Detailed information for compound 1179849

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 502.085 | Formula: C29H40ClNO4
  • H donors: 2 H acceptors: 2 LogP: 4.84 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: CO[C@]12CC[C@]3(C[C@@H]1[C@](C1CCC1)(O)C)[C@@]14[C@H]2Oc2c4c(CC3N(CC1)CC1CC1)ccc2O.Cl
  • InChi: 1S/C29H39NO4.ClH/c1-26(32,19-4-3-5-19)21-15-27-10-11-29(21,33-2)25-28(27)12-13-30(16-17-6-7-17)22(27)14-18-8-9-20(31)24(34-25)23(18)28;/h8-9,17,19,21-22,25,31-32H,3-7,10-16H2,1-2H3;1H/t21-,22?,25-,26+,27-,28+,29-;/m1./s1
  • InChiKey: HTCUOPOUBUNMFJ-GVBWWAFJSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens opioid receptor, kappa 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus zinc finger protein 0.0092 0.0091 0.009
Echinococcus multilocularis conserved hypothetical protein 0.0187 0.0221 0.022
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0054 0.0039 0.0143
Brugia malayi Thioredoxin reductase 0.0083 0.0079 0.0115
Loa Loa (eye worm) RGC/RGC protein kinase 0.0149 0.017 0.0249
Entamoeba histolytica hypothetical protein 0.0114 0.0122 0.1388
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0403 0.0518 0.0765
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0027 0.0101
Onchocerca volvulus 0.0058 0.0044 0.0155
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0002 0.0001
Echinococcus granulosus sodium leak channel non selective protein 0.0187 0.0221 0.022
Echinococcus granulosus neuroligin 0.0054 0.004 0.0038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0248 0.0305 0.0304
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0103 0.0106 0.0105
Echinococcus multilocularis geminin 0.0886 0.1179 0.1178
Leishmania major hypothetical protein, conserved 0.0217 0.0262 0.7171
Brugia malayi Carboxylesterase family protein 0.0054 0.004 0.0057
Echinococcus granulosus g protein coupled receptor 0.0027 0.0002 0.0001
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0187 0.0221 0.0325
Echinococcus multilocularis glutamate receptor 2 0.0291 0.0364 0.0363
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0001 0.0004
Trichomonas vaginalis hypothetical protein 0.0026 0.0001 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.011 0.0408
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0033 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis transcription factor Dp 1 0.0123 0.0133 0.0132
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0002 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.003 0.0111
Onchocerca volvulus 0.0054 0.004 0.0139
Loa Loa (eye worm) glutamate receptor 2 0.0291 0.0364 0.0537
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0292 0.0365 1
Entamoeba histolytica hypothetical protein 0.01 0.0102 0.1168
Treponema pallidum bacterioferrin (TpF1) 0.0107 0.0112 0.1096
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0187 0.0221 0.0325
Brugia malayi Muscleblind-like protein 0.0951 0.1267 0.1874
Echinococcus granulosus peregrin 0.0041 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.01 0.0103 0.015
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.001 0.0013
Brugia malayi Metabotropic glutamate receptor precursor. 0.0149 0.017 0.0249
Echinococcus granulosus intermediate filament protein 0.0172 0.0201 0.02
Onchocerca volvulus Bile acid receptor homolog 0.0033 0.001 0.0028
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0099
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0106 0.011 0.2995
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0054 0.0039 0.0143
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0212 0.0255 0.6992
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0187 0.0221 0.0219
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0075 0.0068 0.0067
Echinococcus multilocularis ryanodine receptor 44f 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Onchocerca volvulus 0.0217 0.0262 0.0963
Loa Loa (eye worm) hypothetical protein 0.0217 0.0262 0.0386
Schistosoma mansoni calcium-activated potassium channel 0.0187 0.0221 0.0219
Trichomonas vaginalis helicase, putative 0.0048 0.0031 0.0116
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0149 0.017 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0002 0.0001
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0106 0.011 0.1998
Schistosoma mansoni metabotropic glutamate receptor 0.0149 0.017 0.0167
Loa Loa (eye worm) doublecortin family protein 0.0089 0.0087 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0248 0.0305 0.0302
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Echinococcus multilocularis nmda type glutamate receptor 0.2988 0.4059 0.4058
Brugia malayi hypothetical protein 0.0028 0.0004 0.0004
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0292 0.0365 0.0538
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0014 0.0051
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0008 0.0006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0062 0.005 0.0049
Mycobacterium ulcerans O-methyltransferase 0.1772 0.2393 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0217 0.0262 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0027 0.0002 0.0002
Echinococcus multilocularis hyperpolarization activated cyclic 0.0187 0.0221 0.022
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0189 0.0224 0.0875
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.039 0.0499 0.0498
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0009 0.0219
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0187 0.0221 0.6049
Schistosoma mansoni ferritin light chain 0.0107 0.0112 0.011
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0639 0.084 0.1242
Echinococcus granulosus histone acetyltransferase MYST2 0.0119 0.0128 0.0127
Schistosoma mansoni retinoic acid receptor RXR 0.0033 0.001 0.0007
Brugia malayi O-methyltransferase family protein 0.0184 0.0217 0.0319
Loa Loa (eye worm) hypothetical protein 0.0054 0.0039 0.0056
Loa Loa (eye worm) hypothetical protein 0.0028 0.0004 0.0004
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.021 0.0253 0.099
Echinococcus multilocularis transient receptor potential cation channel 0.0187 0.0221 0.022
Loa Loa (eye worm) melatonin receptor type 1A 0.0027 0.0002 0.0002
Brugia malayi Tachykinin-like peptides receptor 99D 0.0027 0.0002 0.0002
Mycobacterium ulcerans methyltransferase 0.0184 0.0217 0.089
Echinococcus granulosus low density lipoprotein receptor ldl 0.0029 0.0005 0.0004
Echinococcus granulosus BTB:POZ domain containing protein KCTD16 0.0217 0.0262 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.003 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Echinococcus multilocularis carboxylesterase 5A 0.0322 0.0407 0.0406
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0018 0.0324
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0187 0.0221 0.0325
Brugia malayi Cytochrome P450 family protein 0.0082 0.0078 0.0114
Loa Loa (eye worm) glutaminase 0.0306 0.0384 0.0567
Giardia lamblia Kinase, CMGC MAPK 0.0106 0.011 0.125
Brugia malayi Dopamine receptor protein 1 0.0027 0.0002 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0217 0.0262 0.0259
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0004 0.0088
Mycobacterium tuberculosis Probable hydrolase 0.0292 0.0365 0.1433
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0029 0.0004 0.0123
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0099
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0107 0.0112 0.5072
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0033 0.001 0.0013
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0009 0.0146
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0248 0.0305 0.0304
Echinococcus multilocularis somatostatin receptor 0.0027 0.0002 0.0001
Echinococcus granulosus orexin receptor type 2 0.0027 0.0002 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Echinococcus granulosus g protein coupled receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.008 0.0075 0.0109
Echinococcus granulosus fmrfamide receptor 0.0027 0.0002 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Trypanosoma cruzi potassium voltage-gated channel 0.0217 0.0262 0.4772
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0033 0.001 0.0013
Schistosoma mansoni calcium-activated potassium channel 0.0407 0.0523 0.052
Echinococcus multilocularis g-protein coupled receptor 0.0027 0.0002 0.0001
Entamoeba histolytica heat shock transcription factor, putative 0.0114 0.0121 0.1377
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0027 0.0002 0.0001
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0212 0.0255 0.0254
Brugia malayi mbt repeat family protein 0.0104 0.0108 0.0158
Schistosoma mansoni DNA polymerase eta 0.0045 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0212 0.0255 0.0253
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0002 0.0001
Leishmania major hypothetical protein, conserved 0.01 0.0103 0.2798
Plasmodium falciparum importin beta, putative 0.0032 0.0009 0.0306
Loa Loa (eye worm) hypothetical protein 0.003 0.0006 0.0008
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0187 0.0221 0.022
Schistosoma mansoni tyrosine kinase 0.0149 0.017 0.0167
Echinococcus granulosus cpg binding protein 0.0234 0.0285 0.0284
Echinococcus multilocularis FTZ F1 alpha 0.0033 0.001 0.0009
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0027 0.0002 0.0001
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0029 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Mycobacterium tuberculosis Carboxylesterase LipT 0.0054 0.004 0.014
Leishmania major 4-coumarate:coa ligase-like protein 0.0054 0.0038 0.1037
Echinococcus multilocularis tyrosine kinase 0.0149 0.017 0.0168
Echinococcus granulosus cyclin dependent kinase 1 0.009 0.0088 0.0087
Brugia malayi Serotonin receptor 0.0027 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0054 0.0039 0.0143
Brugia malayi O-methyltransferase family protein 0.0184 0.0217 0.0319
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0054 0.0039 0.0136
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.003 0.08
Echinococcus granulosus importin subunit beta 1 0.0032 0.0009 0.0008
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0045 0.0027 0.0026
Onchocerca volvulus Arrow homolog 0.0029 0.0005 0.0011
Echinococcus multilocularis allatostatin A receptor 0.0027 0.0002 0.0001
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0441 0.0569 0.0568
Schistosoma mansoni hypothetical protein 0.0886 0.1179 0.1177
Mycobacterium tuberculosis Probable catechol-O-methyltransferase 0.1588 0.2141 0.8499
Plasmodium vivax kelch protein K13, putative 0.0217 0.0262 0.7168
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0147 0.0166 0.0165
Onchocerca volvulus 0.0172 0.0201 0.0738
Schistosoma mansoni mixed-lineage leukemia protein mll 0.004 0.002 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Trypanosoma brucei hypothetical protein, conserved 0.0292 0.0365 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Plasmodium falciparum protein kinase 5 0.009 0.0088 0.3339
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0012 0.0011
Entamoeba histolytica transcription factor BTF3, putative 0.0039 0.0018 0.0204
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0029 0.0005 0.0004
Brugia malayi Cation transporter family protein 0.0058 0.0044 0.0064
Brugia malayi Carboxylesterase family protein 0.0322 0.0407 0.06
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0002 0.0002
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0029 0.0004 0.0088
Loa Loa (eye worm) hypothetical protein 0.0184 0.0217 0.0319
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0257 0.0316 0.0315
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0033 0.001 0.0009
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0029 0.0005 0.0004
Loa Loa (eye worm) potassium channel tetramerisation domain containing 5 0.0217 0.0262 0.0386
Onchocerca volvulus Protein ultraspiracle homolog 0.0033 0.001 0.0028
Schistosoma mansoni hypothetical protein 0.0044 0.0025 0.0023
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0054 0.0039 0.0143
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0107 0.0112 0.0429
Echinococcus multilocularis 0.0054 0.0039 0.0037
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0187 0.0221 0.022
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0054 0.0039 0.0143
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0114 0.0122 0.012
Echinococcus granulosus mitogen activated protein kinase 0.0106 0.011 0.0109
Schistosoma mansoni transcription factor LCR-F1 0.0114 0.0122 0.0119
Schistosoma mansoni inositol transporter 0.0043 0.0024 0.0021
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Onchocerca volvulus 0.0184 0.0217 0.0797
Schistosoma mansoni hypothetical protein 0.0202 0.0242 0.024
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0009 0.0006
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0172 0.0201 0.0296
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0058 0.0044 0.0042
Loa Loa (eye worm) O-methyltransferase 0.0184 0.0217 0.0319
Brugia malayi voltage-dependent calcium channel 0.0187 0.0221 0.0325
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0002 0.0001
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0045 0.0027 0.0026
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0212 0.0255 0.6988
Trypanosoma brucei potassium voltage-gated channel, putative 0.0217 0.0262 0.7168
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0291 0.0364 0.0363
Trypanosoma cruzi PAB1-binding protein , putative 0.01 0.0103 0.1862
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.001 0.0009
Echinococcus granulosus Smad4 0.0034 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Leishmania major DNA polymerase eta, putative 0.0032 0.0009 0.0218
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0001 0.0004
Brugia malayi CUB domain containing protein 0.0029 0.0005 0.0006
Mycobacterium leprae Conserved hypothetical protein 0.0054 0.0039 0.0002
Plasmodium falciparum thioredoxin reductase 0.0029 0.0004 0.0123
Schistosoma mansoni transient receptor potential channel 0.0187 0.0221 0.0219
Mycobacterium ulcerans acyl-CoA synthetase 0.0054 0.0038 0.0143
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0038
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Echinococcus granulosus g protein coupled receptor 0.0027 0.0002 0.0001
Onchocerca volvulus 0.0035 0.0013 0.004
Brugia malayi K+ channel tetramerisation domain containing protein 0.0217 0.0262 0.0386
Echinococcus granulosus hypothetical protein 0.0187 0.0221 0.022
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0008 0.0007
Trypanosoma cruzi Thiopurine S-methyltransferase (TPMT), putative 0.0048 0.0031 0.0559
Brugia malayi Cytochrome P450 family protein 0.0054 0.0039 0.0055
Brugia malayi Receptor family ligand binding region containing protein 0.0149 0.017 0.0249
Echinococcus granulosus BC026374 protein S09 family 0.0054 0.004 0.0038
Trypanosoma cruzi cdc2-related kinase 3 0.009 0.0088 0.1598
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0289 0.0362 0.0533
Echinococcus granulosus GPCR family 2 0.0202 0.0242 0.0241
Schistosoma mansoni ATP-binding cassette transporter 0.0291 0.0364 0.0362
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0192 0.0229 0.0337
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0747 0.0988 1
Loa Loa (eye worm) glutathione reductase 0.0083 0.0079 0.0115
Brugia malayi jmjC domain containing protein 0.0058 0.0044 0.0064
Toxoplasma gondii NAC domain-containing protein 0.0039 0.0018 0.0318
Echinococcus multilocularis Protein lozenge 0.0117 0.0125 0.0124
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0107 0.0112 0.011
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0291 0.0364 0.0363
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0187 0.0221 0.0325
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0217 0.0262 0.0386
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.011 0.0108
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0033 0.001 0.0009
Schistosoma mansoni hypothetical protein 0.0344 0.0436 0.0434
Leishmania major hypothetical protein, conserved 0.0187 0.0221 0.6053
Echinococcus granulosus BTB:POZ domain containing protein 0.0217 0.0262 0.0261
Trypanosoma cruzi extracellular receptor, putative 0.0149 0.017 0.3088
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0149 0.017 0.0249
Echinococcus granulosus potassium voltage gated channel subfamily A 0.4957 0.6757 0.6756
Schistosoma mansoni transcription factor btf3 0.0039 0.0018 0.0016
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0013 0.0222
Schistosoma mansoni high-affinity choline transporter 0.0389 0.0498 0.0496
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0189 0.0224 0.0875
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0518 0.0515
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0217 0.0262 0.4772
Echinococcus multilocularis cyclin dependent kinase 0.009 0.0088 0.0087
Loa Loa (eye worm) RGC/RGC protein kinase 0.0149 0.017 0.0249
Brugia malayi metabotropic glutamate receptor type 2 0.0149 0.017 0.0249
Loa Loa (eye worm) hypothetical protein 0.4957 0.6757 1
Onchocerca volvulus 0.0292 0.0365 0.1346
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0002 0.0001
Trypanosoma brucei cdc2-related kinase 3 0.009 0.0088 0.2393
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0002 0.0001
Echinococcus multilocularis shaker cognate 0.0403 0.0518 0.0517
Brugia malayi Voltage-gated potassium channel, Shal-family (KCND, Kv4-like) alpha-subunit. C. elegans shl-1 ortholog 0.0217 0.0262 0.0386
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.004 0.002 0.0062
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0217 0.0262 0.0386
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Echinococcus multilocularis voltage gated potassium channel 0.0187 0.0221 0.022
Brugia malayi mbt repeat family protein 0.0104 0.0108 0.0158
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0106 0.011 0.1998
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Brugia malayi intermediate filament protein 0.0172 0.0201 0.0296
Loa Loa (eye worm) hypothetical protein 0.0322 0.0407 0.06
Loa Loa (eye worm) hypothetical protein 0.0217 0.0262 0.0386
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0292 0.0365 0.1433
Brugia malayi glutaminase DH11.1 0.0306 0.0384 0.0567
Schistosoma mansoni ferritin 0.0107 0.0112 0.011
Plasmodium falciparum basic transcription factor 3b, putative 0.0039 0.0018 0.0666
Brugia malayi Receptor family ligand binding region containing protein 0.0149 0.017 0.0249
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0291 0.0364 0.0363
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0043 0.0024 0.0023
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0027 0.0002 0.0001
Echinococcus granulosus basement membrane specific heparan sulfate 0.0029 0.0005 0.0004
Entamoeba histolytica heat shock transcription factor, putative 0.0114 0.0121 0.1377
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0119 0.0128 0.0127
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0004 0.0066
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus voltage gated potassium channel 0.0187 0.0221 0.022
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0029 0.0005 0.0004
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.004 0.002 0.0158
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0248 0.0305 0.0302
Leishmania major hypothetical protein, conserved 0.0048 0.0031 0.084
Echinococcus granulosus aryl hydrocarbon receptor 0.0028 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0104 0.0108 0.0158
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0054 0.0039 0.0136
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0054 0.0038 0.0143
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0062 0.0049 0.0183
Schistosoma mansoni cpg binding protein 0.0214 0.0258 0.0256
Onchocerca volvulus 0.0187 0.0221 0.0812
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Onchocerca volvulus 0.0043 0.0024 0.008
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0104 0.0108 0.0106
Schistosoma mansoni survival motor neuron protein 0.0315 0.0397 0.0395
Brugia malayi follicle stimulating hormone receptor 0.0027 0.0002 0.0002
Leishmania major cathepsin L-like protease 0.0066 0.0056 0.1513
Trypanosoma brucei btb/poz domain containing protein, putative 0.0217 0.0262 0.7168
Echinococcus multilocularis glutamate receptor NMDA 0.195 0.2636 0.2635
Echinococcus granulosus Polycystic kidney disease protein 0.0089 0.0087 0.0086
Echinococcus granulosus lipoxygenase domain containing protein 0.0089 0.0087 0.0086
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0415 0.0534 0.0533
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.003 0.08
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.0049 0.0183
Loa Loa (eye worm) beta-lactamase 0.0292 0.0365 0.0538
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0187 0.0221 0.0219
Loa Loa (eye worm) hypothetical protein 0.0045 0.0026 0.0037
Schistosoma mansoni cpg binding protein 0.0234 0.0285 0.0283
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0054 0.0039 0.0136
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0415 0.0534 0.0533
Echinococcus granulosus voltage gated potassium channel 0.0403 0.0518 0.0517
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0008 0.001
Toxoplasma gondii aldehyde dehydrogenase 0.0137 0.0153 0.2782
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0088 0.0327
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.0054 0.0038 0.1037
Schistosoma mansoni myelin transcription factor 1 myt1 0.0119 0.0128 0.0125
Onchocerca volvulus 0.1992 0.2694 1
Schistosoma mansoni o-methyltransferase 0.0184 0.0217 0.0215
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0009 0.0221
Echinococcus granulosus dna polymerase eta 0.0045 0.0027 0.0026
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0088 0.0327
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0007 0.0026
Onchocerca volvulus 0.0217 0.0262 0.0965
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0054 0.004 0.0038
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0187 0.0221 0.022
Trypanosoma cruzi ISWI complex protein 0.0063 0.0051 0.0914
Schistosoma mansoni polycystin 1-related 0.0089 0.0087 0.0085
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis acetylcholinesterase 0.0322 0.0407 0.0406
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Mycobacterium ulcerans aldehyde dehydrogenase 0.0137 0.0153 0.0621
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0002 0.0001
Schistosoma mansoni glutamate receptor kainate 0.0291 0.0364 0.0362
Echinococcus multilocularis short transient receptor potential channel 6 0.0187 0.0221 0.022
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.4957 0.6757 1
Leishmania major hypothetical protein, conserved 0.0217 0.0262 0.7171
Loa Loa (eye worm) voltage-dependent calcium channel 0.0187 0.0221 0.0325
Loa Loa (eye worm) carboxylesterase 0.0054 0.004 0.0057
Echinococcus multilocularis musashi 0.0172 0.0201 0.02
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0009 0.0008
Plasmodium falciparum thioredoxin reductase 0.0083 0.0079 0.2976
Echinococcus multilocularis neuroligin 0.0054 0.004 0.0038
Onchocerca volvulus 0.0217 0.0262 0.0963
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0002 0.0001
Giardia lamblia DNA repair protein RAD52 0.0353 0.0448 0.5136
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0027 0.0002 0.0002
Brugia malayi ImpB/MucB/SamB family protein 0.0045 0.0027 0.0039
Trypanosoma cruzi cytochrome P450, putative 0.0082 0.0078 0.1413
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus sodium channel protein 0.0187 0.0221 0.022
Onchocerca volvulus 0.0149 0.017 0.0621
Loa Loa (eye worm) Smad1 0.0034 0.0012 0.0016
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0248 0.0305 0.0449
Brugia malayi O-methyltransferase 0.0184 0.0217 0.0319
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.001 0.0013
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0008 0.0188
Schistosoma mansoni aldehyde dehydrogenase 0.0137 0.0153 0.015
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0292 0.0365 0.1508
Echinococcus granulosus peptide allatostatin:somatostatin 0.0027 0.0002 0.0001
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.003 0.0334
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.001 0.0013
Loa Loa (eye worm) bromodomain containing protein 0.0072 0.0064 0.0093
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Echinococcus multilocularis serotonin receptor 0.0027 0.0002 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Echinococcus multilocularis lamin 0.0172 0.0201 0.02
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0054 0.0039 0.0143
Schistosoma mansoni ryanodine receptor related 0.0187 0.0221 0.0219
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0187 0.0221 0.0325
Brugia malayi AMP-binding enzyme family protein 0.0054 0.0038 0.0055
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0054 0.0039 0.0691
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0137 0.0153 0.0152
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0202 0.0242 0.0241
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0054 0.0039 0.0136
Brugia malayi Low-density lipoprotein receptor-related protein, putative 0.0029 0.0005 0.0006
Loa Loa (eye worm) voltage-gated calcium channel 0.0187 0.0221 0.0325
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0054 0.0039 0.0143
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0054 0.0039 0.0136
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0292 0.0365 0.0538
Echinococcus granulosus cyclin dependent kinase 5 0.009 0.0088 0.0087
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0403 0.0518 0.0517
Echinococcus granulosus two pore calcium channel protein 1 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Schistosoma mansoni protein kinase 0.0149 0.017 0.0167
Echinococcus multilocularis ferritin 0.0107 0.0112 0.0111
Schistosoma mansoni hypothetical protein 0.0428 0.0551 0.0549
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0002 0.0002
Trypanosoma cruzi cdc2-related kinase 1 0.009 0.0088 0.1598
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Conserved protein 0.0292 0.0365 0.1433
Echinococcus multilocularis muscleblind protein 1 0.0951 0.1267 0.1266
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0033 0.001 0.0028
Echinococcus multilocularis glutamate receptor 2 0.0149 0.017 0.0168
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0217 0.0262 0.4772
Brugia malayi cytoplasmic intermediate filament protein 0.0092 0.0091 0.0134
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Mycobacterium ulcerans aldehyde dehydrogenase 0.0137 0.0153 0.0621
Echinococcus multilocularis neuropeptide FF receptor 2 0.0027 0.0002 0.0001
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0241 0.0295 0.0294
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus hyperpolarization activated cyclic 0.0187 0.0221 0.022
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0217 0.0262 0.4772
Schistosoma mansoni rab6-interacting 0.0089 0.0087 0.0085
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0187 0.0221 0.022
Echinococcus granulosus Low density lipoprotein receptor class A cysteine rich 0.0029 0.0005 0.0004
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0054 0.0039 0.0143
Trichomonas vaginalis chromobox protein, putative 0.008 0.0075 0.0277
Echinococcus granulosus FTZ F1 alpha 0.0033 0.001 0.0009
Schistosoma mansoni metabotropic glutamate receptor 0.0149 0.017 0.0167
Echinococcus multilocularis chromobox protein 1 0.008 0.0075 0.0073
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0029 0.0005 0.0004
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0019 0.0069
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.011 0.0408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0004 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0062
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Schistosoma mansoni cellular tumor antigen P53 0.0217 0.0262 0.026
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus sodium:myo inositol cotransporter 0.0043 0.0024 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0054 0.0039 0.0136
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0033 0.001 0.0007
Schistosoma mansoni hypothetical protein 0.0084 0.0081 0.0078
Echinococcus granulosus calcium activated potassium channel 0.0189 0.0224 0.0222
Echinococcus granulosus tyrosine kinase 0.0149 0.017 0.0168
Mycobacterium ulcerans acyl-CoA synthetase 0.0054 0.0038 0.0143
Schistosoma mansoni sex comb on midleg homolog 0.0104 0.0108 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0018 0.0069
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0027 0.0002 0.0002
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0106 0.011 0.0161
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.021 0.0253 0.099
Echinococcus granulosus basement membrane specific heparan sulfate 0.0029 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Schistosoma mansoni voltage-gated potassium channel 0.4957 0.6757 0.6756
Entamoeba histolytica hypothetical protein 0.0039 0.0018 0.0204
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0062
Chlamydia trachomatis glutamine binding protein 0.0747 0.0988 1
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0054 0.004 0.0037
Brugia malayi photoreceptor-specific nuclear receptor 0.0033 0.001 0.0013
Schistosoma mansoni o-methyltransferase 0.0184 0.0217 0.0215
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0043 0.0024 0.0023
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1751 0.2364 0.3497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.003 0.0111
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0054 0.004 0.0037
Loa Loa (eye worm) CHromoDomain protein family member 0.0033 0.001 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0004 0.0014
Plasmodium falciparum zinc finger protein, putative 0.0033 0.001 0.0349
Schistosoma mansoni voltage-dependent calcium channel 0.0187 0.0221 0.0219
Echinococcus multilocularis snurportin 1 0.0344 0.0436 0.0435
Onchocerca volvulus 0.0268 0.0332 0.1226
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0212 0.0255 0.0376
Schistosoma mansoni hypothetical protein 0.0202 0.0242 0.024
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0344 0.0436 0.0644
Leishmania major hypothetical protein, conserved 0.0063 0.0051 0.1374
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0054 0.0039 0.0143
Trypanosoma brucei Thiopurine S-methyltransferase (TPMT), putative 0.0048 0.0031 0.0831
Brugia malayi SET domain containing protein 0.0027 0.0002 0.0001
Echinococcus multilocularis peregrin 0.0041 0.0021 0.002
Brugia malayi chromobox protein homolog 3 0.0045 0.0026 0.0037
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0029 0.0004 0.0088
Mycobacterium leprae putative cytochrome p450 0.0054 0.0039 0.0002
Plasmodium falciparum kelch protein K13 0.0217 0.0262 1
Brugia malayi G protein-coupled receptor 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Conserved protein 0.0292 0.0365 0.1433
Echinococcus granulosus transient receptor potential cation channel 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0106 0.011 0.0161
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0106 0.011 0.1253
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis potassium voltage gated channel protein 0.0187 0.0221 0.022
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0187 0.0221 0.0219
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0187 0.0221 0.022
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0187 0.0221 0.0219
Plasmodium falciparum acyl-CoA synthetase 0.004 0.002 0.072
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.0049 0.0183
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0054 0.0039 0.0136
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.009 0.0088 0.0087
Schistosoma mansoni vesicular amine transporter 0.0403 0.0518 0.0515
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.011 0.0408
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0212 0.0255 0.4652
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0017 0.005
Mycobacterium tuberculosis Probable lipase LipE 0.0292 0.0365 0.1433
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0002 0.0001
Schistosoma mansoni potassium channel tetramerization domain-containing 0.0217 0.0262 0.0259
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Schistosoma mansoni hypothetical protein 0.0089 0.0087 0.0085
Schistosoma mansoni edp1-related 0.0217 0.0262 0.0259
Plasmodium vivax importin-beta 2, putative 0.0032 0.0009 0.0219
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0066
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0463 0.0599 0.0597
Brugia malayi hypothetical protein 0.0123 0.0133 0.0196
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0075 0.0068 0.0067
Echinococcus multilocularis tar DNA binding protein 0.0471 0.061 0.0609
Plasmodium falciparum ataxin-2 like protein, putative 0.01 0.0103 0.3892
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Echinococcus granulosus metabotropic glutamate receptor 5 0.0149 0.017 0.0168
Toxoplasma gondii K+ channel tetramerisation domain-containing protein 0.0217 0.0262 0.4781
Echinococcus granulosus polycomb protein SCMH1 0.0104 0.0108 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0003 0.0012
Loa Loa (eye worm) carboxylesterase 0.0322 0.0407 0.06
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0012 0.0016
Schistosoma mansoni hypothetical protein 0.0044 0.0025 0.0023
Schistosoma mansoni voltage-gated cation channel 0.0187 0.0221 0.0219
Onchocerca volvulus 0.0054 0.004 0.0139
Schistosoma mansoni bromodomain containing protein 0.003 0.0006 0.0003
Mycobacterium ulcerans fatty-acid-CoA ligase 0.004 0.002 0.0065
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0025 0.0024
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0083 0.0079 0.0115
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.003 0.0334
Trichomonas vaginalis D-aminoacylase, putative 0.0292 0.0365 0.1353
Onchocerca volvulus Huntingtin homolog 0.0123 0.0133 0.0487
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0017 0.0436
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.003 0.0532
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0187 0.0221 0.0812
Echinococcus multilocularis transient receptor potential cation channel 0.0187 0.0221 0.022
Echinococcus granulosus potassium voltage gated channel protein 0.4957 0.6757 0.6756
Loa Loa (eye worm) runx1 0.0117 0.0125 0.0183
Schistosoma mansoni rab6-interacting 0.0089 0.0087 0.0085
Loa Loa (eye worm) hypothetical protein 0.004 0.002 0.0028
Loa Loa (eye worm) hypothetical protein 0.0114 0.0121 0.0177
Toxoplasma gondii hypothetical protein 0.0187 0.0221 0.4034
Echinococcus multilocularis dro:myosuppressin receptor 0.0027 0.0002 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0187 0.0221 0.0219
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0002 0.0001
Echinococcus granulosus glutamate receptor NMDA 0.195 0.2636 0.2635
Brugia malayi ORL1-like opioid receptor 0.0027 0.0002 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0518 0.0515
Mycobacterium ulcerans glutaminase 0.0306 0.0384 0.1591
Echinococcus multilocularis muscleblind protein 0.0951 0.1267 0.1266
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0149 0.017 0.0621
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0248 0.0305 0.0304
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0033 0.001 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0292 0.0365 0.6654
Mycobacterium ulcerans esterase/lipase LipP 0.0292 0.0365 0.1508
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0518 0.0515
Trypanosoma brucei Thiopurine S-methyltransferase (TPMT), putative 0.0048 0.0031 0.0831
Brugia malayi Carboxylesterase family protein 0.0054 0.004 0.0057
Brugia malayi PHD-finger family protein 0.0114 0.0121 0.0178
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0017 0.029
Schistosoma mansoni hypothetical protein 0.0202 0.0242 0.024
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Onchocerca volvulus 0.0029 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Onchocerca volvulus 0.0214 0.0258 0.095
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0189 0.0224 0.0875
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0029 0.0005 0.0003
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.001 0.0007
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.003 0.0029
Brugia malayi HSF-type DNA-binding domain containing protein 0.0114 0.0121 0.0177
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0187 0.0221 0.0219
Echinococcus granulosus sodium:glucose cotransporter 2 0.0043 0.0024 0.0023
Brugia malayi SET domain containing protein 0.0034 0.0011 0.0015
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0054 0.0039 0.1039
Trichomonas vaginalis glutathione reductase, putative 0.0029 0.0004 0.0016
Trypanosoma cruzi trypanothione reductase, putative 0.0083 0.0079 0.1425
Giardia lamblia Fructose-bisphosphate aldolase 0.0662 0.0871 1
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0002 0.0001
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0217 0.0262 0.4772
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0027 0.0002 0.0001
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0001 0.0007
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0002 0.0001
Echinococcus granulosus potassium voltage gated channel protein 0.0403 0.0518 0.0517
Schistosoma mansoni methyl-cpg binding protein mbd 0.007 0.0061 0.0058
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0292 0.0365 0.0362
Brugia malayi Cytochrome P450 family protein 0.0082 0.0078 0.0114
Echinococcus multilocularis receptor type guanylyl cyclase 0.0149 0.017 0.0168
Echinococcus multilocularis chromobox protein 1 0.008 0.0075 0.0073
Schistosoma mansoni zinc finger protein 0.0063 0.0051 0.0048
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Leishmania major hypothetical protein, unknown function 0.0187 0.0221 0.6053
Echinococcus multilocularis tumor protein p63 0.1482 0.1995 0.1995
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.003 0.079
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Leishmania major cytochrome p450-like protein 0.0054 0.0039 0.1039
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0088 0.0327
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0403 0.0518 0.0765
Loa Loa (eye worm) ICD-1 protein 0.0039 0.0018 0.0026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0292 0.0365 0.0362
Toxoplasma gondii thioredoxin reductase 0.0083 0.0079 0.1423
Loa Loa (eye worm) CYP4Cod1 0.0082 0.0078 0.0114
Entamoeba histolytica hypothetical protein 0.0114 0.0122 0.1388
Brugia malayi hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis smad 0.0034 0.0012 0.0011
Mycobacterium tuberculosis Probable esterase LipL 0.0292 0.0365 0.1433
Onchocerca volvulus 0.0029 0.0005 0.0011
Onchocerca volvulus 0.0104 0.0108 0.0392
Echinococcus multilocularis nmda type glutamate receptor 0.2099 0.2841 0.284
Echinococcus granulosus mixed lineage leukemia protein mll 0.0062 0.005 0.0049
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0029 0.0004 0.0005
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0009 0.0147
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0106 0.011 0.3002
Brugia malayi GH02984p 0.0389 0.0498 0.0736
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0187 0.0221 0.022
Onchocerca volvulus 0.0034 0.0011 0.0034
Mycobacterium ulcerans bacterioferritin BfrB 0.0107 0.0112 0.0451
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) transcription factor SMAD2 0.05 0.065 0.0961
Loa Loa (eye worm) hypothetical protein 0.0058 0.0044 0.0064
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0441 0.0569 0.0568
Loa Loa (eye worm) hypothetical protein 0.0292 0.0365 0.0538
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0149 0.017 0.0168
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0029 0.0005 0.0003
Plasmodium vivax acyl-CoA synthetase, putative 0.004 0.002 0.0516
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Echinococcus granulosus hyperpolarization activated cyclic 0.0187 0.0221 0.022
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.0027 0.0026
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0217 0.0262 0.0386
Brugia malayi O-methyltransferase family protein 0.0184 0.0217 0.0319
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0662 0.0871 1
Echinococcus granulosus Niemann Pick C1 protein 0.0151 0.0172 0.0171
Echinococcus multilocularis protein dispatched 1 0.0052 0.0036 0.0035
Brugia malayi Niemann-Pick C1 protein precursor 0.0106 0.011 0.0161
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0106 0.011 0.1998
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Echinococcus granulosus snurportin 1 0.0344 0.0436 0.0435
Echinococcus multilocularis serotonin receptor 0.0027 0.0002 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0004 0.0088
Brugia malayi G protein-coupled receptor F59B2.13 0.0027 0.0002 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0033 0.001 0.0009
Leishmania major trypanothione reductase 0.0083 0.0079 0.2142
Mycobacterium ulcerans methyltransferase 0.0048 0.0031 0.0113
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0033 0.001 0.0009
Schistosoma mansoni hypothetical protein 0.0437 0.0563 0.0561
Brugia malayi isocitrate dehydrogenase 0.0032 0.0009 0.0011
Brugia malayi K+ channel tetramerisation domain containing protein 0.0217 0.0262 0.0386
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0202 0.0242 0.0241
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0187 0.0221 0.022
Schistosoma mansoni glutamate receptor AMPA 0.0291 0.0364 0.0362
Echinococcus granulosus nmda type glutamate receptor 0.2988 0.4059 0.4058
Echinococcus granulosus short transient receptor potential channel 6 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0088 0.0086 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Onchocerca volvulus 0.0089 0.0087 0.0316
Loa Loa (eye worm) hypothetical protein 0.0089 0.0087 0.0128
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Toxoplasma gondii LsmAD domain-containing protein 0.01 0.0103 0.1861
Mycobacterium ulcerans acyl-CoA synthetase 0.0054 0.0038 0.0143
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0189 0.0224 0.0875
Loa Loa (eye worm) voltage-gated potassium channel 0.0403 0.0518 0.0765
Schistosoma mansoni sex comb on midleg homolog 0.0104 0.0108 0.0106
Echinococcus granulosus nmda type glutamate receptor 0.2099 0.2841 0.284
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0029 0.0004 0.0088
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0002 0.0001
Echinococcus granulosus small conductance calcium activated potassium 0.0428 0.0551 0.055
Echinococcus granulosus alpha 1A adrenergic receptor 0.0027 0.0002 0.0001
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.003 0.079
Echinococcus granulosus TRP transient receptor potential channel 0.0187 0.0221 0.022
Brugia malayi Pre-SET motif family protein 0.0255 0.0314 0.0464
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0002 0.0001
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0187 0.0221 0.0219
Trypanosoma brucei cdc2-related kinase 1 0.009 0.0088 0.2393
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.001 0.0009
Echinococcus granulosus smad 0.0034 0.0012 0.0011
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0747 0.0988 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0027 0.0002 0.0001
Trypanosoma cruzi Thiopurine S-methyltransferase (TPMT), putative 0.0048 0.0031 0.0559
Loa Loa (eye worm) hypothetical protein 0.0292 0.0365 0.0538
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0441 0.0569 0.0568
Schistosoma mansoni hypothetical protein 0.2636 0.3576 0.3575
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0123 0.0133 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0003 0.0012
Loa Loa (eye worm) mbt repeat family protein 0.0104 0.0108 0.0158
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.0027 0.0038
Loa Loa (eye worm) hypothetical protein 0.0054 0.0039 0.0055
Echinococcus multilocularis beta LACTamase domain containing family member 0.0292 0.0365 0.0363
Brugia malayi RNA binding protein 0.0471 0.061 0.0902
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0062
Brugia malayi hypothetical protein 0.0089 0.0087 0.0128
Schistosoma mansoni ferritin 0.0107 0.0112 0.011
Echinococcus multilocularis thioredoxin glutathione reductase 0.0084 0.008 0.0079
Schistosoma mansoni two-pore calcium channel 0.0187 0.0221 0.0219
Echinococcus multilocularis BC026374 protein (S09 family) 0.0054 0.004 0.0038
Entamoeba histolytica hypothetical protein 0.0114 0.0122 0.1388
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0187 0.0221 0.4028
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0033 0.001 0.0013
Echinococcus granulosus voltage dependent calcium channel 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0032 0.0009 0.0012
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.003 0.0532
Trypanosoma cruzi hypothetical protein, conserved 0.0292 0.0365 0.6654
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0353 0.0448 0.5138
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.003 0.0042
Echinococcus multilocularis orexin receptor type 2 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.008 0.0075 0.0109
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0027 0.0002 0.0002
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0187 0.0221 0.6049
Echinococcus granulosus dro:myosuppressin receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0187 0.0221 0.0219
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Echinococcus multilocularis short transient receptor potential channel 6 0.0187 0.0221 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Brugia malayi basement membrane proteoglycan precursor 0.0029 0.0005 0.0006
Onchocerca volvulus 0.0054 0.004 0.0139
Echinococcus granulosus 5'partial|Low density lipoprotein receptor class A cysteine rich 0.0029 0.0005 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0033 0.001 0.0013
Schistosoma mansoni smad 0.0034 0.0012 0.0009
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Echinococcus granulosus transient receptor potential cation channel 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Brugia malayi Guanylyl cyclase protein 23 0.0149 0.017 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.002 0.0076
Echinococcus granulosus atrial natriuretic peptide receptor 0.0149 0.017 0.0168
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Schistosoma mansoni lamin 0.0172 0.0201 0.0199
Brugia malayi Sodium:solute symporter family protein 0.0043 0.0024 0.0033
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0043 0.0024 0.0023
Echinococcus granulosus methyl CpG binding domain protein 2 0.007 0.0061 0.0059
Leishmania major DNA polymerase eta, putative 0.0045 0.0027 0.0726
Entamoeba histolytica cell division protein kinase 2, putative 0.009 0.0088 0.1003
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0187 0.0221 0.0219
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.009 0.0088 0.2402
Schistosoma mansoni importin beta-1 0.0032 0.0009 0.0007
Plasmodium falciparum ataxin-2 like protein, putative 0.01 0.0103 0.3892
Echinococcus granulosus carboxylesterase 5A 0.0322 0.0407 0.0406
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0025 0.0024
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0033 0.001 0.0008
Schistosoma mansoni cpg binding protein 0.0234 0.0285 0.0283
Brugia malayi neuropeptide F receptor 0.0027 0.0002 0.0002
Schistosoma mansoni lipoxygenase 0.0229 0.0279 0.0277
Entamoeba histolytica acyl-CoA synthetase, putative 0.0054 0.0038 0.0433
Mycobacterium tuberculosis Probable methyltransferase 0.0184 0.0217 0.0846
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0026 0.0098
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0403 0.0518 0.0517
Echinococcus granulosus Niemann Pick C1 protein 0.0106 0.011 0.0109
Echinococcus granulosus lamin 0.0172 0.0201 0.02
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0187 0.0221 0.022
Entamoeba histolytica acyl-CoA synthetase, putative 0.0054 0.0038 0.0433
Brugia malayi enteropeptidase precursor 0.0029 0.0005 0.0006
Brugia malayi MH2 domain containing protein 0.0034 0.0012 0.0016
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0054 0.0039 0.0136
Loa Loa (eye worm) acetylcholinesterase 1 0.0322 0.0407 0.06
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0107 0.0112 0.0429
Brugia malayi steroid hormone receptor 0.0033 0.001 0.0013
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.021 0.0253 0.5817
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.001 0.0009
Plasmodium vivax protein kinase Crk2 0.009 0.0088 0.2393
Brugia malayi Calcitonin receptor-like protein seb-1 0.0639 0.084 0.1242
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0187 0.0221 0.022
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus chromobox protein 1 0.008 0.0075 0.0073
Brugia malayi Protein kinase domain containing protein 0.009 0.0088 0.0129
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Echinococcus multilocularis histone acetyltransferase MYST2 0.0119 0.0128 0.0127
Treponema pallidum fructose-bisphosphate aldolase 0.0662 0.0871 0.8814
Schistosoma mansoni o-methyltransferase 0.0184 0.0217 0.0215
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0082 0.0078 0.0308
Loa Loa (eye worm) hypothetical protein 0.0929 0.1238 0.1831
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0518 0.0515
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0054 0.0039 0.0143
Brugia malayi CHE-14 protein 0.0045 0.0027 0.0038
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0066
Mycobacterium tuberculosis Conserved protein 0.0048 0.0031 0.0107
Brugia malayi Calcium binding EGF domain containing protein 0.0029 0.0005 0.0006
Brugia malayi sulfakinin receptor protein 0.0027 0.0002 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus potassium voltage gated channel protein 0.0403 0.0518 0.0517
Leishmania major hypothetical protein, conserved 0.0217 0.0262 0.7171
Wolbachia endosymbiont of Brugia malayi O-methyltransferase 0.0184 0.0217 1
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0002 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0033 0.001 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0471 0.061 0.0608
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0212 0.0255 0.0254
Schistosoma mansoni glutamate receptor kainate 0.0291 0.0364 0.0362
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0029 0.0005 0.0004
Brugia malayi MH1 domain containing protein 0.0034 0.0012 0.0016
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.004 0.002 0.0028
Entamoeba histolytica heat shock transcription factor, putative 0.0114 0.0121 0.1377
Brugia malayi RNA recognition motif domain containing protein 0.0471 0.061 0.0902
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0033 0.001 0.0013
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0119 0.0128 0.0127
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.0049 0.0183
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0054 0.0039 0.0691
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0062
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0029 0.0005 0.0004
Echinococcus granulosus transcription factor btf3 0.0039 0.0018 0.0017
Echinococcus granulosus mitogen activated protein kinase 3 0.0106 0.011 0.0109
Leishmania major 4-coumarate:coa ligase-like protein 0.0054 0.0038 0.1037
Echinococcus multilocularis potassium large conductance calcium activated 0.0187 0.0221 0.022
Brugia malayi hypothetical protein 0.0929 0.1238 0.1831
Onchocerca volvulus 0.0029 0.0005 0.0011
Brugia malayi F/Y-rich N-terminus family protein 0.0093 0.0092 0.0134
Schistosoma mansoni ferritin light chain 0.0107 0.0112 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0018 0.0069
Schistosoma mansoni jumonji domain containing protein 0.0082 0.0077 0.0075
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0054 0.0039 0.0136
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.001 0.0009
Trypanosoma brucei trypanothione reductase 0.0083 0.0079 0.2133
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0149 0.017 0.0168
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0054 0.0078
Brugia malayi K+ channel tetramerisation domain containing protein 0.0217 0.0262 0.0386
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0255 0.0314 0.0312
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0268 0.0332 0.033
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0033 0.001 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0054 0.0039 0.0136
Loa Loa (eye worm) hypothetical protein 0.0054 0.0038 0.0055
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0202 0.0242 0.0241
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0187 0.0221 0.0219
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0031 0.0115
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0137 0.0153 0.0152
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0028 0.0004 0.0004
Schistosoma mansoni 60S ribosomal protein L21 0.0187 0.0221 0.0219
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Echinococcus granulosus neuropeptide receptor A26 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) calcium channel 0.0187 0.0221 0.0325
Echinococcus multilocularis aryl hydrocarbon receptor 0.0028 0.0004 0.0003
Brugia malayi Melatonin receptor type 1A 0.0027 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0114 0.0121 0.044
Loa Loa (eye worm) hypothetical protein 0.0167 0.0193 0.0285
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0017 0.005
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0029 0.0004 0.0059
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0187 0.0221 0.022
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0029 0.0004 0.0003
Brugia malayi nuclear receptor NHR-88 0.0033 0.001 0.0013
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0004 0.0066
Leishmania major cytochrome p450-like protein 0.0082 0.0078 0.2123
Trichomonas vaginalis chromobox protein, putative 0.008 0.0075 0.0277
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.0027 0.0026
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.009 0.0088 0.2402
Loa Loa (eye worm) hypothetical protein 0.0325 0.041 0.0605
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0002 0.0001
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0403 0.0518 0.0765
Mycobacterium leprae PROBABLE METHYLTRANSFERASE 0.0184 0.0217 0.4831
Loa Loa (eye worm) hypothetical protein 0.0929 0.1238 0.1831
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0291 0.0364 0.0363
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0403 0.0518 0.0517
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Echinococcus granulosus glutamate receptor 2 0.0441 0.0569 0.0568
Brugia malayi RE15519p 0.0027 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0026 0.0098
Giardia lamblia Kinase, CMGC CDK 0.009 0.0088 0.0999
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Brugia malayi RNA, U transporter 1 0.0092 0.0091 0.0132
Loa Loa (eye worm) CXXC zinc finger family protein 0.0214 0.0258 0.038
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0018 0.0324
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0002 0.0001
Entamoeba histolytica cell division protein kinase 2, putative 0.009 0.0088 0.1003
Echinococcus multilocularis Smad4 0.0034 0.0012 0.0011
Onchocerca volvulus 0.0217 0.0262 0.0963
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0202 0.0242 0.0356
Echinococcus granulosus thioredoxin glutathione reductase 0.0084 0.008 0.0079
Schistosoma mansoni nuclear hormone receptor 0.0033 0.001 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.0049 0.0183
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0033 0.001 0.0007
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0187 0.0221 0.0325
Plasmodium falciparum glutathione reductase 0.0083 0.0079 0.2976
Echinococcus multilocularis voltage dependent calcium channel 0.0187 0.0221 0.022
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0054 0.0039 0.103
Giardia lamblia PHD finger protein 15 0.0031 0.0008 0.0078
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0322 0.0407 0.0405
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0033 0.001 0.0013
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0325 0.041 0.0408
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0292 0.0365 0.0538
Plasmodium vivax SET domain protein, putative 0.0255 0.0314 0.8623
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0058 0.0044 0.0064
Schistosoma mansoni transient receptor potential channel 0.0187 0.0221 0.0219
Echinococcus granulosus transient receptor potential gamma protein 0.0187 0.0221 0.022
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0202 0.0242 0.0241
Brugia malayi Cyclic-nucleotide gated cation channel 0.0187 0.0221 0.0325
Brugia malayi hypothetical protein 0.0089 0.0087 0.0128
Echinococcus granulosus voltage dependent calcium channel 0.0187 0.0221 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Plasmodium vivax basic transcription factor 3b, putative 0.0039 0.0018 0.0477
Schistosoma mansoni apoferritin-2 0.0107 0.0112 0.011
Brugia malayi CHD4 protein 0.0033 0.001 0.0014
Echinococcus multilocularis potassium voltage gated channel protein 0.0403 0.0518 0.0517
Toxoplasma gondii transporter, cation channel family protein 0.0187 0.0221 0.4034
Echinococcus multilocularis para nitrobenzyl esterase 0.0054 0.004 0.0038
Brugia malayi MAP kinase sur-1 0.0106 0.011 0.0161
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0029 0.0004 0.0099
Echinococcus multilocularis ecdysone induced protein 78C 0.0033 0.001 0.0009
Schistosoma mansoni lipoxygenase 0.039 0.0499 0.0497
Echinococcus granulosus potassium voltage gated channel protein 0.0187 0.0221 0.022
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0103 0.0106 0.0105
Brugia malayi jmjC domain containing protein 0.0103 0.0106 0.0155
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0292 0.0365 0.1433
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0187 0.0221 0.022
Echinococcus granulosus voltage gated hydrogen channel 1 0.0187 0.0221 0.022
Echinococcus granulosus geminin 0.0886 0.1179 0.1178
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0441 0.0569 0.0568
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0217 0.0262 0.0386
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0147 0.0166 0.0165
Echinococcus granulosus shaker cognate 0.0403 0.0518 0.0517
Echinococcus granulosus histone lysine methyltransferase setb 0.0325 0.041 0.0409
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0187 0.0221 0.022
Echinococcus granulosus transcription factor Dp 1 0.0123 0.0133 0.0132
Echinococcus granulosus potassium voltage gated channel protein 0.0187 0.0221 0.022
Echinococcus granulosus acetylcholinesterase 0.0322 0.0407 0.0406
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0027 0.0002 0.0002
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0054 0.004 0.014
Echinococcus granulosus neuropeptide receptor 0.0027 0.0002 0.0001
Brugia malayi Intermediate filament tail domain containing protein 0.0172 0.0201 0.0296
Echinococcus granulosus ferritin 0.0107 0.0112 0.0111
Echinococcus granulosus lamin dm0 0.0172 0.0201 0.02
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0137 0.0153 0.4177
Echinococcus granulosus glutamate receptor 2 0.0149 0.017 0.0168
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0054 0.004 0.0038
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0187 0.0221 0.0219
Loa Loa (eye worm) cytochrome P450 family protein 0.0082 0.0078 0.0114
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0088 0.0086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0054 0.0039 0.0143
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus high affinity choline transporter 1 0.0389 0.0498 0.0497
Leishmania major hypothetical protein, conserved 0.0292 0.0365 1
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0054 0.0039 0.0143
Mycobacterium tuberculosis Conserved protein 0.0292 0.0365 0.1433
Brugia malayi hypothetical protein 0.0149 0.017 0.0249
Trypanosoma cruzi cdc2-related kinase 1 0.009 0.0088 0.1598
Echinococcus granulosus hypothetical protein 0.0027 0.0002 0.0001
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0001 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0104 0.0108 0.0392
Schistosoma mansoni hypothetical protein 0.0187 0.0221 0.0219
Trypanosoma brucei protein kinase, putative 0.0106 0.011 0.2995
Schistosoma mansoni loxhd1 0.0089 0.0087 0.0085
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Plasmodium vivax multidomain scavenger receptor, putative 0.0089 0.0087 0.2372
Schistosoma mansoni voltage-gated potassium channel 0.4957 0.6757 0.6756
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.009 0.0088 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0088 0.0086
Schistosoma mansoni acetylcholinesterase 0.0054 0.004 0.0037
Echinococcus multilocularis small conductance calcium activated potassium 0.0428 0.0551 0.055
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0187 0.0221 0.4028
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0217 0.0262 0.4772
Brugia malayi Bromodomain containing protein 0.0041 0.0021 0.003
Loa Loa (eye worm) hypothetical protein 0.004 0.002 0.0028
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0009 0.0008
Echinococcus multilocularis transcription factor btf3 0.0039 0.0018 0.0017
Echinococcus granulosus para nitrobenzyl esterase 0.0054 0.004 0.0038
Trichomonas vaginalis set domain proteins, putative 0.1992 0.2694 1
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0187 0.0221 0.022
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0033 0.001 0.0013
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0033 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Brugia malayi beta-lactamase 0.0292 0.0365 0.0538
Loa Loa (eye worm) cytochrome P450 family protein 0.0178 0.0209 0.0307
Brugia malayi Carboxylesterase family protein 0.0054 0.004 0.0057
Loa Loa (eye worm) intermediate filament protein 0.0172 0.0201 0.0296
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0009 0.0008
Onchocerca volvulus 0.0028 0.0004 0.0006
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0187 0.0221 0.022
Echinococcus multilocularis sodium channel protein 0.0187 0.0221 0.022
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0187 0.0221 0.022
Brugia malayi hypothetical protein 0.0065 0.0054 0.0078
Echinococcus multilocularis thyroid hormone receptor alpha 0.0033 0.001 0.0009
Echinococcus multilocularis SAM and MBT domain containing protein 0.0104 0.0108 0.0107
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0212 0.0255 0.0376
Onchocerca volvulus Huntingtin homolog 0.0123 0.0133 0.0487
Trypanosoma cruzi cytochrome P450, putative 0.0082 0.0078 0.1413
Loa Loa (eye worm) hypothetical protein 0.0089 0.0087 0.0128
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0027 0.0002 0.0002
Echinococcus granulosus tachykinin peptides receptor 99D 0.0027 0.0002 0.0001
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Brugia malayi Bromodomain containing protein 0.0319 0.0402 0.0594
Echinococcus multilocularis G protein coupled receptor 139 0.0027 0.0002 0.0001
Onchocerca volvulus 0.0292 0.0365 0.1346
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0083 0.0079 0.0078
Loa Loa (eye worm) MBCTL1 0.0119 0.0128 0.0187
Echinococcus granulosus transient receptor potential cation channel 0.0187 0.0221 0.022
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0187 0.0221 0.022
Toxoplasma gondii kelch repeat and K+ channel tetramerisation domain containing protein 0.0217 0.0262 0.4781
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0029 0.0005 0.0004
Schistosoma mansoni o-methyltransferase 0.0184 0.0217 0.0215
Loa Loa (eye worm) potassium channel tetramerisation domain containing 3 0.0217 0.0262 0.0386
Onchocerca volvulus 0.0184 0.0217 0.0797
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0441 0.0569 0.0568
Schistosoma mansoni hypothetical protein 0.0202 0.0242 0.024
Echinococcus multilocularis transient receptor potential gamma protein 0.0187 0.0221 0.022
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Echinococcus multilocularis dna polymerase eta 0.0045 0.0027 0.0026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0066
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0104 0.0108 0.0106
Loa Loa (eye worm) hypothetical protein 0.0214 0.0259 0.0381
Brugia malayi AKH receptor 0.0027 0.0002 0.0002
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0187 0.0221 0.0219
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0027 0.0002 0.0001
Echinococcus multilocularis polycomb protein SCMH1 0.0104 0.0108 0.0107
Brugia malayi PHD-finger family protein 0.0031 0.0008 0.001
Loa Loa (eye worm) thioredoxin reductase 0.0083 0.0079 0.0115
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0187 0.0221 0.022
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0187 0.0221 0.0219
Echinococcus multilocularis protein patched 0.0045 0.0027 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0004 0.0014
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0187 0.0221 0.082
Brugia malayi putative neuropeptide receptor 0.0027 0.0002 0.0002
Schistosoma mansoni ferritin 0.0107 0.0112 0.011
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0029 0.0005 0.0003
Onchocerca volvulus 0.0054 0.004 0.0139
Echinococcus granulosus Protein patched homolog 1 0.0045 0.0027 0.0026
Echinococcus multilocularis voltage dependent calcium channel 0.0187 0.0221 0.022
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0187 0.0221 0.0219
Brugia malayi G-protein coupled receptor 0.0027 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0002 0.0001
Schistosoma mansoni tyrosine kinase 0.0149 0.017 0.0167
Echinococcus multilocularis transient receptor potential cation channel 0.0187 0.0221 0.022
Brugia malayi cation channel family protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) RGC/RGC protein kinase 0.0149 0.017 0.0249
Loa Loa (eye worm) hypothetical protein 0.1546 0.2084 0.3083
Schistosoma mansoni tar DNA-binding protein 0.0471 0.061 0.0608
Mycobacterium tuberculosis Probable oxidoreductase 0.021 0.0253 0.099
Trypanosoma brucei btb/poz domain containing protein, putative 0.0217 0.0262 0.7168
Onchocerca volvulus 0.0033 0.001 0.0028
Brugia malayi Bromodomain containing protein 0.0157 0.018 0.0264
Echinococcus granulosus cyclin dependent kinase 0.009 0.0088 0.0087
Onchocerca volvulus 0.0149 0.017 0.0621
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0012 0.0011
Loa Loa (eye worm) Kv4.2 voltage-gated potassium channel 0.0217 0.0262 0.0386
Loa Loa (eye worm) cytochrome P450 family protein 0.0082 0.0078 0.0114
Echinococcus granulosus g-protein coupled receptor 0.0027 0.0002 0.0001
Echinococcus granulosus serotonin receptor 0.0027 0.0002 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0054 0.0039 0.0136
Loa Loa (eye worm) hypothetical protein 0.0169 0.0197 0.029
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0323 0.0408 0.1689
Echinococcus multilocularis potassium voltage gated channel protein 0.4957 0.6757 0.6756
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Echinococcus multilocularis solute carrier family 5 0.0043 0.0024 0.0023
Mycobacterium tuberculosis Probable lipase LipD 0.0292 0.0365 0.1433
Schistosoma mansoni glutamate receptor NMDA 0.0291 0.0364 0.0362
Onchocerca volvulus 0.0217 0.0262 0.0963
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0012 0.0016
Schistosoma mansoni hypothetical protein 0.0045 0.0027 0.0024
Trypanosoma brucei btb/poz domain containing protein, putative 0.0217 0.0262 0.7168
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0518 0.0515
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0008 0.0032
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0187 0.0221 0.022
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0062 0.005 0.0049
Echinococcus granulosus sex peptide receptor 0.0027 0.0002 0.0001
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0001 0.0003
Entamoeba histolytica hypothetical protein 0.0033 0.001 0.0109
Brugia malayi MH1 domain containing protein 0.0034 0.0012 0.0016
Echinococcus multilocularis transient receptor potential cation channel 0.0187 0.0221 0.022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0325 0.041 0.0408
Trypanosoma brucei transcription factor BTF3, putative 0.0039 0.0018 0.0477
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0033 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0951 0.1267 0.1874
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0106 0.011 0.1997
Brugia malayi neuropeptide F receptor 0.0027 0.0002 0.0002
Echinococcus granulosus transient receptor potential cation channel 0.0187 0.0221 0.022
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0027 0.0002 0.0001
Brugia malayi Heterochromatin protein 1 0.008 0.0075 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Giardia lamblia Kinase, CMGC CDK 0.009 0.0088 0.0999
Echinococcus granulosus 7tm_1 domain containing protein 0.0027 0.0002 0.0001
Schistosoma mansoni glutamate receptor kainate 0.0291 0.0364 0.0362
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0271 0.0336 0.0334
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0187 0.0221 0.0219
Echinococcus multilocularis hyperpolarization activated cyclic 0.0187 0.0221 0.022
Leishmania major cathepsin L-like protease 0.0066 0.0056 0.1513
Echinococcus granulosus 7TM GPCR rhodopsin 0.0027 0.0002 0.0001
Onchocerca volvulus 0.0054 0.004 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0008 0.0031
Loa Loa (eye worm) hypothetical protein 0.0322 0.0407 0.06
Onchocerca volvulus Terribly reduced optic lobes homolog 0.0029 0.0005 0.0011
Leishmania major cathepsin L-like protease 0.0066 0.0056 0.1513
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0315 0.0397 0.0395
Echinococcus multilocularis GPCR, family 2 0.0202 0.0242 0.0241
Brugia malayi Glutamate receptor 2 precursor 0.0291 0.0364 0.0537
Echinococcus multilocularis lipoxygenase domain containing protein 0.0089 0.0087 0.0086
Schistosoma mansoni gliotactin 0.0054 0.004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Leishmania major potassium voltage-gated channel, putative 0.0217 0.0262 0.7171
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0012 0.0011
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0054 0.0039 0.0143
Loa Loa (eye worm) latrophilin receptor protein 2 0.0202 0.0242 0.0356
Schistosoma mansoni chromobox protein 0.008 0.0075 0.0072
Echinococcus multilocularis G-protein coupled receptor, putative 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Brugia malayi hypothetical protein 0.0114 0.0122 0.0178
Echinococcus multilocularis lamin dm0 0.0172 0.0201 0.02
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Schistosoma mansoni inositol transporter 0.0043 0.0024 0.0021
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0027 0.0483
Loa Loa (eye worm) steroid hormone receptor 0.0033 0.001 0.0013
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0389 0.0498 0.0736
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0029 0.0005 0.0003
Mycobacterium ulcerans beta-lactamase 0.0292 0.0365 0.1508
Schistosoma mansoni hypothetical protein 0.0063 0.0051 0.0048
Trypanosoma cruzi cdc2-related kinase 3 0.009 0.0088 0.1598
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0062 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0017 0.005
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0009 0.021
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0048 0.0031 0.0107
Echinococcus granulosus survival motor neuron protein 1 0.1546 0.2084 0.2083
Schistosoma mansoni lozenge 0.0117 0.0125 0.0122
Plasmodium vivax thioredoxin reductase, putative 0.0083 0.0079 0.2133
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Schistosoma mansoni chromobox protein 0.008 0.0075 0.0072
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.001 0.0013
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0149 0.017 0.0249
Echinococcus multilocularis BTB:POZ domain containing protein KCTD16 0.0217 0.0262 0.0261
Schistosoma mansoni intermediate filament proteins 0.0172 0.0201 0.0199
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.6171 0.842 0.842
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0056 0.1006
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0029 0.0004 0.0123
Loa Loa (eye worm) histone methyltransferase 0.0075 0.0068 0.0099
Mycobacterium ulcerans lipase LipD 0.0292 0.0365 0.1508
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0039
Schistosoma mansoni bromodomain containing protein 0.0271 0.0337 0.0334
Echinococcus granulosus arachidonate 5 lipoxygenase 0.039 0.0499 0.0498
Mycobacterium ulcerans bacterioferritin BfrA 0.0107 0.0112 0.0451
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0027 0.0002 0.0002
Schistosoma mansoni myst-related protein 0.0033 0.001 0.0008
Loa Loa (eye worm) calcium binding EGF domain-containing protein 0.0029 0.0005 0.0006
Echinococcus granulosus glutamate receptor subunit protein glur 0.0291 0.0364 0.0363
Schistosoma mansoni hypothetical protein 0.0029 0.0005 0.0003
Brugia malayi ecdysteroid receptor 0.0033 0.001 0.0013
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0187 0.0221 0.0325
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0029 0.0004 0.0002
Mycobacterium ulcerans hypothetical protein 0.0292 0.0365 0.1508
Schistosoma mansoni hypothetical protein 0.0031 0.0008 0.0006
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0054 0.0039 0.0136
Brugia malayi Carboxylesterase family protein 0.0322 0.0407 0.06
Echinococcus multilocularis glutamate receptor 2 0.0441 0.0569 0.0568
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Leishmania major cytochrome p450-like protein 0.0054 0.0039 0.1039
Brugia malayi Doublecortin family protein 0.0089 0.0087 0.0128
Trypanosoma cruzi hypothetical protein 0.0425 0.0547 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis dnaJ subfamily B 0.2636 0.3576 0.3575
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.1038 0.1387 0.1386
Echinococcus granulosus potassium large conductance calcium activated 0.0187 0.0221 0.022
Schistosoma mansoni hypothetical protein 0.0114 0.0122 0.0119
Echinococcus multilocularis voltage gated potassium channel 0.0403 0.0518 0.0517
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0403 0.0518 0.0517
Toxoplasma gondii transporter, cation channel family protein 0.0187 0.0221 0.4034
Loa Loa (eye worm) hypothetical protein 0.0292 0.0365 0.0538
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0114 0.0122 0.1388
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0054 0.0039 0.0136
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0255 0.0314 0.5751
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0217 0.0262 0.4772
Echinococcus multilocularis sex peptide receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0639 0.084 0.1242
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0212 0.0255 0.4652
Schistosoma mansoni thyroid hormone receptor 0.0033 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0056 0.0041 0.0059
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0248 0.0305 0.0449
Echinococcus granulosus fetal alzheimer antigen falz 0.0104 0.0108 0.0107
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0212 0.0255 0.2921
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0255 0.0314 0.0313
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0187 0.0221 0.022
Echinococcus multilocularis two pore calcium channel protein 2 0.0187 0.0221 0.022
Echinococcus multilocularis zinc finger protein 0.0092 0.0091 0.009
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0187 0.0221 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0018 0.0069
Echinococcus multilocularis methyl CpG binding domain protein 2 0.007 0.0061 0.0059
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0027 0.0002 0.0002
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0119 0.0128 0.0187
Brugia malayi latrophilin 2 splice variant baaae 0.0437 0.0563 0.0832
Schistosoma mansoni hypothetical protein 0.0886 0.1179 0.1177
Loa Loa (eye worm) MH2 domain-containing protein 0.05 0.065 0.0961
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0054 0.0039 0.0136
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0114 0.0122 0.012
Loa Loa (eye worm) cytochrome P450 0.0054 0.0039 0.0055
Schistosoma mansoni SET domain protein 0.0034 0.0011 0.0009
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0257 0.0316 0.0315
Onchocerca volvulus 0.0089 0.0087 0.0316
Echinococcus multilocularis potassium voltage gated channel protein 0.0403 0.0518 0.0517
Onchocerca volvulus 0.0929 0.1238 0.4591
Loa Loa (eye worm) hypothetical protein 0.0217 0.0262 0.0386
Mycobacterium tuberculosis Probable reductase 0.0189 0.0224 0.0875
Toxoplasma gondii histone lysine methyltransferase SET1 0.0424 0.0546 1
Toxoplasma gondii hypothetical protein 0.0187 0.0221 0.4034
Brugia malayi MH2 domain containing protein 0.05 0.065 0.0961
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0187 0.0221 0.4034
Mycobacterium leprae conserved hypothetical protein 0.0292 0.0365 0.8829
Brugia malayi beta-lactamase family protein 0.0292 0.0365 0.0538
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.003 0.0006 0.0005
Schistosoma mansoni Smad4 0.0034 0.0012 0.0009
Trypanosoma cruzi ISWI complex protein 0.0063 0.0051 0.0914
Brugia malayi beta-lactamase family protein 0.0292 0.0365 0.0538
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Loa Loa (eye worm) voltage-gated potassium channel 0.0187 0.0221 0.0325
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0009 0.014
Loa Loa (eye worm) hypothetical protein 0.0054 0.0038 0.0055
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0029 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0054 0.0039 0.0036
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0187 0.0221 0.082
Plasmodium falciparum LCCL domain-containing protein 0.0089 0.0087 0.3309
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Echinococcus granulosus neuropeptide s receptor 0.0027 0.0002 0.0001
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0001 0.0003
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0291 0.0364 0.0363
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0054 0.0039 0.0136
Loa Loa (eye worm) hypothetical protein 0.0029 0.0004 0.0005
Echinococcus multilocularis BTB:POZ domain containing protein 0.0217 0.0262 0.0261
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0044 0.0042
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0187 0.0221 0.0325
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Schistosoma mansoni calcium-activated potassium channel 0.0428 0.0551 0.0549
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0187 0.0221 0.0325
Schistosoma mansoni ferritin 0.0107 0.0112 0.011
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0202 0.0242 0.0356
Echinococcus multilocularis lipoxygenase domain containing protein 0.0089 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0029 0.0004 0.0099
Loa Loa (eye worm) hypothetical protein 0.0123 0.0133 0.0196
Onchocerca volvulus 0.0054 0.0038 0.0134
Brugia malayi olfactory channel protein osm-9 0.0187 0.0221 0.0325
Trypanosoma cruzi potassium voltage-gated channel, putative 0.0217 0.0262 0.4772
Brugia malayi ion channel NompC 0.0187 0.0221 0.0325
Onchocerca volvulus 0.0029 0.0005 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Echinococcus granulosus sodium:glucose cotransporter 0.0043 0.0024 0.0023
Schistosoma mansoni smad1 5 8 and 0.0034 0.0012 0.0009
Schistosoma mansoni lamin 0.0172 0.0201 0.0199
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0189 0.0224 0.5033
Schistosoma mansoni aldehyde dehydrogenase 0.0137 0.0153 0.015
Schistosoma mansoni apoferritin-2 0.0107 0.0112 0.011
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0009 0.0138
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0056 0.1006
Schistosoma mansoni zinc finger protein 0.0092 0.0091 0.0089
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0187 0.0221 0.0325
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Trichomonas vaginalis penicillin-binding protein, putative 0.0292 0.0365 0.1353
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0106 0.011 0.3002
Echinococcus multilocularis sodium leak channel non selective protein 0.0187 0.0221 0.022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0033 0.001 0.0013
Echinococcus multilocularis RUN 0.0089 0.0087 0.0086
Loa Loa (eye worm) RNA binding protein 0.0471 0.061 0.0902
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0033 0.001 0.0013
Brugia malayi Serotonin receptor 0.0027 0.0002 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0518 0.0515
Echinococcus multilocularis expressed conserved protein 0.0099 0.0101 0.01
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.011 0.0408
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0019 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0002 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0054 0.0039 0.0136
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0009 0.021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Onchocerca volvulus 0.0058 0.0044 0.0155
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0029 0.0004 0.0088
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Mycobacterium ulcerans carboxylesterase, LipT 0.0054 0.004 0.0148
Onchocerca volvulus 0.0315 0.0397 0.1467
Mycobacterium tuberculosis Probable dehydrogenase 0.0189 0.0224 0.0875
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0054 0.0039 0.0143
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0054 0.0038 0.0136
Onchocerca volvulus 0.0029 0.0005 0.0011
Plasmodium falciparum glutathione reductase 0.0029 0.0004 0.0123
Echinococcus multilocularis mitogen activated protein kinase 0.0106 0.011 0.0109
Schistosoma mansoni tar DNA-binding protein 0.0471 0.061 0.0608
Echinococcus granulosus dnaJ subfamily B 0.2636 0.3576 0.3575
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0187 0.0221 0.0219
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0033 0.001 0.0007
Brugia malayi nuclear hormone receptor 0.0033 0.001 0.0013
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0033 0.001 0.0009
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0187 0.0221 0.022
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Trichomonas vaginalis mercuric reductase, putative 0.0029 0.0004 0.0016
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0291 0.0364 0.0363
Schistosoma mansoni transient receptor potential channel 0.0187 0.0221 0.0219
Brugia malayi hypothetical protein 0.01 0.0103 0.015
Echinococcus granulosus transient receptor potential cation channel 0.0187 0.0221 0.022
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0009 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0248 0.0305 0.0302
Loa Loa (eye worm) hypothetical protein 0.0951 0.1267 0.1874
Echinococcus multilocularis transient receptor potential cation channel 0.0187 0.0221 0.022
Loa Loa (eye worm) ion channel NompC 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0323 0.0408 0.1605
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.01 0.0102 0.1168
Loa Loa (eye worm) hypothetical protein 0.0292 0.0365 0.0538
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0403 0.0518 0.0517
Schistosoma mansoni glutamate receptor NMDA 0.239 0.324 0.3239
Trypanosoma brucei PAB1-binding protein , putative 0.01 0.0103 0.279
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Brugia malayi Pre-SET motif family protein 0.1751 0.2364 0.3497
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0044 0.0042
Schistosoma mansoni steroid hormone receptor ad4bp 0.0033 0.001 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0217 0.0262 0.0259
Echinococcus granulosus lipoxygenase domain containing protein 0.0089 0.0087 0.0086
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0403 0.0518 0.0517
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0291 0.0364 0.0363
Brugia malayi AMP-binding enzyme family protein 0.0054 0.0038 0.0055
Schistosoma mansoni smad1 5 8 and 0.0034 0.0012 0.0009
Schistosoma mansoni voltage-gated potassium channel 0.0217 0.0262 0.0259
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.003 0.0029
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0008 0.0125
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.003 0.0042
Brugia malayi PHD-finger family protein 0.003 0.0006 0.0008
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0747 0.0988 1
Echinococcus multilocularis cyclin dependent kinase 1 0.009 0.0088 0.0087
Entamoeba histolytica hypothetical protein 0.0149 0.017 0.1939
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0066
Leishmania major extracellular receptor, putative 0.0149 0.017 0.4641
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.0004 0.0066
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0106 0.011 0.1998
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0149 0.017 0.0249
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0187 0.0221 0.022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.0049 0.0183
Schistosoma mansoni sodium/solute symporter 0.0043 0.0024 0.0021
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0187 0.0221 0.022
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0033 0.001 0.0009
Loa Loa (eye worm) glutamate receptor 1 0.0291 0.0364 0.0537
Brugia malayi glutathione reductase 0.0083 0.0079 0.0115
Schistosoma mansoni hypothetical protein 0.0638 0.084 0.0838
Echinococcus multilocularis expressed protein 0.0107 0.0112 0.0111
Echinococcus granulosus tumor protein p63 0.1482 0.1995 0.1995
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0092 0.0091 0.0134
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0441 0.0569 0.0568
Plasmodium falciparum phd finger protein, putative 0.0031 0.0008 0.0262
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0054 0.0039 0.0143
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0187 0.0221 0.0325
Echinococcus granulosus metabotropic glutamate receptor 2 0.0149 0.017 0.0168
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.009 0.0088 0.0129
Echinococcus granulosus expressed conserved protein 0.0099 0.0101 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0009 0.0018
Brugia malayi hypothetical protein 0.1546 0.2084 0.3083
Echinococcus multilocularis neuropeptide receptor A26 0.0027 0.0002 0.0001
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0107 0.0112 0.1995
Echinococcus granulosus ryanodine receptor 44f 0.0187 0.0221 0.022
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Brugia malayi G-protein coupled receptor 0.0027 0.0002 0.0002
Schistosoma mansoni cytochrome P450 0.0054 0.0039 0.0036
Giardia lamblia NADH oxidase lateral transfer candidate 0.0029 0.0004 0.0037
Schistosoma mansoni glutamate receptor AMPA 0.0291 0.0364 0.0362
Schistosoma mansoni thyroid hormone receptor 0.0033 0.001 0.0007
Echinococcus granulosus allatostatin A receptor 0.0027 0.0002 0.0001
Brugia malayi Transient-receptor-potential like protein 0.0187 0.0221 0.0325
Schistosoma mansoni BC026374 protein (S09 family) 0.0054 0.004 0.0037
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0073 0.0064 0.0062
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0066
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0029 0.0005 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0054 0.0038 0.0136
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0323 0.0408 1
Echinococcus granulosus low density lipoprotein receptor protein 0.0029 0.0005 0.0004
Brugia malayi Smad1 0.0034 0.0012 0.0016
Trypanosoma brucei ISWI complex protein 0.0063 0.0051 0.1365
Echinococcus multilocularis cyclin dependent kinase 1 0.009 0.0088 0.0087
Echinococcus granulosus RUN 0.0089 0.0087 0.0086
Plasmodium vivax ataxin-2 like protein, putative 0.01 0.0103 0.279
Schistosoma mansoni hypothetical protein 0.0044 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.003 0.0006 0.0007
Loa Loa (eye worm) TYRA-2 protein 0.0027 0.0002 0.0002
Schistosoma mansoni voltage-gated ion channel 0.0187 0.0221 0.0219
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0292 0.0365 0.1433
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0062 0.0049 0.0183
Trichomonas vaginalis D-aminoacylase, putative 0.0292 0.0365 0.1353
Brugia malayi K+ channel tetramerisation domain containing protein 0.0217 0.0262 0.0386
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0149 0.017 0.0168
Brugia malayi beta-NAC-like protein 0.0039 0.0018 0.0026
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0009 0.021
Brugia malayi hypothetical protein 0.0054 0.004 0.0057
Echinococcus granulosus acetylcholinesterase 0.0322 0.0407 0.0406
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0009 0.0219
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Echinococcus multilocularis transient receptor potential cation channel 0.0187 0.0221 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0062
Trypanosoma cruzi PAB1-binding protein , putative 0.01 0.0103 0.1862
Schistosoma mansoni tar DNA-binding protein 0.0471 0.061 0.0608
Brugia malayi Dopamine receptor 0.0027 0.0002 0.0002
Brugia malayi CXXC zinc finger family protein 0.0214 0.0258 0.038
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0187 0.0221 0.022
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0187 0.0221 0.0812
Brugia malayi larval opioid receptor 0.0027 0.0002 0.0002
Schistosoma mansoni neuroligin 3 (S09 family) 0.0054 0.004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0428 0.0551 0.0814
Schistosoma mansoni transient receptor potential channel 4 0.0187 0.0221 0.0219
Trichomonas vaginalis spcc417.12 protein, putative 0.0054 0.004 0.0147
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0187 0.0221 0.0219
Echinococcus multilocularis low density lipoprotein receptor protein 0.0029 0.0005 0.0004
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0056 0.1006
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0054 0.0039 0.0691
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1863 0.2518 1
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0033 0.001 0.0013
Echinococcus granulosus glutamate NMDA receptor subunit 0.0291 0.0364 0.0363
Echinococcus granulosus low density lipoprotein receptor ldl 0.0029 0.0005 0.0004
Onchocerca volvulus 0.0292 0.0365 0.1346
Onchocerca volvulus 0.0172 0.0201 0.0738
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0054 0.0039 0.0136
Trypanosoma cruzi major cysteine proteinase, putative 0.0052 0.0036 0.0651
Echinococcus granulosus neuropeptide receptor 0.0027 0.0002 0.0001
Echinococcus granulosus receptor type guanylyl cyclase 0.0149 0.017 0.0168
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0315 0.0397 0.0586
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0061 0.0048 0.0862
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0104 0.0108 0.0107
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0054 0.0038 0.0143
Echinococcus multilocularis cpg binding protein 0.0234 0.0285 0.0284
Echinococcus granulosus cytochrome P450 2K1 0.0054 0.0039 0.0037
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0017 0.0016
Echinococcus multilocularis transfer RNA-Gly 0.0403 0.0518 0.0517
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0187 0.0221 0.022
Echinococcus multilocularis neuropeptide s receptor 0.0027 0.0002 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Brugia malayi Steroid receptor seven-up type 2 0.0033 0.001 0.0013
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0009 0.0147
Echinococcus multilocularis two pore calcium channel protein 1 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0325 0.041 0.0409
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0018
Leishmania major basic transcription factor 3a, putative 0.0039 0.0018 0.0488
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Plasmodium vivax glutathione reductase, putative 0.0083 0.0079 0.2133
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Echinococcus granulosus chromobox protein 1 0.008 0.0075 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0033 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.001 0.0013
Trichomonas vaginalis esterase, putative 0.0292 0.0365 0.1353
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0187 0.0221 0.0325
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0008 0.0125
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0017 0.0426
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.474 0.646 0.646
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0054 0.004 0.014
Trypanosoma brucei btb/poz domain containing protein, putative 0.0217 0.0262 0.7168
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Echinococcus granulosus muscleblind protein 0.0951 0.1267 0.1266
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0002 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.0292 0.0365 0.1353
Echinococcus multilocularis acetylcholinesterase 0.0322 0.0407 0.0406
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0441 0.0569 0.0568
Loa Loa (eye worm) hypothetical protein 0.004 0.002 0.0028
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0747 0.0988 0.3914
Loa Loa (eye worm) TAR-binding protein 0.0471 0.061 0.0902
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0054 0.0039 0.0143
Schistosoma mansoni coup transcription factor 0.0033 0.001 0.0007
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0012 0.0009
Echinococcus multilocularis mitogen activated protein kinase 3 0.0106 0.011 0.0109
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0027 0.0002 0.0001
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0027 0.0002 0.0001
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Loa Loa (eye worm) ryanodine receptor 0.0187 0.0221 0.0325
Echinococcus granulosus tar DNA binding protein 0.0471 0.061 0.0609
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Loa Loa (eye worm) glutamate receptor 0.0149 0.017 0.0249
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0054 0.0039 0.0143
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0027 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0291 0.0364 0.0362
Trypanosoma cruzi hypothetical protein, conserved 0.0217 0.0262 0.4772
Brugia malayi MH2 domain containing protein 0.0034 0.0012 0.0016
Trypanosoma brucei potassium voltage-gated channel, putative 0.0217 0.0262 0.7168
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Loa Loa (eye worm) hypothetical protein 0.0639 0.084 0.1242
Trypanosoma brucei DNA polymerase eta, putative 0.0045 0.0027 0.0716
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0043 0.0024 0.0023
Echinococcus multilocularis Niemann Pick C1 protein 0.0151 0.0172 0.0171
Loa Loa (eye worm) hypothetical protein 0.004 0.002 0.0028
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0009 0.014
Echinococcus multilocularis Niemann Pick C1 protein 0.0106 0.011 0.0109
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0403 0.0518 0.0517
Brugia malayi Importin beta-1 subunit 0.0032 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Echinococcus granulosus neuropeptide FF receptor 2 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0119 0.0128 0.0187
Toxoplasma gondii transporter, cation channel family protein 0.0187 0.0221 0.4034
Loa Loa (eye worm) heterochromatin protein 1 0.008 0.0075 0.0109
Loa Loa (eye worm) hypothetical protein 0.0157 0.018 0.0265
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0002 0.0001
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0054 0.004 0.0147
Trypanosoma cruzi cruzipain precursor, putative 0.0066 0.0056 0.1006
Schistosoma mansoni smad1 5 8 and 0.0034 0.0012 0.0009
Echinococcus granulosus ecdysone induced protein 78C 0.0033 0.001 0.0009
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0662 0.0871 1
Schistosoma mansoni tar DNA-binding protein 0.0471 0.061 0.0608
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0026 0.009
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0002 0.0001
Echinococcus granulosus beta LACTamase domain containing family member 0.0292 0.0365 0.0363
Toxoplasma gondii NADPH-glutathione reductase 0.0029 0.0004 0.0059
Schistosoma mansoni myst-related protein 0.0033 0.001 0.0008
Plasmodium vivax K+ channel tetramerisation domain containing protein 0.0217 0.0262 0.7168
Mycobacterium ulcerans aldehyde dehydrogenase 0.0137 0.0153 0.0621
Onchocerca volvulus Alhambra homolog 0.0031 0.0008 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0008 0.0031
Schistosoma mansoni glutaminase 0.0306 0.0384 0.0382
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0054 0.0038 0.0143
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.009 0.0088 0.1596
Echinococcus multilocularis cyclin dependent kinase 5 0.009 0.0088 0.0087
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0083 0.0079 0.0078
Echinococcus multilocularis Polycystic kidney disease protein 0.0089 0.0087 0.0086
Brugia malayi GnHR receptor homolog 0.0027 0.0002 0.0002
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0187 0.0221 0.6053
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0027 0.0002 0.0002
Loa Loa (eye worm) PHD-finger family protein 0.0084 0.0081 0.0118
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.0009 0.0145
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0033 0.001 0.0009
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0471 0.061 0.0902
Brugia malayi putative neuropeptide receptor NPR1 0.0027 0.0002 0.0002
Brugia malayi TAR-binding protein 0.0471 0.061 0.0902
Brugia malayi Cytochrome P450 family protein 0.0178 0.0209 0.0307
Brugia malayi cell division control protein 2 homolog 0.009 0.0088 0.0129
Trypanosoma brucei cytochrome P450, putative 0.0082 0.0078 0.2115
Schistosoma mansoni hypothetical protein 0.0044 0.0025 0.0023
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.001 0.0013
Onchocerca volvulus 0.0029 0.0005 0.0011
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0029 0.0005 0.0006
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0054 0.0039 0.0143
Echinococcus granulosus two pore calcium channel protein 2 0.0187 0.0221 0.022
Echinococcus multilocularis calcium activated potassium channel 0.0189 0.0224 0.0222
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0009 0.0294
Schistosoma mansoni RAR-like nuclear receptor 0.0033 0.001 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0054 0.0039 0.0136
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0033 0.001 0.0009
Echinococcus granulosus G protein coupled receptor 139 0.0027 0.0002 0.0001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0187 0.0221 0.4034
Echinococcus multilocularis high affinity choline transporter 1 0.0389 0.0498 0.0497
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0043 0.0024 0.0415
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.003 0.0006 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0044 0.0064
Giardia lamblia GTOR 0.0047 0.003 0.033
Onchocerca volvulus 0.0217 0.0262 0.0963
Brugia malayi cytochrome P450 0.0054 0.0039 0.0055
Echinococcus granulosus somatostatin receptor 0.0027 0.0002 0.0001
Echinococcus granulosus transient receptor potential cation channel 0.0187 0.0221 0.022
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0033 0.001 0.0013
Echinococcus granulosus solute carrier family 5 0.0043 0.0024 0.0023
Schistosoma mansoni methyl-cpg binding protein mbd 0.007 0.0061 0.0058
Entamoeba histolytica acyl-coA synthetase, putative 0.0054 0.0038 0.0433
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0058 0.0044 0.0042
Loa Loa (eye worm) hypothetical protein 0.0054 0.0038 0.0055
Trypanosoma brucei BTB/POZ domain/Regulator of chromosome condensation (RCC1) repeat, putative 0.0217 0.0262 0.7168
Loa Loa (eye worm) glutaminase 2 0.0306 0.0384 0.0567
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0033
Brugia malayi Dopamine receptor protein 2 0.0027 0.0002 0.0002
Echinococcus granulosus expressed protein 0.0107 0.0112 0.0111
Schistosoma mansoni patched 1 0.0045 0.0027 0.0025
Mycobacterium leprae Probable lipase LipE 0.0292 0.0365 0.8829
Brugia malayi cation channel family protein 0.0187 0.0221 0.0325
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0017 0.005
Echinococcus multilocularis NMDA receptor 0.0291 0.0364 0.0363
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.0049 0.0183
Brugia malayi AMP-binding enzyme family protein 0.0054 0.0038 0.0055
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0054 0.0039 0.0143
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0137 0.0153 0.059
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0009 0.0008
Onchocerca volvulus 0.0058 0.0044 0.0155
Trichomonas vaginalis glutaminase, putative 0.0306 0.0384 0.1427
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0083 0.0079 0.0296
Echinococcus multilocularis survival motor neuron protein 1 0.1546 0.2084 0.2083
Brugia malayi mKIAA0176 protein 0.0217 0.0262 0.0386
Toxoplasma gondii cytochrome p450 superfamily protein 0.0054 0.0039 0.0687
Echinococcus granulosus short transient receptor potential channel 6 0.0187 0.0221 0.022
Mycobacterium ulcerans hypothetical protein 0.0054 0.0038 0.0143
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0054 0.0039 0.0136
Echinococcus granulosus SAM and MBT domain containing protein 0.0104 0.0108 0.0107
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.003 0.0028
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0292 0.0365 0.0538
Brugia malayi Latrophilin receptor protein 2 0.0202 0.0242 0.0356
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0033 0.001 0.0007
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.009 0.0088 0.0129
Brugia malayi Glutamate receptor 1 precursor 0.0291 0.0364 0.0537
Loa Loa (eye worm) hypothetical protein 0.0437 0.0563 0.0832
Echinococcus granulosus lysine specific demethylase 5A 0.0058 0.0044 0.0043
Trichomonas vaginalis ferritin, putative 0.0107 0.0112 0.0416
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Brugia malayi Carboxylesterase family protein 0.0054 0.004 0.0057
Loa Loa (eye worm) carboxylesterase 0.0054 0.004 0.0057
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.0038 0.0143
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0031 0.0115
Trichomonas vaginalis D-aminoacylase, putative 0.0292 0.0365 0.1353
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0248 0.0305 0.0304
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0054 0.0039 0.0143
Toxoplasma gondii ABC1 family protein 0.0292 0.0365 0.6669
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0054 0.0039 0.0136
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0441 0.0569 0.0568
Loa Loa (eye worm) hypothetical protein 0.0172 0.0201 0.0296
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0747 0.0988 0.4119
Loa Loa (eye worm) hypothetical protein 0.0031 0.0008 0.001

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 7.2 % Stimulation of [35S]GTPgammaS binding in human brain cortical membrane relative to control ChEMBL. 16650985
EC50 (functional) = 1.84 nM Stimulation of [35S]GTPgammaS binding at kappa opioid receptor in human brain cortical membrane ChEMBL. 16650985
ED50 (functional) = 10.1 ug/kg Analgesic activity in iv dosed SHR mouse by tail flick assay ChEMBL. 16650985
ED50 (functional) = 11.2 ug/kg Analgesic activity in iv dosed SHR mouse by writhing assay ChEMBL. 16650985
ED50 (functional) = 17.6 ug/kg Analgesic activity in iv dosed SHR mouse by hot plate assay ChEMBL. 16650985
ED50 (functional) = 28.4 ug/kg Analgesic activity in iv dosed SHR mouse by tail clip assay ChEMBL. 16650985
Efficacy (functional) = 35 % Agonist activity at kappa opioid receptor in human brain cortical membrane relative to U69593 ChEMBL. 16650985
Efficacy (functional) = 100 % Analgesic activity in iv dosed SHR mouse by writhing assay ChEMBL. 16650985
Efficacy (functional) = 100 % Analgesic activity in iv dosed SHR mouse by hot plate assay ChEMBL. 16650985
Efficacy (functional) = 100 % Analgesic activity in iv dosed SHR mouse by tail flick assay ChEMBL. 16650985
Efficacy (functional) = 100 % Analgesic activity in iv dosed SHR mouse by tail clip assay ChEMBL. 16650985

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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