Detailed information for compound 1283957

Basic information

Technical information
  • TDR Targets ID: 1283957
  • Name: (4S,6S)-4-(4-bromophenyl)-6-[[4-(hydroxymethy l)phenyl]methoxy]-N-(phenylmethyl)-5,6-dihydr o-4H-pyran-2-carboxamide
  • MW: 508.404 | Formula: C27H26BrNO4
  • H donors: 2 H acceptors: 2 LogP: 4.91 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: OCc1ccc(cc1)CO[C@H]1OC(=C[C@H](C1)c1ccc(cc1)Br)C(=O)NCc1ccccc1
  • InChi: 1S/C27H26BrNO4/c28-24-12-10-22(11-13-24)23-14-25(27(31)29-16-19-4-2-1-3-5-19)33-26(15-23)32-18-21-8-6-20(17-30)7-9-21/h1-14,23,26,30H,15-18H2,(H,29,31)/t23-,26+/m1/s1
  • InChiKey: WIQXSJOTUJIZEA-BVAGGSTKSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (4S,6S)-N-(benzyl)-4-(4-bromophenyl)-6-(4-methylolbenzyl)oxy-5,6-dihydro-4H-pyran-2-carboxamide
  • SMR000442056
  • MLS000834556

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis cpg binding protein 0.006 0.0128 0.034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0092 0.0449
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0124 0.0357
Brugia malayi Cytochrome P450 family protein 0.0027 0.0038 0.011
Onchocerca volvulus 0.0253 0.0645 0.3181
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0029 0.0082
Echinococcus granulosus peroxidasin 0.004 0.0075 0.0197
Loa Loa (eye worm) hypothetical protein 0.0028 0.0043 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0066 0.0579
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0196 0.0577
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0026 0.0036 0.0093
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.0036 0.0093
Plasmodium vivax SET domain protein, putative 0.0098 0.0228 0.3528
Brugia malayi latrophilin 2 splice variant baaae 0.0685 0.1803 0.5187
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0016 0.0009 0.0016
Trypanosoma brucei trypanothione reductase 0.0038 0.0067 0.1023
Treponema pallidum replicative DNA helicase (dnaB) 0.0427 0.1111 1
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0005 0.0015
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0056 0.0271
Loa Loa (eye worm) major facilitator superfamily transporter 0.0052 0.0107 0.0306
Echinococcus multilocularis g protein coupled receptor 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Leishmania major cytochrome p450-like protein 0.0027 0.0038 0.0574
Echinococcus multilocularis serotonin receptor 0.0144 0.0351 0.0939
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0008 0.0017
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.0317 0.0816 0.2349
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0023 0.0339
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0161 0.0427
Entamoeba histolytica hypothetical protein 0.0016 0.0009 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0048 0.0096 0.0276
Echinococcus multilocularis sex peptide receptor 0.0026 0.0036 0.0093
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0014 0.0004 0.0007
Echinococcus granulosus cytochrome P450 2K1 0.0027 0.0038 0.0099
Mycobacterium ulcerans recombinase A 0.0119 0.0286 0.2566
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Loa Loa (eye worm) hypothetical protein 0.1309 0.3476 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0093 0.1418
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0005 0.0015
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0015 0.0005 0.0036
Schistosoma mansoni lamin 0.003 0.0046 0.012
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0023 0.0028 0.0079
Echinococcus multilocularis fmrfamide receptor 0.0026 0.0036 0.0093
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0027 0.0038 0.0038
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0093 0.0245
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0048 0.0725
Onchocerca volvulus Peroxidasin homolog 0.004 0.0075 0.0352
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0068 0.0177
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0001 0.001
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0119 0.0286 0.0846
Echinococcus multilocularis multidrug resistance associated protein 7 0.0016 0.0009 0.0019
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0163 0.1457
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0515 0.2547
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0025 0.1818
Giardia lamblia Multidrug resistance-associated protein 1 0.0016 0.0009 0.0086
Loa Loa (eye worm) hypothetical protein 0.0048 0.0096 0.0276
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0016 0.0009 0.0111
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0005 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0027 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Echinococcus granulosus histone acetyltransferase KAT2B 0.0156 0.0384 0.1025
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0026 0.0036 0.0093
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0079
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0001 0.0047
Trypanosoma brucei antigen, putative 0.0021 0.0023 0.0339
Echinococcus multilocularis neuropeptide receptor 0.0026 0.0036 0.0093
Brugia malayi RNA, U transporter 1 0.0176 0.0438 0.1261
Echinococcus granulosus pyruvate kinase 0.0017 0.0012 0.0029
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0009 0.0021
Toxoplasma gondii facilitative glucose transporter GT1 0.0052 0.0107 0.1635
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Brugia malayi mbt repeat family protein 0.0058 0.0121 0.0347
Plasmodium falciparum glutathione reductase 0.0013 0.0001 0.0047
Leishmania major hypothetical protein, conserved 0.0253 0.0645 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0597 0.1567 0.4508
Brugia malayi mothers against decapentaplegic homolog 3 0.0018 0.0015 0.0043
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0048 0.0096 0.0276
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Trichomonas vaginalis D-aminoacylase, putative 0.0253 0.0645 0.3191
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.0174 0.0464
Brugia malayi larval opioid receptor 0.0026 0.0036 0.0103
Brugia malayi bHLH-PAS transcription factor 0.004 0.0073 0.021
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0105 0.0249 0.0664
Echinococcus granulosus calpain A 0.0075 0.0167 0.0444
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0052 0.0107 0.0282
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0069 0.018
Schistosoma mansoni multidrug resistance protein 0.0016 0.0009 0.0019
Brugia malayi Tachykinin-like peptides receptor 99D 0.0026 0.0036 0.0103
Brugia malayi hypothetical protein 0.0052 0.0107 0.0306
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0026 0.0036 0.0103
Mycobacterium leprae Conserved hypothetical protein 0.1258 0.334 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.0036 0.0093
Toxoplasma gondii thioredoxin reductase 0.0038 0.0067 0.1023
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.0803 0.2309
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.028 0.0717 0.1918
Loa Loa (eye worm) calpain 5 0.0021 0.0023 0.0066
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0079
Schistosoma mansoni transient receptor potential channel 4 0.0117 0.0281 0.0749
Brugia malayi Cytochrome P450 family protein 0.015 0.0369 0.1062
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0141 0.2169
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0075 0.0167 0.0444
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0048 0.0096 0.0254
Brugia malayi MH2 domain containing protein 0.0018 0.0015 0.0043
Brugia malayi PAS domain containing protein 0.0054 0.011 0.0317
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0017 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0048 0.0096 0.0276
Schistosoma mansoni steroid hormone receptor ad4bp 0.0048 0.0096 0.0254
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0015 0.0005 0.0036
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0016 0.0009 0.0009
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0073 0.0191
Schistosoma mansoni biogenic amine (5HT) receptor 0.039 0.1011 0.2707
Toxoplasma gondii HEAT repeat-containing protein 0.0062 0.0132 0.2035
Schistosoma mansoni aryl hydrocarbon receptor 0.0054 0.011 0.0293
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0028 0.0071
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0317 0.0816 0.2186
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Brugia malayi Importin beta-1 subunit 0.0062 0.0132 0.0381
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0068 0.0148 0.132
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0035 0.009
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0075 0.0167 0.0444
Onchocerca volvulus 0.0026 0.0036 0.0159
Giardia lamblia Pyruvate kinase 0.0017 0.0012 0.0132
Mycobacterium tuberculosis Conserved protein 0.0253 0.0645 0.0645
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Schistosoma mansoni neuropeptide f receptor 76f 0.0026 0.0036 0.0093
Schistosoma mansoni multidrug resistance protein 0.0016 0.0009 0.0019
Schistosoma mansoni Replicative DNA helicase 0.0427 0.1111 0.2974
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0093 0.1426
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0017 0.0049
Echinococcus granulosus dnaJ subfamily B 0.0812 0.2144 0.5747
Brugia malayi jmjC domain containing protein 0.0093 0.0217 0.0623
Trypanosoma cruzi hypothetical protein, conserved 0.0253 0.0645 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0005 0.001
Trichomonas vaginalis set domain proteins, putative 0.0766 0.2019 1
Echinococcus granulosus neuropeptides capa receptor 0.0026 0.0036 0.0093
Echinococcus granulosus 7TM GPCR rhodopsin 0.0026 0.0036 0.0093
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0092 0.1402
Echinococcus granulosus nuclear factor of activated T cells 5 0.0081 0.0184 0.0491
Brugia malayi Death domain containing protein 0.0016 0.0009 0.0026
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0068 0.0148 0.132
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0141 0.2169
Brugia malayi hypothetical protein 0.0026 0.0036 0.0103
Onchocerca volvulus Dual oxidase homolog 0.004 0.0075 0.0352
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0034 0.0059 0.0889
Echinococcus multilocularis solute carrier family 22 0.0052 0.0107 0.0282
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0005 0.0005
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0125 0.0359
Schistosoma mansoni zinc finger protein 0.0023 0.0028 0.0071
Leishmania major pyruvate kinase 0.0033 0.0056 0.0845
Echinococcus multilocularis peroxidasin 0.004 0.0075 0.0197
Echinococcus granulosus transient receptor potential gamma protein 0.0117 0.0281 0.0749
Brugia malayi TAR-binding protein 0.0124 0.03 0.0863
Echinococcus multilocularis solute carrier family 22 0.0052 0.0107 0.0282
Schistosoma mansoni lamin 0.003 0.0046 0.012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0066 0.0188
Trypanosoma brucei sugar transporter, putative 0.0052 0.0107 0.1635
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0048 0.0096 0.0254
Entamoeba histolytica ATP-binding cassette protein, putative 0.0016 0.0009 0.0038
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0033 0.0056 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0107 0.0523
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0075 0.0215
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0015 0.0005 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0048 0.0096 0.0276
Loa Loa (eye worm) hypothetical protein 0.0062 0.0132 0.0381
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0026 0.0036 0.0103
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0003 0.0005
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0043 0.0644
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.0121 0.032
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0068 0.0148 0.0148
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0427 0.1111 1
Echinococcus multilocularis snurportin 1 0.0661 0.1738 0.4656
Trypanosoma brucei glucose transporter, putative 0.0052 0.0107 0.1635
Brugia malayi Uncoordinated protein 44 0.0016 0.0009 0.0026
Treponema pallidum recombinase A 0.0119 0.0286 0.2566
Trypanosoma brucei glucose transporter 2A 0.0052 0.0107 0.1635
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0027 0.0038 0.0038
Trichomonas vaginalis D-aminoacylase, putative 0.0253 0.0645 0.3191
Schistosoma mansoni Smad4 0.0018 0.0015 0.0037
Brugia malayi beta-lactamase family protein 0.0253 0.0645 0.1856
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0008 0.0017
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0009 0.0026
Brugia malayi Blistered cuticle protein 3 0.004 0.0075 0.0215
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0068 0.0148 0.0425
Schistosoma mansoni smad1 5 8 and 0.0041 0.0076 0.0199
Leishmania major importin beta-1 subunit, putative 0.005 0.0101 0.1548
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0053 0.0107 0.0954
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0008 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0048 0.0096 0.0276
Trypanosoma brucei THT1 - hexose transporter, putative 0.0052 0.0107 0.1635
Schistosoma mansoni Mername-AA248 (C02 family) 0.0021 0.0023 0.0059
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.006 0.006
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0027 0.0038 0.0038
Trypanosoma brucei THT1 - hexose transporter, putative 0.0052 0.0107 0.1635
Loa Loa (eye worm) hypothetical protein 0.0117 0.0281 0.0807
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0017 0.0246
Brugia malayi Thioredoxin reductase 0.0038 0.0067 0.0193
Schistosoma mansoni biogenic amine receptor 0.0026 0.0036 0.0093
Loa Loa (eye worm) cytochrome P450 0.0027 0.0038 0.011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0027 0.0038 0.0574
Echinococcus granulosus alpha 1A adrenergic receptor 0.0026 0.0036 0.0093
Echinococcus granulosus neuropeptide receptor 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.0253 0.0645 0.1856
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0015 0.0005 0.0036
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0163 0.1457
Mycobacterium ulcerans acetyl-CoA synthetase 0.0015 0.0005 0.0036
Brugia malayi hypothetical protein 0.0026 0.0036 0.0103
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0076 0.0358
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0028 0.0071
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0067 0.0193
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0052 0.0107 0.0282
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0023 0.0028 0.0071
Loa Loa (eye worm) hypothetical protein 0.005 0.01 0.0289
Echinococcus granulosus mothers against decapentaplegic 6 0.0018 0.0015 0.0037
Brugia malayi hypothetical protein 0.0026 0.0035 0.01
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0056 0.016
Brugia malayi Nuclear hormone receptor E75 0.0023 0.0028 0.0079
Brugia malayi beta-lactamase 0.0253 0.0645 0.1856
Trypanosoma cruzi hexose transporter 0.0052 0.0107 0.1635
Loa Loa (eye worm) acetyltransferase 0.016 0.0396 0.1138
Schistosoma mansoni hypothetical protein 0.0685 0.1803 0.4831
Brugia malayi MH1 domain containing protein 0.0022 0.0027 0.0077
Echinococcus multilocularis nuclear receptor nhr 48 0.0023 0.0028 0.0071
Echinococcus granulosus solute carrier family 22 0.0052 0.0107 0.0282
Brugia malayi multidrug resistance related protein 1 0.0016 0.0009 0.0024
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0141 0.2169
Brugia malayi mbt repeat family protein 0.0058 0.0121 0.0347
Brugia malayi G protein-coupled receptor F59B2.13 0.0026 0.0036 0.0103
Echinococcus multilocularis pyruvate kinase 0.0017 0.0012 0.0029
Echinococcus multilocularis calpain A 0.0075 0.0167 0.0444
Schistosoma mansoni ran 0.0022 0.0025 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0099 0.0881
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0099 0.1518
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0545 0.2693
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0056 0.0845
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0004 0.0014
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0014 0.0004 0.0011
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.0004 0.0039
Loa Loa (eye worm) G-protein coupled receptor 0.0026 0.0036 0.0103
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0081 0.0184 0.0491
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0099 0.1134
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.0175 0.0465
Trichomonas vaginalis sugar transport protein, putative 0.0052 0.0107 0.0523
Giardia lamblia Hexose transporter 0.0052 0.0107 0.1267
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0048 0.0096 0.0276
Leishmania major pentamidine resistance protein 1 0.0016 0.0009 0.0111
Echinococcus granulosus allatostatin A receptor 0.0026 0.0036 0.0093
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0047 0.0092 0.0242
Schistosoma mansoni peroxidasin 0.004 0.0075 0.0197
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0008 0.0017
Echinococcus granulosus neuropeptide FF receptor 2 0.0026 0.0036 0.0093
Brugia malayi Sugar transporter family protein 0.0052 0.0107 0.0306
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Brugia malayi nuclear hormone receptor family member nhr-6 0.0023 0.0028 0.0079
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.0028 0.0071
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0028 0.0071
Loa Loa (eye worm) TAR-binding protein 0.0124 0.03 0.0863
Brugia malayi N-terminal motif family protein 0.0199 0.0501 0.1441
Schistosoma mansoni cpg binding protein 0.006 0.0128 0.034
Trypanosoma brucei glucose transporter, putative 0.0052 0.0107 0.1635
Trypanosoma cruzi kinesin, putative 0.0021 0.0023 0.0339
Schistosoma mansoni biogenic amine receptor 0.0026 0.0036 0.0093
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0068 0.0148 0.0392
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0015
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0017 0.0246
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0075 0.0215
Echinococcus multilocularis neuropeptide Y receptor 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Toxoplasma gondii histone lysine methyltransferase SET1 0.0116 0.0276 0.4269
Trichomonas vaginalis importin beta-1, putative 0.005 0.0101 0.0495
Toxoplasma gondii NAC domain-containing protein 0.0039 0.007 0.1066
Schistosoma mansoni Smad4 0.0041 0.0076 0.0199
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.0036 0.0093
Echinococcus granulosus multidrug resistance associated protein 1 0.0016 0.0009 0.0019
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0017 0.0043
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0052 0.0107 0.1635
Schistosoma mansoni amine GPCR 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.0048 0.0096 0.0276
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0023 0.0339
Echinococcus granulosus snurportin 1 0.0661 0.1738 0.4656
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0098 0.0228 0.0608
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0027 0.0038 0.0038
Echinococcus granulosus importin subunit beta 1 0.0062 0.0132 0.0351
Brugia malayi calpain 5 0.0021 0.0023 0.0066
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0082 0.0929
Echinococcus granulosus mothers against decapentaplegic 5 0.0041 0.0076 0.0199
Trypanosoma brucei glucose transporter, putative 0.0052 0.0107 0.1635
Loa Loa (eye worm) hypothetical protein 0.0026 0.0035 0.01
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0048 0.0096 0.0254
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0163 0.2511
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0253 0.0645 0.1726
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0056 0.016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0228 0.0608
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0132 0.2035
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.0036 0.0093
Echinococcus multilocularis mitogen activated protein kinase 14 0.014 0.0342 0.0912
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.0028 0.0071
Loa Loa (eye worm) hypothetical protein 0.0044 0.0083 0.0239
Brugia malayi sulfakinin receptor protein 0.0026 0.0036 0.0103
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0004 0.0014
Echinococcus granulosus orexin receptor type 2 0.0026 0.0036 0.0093
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0005 0.0021
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0005 0.0063
Echinococcus multilocularis microtubule associated protein 2 0.0762 0.201 0.5385
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.007 0.1066
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Loa Loa (eye worm) hypothetical protein 0.0037 0.0066 0.0188
Echinococcus granulosus GPCR family 2 0.0317 0.0816 0.2186
Loa Loa (eye worm) MH1 domain-containing protein 0.0041 0.0076 0.0217
Loa Loa (eye worm) latrophilin receptor protein 2 0.0317 0.0816 0.2349
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0009 0.0026
Loa Loa (eye worm) MBCTL1 0.0066 0.0142 0.0409
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0017 0.0043
Echinococcus multilocularis chromobox protein 1 0.0068 0.0148 0.0393
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.001
Echinococcus multilocularis jun protein 0.0093 0.0215 0.0573
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0027 0.0038 0.0333
Mycobacterium tuberculosis Conserved protein 0.0253 0.0645 0.0645
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0095 0.0222 0.0222
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0099 0.1134
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0047 0.0092 0.0242
Brugia malayi hypothetical protein 0.0026 0.0036 0.0103
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0803 0.3971
Loa Loa (eye worm) hypoxia-induced factor 1 0.0166 0.0412 0.1186
Schistosoma mansoni nuclear receptor 0.0023 0.0028 0.0071
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0027 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0253 0.0645 0.1856
Brugia malayi SET domain containing protein 0.0016 0.0009 0.0026
Brugia malayi hypothetical protein 0.0072 0.0161 0.0462
Loa Loa (eye worm) hypothetical protein 0.0049 0.0099 0.0285
Brugia malayi cytochrome P450 0.0027 0.0038 0.011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0048 0.0096 0.0276
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0014
Brugia malayi Nuclear hormone receptor E75 0.0023 0.0028 0.0079
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0027 0.0038 0.0333
Trypanosoma cruzi polo-like protein kinase, putative 0.0105 0.0249 0.3844
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Mycobacterium leprae Conserved hypothetical protein 0.0027 0.0038 0.0103
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0027 0.0038 0.0574
Loa Loa (eye worm) hypothetical protein 0.0144 0.0351 0.1011
Loa Loa (eye worm) hypothetical protein 0.0047 0.0092 0.0263
Mycobacterium tuberculosis Probable lipase LipD 0.0253 0.0645 0.0645
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Schistosoma mansoni pyruvate kinase 0.0033 0.0056 0.0146
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0023 0.0059
Echinococcus multilocularis hypothetical protein 0.0021 0.0023 0.0059
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0047 0.0092 0.1043
Onchocerca volvulus 0.0026 0.0036 0.0159
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0068 0.0178
Trichomonas vaginalis glucose transporter, putative 0.0052 0.0107 0.0523
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0048 0.0096 0.0276
Brugia malayi Smad1 0.0041 0.0076 0.0217
Schistosoma mansoni neuropeptide receptor 0.0026 0.0036 0.0093
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.0028 0.0071
Schistosoma mansoni glucose transport protein 0.0052 0.0107 0.0282
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0098 0.0228 0.0608
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0066 0.1006
Echinococcus granulosus g-protein coupled receptor 0.0026 0.0036 0.0093
Echinococcus granulosus geminin 0.1404 0.3731 1
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0014 0.0004 0.0007
Loa Loa (eye worm) DR-78 0.0023 0.0028 0.0079
Leishmania major glucose transporter, lmgt2 0.0052 0.0107 0.1635
Echinococcus multilocularis importin subunit beta 1 0.0062 0.0132 0.0351
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0025 0.0071
Trichomonas vaginalis glucose transporter, putative 0.0052 0.0107 0.0523
Onchocerca volvulus 0.017 0.0422 0.2072
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0005 0.0005
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0003 0.0005
Schistosoma mansoni retinoic acid receptor RXR 0.0048 0.0096 0.0254
Plasmodium falciparum importin beta, putative 0.0062 0.0132 1
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0013 0.0001 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0027 0.0038 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0515 0.2547
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0027 0.0038 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0027 0.0038 0.0038
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0027 0.0038 0.0333
Trypanosoma brucei unspecified product 0.0013 0.0001 0.0002
Loa Loa (eye worm) sugar transporter 0.0052 0.0107 0.0306
Trypanosoma cruzi hexose transporter, putative 0.0052 0.0107 0.1635
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0023 0.0339
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0017 0.0246
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0079
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0092 0.1402
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0096 0.0276
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0016 0.0009 0.0024
Brugia malayi RNA recognition motif domain containing protein 0.0124 0.03 0.0863
Schistosoma mansoni multidrug resistance protein 0.0016 0.0009 0.0019
Onchocerca volvulus 0.0052 0.0107 0.051
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0038 0.0333
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0253 0.0645 0.0645
Leishmania major kinesin, putative 0.0021 0.0023 0.0339
Loa Loa (eye worm) hypothetical protein 0.0037 0.0066 0.0188
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0099 0.1134
Onchocerca volvulus 0.0052 0.0107 0.051
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Loa Loa (eye worm) twinkle helicase 0.0122 0.0293 0.0844
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0014 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0026 0.0035 0.01
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0056 0.0491
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0026 0.0036 0.0093
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.012 0.1836
Brugia malayi P38 map kinase family protein 2 0.014 0.0342 0.0982
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Loa Loa (eye worm) hypothetical protein 0.0253 0.0645 0.1856
Echinococcus multilocularis peregrin 0.0032 0.0053 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.0074 0.0164 0.0471
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0027 0.0038 0.0333
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0005 0.0015
Echinococcus granulosus intermediate filament protein 0.003 0.0046 0.012
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0096 0.0276
Onchocerca volvulus Chorion peroxidase homolog 0.004 0.0075 0.0352
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0093 0.0215 0.0573
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.014 0.0342 0.0982
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0099 0.0881
Schistosoma mansoni transient receptor potential channel 0.0078 0.0175 0.0465
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.0066 0.0579
Trypanosoma cruzi DNA repair protein, putative 0.0037 0.0065 0.0986
Brugia malayi RE15519p 0.0026 0.0036 0.0103
Schistosoma mansoni peroxidasin 0.004 0.0075 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.007 0.0341
Trichomonas vaginalis glucose transporter, putative 0.0052 0.0107 0.0523
Leishmania major DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0026 0.0035 0.009
Onchocerca volvulus 0.0052 0.0107 0.051
Echinococcus granulosus neuropeptides capa receptor 0.0026 0.0036 0.0093
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0027 0.0038 0.0333
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.0142 0.0378
Schistosoma mansoni hypothetical protein 0.0026 0.0036 0.0093
Loa Loa (eye worm) calpain family protein 1 0.005 0.01 0.0289
Echinococcus granulosus FTZ F1 alpha 0.0048 0.0096 0.0254
Leishmania major myo-inositol/proton symporter (MIT) 0.0052 0.0107 0.1635
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.014 0.0342 0.5285
Echinococcus granulosus microtubule associated protein 2 0.0762 0.201 0.5385
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0015 0.0005 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0249 0.1228
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.0028 0.0118
Schistosoma mansoni alpha-1 adrenergic receptor 0.0026 0.0036 0.0093
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0047 0.0092 0.1087
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0035 0.01
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0017 0.008
Brugia malayi hypothetical protein 0.003 0.0048 0.0138
Brugia malayi hypothetical protein 0.002 0.0019 0.0055
Schistosoma mansoni hypothetical protein 0.0052 0.0107 0.0282
Trypanosoma brucei glucose transporter, putative 0.0052 0.0107 0.1635
Brugia malayi hypothetical protein 0.0026 0.0036 0.0103
Giardia lamblia Pyruvate kinase 0.0033 0.0056 0.0655
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0068 0.0319
Schistosoma mansoni smad1 5 8 and 0.0041 0.0076 0.0199
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.012 0.1424
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0079
Loa Loa (eye worm) oxidoreductase 0.0015 0.0005 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0009 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0107 0.0523
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0132 0.2035
Schistosoma mansoni microtubule-associated protein tau 0.0762 0.201 0.5385
Echinococcus granulosus calpain 7 C02 family 0.0021 0.0023 0.0059
Giardia lamblia ABC transporter, putative 0.0016 0.0009 0.0086
Entamoeba histolytica ABC transporter, putative 0.0016 0.0009 0.0038
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.012 0.0587
Echinococcus multilocularis serotonin receptor 0.0144 0.0351 0.0939
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0017 0.0143
Schistosoma mansoni biogenic amine (5HT) receptor 0.0144 0.0351 0.0939
Onchocerca volvulus 0.0026 0.0036 0.0159
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0068 0.0178
Onchocerca volvulus 0.0052 0.0107 0.051
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0043 0.0111
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0008 0.0017
Loa Loa (eye worm) hypothetical protein 0.0048 0.0096 0.0276
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.0121 0.0347
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0005 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0048 0.0096 0.0276
Brugia malayi hypothetical protein 0.0026 0.0036 0.0103
Brugia malayi hypothetical protein 0.0026 0.0036 0.0103
Brugia malayi steroid hormone receptor 0.0048 0.0096 0.0276
Echinococcus multilocularis Smad4 0.0041 0.0076 0.0199
Onchocerca volvulus 0.005 0.01 0.0479
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.016 0.0396 0.1057
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.0175 0.0465
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.0004 0.0039
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.012 0.0344
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.028 0.0717 0.1918
Schistosoma mansoni hypothetical protein 0.0028 0.0043 0.0111
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0023 0.0067
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0048 0.0096 0.0254
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.0142 0.0378
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0021 0.0023 0.0339
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0068 0.0194
Loa Loa (eye worm) hypothetical protein 0.0048 0.0096 0.0276
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0027 0.0038 0.0333
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0096 0.0254
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0099 0.1518
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0026 0.0035 0.01
Loa Loa (eye worm) neuropeptide F receptor 0.0026 0.0036 0.0103
Brugia malayi RNA binding protein 0.0124 0.03 0.0863
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.014 0.0342 0.5285
Leishmania major p-glycoprotein e 0.0016 0.0009 0.0111
Schistosoma mansoni hypothetical protein 0.0317 0.0816 0.2186
Echinococcus multilocularis 0.0027 0.0038 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0001 0.0002
Echinococcus granulosus ecdysone induced protein 78C 0.0048 0.0096 0.0254
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0048 0.0096 0.0254
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0052 0.0107 0.0107
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0026 0.0036 0.0103
Loa Loa (eye worm) hypothetical protein 0.0048 0.0096 0.0276
Loa Loa (eye worm) hypothetical protein 0.0253 0.0645 0.1856
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0027 0.0038 0.0038
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0026 0.0036 0.0093
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0027 0.0038 0.0333
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0012 0.017
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0047 0.0092 0.0263
Echinococcus multilocularis g-protein coupled receptor 0.0026 0.0036 0.0093
Mycobacterium ulcerans beta-lactamase 0.0253 0.0645 0.5804
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0099 0.0285
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0048 0.0096 0.0254
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0323 0.0832 1
Brugia malayi GnHR receptor homolog 0.0026 0.0036 0.0103
Mycobacterium leprae Probable lipase LipE 0.0253 0.0645 0.1922
Echinococcus multilocularis dna polymerase eta 0.0019 0.0017 0.0043
Brugia malayi calpain 7 0.0021 0.0023 0.0066
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0196 0.0196
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0082 0.0973
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0099 0.0285
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0035 0.01
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Echinococcus multilocularis lamin dm0 0.003 0.0046 0.012
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0624 0.1639 0.4392
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0217 0.0577
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.028 0.0717 0.2062
Loa Loa (eye worm) hypothetical protein 0.0038 0.0068 0.0196
Schistosoma mansoni smad 0.0018 0.0015 0.0037
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0025 0.0362
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0023 0.0339
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0027 0.0038 0.0574
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0107 0.0523
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Schistosoma mansoni glucose transporter 0.0052 0.0107 0.0282
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.028 0.0717 0.1918
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Schistosoma mansoni chromobox protein 0.0068 0.0148 0.0393
Brugia malayi Sugar transporter family protein 0.0052 0.0107 0.0306
Echinococcus multilocularis neuropeptides capa receptor 0.0026 0.0036 0.0093
Echinococcus granulosus peptide allatostatin:somatostatin 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0077
Loa Loa (eye worm) hypothetical protein 0.0048 0.0096 0.0276
Echinococcus granulosus g protein coupled receptor 0.0026 0.0036 0.0093
Schistosoma mansoni tar DNA-binding protein 0.0124 0.03 0.0801
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.028 0.0717 0.2062
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.006 0.006
Brugia malayi Heterochromatin protein 1 0.0068 0.0148 0.0426
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Echinococcus granulosus tachykinin peptides receptor 99D 0.0026 0.0036 0.0093
Brugia malayi neuropeptide F receptor 0.0026 0.0036 0.0103
Schistosoma mansoni hydrolase 0.0042 0.0079 0.0207
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0026 0.0035 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0107 0.0523
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0227 0.0575 0.1538
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0052 0.0107 0.0282
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0037 0.0065 0.0986
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0052 0.0107 0.0949
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0047 0.0092 0.0242
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Mycobacterium tuberculosis Probable reductase 0.0086 0.0196 0.0196
Echinococcus granulosus single minded 2 0.004 0.0073 0.0192
Leishmania major ABC-thiol transporter 0.0016 0.0009 0.0111
Echinococcus granulosus peregrin 0.0032 0.0053 0.0139
Schistosoma mansoni multidrug resistance protein 0.0016 0.0009 0.0019
Trypanosoma brucei multidrug resistance protein E 0.0016 0.0009 0.0111
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0163 0.2511
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0048 0.0096 0.0276
Brugia malayi neuropeptide F receptor 0.0026 0.0036 0.0103
Brugia malayi Animal haem peroxidase family protein 0.004 0.0075 0.0215
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0025 0.0062
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0017 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0107 0.0523
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0052 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0011
Schistosoma mansoni cpg binding protein 0.0057 0.0119 0.0316
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0027 0.0038 0.0333
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0092 0.1402
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0148 0.0728
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0253 0.0645 0.1856
Trypanosoma cruzi multidrug resistance protein E, putative 0.0016 0.0009 0.0111
Leishmania major glucose transporter/membrane transporter D2, putative 0.0052 0.0107 0.1635
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Brugia malayi Cytochrome P450 family protein 0.0027 0.0038 0.011
Loa Loa (eye worm) transcription factor SMAD2 0.0597 0.1567 0.4508
Loa Loa (eye worm) blistered cuticle protein 3 0.004 0.0075 0.0215
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0005 0.0036
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0048 0.0096 0.0254
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.0101 0.0495
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0163 0.1457
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Loa Loa (eye worm) hypothetical protein 0.0098 0.0228 0.0656
Echinococcus multilocularis chromobox protein 1 0.0068 0.0148 0.0393
Onchocerca volvulus 0.0073 0.0162 0.0783
Brugia malayi hypothetical protein 0.0026 0.0035 0.01
Trypanosoma cruzi hypothetical protein, conserved 0.0253 0.0645 1
Loa Loa (eye worm) intermediate filament protein 0.003 0.0046 0.0133
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0043
Schistosoma mansoni tar DNA-binding protein 0.0124 0.03 0.0801
Echinococcus multilocularis calpain family protein 1, d 0.005 0.01 0.0266
Leishmania major trypanothione reductase 0.0038 0.0067 0.1023
Onchocerca volvulus 0.0023 0.0028 0.0118
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0027
Echinococcus granulosus neuropeptide Y receptor 0.0026 0.0036 0.0093
Echinococcus multilocularis transcription factor btf3 0.0039 0.007 0.0184
Trypanosoma cruzi importin beta-1 subunit, putative 0.005 0.0101 0.1548
Schistosoma mansoni tar DNA-binding protein 0.0124 0.03 0.0801
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Schistosoma mansoni hypothetical protein 0.0026 0.0036 0.0093
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0027 0.0038 0.0333
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0056 0.016
Brugia malayi Pre-SET motif family protein 0.0098 0.0228 0.0656
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0036 0.0093
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0009 0.0021
Onchocerca volvulus 0.0052 0.0107 0.051
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0043 0.0123
Onchocerca volvulus 0.0766 0.2019 1
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0067 0.1031
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0015 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0014
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0038 0.011
Schistosoma mansoni amine GPCR 0.0026 0.0036 0.0093
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0093 0.0215 0.0573
Schistosoma mansoni ran 0.0022 0.0025 0.0062
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Brugia malayi MH2 domain containing protein 0.0041 0.0076 0.0217
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0043 0.0644
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0027 0.0038 0.0333
Brugia malayi ecdysteroid receptor 0.0048 0.0096 0.0276
Echinococcus granulosus nuclear receptor nhr 48 0.0023 0.0028 0.0071
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.0803 0.2309
Brugia malayi glutathione reductase 0.0038 0.0067 0.0193
Mycobacterium ulcerans putative regulatory protein 0.004 0.0073 0.0646
Onchocerca volvulus 0.0052 0.0107 0.051
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0008 0.0526
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0217 0.0577
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0119 0.0286 0.2566
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0096 0.0276
Echinococcus multilocularis FTZ F1 alpha 0.0048 0.0096 0.0254
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0095 0.0222 0.0222
Schistosoma mansoni calpain-7 (C02 family) 0.003 0.0048 0.0124
Schistosoma mansoni opsin-like receptor 0.0026 0.0036 0.0093
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0023 0.0028 0.0071
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Echinococcus multilocularis pyruvate kinase 0.0026 0.0037 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0068 0.0333
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0147
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0427 0.1111 0.3318
Brugia malayi major facilitator superfamily protein 0.0052 0.0107 0.0306
Loa Loa (eye worm) nuclear receptor NHR-67 0.0023 0.0028 0.0079
Echinococcus multilocularis lamin 0.003 0.0046 0.012
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0015 0.0005 0.0036
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0023 0.0059
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0545 0.2693
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0008 0.0017
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0046 0.0133
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0026 0.0036 0.0103
Loa Loa (eye worm) major facilitator superfamily transporter 0.0052 0.0107 0.0306
Loa Loa (eye worm) neuropeptide F receptor 0.0026 0.0036 0.0103
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0069 0.018
Brugia malayi nuclear receptor NHR-88 0.0023 0.0028 0.0079
Echinococcus multilocularis biogenic amine (5HT) receptor 0.039 0.1011 0.2707
Echinococcus granulosus g protein coupled receptor 0.0026 0.0036 0.0093
Brugia malayi Dopamine receptor 0.0026 0.0036 0.0103
Brugia malayi Dopamine receptor protein 1 0.0026 0.0036 0.0103
Brugia malayi MAP kinase sur-1 0.0057 0.012 0.0344
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0079
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0016 0.0009 0.0111
Onchocerca volvulus 0.0048 0.0096 0.0458
Schistosoma mansoni jun-related protein 0.0075 0.0169 0.0448
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0249 0.0664
Leishmania major basic transcription factor 3a, putative 0.0039 0.007 0.1066
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0014 0.0034
Brugia malayi hypothetical protein 0.0073 0.0162 0.0465
Schistosoma mansoni sugar transporter 0.0052 0.0107 0.0282
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0026 0.0036 0.0093
Loa Loa (eye worm) beta-lactamase 0.0253 0.0645 0.1856
Brugia malayi MH2 domain containing protein 0.0597 0.1567 0.4508
Loa Loa (eye worm) hypothetical protein 0.0048 0.0096 0.0276
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Echinococcus granulosus dna polymerase eta 0.0019 0.0017 0.0043
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0021 0.0023 0.0339
Schistosoma mansoni adenoreceptor 0.0026 0.0036 0.0093
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0048 0.0096 0.0254
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0016 0.0009 0.0111
Schistosoma mansoni hypothetical protein 0.035 0.0905 0.2424
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.012 0.1836
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0023 0.0339
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0096 0.0276
Loa Loa (eye worm) hypothetical protein 0.009 0.0208 0.0599
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0056 0.0257
Onchocerca volvulus 0.0026 0.0036 0.0159
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.014 0.0342 0.5285
Brugia malayi hypothetical protein 0.0052 0.0107 0.0306
Echinococcus granulosus aryl hydrocarbon receptor 0.0014 0.0004 0.0007
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0005 0.0063
Loa Loa (eye worm) hypothetical protein 0.0199 0.0501 0.1441
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.012 0.1836
Leishmania major hypothetical protein, conserved 0.0052 0.0107 0.1635
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.0142 0.0409
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0105 0.0249 0.0664
Loa Loa (eye worm) hypothetical protein 0.003 0.0046 0.0133
Schistosoma mansoni hypothetical protein 0.0016 0.0009 0.0021
Onchocerca volvulus 0.0057 0.0119 0.0573
Schistosoma mansoni DNA polymerase eta 0.0019 0.0017 0.0043
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0052 0.0107 0.0282
Brugia malayi hypothetical protein 0.0023 0.0028 0.0079
Brugia malayi nuclear receptor RXR 0.0026 0.0035 0.01
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0026 0.0036 0.0093
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0165 0.0439
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0015 0.0005 0.0036
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0026
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Echinococcus multilocularis abhydrolase domain containing protein 0.0042 0.0079 0.0207
Brugia malayi hypothetical protein 0.0023 0.0028 0.0079
Leishmania major protein kinase, putative 0.002 0.0019 0.0275
Leishmania major protein kinase, putative 0.0015 0.0008 0.0096
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0004 0.0014
Brugia malayi Melatonin receptor type 1A 0.0026 0.0036 0.0103
Trypanosoma brucei unspecified product 0.0019 0.0017 0.0246
Schistosoma mansoni intermediate filament proteins 0.003 0.0046 0.012
Schistosoma mansoni tar DNA-binding protein 0.0124 0.03 0.0801
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0048 0.0734
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.0028 0.0118
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0046 0.0133
Trypanosoma brucei unspecified product 0.0013 0.0001 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0249 0.1228
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0005 0.0036
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0001 0.001
Onchocerca volvulus 0.0015 0.0005 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Echinococcus granulosus mitogen activated protein kinase 14 0.014 0.0342 0.0912
Brugia malayi Dopamine receptor protein 2 0.0026 0.0036 0.0103
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0253 0.0645 0.1726
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.012 0.0317
Echinococcus multilocularis solute carrier family 22 0.0052 0.0107 0.0282
Echinococcus granulosus chromobox protein 1 0.0068 0.0148 0.0393
Echinococcus multilocularis solute carrier family 22 0.0052 0.0107 0.0282
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0661 0.1738 0.5
Echinococcus granulosus pyruvate kinase 0.0033 0.0056 0.0146
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0008 0.0098
Brugia malayi hypothetical protein 0.018 0.045 0.1293
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0093 0.1418
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0199 0.0501 0.2466
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0015 0.0043
Plasmodium falciparum epoxide hydrolase 1 0.0042 0.0079 0.5909
Schistosoma mansoni sugar transporter 0.0052 0.0107 0.0282
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.0036 0.0093
Leishmania major glucose transporter, lmgt3 0.0052 0.0107 0.1635
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0515 0.2547
Echinococcus multilocularis aryl hydrocarbon receptor 0.0014 0.0004 0.0007
Echinococcus granulosus neuropeptide Y receptor 0.0026 0.0036 0.0093
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0099 0.1518
Brugia malayi Bromodomain containing protein 0.0032 0.0053 0.0153
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0048 0.0096 0.0276
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Plasmodium falciparum thioredoxin reductase 0.0038 0.0067 0.5048
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0026 0.0036 0.0103
Onchocerca volvulus 0.0034 0.0059 0.0271
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0005 0.0005
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0008 0.0098
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0047 0.0092 0.0242
Echinococcus granulosus chromobox protein 1 0.0068 0.0148 0.0393
Trichomonas vaginalis esterase, putative 0.0253 0.0645 0.3191
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0056 0.0845
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0017 0.0143
Onchocerca volvulus Protein ultraspiracle homolog 0.0048 0.0096 0.0458
Brugia malayi isocitrate dehydrogenase 0.0015 0.0008 0.0022
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.028 0.0717 0.1918
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0016 0.0009 0.0111
Schistosoma mansoni neuropeptide F-like receptor 0.0026 0.0036 0.0093
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0017 0.0246
Trypanosoma brucei p-glycoprotein 0.0016 0.0009 0.0111
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0099 0.0881
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.0121 0.058
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0141 0.0405
Onchocerca volvulus 0.0058 0.0121 0.058
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.0121 0.032
Echinococcus granulosus serotonin receptor 0.0026 0.0036 0.0093
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0027 0.0038 0.0038
Leishmania major cytochrome p450-like protein 0.0027 0.0038 0.0574
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0109 0.0258 0.0688
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0023 0.0339
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0161 0.0427
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0048 0.0725
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0253 0.0645 0.1856
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0005 0.001
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0001 0.0001
Trypanosoma brucei glucose transporter, putative 0.0052 0.0107 0.1635
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0027 0.0038 0.0333
Plasmodium falciparum thioredoxin reductase 0.0013 0.0001 0.0047
Onchocerca volvulus 0.0052 0.0107 0.051
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0141 0.0405
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0099 0.0285
Schistosoma mansoni pyruvate kinase 0.0017 0.0012 0.0029
Brugia malayi ecdysone receptor 0.0023 0.0028 0.0079
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0027 0.0038 0.0333
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3435 0.9175 0.9175
Echinococcus multilocularis fmrfamide receptor 0.0026 0.0036 0.0093
Brugia malayi hydrolase, alpha/beta fold family protein 0.0042 0.0079 0.0226
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.012 0.1836
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0008 0.0098
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0096 0.0254
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.012 0.0587
Brugia malayi hypothetical protein 0.004 0.0075 0.0215
Echinococcus granulosus sex peptide receptor 0.0026 0.0036 0.0093
Schistosoma mansoni sugar transporter 0.0052 0.0107 0.0282
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0075 0.0215
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0012 0.0878
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0673 0.177 0.5093
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0099 0.0881
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0026 0.0036 0.0103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0036 0.0093
Loa Loa (eye worm) Smad1 0.0041 0.0076 0.0217
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0027 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0017 0.0049
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0093 0.0215 0.0573
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0008 0.0098
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0249 0.1228
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0196 0.0196
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0023 0.0339
Echinococcus granulosus mitogen activated protein kinase 11 0.014 0.0342 0.0912
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0036 0.0093
Echinococcus granulosus solute carrier family 22 0.0052 0.0107 0.0282
Echinococcus multilocularis mothers against decapentaplegic 2 0.0018 0.0015 0.0037
Echinococcus granulosus 7tm_1 domain containing protein 0.0026 0.0036 0.0093
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0048 0.0096 0.0254
Loa Loa (eye worm) hypothetical protein 0.0253 0.0645 0.1856
Brugia malayi Sugar transporter family protein 0.0052 0.0107 0.0306
Schistosoma mansoni hypothetical protein 0.0027 0.0038 0.0099
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0009 0.0021
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0014 0.0034
Schistosoma mansoni hypothetical protein 0.0014 0.0003 0.0005
Brugia malayi Animal haem peroxidase family protein 0.004 0.0075 0.0215
Onchocerca volvulus Serine\/threonine kinase homolog 0.0105 0.0249 0.1215
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0124 0.03 0.0863
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0323 0.0832 0.4116
Loa Loa (eye worm) MH2 domain-containing protein 0.0041 0.0076 0.0217
Giardia lamblia DINP protein human, muc B family 0.0019 0.0017 0.0191
Echinococcus granulosus neuropeptide receptor A26 0.0581 0.1525 0.4087
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0025 0.0062
Schistosoma mansoni amine GPCR 0.0026 0.0036 0.0093
Schistosoma mansoni hypothetical protein 0.0317 0.0816 0.2186
Echinococcus multilocularis calpain 0.0021 0.0023 0.0059
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0016 0.0009 0.0111
Echinococcus multilocularis pyruvate kinase 0.0033 0.0056 0.0146
Brugia malayi beta-lactamase family protein 0.0253 0.0645 0.1856
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0001 0.0002
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0026 0.0036 0.0159
Loa Loa (eye worm) glutathione reductase 0.0038 0.0067 0.0193
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0249 0.1228
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0056 0.0854
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0141 0.0374
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0008 0.0017
Mycobacterium ulcerans esterase/lipase LipP 0.0253 0.0645 0.5804
Schistosoma mansoni chromobox protein 0.0068 0.0148 0.0393
Mycobacterium leprae putative cytochrome p450 0.0027 0.0038 0.0103
Schistosoma mansoni calpain C (C02 family) 0.0021 0.0023 0.0059
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0039 0.0101
Loa Loa (eye worm) hypothetical protein 0.0144 0.0351 0.1011
Echinococcus granulosus Sugar transporter ERD6 protein 0.0052 0.0107 0.0282
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Echinococcus multilocularis tar DNA binding protein 0.0124 0.03 0.0801
Echinococcus granulosus neuropeptide s receptor 0.0581 0.1525 0.4087
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0005 0.0063
Echinococcus multilocularis GPCR, family 2 0.0317 0.0816 0.2186
Brugia malayi hypoxia-induced factor 1 0.0166 0.0412 0.1186
Onchocerca volvulus 0.0026 0.0036 0.0159
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0005 0.0011
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0066 0.4924
Plasmodium vivax acetyl-CoA synthetase, putative 0.0015 0.0005 0.0072
Echinococcus granulosus hypothetical protein 0.0788 0.2079 0.5571
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0048 0.0096 0.0276
Giardia lamblia PHD finger protein 15 0.0028 0.0043 0.0499
Schistosoma mansoni hypothetical protein 0.0812 0.2144 0.5747
Trypanosoma brucei polo-like protein kinase 0.0105 0.0249 0.3844
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0107 0.0523
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0005 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0027 0.0038 0.0038
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0119 0.0343
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0027 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0039 0.0186
Plasmodium vivax calpain, putative 0.0021 0.0023 0.0349
Echinococcus multilocularis smad 0.0041 0.0076 0.0199
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0026 0.0036 0.0103
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1617 0.4302 0.4302
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0014 0.0034
Brugia malayi nuclear hormone receptor 0.0048 0.0096 0.0276
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Onchocerca volvulus 0.0026 0.0036 0.0159
Trypanosoma brucei glucose transporter, putative 0.0052 0.0107 0.1635
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0099 0.0285
Schistosoma mansoni netrin receptor unc5 0.0016 0.0009 0.0021
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0015 0.0005 0.0005
Chlamydia trachomatis pyruvate kinase 0.0033 0.0056 0.0491
Schistosoma mansoni biogenic amine receptor 0.0026 0.0036 0.0093
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0005 0.0005
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0008 0.0108
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0228 0.0608
Echinococcus multilocularis pyruvate kinase 0.0017 0.0012 0.0029
Echinococcus granulosus ubiquitin specific protease 41 0.0047 0.0092 0.0242
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0071 0.0157 0.0418
Loa Loa (eye worm) hypothetical protein 0.005 0.01 0.0289
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0004 0.0014
Entamoeba histolytica transcription factor BTF3, putative 0.0039 0.007 0.0781
Onchocerca volvulus 0.0026 0.0036 0.0159
Schistosoma mansoni histamine h1 receptor 0.0026 0.0036 0.0093
Onchocerca volvulus 0.003 0.0046 0.021
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0009 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0129
Trichomonas vaginalis penicillin-binding protein, putative 0.0253 0.0645 0.3191
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0056 0.0845
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0027 0.0038 0.0038
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0012 0.0179
Brugia malayi nuclear hormone receptor 0.0023 0.0028 0.0079
Schistosoma mansoni nuclear receptor nhr-48 0.0023 0.0028 0.0071
Echinococcus granulosus histone lysine methyltransferase setb 0.0098 0.0228 0.0608
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0014 0.0004 0.0023
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Brugia malayi major facilitator superfamily protein 0.0052 0.0107 0.0306
Loa Loa (eye worm) hydrolase 0.0042 0.0079 0.0226
Trypanosoma brucei glucose transporter 1E 0.0052 0.0107 0.1635
Leishmania major hypothetical protein, conserved 0.003 0.0048 0.0725
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0008 0.0098
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0121 0.032
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0196 0.0196
Brugia malayi G protein-coupled receptor 0.0026 0.0036 0.0103
Schistosoma mansoni smad1 5 8 and 0.0041 0.0076 0.0199
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0048 0.0096 0.0254
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0017 0.0246
Loa Loa (eye worm) hypothetical protein 0.0058 0.0121 0.0347
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0005 0.0063
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0005 0.0036
Brugia malayi jmjC domain containing protein 0.0038 0.0068 0.0194
Echinococcus multilocularis g protein coupled receptor 0.0026 0.0036 0.0093
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.0174 0.0464
Leishmania major cytochrome p450-like protein 0.0027 0.0038 0.0574
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0068 0.0177
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0023 0.0339
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Echinococcus multilocularis neuropeptide Y receptor 0.0026 0.0036 0.0093
Trichomonas vaginalis myo-inositol transporter, putative 0.0052 0.0107 0.0523
Brugia malayi orphan nuclear receptor NR2E1 0.0023 0.0028 0.0079
Echinococcus multilocularis pyruvate kinase 0.0033 0.0056 0.0146
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0027 0.0038 0.0333
Echinococcus granulosus pyruvate kinase 0.0017 0.0012 0.0029
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0092 0.0449
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0093 0.0454
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.012 0.1836
Schistosoma mansoni hypothetical protein 0.0026 0.0036 0.0093
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0323 0.0832 0.4116
Onchocerca volvulus 0.0052 0.0107 0.051
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0056 0.0156
Onchocerca volvulus 0.0052 0.0107 0.051
Echinococcus granulosus G protein coupled receptor 139 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.0049 0.0097 0.028
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.006 0.006
Schistosoma mansoni amine GPCR 0.0026 0.0036 0.0093
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0014 0.0004 0.0014
Schistosoma mansoni pyruvate kinase 0.0033 0.0056 0.0146
Loa Loa (eye worm) sugar transporter 0.0052 0.0107 0.0306
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0005 0.0015
Schistosoma mansoni kinase 0.0054 0.0111 0.0295
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0099 0.0285
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0059 0.0154
Entamoeba histolytica ATP-binding cassette protein, putative 0.0016 0.0009 0.0038
Echinococcus granulosus fmrfamide receptor 0.0026 0.0036 0.0093
Entamoeba histolytica protein kinase, putative 0.0023 0.0027 0.026
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0023 0.0339
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.028 0.0717 0.1918
Brugia malayi follicle stimulating hormone receptor 0.028 0.0717 0.2063
Toxoplasma gondii ABC1 family protein 0.0253 0.0645 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0141 0.0374
Brugia malayi ABC transporter transmembrane region family protein 0.0016 0.0009 0.0024
Loa Loa (eye worm) calpain 0.0021 0.0023 0.0066
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0009 0.0026
Giardia lamblia Fructose-bisphosphate aldolase 0.0323 0.0832 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0099 0.0285
Echinococcus granulosus neuropeptide receptor 0.0026 0.0036 0.0093
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0047 0.0092 0.0242
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0005 0.0005
Echinococcus granulosus solute carrier family 22 0.0052 0.0107 0.0282
Loa Loa (eye worm) hypothetical protein 0.0638 0.1677 0.4823
Schistosoma mansoni thyroid hormone receptor 0.0048 0.0096 0.0254
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.012 0.0317
Brugia malayi chromobox protein homolog 3 0.0038 0.0068 0.0196
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Echinococcus multilocularis geminin 0.1404 0.3731 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Schistosoma mansoni opsin-like receptor 0.0026 0.0036 0.0093
Onchocerca volvulus Peroxidase homolog 0.004 0.0075 0.0352
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.0008 0.0096
Schistosoma mansoni calpain (C02 family) 0.0021 0.0023 0.0059
Brugia malayi ORL1-like opioid receptor 0.0026 0.0036 0.0103
Schistosoma mansoni hypothetical protein 0.1404 0.3731 1
Trypanosoma cruzi sugar transporter, putative 0.0052 0.0107 0.1635
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0048 0.0096 0.0458
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0028 0.0071
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Trypanosoma brucei THT1 - hexose transporter, putative 0.0052 0.0107 0.1635
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0048 0.0725
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0008 0.0022
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0141 0.2169
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.0028 0.0071
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0015 0.0005 0.0036
Toxoplasma gondii propionate-CoA ligase 0.0015 0.0005 0.0063
Onchocerca volvulus 0.0026 0.0036 0.0159
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0068 0.0148 0.0392
Echinococcus multilocularis calpain 5 0.0021 0.0023 0.0059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Onchocerca volvulus 0.0026 0.0036 0.0159
Echinococcus multilocularis conserved hypothetical protein 0.0762 0.201 0.5385
Schistosoma mansoni transient receptor potential channel 0.0078 0.0174 0.0464
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0048 0.3594
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0005 0.0014
Brugia malayi Latrophilin receptor protein 2 0.0317 0.0816 0.2349
Schistosoma mansoni coup transcription factor 0.0048 0.0096 0.0254
Echinococcus multilocularis orexin receptor type 2 0.0026 0.0036 0.0093
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0052 0.0107 0.0282
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0005 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0323 0.0832 0.4116
Mycobacterium tuberculosis Probable lipase LipE 0.0253 0.0645 0.0645
Plasmodium vivax glutathione reductase, putative 0.0038 0.0067 0.1031
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0026 0.0036 0.0093
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0067 0.0067
Brugia malayi CXXC zinc finger family protein 0.0057 0.0119 0.0343
Echinococcus multilocularis dro:myosuppressin receptor 0.0026 0.0036 0.0093
Brugia malayi Pre-SET motif family protein 0.0673 0.177 0.5093
Schistosoma mansoni hypothetical protein 0.0317 0.0816 0.2186
Brugia malayi beta-NAC-like protein 0.0039 0.007 0.0201
Schistosoma mansoni hypothetical protein 0.0026 0.0036 0.0093
Onchocerca volvulus Bile acid receptor homolog 0.0048 0.0096 0.0458
Brugia malayi nuclear hormone receptor family member odr-7 0.0023 0.0028 0.0079
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0026 0.0036 0.0093
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0025 0.0362
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0056 0.016
Entamoeba histolytica ATP-binding cassette protein, putative 0.0016 0.0009 0.0038
Echinococcus granulosus TGF beta signal transducer SmadC 0.0041 0.0076 0.0199
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0025 0.0281
Echinococcus granulosus tar DNA binding protein 0.0124 0.03 0.0801
Echinococcus multilocularis dnaJ subfamily B 0.0812 0.2144 0.5747
Onchocerca volvulus 0.0023 0.0028 0.0118
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.0096 0.0276
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0015 0.0005 0.0063
Onchocerca volvulus 0.0026 0.0036 0.0159
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0147
Echinococcus multilocularis nuclear receptor co repressor related (ncor) 0.0304 0.0782 0.2094
Schistosoma mansoni neuropeptide receptor 0.0026 0.0036 0.0093
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0005 0.0063
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.012 0.0317
Echinococcus granulosus pyruvate kinase 0.0017 0.0012 0.0029
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0043 0.0111
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0023 0.0339
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0027 0.0038 0.0333
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0026 0.0036 0.0093
Echinococcus multilocularis mitogen activated protein kinase 11 0.014 0.0342 0.0912
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.0008 0.0096
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0047 0.0092 0.1402
Onchocerca volvulus 0.0253 0.0645 0.3181
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0026 0.0036 0.0103
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0099 0.0881
Echinococcus granulosus thyroid hormone receptor alpha 0.0023 0.0028 0.0071
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.0036 0.0093
Schistosoma mansoni sugar transporter 0.0052 0.0107 0.0282
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0048 0.0725
Mycobacterium ulcerans integral membrane transport protein 0.0052 0.0107 0.0949
Leishmania major DNA polymerase eta, putative 0.0019 0.0017 0.0246
Echinococcus granulosus biogenic amine 5HT receptor 0.039 0.1011 0.2707
Echinococcus granulosus smad 0.0041 0.0076 0.0199
Onchocerca volvulus Neuropeptide F receptor homolog 0.0026 0.0036 0.0159
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0023 0.0339
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.016 0.0396 0.1057
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0227 0.0575 0.1538
Echinococcus multilocularis somatostatin receptor 0.0026 0.0036 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0803 0.3971
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.0036 0.0093
Echinococcus multilocularis mothers against decapentaplegic 5 0.0041 0.0076 0.0199
Brugia malayi calpain family protein 1 0.0071 0.0157 0.0452
Entamoeba histolytica multidrug resistance protein, putative 0.0016 0.0009 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0079
Echinococcus granulosus beta LACTamase domain containing family member 0.0253 0.0645 0.1726
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0036 0.0093
Brugia malayi Transient-receptor-potential like protein 0.0044 0.0083 0.0239
Echinococcus multilocularis neuropeptide receptor A26 0.0581 0.1525 0.4087
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0803 0.3971
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0803 0.3971
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0163 0.0433
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0017 0.0043
Loa Loa (eye worm) ICD-1 protein 0.0039 0.007 0.0201
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1002 0.2653 0.7632
Echinococcus granulosus calpain 5 0.0021 0.0023 0.0059
Onchocerca volvulus 0.0052 0.0107 0.051
Leishmania major hypothetical protein, conserved 0.0042 0.0079 0.1199
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Brugia malayi MH1 domain containing protein 0.0041 0.0076 0.0217
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0096 0.0254
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0161 0.0427
Mycobacterium leprae conserved hypothetical protein 0.0253 0.0645 0.1922
Onchocerca volvulus 0.0026 0.0036 0.0159
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0029 0.0283
Onchocerca volvulus 0.0026 0.0036 0.0159
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0048 0.3594
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0005 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0014
Trypanosoma cruzi polo-like protein kinase, putative 0.0105 0.0249 0.3844
Brugia malayi hypothetical protein 0.0026 0.0036 0.0103
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0048 0.0096 0.0276
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0038 0.0574
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0005 0.0011
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0056 0.0056
Echinococcus multilocularis G-protein coupled receptor, putative 0.0026 0.0036 0.0093
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0027 0.0038 0.0333
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0163 0.0163
Echinococcus granulosus biogenic amine 5HT receptor 0.0144 0.0351 0.0939
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0023 0.0028 0.0071
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Brugia malayi CHD4 protein 0.0014 0.0005 0.0014
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0016 0.0009 0.0111
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0515 0.2547
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.2592 0.6946
Plasmodium falciparum pyruvate kinase 0.0033 0.0056 0.418
Schistosoma mansoni growth hormone secretagogue receptor 0.0026 0.0036 0.0093
Brugia malayi nuclear receptor NHR-88 0.0048 0.0096 0.0276
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Schistosoma mansoni cytochrome P450 0.0027 0.0038 0.0099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Echinococcus multilocularis neuropeptide FF receptor 2 0.0026 0.0036 0.0093
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0005 0.0005
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0015 0.0005 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0015
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0017 0.0043
Loa Loa (eye worm) TYRA-2 protein 0.0026 0.0036 0.0103
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0026 0.0036 0.0093
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0038 0.0574
Entamoeba histolytica calpain large subunit domain III containing protein 0.0021 0.0023 0.0216
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0027 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0048 0.0096 0.0276
Giardia lamblia MRP-like ABC transporter 0.0016 0.0009 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0014
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0017 0.0049
Trypanosoma brucei glucose transporter, putative 0.0052 0.0107 0.1635
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0803 0.3971
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0005 0.0005
Onchocerca volvulus Putative transporter 0.0052 0.0107 0.051
Echinococcus granulosus dro:myosuppressin receptor 0.0026 0.0036 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.007 0.0341
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.012 0.1836
Echinococcus granulosus TRP transient receptor potential channel 0.0044 0.0083 0.022
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0105 0.0249 0.3844
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0048 0.0096 0.0276
Onchocerca volvulus 0.0026 0.0036 0.0159
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.0121 0.032
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0056 0.0257
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.012 0.0587
Onchocerca volvulus 0.004 0.0075 0.0352
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0147
Entamoeba histolytica hypothetical protein 0.0072 0.0161 0.1878
Trypanosoma brucei kinesin, putative 0.0021 0.0023 0.0339
Echinococcus granulosus transcription factor btf3 0.0039 0.007 0.0184
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0005 0.0063
Mycobacterium tuberculosis Probable esterase LipL 0.0253 0.0645 0.0645
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0323 0.0832 1
Brugia malayi Serotonin receptor 0.0026 0.0036 0.0103
Plasmodium falciparum glutathione reductase 0.0038 0.0067 0.5048
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0016 0.0009 0.0111
Echinococcus multilocularis pyruvate kinase 0.0017 0.0012 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0323 0.0832 0.4116
Echinococcus multilocularis Ankyrin 0.0016 0.0009 0.0022
Brugia malayi hypothetical protein 0.017 0.0422 0.1212
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0107 0.0523
Giardia lamblia Multidrug resistance-associated protein 1 0.0016 0.0009 0.0086
Loa Loa (eye worm) hypothetical protein 0.0026 0.0035 0.01
Leishmania major pyruvate kinase 0.0033 0.0056 0.0845
Brugia malayi G-protein coupled receptor 0.0026 0.0036 0.0103
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0052 0.0107 0.0282
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0253 0.0645 0.5804
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0015 0.0068
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0228 0.0608
Giardia lamblia Kinase, PLK 0.0105 0.0249 0.298
Onchocerca volvulus 0.0015 0.0005 0.0008
Brugia malayi MH1 domain containing protein 0.0041 0.0076 0.0217
Loa Loa (eye worm) hypothetical protein 0.0253 0.0645 0.1856
Mycobacterium tuberculosis Probable oxidoreductase 0.0095 0.0222 0.0222
Schistosoma mansoni Smad4 0.0018 0.0015 0.0037
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.012 0.1836
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0026 0.0036 0.0093
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0047 0.0092 0.0242
Loa Loa (eye worm) hypothetical protein 0.0026 0.0035 0.01
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.0515 0.2536
Chlamydia trachomatis recombinase RecA 0.0119 0.0286 0.2566
Onchocerca volvulus 0.0052 0.0107 0.051
Chlamydia trachomatis replicative DNA helicase 0.0427 0.1111 1
Trichomonas vaginalis D-aminoacylase, putative 0.0253 0.0645 0.3191
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Loa Loa (eye worm) hypothetical protein 0.0037 0.0066 0.0188
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0023 0.0028 0.0071
Echinococcus multilocularis neuropeptides capa receptor 0.0026 0.0036 0.0093
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0023 0.0028 0.0071
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0005 0.0063
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0056 0.0845
Mycobacterium ulcerans lipase LipD 0.0253 0.0645 0.5804
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0038 0.0574
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0147
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0148 0.0728
Echinococcus granulosus nuclear receptor co repressor related ncor 0.0304 0.0782 0.2094
Echinococcus multilocularis neuropeptide s receptor 0.0581 0.1525 0.4087
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0093 0.0454
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0048 0.0096 0.0254
Schistosoma mansoni neuropeptide F-like receptor 0.0026 0.0036 0.0093
Schistosoma mansoni transcription factor btf3 0.0039 0.007 0.0184
Trypanosoma cruzi hexose transporter, putative 0.0052 0.0107 0.1635
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0026 0.0036 0.0093
Mycobacterium ulcerans hypothetical protein 0.0049 0.0099 0.0881
Entamoeba histolytica hypothetical protein 0.0072 0.0161 0.1878
Brugia malayi G-protein coupled receptor 0.0026 0.0036 0.0103
Trypanosoma brucei hypothetical protein, conserved 0.0253 0.0645 1
Schistosoma mansoni nuclear receptor 0.0023 0.0028 0.0071
Echinococcus granulosus Ankyrin 0.0016 0.0009 0.0022
Trypanosoma brucei glucose transporter, putative 0.0052 0.0107 0.1635
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.028 0.0717 0.1918
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0044 0.0083 0.022
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0068 0.0148 0.0392
Entamoeba histolytica serine/threonine protein kinase, putative 0.0105 0.0249 0.2946
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0249 0.1228
Loa Loa (eye worm) RNA binding protein 0.0124 0.03 0.0863
Echinococcus multilocularis allatostatin A receptor 0.0026 0.0036 0.0093
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0027 0.0038 0.0333
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0005 0.0036
Brugia malayi acetyltransferase, GNAT family protein 0.016 0.0396 0.1138
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0141 0.0374
Onchocerca volvulus Peroxidase homolog 0.004 0.0075 0.0352
Schistosoma mansoni glucose transport protein 0.0052 0.0107 0.0282
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0027 0.0038 0.0333
Schistosoma mansoni hypothetical protein 0.0317 0.0816 0.2186
Mycobacterium tuberculosis Probable hydrolase 0.0253 0.0645 0.0645
Plasmodium vivax sugar transporter, putative 0.0052 0.0107 0.1643
Brugia malayi Protein kinase domain containing protein 0.0017 0.0013 0.0036
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0015 0.0068
Brugia malayi putative neuropeptide receptor 0.0026 0.0036 0.0103
Brugia malayi serine/threonine-protein kinase plk-2 0.0105 0.0249 0.0716
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.006 0.006
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0026 0.0035 0.009
Plasmodium vivax hexose transporter 0.0052 0.0107 0.1643
Echinococcus granulosus abhydrolase domain containing protein 0.0042 0.0079 0.0207
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0012 0.0055
Onchocerca volvulus 0.0052 0.0107 0.051
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0009 0.0026
Onchocerca volvulus 0.0026 0.0036 0.0159
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Loa Loa (eye worm) hypothetical protein 0.0037 0.0066 0.0188
Echinococcus granulosus mothers against decapentaplegic 2 0.0018 0.0015 0.0037
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0158 0.0389 0.0389
Schistosoma mansoni cpg binding protein 0.006 0.0128 0.034
Echinococcus multilocularis multidrug resistance associated protein 1 0.0016 0.0009 0.0019
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Brugia malayi Major Facilitator Superfamily protein 0.0052 0.0107 0.0306
Plasmodium falciparum basic transcription factor 3b, putative 0.0039 0.007 0.5259
Echinococcus granulosus death domain containing protein 0.0016 0.0009 0.0021
Schistosoma mansoni RAR-like nuclear receptor 0.0048 0.0096 0.0254
Loa Loa (eye worm) hypothetical protein 0.0071 0.0157 0.0452
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0079
Loa Loa (eye worm) melatonin receptor type 1A 0.0026 0.0036 0.0103
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0005 0.0009
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0043 0.0653
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0008 0.0098
Plasmodium falciparum phd finger protein, putative 0.0028 0.0043 0.3197
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0023 0.0028 0.0079
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0015 0.0005 0.0063
Echinococcus granulosus calpain 0.0021 0.0023 0.0059
Echinococcus multilocularis g protein coupled receptor 0.0026 0.0036 0.0093
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0027 0.0038 0.0333
Schistosoma mansoni neuropeptide receptor 0.0026 0.0036 0.0093
Echinococcus granulosus calpain A 0.0021 0.0023 0.0059
Trypanosoma brucei protein kinase, putative 0.0057 0.012 0.1836
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Giardia lamblia Sugar-proton symporter 0.0052 0.0107 0.1267
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.03 0.0802
Trypanosoma cruzi hexose transporter, putative 0.0052 0.0107 0.1635
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0158 0.0389 0.1155
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.028 0.0717 0.1918
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0016 0.0009 0.0111
Brugia malayi Peroxidasin 0.004 0.0075 0.0215
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0048 0.0096 0.0254
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0008 0.0022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0099 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0039 0.0186
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0079
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0015 0.0005 0.0005
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0076 0.0371
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0068 0.0178
Onchocerca volvulus 0.0109 0.0258 0.126
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Loa Loa (eye worm) calpain family protein 1 0.0071 0.0157 0.0452
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0027 0.0038 0.0038
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.0008 0.0096
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1309 0.3476 1
Onchocerca volvulus 0.003 0.0046 0.021
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0027 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0079
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Schistosoma mansoni hypothetical protein 0.0075 0.0169 0.0448
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0026 0.0036 0.0103
Echinococcus multilocularis transfer RNA-Lys 0.004 0.0073 0.0192
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0026 0.0036 0.0093
Schistosoma mansoni myosin xvIII 0.0026 0.0036 0.0093
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0027 0.0038 0.0574
Echinococcus granulosus solute carrier family 22 0.0052 0.0107 0.0282
Mycobacterium ulcerans sugar transporter 0.0052 0.0107 0.0949
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0082
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0323 0.0832 0.4116
Trypanosoma brucei transcription factor BTF3, putative 0.0039 0.007 0.1066
Loa Loa (eye worm) hypothetical protein 0.018 0.045 0.1293
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0048 0.0096 0.0254
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0008 0.0098
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0005 0.0005
Brugia malayi putative neuropeptide receptor NPR1 0.0026 0.0036 0.0103
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0253 0.0645 0.0645
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0052 0.0107 0.0282
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0163 0.0433
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0075 0.0215
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0005 0.0015
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.014 0.0342 0.5285
Schistosoma mansoni amine GPCR 0.0346 0.0894 0.2393
Loa Loa (eye worm) nuclear factor I 0.0022 0.0027 0.0077
Echinococcus granulosus Smad4 0.0041 0.0076 0.0199
Schistosoma mansoni importin beta-1 0.0062 0.0132 0.0351
Schistosoma mansoni opsin-like receptor 0.0026 0.0036 0.0093
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0056 0.0271
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0099 0.0099
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0096 0.0254
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0005 0.0009
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.007 0.1066
Brugia malayi Cytochrome P450 family protein 0.0027 0.0038 0.011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0323 0.0832 0.4116
Brugia malayi small heat shock protein 0.0638 0.1677 0.4823
Schistosoma mansoni tar DNA-binding protein 0.0124 0.03 0.0801
Schistosoma mansoni hypothetical protein 0.1404 0.3731 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0036 0.0093
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0027 0.0038 0.0333
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0163 0.0433
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0017 0.0017
Echinococcus multilocularis transient receptor potential ion channel A 0.0113 0.027 0.0721
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0427 0.1111 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0196 0.0196
Onchocerca volvulus 0.0023 0.0028 0.0121
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.012 0.0317
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.0101 0.0495
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0041 0.0076 0.0199
Entamoeba histolytica hypothetical protein 0.0072 0.0161 0.1878
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.0142 0.0378
Schistosoma mansoni transient receptor potential channel 0.0117 0.0281 0.0749
Echinococcus granulosus somatostatin receptor 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Toxoplasma gondii sugar transporter ST2 0.0052 0.0107 0.1635
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0079
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0008 0.0008
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Loa Loa (eye worm) hypothetical protein 0.003 0.0048 0.0138
Echinococcus multilocularis synaptic vesicle 2 protein 0.0053 0.0107 0.0284
Toxoplasma gondii sugar transporter ST3 0.0052 0.0107 0.1635
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.012 0.0317
Brugia malayi Animal haem peroxidase family protein 0.004 0.0075 0.0215
Toxoplasma gondii transporter, major facilitator family protein 0.0052 0.0107 0.1635
Schistosoma mansoni neuropeptide receptor 0.0026 0.0036 0.0093
Brugia malayi conserved hypotetical protein 0.0023 0.0028 0.0079
Brugia malayi hypothetical protein 0.0026 0.0036 0.0103
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0038 0.011
Brugia malayi AKH receptor 0.0026 0.0036 0.0103
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0121 0.032
Toxoplasma gondii sugar transporter ST1 0.0052 0.0107 0.1635
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0108 0.0528
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0005 0.0015
Brugia malayi Calcitonin receptor-like protein seb-1 0.1002 0.2653 0.7632
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0323 0.0832 0.4116
Trichomonas vaginalis ran, putative 0.0022 0.0025 0.0117
Entamoeba histolytica hypothetical protein 0.005 0.0101 0.1157
Echinococcus multilocularis ubiquitin specific protease 41 0.0047 0.0092 0.0242
Echinococcus multilocularis mothers against decapentaplegic 6 0.0018 0.0015 0.0037
Entamoeba histolytica Ran family GTPase 0.0022 0.0025 0.0233
Brugia malayi hypothetical protein 0.0026 0.0036 0.0103
Echinococcus granulosus g protein coupled receptor 0.0026 0.0036 0.0093
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0017 0.0143
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0515 0.2547
Onchocerca volvulus 0.0049 0.0099 0.0472
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0005 0.0009
Echinococcus multilocularis musashi 0.003 0.0046 0.012
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.0036 0.0093
Schistosoma mansoni calpain-7 (C02 family) 0.003 0.0048 0.0124
Echinococcus granulosus cpg binding protein 0.006 0.0128 0.034
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0015 0.0005 0.0005
Echinococcus multilocularis transient receptor potential gamma protein 0.0117 0.0281 0.0749
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.0142 0.0378
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Echinococcus granulosus lamin 0.003 0.0046 0.012
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0052 0.0107 0.0282
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0026 0.0036 0.0093
Echinococcus multilocularis calpain 7 (C02 family) 0.0021 0.0023 0.0059
Loa Loa (eye worm) nuclear hormone receptor 0.0023 0.0028 0.0079
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0023 0.0339
Brugia malayi nuclear receptor NHR-67 0.0023 0.0028 0.0079
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0025 0.0362
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0068 0.0333
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0026 0.0036 0.0093
Echinococcus granulosus Solute carrier family 22 5 0.1143 0.3032 0.8126
Onchocerca volvulus 0.0052 0.0107 0.051
Loa Loa (eye worm) hypothetical protein 0.0066 0.0142 0.0409
Onchocerca volvulus 0.004 0.0075 0.0352
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0147
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0005 0.0015
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.0142 0.0378
Entamoeba histolytica ATP-binding cassette protein, putative 0.0016 0.0009 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0515 0.2547
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0082 0.6183
Loa Loa (eye worm) cytochrome P450 family protein 0.015 0.0369 0.1062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0049
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.0121 0.032
Loa Loa (eye worm) G-protein coupled receptor 0.0026 0.0036 0.0103
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0096 0.0276
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0023 0.0339
Echinococcus granulosus dna polymerase kappa 0.0019 0.0017 0.0043
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Entamoeba histolytica hypothetical protein 0.0039 0.007 0.0781
Echinococcus multilocularis beta LACTamase domain containing family member 0.0253 0.0645 0.1726
Brugia malayi Major Facilitator Superfamily protein 0.0052 0.0107 0.0306
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0048 0.0096 0.0254
Onchocerca volvulus 0.0026 0.0036 0.0159
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Onchocerca volvulus Alhambra homolog 0.0028 0.0043 0.0193
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0056 0.0845
Trypanosoma cruzi glucose transporter, putative 0.0052 0.0107 0.1635
Brugia malayi MH1 domain containing protein 0.0022 0.0027 0.0077
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0323 0.0832 0.4116
Trypanosoma cruzi hexose transporter, putative 0.0052 0.0107 0.1635
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0023 0.0339
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0001 0.0001
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0018 0.0015 0.0056
Mycobacterium ulcerans hypothetical protein 0.0253 0.0645 0.5804
Brugia malayi hypothetical protein 0.0026 0.0036 0.0103
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0249 0.1228
Plasmodium vivax basic transcription factor 3b, putative 0.0039 0.007 0.1074
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0048 0.0096 0.0254
Onchocerca volvulus 0.0015 0.0005 0.0008
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0026 0.0036 0.0093
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0041 0.0076 0.0199
Loa Loa (eye worm) hypothetical protein 0.0685 0.1803 0.5187
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0098 0.0228 0.3521
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0005 0.0005
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0076 0.0371
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0052 0.0107 0.0282
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0515 0.2547
Echinococcus multilocularis thyroid hormone receptor alpha 0.0048 0.0096 0.0254
Echinococcus granulosus lamin dm0 0.003 0.0046 0.012
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0017 0.0043
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0027 0.0038 0.0333
Echinococcus granulosus multidrug resistance associated protein 7 0.0016 0.0009 0.0019
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0005 0.0063
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Onchocerca volvulus 0.0253 0.0645 0.3181
Leishmania major glucose transporter, lmgt1 0.0052 0.0107 0.1635
Onchocerca volvulus 0.004 0.0075 0.0352
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0099 0.0881
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0026 0.0036 0.0093
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0056 0.016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0147
Echinococcus granulosus pyruvate kinase 0.0033 0.0056 0.0146
Leishmania major GTP-binding protein, putative 0.0022 0.0025 0.0362
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0141 0.1641
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0317 0.0816 0.2349
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0043 0.0111
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.012 0.1836
Onchocerca volvulus 0.003 0.0046 0.021
Echinococcus multilocularis neuropeptide receptor 0.0026 0.0036 0.0093
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0001 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0096 0.0276
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0246
Brugia malayi hypothetical protein 0.0052 0.0107 0.0306
Brugia malayi tailless protein 0.0023 0.0028 0.0079
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0056 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0107 0.0523
Onchocerca volvulus Netrin receptor homolog 0.0016 0.0009 0.0025
Mycobacterium tuberculosis Conserved protein 0.0253 0.0645 0.0645
Schistosoma mansoni hypothetical protein 0.0072 0.0161 0.0427
Treponema pallidum fructose-bisphosphate aldolase 0.0323 0.0832 0.7486
Brugia malayi Animal haem peroxidase family protein 0.004 0.0075 0.0215
Echinococcus granulosus jun protein 0.0093 0.0215 0.0573
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.0004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0105 0.0249 0.0716
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0023
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0025 0.0071
Brugia malayi Major Facilitator Superfamily protein 0.0052 0.0107 0.0306
Brugia malayi calpain family protein 1 0.0071 0.0157 0.0452
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.0121 0.032
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0075 0.0167 0.0444
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0803 0.3971
Brugia malayi PHD-finger family protein 0.0028 0.0043 0.0123
Echinococcus granulosus jumonji domain containing protein 0.004 0.0073 0.0191
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0036 0.0093
Plasmodium vivax hypothetical protein, conserved 0.0253 0.0645 1
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0027 0.0038 0.0038
Echinococcus granulosus transient receptor potential ion channel A 0.0113 0.027 0.0721
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0025 0.0362
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0052 0.0107 0.0949
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0253 0.0645 0.0645
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0317 0.0816 0.2186
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0624 0.1639 0.4392
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0005 0.0021
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0026 0.0036 0.0093
Trichomonas vaginalis penicillin-binding protein, putative 0.0253 0.0645 0.3191
Schistosoma mansoni smad 0.0041 0.0076 0.0199
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0052 0.0107 0.0282
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0027 0.0038 0.0038
Brugia malayi nuclear receptor RXR 0.0023 0.0028 0.0079
Echinococcus multilocularis mitogen activated protein kinase 11 0.014 0.0342 0.0912
Loa Loa (eye worm) hypothetical protein 0.0071 0.0157 0.0452
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0249 0.1228
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0052 0.0107 0.8041
Brugia malayi MH2 domain containing protein 0.0041 0.0076 0.0217
Schistosoma mansoni glucose transport protein 0.0052 0.0107 0.0282
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0004 0.0014
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0005 0.0036
Onchocerca volvulus 0.0052 0.0107 0.051
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0014 0.0034
Plasmodium falciparum hexose transporter 0.0052 0.0107 0.8041
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0026 0.0036 0.0093
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0095 0.0222 0.0653
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Loa Loa (eye worm) hypothetical protein 0.0026 0.0035 0.01
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0013 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.007 0.0341
Loa Loa (eye worm) hypothetical protein 0.003 0.0046 0.0133
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0096 0.0254
Plasmodium vivax importin-beta 2, putative 0.0062 0.0132 0.2043
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0048 0.0137
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.0008 0.0096
Brugia malayi intermediate filament protein 0.003 0.0046 0.0133
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0004 0.0014
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.0147
Echinococcus multilocularis G protein coupled receptor 139 0.0026 0.0036 0.0093
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0067 0.1023
Onchocerca volvulus Peroxidasin homolog 0.004 0.0075 0.0352
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0163 0.0433
Onchocerca volvulus 0.0052 0.0107 0.051
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.001
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0005 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0005 0.0015
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0023 0.0339
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0036 0.0093
Brugia malayi photoreceptor-specific nuclear receptor 0.0048 0.0096 0.0276
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0023 0.0339
Schistosoma mansoni single-minded 0.0054 0.011 0.0293
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0068 0.0148 0.2274
Trypanosoma cruzi kinesin, putative 0.0021 0.0023 0.0339
Onchocerca volvulus 0.0026 0.0036 0.0159
Brugia malayi bZIP transcription factor family protein 0.0093 0.0215 0.0618
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0148 0.0426
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0158 0.0389 0.3496
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0015 0.0005 0.0354
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.0306
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0038 0.011
Echinococcus granulosus synaptic vesicle 2 protein 0.0053 0.0107 0.0284
Echinococcus multilocularis ecdysone induced protein 78C 0.0048 0.0096 0.0254
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0075 0.0167 0.0444
Trichomonas vaginalis sugar transporter, putative 0.0052 0.0107 0.0523
Loa Loa (eye worm) hypothetical protein 0.017 0.0422 0.1212
Onchocerca volvulus 0.0052 0.0107 0.051
Toxoplasma gondii cytochrome p450 superfamily protein 0.0027 0.0038 0.0574
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0103
Schistosoma mansoni hypothetical protein 0.0661 0.1738 0.4656
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0036 0.0093
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0026 0.0036 0.0093
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0209
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0025 0.0371
Loa Loa (eye worm) follicle stimulating hormone receptor 0.028 0.0717 0.2063
Echinococcus multilocularis mitogen activated protein kinase 14 0.014 0.0342 0.0912
Loa Loa (eye worm) hypothetical protein 0.0053 0.0107 0.0308
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0215
Brugia malayi Steroid receptor seven-up type 2 0.0048 0.0096 0.0276
Loa Loa (eye worm) steroid hormone receptor 0.0048 0.0096 0.0276
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0027 0.0038 0.0574
Onchocerca volvulus 0.0026 0.0036 0.0159
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.012 0.0587
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0108 0.0528
Loa Loa (eye worm) hypothetical protein 0.0049 0.0099 0.0285
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0016 0.0009 0.0111
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0026 0.0036 0.0093
Trypanosoma cruzi DNA repair protein, putative 0.0037 0.0065 0.0986
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0009 0.0021
Giardia lamblia Multidrug resistance-associated protein 1 0.0016 0.0008 0.0082
Brugia malayi Serotonin receptor 0.0026 0.0036 0.0103
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0026 0.0036 0.0093
Brugia malayi Animal haem peroxidase family protein 0.004 0.0075 0.0215
Onchocerca volvulus 0.004 0.0073 0.0343
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0099 0.0881
Schistosoma mansoni thyroid hormone receptor 0.0048 0.0096 0.0254
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0023 0.0339
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0092 0.0449
Entamoeba histolytica hypothetical protein 0.0072 0.0161 0.1878

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 3.6964 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 50.1187 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) = 70.7946 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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