Detailed information for compound 1201716

Basic information

Technical information
  • TDR Targets ID: 1201716
  • Name: N-(7,7-dimethyl-5-oxo-6,8-dihydroquinazolin-2 -yl)-2-(4-ethylphenoxy)acetamide
  • MW: 353.415 | Formula: C20H23N3O3
  • H donors: 1 H acceptors: 4 LogP: 3.18 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccc(cc1)OCC(=O)Nc1ncc2c(n1)CC(CC2=O)(C)C
  • InChi: 1S/C20H23N3O3/c1-4-13-5-7-14(8-6-13)26-12-18(25)23-19-21-11-15-16(22-19)9-20(2,3)10-17(15)24/h5-8,11H,4,9-10,12H2,1-3H3,(H,21,22,23,25)
  • InChiKey: ICIHHGJTCZSGMX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(4-ethylphenoxy)-N-(5-keto-7,7-dimethyl-6,8-dihydroquinazolin-2-yl)acetamide
  • N-(7,7-dimethyl-5-oxo-6,8-dihydroquinazolin-2-yl)-2-(4-ethylphenoxy)ethanamide
  • ZINC02412960
  • STOCK4S-46057
  • SMR000044609
  • BAS 11216246
  • MLS000082732

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens snurportin 1 No references
Homo sapiens thyroid stimulating hormone receptor Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens karyopherin (importin) beta 1 No references
Homo sapiens parathyroid hormone 1 receptor Starlite/ChEMBL No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens RAN, member RAS oncogene family No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum ko:K04588 secretin receptor, putative Get druggable targets OG5_139196 All targets in OG5_139196
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0018 0.0015 0.0072
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0038 0.007 0.0351
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0036 0.1403
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0065 0.034
Brugia malayi fructose-bisphosphate aldolase 1 0.0092 0.0217 0.1436
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0088 0.0912
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0143
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0046 0.0092 0.0385
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0092 0.0217 0.8609
Loa Loa (eye worm) transcription factor SMAD2 0.0129 0.0319 0.2133
Echinococcus granulosus microtubule associated protein 2 0.0697 0.1877 1
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0058 0.2224
Leishmania major cytochrome p450-like protein 0.0014 0.0005 0.0167
Brugia malayi hypothetical protein 0.0165 0.0417 0.278
Echinococcus multilocularis musashi 0.0027 0.004 0.0163
Trypanosoma cruzi Iron/manganese superoxide dismutases, C-terminal domain containing protein, putative 0.0017 0.0011 0.0439
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0018 0.01
Brugia malayi Steroid receptor seven-up type 2 0.0038 0.007 0.0453
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0076 0.032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0118
Onchocerca volvulus 0.0114 0.0279 0.447
Trypanosoma brucei trypanothione reductase 0.0104 0.0252 1
Schistosoma mansoni lipoxygenase 0.0122 0.03 0.158
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0104 0.0252 0.0248
Trichomonas vaginalis superoxide dismutase [fe], putative 0.0067 0.015 0.0632
Brugia malayi hypothetical protein 0.0036 0.0065 0.0417
Onchocerca volvulus 0.0101 0.0242 0.3873
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0002 0.0002
Mycobacterium tuberculosis Probable reductase 0.0099 0.0237 0.0232
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0079
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0068 0.0153 0.081
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0134 0.5213
Loa Loa (eye worm) hypothetical protein 0.0041 0.0078 0.0523
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0065 0.017
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0068 0.0153 0.0794
Trichomonas vaginalis esterase, putative 0.0036 0.0065 0.0274
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0005 0.003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0134 0.0338
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.0114 0.0279 0.1174
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0019 0.0733
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0664
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0065 0.2556
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1404 0.3818 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0106 0.4218
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0013 0.0041
Trypanosoma cruzi superoxide dismutase, putative 0.0038 0.007 0.2768
Echinococcus granulosus transcription factor eb 0.0116 0.0285 0.1512
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0295 0.0775 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0061 0.0405
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0021 0.0106
Toxoplasma gondii ferodoxin FD 0.0028 0.0042 0.1533
Schistosoma mansoni microtubule-associated protein tau 0.0697 0.1877 1
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0141 0.0728
Loa Loa (eye worm) RecQ helicase 0.0022 0.0024 0.0163
Trypanosoma brucei protein kinase, putative 0.0051 0.0106 0.4175
Echinococcus multilocularis zinc finger protein 0.0022 0.0025 0.01
Leishmania major DNA polymerase kappa, putative 0.0019 0.0019 0.0733
Brugia malayi nuclear receptor RXR 0.002 0.0021 0.0121
Schistosoma mansoni hypothetical protein 0.0557 0.1495 0.7958
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0099 0.0237 0.0232
Onchocerca volvulus 0.0031 0.0052 0.0821
Echinococcus multilocularis snurportin 1 0.0372 0.0986 0.4162
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0092 0.0217 0.8609
Schistosoma mansoni adrenodoxin 0.0028 0.0042 0.0203
Treponema pallidum replicative DNA helicase (dnaB) 0.0417 0.111 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0076 0.0398
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0065 0.0159
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0092 0.0217 0.1135
Loa Loa (eye worm) beta-lactamase 0.0036 0.0065 0.0435
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0043 0.018
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0038 0.007 0.0351
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0058 0.0243
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0412 0.1097 0.2864
Echinococcus multilocularis pyruvate kinase 0.0017 0.0013 0.0048
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0068 0.0153 0.0647
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0106 0.4218
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0009
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0046 0.0092 0.0389
Schistosoma mansoni hydrolase 0.0038 0.007 0.0351
Schistosoma mansoni retinoic acid receptor RXR 0.0038 0.007 0.0351
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0076 0.032
Loa Loa (eye worm) hypothetical protein 0.0038 0.007 0.047
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0021 0.0399
Plasmodium vivax superoxide dismutase [Fe], putative 0.0038 0.007 0.2623
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0018 0.0087
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0021 0.0024 0.0922
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0038 0.007 0.0453
Onchocerca volvulus 0.005 0.0102 0.1636
Trichomonas vaginalis cdc25b, putative 0.0114 0.0279 0.1178
Brugia malayi Pre-SET motif family protein 0.0031 0.005 0.0317
Brugia malayi SWIRM domain containing protein 0.0021 0.0023 0.0138
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.005 0.0243
Trypanosoma cruzi adrenodoxin precursor, putative 0.0028 0.0042 0.1674
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0005 0.0011
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0021 0.0106
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0065 0.0274
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0092 0.0217 0.8609
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0083
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0099
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0058 0.215
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.03 0.0788 0.2054
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0141 0.0728
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0075 0.0195
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0028 0.0042 0.1674
Trypanosoma cruzi iron superoxide dismutase, putative 0.0046 0.0091 0.3614
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0116 0.0285 0.1891
Echinococcus multilocularis muscleblind protein 0.0312 0.0821 0.3468
Loa Loa (eye worm) hypothetical protein 0.0041 0.0078 0.0524
Mycobacterium tuberculosis Possible oxygenase 0.0028 0.0042 0.0038
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0065 0.0061
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0015 0.0072
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0021 0.0121
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0019 0.0664
Echinococcus granulosus fructose bisphosphate aldolase class I 0.0092 0.0217 0.115
Leishmania major hypothetical protein, conserved 0.0028 0.0042 0.1674
Toxoplasma gondii superoxide dismutase 0.0067 0.015 0.5874
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0106 0.4218
Leishmania major superoxide dismutase, putative 0.0038 0.007 0.2768
Loa Loa (eye worm) hypothetical protein 0.0039 0.0072 0.0479
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0068 0.0153 0.0642
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0435
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0106 0.056
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0018 0.0015 0.0055
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0028 0.0042 0.1533
Brugia malayi nuclear hormone receptor family member odr-7 0.0018 0.0015 0.0081
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0033 0.017
Schistosoma mansoni hypothetical protein 0.0036 0.0065 0.0323
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0131 0.0857
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0058 0.0369
Schistosoma mansoni cpg binding protein 0.0039 0.0071 0.0356
Trypanosoma cruzi adrenodoxin precursor, putative 0.0028 0.0042 0.1674
Mycobacterium tuberculosis Conserved protein 0.0036 0.0065 0.0061
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0099 0.0237 0.0232
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0065 0.2501
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0023 0.0117
Brugia malayi beta-lactamase 0.0036 0.0065 0.0418
Leishmania major pyruvate kinase 0.0034 0.0058 0.2281
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0986 0.6594
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0048 0.0097 0.0406
Chlamydia trachomatis ferredoxin 0.0028 0.0042 0.038
Brugia malayi jmjC domain containing protein 0.0017 0.0012 0.0061
Toxoplasma gondii superoxide dismutase SOD2 0.0067 0.015 0.5874
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0005 0.003
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0036 0.0183
Wolbachia endosymbiont of Brugia malayi superoxide dismutase, SodA 0.0067 0.015 0.1007
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0106 0.0449
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.0065 0.0158
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0099
Schistosoma mansoni thyroid hormone receptor 0.0038 0.007 0.0351
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.005 0.1841
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0068 0.0153 0.601
Brugia malayi hypothetical protein 0.0018 0.0015 0.0081
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0076 0.3008
Brugia malayi Cytochrome P450 family protein 0.0053 0.011 0.0721
Schistosoma mansoni coup transcription factor 0.0038 0.007 0.0351
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0099
Leishmania major ferredoxin, 2fe-2s-like protein 0.0028 0.0042 0.1674
Onchocerca volvulus 0.0035 0.0061 0.0965
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0035 0.1383
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.011 0.0738
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.002 0.0021 0.0139
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0139
Trypanosoma cruzi iron superoxide dismutase, putative 0.0067 0.015 0.5943
Echinococcus multilocularis 0.0021 0.0023 0.0093
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0019 0.0733
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0664
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0046 0.0092 0.1046
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0088 0.3473
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0013 0.0043
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0022 0.0113
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0065 0.243
Echinococcus multilocularis thyroid hormone receptor alpha 0.0038 0.007 0.0292
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0076 0.3008
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0015 0.0055
Loa Loa (eye worm) hypothetical protein 0.0035 0.0061 0.0407
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0065 0.0681
Brugia malayi indoleamine 2,3-dioxygenase 0.0557 0.1495 1
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0068 0.0153 0.6076
Schistosoma mansoni hypothetical protein 0.0101 0.0242 0.1267
Onchocerca volvulus Protein ultraspiracle homolog 0.0038 0.007 0.1123
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0015 0.0072
Schistosoma mansoni nuclear hormone receptor 0.0038 0.007 0.0351
Mycobacterium ulcerans hypothetical protein 0.0142 0.0355 0.092
Loa Loa (eye worm) thioredoxin reductase 0.0104 0.0252 0.1686
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0065 0.0323
Onchocerca volvulus Superoxide dismutase [Mn], mitochondrial homolog 0.0067 0.015 0.2399
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0068 0.0153 0.589
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0036 0.0145
Loa Loa (eye worm) hypothetical protein 0.0067 0.015 0.1003
Mycobacterium ulcerans oxygenase 0.0028 0.0042 0.0099
Brugia malayi Rhodanese-like domain containing protein 0.0114 0.0279 0.1852
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0144 0.0361 0.0934
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0058 0.2281
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0028 0.0042 0.0284
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0199
Brugia malayi Cytochrome P450 family protein 0.0014 0.0005 0.0012
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0018 0.0118
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0036 0.1403
Trichomonas vaginalis cdc25b, putative 0.0114 0.0279 0.1178
Echinococcus multilocularis muscleblind protein 1 0.0312 0.0821 0.3468
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.007 0.0453
Schistosoma mansoni hypothetical protein 0.0019 0.0018 0.007
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0038 0.007 0.0351
Brugia malayi cytochrome P450 0.0014 0.0005 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.007 0.0453
Mycobacterium ulcerans monoamine oxidase 0.0021 0.0023 0.0049
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0412 0.1097 0.1093
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0065 0.0268
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0106 0.4218
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0664
Loa Loa (eye worm) nuclear hormone receptor 0.0018 0.0015 0.0099
Schistosoma mansoni amine oxidase 0.0021 0.0023 0.01
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0027 0.0038 0.0238
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0068 0.0153 0.6047
Leishmania major trypanothione reductase 0.0104 0.0252 1
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0092 0.0217 0.0912
Trypanosoma cruzi ISWI complex protein 0.0015 0.0008 0.0292
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0065 0.2501
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0092 0.0217 0.8586
Schistosoma mansoni importin beta-1 0.0035 0.0061 0.0301
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0005 0.0017
Schistosoma mansoni inositol monophosphatase 0.0045 0.0088 0.0444
Echinococcus granulosus ecdysone induced protein 78C 0.0038 0.007 0.0368
Plasmodium vivax thioredoxin reductase, putative 0.0104 0.0252 1
Brugia malayi hypothetical protein 0.0016 0.001 0.0051
Schistosoma mansoni survival motor neuron protein 0.0101 0.0242 0.1267
Echinococcus granulosus thyroid hormone receptor alpha 0.0018 0.0015 0.0072
Schistosoma mansoni cpg binding protein 0.0039 0.0071 0.0356
Plasmodium falciparum glutathione reductase 0.0036 0.0065 0.2202
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0088 0.3363
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0013 0.0047
Echinococcus multilocularis ecdysone induced protein 78C 0.0038 0.007 0.0292
Echinococcus multilocularis RUN 0.002 0.0021 0.0084
Schistosoma mansoni nuclear receptor 0.0018 0.0015 0.0055
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0065 0.0208
Echinococcus granulosus histone lysine methyltransferase setb 0.0048 0.0097 0.0512
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0161 0.6349
Trypanosoma brucei iron superoxide dismutase 0.0067 0.015 0.5913
Onchocerca volvulus 0.0027 0.004 0.0637
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0065 0.243
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0065 0.0274
Echinococcus granulosus pyruvate kinase 0.0034 0.0058 0.03
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0295 0.0776 0.0771
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0046 0.0092 0.0974
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0065 0.0268
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0076 0.0398
Brugia malayi Cytochrome P450 family protein 0.0014 0.0005 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0775 0.3275
Echinococcus multilocularis FTZ F1 alpha 0.0038 0.007 0.0292
Loa Loa (eye worm) hypothetical protein 0.0105 0.0254 0.1702
Entamoeba histolytica hypothetical protein 0.0028 0.0043 0.0318
Trichomonas vaginalis Ferredoxin 2 0.0028 0.0042 0.0178
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0065 0.0159
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0106 0.4218
Loa Loa (eye worm) steroid hormone receptor 0.0038 0.007 0.047
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0019 0.0733
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0102 0.0519
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0018 0.0069
Loa Loa (eye worm) hypothetical protein 0.0312 0.0821 0.5496
Schistosoma mansoni hypothetical protein 0.0021 0.0022 0.0096
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0065 0.0061
Trichomonas vaginalis Ferredoxin 7 0.0028 0.0042 0.0178
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0065 0.0269
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0021 0.0023 0.0478
Brugia malayi jmjC domain containing protein 0.0063 0.0139 0.0916
Plasmodium falciparum importin beta, putative 0.0035 0.0061 0.2045
Mycobacterium tuberculosis Superoxide dismutase [FE] SodA 0.0067 0.015 0.0145
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.005 0.0243
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0021 0.0023 0.0728
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0019 0.0733
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0045 0.0088 0.3497
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0076 0.0382
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0013 0.0043
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0002 0.0051
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0019 0.0664
Leishmania major hypothetical protein, conserved 0.0025 0.0035 0.1383
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0295 0.0776 0.2022
Schistosoma mansoni ran 0.0026 0.0036 0.0166
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0065 0.2407
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.017 0.0885
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0058 0.0243
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0046 0.0092 0.3534
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0078 0.0411
Plasmodium falciparum superoxide dismutase [Fe] 0.0038 0.007 0.2424
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0019 0.0108
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0012 0.0055
Echinococcus granulosus Adrenodoxin mitochondrial 0.0028 0.0042 0.0219
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0005 0.0167
Schistosoma mansoni hypothetical protein 0.0557 0.1495 0.7958
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0023 0.0728
Brugia malayi Thioredoxin reductase 0.0104 0.0252 0.1671
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0028 0.0042 0.0266
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0021 0.0023 0.0478
Treponema pallidum hypothetical protein 0.0142 0.0355 0.2783
Onchocerca volvulus Bile acid receptor homolog 0.0038 0.007 0.1123
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0099 0.0237 0.062
Echinococcus multilocularis 0.0014 0.0005 0.0013
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0065 0.2202
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0061 0.235
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0045 0.0088 0.3497
Echinococcus multilocularis thioredoxin glutathione reductase 0.0105 0.0253 0.1066
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0068 0.0153 0.0642
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0043 0.1688
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.007 0.0292
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0874 0.2365 1
Trichomonas vaginalis superoxide dismutase [fe], putative 0.0067 0.015 0.0632
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0014 0.0005 0.0167
Trichomonas vaginalis Ferredoxin 6 0.0028 0.0042 0.0178
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0028 0.0042 0.0099
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0038 0.007 0.047
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0079
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0065 0.2517
Leishmania major superoxide dismutase, putative 0.0038 0.007 0.2768
Schistosoma mansoni thyroid hormone receptor 0.0038 0.007 0.0351
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0043 0.018
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0068 0.0153 0.039
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0015 0.0057
Loa Loa (eye worm) hypothetical protein 0.005 0.0102 0.0685
Loa Loa (eye worm) hypothetical protein 0.0025 0.0035 0.0235
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0038 0.007 0.047
Trypanosoma brucei iron superoxide dismutase A, mitochondrial 0.0067 0.015 0.5913
Giardia lamblia DINP protein human, muc B family 0.0019 0.0019 0.0079
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.004 0.025
Schistosoma mansoni zinc finger protein 0.0018 0.0015 0.0055
Brugia malayi follicle stimulating hormone receptor 0.028 0.0733 0.4895
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0021 0.0023 0.01
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0023 0.0728
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.007 0.0368
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0097 0.0496
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0092 0.0217 0.115
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0232 0.0603 0.0598
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0065 0.0061
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0038 0.007 0.0292
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0038 0.007 0.0453
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0775 0.3275
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.0139 0.0736
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0134 0.0559
Schistosoma mansoni pyruvate kinase 0.0017 0.0013 0.0044
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0065 0.2501
Mycobacterium tuberculosis Probable oxidoreductase 0.0126 0.031 0.0305
Brugia malayi jmjC domain containing protein 0.0017 0.0012 0.0061
Echinococcus granulosus pyruvate kinase 0.0017 0.0013 0.0061
Schistosoma mansoni rab6-interacting 0.002 0.0021 0.009
Echinococcus multilocularis tumor protein p63 0.0341 0.0901 0.3806
Echinococcus granulosus nuclear receptor nhr 48 0.0018 0.0015 0.0072
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0043 0.018
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0065 0.0339
Mycobacterium ulcerans dehydrogenase 0.0021 0.0023 0.0049
Toxoplasma gondii thioredoxin reductase 0.0104 0.0252 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0061 0.235
Schistosoma mansoni hypothetical protein 0.0041 0.0078 0.0394
Leishmania major ferredoxin 2fe-2s-like protein 0.0028 0.0042 0.1674
Onchocerca volvulus 0.0036 0.0065 0.1038
Trypanosoma cruzi iron superoxide dismutase A, mitochondrial 0.0067 0.015 0.5943
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0019 0.0664
Plasmodium vivax glutathione reductase, putative 0.0104 0.0252 1
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0022 0.015
Schistosoma mansoni jumonji domain containing protein 0.0063 0.0139 0.0721
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0045 0.0088 0.0992
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0045 0.0232
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0002 0.0051
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0417 0.111 0.2897
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0874 0.2365 1
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0024 0.0098
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0021 0.0023 0.0728
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0141 0.0925
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0106 0.4218
Schistosoma mansoni hypothetical protein 0.002 0.0021 0.009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0775 0.3275
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0061 0.2278
Plasmodium vivax superoxide dismutase [Fe], putative 0.0067 0.015 0.5862
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0076 0.083
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0019 0.0093
Echinococcus granulosus lamin 0.0027 0.004 0.0206
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0079
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0031 0.0052 0.1976
Schistosoma mansoni polycystin 1-related 0.002 0.0021 0.009
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0018 0.0069
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0022 0.0089
Echinococcus granulosus lamin dm0 0.0027 0.004 0.0206
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0021 0.0024 0.0922
Trypanosoma brucei Mitochondrial SSU ribosomal protein, putative 0.0017 0.0011 0.0368
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0116 0.0285 0.2271
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0065 0.2556
Brugia malayi jmjC domain containing protein 0.0017 0.0012 0.0061
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0114 0.0279 0.1178
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0068 0.0153 0.1778
Brugia malayi Doublecortin family protein 0.002 0.0021 0.0125
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0019 0.0078
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0099
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0065 0.0061
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0131 0.0857
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0038 0.007 0.047
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0019 0.0126
Schistosoma mansoni adrenodoxin 0.0028 0.0042 0.0203
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0005 0.0018
Trichomonas vaginalis superoxide dismutase, putative 0.0067 0.015 0.0632
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0417 0.111 0.2905
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0019 0.0108
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0068 0.0153 0.0647
Echinococcus multilocularis fructose bisphosphate aldolase class I 0.0092 0.0217 0.0912
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0144 0.0361 0.0944
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0045 0.0088 0.0373
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0141 0.0942
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0065 0.2556
Trypanosoma cruzi DNA repair protein, putative 0.0036 0.0064 0.2517
Schistosoma mansoni inositol monophosphatase 0.0045 0.0088 0.0444
Echinococcus multilocularis nuclear receptor nhr 48 0.0018 0.0015 0.0057
Trypanosoma cruzi superoxide dismutase, putative 0.0017 0.0011 0.0439
Brugia malayi MAP kinase sur-1 0.0051 0.0106 0.0695
Loa Loa (eye worm) hypothetical protein 0.0048 0.0097 0.0651
Brugia malayi beta-lactamase family protein 0.0036 0.0065 0.0418
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0065 0.2556
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0058 0.0386
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0065 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0038 0.007 0.0453
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.0136 0.057
Schistosoma mansoni hypothetical protein 0.0019 0.0018 0.007
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0065 0.0274
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0557 0.1495 1
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0058 0.2281
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0099
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0061 0.0252
Onchocerca volvulus 0.0018 0.0015 0.0233
Leishmania major importin beta-1 subunit, putative 0.0028 0.0043 0.1688
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0058 0.015
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0046 0.0092 0.0974
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0126 0.031 0.0305
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.007 0.0292
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0005 0.0167
Brugia malayi Superoxide dismutase, mitochondrial precursor, putative 0.0067 0.015 0.0986
Echinococcus multilocularis lamin dm0 0.0027 0.004 0.0163
Echinococcus granulosus lysine specific demethylase 5A 0.0067 0.015 0.0793
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.015 0.0778
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0021 0.0023 0.01
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0076 0.2956
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.0139 0.0584
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.0161 0.0834
Loa Loa (eye worm) hypothetical protein 0.0038 0.007 0.047
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.0046 0.0092 0.0241
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0045 0.0088 0.0592
Loa Loa (eye worm) hypothetical protein 0.0105 0.0254 0.1702
Trypanosoma cruzi superoxide dismutase, putative 0.0038 0.007 0.2768
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0019 0.0014
Echinococcus multilocularis pyruvate kinase 0.0034 0.0058 0.0238
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0047 0.0095 0.0636
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0035 0.0974
Echinococcus granulosus thioredoxin glutathione reductase 0.0105 0.0253 0.1344
Brugia malayi Importin beta-1 subunit 0.0035 0.0061 0.039
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0012 0.0039
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0139
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0015 0.0072
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0102 0.0522
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.007 0.0453
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0068 0.0153 0.0794
Echinococcus granulosus survival motor neuron protein 1 0.0494 0.1321 0.7033
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0028 0.0042 0.0676
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0046 0.0092 0.0619
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0068 0.0153 0.5998
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0065 0.2556
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0068 0.0153 0.6076
Loa Loa (eye worm) follicle stimulating hormone receptor 0.028 0.0733 0.4904
Brugia malayi hypothetical protein 0.0018 0.0015 0.0081
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0088 0.3425
Trichomonas vaginalis superoxide dismutase [mn], putative 0.0067 0.015 0.0632
Schistosoma mansoni ran 0.0026 0.0036 0.0166
Schistosoma mansoni single-minded 0.0049 0.01 0.051
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0143
Brugia malayi nuclear hormone receptor 0.0018 0.0015 0.0081
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0021 0.0087
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0065 0.0418
Onchocerca volvulus 0.0036 0.0065 0.1038
Entamoeba histolytica hypothetical protein 0.0036 0.0065 0.0611
Trichomonas vaginalis Ferredoxin 3 0.0028 0.0042 0.0178
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0167 0.0424 0.0419
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0075 0.007
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0065 0.0269
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0023 0.0029 0.0991
Trypanosoma brucei ISWI complex protein 0.0015 0.0008 0.0221
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0134 0.0689
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0021 0.0023 0.0049
Brugia malayi Rhodanese-like domain containing protein 0.0114 0.0279 0.1852
Brugia malayi Pre-SET motif family protein 0.0211 0.0544 0.3628
Brugia malayi hypothetical protein 0.0494 0.1321 0.8833
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.002 0.0021 0.0103
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0012 0.0079
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0156
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0076 0.0316
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0019 0.0074
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0435
Chlamydia trachomatis protoporphyrinogen oxidase 0.0021 0.0023 0.0207
Echinococcus multilocularis pyruvate kinase 0.0034 0.0058 0.0238
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0046 0.0092 0.336
Echinococcus multilocularis transcription factor eb 0.0116 0.0285 0.1199
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0101 0.0242 0.1602
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0065 0.0274
Loa Loa (eye worm) hypothetical protein 0.0494 0.1321 0.8835
Mycobacterium tuberculosis Conserved hypothetical protein 0.0046 0.0092 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0106 0.0544
Schistosoma mansoni nuclear receptor nhr-48 0.0018 0.0015 0.0055
Trypanosoma brucei iron superoxide dismutase C, mitochondrial 0.0038 0.007 0.2714
Trypanosoma cruzi superoxide dismutase, putative 0.0038 0.007 0.2768
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0065 0.2572
Schistosoma mansoni intermediate filament proteins 0.0027 0.004 0.019
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0047 0.0095 0.0636
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0134 0.0338
Mycobacterium leprae Probable superoxide dismutase SodA 0.0067 0.015 0.0392
Brugia malayi Cytochrome P450 family protein 0.0014 0.0005 0.0012
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0005 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0038 0.007 0.0453
Echinococcus granulosus tumor protein p63 0.0341 0.0901 0.4798
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.0065 0.2556
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0106 0.412
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0045 0.0088 0.3497
Echinococcus granulosus pyruvate kinase 0.0017 0.0013 0.0061
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0775 0.3275
Schistosoma mansoni superoxide dismutase [mn] 0.0067 0.015 0.0776
Onchocerca volvulus 0.002 0.0021 0.0337
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0035 0.121
Leishmania major hypothetical protein, conserved 0.0038 0.007 0.2776
Trypanosoma cruzi trypanothione reductase, putative 0.0104 0.0252 1
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0012 0.0039
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0019 0.0733
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0019 0.0074
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0024 0.003 0.0078
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0068 0.0153 0.6076
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.0017
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0065 0.2423
Loa Loa (eye worm) hypothetical protein 0.0038 0.007 0.047
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0028 0.0042 0.1613
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0156
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0068 0.0153 0.0794
Schistosoma mansoni lamin 0.0027 0.004 0.019
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0012 0.004
Onchocerca volvulus 0.0114 0.0279 0.447
Onchocerca volvulus 0.0038 0.007 0.1123
Onchocerca volvulus 0.0031 0.005 0.0798
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0015 0.0057
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0557 0.1495 0.6314
Loa Loa (eye worm) hypothetical protein 0.0114 0.0279 0.1866
Entamoeba histolytica rodhanase-like domain containing protein 0.0114 0.0279 0.3441
Schistosoma mansoni hypothetical protein 0.0019 0.0018 0.007
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0021 0.0084
Brugia malayi amine oxidase, flavin-containing family protein 0.0021 0.0023 0.0138
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0033 0.0153
Brugia malayi hypothetical protein 0.0021 0.0023 0.0138
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0435
Plasmodium falciparum superoxide dismutase [Fe] 0.0067 0.015 0.575
Schistosoma mansoni cpg binding protein 0.0035 0.0061 0.0299
Trichomonas vaginalis cdc25c, putative 0.0114 0.0279 0.1178
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0065 0.0337
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0114 0.0279 0.1178
Echinococcus multilocularis pyruvate kinase 0.0017 0.0013 0.0048
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0023 0.0019
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0045 0.0088 0.0373
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0134 0.5293
Toxoplasma gondii histone lysine-specific demethylase 0.0021 0.0023 0.0756
Schistosoma mansoni nuclear receptor 0.0018 0.0015 0.0055
Plasmodium falciparum glutathione reductase 0.0104 0.0252 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.004 0.0268
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0002 0.0003
Brugia malayi beta-lactamase family protein 0.0036 0.0065 0.0418
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0012 0.0039
Plasmodium vivax JmjC domain containing protein 0.0017 0.0012 0.0262
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0114 0.0279 0.1178
Mycobacterium ulcerans electron transfer protein FdxB 0.0028 0.0042 0.0099
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0126 0.031 0.0305
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0021 0.0023 0.0093
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0068 0.0153 0.1038
Trypanosoma cruzi Iron/manganese superoxide dismutases, C-terminal domain containing protein, putative 0.0017 0.0011 0.0439
Brugia malayi hypoxia-induced factor 1 0.0152 0.0382 0.2545
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0038 0.007 0.047
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0141 0.0728
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0664
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0435
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0015 0.0055
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0141 0.0728
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0167 0.0424 0.1099
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0038 0.007 0.0368
Brugia malayi Bromodomain containing protein 0.0078 0.0179 0.1178
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0058 0.2126
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.007 0.0453
Echinococcus multilocularis lamin 0.0027 0.004 0.0163
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0036 0.0064 0.2462
Trichomonas vaginalis aldehyde oxidase, putative 0.0874 0.2365 1
Echinococcus granulosus phd:f box containing protein 0.0017 0.0012 0.0055
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.1404 0.3818 1
Brugia malayi hypothetical protein 0.002 0.0021 0.0121
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0045 0.0088 0.0368
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0024 0.003 0.0184
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0036 0.1231
Onchocerca volvulus 0.0114 0.0279 0.447
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0045 0.0088 0.3449
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0035 0.1319
Schistosoma mansoni lipoxygenase 0.0085 0.02 0.1042
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0161 0.6376
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0028 0.0042 0.0174
Brugia malayi nuclear receptor NHR-67 0.0018 0.0015 0.0081
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0122 0.03 0.1264
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0023 0.091
Loa Loa (eye worm) hypothetical protein 0.0116 0.0283 0.1896
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0012 0.0454
Echinococcus granulosus dnaJ subfamily B 0.0494 0.1321 0.7036
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0139
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0018 0.0015 0.0233
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0775 0.3275
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0038 0.007 0.0368
Loa Loa (eye worm) doublecortin family protein 0.002 0.0021 0.0143
Trypanosoma cruzi ISWI complex protein 0.0015 0.0008 0.0292
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0046 0.0092 0.0601
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0092 0.0217 0.0912
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0033 0.0135
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0036 0.0239
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0114 0.0279 0.1178
Leishmania major protein kinase, putative 0.0013 0.0002 0.0051
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0092 0.0217 0.1135
Loa Loa (eye worm) hypothetical protein 0.0038 0.007 0.047
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0028 0.0042 0.1279
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0088 0.0365
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0139
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0021 0.0024 0.0922
Brugia malayi TAR-binding protein 0.0064 0.0141 0.0925
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0065 0.0269
Trypanosoma cruzi iron superoxide dismutase, putative 0.0067 0.015 0.5943
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0028 0.0042 0.0266
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0099 0.0237 0.0232
Toxoplasma gondii histone lysine methyltransferase SET1 0.0069 0.0155 0.6091
Brugia malayi Bromodomain containing protein 0.0039 0.0071 0.046
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0117 0.0616
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0046 0.0092 0.3661
Treponema pallidum recombinase A 0.0116 0.0285 0.2107
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0046 0.0092 0.3661
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0038 0.007 0.0292
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0117 0.06
Plasmodium falciparum fructose-bisphosphate aldolase 0.0092 0.0217 0.8543
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0117 0.06
Echinococcus multilocularis GPCR, family 2 0.0019 0.0018 0.0069
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0065 0.2572
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0068 0.0153 0.0647
Leishmania major cytochrome p450-like protein 0.0014 0.0005 0.0167
Mycobacterium ulcerans hypothetical protein 0.0036 0.0065 0.0159
Plasmodium vivax fructose 1,6-bisphosphate aldolase, putative 0.0092 0.0217 0.8581
Onchocerca volvulus 0.024 0.0624 1
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0024 0.0102
Brugia malayi MH2 domain containing protein 0.0129 0.0319 0.2119
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0579 0.1555 0.4066
Mycobacterium tuberculosis Conserved protein 0.0036 0.0065 0.0061
Mycobacterium ulcerans electron transfer protein 0.0028 0.0042 0.0099
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0058 0.0369
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0038 0.007 0.047
Echinococcus granulosus zinc finger protein 0.0022 0.0025 0.0126
Schistosoma mansoni hypothetical protein 0.0354 0.0936 0.4977
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0036 0.0221
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0092 0.0217 0.115
Trypanosoma brucei electron transfer protein, putative 0.0028 0.0042 0.1613
Plasmodium falciparum thioredoxin reductase 0.0036 0.0065 0.2202
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0664
Leishmania major protein kinase, putative 0.0013 0.0002 0.0051
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3356 0.9175 0.9175
Onchocerca volvulus 0.0027 0.004 0.0637
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0114 0.0279 0.1466
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0106 0.056
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0065 0.0208
Echinococcus granulosus ferredoxin 0.0028 0.0042 0.0219
Brugia malayi conserved hypotetical protein 0.0018 0.0015 0.0081
Schistosoma mansoni hypothetical protein 0.0354 0.0936 0.4977
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0023 0.091
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0021 0.0024 0.0139
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0042 0.1674
Plasmodium falciparum epoxide hydrolase 1 0.0038 0.007 0.2432
Leishmania major fructose-1,6-bisphosphate aldolase 0.0092 0.0217 0.8609
Trypanosoma brucei iron superoxide dismutase 0.0067 0.015 0.5913
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0038 0.007 0.047
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0065 0.2556
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0117 0.06
Brugia malayi CXXC zinc finger family protein 0.0035 0.0061 0.0387
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0092 0.0217 0.8609
Echinococcus granulosus abhydrolase domain containing protein 0.0038 0.007 0.0367
Loa Loa (eye worm) glutathione reductase 0.0104 0.0252 0.1686
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0117 0.0489
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0134 0.0129
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0002 0.0051
Trypanosoma brucei cytochrome P450, putative 0.0014 0.0005 0.0094
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0012 0.0292
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0028 0.0042 0.0099
Trypanosoma cruzi superoxide dismutase, putative 0.0038 0.007 0.2768
Onchocerca volvulus 0.002 0.0021 0.0337
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0014 0.0005 0.0167
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0018 0.01
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.0065 0.006
Mycobacterium leprae Probable lipase LipE 0.0036 0.0065 0.017
Plasmodium vivax importin-beta 2, putative 0.0035 0.0061 0.2254
Echinococcus granulosus intermediate filament protein 0.0027 0.004 0.0206
Treponema pallidum fructose-bisphosphate aldolase 0.0295 0.0775 0.6798
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0065 0.0274
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0068 0.0153 0.1009
Loa Loa (eye worm) MH2 domain-containing protein 0.0129 0.0319 0.2133
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0117 0.0616
Mycobacterium tuberculosis Probable dehydrogenase 0.0099 0.0237 0.0232
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.005 0.0206
Schistosoma mansoni lamin 0.0027 0.004 0.019
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0141 0.059
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0664
Schistosoma mansoni rab6-interacting 0.002 0.0021 0.009
Brugia malayi RNA, U transporter 1 0.0099 0.0237 0.1571
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0122 0.03 0.1594
Schistosoma mansoni RAR-like nuclear receptor 0.0038 0.007 0.0351
Leishmania major iron superoxide dismutase, putative 0.0067 0.015 0.5943
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.015 0.0778
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.007 0.0453
Toxoplasma gondii ABC1 family protein 0.0036 0.0065 0.2446
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0046 0.0092 0.0231
Plasmodium falciparum pyruvate kinase 0.0034 0.0058 0.1914
Leishmania major iron superoxide dismutase, putative 0.0067 0.015 0.5943
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0038 0.007 0.0368
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0099
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0012 0.0044
Brugia malayi hypothetical protein 0.0025 0.0035 0.0217
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0024 0.0145
Loa Loa (eye worm) intermediate filament protein 0.0027 0.004 0.0268
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0012 0.0039
Echinococcus granulosus GPCR family 2 0.0019 0.0018 0.0087
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0106 0.4175
Mycobacterium ulcerans lipase LipD 0.0036 0.0065 0.0159
Plasmodium falciparum thioredoxin reductase 0.0104 0.0252 1
Leishmania major hypothetical protein, conserved 0.0017 0.0012 0.0454
Trichomonas vaginalis superoxide dismutase, putative 0.0067 0.015 0.0632
Schistosoma mansoni hypothetical protein 0.0019 0.0018 0.007
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0018 0.0015 0.0233
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0092 0.0217 0.8586
Leishmania major cytochrome p450-like protein 0.0014 0.0005 0.0167
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0088 0.3473
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.003 0.0145
Brugia malayi photoreceptor-specific nuclear receptor 0.0038 0.007 0.0453
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0412 0.1097 0.2864
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0088 0.0218
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0167 0.0424 0.1099
Brugia malayi nuclear hormone receptor 0.0038 0.007 0.0453
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0065 0.0415
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0002 0.0003
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0018 0.0087
Schistosoma mansoni zinc finger protein 0.0015 0.0008 0.0017
Brugia malayi fructose-bisphosphate aldolase 2 0.0092 0.0217 0.1436
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0076 0.3008
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0092 0.0217 0.115
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0259 0.0677 0.1763
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.0161 0.1059
Brugia malayi hypothetical protein 0.002 0.0021 0.0125
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0099
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0002 0.0051
Echinococcus granulosus pyruvate kinase 0.0034 0.0058 0.03
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0092 0.0217 0.0912
Mycobacterium tuberculosis Conserved protein 0.0036 0.0065 0.0061
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0126
Onchocerca volvulus 0.0028 0.0042 0.0676
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0134 0.0705
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.0161 0.0674
Brugia malayi nuclear receptor RXR 0.0018 0.0015 0.0081
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0268
Loa Loa (eye worm) hypothetical protein 0.006 0.0131 0.0873
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0005 0.0167
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0036 0.1258
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0088 0.037
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0068 0.0153 0.6047
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0076 0.0398
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0068 0.0153 0.1379
Schistosoma mansoni hypothetical protein 0.0372 0.0986 0.5239
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0018 0.0015 0.0081
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0664
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0023 0.0117
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0018 0.0015 0.0057
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0012 0.0079
Brugia malayi glutathione reductase 0.0104 0.0252 0.1671
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0068 0.0153 0.6076
Schistosoma mansoni steroid hormone receptor ad4bp 0.0038 0.007 0.0351
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0076 0.0757
Loa Loa (eye worm) hypothetical protein 0.0312 0.0821 0.5496
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0002 0.0013
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0018 0.0015 0.0099
Echinococcus granulosus RUN 0.002 0.0021 0.0106
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0046 0.0092 0.3554
Echinococcus multilocularis pyruvate kinase 0.0027 0.0038 0.0156
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0065 0.0272
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.007 0.0368
Loa Loa (eye worm) hypothetical protein 0.0038 0.007 0.047
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0013 0.0332
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0058 0.0053
Echinococcus granulosus bloom syndrome protein 0.0022 0.0024 0.0123
Trichomonas vaginalis ran, putative 0.0026 0.0036 0.0149
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0012 0.0039
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0021 0.065
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0038 0.007 0.0453
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0028 0.0042 0.038
Schistosoma mansoni pyruvate kinase 0.0034 0.0058 0.0284
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0058 0.0921
Brugia malayi ecdysteroid receptor 0.0038 0.007 0.0453
Loa Loa (eye worm) DR-78 0.0018 0.0015 0.0099
Echinococcus multilocularis ferredoxin adrenodoxin 0.0028 0.0042 0.0174
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0035 0.1237
Mycobacterium ulcerans beta-lactamase 0.0036 0.0065 0.0159
Loa Loa (eye worm) hydrolase 0.0038 0.007 0.047
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0065 0.0338
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0065 0.0323
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0035 0.0974
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.0065 0.2556
Schistosoma mansoni amine oxidase 0.0021 0.0023 0.01
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0038 0.007 0.0351
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0017 0.0229
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.007 0.0351
Brugia malayi nuclear hormone receptor family member nhr-6 0.0018 0.0015 0.0081
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0058 0.0386
Brugia malayi PHD-finger family protein 0.0027 0.004 0.0248
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0088 0.3473
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0068 0.0153 0.1778
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0775 0.3275
Trichomonas vaginalis set domain proteins, putative 0.024 0.0624 0.2635
Entamoeba histolytica Ran family GTPase 0.0026 0.0036 0.0223
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0076 0.0491
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0117 0.0489
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0435
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0076 0.032
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0038 0.007 0.0453
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0012 0.0055
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0068 0.0153 0.1778
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0097 0.0496
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0019 0.0037
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0021 0.0121
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0046 0.0092 0.0088
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0019 0.0037
Mycobacterium ulcerans recombinase A 0.0116 0.0285 0.0735
Echinococcus granulosus snurportin 1 0.0372 0.0986 0.5247
Plasmodium falciparum protoporphyrinogen oxidase 0.0021 0.0023 0.0478
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0775 0.3275
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.002 0.0021 0.0087
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0024 0.003 0.0126
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0131 0.0873
Chlamydia trachomatis replicative DNA helicase 0.0417 0.111 1
Loa Loa (eye worm) hypothetical protein 0.0165 0.0417 0.2793
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0038 0.007 0.0292
Onchocerca volvulus 0.0114 0.0279 0.447
Echinococcus granulosus cpg binding protein 0.0039 0.0071 0.0372
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0038 0.007 0.0292
Echinococcus granulosus manganese superoxide dismutase 0.0067 0.015 0.0792
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0106 0.0712
Leishmania major GTP-binding protein, putative 0.0026 0.0036 0.1403
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0068 0.0153 0.0794
Echinococcus granulosus dna polymerase eta 0.0019 0.0019 0.0093
Leishmania major UDP-galactopyranose mutase 0.0021 0.0023 0.091
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0014 0.0005 0.0094
Trichomonas vaginalis iron superoxide dismutase A, putative 0.0067 0.015 0.0632
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0065 0.2556
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0116 0.0283 0.1896
Leishmania major hypothetical protein, conserved 0.0015 0.0008 0.0292
Toxoplasma gondii superoxide dismutase SOD3 0.0067 0.015 0.5874
Chlamydia trachomatis recombinase RecA 0.0116 0.0285 0.2565
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0027 0.0038 0.0238
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0015 0.0057
Loa Loa (eye worm) hypoxia-induced factor 1 0.0152 0.0382 0.2558
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0099
Plasmodium falciparum ferredoxin, putative 0.0028 0.0042 0.1279
Leishmania major hypothetical protein, conserved 0.0036 0.0065 0.2572
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.0065 0.0158
Loa Loa (eye worm) hypothetical protein 0.0027 0.0039 0.0259
Echinococcus granulosus single minded 2 0.0036 0.0065 0.034
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0038 0.007 0.1123
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0435
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0021 0.0023 0.006
Loa Loa (eye worm) hypothetical protein 0.0038 0.007 0.047
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0068 0.0153 0.0647
Trypanosoma brucei fructose-bisphosphate aldolase, glycosomal, putative 0.0092 0.0217 0.8599
Loa Loa (eye worm) hypothetical protein 0.0045 0.0089 0.0595
Onchocerca volvulus Superoxide dismutase [Mn], mitochondrial homolog 0.0067 0.015 0.2399
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0141 0.0728
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0106 0.0449
Entamoeba histolytica hypothetical protein 0.0036 0.0065 0.0611
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0099
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0012 0.0055
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.0161 0.085
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0417 0.111 1
Mycobacterium ulcerans oxidoreductase 0.0021 0.0023 0.0049
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0114 0.0279 0.1178
Trypanosoma brucei unspecified product 0.0019 0.0019 0.0664
Onchocerca volvulus Superoxide dismutase [Mn], mitochondrial homolog 0.0046 0.0091 0.1459
Loa Loa (eye worm) cytochrome P450 0.0014 0.0005 0.003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0088 0.037
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0099
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.0161 0.1076
Loa Loa (eye worm) fructose-bisphosphate aldolase 1 0.0092 0.0217 0.1452
Loa Loa (eye worm) fructose-bisphosphate aldolase 2 0.0092 0.0217 0.1452
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0099
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0038 0.007 0.047
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0106 0.123
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0024 0.0102
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0065 0.0061
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0046 0.0092 0.3661
Chlamydia trachomatis pyruvate kinase 0.0034 0.0058 0.0517
Onchocerca volvulus 0.0036 0.0065 0.1038
Onchocerca volvulus 0.0021 0.0023 0.0368
Mycobacterium tuberculosis Probable oxidoreductase 0.0028 0.0042 0.0038
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0068 0.0153 0.6047
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0015 0.0081
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0036 0.0065 0.058
Brugia malayi Inositol-1 0.0045 0.0088 0.057
Echinococcus granulosus m phase inducer phosphatasecdc25 0.0114 0.0279 0.148
Echinococcus multilocularis microtubule associated protein 2 0.0697 0.1877 0.7931
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0065 0.2407
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0065 0.2556
Brugia malayi hypothetical protein 0.002 0.0021 0.0121
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0014 0.0095
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0018 0.0015 0.0055
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.0161 0.1878
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0019 0.0076
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0088 0.0424
Echinococcus granulosus importin subunit beta 1 0.0035 0.0061 0.0317
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.007 0.0453
Schistosoma mansoni hypothetical protein 0.0494 0.1321 0.7031
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0012 0.0044
Trypanosoma cruzi adrenodoxin precursor, putative 0.0028 0.0042 0.1674
Echinococcus multilocularis pyruvate kinase 0.0017 0.0013 0.0048
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0065 0.0061
Brugia malayi Muscleblind-like protein 0.0312 0.0821 0.5487
Loa Loa (eye worm) CYP4Cod1 0.0014 0.0005 0.003
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0076 0.0316
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0078 0.0326
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0065 0.0418
Loa Loa (eye worm) nuclear receptor NHR-67 0.0018 0.0015 0.0099
Schistosoma mansoni DNA polymerase eta 0.0019 0.0019 0.0076
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0021 0.0024 0.0922
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0068 0.0153 0.0848
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0015 0.0081
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0295 0.0776 0.2022
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0021 0.0084
Loa Loa (eye worm) twinkle helicase 0.0119 0.0292 0.1955
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0065 0.2501
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0099
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0012 0.0292
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0028 0.0042 0.0038
Echinococcus granulosus geminin 0.0354 0.0936 0.4985
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0019 0.0014
Echinococcus granulosus FTZ F1 alpha 0.0038 0.007 0.0368
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0156
Brugia malayi RNA binding protein 0.0064 0.0141 0.0925
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0012 0.0044
Loa Loa (eye worm) hypothetical protein 0.0038 0.007 0.047
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0156
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0058 0.0921
Brugia malayi jmjC domain containing protein 0.0067 0.015 0.0988
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0279 0.073 0.0726
Entamoeba histolytica hypothetical protein 0.0036 0.0065 0.0611
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0065 0.0159
Echinococcus granulosus dna polymerase kappa 0.0019 0.0019 0.0093
Brugia malayi PAS domain containing protein 0.0049 0.01 0.0653
Trichomonas vaginalis superoxide dismutase [fe], putative 0.0067 0.015 0.0632
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0005 0.0167
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.0065 0.0158
Entamoeba histolytica iron-containing superoxide dismutase 0.0067 0.015 0.1734
Echinococcus multilocularis cpg binding protein 0.0039 0.0071 0.0295
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0068 0.0153 0.081
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0116 0.0285 0.0745
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0099 0.0237 0.0232
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0106 0.0449
Loa Loa (eye worm) hypothetical protein 0.0114 0.0279 0.1866
Schistosoma mansoni bromodomain containing protein 0.0066 0.0146 0.0756
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0068 0.0153 0.6076
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0046 0.0092 0.3614
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0664
Echinococcus multilocularis dna polymerase eta 0.0019 0.0019 0.0074
Loa Loa (eye worm) hypothetical protein 0.0034 0.0058 0.0386
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.03 0.0788 0.2054
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0106 0.0444
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0134 0.0689
Mycobacterium ulcerans oxidoreductase 0.0028 0.0042 0.0099
Brugia malayi intermediate filament protein 0.0027 0.004 0.025
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0141 0.0942
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0021 0.0106
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0046 0.0092 0.0486
Echinococcus granulosus muscleblind protein 0.0312 0.0821 0.4372
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0012 0.0044
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.0139 0.0584
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0012 0.0454
Mycobacterium tuberculosis Possible oxidoreductase 0.0021 0.0023 0.0019
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0106 0.0449
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.007 0.0453
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0065 0.2556
Onchocerca volvulus 0.0018 0.0015 0.0233
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0038 0.007 0.0453
Leishmania major pyruvate kinase 0.0034 0.0058 0.2281
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0156
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0012 0.0383
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0065 0.0323
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0065 0.2556
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0161 0.6376
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0117 0.0765
Schistosoma mansoni loxhd1 0.002 0.0021 0.009
Mycobacterium ulcerans superoxide dismutase [Fe] SodA 0.0067 0.015 0.0381
Brugia malayi hydrolase, alpha/beta fold family protein 0.0038 0.007 0.0452
Trypanosoma cruzi DNA repair protein, putative 0.0036 0.0064 0.2517
Entamoeba histolytica hypothetical protein 0.0036 0.0065 0.0611
Brugia malayi nuclear receptor NHR-88 0.0018 0.0015 0.0081
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0068 0.0153 0.601
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0058 0.0921
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0035 0.1383
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0134 0.0338
Leishmania major iron superoxide dismutase 0.0067 0.015 0.5943
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.0161 0.6376
Brugia malayi nuclear receptor NHR-88 0.0038 0.007 0.0453
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0058 0.0139
Loa Loa (eye worm) inositol-1 0.0045 0.0088 0.0587
Echinococcus granulosus tar DNA binding protein 0.0064 0.0141 0.0743
Entamoeba histolytica rodhanase-like domain containing protein 0.0114 0.0279 0.3441
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0088 0.046
Treponema pallidum hypothetical protein 0.0117 0.0287 0.2124
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0099
Echinococcus multilocularis survival motor neuron protein 1 0.0494 0.1321 0.5578
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0018 0.0015 0.0057
Brugia malayi orphan nuclear receptor NR2E1 0.0018 0.0015 0.0081
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0038 0.007 0.0368
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.015 0.1005
Giardia lamblia [2Fe-2S] ferredoxin 0.0028 0.0042 0.039
Mycobacterium leprae putative cytochrome p450 0.0014 0.0005 0.0011
Entamoeba histolytica rodhanase-like domain containing protein 0.0114 0.0279 0.3441
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0038 0.007 0.0351
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0078 0.0506
Brugia malayi hypothetical protein 0.002 0.0021 0.0125
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0126 0.031 0.0811
Trypanosoma cruzi iron superoxide dismutase A, mitochondrial 0.0067 0.015 0.5943
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0036 0.0301
Trypanosoma cruzi iron superoxide dismutase, putative 0.0067 0.015 0.5943
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0045 0.0088 0.0464
Mycobacterium ulcerans oxidoreductase 0.0028 0.0042 0.0099
Echinococcus multilocularis geminin 0.0354 0.0936 0.3954
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0046 0.0092 0.047
Loa Loa (eye worm) hypothetical protein 0.0038 0.007 0.047
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1358 0.3691 0.3688
Loa Loa (eye worm) RNA binding protein 0.0064 0.0141 0.0942
Trichomonas vaginalis Ferredoxin 1 0.0028 0.0042 0.0178
Schistosoma mansoni pyruvate kinase 0.0034 0.0058 0.0284
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.002 0.0021 0.0082
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Trichomonas vaginalis Ferredoxin 4 0.0028 0.0042 0.0178
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.0136 0.0718
Onchocerca volvulus 0.0037 0.0067 0.1063
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0028 0.0042 0.1674
Echinococcus multilocularis abhydrolase domain containing protein 0.0038 0.007 0.0291
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0139
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0068 0.0153 0.6076
Toxoplasma gondii fructose-bisphosphate aldolase, putative 0.0092 0.0217 0.8586
Mycobacterium leprae Conserved hypothetical protein 0.0014 0.0005 0.0011
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0068 0.0153 0.6076
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.0775 0.3275
Giardia lamblia Fructose-bisphosphate aldolase 0.0295 0.0775 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0065 0.2556
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0058 0.0386
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0065 0.2202
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0117 0.0782
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0065 0.0435
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0144 0.0361 0.0356
Loa Loa (eye worm) hypothetical protein 0.004 0.0076 0.0509
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0295 0.0775 1
Giardia lamblia Pyruvate kinase 0.0034 0.0058 0.059
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0013 0.006
Brugia malayi ecdysone receptor 0.0018 0.0015 0.0081
Treponema pallidum quinoline 2-oxidoreductase 0.0139 0.0346 0.2696
Schistosoma mansoni Replicative DNA helicase 0.0417 0.111 0.5901
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0021 0.0024 0.0922
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0076 0.0382
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.1321 0.558
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0019 0.0664
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0045 0.0088 0.0592
Echinococcus granulosus pyruvate kinase 0.0017 0.0013 0.0061
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0065 0.0321
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0664
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.003 0.0199
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0156
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0019 0.0733
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0088 0.037
Mycobacterium leprae Conserved hypothetical protein 0.1229 0.3339 0.8744
Plasmodium vivax SET domain protein, putative 0.0031 0.005 0.1816
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0875 0.2366 1
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0013 0.0303
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0024 0.003 0.0026
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0019 0.0078
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0068 0.0153 0.6076
Brugia malayi jmjC domain containing protein 0.0017 0.0012 0.0061
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0038 0.007 0.0368
Loa Loa (eye worm) hypothetical protein 0.0045 0.0088 0.0592
Toxoplasma gondii ferredoxin, putative 0.0028 0.0042 0.1533
Leishmania major DNA polymerase eta, putative 0.0019 0.0019 0.0733
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0021 0.0084
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0036 0.0995
Schistosoma mansoni zinc finger protein 0.0022 0.0025 0.0109
Echinococcus multilocularis protoporphyrinogen oxidase 0.0021 0.0023 0.0093
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0036 0.134
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0106 0.0444
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0068 0.0153 0.1843
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0065 0.0272
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0019 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0019 0.0664
Trypanosoma brucei superoxide dismutase, putative 0.0038 0.007 0.2714
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0076 0.0316
Chlamydia trachomatis superoxide dismutase 0.0067 0.015 0.1348
Brugia malayi steroid hormone receptor 0.0038 0.007 0.0453
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0028 0.0042 0.0038
Echinococcus multilocularis manganese superoxide dismutase 0.0067 0.015 0.0628
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0068 0.0153 0.0647
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0058 0.2224
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0012 0.0079
Plasmodium vivax ferredoxin, putative 0.0028 0.0042 0.1508
Loa Loa (eye worm) hypothetical protein 0.0071 0.0161 0.1079
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.0544 0.3639
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0068 0.0153 0.6076
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0557 0.1495 0.7962
Brugia malayi tailless protein 0.0018 0.0015 0.0081

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.2311 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 0.8913 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.9953 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.2944 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 17.7828 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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