Detailed information for compound 311642

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 583.677 | Formula: C33H37N5O5
  • H donors: 4 H acceptors: 5 LogP: 4.61 Rotable bonds: 18
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C[C@H](NC(=O)C(Cc1c[nH]cn1)NC(=O)C(Cc1cccc2c1cccc2)NC(=O)OCc1ccccc1)CC(C)C
  • InChi: 1S/C33H37N5O5/c1-22(2)15-27(19-39)36-31(40)30(17-26-18-34-21-35-26)37-32(41)29(38-33(42)43-20-23-9-4-3-5-10-23)16-25-13-8-12-24-11-6-7-14-28(24)25/h3-14,18-19,21-22,27,29-30H,15-17,20H2,1-2H3,(H,34,35)(H,36,40)(H,37,41)(H,38,42)/t27-,29?,30?/m0/s1
  • InChiKey: ZUEGHEHOPXDNRU-MQPDAGPXSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0059 0.0051 0.0011
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0064 0.0108 0.0069
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0061 0.0067 0.0034
Onchocerca volvulus 0.0062 0.0079 0.0065
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.0247 0.027
Loa Loa (eye worm) TK/ROR protein kinase 0.009 0.0389 0.0423
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0105 0.0542 0.136
Echinococcus multilocularis neural cadherin 0.0071 0.0177 0.0168
Loa Loa (eye worm) hypothetical protein 0.0131 0.0822 0.0893
Plasmodium falciparum calcium-dependent protein kinase 3 0.0098 0.0473 0.0611
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0228 0.1879 0.2245
Echinococcus granulosus serine threonine protein kinase nrc 0.0152 0.1052 0.1017
Echinococcus multilocularis tyrosine protein kinase Fgr 0.022 0.1784 0.2128
Loa Loa (eye worm) hypothetical protein 0.0107 0.0569 0.0618
Brugia malayi Tyrosine-protein kinase abl-1 0.0135 0.087 0.0945
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0125 0.0762 0.1029
Echinococcus multilocularis tyrosine protein kinase Src64B 0.022 0.1784 0.2128
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0574 0.0735
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0092 0.0406 0.0448
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0125 0.0762 0.0881
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0079 0.0271 0.0295
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0064 0.0108 0.0124
Schistosoma mansoni netrin receptor unc5 0.0075 0.0228 0.0244
Echinococcus multilocularis c4b binding protein beta chain 0.0131 0.0822 0.0956
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.009 0.0389 0.0427
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0079 0.0271 0.0284
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.011 0.0599 0.0716
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.061 0.2243
Brugia malayi Protein kinase domain containing protein 0.0194 0.151 0.164
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Plasmodium falciparum glycogen synthase kinase 3 0.0125 0.0762 0.1029
Echinococcus granulosus metabotropic glutamate receptor 5 0.0793 0.797 0.7963
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0081 0.0288 0.032
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Echinococcus granulosus serine:threonine kinase SAD 1 0.0087 0.0354 0.0316
Trypanosoma cruzi casein kinase, putative 0.0106 0.0554 0.0705
Echinococcus granulosus tyrosine protein kinase Blk 0.0183 0.1387 0.1354
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0112 0.0621 0.0709
Echinococcus multilocularis netrin receptor unc 5 0.0075 0.0228 0.023
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.021 0.1685 0.183
Trichomonas vaginalis AGC family protein kinase 0.0141 0.0936 0.3548
Giardia lamblia Kinase, CMGC SRPK 0.0081 0.0288 0.0848
Echinococcus granulosus translocator protein 0.0282 0.2457 0.2428
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0098 0.0474 0.1234
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Schistosoma mansoni growth factor receptor-bound protein 0.0091 0.0394 0.0473
Schistosoma mansoni hypothetical protein 0.0071 0.0177 0.0174
Trypanosoma cruzi rac serine-threonine kinase, putative 0.016 0.1145 0.1562
Entamoeba histolytica protein kinase, putative 0.0282 0.2454 0.7245
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0242 0.203 0.8181
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.153 0.2036
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0194 0.151 0.164
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0448 0.4253 0.5141
Echinococcus granulosus tyrosine protein kinase otk 0.0092 0.0406 0.0369
Echinococcus granulosus delta-like protein 1 0.0071 0.0177 0.0138
Echinococcus multilocularis N chimaerin 0.0092 0.0412 0.0454
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0132 0.0839 0.1141
Brugia malayi Furin-like cysteine rich region family protein 0.059 0.5779 0.6276
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0081 0.0288 0.0344
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0084 0.0319 0.0281
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0092 0.0412 0.0497
Onchocerca volvulus 0.0071 0.0177 0.0339
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0098 0.0473 0.0513
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0081 0.0288 0.0313
Entamoeba histolytica protein kinase domain containing protein 0.0097 0.0465 0.1207
Schistosoma mansoni tyrosine kinase 0.0107 0.0564 0.0707
Echinococcus granulosus serine:threonine protein kinase 0.0111 0.061 0.0574
Onchocerca volvulus 0.0314 0.2802 0.7678
Echinococcus multilocularis cyclin 0.0202 0.1596 0.1899
Entamoeba histolytica protein kinase, putative 0.0072 0.0186 0.0361
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0621 0.2284
Echinococcus granulosus dual specificity 0.0135 0.0869 0.0833
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.1169 0.154
Echinococcus granulosus dual specificity protein kinase clk2 0.0149 0.1021 0.0986
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0061 0.0067 0.0073
Trichomonas vaginalis AGC family protein kinase 0.0163 0.1169 0.4483
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.2232 0.8741
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0149 0.1021 0.1383
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0125 0.0762 0.1007
Loa Loa (eye worm) hypothetical protein 0.0111 0.061 0.0663
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0084 0.0319 0.0341
Schistosoma mansoni titin 0.0092 0.0406 0.049
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0224 0.1836 0.1994
Brugia malayi hypothetical protein 0.0215 0.1733 0.1882
Leishmania major protein kinase A catalytic subunit 0.011 0.0599 0.0771
Echinococcus granulosus roundabout 2 0.0279 0.2428 0.2399
Schistosoma mansoni laminin gamma-3 chain 0.0071 0.0177 0.0174
Loa Loa (eye worm) AGC/NDR protein kinase 0.0163 0.1169 0.127
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Brugia malayi MAP kinase sur-1 0.0082 0.0295 0.032
Entamoeba histolytica hypothetical protein 0.0366 0.3361 1
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0098 0.0473 0.0532
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.011 0.0599 0.0683
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0098 0.0473 0.0611
Loa Loa (eye worm) AGC/PKG protein kinase 0.0131 0.0823 0.0894
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0215 0.1733 0.1701
Onchocerca volvulus 0.0131 0.0822 0.2144
Brugia malayi Protein kinase domain containing protein 0.021 0.1679 0.1823
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0107 0.0569 0.0647
Schistosoma mansoni glutamate synthase 0.0064 0.0108 0.0079
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0062 0.0083 0.009
Brugia malayi Temporarily assigned gene name protein 59 0.0124 0.0754 0.0818
Schistosoma mansoni tyrosine kinase 0.0357 0.3265 0.4424
Entamoeba histolytica serine/threonine protein kinase, putative 0.0261 0.2232 0.6573
Schistosoma mansoni protein kinase 0.0419 0.3932 0.5341
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0159 0.1129 0.133
Loa Loa (eye worm) glutathione reductase 0.07 0.6964 0.7562
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0261 0.2232 0.2202
Schistosoma mansoni tyrosine kinase 0.0304 0.2691 0.3634
Brugia malayi Protein kinase domain containing protein 0.0539 0.523 0.5679
Echinococcus granulosus protein kinase shaggy 0.0125 0.0762 0.0725
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0061 0.0067 0.0034
Loa Loa (eye worm) hypothetical protein 0.0231 0.1904 0.2068
Loa Loa (eye worm) hypothetical protein 0.0086 0.0341 0.037
Loa Loa (eye worm) hypothetical protein 0.0138 0.0905 0.0983
Loa Loa (eye worm) hypothetical protein 0.0793 0.797 0.8656
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0135 0.0869 0.0943
Trypanosoma brucei cdc2-related kinase 3 0.0115 0.0659 0.0804
Echinococcus multilocularis neuroglian 0.0107 0.0569 0.0647
Brugia malayi phosphoinositide-dependent protein kinase I 0.0079 0.0271 0.0295
Entamoeba histolytica protein kinase domain containing protein 0.0119 0.0695 0.1905
Brugia malayi Receptor family ligand binding region containing protein 0.0165 0.1195 0.1298
Echinococcus granulosus neurogenic locus notch protein 0.0071 0.0177 0.0138
Onchocerca volvulus 0.0071 0.0177 0.0339
Schistosoma mansoni tyrosine kinase 0.0251 0.2128 0.2859
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0119 0.0695 0.091
Schistosoma mansoni tyrosine kinase 0.0076 0.0236 0.0256
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0064 0.0108 0.0231
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0079 0.0264 0.0309
Echinococcus granulosus mitogen activated protein kinase 3 0.0082 0.0295 0.0257
Giardia lamblia Kinase, CK1 Casein kinase 0.0106 0.0554 0.2098
Brugia malayi Protein kinase domain 0.0084 0.0319 0.0346
Loa Loa (eye worm) hypothetical protein 0.0061 0.0067 0.0073
Echinococcus granulosus casein kinase I alpha 0.0106 0.0554 0.0517
Echinococcus granulosus insulin receptor 0.0433 0.409 0.4067
Echinococcus granulosus tyrosine protein kinase Fyn 0.022 0.1784 0.1751
Brugia malayi SH2 domain containing protein 0.0098 0.0474 0.0515
Giardia lamblia Kinase, STE STE20 0.0084 0.0319 0.099
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0061 0.0073 0.0089
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0119 0.0695 0.0755
Entamoeba histolytica protein kinase, putative 0.0163 0.1169 0.3346
Brugia malayi EGF-like domain containing protein 0.0071 0.0177 0.0192
Plasmodium falciparum serine/threonine protein kinase 0.0081 0.0288 0.0344
Echinococcus multilocularis casein kinase ii subunit alpha 0.0097 0.0465 0.052
Loa Loa (eye worm) CAMK protein kinase 0.0092 0.0409 0.0444
Brugia malayi ephrin receptor 1 precursor 0.0075 0.0224 0.0243
Brugia malayi Immunoglobulin I-set domain containing protein 0.0187 0.1436 0.1559
Loa Loa (eye worm) hypothetical protein 0.0145 0.098 0.1065
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0092 0.0406 0.0441
Loa Loa (eye worm) hypothetical protein 0.0059 0.0055 0.006
Loa Loa (eye worm) hypothetical protein 0.0186 0.1424 0.1547
Loa Loa (eye worm) cyclin domain-containing protein 0.0202 0.1596 0.1733
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.2232 0.8741
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0161 0.0152
Loa Loa (eye worm) CDC7 protein kinase 0.0087 0.0358 0.0388
Mycobacterium tuberculosis Probable oxidoreductase 0.0242 0.203 0.2803
Onchocerca volvulus 0.03 0.2657 0.7273
Brugia malayi Variant SH3 domain containing protein 0.0092 0.0412 0.0447
Echinococcus multilocularis dual specificity 0.0119 0.0695 0.08
Loa Loa (eye worm) hypothetical protein 0.0116 0.0667 0.0725
Onchocerca volvulus 0.0106 0.0554 0.1393
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.018 0.1355 0.1321
Onchocerca volvulus 0.0087 0.0358 0.0845
Brugia malayi Immunoglobulin I-set domain containing protein 0.0092 0.0406 0.0441
Schistosoma mansoni protein kinase 0.0107 0.0564 0.0707
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0077 0.0245 0.0207
Entamoeba histolytica protein kinase, putative 0.029 0.2547 0.7527
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0255 0.217 0.2356
Echinococcus granulosus casein kinase I alpha 0.0106 0.0554 0.0517
Echinococcus multilocularis casein kinase I alpha 0.0106 0.0554 0.0628
Plasmodium falciparum calcium-dependent protein kinase 1 0.0098 0.0473 0.0611
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0125 0.0762 0.0979
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0474 0.0515
Echinococcus multilocularis tyrosine protein kinase otk 0.0092 0.0406 0.0448
Brugia malayi Protein kinase domain containing protein 0.0182 0.1382 0.1501
Brugia malayi Protein kinase domain containing protein 0.0578 0.5657 0.6143
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0293 0.2572 0.2793
Brugia malayi Kinase associated domain 1 family protein 0.0098 0.0472 0.0513
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0255 0.217 0.2599
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0079 0.0267 0.0313
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0098 0.0473 0.0513
Echinococcus multilocularis mitogen activated protein kinase 11 0.0154 0.1078 0.1267
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0083 0.0304 0.0344
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.1669 0.2227
Loa Loa (eye worm) hypothetical protein 0.0134 0.0855 0.0929
Schistosoma mansoni tyrosine kinase 0.0433 0.409 0.556
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0098 0.0473 0.0529
Schistosoma mansoni tyrosine kinase 0.0343 0.312 0.4224
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.2043 0.2742
Echinococcus granulosus serine:threonine protein kinase N2 0.0125 0.076 0.0724
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0061 0.0073 0.0089
Loa Loa (eye worm) hypothetical protein 0.0137 0.0897 0.0974
Giardia lamblia Kinase, CMGC CDK 0.0115 0.0659 0.2594
Schistosoma mansoni hypothetical protein 0.0071 0.0177 0.0174
Echinococcus granulosus tyrosine protein kinase Fps85D 0.039 0.3625 0.36
Schistosoma mansoni notch 0.0071 0.0177 0.0174
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0242 0.203 0.2846
Toxoplasma gondii AGC kinase 0.011 0.0599 0.0794
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0059 0.0055 0.006
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0474 0.0515
Plasmodium vivax glutathione reductase, putative 0.07 0.6964 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0061 0.0067 0.0028
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0064 0.0108 0.0118
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0115 0.0659 0.0716
Echinococcus granulosus serine:threonine protein kinase N2 0.0287 0.2516 0.2487
Echinococcus multilocularis aurora kinase A 0.0141 0.0936 0.1095
Loa Loa (eye worm) hypothetical protein 0.0187 0.1436 0.1559
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0242 0.203 0.2863
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.07 0.6964 1
Echinococcus multilocularis 0.0148 0.1016 0.1192
Trypanosoma cruzi casein kinase, putative 0.0106 0.0554 0.0705
Trypanosoma cruzi casein kinase, putative 0.0106 0.0554 0.0705
Echinococcus granulosus casein kinase I alpha 0.0106 0.0554 0.0517
Echinococcus multilocularis neurogenic locus protein delta 0.0071 0.0177 0.0168
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0087 0.0354 0.0384
Brugia malayi Serine/threonine-protein kinase Pim-3 0.034 0.3087 0.3352
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0064 0.0108 0.0084
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.022 0.1784 0.2128
Trichomonas vaginalis AGC family protein kinase 0.0141 0.0936 0.3548
Echinococcus multilocularis cyclin dependent kinase 1 0.0115 0.0659 0.0756
Entamoeba histolytica protein kinase, putative 0.0141 0.0936 0.2638
Schistosoma mansoni peripheral-type benzodiazepine receptor 0.0282 0.2457 0.3312
Echinococcus multilocularis glutamate synthase 0.0064 0.0108 0.0084
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0433 0.4084 0.4435
Leishmania major NADH dehydrogenase, putative 0.0064 0.0108 0.0059
Echinococcus granulosus cGMP dependent protein kinase 1 0.0131 0.0823 0.0787
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Brugia malayi hypothetical protein 0.0114 0.0643 0.0698
Loa Loa (eye worm) CAMK/PIM protein kinase 0.034 0.3087 0.3352
Onchocerca volvulus 0.0087 0.0358 0.0845
Schistosoma mansoni protein kinase 0.0148 0.1016 0.1328
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0242 0.203 1
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0163 0.1169 0.1379
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Schistosoma mansoni hypothetical protein 0.0071 0.0177 0.0174
Brugia malayi Protein kinase domain containing protein 0.0184 0.1402 0.1522
Entamoeba histolytica protein kinase, putative 0.029 0.2547 0.7527
Onchocerca volvulus 0.0071 0.0177 0.0339
Leishmania major protein kinase A catalytic subunit isoform 2 0.011 0.0599 0.0771
Toxoplasma gondii thioredoxin reductase 0.07 0.6964 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0107 0.0564 0.1422
Loa Loa (eye worm) AGC/PKA protein kinase 0.011 0.0599 0.0651
Entamoeba histolytica protein kinase , putative 0.0141 0.0936 0.2638
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0089 0.0373 0.0444
Loa Loa (eye worm) TK/FER protein kinase 0.039 0.3625 0.3937
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0228 0.0247
Loa Loa (eye worm) RGC/RGC protein kinase 0.0107 0.0564 0.0612
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0659 0.0838
Toxoplasma gondii casein kinase I 0.0106 0.0554 0.0728
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0154 0.1078 0.1415
Toxoplasma gondii histone kinase SNF1, putative 0.0087 0.0354 0.0439
Plasmodium falciparum protein kinase 5 0.0115 0.0659 0.088
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.018 0.1355 0.1471
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0738 0.2754
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.011 0.0599 0.0771
Echinococcus multilocularis nmda type glutamate receptor 0.0061 0.0067 0.0034
Echinococcus multilocularis myosin iiia 0.0083 0.0304 0.0324
Loa Loa (eye worm) hypothetical protein 0.0092 0.0406 0.0441
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0242 0.203 0.2803
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.2074 0.2784
Leishmania major trypanothione reductase 0.07 0.6964 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0354 0.3234 0.3208
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0064 0.0108 0.0084
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0108 0.0574 0.0721
Echinococcus multilocularis protein jagged 1 0.0071 0.0177 0.0168
Schistosoma mansoni cell polarity protein 0.0071 0.0177 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.046 0.4379 0.5957
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Echinococcus granulosus glutamate receptor 2 0.0061 0.0067 0.0028
Giardia lamblia Kinase, CDC7 0.0087 0.0358 0.1174
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0098 0.0473 0.0611
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0069 0.0161 0.0122
Plasmodium falciparum calcium-dependent protein kinase 5 0.0098 0.0473 0.0611
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0183 0.1387 0.1645
Loa Loa (eye worm) hypothetical protein 0.0061 0.0067 0.0073
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0163 0.1169 0.1135
Schistosoma mansoni tyrosine kinase 0.0138 0.0903 0.1173
Loa Loa (eye worm) AUR protein kinase 0.0141 0.0936 0.1017
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0087 0.0354 0.0384
Loa Loa (eye worm) hypothetical protein 0.0086 0.0341 0.037
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0261 0.2232 0.2424
Brugia malayi p70 ribosomal S6 kinase beta 0.0282 0.2454 0.2665
Echinococcus multilocularis raf serine:threonine protein kinase 0.0086 0.0345 0.0373
Echinococcus granulosus neurogenic locus notch protein 4 0.0071 0.0177 0.0138
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0152 0.1052 0.1449
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0064 0.0108 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0599 0.0755
Loa Loa (eye worm) TK protein kinase 0.0281 0.2448 0.2659
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.1866 0.2498
Giardia lamblia Kinase, CMGC MAPK 0.0082 0.0295 0.0879
Loa Loa (eye worm) Notch2 0.0071 0.0177 0.0192
Brugia malayi serine/threonine-protein kinase PAK 7 0.0224 0.1836 0.1994
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0092 0.0412 0.0447
Echinococcus multilocularis dual specificity 0.0135 0.0869 0.1012
Loa Loa (eye worm) hypothetical protein 0.0083 0.0305 0.0332
Brugia malayi Protein kinase c protein 2 0.0112 0.0627 0.0681
Trichomonas vaginalis AGC family protein kinase 0.029 0.2547 1
Brugia malayi EGF-like domain containing protein 0.0098 0.0474 0.0515
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0107 0.0569 0.0714
Trichomonas vaginalis STE family protein kinase 0.0084 0.0319 0.1074
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0159 0.1129 0.1227
Schistosoma mansoni hypothetical protein 0.0108 0.0574 0.0721
Schistosoma mansoni sulfide quinone reductase 0.0064 0.0108 0.0079
Entamoeba histolytica protein kinase, putative 0.0131 0.0824 0.2297
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0079 0.0264 0.0228
Loa Loa (eye worm) hypothetical protein 0.0131 0.0822 0.0893
Brugia malayi Egg laying defective protein 4 0.0131 0.0823 0.0894
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0055 0.006
Trichomonas vaginalis CMGC family protein kinase 0.0082 0.0295 0.0979
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0288 0.0327
Schistosoma mansoni septate junction protein 0.0071 0.0177 0.0174
Echinococcus granulosus atrial natriuretic peptide receptor 0.0061 0.0067 0.0028
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0152 0.1052 0.1017
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0055 0.006
Trichomonas vaginalis AGC family protein kinase 0.0141 0.0936 0.3548
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0105 0.0542 0.0589
Trypanosoma cruzi aurora B kinase, putative 0.0141 0.0936 0.126
Echinococcus multilocularis hemicentin 1 0.0092 0.0406 0.0448
Echinococcus granulosus rho-associated protein kinase 1 0.0314 0.2802 0.2774
Loa Loa (eye worm) TK/FAK protein kinase 0.0539 0.523 0.5679
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0084 0.0319 0.0341
Schistosoma mansoni g1/s-specific cyclin C 0.0407 0.381 0.5174
Brugia malayi protein kinase C3,putative 0.0153 0.1063 0.1154
Echinococcus multilocularis GPCR, family 3, C terminal 0.0105 0.0542 0.0613
Echinococcus multilocularis ephrin type A receptor 4 A 0.0108 0.0575 0.0654
Brugia malayi serine/threonine protein kinase 6 0.0141 0.0936 0.1017
Brugia malayi Protein kinase domain containing protein 0.0433 0.4084 0.4435
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0119 0.0698 0.0662
Plasmodium falciparum NIMA related kinase 1 0.0132 0.0839 0.1141
Brugia malayi Casein kinase II, alpha chain 0.0097 0.0465 0.0505
Echinococcus multilocularis roundabout 2 0.0279 0.2428 0.2915
Trypanosoma cruzi cdc2-related kinase 1 0.0115 0.0659 0.0858
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0196 0.153 0.1661
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0064 0.0108 0.0084
Onchocerca volvulus 0.0108 0.0574 0.1451
Brugia malayi hypothetical protein 0.0131 0.0822 0.0893
Echinococcus multilocularis mitogen activated protein kinase 14 0.0154 0.1078 0.1267
Entamoeba histolytica p21-activated kinase 0.0092 0.0411 0.1045
Brugia malayi EGF-like domain containing protein 0.0071 0.0177 0.0192
Schistosoma mansoni glutamate receptor NMDA 0.0061 0.0067 0.0023
Schistosoma mansoni cell adhesion molecule 0.0059 0.0055 0.0007
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0271 0.0885
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0112 0.0621 0.0584
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0465 0.1661
Loa Loa (eye worm) hypothetical protein 0.0137 0.0897 0.0974
Echinococcus granulosus metabotropic glutamate receptor 2 0.0539 0.5236 0.5218
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0059 0.0055 0.0016
Leishmania major protein kinase, putative 0.0079 0.0264 0.0285
Brugia malayi EGF-like domain containing protein 0.0071 0.0177 0.0192
Entamoeba histolytica PH domain containing protein kinase, putative 0.0118 0.0692 0.1896
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.039 0.3625 0.4374
Entamoeba histolytica protein kinase, putative 0.0069 0.0161 0.0284
Brugia malayi protein unc-22 0.0092 0.0409 0.0444
Echinococcus granulosus nervana 2 0.0119 0.0698 0.0662
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0474 0.0515
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0073 0.02 0.0192
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0061 0.0067 0.0028
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0165 0.1195 0.1298
Echinococcus multilocularis dual specificity 0.0135 0.0869 0.1012
Loa Loa (eye worm) hypothetical protein 0.0296 0.2611 0.2835
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.022 0.1787 0.1754
Onchocerca volvulus 0.0071 0.0177 0.0339
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0389 0.3617 0.3592
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0242 0.203 0.2205
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0196 0.153 0.1496
Entamoeba histolytica protein kinase, putative 0.0063 0.0093 0.0079
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0358 0.123
Giardia lamblia Kinase, CAMK CAMKL 0.0087 0.0354 0.1156
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0242 0.203 0.1999
Echinococcus granulosus c-Jun N-terminal kinases 0.0255 0.217 0.2139
Loa Loa (eye worm) thyroid receptor interactor 0.011 0.0598 0.065
Entamoeba histolytica cell division protein kinase 2, putative 0.0115 0.0659 0.1797
Echinococcus granulosus Immunoglobulin 0.0172 0.1273 0.1239
Brugia malayi Protein kinase domain containing protein 0.0111 0.061 0.0663
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0119 0.0695 0.0856
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0084 0.0319 0.0281
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0152 0.1052 0.1236
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0599 0.0755
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0477 0.456 0.4538
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0228 0.1879 0.1847
Echinococcus granulosus titin 0.0092 0.0409 0.0372
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.022 0.1784 0.1751
Brugia malayi Peroxidasin 0.0092 0.041 0.0445
Schistosoma mansoni cathepsin D (A01 family) 0.0174 0.1291 0.1707
Plasmodium falciparum glutathione reductase 0.0242 0.203 0.2863
Brugia malayi hypothetical protein 0.0108 0.0574 0.0624
Giardia lamblia Kinase, CMGC DYRK 0.0135 0.0869 0.358
Plasmodium falciparum serine/threonine protein kinase KIN 0.0087 0.0354 0.0439
Onchocerca volvulus 0.0131 0.0822 0.2144
Echinococcus granulosus casein kinase I delta 0.0106 0.0554 0.0517
Echinococcus granulosus hypothetical protein 0.0116 0.0667 0.0631
Schistosoma mansoni serine/threonine protein kinase 0.0314 0.2802 0.3787
Trichomonas vaginalis STE family protein kinase 0.0083 0.0304 0.1018
Onchocerca volvulus 0.0098 0.0474 0.117
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0869 0.3278
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0061 0.0067 0.0034
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0204 0.1617 0.1756
Brugia malayi Protein kinase domain containing protein 0.0206 0.164 0.1781
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0163 0.1169 0.1135
Echinococcus multilocularis tyrosine protein kinase HCK 0.0131 0.0824 0.0958
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0165 0.1195 0.1298
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0202 0.1596 0.1899
Brugia malayi Protein kinase domain containing protein 0.0098 0.0474 0.0515
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0064 0.0108 0.0059
Schistosoma mansoni protein kinase 0.0063 0.0093 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0659 0.2438
Echinococcus granulosus NCK adaptor protein 0.0089 0.0373 0.0336
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0578 0.5657 0.6143
Entamoeba histolytica protein kinase, putative 0.0081 0.0288 0.0671
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.011 0.0599 0.0683
Echinococcus granulosus fibropellin Ia 0.0071 0.0177 0.0138
Loa Loa (eye worm) hypothetical protein 0.0131 0.0822 0.0893
Brugia malayi hypothetical protein 0.0131 0.0822 0.0893
Brugia malayi Cyclin C 0.0407 0.381 0.4138
Echinococcus granulosus Glutaredoxin protein 5 0.0119 0.0698 0.0662
Echinococcus multilocularis dual specificity 0.0135 0.0869 0.1012
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Echinococcus multilocularis titin 0.0092 0.0409 0.0452
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0135 0.0869 0.1183
Giardia lamblia Kinase, NEK 0.0132 0.0839 0.3442
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0196 0.153 0.1818
Onchocerca volvulus 0.0186 0.1424 0.3827
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.014 0.0929 0.0894
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.2516 0.3393
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0064 0.0108 0.0069
Echinococcus multilocularis tyrosine protein kinase Blk 0.0183 0.1387 0.1645
Echinococcus granulosus cyclin dependent kinase 0.0115 0.0659 0.0623
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0244 0.2043 0.2219
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0072 0.0193 0.0209
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0064 0.0108 0.0231
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0474 0.0515
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1679 0.6523
Brugia malayi Metabotropic glutamate receptor precursor. 0.0644 0.6364 0.6912
Echinococcus multilocularis cyclin dependent kinase 0.0115 0.0659 0.0756
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0107 0.0569 0.0647
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0131 0.0822 0.0893
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0237 0.197 0.2355
Brugia malayi Protein kinase domain containing protein 0.0098 0.0474 0.0515
Trypanosoma brucei trypanothione reductase 0.07 0.6964 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0242 0.203 0.2846
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0064 0.0108 0.0084
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0063 0.009 0.0051
Trypanosoma cruzi cdc2-related kinase 3 0.0115 0.0659 0.0858
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0215 0.1733 0.1882
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0064 0.0108 0.0084
Echinococcus granulosus mitogen activated protein kinase 14 0.0154 0.1078 0.1043
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0271 0.0304
Echinococcus multilocularis casein kinase I delta 0.0106 0.0554 0.0628
Loa Loa (eye worm) AUR protein kinase 0.0141 0.0936 0.1017
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.2232 0.3003
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0621 0.2284
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Schistosoma mansoni serine/threonine kinase 0.021 0.1679 0.2241
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0084 0.0319 0.0281
Loa Loa (eye worm) TK protein kinase 0.0277 0.2401 0.2607
Schistosoma mansoni ste20-related kinase 0.0198 0.1556 0.2072
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.011 0.0599 0.0794
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0159 0.1126 0.1223
Plasmodium falciparum calcium-dependent protein kinase 4 0.0098 0.0473 0.0611
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.022 0.1784 0.1751
Brugia malayi metabotropic glutamate receptor type 2 0.0314 0.2802 0.3043
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Entamoeba histolytica PH domain containing protein kinase, putative 0.0118 0.0692 0.1896
Brugia malayi EGF-like domain containing protein 0.0071 0.0177 0.0192
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0055 0.006
Echinococcus granulosus neurogenic locus notch protein 0.0071 0.0177 0.0138
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0064 0.0108 0.0084
Leishmania major protein kinase, putative 0.0141 0.0936 0.126
Schistosoma mansoni nephrin 0.0232 0.1915 0.2565
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0465 0.1661
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0125 0.0762 0.0725
Brugia malayi Guanylyl cyclase protein 23 0.0107 0.0564 0.0612
Schistosoma mansoni growth factor receptor-bound protein 0.0089 0.0373 0.0444
Echinococcus multilocularis tyrosine protein kinase Abl 0.0135 0.087 0.1014
Echinococcus granulosus CDC7 cell division cycle 7 0.0087 0.0358 0.032
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0345 0.0405
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0082 0.0295 0.033
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0059 0.0055 0.006
Schistosoma mansoni sulfide quinone reductase 0.0064 0.0108 0.0079
Schistosoma mansoni tyrosine kinase 0.0343 0.312 0.4224
Echinococcus multilocularis protein tyrosine kinase 0.0533 0.5167 0.6256
Schistosoma mansoni tyrosine kinase 0.059 0.5779 0.7883
Trypanosoma cruzi Protein kinase B 0.016 0.1145 0.1562
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0354 0.0417
Trypanosoma cruzi NADH dehydrogenase, putative 0.0064 0.0108 0.0059
Loa Loa (eye worm) programmed cell death 8 0.0064 0.0108 0.0118
Loa Loa (eye worm) hypothetical protein 0.0131 0.0822 0.0893
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0135 0.0869 0.1109
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0227 0.1866 0.1834
Leishmania major hypothetical protein, conserved 0.0064 0.0108 0.0059
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Leishmania major protein kinase, putative 0.0083 0.0304 0.0344
Loa Loa (eye worm) hypothetical protein 0.02 0.1576 0.1711
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.011 0.0599 0.0562
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0064 0.0108 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0295 0.0336
Onchocerca volvulus 0.0092 0.0409 0.0989
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0115 0.0659 0.0858
Brugia malayi putative serine/threonine kinase SADA gamma 0.0087 0.0354 0.0384
Schistosoma mansoni tyrosine kinase 0.0135 0.087 0.1128
Echinococcus multilocularis hemicentin 1 0.0092 0.0406 0.0448
Echinococcus multilocularis nervana 2 0.0119 0.0698 0.0804
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0632 0.0801
Echinococcus multilocularis Glutaredoxin protein 5 0.0119 0.0698 0.0804
Giardia lamblia Kinase, NEK 0.0132 0.0839 0.3442
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0242 0.2029 0.2427
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.1669 0.2227
Echinococcus multilocularis neurogenic locus notch protein 4 0.0071 0.0177 0.0168
Echinococcus granulosus nephrin 0.0059 0.0055 0.0016
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.2232 0.8741
Schistosoma mansoni vam6/vps39 related 0.0108 0.0574 0.0721
Brugia malayi EGF-like domain containing protein 0.0071 0.0177 0.0192
Schistosoma mansoni notch 0.0071 0.0177 0.0174
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0271 0.0885
Schistosoma mansoni hypothetical protein 0.0059 0.0055 0.0007
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0064 0.0108 0.0084
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0474 0.0515
Onchocerca volvulus 0.0282 0.2457 0.6715
Schistosoma mansoni serine/threonine protein kinase 0.0215 0.1733 0.2316
Entamoeba histolytica protein kinase, putative 0.0125 0.0762 0.2108
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.0826 0.1067
Plasmodium falciparum protein kinase, putative 0.0079 0.0264 0.0309
Loa Loa (eye worm) hypothetical protein 0.0087 0.0354 0.0384
Brugia malayi EGF-like domain containing protein 0.0071 0.0177 0.0192
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.022 0.1784 0.2128
Echinococcus multilocularis dual specificity protein kinase clk2 0.0149 0.1021 0.1198
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0064 0.0108 0.0231
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0064 0.0108 0.0118
Echinococcus granulosus nmda type glutamate receptor 0.0061 0.0067 0.0028
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0092 0.0412 0.0497
Loa Loa (eye worm) hypothetical protein 0.0061 0.0067 0.0073
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0154 0.1078 0.1465
Echinococcus multilocularis growth factor receptor bound protein 2 0.0089 0.0373 0.0408
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0082 0.0295 0.033
Onchocerca volvulus 0.0131 0.0822 0.2144
Echinococcus multilocularis hypothetical protein 0.0098 0.0472 0.0528
Loa Loa (eye worm) hypothetical protein 0.0178 0.1332 0.1446
Giardia lamblia Kinase, NEK 0.0132 0.0839 0.3442
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0083 0.0304 0.072
Brugia malayi GCC2 and GCC3 family protein 0.0201 0.1585 0.1722
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0223 0.1823 0.1791
Toxoplasma gondii NADPH-glutathione reductase 0.0242 0.203 0.2863
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.011 0.0599 0.0562
Echinococcus multilocularis neurogenic locus notch protein 0.0071 0.0177 0.0168
Schistosoma mansoni notch 0.0071 0.0177 0.0174
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0082 0.0295 0.032
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0194 0.151 0.1794
Trichomonas vaginalis AGC family protein kinase 0.0132 0.0839 0.316
Schistosoma mansoni glutamate synthase 0.0064 0.0108 0.0079
Brugia malayi hypothetical protein 0.0131 0.0822 0.0893
Trichomonas vaginalis AGC family protein kinase 0.0182 0.1382 0.5333
Schistosoma mansoni protein kinase C mu 0.021 0.1685 0.225
Onchocerca volvulus 0.0131 0.0822 0.2144
Echinococcus granulosus cGMP dependent protein kinase 1 0.0131 0.0823 0.0787
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0793 0.797 0.9676
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0209 0.1669 0.1636
Loa Loa (eye worm) hypothetical protein 0.0114 0.0649 0.0705
Echinococcus multilocularis neurogenic locus notch protein 0.0071 0.0177 0.0168
Toxoplasma gondii AGC kinase 0.0282 0.2454 0.3476
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0154 0.1078 0.1465
Loa Loa (eye worm) hypothetical protein 0.0187 0.1436 0.1559
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0448 0.4253 0.423
Trichomonas vaginalis CK1 family protein kinase 0.0106 0.0554 0.2016
Entamoeba histolytica protein kinase, putative 0.0079 0.0271 0.062
Mycobacterium ulcerans hypothetical protein 0.0098 0.0469 0.1537
Entamoeba histolytica protein kinase, putative 0.0119 0.0695 0.1905
Trypanosoma cruzi cdc2-related kinase 1 0.0115 0.0659 0.0858
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0242 0.203 0.2863
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0178 0.1336 0.145
Echinococcus granulosus cGMP dependent protein kinase 0.0131 0.0823 0.0787
Brugia malayi Immunoglobulin I-set domain containing protein 0.0092 0.0406 0.0441
Echinococcus granulosus hemicentin 1 0.0092 0.0406 0.0369
Loa Loa (eye worm) hypothetical protein 0.0108 0.0574 0.0624
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0064 0.0108 0.0231
Loa Loa (eye worm) hypothetical protein 0.0061 0.0067 0.0073
Brugia malayi Protein kinase domain containing protein 0.0187 0.1437 0.1561
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0242 0.203 0.2846
Trichomonas vaginalis mercuric reductase, putative 0.0242 0.203 0.793
Brugia malayi Protein kinase domain containing protein 0.0277 0.2401 0.2607
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0209 0.1669 0.1988
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.2232 0.8741
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0261 0.2232 0.3139
Plasmodium vivax protein kinase Crk2 0.0115 0.0659 0.088
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0079 0.0267 0.0313
Toxoplasma gondii rhoptry neck protein RON9 0.0131 0.0822 0.1117
Loa Loa (eye worm) hypothetical protein 0.0061 0.0067 0.0073
Echinococcus multilocularis expressed protein 0.0081 0.0288 0.0304
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0209 0.1669 0.1988
Echinococcus multilocularis tyrosine protein kinase Fyn 0.022 0.1784 0.2128
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0098 0.0473 0.0611
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.011 0.0599 0.0716
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.014 0.0929 0.1086
Echinococcus multilocularis cyclin dependent kinase 5 0.0115 0.0659 0.0756
Brugia malayi Protein kinase domain containing protein 0.0098 0.0474 0.0515
Brugia malayi hypothetical protein 0.0131 0.0822 0.0893
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0732 0.7317 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0242 0.203 0.2846
Schistosoma mansoni ephrin receptor 0.0108 0.0575 0.0722
Trichomonas vaginalis AGC family protein kinase 0.029 0.2547 1
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0271 0.0885
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0072 0.019 0.0206
Loa Loa (eye worm) AGC/PKN protein kinase 0.0287 0.2516 0.2732
Brugia malayi protein-tyrosine kinase 0.0183 0.1387 0.1507
Schistosoma mansoni protein kinase 0.0419 0.3932 0.5341
Echinococcus granulosus tyrosine protein kinase shark 0.0304 0.2691 0.2663
Echinococcus granulosus tyrosine protein kinase Fyn 0.022 0.1784 0.1751
Echinococcus granulosus tyrosine kinase 0.0107 0.0564 0.0527
Onchocerca volvulus 0.0131 0.0822 0.2144
Echinococcus granulosus C type lectin domian containing protein 0.0131 0.0822 0.0786
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.011 0.0599 0.0771
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0354 0.0417
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.009 0.0389 0.0352
Echinococcus granulosus protein kinase C gamma type 0.0202 0.1594 0.1561
Loa Loa (eye worm) hypothetical protein 0.0098 0.0473 0.0513
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0869 0.3278
Schistosoma mansoni cell adhesion molecule 0.0235 0.1949 0.2613
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Giardia lamblia Kinase, CMGC CLK 0.0149 0.1021 0.4297
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0059 0.0051 0.0055
Trypanosoma brucei protein kinase, putative 0.0079 0.0264 0.0228
Giardia lamblia NADH oxidase lateral transfer candidate 0.0242 0.203 0.9048
Echinococcus multilocularis mitogen activated protein kinase 0.0082 0.0295 0.0312
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0063 0.009 0.0062
Echinococcus multilocularis 0.0116 0.0667 0.0766
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0695 0.0887
Echinococcus multilocularis serine:threonine protein kinase 38 0.0163 0.1169 0.1379
Echinococcus multilocularis serine:threonine protein kinase 3 0.0248 0.2093 0.2505
Trypanosoma brucei protein kinase, putative 0.0082 0.0295 0.0272
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.1866 0.2498
Trypanosoma cruzi casein kinase II, putative 0.0097 0.0465 0.0577
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0321 0.2873 0.312
Echinococcus multilocularis tyrosine kinase 0.0107 0.0564 0.064
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0321 0.2873 0.312
Echinococcus granulosus raf serine:threonine protein kinase 0.0086 0.0345 0.0307
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0098 0.0473 0.0513
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0473 0.0581
Loa Loa (eye worm) hypothetical protein 0.0223 0.1823 0.1979
Loa Loa (eye worm) thioredoxin reductase 0.07 0.6964 0.7562
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0107 0.0569 0.0647
Echinococcus granulosus expressed protein 0.0081 0.0288 0.025
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.011 0.0599 0.0716
Loa Loa (eye worm) hypothetical protein 0.0264 0.2266 0.246
Echinococcus granulosus protein kinase c epsilon type 0.0204 0.1617 0.1584
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0064 0.0108 0.0231
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0149 0.1021 0.1404
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0087 0.0354 0.0439
Plasmodium falciparum calcium-dependent protein kinase 2 0.0098 0.0473 0.0611
Echinococcus multilocularis roundabout 2 0.0107 0.0569 0.0647
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0064 0.0108 0.0118
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0083 0.0304 0.0344
Schistosoma mansoni nephrin 0.0107 0.0569 0.0714
Brugia malayi Protein kinase domain containing protein 0.0119 0.0695 0.0755
Echinococcus granulosus thioredoxin glutathione reductase 0.07 0.6964 0.6952
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0132 0.0839 0.1141
Brugia malayi Protein kinase domain containing protein 0.029 0.2547 0.2766
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0064 0.0108 0.0231
Trichomonas vaginalis CMGC family protein kinase 0.0125 0.0762 0.2849
Schistosoma mansoni neuroglian 0.0107 0.0569 0.0714
Loa Loa (eye worm) hypothetical protein 0.0061 0.0067 0.0073
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0097 0.0465 0.0505
Brugia malayi TspO/MBR family protein 0.0282 0.2457 0.2669
Trichomonas vaginalis STE family protein kinase 0.0084 0.0319 0.1074
Echinococcus multilocularis casein kinase I alpha 0.0106 0.0554 0.0628
Plasmodium vivax serine/threonine kinase-1, putative 0.0149 0.1021 0.1404
Entamoeba histolytica protein kinase domain containing protein 0.0125 0.0762 0.2108
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0064 0.0108 0.0124
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0554 0.0693
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0354 0.0417
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.1617 0.2156
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0907 0.9208 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.022 0.1784 0.1751
Schistosoma mansoni protein kinase 0.0141 0.0936 0.1219
Loa Loa (eye worm) hypothetical protein 0.0092 0.0406 0.0441
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.0826 0.1067
Echinococcus multilocularis tyrosine protein kinase 0.0277 0.2401 0.2881
Schistosoma mansoni serine/threonine kinase 0.0163 0.1169 0.154
Brugia malayi Delta serrate ligand family protein 0.0071 0.0177 0.0192
Echinococcus multilocularis protein kinase shaggy 0.0125 0.0762 0.0881
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0242 0.203 1
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0869 0.1126
Brugia malayi RhoGAP domain containing protein 0.0092 0.0412 0.0447
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0092 0.0406 0.049
Onchocerca volvulus 0.0125 0.0762 0.1974
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0354 0.0417
Brugia malayi Protein kinase domain containing protein 0.0187 0.1428 0.1551
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0098 0.0473 0.0611
Plasmodium vivax apical sushi protein, putative 0.0131 0.0822 0.1117
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0087 0.0354 0.0415
Echinococcus granulosus serine/threonine protein kinase 0.016 0.1145 0.111
Echinococcus granulosus aurora kinase A 0.0141 0.0936 0.0901
Schistosoma mansoni protein kinase 0.0084 0.0319 0.0369
Giardia lamblia High cysteine protein 0.0071 0.0177 0.0322
Brugia malayi hypothetical protein 0.0098 0.0474 0.0515
Loa Loa (eye worm) hypothetical protein 0.0069 0.0154 0.0168
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0237 0.197 0.1938
Schistosoma mansoni notch 0.0071 0.0177 0.0174
Loa Loa (eye worm) hypothetical protein 0.0134 0.0855 0.0929
Echinococcus granulosus protein jagged 2 0.0071 0.0177 0.0138
Trichomonas vaginalis glutamate synthase, putative 0.0064 0.0108 0.0231
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0242 0.203 0.2803
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0125 0.0762 0.0827
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0108 0.0574 0.0537
Schistosoma mansoni metabotropic glutamate receptor 0.0539 0.5236 0.7137
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.2232 0.8741
Trypanosoma cruzi NADH dehydrogenase, putative 0.0064 0.0108 0.0059
Loa Loa (eye worm) hypothetical protein 0.0131 0.0822 0.0893
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0659 0.2438
Loa Loa (eye worm) CAMK/PIM protein kinase 0.034 0.3087 0.3352
Brugia malayi Immunoglobulin I-set domain containing protein 0.0107 0.0569 0.0618
Echinococcus granulosus cyclin dependent kinase 19 0.0293 0.2572 0.2543
Giardia lamblia Kinase, AGC PKA 0.0152 0.1052 0.4443
Schistosoma mansoni ephrin receptor 0.0061 0.0073 0.0031
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0141 0.0936 0.1281
Brugia malayi notch-like transmembrane receptor 0.0071 0.0177 0.0192
Brugia malayi Variant SH3 domain containing protein 0.0089 0.0373 0.0405
Schistosoma mansoni protein kinase 0.0097 0.0465 0.057
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0135 0.087 0.1128
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0244 0.2043 0.2445
Plasmodium vivax protein kinase, putative 0.0061 0.0067 0.0024
Echinococcus granulosus lachesin 0.0092 0.0406 0.0369
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0146 0.0992 0.1077
Loa Loa (eye worm) RGC/RGC protein kinase 0.0107 0.0564 0.0612
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0071 0.0177 0.0192
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0473 0.1691
Onchocerca volvulus Serine\/threonine kinase homolog 0.0261 0.2232 0.6086
Echinococcus multilocularis glutamate receptor 2 0.0061 0.0067 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0141 0.0936 0.3548
Plasmodium vivax ferrodoxin reductase, putative 0.0064 0.0108 0.0084
Echinococcus multilocularis lachesin 0.0092 0.0406 0.0448
Brugia malayi probable protein kinase 0.0256 0.2176 0.2364
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0064 0.0108 0.0118
Schistosoma mansoni tyrosine kinase 0.0533 0.5167 0.7041
Loa Loa (eye worm) AGC/AKT protein kinase 0.029 0.2547 0.2766
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.021 0.1679 0.1823
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0183 0.1387 0.1354
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0333 0.3013 0.3272
Echinococcus multilocularis 0.0167 0.1217 0.1438
Echinococcus multilocularis Immunoglobulin 0.0172 0.1273 0.1505
Onchocerca volvulus Tyrosine kinase homolog 0.0391 0.3632 1
Schistosoma mansoni protein kinase 0.0256 0.2176 0.2926
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.034 0.3087 0.306
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0055 0.006
Schistosoma mansoni cathepsin D (A01 family) 0.0174 0.1291 0.1707
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0098 0.0474 0.053
Loa Loa (eye worm) protein kinase domain-containing protein 0.0206 0.164 0.1781
Entamoeba histolytica protein kinase, putative 0.0141 0.0936 0.2638
Trypanosoma brucei Casein kinase II 0.0097 0.0465 0.052
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0061 0.0067 0.0034
Plasmodium falciparum serine/threonine protein kinase, putative 0.0141 0.0936 0.1281
Treponema pallidum NADH oxidase 0.0242 0.203 1
Echinococcus granulosus defective proboscis extension response 0.0172 0.1273 0.1239
Echinococcus granulosus tyrosine protein kinase Lyn 0.0252 0.2137 0.2106
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0098 0.0473 0.0611
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0115 0.0659 0.0716
Schistosoma mansoni tyrosine kinase 0.0135 0.087 0.1128
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0069 0.0161 0.0149
Trypanosoma cruzi casein kinase, putative 0.0106 0.0554 0.0705
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.038 0.3519 0.4246
Echinococcus multilocularis mitogen activated protein kinase 3 0.0082 0.0295 0.0312
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Schistosoma mansoni notch 0.0071 0.0177 0.0174
Echinococcus granulosus tyrosine kinase 0.0183 0.1387 0.1354
Brugia malayi hypothetical protein 0.0131 0.0822 0.0893
Loa Loa (eye worm) TK/EPH protein kinase 0.0125 0.0758 0.0823
Echinococcus granulosus cyclin dependent kinase 1 0.0115 0.0659 0.0623
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0064 0.0108 0.0084
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0098 0.0473 0.0435
Brugia malayi Temporarily assigned gene name protein 59 0.0108 0.0574 0.0624
Leishmania major casein kinase, putative 0.0106 0.0554 0.0705
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0122 0.0734 0.0967
Onchocerca volvulus 0.0064 0.0108 0.0148
Giardia lamblia Kinase, CAMK CAMKL 0.0087 0.0354 0.1156
Onchocerca volvulus 0.0178 0.1332 0.3568
Schistosoma mansoni serine/threonine protein kinase 0.018 0.1355 0.1795
Echinococcus multilocularis tyrosine protein kinase Src42A 0.022 0.1784 0.2128
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0059 0.0055 0.006
Brugia malayi cell division control protein 2 homolog 0.0115 0.0659 0.0716
Loa Loa (eye worm) hypothetical protein 0.0174 0.129 0.14
Schistosoma mansoni protein kinase 0.0187 0.1428 0.1895
Echinococcus multilocularis serine:threonine protein kinase 0.0111 0.061 0.0697
Echinococcus granulosus epidermal growth factor receptor 0.0389 0.3617 0.3592
Trypanosoma cruzi trypanothione reductase, putative 0.07 0.6964 1
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0064 0.0108 0.0084
Entamoeba histolytica protein kinase, putative 0.0069 0.0161 0.0284
Trypanosoma brucei polo-like protein kinase 0.0261 0.2232 0.3098
Echinococcus granulosus growth factor receptor bound protein 2 0.0091 0.0394 0.0356
Trypanosoma brucei SNF1-related protein kinases, putative 0.0087 0.0354 0.0358
Echinococcus multilocularis tyrosine protein kinase Srms 0.0183 0.1387 0.1645
Giardia lamblia Kinase, CMGC CK2 0.0097 0.0465 0.168
Echinococcus multilocularis transfer RNA-Phe 0.0059 0.0055 0.002
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0061 0.0067 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Plasmodium falciparum casein kinase 2, alpha subunit 0.0097 0.0465 0.06
Onchocerca volvulus 0.0098 0.0474 0.117
Brugia malayi glutamate synthase 0.0064 0.0108 0.0118
Loa Loa (eye worm) hypothetical protein 0.0092 0.0406 0.0441
Echinococcus granulosus protein jagged 1 0.0071 0.0177 0.0138
Echinococcus multilocularis tyrosine protein kinase shark 0.0304 0.2691 0.3236
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.011 0.0599 0.0683
Echinococcus granulosus serine:threonine protein kinase 0.0111 0.061 0.0574
Echinococcus multilocularis activin receptor type 0.0079 0.0264 0.0275
Entamoeba histolytica protein kinase 2, putative 0.0152 0.1052 0.2989
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0064 0.0108 0.0124
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0237 0.197 0.2355
Entamoeba histolytica protein kinase, putative 0.0135 0.0869 0.2433
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0566 0.5526 0.6002
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0141 0.0936 0.1095
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0055 0.006
Loa Loa (eye worm) AGC/PKA protein kinase 0.011 0.0599 0.0651
Mycobacterium ulcerans tryptophan-rich sensory protein 0.0282 0.2457 1
Plasmodium falciparum thioredoxin reductase 0.0242 0.203 0.2863
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0163 0.1169 0.1379
Trichomonas vaginalis AGC family protein kinase 0.011 0.0599 0.2198
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0148 0.1016 0.1103
Echinococcus granulosus glutamate receptor 2 0.0061 0.0067 0.0028
Loa Loa (eye worm) hypothetical protein 0.0061 0.007 0.0076
Brugia malayi P38 map kinase family protein 2 0.0154 0.1078 0.1171
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Echinococcus granulosus neurogenic locus protein delta 0.0071 0.0177 0.0138
Echinococcus multilocularis calcium dependent protein kinase 0.0065 0.0119 0.0097
Brugia malayi C1-like domain containing protein 0.021 0.1685 0.183
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0085 0.0331 0.0801
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0064 0.0108 0.0231
Entamoeba histolytica protein kinase, putative 0.0084 0.0319 0.0763
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0215 0.1733 0.2067
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0107 0.0569 0.0647
Trichomonas vaginalis AGC family protein kinase 0.029 0.2547 1
Trichomonas vaginalis glutathione reductase, putative 0.0242 0.203 0.793
Toxoplasma gondii EGF family domain-containing protein 0.0071 0.0177 0.0182
Schistosoma mansoni cell adhesion molecule 0.0092 0.0406 0.049
Echinococcus multilocularis rac serine:threonine kinase 0.016 0.1145 0.1349
Loa Loa (eye worm) glutamate receptor 0.0644 0.6364 0.6912
Echinococcus multilocularis slit 2 protein 0.0098 0.0474 0.053
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0244 0.2043 0.2012
Schistosoma mansoni serine/threonine protein kinase 0.0293 0.2572 0.347
Brugia malayi Thioredoxin reductase 0.07 0.6964 0.7562
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.011 0.0599 0.0562
Onchocerca volvulus Serine\/threonine kinase homolog 0.0159 0.1129 0.3003
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0131 0.0823 0.0957
Loa Loa (eye worm) hypothetical protein 0.0173 0.1276 0.1386
Echinococcus granulosus contactin 0.0107 0.0569 0.0532
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.011 0.0599 0.0683
Brugia malayi Muscle positioning protein 4 0.0071 0.0177 0.0192
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0064 0.0108 0.0059
Echinococcus granulosus casein kinase i 0.0106 0.0554 0.0517
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0392 0.3641 0.4394
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0659 0.2438
Brugia malayi Protein kinase domain containing protein 0.0578 0.5657 0.6143
Schistosoma mansoni rap gtpase-activating protein 0.0108 0.0574 0.0721
Schistosoma mansoni protein kinase 0.0354 0.3234 0.4382
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0064 0.0108 0.0124
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0087 0.0354 0.0358
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0149 0.1021 0.1383
Loa Loa (eye worm) hypothetical protein 0.0131 0.0822 0.0893
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0474 0.0515
Trichomonas vaginalis CMGC family protein kinase 0.0082 0.0295 0.0979
Echinococcus multilocularis mitogen activated protein kinase 11 0.0154 0.1078 0.1267
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0064 0.0108 0.0059
Echinococcus granulosus Protein kinase C brain isozyme 0.0242 0.2029 0.1997
Loa Loa (eye worm) hypothetical protein 0.0444 0.4206 0.4568
Trichomonas vaginalis glutamate synthase, putative 0.0064 0.0108 0.0231
Echinococcus granulosus neuroglian 0.0107 0.0569 0.0532
Echinococcus multilocularis expressed conserved protein 0.0131 0.0823 0.0957
Trichomonas vaginalis STE family protein kinase 0.0063 0.0093 0.0172
Brugia malayi Variant SH3 domain containing protein 0.0062 0.0083 0.009
Echinococcus granulosus tyrosine protein kinase HCK 0.0131 0.0824 0.0788
Echinococcus multilocularis cyclin dependent kinase 1 0.0115 0.0659 0.0756
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0061 0.0067 0.0028
Loa Loa (eye worm) hypothetical protein 0.0064 0.0108 0.0118
Loa Loa (eye worm) projectin 0.0059 0.0055 0.006
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0465 0.1661
Echinococcus multilocularis translocator protein 0.0282 0.2457 0.295
Brugia malayi Calcium binding EGF domain containing protein 0.0071 0.0177 0.0192
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Entamoeba histolytica protein kinase, putative 0.0098 0.0473 0.123
Echinococcus granulosus roundabout 2 0.0107 0.0569 0.0532
Echinococcus multilocularis roundabout 2 0.0107 0.0569 0.0647
Loa Loa (eye worm) hypothetical protein 0.011 0.0599 0.0651
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0082 0.0295 0.0354
Schistosoma mansoni hemicentin 0.0059 0.0055 0.0007
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0242 0.203 0.2846
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Loa Loa (eye worm) casein kinase 0.0173 0.1286 0.1397
Schistosoma mansoni septate junction protein 0.0092 0.0406 0.049
Brugia malayi Protein kinase domain containing protein 0.0098 0.0474 0.0515
Echinococcus multilocularis PAK box P21 Rho binding 0.0063 0.0093 0.0066
Echinococcus granulosus epidermal growth factor receptor 0.059 0.5779 0.5762
Trypanosoma cruzi cdc2-related kinase 3 0.0115 0.0659 0.0858
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0152 0.1052 0.1449
Echinococcus granulosus titin 0.0092 0.0409 0.0372
Schistosoma mansoni titin 0.0092 0.0409 0.0494
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.034 0.3087 0.3718
Loa Loa (eye worm) hypothetical protein 0.0092 0.0406 0.0441
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0159 0.1129 0.1095
Brugia malayi Protein kinase domain containing protein 0.0159 0.1129 0.1227
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0098 0.0473 0.0435
Schistosoma mansoni titin 0.0059 0.0055 0.0007
Brugia malayi Immunoglobulin I-set domain containing protein 0.0092 0.0406 0.0441
Brugia malayi Cyclin, N-terminal domain containing protein 0.0202 0.1596 0.1733
Echinococcus multilocularis c src tyrosine kinase 0.0135 0.087 0.1014
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0869 0.3278
Trypanosoma cruzi hypothetical protein, conserved 0.0064 0.0108 0.0059
Brugia malayi Immunoglobulin I-set domain containing protein 0.0092 0.0406 0.0441
Onchocerca volvulus 0.0281 0.2448 0.6689
Onchocerca volvulus 0.0131 0.0822 0.2144
Echinococcus granulosus c src tyrosine kinase 0.0135 0.087 0.0834
Echinococcus granulosus netrin receptor unc 5 0.0075 0.0228 0.0189
Giardia lamblia Kinase, AGC PKA 0.011 0.0599 0.2311
Echinococcus multilocularis epidermal growth factor receptor 0.0389 0.3617 0.4364
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.2232 0.8741
Brugia malayi Protein kinase domain containing protein 0.0163 0.1169 0.127
Loa Loa (eye worm) hypothetical protein 0.0098 0.0474 0.0515
Echinococcus granulosus twitchin 0.0249 0.2106 0.2075
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0079 0.0271 0.0233
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.022 0.1784 0.2128
Plasmodium vivax glycogen synthase kinase 3, putative 0.0125 0.0762 0.1029
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0064 0.0108 0.0059
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0139 0.0912 0.1064
Loa Loa (eye worm) TK/INSR protein kinase 0.0433 0.409 0.4442
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Toxoplasma gondii selenide, water dikinase 0.0064 0.0108 0.0084
Entamoeba histolytica protein kinase domain containing protein 0.0135 0.0869 0.2433
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0087 0.0354 0.0415
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0227 0.1866 0.2229
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0092 0.0412 0.0374
Brugia malayi Bromodomain containing protein 0.0073 0.0199 0.0216
Trichomonas vaginalis AGC family protein kinase 0.029 0.2547 1
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.0823 0.1063
Echinococcus granulosus casein kinase ii subunit alpha 0.0097 0.0465 0.0428
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Echinococcus multilocularis calcium activated potassium channel 0.0131 0.0826 0.096
Loa Loa (eye worm) TK/ALK protein kinase 0.0274 0.2367 0.257
Loa Loa (eye worm) TK/ABL protein kinase 0.0098 0.0474 0.0515
Brugia malayi Fes/CIP4 homology domain containing protein 0.011 0.0598 0.065
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0141 0.0936 0.2638
Echinococcus multilocularis thioredoxin glutathione reductase 0.07 0.6964 0.8447
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0242 0.203 0.2724
Onchocerca volvulus 0.0071 0.0185 0.0362
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0242 0.203 0.2846
Brugia malayi STE20-like kinase MST 0.0248 0.2093 0.2273
Echinococcus granulosus tyrosine protein kinase 0.0277 0.2401 0.2371
Loa Loa (eye worm) hypothetical protein 0.0344 0.3128 0.3397
Echinococcus multilocularis insulin receptor 0.0433 0.409 0.4942
Brugia malayi Protein kinase domain containing protein 0.0079 0.0271 0.0295
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0477 0.456 0.5515
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0087 0.0354 0.0415
Echinococcus granulosus MAP kinase activated protein kinase 2 0.038 0.3519 0.3494
Echinococcus multilocularis protein jagged 1 0.0071 0.0177 0.0168
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0172 0.1273 0.1682
Entamoeba histolytica thioredoxin reductase, putative 0.0064 0.0108 0.0124
Echinococcus multilocularis serine:threonine protein kinase N2 0.0163 0.1169 0.1379
Plasmodium falciparum thioredoxin reductase 0.07 0.6964 1
Echinococcus multilocularis twitchin 0.0077 0.0247 0.0253
Entamoeba histolytica protein kinase domain containing protein 0.0141 0.0936 0.2638
Schistosoma mansoni tyrosine kinase 0.022 0.1784 0.2385
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0465 0.1661
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0578 0.5657 0.6143
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0069 0.0161 0.0149
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0069 0.0161 0.0122
Onchocerca volvulus Poor gastrulation protein homolog 0.0105 0.0542 0.136
Echinococcus granulosus calcium dependent protein kinase 0.0065 0.0119 0.008
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0248 0.2093 0.2273
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Onchocerca volvulus 0.0071 0.0177 0.0339
Schistosoma mansoni protein kinase 0.0419 0.3932 0.5341
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0936 0.1219
Brugia malayi Cadherin domain containing protein 0.0071 0.0177 0.0192
Loa Loa (eye worm) hypothetical protein 0.0282 0.2457 0.2669
Schistosoma mansoni protein kinase 0.0079 0.0264 0.0294
Plasmodium vivax calcium-dependent protein kinase, putative 0.0098 0.0473 0.0611
Echinococcus granulosus casein kinase I delta 0.0106 0.0554 0.0517
Plasmodium vivax serine/threonine protein kinase, putative 0.0081 0.0288 0.0344
Echinococcus granulosus calcium activated potassium channel 0.0131 0.0826 0.079
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0079 0.0264 0.0285
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0064 0.0108 0.0084
Echinococcus multilocularis serine:threonine protein kinase 0.0111 0.061 0.0697
Trichomonas vaginalis AGC family protein kinase 0.029 0.2547 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0064 0.0108 0.0084
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0055 0.006
Toxoplasma gondii aurora kinase 0.0141 0.0936 0.1281
Echinococcus granulosus nervana 2 0.0119 0.0698 0.0662
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0242 0.203 1
Loa Loa (eye worm) SRC-1 0.022 0.1784 0.1937
Brugia malayi Calcium binding EGF domain containing protein 0.0071 0.0177 0.0192
Loa Loa (eye worm) CAMK/PKD protein kinase 0.021 0.1685 0.183
Onchocerca volvulus 0.0131 0.0822 0.2144
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0392 0.3641 0.3616
Trichomonas vaginalis STE family protein kinase 0.0084 0.0319 0.1074
Schistosoma mansoni serine/threonine protein kinase 0.038 0.3519 0.4774
Loa Loa (eye worm) hypothetical protein 0.0089 0.0373 0.0405
Onchocerca volvulus 0.0131 0.0822 0.2144
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0071 0.0177 0.0174
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0111 0.061 0.0663
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Giardia lamblia Aurora kinase 0.0141 0.0936 0.3898
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0082 0.0295 0.033
Loa Loa (eye worm) glutamate receptor 0.0253 0.2148 0.2333
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Echinococcus multilocularis protein jagged 2 0.0071 0.0177 0.0168
Brugia malayi Serine/threonine-protein kinase SULU 0.0215 0.1733 0.1882
Echinococcus multilocularis fat cadherin tumor suppressor 0.0071 0.0177 0.0168
Schistosoma mansoni tyrosine kinase 0.0433 0.409 0.556
Brugia malayi map kinase activated protein kinase protein 2 0.038 0.3519 0.3822
Echinococcus granulosus c4b binding protein beta chain 0.0131 0.0822 0.0786
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0092 0.0406 0.0441
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0098 0.0473 0.0435
Schistosoma mansoni hypothetical protein 0.0071 0.0177 0.0174
Loa Loa (eye worm) CAMK/PKD protein kinase 0.017 0.1251 0.1359
Entamoeba histolytica protein kinase, putative 0.0099 0.0486 0.127
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0149 0.1021 0.1383
Loa Loa (eye worm) TK protein kinase 0.0183 0.1387 0.1507
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0064 0.0108 0.0059
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0358 0.0423
Leishmania major hypothetical protein, conserved 0.0064 0.0108 0.0059
Echinococcus multilocularis Immunoglobulin 0.0172 0.1273 0.1505
Echinococcus multilocularis protein kinase c iota type 0.0283 0.2465 0.2959
Trypanosoma brucei aurora B kinase 0.0141 0.0936 0.1208
Loa Loa (eye worm) hypothetical protein 0.0059 0.0051 0.0055
Echinococcus granulosus notch 0.0071 0.0177 0.0138
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0061 0.0067 0.0034
Brugia malayi Sex muscle abnormal protein 5 0.0089 0.0373 0.0405
Trichomonas vaginalis AGC family protein kinase 0.0182 0.1382 0.5333
Brugia malayi casein kinase I 0.0106 0.0554 0.0601
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0064 0.0108 0.0084
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.038 0.3519 0.3822
Echinococcus multilocularis notch 0.0071 0.0177 0.0168
Plasmodium falciparum cGMP-dependent protein kinase 0.0131 0.0823 0.1118
Schistosoma mansoni tyrosine kinase 0.0389 0.3617 0.4908
Loa Loa (eye worm) hypothetical protein 0.0108 0.0574 0.0624
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0106 0.0554 0.0601
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Echinococcus granulosus mitogen activated protein kinase 0.0082 0.0295 0.0257
Echinococcus multilocularis serine:threonine protein kinase N2 0.0125 0.076 0.088
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0064 0.0108 0.0231
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0064 0.0108 0.0069
Echinococcus multilocularis NCK adaptor protein 0.0091 0.0394 0.0433
Trypanosoma cruzi polo-like protein kinase, putative 0.0261 0.2232 0.3139
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0108 0.0574 0.0653
Echinococcus granulosus roundabout 2 0.0107 0.0569 0.0532
Trichomonas vaginalis CK1 family protein kinase 0.0106 0.0554 0.2016
Trypanosoma brucei casein kinase I, isoform 2 0.0106 0.0554 0.065
Brugia malayi SRC-1 0.022 0.1784 0.1937
Brugia malayi serine/threonine-protein kinase plk-2 0.0261 0.2232 0.2424
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0081 0.0288 0.032
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0084 0.0319 0.0341
Echinococcus granulosus cyclin dependent kinase 5 0.0115 0.0659 0.0623
Brugia malayi Stress-activated protein kinase jnk-1 0.0255 0.217 0.2356
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.018 0.1355 0.1605
Brugia malayi Protein kinase domain containing protein 0.0098 0.0474 0.0515
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0081 0.0288 0.0263
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0092 0.0409 0.0444
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0092 0.0412 0.0454
Echinococcus multilocularis tyrosine kinase 0.0098 0.0474 0.053
Schistosoma mansoni protein kinase 0.0084 0.0319 0.0369
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0098 0.0473 0.0529
Entamoeba histolytica cyclin C, putative 0.0205 0.1628 0.4738
Brugia malayi Immunoglobulin I-set domain containing protein 0.0092 0.0406 0.0441
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.1021 0.1336
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Trichomonas vaginalis CMGC family protein kinase 0.0082 0.0295 0.0979
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0064 0.0108 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.217 0.2917
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0089 0.0373 0.0405
Plasmodium vivax unspecified product 0.0097 0.0465 0.06
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0354 0.3234 0.3512
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0131 0.0823 0.1118
Brugia malayi Protein kinase domain containing protein 0.0433 0.409 0.4442
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0064 0.0108 0.0231
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0098 0.0473 0.0529
Entamoeba histolytica cell division protein kinase 2, putative 0.0115 0.0659 0.1797
Brugia malayi hypothetical protein 0.0061 0.0067 0.0073
Loa Loa (eye worm) hypothetical protein 0.0092 0.0406 0.0441
Brugia malayi Immunoglobulin I-set domain containing protein 0.0092 0.0406 0.0441
Brugia malayi Variant SH3 domain containing protein 0.0089 0.0373 0.0405
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0358 0.123
Echinococcus granulosus serine:threonine protein kinase 3 0.0248 0.2093 0.2062
Schistosoma mansoni protein kinase 0.0228 0.1879 0.2516
Toxoplasma gondii CMGC kinase, CK2 family 0.0097 0.0465 0.06
Entamoeba histolytica protein kinase, putative 0.0085 0.0331 0.0801
Schistosoma mansoni serine/threonine protein kinase 0.0194 0.151 0.2009
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0242 0.203 0.2863
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.011 0.0599 0.0771
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0107 0.0569 0.0532
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0242 0.203 0.2846
Schistosoma mansoni serine/threonine protein kinase 0.034 0.3087 0.4179
Brugia malayi Immunoglobulin I-set domain containing protein 0.0072 0.019 0.0206
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.2029 0.2722
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0474 0.0515
Loa Loa (eye worm) AUR protein kinase 0.0141 0.0936 0.1017
Brugia malayi Immunoglobulin I-set domain containing protein 0.0092 0.0409 0.0444
Schistosoma mansoni nck2/grb4 0.0089 0.0373 0.0444
Giardia lamblia Kinase, CMGC GSK 0.0125 0.0762 0.3076
Echinococcus granulosus glutamate synthase 0.0064 0.0108 0.0069
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0583 0.5711 0.6202
Schistosoma mansoni protein kinase 0.0106 0.0554 0.0693
Trypanosoma cruzi polo-like protein kinase, putative 0.0261 0.2232 0.3139
Onchocerca volvulus 0.0098 0.0474 0.117
Echinococcus multilocularis tyrosine protein kinase Fyn 0.022 0.1784 0.2128
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0409 0.0494
Echinococcus multilocularis mitogen activated protein kinase 14 0.0154 0.1078 0.1267
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0089 0.0373 0.0405
Echinococcus multilocularis peroxidasin 0.0092 0.041 0.0452
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0097 0.0465 0.06
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0154 0.1078 0.1465
Brugia malayi hypothetical protein 0.0187 0.1436 0.1559
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0358 0.123
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0125 0.0762 0.0827
Echinococcus granulosus neuroglian 0.0217 0.1752 0.172
Schistosoma mansoni tyrosine kinase 0.0237 0.197 0.2641
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0242 0.203 0.8181
Echinococcus multilocularis neurogenic locus protein delta 0.0071 0.0177 0.0168
Brugia malayi intracellular kinase 0.0125 0.0762 0.0827
Echinococcus granulosus tyrosine kinase 0.0098 0.0474 0.0437
Loa Loa (eye worm) hypothetical protein 0.0059 0.0055 0.006
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0574 0.068
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0659 0.0838
Loa Loa (eye worm) hypothetical protein 0.0078 0.026 0.0282
Leishmania major casein kinase II, putative 0.0097 0.0465 0.0577
Echinococcus multilocularis casein kinase I alpha 0.0106 0.0554 0.0628
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0064 0.0108 0.0059
Plasmodium falciparum casein kinase 1 0.0106 0.0554 0.0728
Echinococcus granulosus protein jagged 1 0.0071 0.0177 0.0138
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0063 0.009 0.0098
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0106 0.0554 0.0601
Schistosoma mansoni vav2 0.0101 0.0504 0.0625
Loa Loa (eye worm) hypothetical protein 0.0282 0.2457 0.2669
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0082 0.0295 0.033
Echinococcus granulosus ephrin type A receptor 4 A 0.0108 0.0575 0.0538
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.0826 0.1067
Onchocerca volvulus 0.0073 0.02 0.0404
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0061 0.0067 0.0028
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.014 0.0928 0.0893
Schistosoma mansoni cell adhesion molecule 0.0059 0.0055 0.0007
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0098 0.0473 0.0611
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0115 0.0659 0.0858
Schistosoma mansoni serine/threonine-protein kinase 0.016 0.1145 0.1506
Loa Loa (eye worm) hypothetical protein 0.0092 0.041 0.0445
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0141 0.0936 0.0901
Brugia malayi serine/threonine kinase 12 0.0141 0.0936 0.1017
Schistosoma mansoni cell adhesion molecule 0.0107 0.0569 0.0714
Schistosoma mansoni hypothetical protein 0.0071 0.0177 0.0174
Brugia malayi protein kinase C II. 0.0204 0.1617 0.1756
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0194 0.151 0.1477
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Brugia malayi casein kinase 1, delta 0.0106 0.0554 0.0601
Loa Loa (eye worm) hypothetical protein 0.0098 0.0474 0.0515
Loa Loa (eye worm) hypothetical protein 0.0172 0.1273 0.1382
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Echinococcus granulosus activin receptor type 0.0079 0.0264 0.0226
Giardia lamblia Kinase, STE STE20 0.0083 0.0304 0.0924
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0574 0.0735
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0202 0.1596 0.1563
Schistosoma mansoni tyrosine kinase 0.0107 0.0564 0.0707
Schistosoma mansoni metabotropic glutamate receptor 0.0314 0.2802 0.3786
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0539 0.5236 0.634
Loa Loa (eye worm) hypothetical protein 0.0134 0.0855 0.0929
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.2029 0.2722
Trypanosoma brucei rac serine-threonine kinase, putative 0.029 0.2547 0.3557
Entamoeba histolytica PH domain containing protein kinase, putative 0.016 0.1145 0.3271
Brugia malayi Protein kinase domain containing protein 0.0354 0.3234 0.3512
Trichomonas vaginalis AGC family protein kinase 0.029 0.2547 1
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0154 0.1078 0.1171
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0114 0.0641 0.0696
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.009 0.0098
Brugia malayi Protein kinase domain containing protein 0.0087 0.0358 0.0388
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0064 0.0108 0.0084
Schistosoma mansoni atypical protein kinase C 0.0289 0.2528 0.341
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0152 0.1052 0.1428
Onchocerca volvulus Netrin receptor homolog 0.0072 0.0193 0.0385
Loa Loa (eye worm) RGC/RGC protein kinase 0.0107 0.0564 0.0612
Entamoeba histolytica protein kinase domain containing protein 0.0079 0.0264 0.0598
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0115 0.0659 0.088
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Loa Loa (eye worm) gastrulation defective protein 1 0.026 0.2218 0.2409
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0242 0.203 0.2803
Onchocerca volvulus 0.0098 0.0474 0.117
Echinococcus granulosus NDR protein kinase 0.0163 0.1169 0.1135
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.1021 0.1336
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0187 0.1428 0.1551
Schistosoma mansoni vesicular amine transporter 0.0172 0.1273 0.1682
Plasmodium vivax casein kinase 1, putative 0.0106 0.0554 0.0728
Echinococcus granulosus tyrosine protein kinase Src42A 0.0139 0.0912 0.0876
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0465 0.1661
Trichomonas vaginalis apoptosis inducing factor, putative 0.0064 0.0108 0.0231
Onchocerca volvulus 0.0282 0.2457 0.6715
Echinococcus granulosus neural cadherin 0.0071 0.0177 0.0138
Loa Loa (eye worm) hypothetical protein 0.0282 0.2457 0.2669
Brugia malayi Immunoglobulin I-set domain containing protein 0.0281 0.2448 0.2659
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0465 0.1661
Brugia malayi hypothetical protein 0.0131 0.0822 0.0893
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0115 0.0659 0.0623
Brugia malayi hypothetical protein 0.0131 0.0822 0.0893
Echinococcus granulosus protein kinase 0.0148 0.1016 0.0981
Onchocerca volvulus Neurogenic locus notch homolog 0.0071 0.0177 0.0339
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0738 0.2754
Brugia malayi Protein kinase domain containing protein 0.0149 0.1021 0.1109
Giardia lamblia Kinase, CMGC GSK 0.0125 0.0762 0.3076
Brugia malayi Protein kinase domain containing protein 0.0293 0.2572 0.2793
Loa Loa (eye worm) hypothetical protein 0.0282 0.2457 0.2669
Leishmania major protein kinase, putative 0.0149 0.1021 0.1383
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0599 0.0755
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.011 0.0599 0.0794
Giardia lamblia Kinase, PLK 0.0261 0.2232 1
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.014 0.0923 0.1002
Trichomonas vaginalis CMGC family protein kinase 0.0149 0.1021 0.3888
Echinococcus granulosus tyrosine protein kinase Srms 0.0491 0.4708 0.4687
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0064 0.0108 0.0069
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0354 0.3234 0.3898
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0209 0.1669 0.1636
Brugia malayi Receptor family ligand binding region containing protein 0.0107 0.0564 0.0612
Schistosoma mansoni septate junction protein 0.0092 0.0406 0.049
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0182 0.1382 0.1501
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.034 0.3087 0.8475
Echinococcus multilocularis tyrosine protein kinase Fyn 0.022 0.1784 0.2128
Entamoeba histolytica protein kinase, putative 0.0081 0.0288 0.0671
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0079 0.0264 0.0285
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0077 0.0245 0.0252
Echinococcus granulosus peroxidasin 0.0092 0.041 0.0372
Schistosoma mansoni glutamate synthase 0.0064 0.0108 0.0079
Loa Loa (eye worm) hypothetical protein 0.0108 0.0574 0.0624
Toxoplasma gondii AGC kinase 0.011 0.0599 0.0794
Loa Loa (eye worm) hypothetical protein 0.0165 0.1195 0.1298
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0115 0.0659 0.0716
Echinococcus multilocularis receptor type guanylyl cyclase 0.0107 0.0564 0.064
Loa Loa (eye worm) hypothetical protein 0.0107 0.0564 0.0612
Echinococcus multilocularis death associated protein kinase 1 0.0817 0.8236 1
Echinococcus granulosus receptor type guanylyl cyclase 0.0107 0.0564 0.0527
Brugia malayi Protein kinase domain containing protein 0.0061 0.0068 0.0074
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.2232 0.8741
Echinococcus multilocularis serine:threonine protein kinase N2 0.0287 0.2516 0.3022
Schistosoma mansoni adapter molecule crk 0.0089 0.0373 0.0444
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0087 0.0354 0.0415
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0242 0.203 0.2846
Loa Loa (eye worm) TK protein kinase 0.0131 0.0824 0.0895
Trichomonas vaginalis CMGC family protein kinase 0.0125 0.0762 0.2849
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.1129 0.1485
Echinococcus granulosus N chimaerin 0.0092 0.0412 0.0374
Echinococcus multilocularis C type lectin domian containing protein 0.0131 0.0822 0.0956
Echinococcus multilocularis casein kinase i 0.0106 0.0554 0.0628
Brugia malayi Immunoglobulin I-set domain containing protein 0.0107 0.0569 0.0618
Onchocerca volvulus 0.0061 0.0067 0.0033
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0106 0.0554 0.0601
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0119 0.0695 0.091
Loa Loa (eye worm) hypothetical protein 0.0201 0.1585 0.1722
Onchocerca volvulus 0.0107 0.0564 0.1422
Brugia malayi Protein kinase domain containing protein 0.0274 0.2368 0.2571
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0242 0.203 0.2846
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.015 0.1028 0.3916
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.014 0.0928 0.1085
Echinococcus granulosus tyrosine protein kinase ABL1 0.0098 0.0474 0.0437
Leishmania major hypothetical protein, conserved 0.0064 0.0108 0.0059
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.011 0.0599 0.0651
Plasmodium falciparum ferrodoxin reductase-like protein 0.0064 0.0108 0.0084
Plasmodium falciparum apical sushi protein 0.0131 0.0822 0.1117
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0261 0.2232 0.2676
Onchocerca volvulus 0.0131 0.0822 0.2144
Brugia malayi Prion-like- 0.0092 0.0406 0.0441
Brugia malayi Sushi domain 0.0131 0.0822 0.0893
Echinococcus granulosus dual specificity 0.0135 0.0869 0.0833
Entamoeba histolytica disulphide oxidoreductase, putative 0.0064 0.0108 0.0124
Plasmodium vivax thioredoxin reductase, putative 0.07 0.6964 1
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0135 0.0869 0.1162
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Echinococcus granulosus cyclin 0.0202 0.1596 0.1563
Entamoeba histolytica PH domain containing protein kinase, putative 0.016 0.1145 0.3271
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.011 0.0599 0.0794
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0064 0.0108 0.0124
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.1169 0.154
Plasmodium falciparum protein serine/threonine kinase-1 0.0149 0.1021 0.1404
Trichomonas vaginalis CK1 family protein kinase 0.0106 0.0554 0.2016
Trichomonas vaginalis AGC family protein kinase 0.0191 0.1475 0.5705
Schistosoma mansoni tyrosine kinase 0.0343 0.312 0.4224
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0869 0.3278
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0082 0.0295 0.033
Leishmania major protein kinase A catalytic subunit isoform 1 0.011 0.0599 0.0771
Loa Loa (eye worm) hypothetical protein 0.0062 0.0079 0.0085
Schistosoma mansoni myosin-binding protein-related 0.0059 0.0055 0.0007
Onchocerca volvulus 0.0134 0.0855 0.2236
Echinococcus granulosus casein kinase I gamma 0.0206 0.164 0.1607
Trichomonas vaginalis STE family protein kinase 0.0132 0.0839 0.316
Entamoeba histolytica casein kinase, putative 0.0106 0.0554 0.1477
Echinococcus granulosus dual specificity 0.0119 0.0695 0.0658
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0149 0.1021 0.1109
Leishmania major protein kinase, putative 0.0149 0.1021 0.1383
Echinococcus multilocularis neuroglian 0.0217 0.1752 0.209
Schistosoma mansoni tyrosine kinase 0.0389 0.3617 0.4908
Echinococcus granulosus tyrosine protein kinase Fyn 0.022 0.1784 0.1751
Entamoeba histolytica protein kinase domain containing protein 0.0196 0.153 0.444
Trypanosoma cruzi hypothetical protein, conserved 0.0064 0.0108 0.0059
Schistosoma mansoni c4b-binding protein beta chain 0.0131 0.0822 0.1062
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0869 0.3278
Schistosoma mansoni serine/threonine-protein kinase 0.016 0.1145 0.1506
Loa Loa (eye worm) hypothetical protein 0.0131 0.0822 0.0893
Echinococcus granulosus dual specificity 0.0135 0.0869 0.0833
Loa Loa (eye worm) hypothetical protein 0.0172 0.1273 0.1382
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0131 0.0823 0.0957
Echinococcus multilocularis epidermal growth factor receptor 0.059 0.5779 0.7002
Brugia malayi Protein kinase domain containing protein 0.0115 0.0659 0.0716
Schistosoma mansoni bromodomain containing protein 0.0061 0.0077 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0083 0.0304 0.072
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0082 0.0295 0.033
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0419 0.3932 0.4749
Brugia malayi Doublecortin family protein 0.0146 0.0992 0.1077
Brugia malayi Protein kinase domain containing protein 0.0081 0.0288 0.0313
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0242 0.203 0.2846
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0242 0.203 0.2846
Echinococcus multilocularis protein kinase c epsilon type 0.0204 0.1617 0.1925
Onchocerca volvulus 0.0098 0.0474 0.117
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.0823 0.1063
Onchocerca volvulus 0.0282 0.2457 0.6715
Plasmodium falciparum glutathione reductase 0.07 0.6964 1
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0172 0.1273 0.1682
Trypanosoma brucei protein kinase, putative 0.0125 0.0762 0.0953
Entamoeba histolytica protein kinase domain containing protein 0.0125 0.0762 0.2108
Brugia malayi Immunoglobulin I-set domain containing protein 0.0107 0.0569 0.0618
Schistosoma mansoni hypothetical protein 0.0071 0.0177 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.164 0.2187
Echinococcus multilocularis casein kinase I delta 0.0106 0.0554 0.0628
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0149 0.1021 0.1331
Schistosoma mansoni hypothetical protein 0.0105 0.0542 0.0676
Brugia malayi Calcium binding EGF domain containing protein 0.0071 0.0177 0.0192
Schistosoma mansoni cell adhesion molecule 0.0107 0.0569 0.0714
Trypanosoma cruzi trypanothione reductase, putative 0.0242 0.203 0.2846
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0141 0.0936 0.2638
Echinococcus multilocularis fibropellin Ia 0.0071 0.0177 0.0168
Giardia lamblia Kinase, AGC AKT 0.0114 0.0641 0.2509
Brugia malayi Immunoglobulin I-set domain containing protein 0.0566 0.5526 0.6002
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0071 0.0177 0.0339
Brugia malayi Cadherin domain containing protein 0.0071 0.0177 0.0192
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0135 0.0869 0.0943
Plasmodium vivax tyrosine kinase-like protein, putative 0.0079 0.0267 0.0313
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0282 0.2454 0.2665
Schistosoma mansoni slit 0.0071 0.018 0.0178
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0083 0.0304 0.0286
Schistosoma mansoni tyrosine kinase 0.022 0.1784 0.2385
Echinococcus multilocularis rho associated protein kinase 0.0314 0.2802 0.3371
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0064 0.0108 0.0069
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0474 0.0515
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0149 0.1021 0.1383
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0141 0.0936 0.2638
Echinococcus granulosus tyrosine protein kinase Src64B 0.022 0.1784 0.1751
Schistosoma mansoni hypothetical protein 0.0071 0.0177 0.0174
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0092 0.0406 0.0981
Brugia malayi Fibronectin type III domain containing protein 0.0187 0.1436 0.1559
Echinococcus granulosus GPCR family 3 C terminal 0.0105 0.0542 0.0505
Loa Loa (eye worm) hypothetical protein 0.0264 0.2266 0.246
Loa Loa (eye worm) hypothetical protein 0.0187 0.1436 0.1559
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0242 0.203 0.2846
Trypanosoma cruzi casein kinase, putative 0.0106 0.0554 0.0705
Schistosoma mansoni roundabout 0.0092 0.0406 0.049
Echinococcus granulosus mitogen activated protein kinase 11 0.0154 0.1078 0.1043
Onchocerca volvulus 0.0137 0.0897 0.2353
Schistosoma mansoni hypothetical protein 0.0098 0.0472 0.058
Schistosoma mansoni disulfide oxidoreductase 0.0064 0.0108 0.0079
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0354 0.1215
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0059 0.0051 0.0014
Schistosoma mansoni hypothetical protein 0.0098 0.0472 0.058
Schistosoma mansoni kinase 0.0279 0.2424 0.3266
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0242 0.203 1
Entamoeba histolytica protein kinase, putative 0.0072 0.0186 0.0361
Schistosoma mansoni hypothetical protein 0.0064 0.0108 0.0079
Echinococcus multilocularis CDC7 cell division cycle 7 0.0087 0.0358 0.0389
Loa Loa (eye worm) TK/EGFR protein kinase 0.059 0.5779 0.6276
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0242 0.203 0.2803
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0474 0.0515
Echinococcus granulosus Vam6:Vps39 protein 0.0108 0.0574 0.0537
Loa Loa (eye worm) hypothetical protein 0.0098 0.0472 0.0513
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0125 0.0762 0.1007
Trichomonas vaginalis CMGC family protein kinase 0.0082 0.0295 0.0979
Onchocerca volvulus Putative cubilin 0.0071 0.0177 0.0339
Trichomonas vaginalis STE family protein kinase 0.0084 0.0319 0.1074
Echinococcus granulosus protein kinase c iota type 0.0283 0.2465 0.2435
Brugia malayi serine/threonine-protein kinase 6 0.0141 0.0936 0.1017
Entamoeba histolytica hypothetical protein 0.0119 0.0695 0.1905
Toxoplasma gondii rhoptry neck protein RON1 0.0131 0.0822 0.1117
Echinococcus multilocularis glutamate receptor 2 0.0061 0.0067 0.0034
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0242 0.203 0.2863
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Echinococcus granulosus protein jagged 2 0.0071 0.0177 0.0138
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0178 0.1336 0.145
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0073 0.0089
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0242 0.203 0.8181
Giardia lamblia Kinase, CMGC CDK 0.0115 0.0659 0.2594
Brugia malayi Hr1 repeat family protein 0.0287 0.2516 0.2732
Loa Loa (eye worm) notch protein 0.0071 0.0177 0.0192
Echinococcus multilocularis casein kinase I gamma 0.0206 0.164 0.1953
Brugia malayi pregnancy-associated plasma protein-A 0.0131 0.0822 0.0893
Brugia malayi Protein kinase domain containing protein 0.0907 0.9208 1
Echinococcus granulosus slit 2 protein 0.0098 0.0474 0.0437
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0064 0.0108 0.0084
Leishmania major protein kinase, putative 0.0098 0.0473 0.0588
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0242 0.203 0.2803
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0082 0.0295 0.0272
Entamoeba histolytica protein kinase, putative 0.0119 0.0695 0.1905
Entamoeba histolytica casein kinase 1, putative 0.0106 0.0554 0.1477
Loa Loa (eye worm) hypothetical protein 0.0105 0.0542 0.0589
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Onchocerca volvulus 0.0131 0.0822 0.2144
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0119 0.0698 0.0804
Trichomonas vaginalis AGC family protein kinase 0.029 0.2547 1
Echinococcus multilocularis cyclin dependent kinase 19 0.0293 0.2572 0.309
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0242 0.203 0.2863
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0172 0.1273 0.1505
Echinococcus multilocularis nervana 2 0.0119 0.0698 0.0804
Entamoeba histolytica casein kinase, putative 0.0097 0.0465 0.1207
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0242 0.203 0.2803
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0465 0.1661
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0107 0.0569 0.0618
Loa Loa (eye worm) TK protein kinase 0.0338 0.3061 0.3325
Brugia malayi glutathione reductase 0.07 0.6964 0.7562
Loa Loa (eye worm) hypothetical protein 0.0578 0.5657 0.6143
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0149 0.1021 0.1331
Onchocerca volvulus 0.0282 0.2457 0.6715
Loa Loa (eye worm) hypothetical protein 0.0344 0.3128 0.3397
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0242 0.203 0.2803
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0064 0.0108 0.0231
Onchocerca volvulus Slit protein homolog 0.0098 0.0474 0.117
Trypanosoma brucei cdc2-related kinase 1 0.0115 0.0659 0.0804
Loa Loa (eye worm) hypothetical protein 0.0092 0.0406 0.0441
Schistosoma mansoni notch 0.0071 0.0177 0.0174
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0242 0.203 0.2429
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0106 0.0554 0.0705
Brugia malayi Protein kinase domain containing protein 0.034 0.3087 0.3352
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0119 0.0695 0.091
Echinococcus granulosus protein tyrosine kinase 0.0533 0.5167 0.5148
Brugia malayi SH2 domain containing protein 0.039 0.3625 0.3937
Entamoeba histolytica serine/threonine protein kinase, putative 0.0087 0.0354 0.087
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0419 0.3932 0.3908
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0869 0.3278
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0079 0.0271 0.0295
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0108 0.0574 0.0721
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.018 0.1355 0.1471
Brugia malayi Cam kinase protein 1 0.0098 0.0473 0.0513
Loa Loa (eye worm) hypothetical protein 0.022 0.1787 0.194
Loa Loa (eye worm) cyclin C 0.0407 0.381 0.4138
Echinococcus multilocularis serine threonine protein kinase 0.0202 0.1594 0.1897
Loa Loa (eye worm) hypothetical protein 0.0071 0.0177 0.0192
Schistosoma mansoni protein kinase 0.0228 0.1879 0.2516
Onchocerca volvulus 0.0098 0.0474 0.117
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.011 0.0599 0.0771
Echinococcus granulosus fibroblast growth factor receptor 4 0.0237 0.197 0.1938
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0135 0.0869 0.1162
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0196 0.153 0.1661

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.18 uM Tested for the inhibition of human plasma renin ChEMBL. 3295239

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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