216 0.0129 0.0473
Brugia malayi Fes/CIP4 homology domain containing protein 0.0212 0.0126 0.0445
Schistosoma mansoni tyrosine kinase 0.0093 0.0012 0.0055
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.001 0.003
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0401 0.0304 0.218
Trypanosoma cruzi casein kinase, putative 0.0206 0.0119 0.2923
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0294 0.0203 0.1456
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0093 0.0012 0.0172
Schistosoma mansoni hypothetical protein 0.0093 0.0012 0.0055
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0431 0.0333 0.2386
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0343 0.0249 0.6234
Schistosoma mansoni tyrosine kinase 0.0469 0.0369 0.3706
Trypanosoma cruzi NIMA-related kinase, putative 0.01 0.0019 0.0386
Giardia lamblia Kinase, CMGC GSK 0.0408 0.0311 0.775
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.01 0.0019 0.0478
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0293 0.0202 0.6218
Schistosoma mansoni tyrosine kinase 0.0093 0.0012 0.0055
Schistosoma mansoni tyrosine kinase 0.0741 0.0626 0.6336
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0342 0.0248 0.092
Brugia malayi Protein kinase domain containing protein 0.0824 0.0705 0.2613
Brugia malayi Protein kinase domain containing protein 0.0402 0.0306 0.1119
Echinococcus granulosus neuroglian 0.0115 0.0034 0.0196
Trypanosoma brucei Casein kinase II 0.019 0.0104 0.2251
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.042 0.0322 0.5549
Schistosoma mansoni serine/threonine protein kinase 0.0401 0.0304 0.3041
Schistosoma mansoni protein kinase 0.0206 0.0119 0.1151
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0251 0.0162 0.0957
Echinococcus granulosus serine:threonine protein kinase N2 0.0549 0.0444 0.2636
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Plasmodium falciparum NIMA related kinase 4 0.01 0.0019 0.0478
Echinococcus granulosus NDR protein kinase 0.0313 0.0221 0.131
Trypanosoma brucei rac serine-threonine kinase, putative 0.0554 0.0449 1
Echinococcus multilocularis rho associated protein kinase 0.0981 0.0853 0.6128
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1555 0.1397 0.5213
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0034 0.0121
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0172 0.0087 0.0302
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0698 0.0585 0.4202
Schistosoma mansoni tyrosine kinase 0.0648 0.0538 0.5439
Echinococcus multilocularis neuroglian 0.0115 0.0034 0.0237
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0264 0.0174 0.4322
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0171 0.0086 0.208
Trichomonas vaginalis CAMK family protein kinase 0.0238 0.015 0.3266
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Giardia lamblia Kinase, CMGC CK2 0.019 0.0104 0.24
Trichomonas vaginalis STE family protein kinase 0.01 0.0019 0.0341
Entamoeba histolytica SH2 domain containing protein 0.0104 0.0023 0.0361
Loa Loa (eye worm) TK/DDR protein kinase 0.0093 0.0012 0.0037
Echinococcus granulosus casein kinase I delta 0.0206 0.0119 0.0704
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.001 0.0068
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0156 0.0072 0.0263
Loa Loa (eye worm) TK/FER protein kinase 0.0093 0.0012 0.0037
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0392 0.0295 0.1096
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0499 0.0397 0.2357
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0093 0.0012 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.0174 0.1714
Onchocerca volvulus Serine\/threonine kinase homolog 0.0499 0.0397 0.3218
Loa Loa (eye worm) hypothetical protein 0.0093 0.0012 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Plasmodium falciparum tyrosine kinase-like protein 0.0093 0.0012 0.0243
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0164 0.1608
Schistosoma mansoni serine/threonine protein kinase 0.0472 0.0371 0.3727
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.01 0.0019 0.0386
Schistosoma mansoni signal transduction protein lnk-related 0.0104 0.0023 0.0166
Echinococcus granulosus neural Wiskott Aldrich syndrome protein 0.0098 0.0017 0.0098
Schistosoma mansoni tyrosine protein kinase 0.0093 0.0012 0.0055
Echinococcus multilocularis casein kinase i 0.0206 0.0119 0.0852
Echinococcus multilocularis integrin linked protein kinase 0.0093 0.0012 0.0082
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.001 0.0056
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0104 0.2251
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0431 0.0333 0.2386
Schistosoma mansoni serine/threonine protein kinase 0.0137 0.0054 0.0486
Brugia malayi Immunoglobulin I-set domain containing protein 0.1555 0.1397 0.5205
Trichomonas vaginalis TK family protein kinase 0.0095 0.0014 0.0218
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0373 0.0278 0.103
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Entamoeba histolytica p21-activated kinase 0.0222 0.0134 0.2297
Echinococcus granulosus tyrosine kinase 0.0096 0.0016 0.0089
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0431 0.0333 0.2386
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0086 0.0812
Brugia malayi RhoGAP domain containing protein 0.018 0.0095 0.033
Schistosoma mansoni protein kinase 0.0161 0.0077 0.0716
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.016 0.0076 0.1832
Schistosoma mansoni hypothetical protein 0.0098 0.0017 0.0107
Schistosoma mansoni tyrosine kinase 0.0093 0.0012 0.0055
Loa Loa (eye worm) hypothetical protein 0.0204 0.0118 0.0433
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Brugia malayi Serine/threonine-protein kinase Pim-3 0.1066 0.0935 0.3473
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Entamoeba histolytica protein kinase, putative 0.0159 0.0075 0.1269
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0408 0.0311 0.1153
Entamoeba histolytica casein kinase, putative 0.019 0.0104 0.1777
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Echinococcus granulosus hypothetical protein 0.0104 0.0023 0.0132
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.042 0.0322 0.2308
Schistosoma mansoni wiskott-aldrich syndrome protein 0.0098 0.0017 0.0107
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0093 0.0012 0.0055
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.019 0.0104 0.3155
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0093 0.0012 0.002
Schistosoma mansoni serine/threonine kinase 0.0313 0.0221 0.2195
Brugia malayi Protein kinase domain containing protein 0.0197 0.0111 0.0389
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0313 0.0221 0.131
Echinococcus granulosus titin 0.0142 0.0059 0.0348
Trypanosoma brucei polo-like protein kinase 0.0499 0.0397 0.883
Schistosoma mansoni serine/threonine protein kinase 0.0464 0.0364 0.3651
Loa Loa (eye worm) hypothetical protein 0.0087 0.0007 0.0017
Entamoeba histolytica protein kinase domain containing protein 0.0098 0.0017 0.0267
Echinococcus multilocularis epidermal growth factor receptor 0.0741 0.0626 0.4495
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0162 0.1586
Brugia malayi protein unc-22 0.0142 0.0059 0.0197
Schistosoma mansoni tyrosine kinase 0.0096 0.0016 0.0092
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0251 0.0162 0.4004
Echinococcus granulosus defective proboscis extension response 0.0176 0.0091 0.0537
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0852 0.0732 0.4343
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0093 0.0012 0.0082
Echinococcus multilocularis PAK box P21 Rho binding 0.0166 0.0082 0.0583
Trichomonas vaginalis AGC family protein kinase 0.0156 0.0072 0.153
Trichomonas vaginalis CAMK family protein kinase 0.0499 0.0397 0.883
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0256 0.0167 0.3774
Trypanosoma cruzi casein kinase, putative 0.0206 0.0119 0.2923
Echinococcus multilocularis dual specificity protein kinase clk2 0.0343 0.0249 0.1787
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0256 0.0167 0.5108
Brugia malayi Stress-activated protein kinase jnk-1 0.0488 0.0387 0.1424
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0164 0.1608
Loa Loa (eye worm) TK protein kinase 0.0093 0.0012 0.0037
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0012 0.0055
Loa Loa (eye worm) AGC/PKA protein kinase 0.0251 0.0162 0.0596
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.0176 0.1728
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Loa Loa (eye worm) hypothetical protein 0.0172 0.0087 0.0318
Brugia malayi Kinase associated domain 1 family protein 0.0185 0.01 0.0348
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0253 0.0164 0.3712
Echinococcus granulosus casein kinase I alpha 0.0206 0.0119 0.0704
Schistosoma mansoni vav2 0.0196 0.011 0.106
Schistosoma mansoni SH2A 0.0104 0.0023 0.0166
Echinococcus granulosus raf serine:threonine protein kinase 0.0169 0.0084 0.0495
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0093 0.0012 0.0172
Entamoeba histolytica hypothetical protein 0.0093 0.0012 0.0172
Brugia malayi Protein kinase domain containing protein 0.0197 0.0111 0.0389
Plasmodium falciparum protein kinase, putative 0.0093 0.0012 0.0243
Echinococcus multilocularis dual specificity 0.0261 0.0171 0.1227
Echinococcus multilocularis tyrosine protein kinase 0.0528 0.0425 0.3047
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Schistosoma mansoni protein kinase 0.0093 0.0012 0.0055
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0271 0.0181 0.1074
Loa Loa (eye worm) casein kinase 0.0327 0.0235 0.0869
Schistosoma mansoni serine/threonine protein kinase 0.0412 0.0315 0.315
Entamoeba histolytica serine/threonine protein kinase, putative 0.0171 0.0086 0.1457
Schistosoma mansoni GTPase activating protein 0.0104 0.0023 0.0166
Brugia malayi Protein kinase domain containing protein 0.2907 0.2679 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0084 0.0004 0.0039
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0093 0.0012 0.0055
Giardia lamblia Kinase, CMGC CDK 0.0264 0.0174 0.4208
Giardia lamblia Kinase, NEK 0.0256 0.0167 0.4009
Echinococcus granulosus tyrosine protein kinase HCK 0.0252 0.0163 0.0967
Entamoeba histolytica protein kinase, putative 0.0156 0.0072 0.122
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0093 0.0012 0.0173
Toxoplasma gondii AGC kinase 0.0538 0.0434 1
Loa Loa (eye worm) hypothetical protein 0.0378 0.0283 0.1048
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0136 0.1326
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0142 0.0059 0.0213
Echinococcus granulosus casein kinase I delta 0.0206 0.0119 0.0704
Brugia malayi hypothetical protein 0.0204 0.0118 0.0417
Plasmodium vivax protein kinase, putative 0.012 0.0038 0.106
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0093 0.0012 0.0179
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0724 0.0611 0.4383
Echinococcus granulosus c-Jun N-terminal kinases 0.0488 0.0387 0.2295
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Schistosoma mansoni protein kinase 0.0568 0.0463 0.4664
Trypanosoma brucei protein kinase, putative 0.0408 0.0311 0.6882
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0225 0.0137 0.0811
Echinococcus granulosus Niemann Pick C1 protein 0.0142 0.0059 0.0346
Schistosoma mansoni serine/threonine protein kinase 0.0464 0.0364 0.3651
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0197 0.0111 0.1883
Brugia malayi Immunoglobulin I-set domain containing protein 0.0098 0.0017 0.0038
Onchocerca volvulus 0.0142 0.0059 0.0479
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0137 0.0054 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.042 0.0322 0.3224
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0093 0.0012 0.0068
Schistosoma mansoni neuroglian 0.0115 0.0034 0.0276
Loa Loa (eye worm) TK/FER protein kinase 0.0197 0.0111 0.0405
Loa Loa (eye worm) hypothetical protein 0.0104 0.0023 0.0078
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0453 0.0353 0.2534
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0104 0.0023 0.0132
Schistosoma mansoni protein kinase 0.0342 0.0248 0.2471
Loa Loa (eye worm) TK/ACK protein kinase 0.0093 0.0012 0.0037
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Echinococcus multilocularis casein kinase I gamma 0.0396 0.0299 0.2145
Schistosoma mansoni atypical protein kinase C 0.0551 0.0446 0.4497
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0162 0.0078 0.1315
Echinococcus multilocularis aurora kinase A 0.042 0.0322 0.2308
Loa Loa (eye worm) hypothetical protein 0.0275 0.0185 0.0682
Toxoplasma gondii NEK kinase 0.01 0.0019 0.0353
Brugia malayi casein kinase 1, delta 0.0206 0.0119 0.0421
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0346 0.0252 0.1493
Echinococcus granulosus protein kinase shaggy 0.0408 0.0311 0.1842
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0191 0.0106 0.3194
Echinococcus granulosus epidermal growth factor receptor 0.0741 0.0626 0.3716
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0343 0.0249 0.6234
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Giardia lamblia Kinase, NEK 0.01 0.0019 0.0194
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0741 0.0626 0.3716
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0093 0.0012 0.0082
Echinococcus multilocularis myotubularin protein 13 0.0092 0.0012 0.0079
Brugia malayi Protein kinase domain containing protein 0.1066 0.0935 0.3473
Echinococcus multilocularis N chimaerin 0.018 0.0095 0.0677
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Echinococcus granulosus netrin receptor unc 5 0.0094 0.0013 0.0074
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0104 0.2251
Onchocerca volvulus 0.0104 0.0023 0.0185
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0226 0.0139 0.3418
Trypanosoma cruzi aurora B kinase, putative 0.042 0.0322 0.8079
Brugia malayi Sex muscle abnormal protein 5 0.0179 0.0094 0.0326
Brugia malayi SH2 domain containing protein 0.0104 0.0023 0.0061
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0261 0.0171 0.4251
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0093 0.0012 0.0172
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0091 0.001 0.007
Echinococcus multilocularis tyrosine protein kinase Blk 0.0356 0.0262 0.1878
Echinococcus granulosus kinase suppressor of Ras 1 0.0093 0.0012 0.0068
Brugia malayi P21-Rho-binding domain containing protein 0.0098 0.0017 0.0039
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0093 0.0012 0.002
Schistosoma mansoni tyrosine kinase 0.0093 0.0012 0.0055
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0431 0.0333 0.1973
Brugia malayi Protein kinase domain containing protein 0.0313 0.0221 0.0803
Trichomonas vaginalis CAMK family protein kinase 0.0499 0.0397 0.883
Loa Loa (eye worm) hypothetical protein 0.0087 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0104 0.0023 0.0078
Plasmodium vivax protein kinase Crk2 0.0264 0.0174 0.5349
Onchocerca volvulus 0.0335 0.0242 0.1961
Loa Loa (eye worm) TK/FER protein kinase 0.0197 0.0111 0.0405
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0191 0.0106 0.236
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0093 0.0012 0.0172
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.1066 0.0935 0.7569
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0412 0.0315 0.1865
Schistosoma mansoni ephrin receptor 0.0121 0.0039 0.0331
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0108 0.0026 0.0493
Echinococcus granulosus hypothetical protein 0.0275 0.0185 0.1094
Giardia lamblia Kinase, CK1 Casein kinase 0.0206 0.0119 0.2782
Plasmodium falciparum calcium-dependent protein kinase 1 0.0191 0.0106 0.3194
Entamoeba histolytica tyrosin kinase, putative 0.0098 0.0017 0.0267
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0018 0.0284
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0408 0.0311 0.2228
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0225 0.0137 0.0981
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0404 0.0307 0.1123
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0162 0.0078 0.1653
Entamoeba histolytica protein kinase, putative 0.0084 0.0004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0261 0.0171 0.0633
Loa Loa (eye worm) hypothetical protein 0.0226 0.0139 0.051
Echinococcus granulosus CDC7 cell division cycle 7 0.0224 0.0136 0.0806
Brugia malayi serine/threonine-protein kinase plk-2 0.0499 0.0397 0.1462
Echinococcus granulosus cGMP dependent protein kinase 1 0.0253 0.0164 0.097
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0093 0.0012 0.0068
Loa Loa (eye worm) hypothetical protein 0.0204 0.0118 0.0433
Leishmania major casein kinase II, putative 0.019 0.0104 0.2549
Entamoeba histolytica receptor protein kinase, putative 0.0093 0.0012 0.0172
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Loa Loa (eye worm) hypothetical protein 0.0104 0.0023 0.0078
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0206 0.0119 0.0704
Entamoeba histolytica protein kinase, putative 0.0252 0.0163 0.2799
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0171 0.3753
Plasmodium falciparum NIMA related kinase 1 0.0256 0.0167 0.5108
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Schistosoma mansoni rap gtpase-activating protein 0.0226 0.0139 0.135
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Onchocerca volvulus Huntingtin homolog 0.0119 0.0037 0.0302
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0162 0.0078 0.1315
Plasmodium falciparum calcium-dependent protein kinase 2 0.0191 0.0106 0.3194
Echinococcus multilocularis SH2 motif 0.0104 0.0023 0.016
Onchocerca volvulus 0.0104 0.0023 0.0185
Plasmodium vivax tyrosine kinase-like protein, putative 0.0093 0.0012 0.0243
Toxoplasma gondii histone kinase SNF1, putative 0.0171 0.0086 0.1902
Trichomonas vaginalis CAMK family protein kinase 0.0238 0.015 0.3266
Echinococcus granulosus protein kinase 0.0093 0.0012 0.0068
Echinococcus granulosus protein kinase C gamma type 0.0388 0.0292 0.1729
Brugia malayi Peroxidasin 0.0087 0.0007 0.0002
Echinococcus granulosus peroxidasin 0.0087 0.0007 0.0039
Echinococcus granulosus roundabout 2 0.0115 0.0034 0.0196
Schistosoma mansoni cell adhesion molecule 0.0115 0.0034 0.0276
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0401 0.0304 0.1802
Trichomonas vaginalis protein tyrosine kinase, putative 0.0093 0.0012 0.0173
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0012 0.0173
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0171 0.3753
Plasmodium vivax serine/threonine kinase-1, putative 0.0343 0.0249 0.7716
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0313 0.0221 0.131
Schistosoma mansoni tyrosine kinase 0.048 0.0379 0.3813
Schistosoma mansoni serine/threonine protein kinase 0.1066 0.0935 0.949
Echinococcus granulosus activated cdc42 kinase 1 0.0093 0.0012 0.0068
Schistosoma mansoni tyrosine kinase 0.0093 0.0012 0.0055
Entamoeba histolytica protein kinase, putative 0.0554 0.0449 0.7762
Plasmodium falciparum protein kinase 5 0.0264 0.0174 0.5349
Entamoeba histolytica hypothetical protein 0.0093 0.0012 0.0172
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Loa Loa (eye worm) hypothetical protein 0.0216 0.0129 0.0474
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0282 0.0192 0.0709
Echinococcus multilocularis dual specificity 0.023 0.0143 0.102
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0087 0.0007 0.0043
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0293 0.0202 0.1445
Plasmodium falciparum calcium-dependent protein kinase 3 0.0191 0.0106 0.3194
Loa Loa (eye worm) TK protein kinase 0.0356 0.0262 0.0971
Loa Loa (eye worm) SH2 domain-containing protein 0.0104 0.0023 0.0078
Entamoeba histolytica protein kinase, putative 0.0538 0.0434 0.7495
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0104 0.0023 0.016
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0143 0.0059 0.0214
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0104 0.0023 0.016
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0156 0.0072 0.0263
Echinococcus multilocularis cyclin dependent kinase 1 0.0264 0.0174 0.1247
Echinococcus multilocularis Immunoglobulin 0.0176 0.0091 0.065
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Trypanosoma brucei aurora B kinase 0.042 0.0322 0.7134
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Entamoeba histolytica protein kinase, putative 0.0137 0.0054 0.0903
Loa Loa (eye worm) AGC/NDR protein kinase 0.0313 0.0221 0.0819
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0264 0.0174 0.1031
Echinococcus multilocularis twitchin 0.0114 0.0032 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.0054 0.1126
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0297 0.0206 0.5133
Echinococcus granulosus cyclin dependent kinase 1 0.0264 0.0174 0.1031
Echinococcus granulosus cyclin dependent kinase 0.0264 0.0174 0.1031
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0191 0.0106 0.0755
Echinococcus multilocularis roundabout 2 0.0115 0.0034 0.0237
Brugia malayi integrin-linked kinase 0.0093 0.0012 0.002
Brugia malayi SH2 domain containing protein 0.0104 0.0023 0.0061
Loa Loa (eye worm) TK/FER protein kinase 0.0197 0.0111 0.0405
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0226 0.0139 0.3418
Plasmodium falciparum NIMA related kinase 2 0.01 0.0019 0.0478
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0796 0.0679 0.4875
Entamoeba histolytica protein kinase 2, putative 0.0293 0.0202 0.3465
Loa Loa (eye worm) hypothetical protein 0.0103 0.0021 0.0072
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0093 0.0012 0.0082
Onchocerca volvulus Tyrosine kinase homolog 0.1383 0.1235 1
Loa Loa (eye worm) hypothetical protein 0.0838 0.0718 0.2677
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0408 0.0311 0.1153
Echinococcus granulosus tyrosine protein kinase csk 0.0093 0.0012 0.0068
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Brugia malayi SH2 domain containing protein 0.0104 0.0023 0.0061
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Schistosoma mansoni serine/threonine protein kinase 0.0392 0.0295 0.2953
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Brugia malayi serine/threonine kinase 12 0.042 0.0322 0.118
Schistosoma mansoni tyrosine kinase 0.1012 0.0883 0.8963
Mycobacterium ulcerans transcriptional regulator 1.0633 1 1
Schistosoma mansoni tyrosine kinase 0.0431 0.0333 0.3335
Brugia malayi Variant SH3 domain containing protein 0.0179 0.0094 0.0326
Loa Loa (eye worm) CAMK protein kinase 0.0142 0.0059 0.0213
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0811 0.0693 0.4975
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0253 0.0164 0.1173
Loa Loa (eye worm) RGC/RGC protein kinase 0.0093 0.0012 0.0037
Echinococcus granulosus roundabout 2 0.0291 0.02 0.1186
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0076 0.1617
Loa Loa (eye worm) hypothetical protein 0.0104 0.0023 0.0078
Echinococcus granulosus cyclin dependent kinase 5 0.0264 0.0174 0.1031
Echinococcus multilocularis casein kinase ii subunit alpha 0.019 0.0104 0.0746
Loa Loa (eye worm) hypothetical protein 0.0099 0.0018 0.0061
Schistosoma mansoni protein kinase 0.0093 0.0012 0.0055
Entamoeba histolytica protein kinase, putative 0.0191 0.0106 0.1799
Loa Loa (eye worm) hypothetical protein 0.037 0.0275 0.102
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0343 0.0249 0.6234
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0431 0.0333 0.2386
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0297 0.0206 0.5133
Brugia malayi hypothetical protein 0.0226 0.0139 0.0494
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0093 0.0012 0.0037
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0108 0.0026 0.0073
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0093 0.0012 0.0055
Loa Loa (eye worm) RhoGAP domain-containing protein 0.018 0.0095 0.0347
Schistosoma mansoni protein kinase 0.0796 0.0679 0.6876
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0499 0.0397 0.2851
Echinococcus multilocularis transfer RNA-Thr 0.0093 0.0012 0.0082
Trichomonas vaginalis STE family protein kinase 0.0206 0.0119 0.2578
Schistosoma mansoni titin 0.0142 0.0059 0.0537
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0251 0.0162 0.1157
Echinococcus granulosus dual specificity 0.0261 0.0171 0.1014
Trichomonas vaginalis STE family protein kinase 0.0166 0.0082 0.1739
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0226 0.0139 0.082
Trichomonas vaginalis STE family protein kinase 0.0206 0.0119 0.2578
Echinococcus multilocularis expressed conserved protein 0.0093 0.0013 0.0087
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0458 0.0359 0.2127
Loa Loa (eye worm) TK/INSR protein kinase 0.0824 0.0705 0.2625
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0191 0.0106 0.236
Loa Loa (eye worm) hypothetical protein 0.0335 0.0242 0.0897
Echinococcus granulosus dual specificity 0.0261 0.0171 0.1014
Echinococcus multilocularis serine threonine protein kinase 0.0388 0.0292 0.2091
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0104 0.2251
Loa Loa (eye worm) TK/ABL protein kinase 0.0573 0.0468 0.1739
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0359 0.0264 0.0979
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0101 0.002 0.0136
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0251 0.0162 0.3536
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1857 0.1684 1
Echinococcus multilocularis protein kinase 0.0093 0.0012 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0156 0.0072 0.153
Echinococcus multilocularis FL cytokine receptor 0.0093 0.0012 0.0082
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0191 0.0106 0.3194
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0171 0.0086 0.1837
Loa Loa (eye worm) hypothetical protein 0.0252 0.0163 0.0602
Toxoplasma gondii aurora kinase 0.042 0.0322 0.7389
Leishmania major protein kinase A catalytic subunit isoform 1 0.0251 0.0162 0.4004
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0137 0.0054 0.0318
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0093 0.0012 0.0055
Trichomonas vaginalis CK1 family protein kinase 0.0206 0.0119 0.2581
Echinococcus granulosus Vam6:Vps39 protein 0.0226 0.0139 0.082
Echinococcus multilocularis tyrosine protein kinase csk 0.0093 0.0012 0.0082
Trichomonas vaginalis CAMK family protein kinase 0.0402 0.0306 0.6769
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0171 0.3753
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0104 0.0023 0.016
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0182 0.0097 0.0573
Echinococcus granulosus 3'partial|serine:threonine protein kinase PAK 2 0.0098 0.0017 0.0098
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Schistosoma mansoni tyrosine kinase 0.0093 0.0012 0.0055
Echinococcus multilocularis expressed protein 0.0159 0.0075 0.0536
Echinococcus multilocularis serotonin receptor 0.016 0.0076 0.0541
Echinococcus granulosus ephrin type A receptor 4 A 0.0209 0.0122 0.0722
Brugia malayi protein-tyrosine kinase 0.0356 0.0262 0.0956
Schistosoma mansoni tyrosine kinase 0.0093 0.0012 0.0055
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0104 0.0023 0.016
Onchocerca volvulus 0.0082 0.0002 0.0017
Brugia malayi Protein kinase domain containing protein 0.0159 0.0075 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0012 0.0173
Echinococcus multilocularis 0.0315 0.0223 0.1599
Loa Loa (eye worm) TK/FER protein kinase 0.0093 0.0012 0.0037
Echinococcus multilocularis dual specificity 0.0261 0.0171 0.1227
Trypanosoma cruzi cdc2-related kinase 1 0.0264 0.0174 0.4322
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.018 0.0095 0.056
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Plasmodium falciparum casein kinase 2, alpha subunit 0.019 0.0104 0.3155
Echinococcus multilocularis tyrosine protein kinase HCK 0.0252 0.0163 0.117
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0443 0.0344 0.2041
Echinococcus granulosus tyrosine protein kinase Src42A 0.0267 0.0178 0.1052
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0171 0.3753
Schistosoma mansoni tyrosine kinase 0.0584 0.0478 0.4821
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0475 0.0374 0.139
Entamoeba histolytica hypothetical protein 0.0093 0.0012 0.0172
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Loa Loa (eye worm) hypothetical protein 0.0096 0.0016 0.0051
Brugia malayi tRNA modification GTPase TrmE family protein 0.0104 0.0023 0.0061
Entamoeba histolytica PH domain containing protein kinase, putative 0.0309 0.0217 0.3732
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Plasmodium falciparum serine/threonine protein kinase 0.0159 0.0075 0.2233
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Onchocerca volvulus 0.0093 0.0012 0.0097
Onchocerca volvulus 0.0093 0.0012 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0748 0.0633 0.3755
Brugia malayi Protein kinase domain containing protein 0.0522 0.0419 0.1544
Entamoeba histolytica cell division protein kinase 2, putative 0.0264 0.0174 0.2986
Echinococcus granulosus PAK box P21 Rho binding 0.0098 0.0017 0.0098
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Schistosoma mansoni vesicular amine transporter 0.0181 0.0095 0.0909
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0488 0.0387 0.1438
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0343 0.0249 0.0924
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0122 0.0039 0.0791
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0087 0.0007 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.0174 0.3816
Loa Loa (eye worm) TK protein kinase 0.0644 0.0534 0.1988
Loa Loa (eye worm) TK/FER protein kinase 0.0197 0.0111 0.0405
Entamoeba histolytica protein kinase domain containing protein 0.042 0.0322 0.5549
Loa Loa (eye worm) hypothetical protein 0.0352 0.0257 0.0954
Trichomonas vaginalis AGC family protein kinase 0.042 0.0322 0.7134
Echinococcus granulosus tyrosine protein kinase Fyn 0.0431 0.0333 0.1973
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Echinococcus granulosus serine:threonine protein kinase 3 0.0475 0.0374 0.2219
Loa Loa (eye worm) hypothetical protein 0.0093 0.0012 0.0037
Trypanosoma cruzi protein kinase, putative 0.0093 0.0012 0.0196
Trichomonas vaginalis STE family protein kinase 0.0256 0.0167 0.3644
Echinococcus granulosus serine:threonine protein kinase 12 B 0.042 0.0322 0.1908
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Entamoeba histolytica cell division protein kinase 2, putative 0.0264 0.0174 0.2986
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0105 0.0024 0.0445
Onchocerca volvulus 0.0197 0.0111 0.0896
Echinococcus granulosus dual specificity 0.023 0.0143 0.0843
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Brugia malayi Immunoglobulin I-set domain containing protein 0.0115 0.0034 0.0101
Echinococcus multilocularis ephrin type A receptor 4 A 0.0209 0.0122 0.0874
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Schistosoma mansoni tyrosine kinase 0.0179 0.0094 0.0897
Entamoeba histolytica PH domain containing protein kinase, putative 0.0267 0.0177 0.3037
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0093 0.0012 0.002
Trichomonas vaginalis AGC family protein kinase 0.035 0.0256 0.5664
Entamoeba histolytica hypothetical protein 0.069 0.0578 1
Brugia malayi serine/threonine-protein kinase PAK 7 0.0909 0.0786 0.2916
Brugia malayi Protein kinase domain containing protein 0.0197 0.0111 0.0389
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0171 0.3753
Schistosoma mansoni protein kinase 0.0093 0.0012 0.0055
Echinococcus multilocularis tyrosine protein kinase pr2 0.0093 0.0012 0.0082
Echinococcus multilocularis raf serine:threonine protein kinase 0.0169 0.0084 0.0599
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0533 0.0429 0.1596
Loa Loa (eye worm) hypothetical protein 0.0148 0.0065 0.0233
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0019 0.0132
Loa Loa (eye worm) hypothetical protein 0.0263 0.0173 0.064
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Toxoplasma gondii protein kinase 0.0093 0.0012 0.0179
Loa Loa (eye worm) hypothetical protein 0.0119 0.0037 0.0132
Loa Loa (eye worm) hypothetical protein 0.0565 0.046 0.1711
Loa Loa (eye worm) hypothetical protein 0.037 0.0275 0.102
Loa Loa (eye worm) SH2 domain-containing protein 0.0104 0.0023 0.0078
Loa Loa (eye worm) CDC7 protein kinase 0.0224 0.0136 0.0502
Schistosoma mansoni kinase 0.0533 0.0429 0.4321
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0412 0.0315 0.1168
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Plasmodium falciparum calcium-dependent protein kinase 4 0.0191 0.0106 0.3194
Echinococcus multilocularis hemicentin 1 0.0087 0.0007 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0171 0.1685
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0533 0.0429 0.3079
Brugia malayi Tyrosine-protein kinase abl-1 0.0415 0.0318 0.1165
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Entamoeba histolytica protein kinase, putative 0.042 0.0322 0.5549
Loa Loa (eye worm) AGC/PKN protein kinase 0.0549 0.0444 0.1653
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Onchocerca volvulus 0.0104 0.0023 0.0185
Toxoplasma gondii protein kinase domain-containing protein 0.0093 0.0012 0.0179
Echinococcus multilocularis tyrosine kinase 0.0096 0.0016 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.0499 0.0397 0.883
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0431 0.0333 0.2386
Brugia malayi Tyrosine-protein kinase abl-1 0.0233 0.0145 0.0517
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0852 0.0732 0.5253
Onchocerca volvulus 0.0104 0.0023 0.0185
Onchocerca volvulus Serine\/threonine kinase homolog 0.0306 0.0215 0.1738
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0104 0.0023 0.0061
Loa Loa (eye worm) TK/FER protein kinase 0.0197 0.0111 0.0405
Giardia lamblia Kinase, AGC PKA 0.0293 0.0202 0.4924
Echinococcus multilocularis serine:threonine protein kinase 0.0216 0.0129 0.092
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0206 0.0119 0.0704
Schistosoma mansoni hypothetical protein 0.0185 0.01 0.0951
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0297 0.0206 0.0762
Plasmodium vivax tyrosine kinase-like protein, putative 0.0155 0.0072 0.212
Brugia malayi hypothetical protein 0.0093 0.0012 0.002
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0093 0.0012 0.0068
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0453 0.0353 0.2534
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0605 0.0498 0.1851
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.1066 0.0935 0.6711
Echinococcus multilocularis SH2 motif 0.0104 0.0023 0.016
Schistosoma mansoni shc transforming protein 0.0104 0.0023 0.0166
Echinococcus multilocularis hypothetical protein 0.0185 0.01 0.0712
Schistosoma mansoni serine/threonine kinase 0.0402 0.0306 0.3058
Leishmania major protein kinase A catalytic subunit 0.0251 0.0162 0.4004
Loa Loa (eye worm) TK protein kinase 0.0498 0.0397 0.1474
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.023 0.0143 0.3518
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0138 0.0055 0.0325
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0019 0.0341
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Onchocerca volvulus 0.0224 0.0136 0.1104
Trypanosoma cruzi casein kinase, putative 0.0206 0.0119 0.2923
Echinococcus granulosus tyrosine kinase 0.0197 0.0111 0.0653
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.037 0.0275 0.2745
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0105 0.0024 0.0445
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0191 0.0106 0.0755
Entamoeba histolytica protein kinase, putative 0.0182 0.0097 0.1649
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Loa Loa (eye worm) hypothetical protein 0.0093 0.0012 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0026 0.0201
Echinococcus granulosus serine threonine protein kinase nrc 0.0293 0.0202 0.1195
Brugia malayi Protein kinase domain containing protein 0.0224 0.0136 0.0485
Loa Loa (eye worm) hypothetical protein 0.0104 0.0023 0.0078
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus granulosus serine:threonine kinase SAD 1 0.0171 0.0086 0.0508
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0293 0.0202 0.5024
Echinococcus granulosus tyrosine protein kinase Blk 0.0356 0.0262 0.1553
Entamoeba histolytica hypothetical protein 0.0093 0.0012 0.0172
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0093 0.0012 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Brugia malayi Protein kinase c protein 2 0.0218 0.0131 0.0467
Entamoeba histolytica ankyrin repeat protein 0.0093 0.0012 0.0172
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0237 0.0149 0.0548
Echinococcus granulosus protein kinase c epsilon type 0.0392 0.0295 0.1751
Trichomonas vaginalis TKL family protein kinase 0.0095 0.0014 0.0218
Loa Loa (eye worm) hypothetical protein 0.0093 0.0012 0.0037
Trichomonas vaginalis STE family protein kinase 0.0206 0.0119 0.2578
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0293 0.0202 0.1195
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0408 0.0311 0.7794
Echinococcus multilocularis serine:threonine protein kinase 3 0.0475 0.0374 0.2684
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0251 0.0162 0.0957
Loa Loa (eye worm) TK protein kinase 0.0093 0.0012 0.0037
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.035 0.0256 0.095
Loa Loa (eye worm) hypothetical protein 0.0137 0.0054 0.0196
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0093 0.0012 0.0172
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Leishmania major serine/threonine-protein kinase, putative 0.01 0.0019 0.0386
Schistosoma mansoni hypothetical protein 0.0104 0.0023 0.0166
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0412 0.0315 0.2256
Toxoplasma gondii NEK kinase 0.01 0.0019 0.0353
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.0174 0.3816
Echinococcus granulosus tyrosine protein kinase otk 0.0087 0.0007 0.0036
Echinococcus multilocularis roundabout 2 0.0291 0.02 0.1435
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.023 0.0143 0.3106
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Brugia malayi hypothetical protein 0.0093 0.0012 0.002
Echinococcus granulosus twitchin 0.029 0.0199 0.1178
Plasmodium falciparum calcium-dependent protein kinase 5 0.0191 0.0106 0.3194
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0356 0.0262 0.1553
Giardia lamblia Aurora kinase 0.042 0.0322 0.8041
Schistosoma mansoni protein kinase 0.0443 0.0344 0.3453
Loa Loa (eye worm) hypothetical protein 0.0176 0.0091 0.0332
Echinococcus granulosus N chimaerin 0.018 0.0095 0.056
Brugia malayi Raf kinase 0.0093 0.0012 0.002
Echinococcus granulosus receptor type guanylyl cyclase 0.0096 0.0016 0.0089
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.0119 0.1151
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0179 0.0094 0.0342
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0076 0.1617
Echinococcus multilocularis 0.0342 0.0248 0.1779
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0093 0.0012 0.0082
Trypanosoma brucei protein kinase, putative 0.016 0.0076 0.1617
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.016 0.0076 0.1832
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0401 0.0304 0.1802
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0698 0.0585 0.3474
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0159 0.0075 0.1593
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0309 0.0217 0.5415
Echinococcus granulosus retinal guanylyl cyclase 2 0.0093 0.0012 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.0174 0.1714
Brugia malayi Protein kinase domain containing protein 0.0359 0.0264 0.0963
Entamoeba histolytica protein kinase, putative 0.0084 0.0004 0.0039
Echinococcus multilocularis 0.0104 0.0023 0.016
Trichomonas vaginalis AGC family protein kinase 0.042 0.0322 0.7134
Loa Loa (eye worm) TK protein kinase 0.0093 0.0012 0.0037
Echinococcus multilocularis protein tyrosine kinase 0.1012 0.0883 0.6341
Echinococcus multilocularis serine:threonine protein kinase N2 0.0549 0.0444 0.3189
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Loa Loa (eye worm) hypothetical protein 0.0092 0.0012 0.0036
Brugia malayi Cam kinase protein 1 0.0191 0.0106 0.0371
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0264 0.0174 0.0643
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0156 0.0072 0.0516
Brugia malayi hypothetical protein 0.0103 0.0021 0.0055
Brugia malayi map kinase activated protein kinase protein 2 0.0724 0.0611 0.2261
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0155 0.0072 0.1566
Brugia malayi serine/threonine protein kinase 6 0.042 0.0322 0.118
Trichomonas vaginalis AGC family protein kinase 0.0554 0.0449 1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0251 0.0162 0.1157
Echinococcus granulosus natriuretic peptide receptor 1 0.0093 0.0012 0.0068
Echinococcus granulosus tyrosine protein kinase ABL1 0.0573 0.0468 0.2774
Brugia malayi Casein kinase II, alpha chain 0.019 0.0104 0.0366
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0105 0.0024 0.0445
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0075 0.0702
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0096 0.0016 0.0127
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Trichomonas vaginalis CMGC family protein kinase 0.0224 0.0136 0.2966
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0162 0.0078 0.1872
Schistosoma mansoni protein kinase 0.0166 0.0082 0.0768
Echinococcus granulosus retinal guanylyl cyclase 2 0.0093 0.0012 0.0068
Giardia lamblia Kinase, CMGC CLK 0.0343 0.0249 0.6159
Brugia malayi SH2 domain containing protein 0.0748 0.0633 0.2343
Echinococcus multilocularis c src tyrosine kinase 0.0271 0.0181 0.1298
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.018 0.0095 0.0902
Echinococcus multilocularis tyrosine protein kinase csk 0.0093 0.0012 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0104 0.0023 0.0185
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0499 0.0397 1
Echinococcus multilocularis insulin receptor 0.0824 0.0705 0.5059
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0408 0.0311 0.7128
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0191 0.0106 0.0387
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0253 0.0164 0.1173
Loa Loa (eye worm) TK/ALK protein kinase 0.0522 0.0419 0.1558
Loa Loa (eye worm) TK/RYK protein kinase 0.0093 0.0012 0.0037
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0161 0.0077 0.1625
Schistosoma mansoni serine/threonine protein kinase 0.0373 0.0278 0.2772
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0306 0.0215 0.2127
Echinococcus multilocularis mitogen activated protein kinase 3 0.016 0.0076 0.0544
Echinococcus multilocularis neural Wiskott Aldrich syndrome protein 0.0098 0.0017 0.0118
Loa Loa (eye worm) hypothetical protein 0.0216 0.0129 0.0473
Trypanosoma cruzi cdc2-related kinase 3 0.0264 0.0174 0.4322
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0191 0.0106 0.0371
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.1066 0.0935 0.5548
Trichomonas vaginalis AGC family protein kinase 0.042 0.0322 0.7134
Schistosoma mansoni nck2/grb4 0.0179 0.0094 0.089
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0019 0.0341
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0206 0.0119 0.0438
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0087 0.0007 0.0054
Entamoeba histolytica PH domain containing protein kinase, putative 0.0267 0.0177 0.3037
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Giardia lamblia Kinase, AGC PKA 0.0251 0.0162 0.3884
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Onchocerca volvulus 0.0116 0.0034 0.0279
Echinococcus granulosus tyrosine protein kinase 0.0528 0.0425 0.2519
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Trypanosoma brucei cdc2-related kinase 3 0.0264 0.0174 0.3816
Echinococcus granulosus activated cdc42 kinase 1 0.0093 0.0012 0.0068
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0756 0.064 0.3801
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Trichomonas vaginalis protein kinase atn1, putative 0.0093 0.0012 0.0173
Trichomonas vaginalis CK1 family protein kinase 0.0206 0.0119 0.2581
Echinococcus granulosus mitogen activated protein kinase 0.016 0.0076 0.045
Entamoeba histolytica hypothetical protein 0.0093 0.0012 0.0172
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0093 0.0012 0.0037
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0191 0.0106 0.3194
Trichomonas vaginalis CAMK family protein kinase 0.0499 0.0397 0.883
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0171 0.3753
Loa Loa (eye worm) AUR protein kinase 0.042 0.0322 0.1195
Leishmania major protein kinase, putative 0.01 0.0019 0.0386
Entamoeba histolytica serine/threonine kinase, putative 0.0093 0.0012 0.0172
Echinococcus multilocularis serine:threonine protein kinase N2 0.0313 0.0221 0.1585
Echinococcus multilocularis neuroglian 0.0222 0.0134 0.0961
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Loa Loa (eye worm) TK/FER protein kinase 0.0197 0.0111 0.0405
Giardia lamblia Kinase, PLK 0.0499 0.0397 1
Schistosoma mansoni serine/threonine protein kinase 0.0466 0.0366 0.3675
Echinococcus multilocularis tensin 0.0104 0.0023 0.016
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0093 0.0012 0.0082
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0343 0.0249 0.5505
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0012 0.0173
Onchocerca volvulus 0.0104 0.0023 0.0185
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0159 0.0075 0.0273
Leishmania major casein kinase, putative 0.0206 0.0119 0.2923
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0093 0.0012 0.002
Loa Loa (eye worm) SH2 domain-containing protein 0.0104 0.0023 0.0078
Loa Loa (eye worm) TK protein kinase 0.0528 0.0425 0.1579
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0179 0.0094 0.089
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0264 0.0174 0.3953
Trichomonas vaginalis AGC family protein kinase 0.0256 0.0167 0.3644
Loa Loa (eye worm) AGC/PKA protein kinase 0.0251 0.0162 0.0596
Brugia malayi MAP kinase sur-1 0.016 0.0076 0.0261
Entamoeba histolytica hypothetical protein 0.0084 0.0004 0.0039
Loa Loa (eye worm) hypothetical protein 0.016 0.0076 0.0276
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0162 0.1586
Schistosoma mansoni tensin 0.0104 0.0023 0.0166
Onchocerca volvulus 0.0224 0.0136 0.1104
Echinococcus granulosus tyrosine protein kinase Lyn 0.0499 0.0397 0.2357
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0012 0.0173
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0108 0.0026 0.0558
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0093 0.0012 0.0172
Echinococcus granulosus expressed conserved protein 0.0104 0.0023 0.0132
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Echinococcus multilocularis death associated protein kinase 1 0.1549 0.1392 1
Entamoeba histolytica protein kinase, putative 0.023 0.0143 0.2438
Leishmania major protein kinase, putative 0.0343 0.0249 0.6234
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0182 0.0097 0.0693
Entamoeba histolytica hypothetical protein 0.0093 0.0012 0.0172
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0093 0.0012 0.0068
Loa Loa (eye worm) hypothetical protein 0.0252 0.0163 0.0602
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0171 0.0086 0.208
Loa Loa (eye worm) RGC/RGC protein kinase 0.0096 0.0016 0.0051
Loa Loa (eye worm) RGC/RGC protein kinase 0.0096 0.0016 0.0051
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0012 0.0055
Leishmania major protein kinase, putative 0.042 0.0322 0.8079
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.0221 0.2195
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0343 0.0249 0.6234
Onchocerca volvulus 0.0093 0.0012 0.0097
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0018 0.0106
Schistosoma mansoni biogenic amine (5HT) receptor 0.016 0.0076 0.0709
Schistosoma mansoni nephrin 0.025 0.0161 0.1581
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Echinococcus multilocularis nervana 2 0.0225 0.0137 0.0981
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0104 0.0023 0.016
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Entamoeba histolytica protein kinase domain containing protein 0.023 0.0143 0.2438
Loa Loa (eye worm) hypothetical protein 0.0162 0.0078 0.0283
Entamoeba histolytica protein kinase, putative 0.023 0.0143 0.2438
Echinococcus granulosus serine/threonine protein kinase 0.0309 0.0217 0.1286
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0104 0.0023 0.0166
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0796 0.0679 0.403
Schistosoma mansoni tyrosine kinase 0.0648 0.0538 0.5439
Loa Loa (eye worm) hypothetical protein 0.0655 0.0545 0.2029
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus granulosus SH2 domain containing adapter protein F 0.0104 0.0023 0.0132
Schistosoma mansoni protein kinase 0.0093 0.0012 0.0055
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Echinococcus granulosus nervana 2 0.0225 0.0137 0.0811
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0084 0.0791
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0251 0.0162 0.4956
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0293 0.0202 0.6218
Entamoeba histolytica hypothetical protein 0.0091 0.001 0.0144
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.001 0.0068
Echinococcus multilocularis serine:threonine protein kinase 38 0.0313 0.0221 0.1585
Entamoeba histolytica serine/threonine kinase, putative 0.0093 0.0012 0.0172
Echinococcus multilocularis protein kinase 0.0093 0.0012 0.0082
Leishmania major protein kinase, putative 0.0191 0.0106 0.2581
Loa Loa (eye worm) thyroid receptor interactor 0.0212 0.0126 0.0462
Entamoeba histolytica protein kinase, putative 0.0313 0.0221 0.3802
Giardia lamblia Kinase, CMGC GSK 0.0408 0.0311 0.775
Echinococcus multilocularis roundabout 2 0.0115 0.0034 0.0237
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0251 0.0162 0.058
Echinococcus multilocularis calcium dependent protein kinase 0.0123 0.0041 0.0291
Brugia malayi SH2 domain containing protein 0.0197 0.0111 0.0389
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0012 0.0173
Brugia malayi Protein kinase domain containing protein 0.0197 0.0111 0.0389
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0251 0.0162 0.3536
Echinococcus granulosus cGMP dependent protein kinase 1 0.0253 0.0164 0.097
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0098 0.0017 0.0056
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0162 0.0078 0.0283
Trypanosoma brucei SNF1-related protein kinases, putative 0.0171 0.0086 0.1837
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Entamoeba histolytica serine/threonine kinase, putative 0.0093 0.0012 0.0172
Echinococcus multilocularis tensin 0.0104 0.0023 0.016
Onchocerca volvulus 0.0147 0.0063 0.0511
Schistosoma mansoni protein kinase C mu 0.0404 0.0307 0.3069
Brugia malayi Receptor family ligand binding region containing protein 0.0096 0.0016 0.0034
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0176 0.0091 0.065
Brugia malayi Egg laying defective protein 4 0.0253 0.0164 0.0588
Echinococcus granulosus cGMP dependent protein kinase 0.0253 0.0164 0.097
Echinococcus multilocularis mitogen activated protein kinase 0.016 0.0076 0.0544
Schistosoma mansoni serine/threonine protein kinase 0.0549 0.0444 0.4477
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Brugia malayi Protein kinase domain containing protein 0.0156 0.0072 0.0246
Schistosoma mansoni hypothetical protein 0.0104 0.0023 0.0166
Trypanosoma brucei Flagellum attachment zone protein 20 0.0093 0.0012 0.0173
Schistosoma mansoni adapter molecule crk 0.0179 0.0094 0.089
Echinococcus multilocularis serotonin receptor 0.016 0.0076 0.0541
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0108 0.0026 0.009
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Loa Loa (eye worm) hypothetical protein 0.0204 0.0118 0.0433
Schistosoma mansoni protein kinase 0.0359 0.0264 0.2633
Schistosoma mansoni vam6/vps39 related 0.0226 0.0139 0.135
Echinococcus granulosus activin receptor type 0.0161 0.0077 0.0452
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.019 0.0104 0.0383
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0093 0.0012 0.0082
Echinococcus multilocularis cyclin dependent kinase 1 0.0264 0.0174 0.1247
Giardia lamblia Kinase, NEK 0.0256 0.0167 0.4009
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0264 0.0174 0.4322
Onchocerca volvulus 0.0197 0.0111 0.0896
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0093 0.0012 0.0179
Brugia malayi bone morphogenetic protein type 1 receptor 0.0093 0.0012 0.002
Brugia malayi hypothetical protein 0.0412 0.0315 0.1153
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0137 0.0054 0.0318
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0191 0.0106 0.0624
Entamoeba histolytica tyrosin kinase, putative 0.0093 0.0012 0.0172
Onchocerca volvulus Huntingtin homolog 0.0119 0.0037 0.0302
Echinococcus multilocularis netrin receptor unc 5 0.0094 0.0013 0.009
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0156 0.0072 0.0426
Echinococcus multilocularis mitogen activated protein kinase 11 0.0297 0.0206 0.1476
Schistosoma mansoni tyrosine kinase 0.0093 0.0012 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0072 0.0673
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0164 0.1612
Echinococcus granulosus hemicentin 1 0.0087 0.0007 0.0036
Schistosoma mansoni tyrosine kinase 0.1119 0.0984 1
Plasmodium vivax serine/threonine protein kinase 6, putative 0.042 0.0322 1
Onchocerca volvulus 0.0093 0.0012 0.0097
Echinococcus multilocularis tyrosine protein kinase Abl 0.0415 0.0318 0.2279
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus multilocularis protein KINase family member (kin 25) 0.0093 0.0012 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Leishmania major protein kinase, putative 0.0162 0.0078 0.1872
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0093 0.0012 0.0037
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0263 0.0173 0.064
Echinococcus granulosus Glutaredoxin protein 5 0.0225 0.0137 0.0811
Mycobacterium ulcerans AcrR family transcriptional regulator 1.0633 1 1
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0217 0.013 0.0769
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0019 0.0341
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0018 0.0044
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0466 0.0366 0.2625
Entamoeba histolytica protein kinase, putative 0.0261 0.0171 0.2938
Echinococcus granulosus tyrosine protein kinase Srms 0.0937 0.0812 0.4822
Loa Loa (eye worm) SRC-1 0.0431 0.0333 0.1235
Loa Loa (eye worm) TK/ROR protein kinase 0.0138 0.0055 0.0199
Brugia malayi Protein kinase domain containing protein 0.0353 0.0259 0.0945
Echinococcus multilocularis titin 0.0142 0.0059 0.042
Entamoeba histolytica serine/threonine kinase, putative 0.0093 0.0012 0.0172
Echinococcus multilocularis lachesin 0.0087 0.0007 0.0043
Entamoeba histolytica protein kinase domain containing protein 0.0533 0.0429 0.7411
Echinococcus multilocularis epidermal growth factor receptor 0.1119 0.0984 0.707
Trichomonas vaginalis CAMK family protein kinase 0.0217 0.013 0.283
Echinococcus granulosus expressed protein 0.0159 0.0075 0.0443
Onchocerca volvulus 0.0093 0.0012 0.0097
Schistosoma mansoni hypothetical protein 0.0171 0.0086 0.0815
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0488 0.0387 0.389
Onchocerca volvulus 0.0093 0.0012 0.0097
Echinococcus multilocularis activated cdc42 kinase 1 0.0093 0.0012 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0724 0.0611 0.6177
Brugia malayi hypothetical protein 0.0104 0.0023 0.0061
Schistosoma mansoni tyrosine kinase 0.0741 0.0626 0.6336
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Onchocerca volvulus 0.0912 0.0789 0.6388
Entamoeba histolytica serine/threonine kinase, putative 0.0093 0.0012 0.0172
Loa Loa (eye worm) hypothetical protein 0.0191 0.0106 0.0387
Loa Loa (eye worm) AUR protein kinase 0.042 0.0322 0.1195
Echinococcus granulosus tyrosine protein kinase Fyn 0.0431 0.0333 0.1973
Schistosoma mansoni protein kinase 0.0796 0.0679 0.6876
Schistosoma mansoni tyrosine kinase 0.0191 0.0105 0.1004
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Entamoeba histolytica protein kinase, putative 0.0084 0.0004 0.0039
Echinococcus multilocularis geminin 0.0171 0.0086 0.0616
Echinococcus granulosus dual specificity protein kinase clk2 0.0343 0.0249 0.1477
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.042 0.0322 0.5549
Brugia malayi putative serine/threonine kinase SADA gamma 0.0171 0.0086 0.0297
Trypanosoma cruzi protein kinase, putative 0.0093 0.0012 0.0196
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Trichomonas vaginalis STE family protein kinase 0.0162 0.0078 0.1653
Trichomonas vaginalis AGC family protein kinase 0.0554 0.0449 1
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0251 0.0162 0.4956
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0093 0.0012 0.0172
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0093 0.0012 0.0097
Brugia malayi intracellular kinase 0.0408 0.0311 0.1138
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.0106 0.1014
Trichomonas vaginalis AGC family protein kinase 0.0156 0.0072 0.153
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0104 0.0023 0.0185
Loa Loa (eye worm) hypothetical protein 0.0259 0.017 0.0628
Schistosoma mansoni nephrin 0.0115 0.0034 0.0276
Schistosoma mansoni suppressor of cytokine signaling 0.0104 0.0023 0.0166
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.01 0.0019 0.0386
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Plasmodium vivax unspecified product 0.019 0.0104 0.3155
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1066 0.0935 0.3484
Trichomonas vaginalis CMGC family protein kinase 0.0224 0.0136 0.2966
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Brugia malayi SH2 domain containing protein 0.0104 0.0023 0.0061
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0251 0.0162 0.0957
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0538 0.0434 0.1614
Toxoplasma gondii casein kinase I 0.0206 0.0119 0.2674
Trypanosoma cruzi cdc2-related kinase 3 0.0264 0.0174 0.4322
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0138 0.0055 0.0393
Echinococcus granulosus fibroblast growth factor receptor 4 0.0453 0.0353 0.2095
Brugia malayi cytokine inducible SH2-containing protein 5 0.0104 0.0023 0.0061
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus granulosus dual specificity 0.0261 0.0171 0.1014
Echinococcus granulosus SH2 motif 0.0104 0.0023 0.0132
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.042 0.0322 0.5549
Entamoeba histolytica protein kinase, putative 0.0408 0.0311 0.5354
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0261 0.0171 0.3753
Echinococcus granulosus serine:threonine protein kinase N2 0.0235 0.0147 0.0872
Trichomonas vaginalis AGC family protein kinase 0.0554 0.0449 1
Brugia malayi Protein kinase domain containing protein 0.0373 0.0278 0.1015
Entamoeba histolytica protein kinase domain containing protein 0.0161 0.0077 0.1294
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Brugia malayi ephrin receptor 1 precursor 0.0147 0.0064 0.0215
Echinococcus granulosus suppressor of cytokine signaling 6 0.0104 0.0023 0.0132
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Brugia malayi serine/threonine-protein kinase 6 0.042 0.0322 0.118
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Loa Loa (eye worm) TK/FER protein kinase 0.0093 0.0012 0.0037
Echinococcus multilocularis serine:threonine protein kinase 0.0216 0.0129 0.092
Echinococcus granulosus mitogen activated protein kinase 11 0.0297 0.0206 0.122
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.0106 0.2279
Echinococcus multilocularis cyclin dependent kinase 5 0.0264 0.0174 0.1247
Echinococcus granulosus SHC transforming protein 3 0.0104 0.0023 0.0132
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Mycobacterium ulcerans TetR family transcriptional regulator 1.0633 1 1
Onchocerca volvulus 0.0197 0.0111 0.0896
Entamoeba histolytica hypothetical protein 0.0098 0.0017 0.0261
Entamoeba histolytica PH domain containing protein kinase, putative 0.0309 0.0217 0.3732
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0226 0.0139 0.0992
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Trichomonas vaginalis CMGC family protein kinase 0.0343 0.0249 0.5505
Schistosoma mansoni growth factor receptor-bound protein 0.0179 0.0094 0.089
Brugia malayi C-terminal src kinase protein 1 0.0093 0.0012 0.002
Entamoeba histolytica tyrosine kinase, putative 0.0093 0.0012 0.0172
Brugia malayi Serotonin/octopamine receptor family protein 7 0.037 0.0275 0.1005
Echinococcus granulosus mitogen activated protein kinase 14 0.0297 0.0206 0.122
Brugia malayi Variant SH3 domain containing protein 0.018 0.0095 0.033
Trichomonas vaginalis AGC family protein kinase 0.0313 0.0221 0.4873
Plasmodium falciparum protein kinase, putative 0.0161 0.0077 0.2278
Loa Loa (eye worm) hypothetical protein 0.0093 0.0012 0.0037
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.01 0.0019 0.0478
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Loa Loa (eye worm) hypothetical protein 0.012 0.0038 0.0135
Loa Loa (eye worm) TK/Met protein kinase 0.0093 0.0012 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0498 0.0397 0.1459
Loa Loa (eye worm) AGC/PKG protein kinase 0.0253 0.0164 0.0604
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Schistosoma mansoni protein kinase 0.0796 0.0679 0.6876
Loa Loa (eye worm) TK/FER protein kinase 0.0093 0.0012 0.0037
Echinococcus granulosus serine:threonine protein kinase mig 15 0.05 0.0398 0.2361
Brugia malayi Protein kinase domain containing protein 0.0823 0.0704 0.2611
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0026 0.0201
Loa Loa (eye worm) hypothetical protein 0.0177 0.0092 0.0334
Trichomonas vaginalis STE family protein kinase 0.0093 0.0012 0.0173
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0091 0.001 0.0039
Entamoeba histolytica hypothetical protein 0.0093 0.0012 0.0172
Entamoeba histolytica hypothetical protein 0.0093 0.0013 0.0181
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0019 0.0341
Echinococcus granulosus titin 0.0142 0.0059 0.0348
Echinococcus granulosus SH2 motif 0.0104 0.0023 0.0132
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0251 0.0162 0.3536
Echinococcus multilocularis peroxidasin 0.0087 0.0007 0.0047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.001 0.0035
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0104 0.2251
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0096 0.0015 0.0107
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0137 0.0055 0.1279
Plasmodium falciparum protein kinase, putative 0.0093 0.0012 0.0243
Brugia malayi Furin-like cysteine rich region family protein 0.1119 0.0984 0.366
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0086 0.1837
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0217 0.013 0.077
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0179 0.0094 0.0342
Schistosoma mansoni protein kinase 0.042 0.0322 0.3224
Loa Loa (eye worm) hypothetical protein 0.0197 0.0111 0.0405
Echinococcus granulosus serine:threonine protein kinase 0.0216 0.0129 0.076
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0306 0.0215 0.1271
Leishmania major hypothetical protein, conserved 0.0093 0.0012 0.0196
Brugia malayi Temporarily assigned gene name protein 59 0.0234 0.0146 0.0523
Loa Loa (eye worm) STAT protein 0.0104 0.0023 0.0078
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0093 0.0012 0.0172
Echinococcus multilocularis 0.0275 0.0185 0.1323
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0724 0.0611 0.2274
Loa Loa (eye worm) TK/FER protein kinase 0.0093 0.0012 0.0037
Brugia malayi phosphoinositide-dependent protein kinase I 0.0156 0.0072 0.0246
Entamoeba histolytica casein kinase 1, putative 0.0206 0.0119 0.2032
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0093 0.0012 0.0037
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Echinococcus granulosus SH2 domain containing protein 7 0.0104 0.0023 0.0132
Schistosoma mansoni tyrosine kinase 0.0093 0.0012 0.0055
Plasmodium falciparum tyrosine kinase-like protein 0.0093 0.0012 0.0243
Schistosoma mansoni protein kinase 0.019 0.0104 0.1001
Trichomonas vaginalis CK1 family protein kinase 0.0206 0.0119 0.2581
Loa Loa (eye worm) hypothetical protein 0.0195 0.011 0.0402
Trichomonas vaginalis AGC family protein kinase 0.0554 0.0449 1
Trichomonas vaginalis AGC family protein kinase 0.0367 0.0272 0.6009
Onchocerca volvulus 0.0197 0.0111 0.0896
Echinococcus multilocularis serine:threonine protein kinase N2 0.0235 0.0147 0.1055
Schistosoma mansoni serine/threonine protein kinase 0.0396 0.0299 0.2992
Trichomonas vaginalis AGC family protein kinase 0.0122 0.0039 0.0791
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0466 0.0366 0.136
Schistosoma mansoni tyrosine kinase 0.0093 0.0012 0.0055
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0251 0.0162 0.4004
Entamoeba histolytica hypothetical protein 0.0084 0.0004 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0499 0.0397 0.883
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Loa Loa (eye worm) hypothetical protein 0.0087 0.0007 0.0019
Loa Loa (eye worm) RGC/RGC protein kinase 0.0096 0.0016 0.0051
Echinococcus multilocularis myosin iiia 0.0162 0.0078 0.0555
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0059 0.0537
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.01 0.0019 0.0341
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0161 0.0077 0.1683
Echinococcus granulosus myotubularin protein 13 0.0092 0.0012 0.0066
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0115 0.0034 0.0276
Echinococcus granulosus aurora kinase A 0.042 0.0322 0.1908
Giardia lamblia Kinase, AGC AKT 0.0221 0.0134 0.3157
Loa Loa (eye worm) TK/FER protein kinase 0.0197 0.0111 0.0405
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0909 0.0786 0.2928
Schistosoma mansoni protein kinase 0.0698 0.0585 0.592
Brugia malayi Protein kinase domain containing protein 0.036 0.0266 0.0969
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Schistosoma mansoni protein kinase 0.0093 0.0012 0.0055
Brugia malayi Hr1 repeat family protein 0.0549 0.0444 0.1638
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0191 0.0106 0.0624
Loa Loa (eye worm) hypothetical protein 0.0104 0.0023 0.0078
Brugia malayi STE20-like kinase MST 0.0475 0.0374 0.1376
Trypanosoma cruzi polo-like protein kinase, putative 0.0499 0.0397 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0098 0.0017 0.0055
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0698 0.0585 0.218
Echinococcus multilocularis SH2 motif 0.0104 0.0023 0.016
Onchocerca volvulus 0.1245 0.1104 0.8939
Entamoeba histolytica cysteine surface protein, putative 0.0093 0.0012 0.0172
Loa Loa (eye worm) hypothetical protein 0.0179 0.0094 0.0342
Brugia malayi protein kinase C II. 0.0392 0.0295 0.1081
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0104 0.0023 0.0132
Brugia malayi Protein kinase domain containing protein 0.0698 0.0585 0.2166
Echinococcus multilocularis SH2 domain containing protein 7 0.0104 0.0023 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0095 0.0014 0.0218
Echinococcus multilocularis heat shock protein 70 0.0093 0.0012 0.0082
Loa Loa (eye worm) hypothetical protein 0.05 0.0398 0.1479
Echinococcus multilocularis casein kinase I alpha 0.0206 0.0119 0.0852
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.01 0.0019 0.0386
Schistosoma mansoni tensin 0.0104 0.0023 0.0166
Schistosoma mansoni protein kinase 0.0443 0.0344 0.3453
Loa Loa (eye worm) hypothetical protein 0.0093 0.0012 0.0037
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0159 0.0075 0.165
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0123 0.004 0.0143
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0093 0.0012 0.0173
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Schistosoma mansoni tyrosine kinase 0.0685 0.0573 0.5794
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0024 0.0445
Echinococcus multilocularis tyrosine protein kinase csk 0.0093 0.0012 0.0082
Echinococcus multilocularis mitogen activated protein kinase 11 0.0297 0.0206 0.1476
Schistosoma mansoni tyrosine kinase 0.0824 0.0705 0.7139
Entamoeba histolytica protein kinase, putative 0.0093 0.0013 0.0181
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0093 0.0012 0.0172
Plasmodium vivax calcium-dependent protein kinase, putative 0.0191 0.0106 0.3194
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.016 0.0076 0.1832
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0251 0.0162 0.1157
Trichomonas vaginalis AGC family protein kinase 0.0251 0.0162 0.3536
Schistosoma mansoni protein kinase 0.0098 0.0017 0.0107
Giardia lamblia Kinase, CMGC CDK 0.0264 0.0174 0.4208
Loa Loa (eye worm) hypothetical protein 0.0104 0.0023 0.0078
Giardia lamblia Kinase, CDC7 0.0224 0.0136 0.3226
Schistosoma mansoni protein kinase 0.0093 0.0012 0.0055
Brugia malayi Tensin 0.0104 0.0023 0.0061
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0093 0.0012 0.002
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1066 0.0935 0.3484
Echinococcus multilocularis PAK box P21 Rho binding 0.0098 0.0017 0.0118
Brugia malayi Variant SH3 domain containing protein 0.0179 0.0094 0.0326
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0748 0.0633 0.4542
Echinococcus multilocularis casein kinase I alpha 0.0206 0.0119 0.0852
Brugia malayi SH2 domain containing protein 0.0104 0.0023 0.0061
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0176 0.0091 0.0863
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0306 0.0215 0.1538
Entamoeba histolytica hypothetical protein 0.0098 0.0017 0.0261
Entamoeba histolytica protein kinase, putative 0.0172 0.0087 0.1482
Onchocerca volvulus 0.0093 0.0012 0.0097
Echinococcus granulosus tyrosine protein kinase csk 0.0093 0.0012 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0216 0.0129 0.2792
Loa Loa (eye worm) TK/EGFR protein kinase 0.1119 0.0984 0.3671
Loa Loa (eye worm) hypothetical protein 0.0171 0.0086 0.0314
Echinococcus granulosus integrin linked protein kinase 0.0093 0.0012 0.0068
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0191 0.0106 0.236
Echinococcus granulosus tyrosine protein kinase Src64B 0.0431 0.0333 0.1973
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0093 0.0012 0.0172
Entamoeba histolytica hypothetical protein 0.0093 0.0013 0.0181
Brugia malayi Protein kinase domain containing protein 0.0093 0.0012 0.002
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0346 0.0252 0.1806
Schistosoma mansoni tyrosine kinase 0.0096 0.0016 0.0092
Trypanosoma brucei Pseudokinase, putative 0.0093 0.0012 0.0173
Schistosoma mansoni tyrosine kinase 0.0093 0.0012 0.0055
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0343 0.0249 0.5702
Loa Loa (eye worm) hypothetical protein 0.0087 0.0007 0.0017
Onchocerca volvulus 0.0093 0.0012 0.0097
Echinococcus multilocularis activin receptor type 0.0161 0.0077 0.0546
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.001 0.0035
Toxoplasma gondii STE kinase 0.0093 0.0012 0.0179
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0164 0.1612
Schistosoma mansoni tyrosine kinase 0.0271 0.0181 0.1787
Echinococcus multilocularis tyrosine protein kinase shark 0.0584 0.0478 0.3431
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0093 0.0012 0.0037
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0811 0.0693 0.4113
Trypanosoma cruzi casein kinase, putative 0.0206 0.0119 0.2923
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0237 0.0149 0.3683
Schistosoma mansoni netrin receptor unc5 0.0094 0.0013 0.0066
Onchocerca volvulus 0.0408 0.0311 0.2516
Echinococcus granulosus biogenic amine 5HT receptor 0.016 0.0076 0.0448
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1098 0.0965 0.3597
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0756 0.064 0.4598
Trypanosoma brucei casein kinase I, isoform 2 0.0206 0.0119 0.2581
Brugia malayi protein kinase C3,putative 0.0295 0.0204 0.0737
Loa Loa (eye worm) hypothetical protein 0.0176 0.0091 0.0332
Loa Loa (eye worm) serine/threonine protein kinase 0.0093 0.0012 0.0037
Brugia malayi Fibronectin type III domain containing protein 0.0204 0.0118 0.0417
Giardia lamblia Kinase, CMGC DYRK 0.0261 0.0171 0.4136
Echinococcus granulosus protein tyrosine kinase 0.1012 0.0883 0.5242
Echinococcus multilocularis nervana 2 0.0225 0.0137 0.0981
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0104 0.0023 0.0132
Trichomonas vaginalis AGC family protein kinase 0.0554 0.0449 1
Schistosoma mansoni serine/threonine protein kinase 0.0343 0.0249 0.2482
Trichomonas vaginalis TKL family protein kinase 0.0093 0.0012 0.0173
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0818 0.07 0.5022
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Loa Loa (eye worm) TK/CSK protein kinase 0.0093 0.0012 0.0037
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0206 0.0119 0.0851
Mycobacterium tuberculosis Transcriptional regulatory repressor protein (TetR-family) EthR 1.0633 1 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0267 0.0178 0.1272
Entamoeba histolytica protein kinase, putative 0.0093 0.0012 0.0172
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2907 0.2679 1
Loa Loa (eye worm) hypothetical protein 0.0251 0.0162 0.0596
Schistosoma mansoni suppressor of cytokine signaling 0.0104 0.0023 0.0166
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.018 0.0095 0.0902
Echinococcus multilocularis tyrosine protein kinase csk 0.0093 0.0012 0.0082
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0012 0.0172
Loa Loa (eye worm) hypothetical protein 0.0119 0.0037 0.0132

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) 0 uM kg-1 The compound was tested in vivo for biochemical effect against the changes in different brain area levels of DOPA in reserpinized rat limbic systemat dose 12.5 microM/kg; Partial effect ChEMBL. 7783153
ED50 (functional) 0 uM kg-1 The compound was tested in vivo for biochemical effect against the changes in different brain area levels of DOPA in reserpinized rat corpus striatum at dose 12.5 microM/kg; Inactive ChEMBL. 7783153
ED50 (functional) 0 uM kg-1 The compound was tested in vivo for biochemical effect against the changes in different brain area levels of DOPA in reserpinized rat hemispheres(mainly cortex)at dose 12.5 microM/kg; Inactive ChEMBL. 7783153
ED50 (functional) = 0.16 uM kg-1 In vivo changes in different brain area levels of 5-HTP in reserpinized rat corpus striatum. ChEMBL. 7783153
ED50 (functional) = 0.19 uM kg-1 In vivo changes in different brain area levels of 5-HTP in reserpinized rat limbic system. ChEMBL. 7783153
ED50 (functional) = 0.19 uM kg-1 In vivo for biochemical effect against brain area levels of 5-HTP in reserpinized rat hemispheres(mainly cortex). ChEMBL. 7783153
Ki (binding) nM In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]-5-HT as radioligand ChEMBL. 7783153
Ki (binding) 0 nM In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]-5-HT as radioligand ChEMBL. 7783153
Ki (binding) = 0.3 nM In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]-8-OH-DPAT as radioligand. ChEMBL. 7783153
Ki (binding) = 0.3 nM In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]-8-OH-DPAT as radioligand. ChEMBL. 7783153
Ki (binding) = 49 nM In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor beta expressed in CHO cells, by using [3H]-5-HT as radioligand ChEMBL. 7783153
Ki (binding) = 49 nM In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor beta expressed in CHO cells, by using [3H]-5-HT as radioligand ChEMBL. 7783153
Ki (binding) = 59 nM In vitro binding affinity against cloned mammalian Dopamine receptor D2 expressed in CHO cells using [3H]-U-86,170 as radioligand ChEMBL. 7783153
Ki (binding) = 59 nM In vitro binding affinity against cloned mammalian Dopamine receptor D2 expressed in CHO cells using [3H]-U-86,170 as radioligand ChEMBL. 7783153
Ki (binding) = 130 nM In vitro binding affinity against cloned mammalian Dopamine receptor D3 expressed in CHO cells by, using [3H]-spiperone as radioligand ChEMBL. 7783153
Ki (binding) = 130 nM In vitro binding affinity against cloned mammalian Dopamine receptor D3 expressed in CHO cells by, using [3H]-spiperone as radioligand ChEMBL. 7783153

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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