Detailed information for compound 368283

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 501.077 | Formula: C29H39ClNO4-
  • H donors: 2 H acceptors: 2 LogP: 4.84 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: CO[C@@]12CC[C@]3(C[C@@H]1[C@](C1CC1)(O)C)[C@]14[C@H]2Oc2c4c(CC3N(CC1)CC1CCC1)ccc2O.[Cl-]
  • InChi: 1S/C29H39NO4.ClH/c1-26(32,19-7-8-19)21-15-27-10-11-29(21,33-2)25-28(27)12-13-30(16-17-4-3-5-17)22(27)14-18-6-9-20(31)24(34-25)23(18)28;/h6,9,17,19,21-22,25,31-32H,3-5,7-8,10-16H2,1-2H3;1H/p-1/t21-,22?,25-,26+,27-,28+,29-;/m1./s1
  • InChiKey: VKSAMFRKCVBQBZ-GVBWWAFJSA-M  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) CXXC zinc finger family protein 0.0214 0.0258 0.038
Toxoplasma gondii hypothetical protein 0.0187 0.0221 0.4034
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0075 0.0068 0.0067
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Onchocerca volvulus 0.0217 0.0262 0.0963
Echinococcus multilocularis voltage dependent calcium channel 0.0187 0.0221 0.022
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Trypanosoma cruzi Thiopurine S-methyltransferase (TPMT), putative 0.0048 0.0031 0.0559
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Entamoeba histolytica hypothetical protein 0.0149 0.017 0.1939
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0217 0.0262 0.0386
Brugia malayi nuclear receptor NHR-88 0.0033 0.001 0.0013
Brugia malayi Guanylyl cyclase protein 23 0.0149 0.017 0.0249
Onchocerca volvulus 0.0043 0.0024 0.008
Echinococcus multilocularis tumor protein p63 0.1482 0.1995 0.1995
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.01 0.0102 0.1168
Echinococcus granulosus lamin 0.0172 0.0201 0.02
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0033 0.001 0.0028
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0029 0.0004 0.0099
Echinococcus multilocularis ferritin 0.0107 0.0112 0.0111
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0054 0.0039 0.0143
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0001 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.003 0.0111
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0123 0.0133 0.0196
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Giardia lamblia Kinase, CMGC MAPK 0.0106 0.011 0.125
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0033 0.001 0.0007
Echinococcus multilocularis NMDA receptor 0.0291 0.0364 0.0363
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0054 0.0039 0.0136
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0187 0.0221 0.0325
Toxoplasma gondii LsmAD domain-containing protein 0.01 0.0103 0.1861
Mycobacterium leprae Probable lipase LipE 0.0292 0.0365 0.8829
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus expressed protein 0.0107 0.0112 0.0111
Echinococcus multilocularis two pore calcium channel protein 1 0.0187 0.0221 0.022
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0054 0.0039 0.0143
Brugia malayi cytoplasmic intermediate filament protein 0.0092 0.0091 0.0134
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0045 0.0027 0.0026
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0415 0.0534 0.0533
Loa Loa (eye worm) hypothetical protein 0.0058 0.0044 0.0064
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Trypanosoma cruzi trypanothione reductase, putative 0.0083 0.0079 0.1425
Entamoeba histolytica heat shock transcription factor, putative 0.0114 0.0121 0.1377
Echinococcus granulosus transient receptor potential cation channel 0.0187 0.0221 0.022
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0001 0.0011
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0291 0.0364 0.0363
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0248 0.0305 0.0449
Schistosoma mansoni hypothetical protein 0.0886 0.1179 0.1177
Brugia malayi jmjC domain containing protein 0.0103 0.0106 0.0155
Schistosoma mansoni cytochrome P450 0.0054 0.0039 0.0036
Leishmania major hypothetical protein, conserved 0.0217 0.0262 0.7171
Brugia malayi olfactory channel protein osm-9 0.0187 0.0221 0.0325
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0054 0.0039 0.0691
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0002 0.0001
Plasmodium vivax kelch protein K13, putative 0.0217 0.0262 0.7168
Schistosoma mansoni transient receptor potential channel 0.0187 0.0221 0.0219
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0029 0.0004 0.0088
Loa Loa (eye worm) hypothetical protein 0.003 0.0006 0.0007
Echinococcus multilocularis beta LACTamase domain containing family member 0.0292 0.0365 0.0363
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0107 0.0112 0.0429
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0029 0.0004 0.0099
Giardia lamblia GTOR 0.0047 0.003 0.033
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0031 0.0115
Loa Loa (eye worm) hypothetical protein 0.0322 0.0407 0.06
Echinococcus granulosus 5'partial|Low density lipoprotein receptor class A cysteine rich 0.0029 0.0005 0.0004
Schistosoma mansoni cellular tumor antigen P53 0.0217 0.0262 0.026
Trypanosoma brucei transcription factor BTF3, putative 0.0039 0.0018 0.0477
Echinococcus granulosus mitogen activated protein kinase 3 0.0106 0.011 0.0109
Brugia malayi Dopamine receptor 0.0027 0.0002 0.0002
Trypanosoma cruzi cytochrome P450, putative 0.0082 0.0078 0.1413
Loa Loa (eye worm) voltage-gated potassium channel 0.0187 0.0221 0.0325
Trichomonas vaginalis glutaminase, putative 0.0306 0.0384 0.1427
Schistosoma mansoni lipoxygenase 0.039 0.0499 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0008 0.0031
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0192 0.0229 0.0337
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0187 0.0221 0.022
Echinococcus multilocularis calcium activated potassium channel 0.0189 0.0224 0.0222
Schistosoma mansoni ferritin 0.0107 0.0112 0.011
Schistosoma mansoni myelin transcription factor 1 myt1 0.0119 0.0128 0.0125
Mycobacterium tuberculosis Probable methyltransferase 0.0184 0.0217 0.0846
Schistosoma mansoni thyroid hormone receptor 0.0033 0.001 0.0007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0003 0.0012
Loa Loa (eye worm) O-methyltransferase 0.0184 0.0217 0.0319
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0187 0.0221 0.022
Brugia malayi Dopamine receptor protein 2 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Probable oxidoreductase 0.021 0.0253 0.099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) carboxylesterase 0.0054 0.004 0.0057
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0149 0.017 0.0249
Echinococcus granulosus RUN 0.0089 0.0087 0.0086
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0106 0.011 0.3002
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0027 0.0002 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Onchocerca volvulus 0.0029 0.0005 0.0011
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.474 0.646 0.646
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0248 0.0305 0.0449
Echinococcus multilocularis neuropeptide receptor A26 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0292 0.0365 0.0538
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.0049 0.0183
Echinococcus multilocularis glutamate receptor NMDA 0.195 0.2636 0.2635
Echinococcus granulosus BTB:POZ domain containing protein KCTD16 0.0217 0.0262 0.0261
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0017 0.005
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0008 0.0125
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0054 0.0039 0.0136
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0187 0.0221 0.0219
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0054 0.0039 0.0143
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0054 0.004 0.014
Echinococcus multilocularis receptor type guanylyl cyclase 0.0149 0.017 0.0168
Brugia malayi putative neuropeptide receptor NPR1 0.0027 0.0002 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0088 0.0086
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0038
Schistosoma mansoni importin beta-1 0.0032 0.0009 0.0007
Onchocerca volvulus 0.0029 0.0005 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Brugia malayi Pre-SET motif family protein 0.1751 0.2364 0.3497
Echinococcus multilocularis glutamate receptor 2 0.0441 0.0569 0.0568
Onchocerca volvulus 0.0929 0.1238 0.4591
Mycobacterium tuberculosis Carboxylesterase LipT 0.0054 0.004 0.014
Wolbachia endosymbiont of Brugia malayi O-methyltransferase 0.0184 0.0217 1
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.003 0.079
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0212 0.0255 0.6988
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0027 0.0002 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.01 0.0103 0.3892
Schistosoma mansoni patched 1 0.0045 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Brugia malayi hypothetical protein 0.0149 0.017 0.0249
Echinococcus multilocularis potassium large conductance calcium activated 0.0187 0.0221 0.022
Schistosoma mansoni bromodomain containing protein 0.003 0.0006 0.0003
Onchocerca volvulus Protein ultraspiracle homolog 0.0033 0.001 0.0028
Echinococcus granulosus Low density lipoprotein receptor class A cysteine rich 0.0029 0.0005 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0234 0.0285 0.0283
Echinococcus multilocularis thyroid hormone receptor alpha 0.0033 0.001 0.0009
Leishmania major hypothetical protein, conserved 0.0217 0.0262 0.7171
Trichomonas vaginalis chromobox protein, putative 0.008 0.0075 0.0277
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0187 0.0221 0.0219
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Entamoeba histolytica hypothetical protein 0.0114 0.0122 0.1388
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.001 0.0013
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0002 0.0001
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0415 0.0534 0.0533
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0212 0.0255 0.0376
Echinococcus multilocularis mitogen activated protein kinase 0.0106 0.011 0.0109
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0002 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.001 0.0013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0248 0.0305 0.0302
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0002 0.0001
Brugia malayi isocitrate dehydrogenase 0.0032 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Echinococcus granulosus peptide allatostatin:somatostatin 0.0027 0.0002 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Echinococcus granulosus sex peptide receptor 0.0027 0.0002 0.0001
Giardia lamblia NADH oxidase lateral transfer candidate 0.0029 0.0004 0.0037
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0001 0.0004
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0009 0.021
Brugia malayi AMP-binding enzyme family protein 0.0054 0.0038 0.0055
Brugia malayi Low-density lipoprotein receptor-related protein, putative 0.0029 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0149 0.017 0.0249
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0002 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Mycobacterium ulcerans hypothetical protein 0.0054 0.0038 0.0143
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Echinococcus granulosus voltage gated hydrogen channel 1 0.0187 0.0221 0.022
Leishmania major hypothetical protein, conserved 0.0048 0.0031 0.084
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0008 0.001
Brugia malayi Voltage-gated potassium channel, Shal-family (KCND, Kv4-like) alpha-subunit. C. elegans shl-1 ortholog 0.0217 0.0262 0.0386
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Schistosoma mansoni inositol transporter 0.0043 0.0024 0.0021
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0027 0.0002 0.0001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0202 0.0242 0.0356
Plasmodium vivax importin-beta 2, putative 0.0032 0.0009 0.0219
Loa Loa (eye worm) hypothetical protein 0.0184 0.0217 0.0319
Echinococcus granulosus lamin dm0 0.0172 0.0201 0.02
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0212 0.0255 0.4652
Echinococcus granulosus dna polymerase eta 0.0045 0.0027 0.0026
Schistosoma mansoni lipoxygenase 0.0229 0.0279 0.0277
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0044 0.0042
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0002 0.0001
Schistosoma mansoni o-methyltransferase 0.0184 0.0217 0.0215
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0187 0.0221 0.0325
Trypanosoma brucei PAB1-binding protein , putative 0.01 0.0103 0.279
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0033 0.001 0.0009
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Schistosoma mansoni glutamate receptor kainate 0.0291 0.0364 0.0362
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0033 0.001 0.0009
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0029 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0217 0.0262 0.0386
Schistosoma mansoni o-methyltransferase 0.0184 0.0217 0.0215
Onchocerca volvulus 0.0268 0.0332 0.1226
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0054 0.0039 0.0143
Echinococcus multilocularis transient receptor potential cation channel 0.0187 0.0221 0.022
Onchocerca volvulus 0.0033 0.001 0.0028
Schistosoma mansoni hypothetical protein 0.0044 0.0025 0.0023
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0114 0.0122 0.012
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0054 0.0039 0.0143
Brugia malayi HSF-type DNA-binding domain containing protein 0.0114 0.0121 0.0177
Loa Loa (eye worm) hypothetical protein 0.0054 0.0038 0.0055
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0106 0.011 0.1997
Schistosoma mansoni transcription factor LCR-F1 0.0114 0.0122 0.0119
Toxoplasma gondii K+ channel tetramerisation domain-containing protein 0.0217 0.0262 0.4781
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Echinococcus multilocularis musashi 0.0172 0.0201 0.02
Onchocerca volvulus 0.0149 0.017 0.0621
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.004 0.002 0.0062
Schistosoma mansoni smad 0.0034 0.0012 0.0009
Schistosoma mansoni transcription factor btf3 0.0039 0.0018 0.0016
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0292 0.0365 0.1433
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0092 0.0091 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0029 0.0004 0.0003
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0323 0.0408 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0029 0.0004 0.0123
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0062 0.005 0.0049
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0027 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Trichomonas vaginalis mercuric reductase, putative 0.0029 0.0004 0.0016
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0217 0.0262 0.4772
Loa Loa (eye worm) hypothetical protein 0.0217 0.0262 0.0386
Echinococcus multilocularis peregrin 0.0041 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0106 0.011 0.3002
Brugia malayi Cytochrome P450 family protein 0.0178 0.0209 0.0307
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0187 0.0221 0.022
Echinococcus multilocularis Niemann Pick C1 protein 0.0106 0.011 0.0109
Schistosoma mansoni survival motor neuron protein 0.0315 0.0397 0.0395
Schistosoma mansoni ferritin 0.0107 0.0112 0.011
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0217 0.0262 0.0386
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0292 0.0365 0.1433
Loa Loa (eye worm) carboxylesterase 0.0322 0.0407 0.06
Brugia malayi Receptor family ligand binding region containing protein 0.0149 0.017 0.0249
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.004 0.002 0.0028
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.039 0.0499 0.0498
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0189 0.0224 0.0875
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Toxoplasma gondii NAC domain-containing protein 0.0039 0.0018 0.0318
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0017 0.005
Leishmania major extracellular receptor, putative 0.0149 0.017 0.4641
Leishmania major potassium voltage-gated channel, putative 0.0217 0.0262 0.7171
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.009 0.0088 0.0129
Schistosoma mansoni vesicular amine transporter 0.0403 0.0518 0.0515
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Mycobacterium tuberculosis Conserved protein 0.0292 0.0365 0.1433
Echinococcus granulosus potassium voltage gated channel protein 0.4957 0.6757 0.6756
Echinococcus multilocularis sex peptide receptor 0.0027 0.0002 0.0001
Echinococcus multilocularis potassium voltage gated channel protein 0.0403 0.0518 0.0517
Echinococcus multilocularis G-protein coupled receptor, putative 0.0027 0.0002 0.0001
Echinococcus multilocularis zinc finger protein 0.0092 0.0091 0.009
Loa Loa (eye worm) potassium channel tetramerisation domain containing 5 0.0217 0.0262 0.0386
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0353 0.0448 0.5138
Brugia malayi Niemann-Pick C1 protein precursor 0.0106 0.011 0.0161
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0033 0.001 0.0009
Schistosoma mansoni voltage-gated potassium channel 0.4957 0.6757 0.6756
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0187 0.0221 0.6049
Schistosoma mansoni edp1-related 0.0217 0.0262 0.0259
Loa Loa (eye worm) RGC/RGC protein kinase 0.0149 0.017 0.0249
Echinococcus multilocularis Niemann Pick C1 protein 0.0151 0.0172 0.0171
Trypanosoma cruzi cdc2-related kinase 1 0.009 0.0088 0.1598
Trichomonas vaginalis glutathione reductase, putative 0.0029 0.0004 0.0016
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0008 0.0006
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0054 0.0039 0.0691
Trypanosoma cruzi extracellular receptor, putative 0.0149 0.017 0.3088
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0054 0.004 0.0038
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0291 0.0364 0.0363
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0202 0.0242 0.0241
Brugia malayi Glutamate receptor 2 precursor 0.0291 0.0364 0.0537
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0083 0.0079 0.0078
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0061 0.0048 0.0862
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0018 0.0324
Schistosoma mansoni lozenge 0.0117 0.0125 0.0122
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0202 0.0242 0.0241
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0747 0.0988 0.3914
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0187 0.0221 0.0325
Schistosoma mansoni glutamate receptor AMPA 0.0291 0.0364 0.0362
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0107 0.0112 0.5072
Echinococcus granulosus lipoxygenase domain containing protein 0.0089 0.0087 0.0086
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.003 0.079
Echinococcus granulosus mixed lineage leukemia protein mll 0.0062 0.005 0.0049
Toxoplasma gondii histone lysine methyltransferase SET1 0.0424 0.0546 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.0027 0.0038
Trichomonas vaginalis D-aminoacylase, putative 0.0292 0.0365 0.1353
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0187 0.0221 0.0219
Trypanosoma cruzi hypothetical protein 0.0425 0.0547 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0241 0.0295 0.0294
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0054 0.0039 0.0136
Brugia malayi mbt repeat family protein 0.0104 0.0108 0.0158
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0043 0.0024 0.0023
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0315 0.0397 0.0586
Onchocerca volvulus 0.1992 0.2694 1
Brugia malayi RE15519p 0.0027 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Plasmodium falciparum kelch protein K13 0.0217 0.0262 1
Schistosoma mansoni rab6-interacting 0.0089 0.0087 0.0085
Mycobacterium tuberculosis Conserved protein 0.0048 0.0031 0.0107
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0248 0.0305 0.0302
Echinococcus multilocularis neuroligin 0.0054 0.004 0.0038
Mycobacterium ulcerans carboxylesterase, LipT 0.0054 0.004 0.0148
Onchocerca volvulus Terribly reduced optic lobes homolog 0.0029 0.0005 0.0011
Echinococcus granulosus fetal alzheimer antigen falz 0.0104 0.0108 0.0107
Echinococcus granulosus neuropeptide receptor A26 0.0027 0.0002 0.0001
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0062 0.005 0.0049
Onchocerca volvulus 0.0217 0.0262 0.0963
Echinococcus multilocularis ryanodine receptor 44f 0.0187 0.0221 0.022
Schistosoma mansoni inositol transporter 0.0043 0.0024 0.0021
Loa Loa (eye worm) glutamate receptor 2 0.0291 0.0364 0.0537
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0029 0.0005 0.0003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0004 0.0066
Entamoeba histolytica hypothetical protein 0.0114 0.0122 0.1388
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0119 0.0128 0.0187
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0002 0.0001
Echinococcus granulosus transient receptor potential cation channel 0.0187 0.0221 0.022
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0029 0.0005 0.0004
Schistosoma mansoni mixed-lineage leukemia protein mll 0.004 0.002 0.0017
Brugia malayi sulfakinin receptor protein 0.0027 0.0002 0.0002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0009 0.0008
Onchocerca volvulus 0.0217 0.0262 0.0963
Echinococcus multilocularis BC026374 protein (S09 family) 0.0054 0.004 0.0038
Echinococcus multilocularis thioredoxin glutathione reductase 0.0084 0.008 0.0079
Brugia malayi follicle stimulating hormone receptor 0.0027 0.0002 0.0002
Leishmania major DNA polymerase eta, putative 0.0045 0.0027 0.0726
Echinococcus granulosus 7TM GPCR rhodopsin 0.0027 0.0002 0.0001
Leishmania major cytochrome p450-like protein 0.0082 0.0078 0.2123
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0002 0.0001
Echinococcus multilocularis high affinity choline transporter 1 0.0389 0.0498 0.0497
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0149 0.017 0.0621
Brugia malayi AKH receptor 0.0027 0.0002 0.0002
Echinococcus granulosus potassium voltage gated channel protein 0.0187 0.0221 0.022
Echinococcus multilocularis acetylcholinesterase 0.0322 0.0407 0.0406
Schistosoma mansoni voltage-gated ion channel 0.0187 0.0221 0.0219
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0137 0.0153 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Schistosoma mansoni glutamate receptor AMPA 0.0291 0.0364 0.0362
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Echinococcus multilocularis microtubule associated protein 2 0.7324 1 1
Trypanosoma brucei btb/poz domain containing protein, putative 0.0217 0.0262 0.7168
Echinococcus multilocularis lamin dm0 0.0172 0.0201 0.02
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0054 0.004 0.0147
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0009 0.021
Giardia lamblia Kinase, CMGC CDK 0.009 0.0088 0.0999
Schistosoma mansoni DNA polymerase eta 0.0045 0.0027 0.0025
Echinococcus multilocularis 0.0054 0.0039 0.0037
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0187 0.0221 0.022
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0008 0.0007
Onchocerca volvulus 0.0217 0.0262 0.0963
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0027 0.0002 0.0002
Trypanosoma brucei ISWI complex protein 0.0063 0.0051 0.1365
Plasmodium vivax multidomain scavenger receptor, putative 0.0089 0.0087 0.2372
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0137 0.0153 0.059
Giardia lamblia PHD finger protein 15 0.0031 0.0008 0.0078
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0403 0.0518 0.0517
Leishmania major 4-coumarate:coa ligase-like protein 0.0054 0.0038 0.1037
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Giardia lamblia Kinase, CMGC CDK 0.009 0.0088 0.0999
Echinococcus multilocularis nmda type glutamate receptor 0.2099 0.2841 0.284
Onchocerca volvulus Huntingtin homolog 0.0123 0.0133 0.0487
Schistosoma mansoni o-methyltransferase 0.0184 0.0217 0.0215
Mycobacterium ulcerans bacterioferritin BfrB 0.0107 0.0112 0.0451
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Schistosoma mansoni metabotropic glutamate receptor 0.0149 0.017 0.0167
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0437 0.0563 0.0832
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.009 0.0088 0.2402
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Conserved protein 0.0292 0.0365 0.1433
Loa Loa (eye worm) hypothetical protein 0.0951 0.1267 0.1874
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0033 0.001 0.0009
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0054 0.0039 0.0143
Brugia malayi enteropeptidase precursor 0.0029 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Echinococcus multilocularis sodium leak channel non selective protein 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0292 0.0365 0.0538
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0054 0.0039 0.0136
Echinococcus granulosus cyclin dependent kinase 1 0.009 0.0088 0.0087
Echinococcus granulosus shaker cognate 0.0403 0.0518 0.0517
Echinococcus granulosus hyperpolarization activated cyclic 0.0187 0.0221 0.022
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0187 0.0221 0.0219
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0054 0.0039 0.0143
Loa Loa (eye worm) voltage-dependent calcium channel 0.0187 0.0221 0.0325
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Echinococcus multilocularis allatostatin A receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0172 0.0201 0.0296
Mycobacterium ulcerans aldehyde dehydrogenase 0.0137 0.0153 0.0621
Brugia malayi Carboxylesterase family protein 0.0054 0.004 0.0057
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0054 0.0039 0.1039
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0054 0.004 0.0038
Schistosoma mansoni hypothetical protein 0.0202 0.0242 0.024
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0008 0.0125
Echinococcus granulosus smad 0.0034 0.0012 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0255 0.0314 0.0312
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0033 0.001 0.0013
Brugia malayi O-methyltransferase family protein 0.0184 0.0217 0.0319
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0033 0.001 0.0013
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Toxoplasma gondii aldehyde dehydrogenase 0.0137 0.0153 0.2782
Mycobacterium ulcerans esterase/lipase LipP 0.0292 0.0365 0.1508
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.003 0.0029
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0027 0.0002 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.001 0.0013
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0075 0.0068 0.0067
Brugia malayi mbt repeat family protein 0.0104 0.0108 0.0158
Entamoeba histolytica hypothetical protein 0.0039 0.0018 0.0204
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0054 0.0038 0.0143
Echinococcus granulosus glutamate receptor 2 0.0149 0.017 0.0168
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Echinococcus granulosus basement membrane specific heparan sulfate 0.0029 0.0005 0.0004
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.4957 0.6757 1
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.011 0.0408
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.021 0.0253 0.5817
Echinococcus granulosus transcription factor btf3 0.0039 0.0018 0.0017
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0017 0.029
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0009 0.0008
Echinococcus granulosus aryl hydrocarbon receptor 0.0028 0.0004 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0062
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0106 0.011 0.1253
Echinococcus granulosus G protein coupled receptor 139 0.0027 0.0002 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0217 0.0262 0.0259
Loa Loa (eye worm) ryanodine receptor 0.0187 0.0221 0.0325
Echinococcus granulosus sodium:glucose cotransporter 2 0.0043 0.0024 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0054 0.0039 0.0136
Schistosoma mansoni myst-related protein 0.0033 0.001 0.0008
Mycobacterium tuberculosis Probable reductase 0.0189 0.0224 0.0875
Onchocerca volvulus 0.0089 0.0087 0.0316
Schistosoma mansoni tyrosine kinase 0.0149 0.017 0.0167
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0054 0.0038 0.0143
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0033 0.001 0.0009
Echinococcus granulosus chromobox protein 1 0.008 0.0075 0.0073
Loa Loa (eye worm) hypothetical protein 0.008 0.0075 0.0109
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0009 0.0219
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0029 0.0005 0.0004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0019 0.0069
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0066
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Mycobacterium ulcerans aldehyde dehydrogenase 0.0137 0.0153 0.0621
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0217 0.0262 0.4772
Loa Loa (eye worm) hypothetical protein 0.0054 0.0038 0.0055
Brugia malayi F/Y-rich N-terminus family protein 0.0093 0.0092 0.0134
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0248 0.0305 0.0304
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus voltage dependent calcium channel 0.0187 0.0221 0.022
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0002 0.0001
Echinococcus granulosus basement membrane specific heparan sulfate 0.0029 0.0005 0.0004
Trypanosoma cruzi potassium voltage-gated channel, putative 0.0217 0.0262 0.4772
Brugia malayi hypothetical protein 0.0089 0.0087 0.0128
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0187 0.0221 0.022
Echinococcus granulosus Niemann Pick C1 protein 0.0106 0.011 0.0109
Schistosoma mansoni hypothetical protein 0.0187 0.0221 0.0219
Schistosoma mansoni transient receptor potential channel 0.0187 0.0221 0.0219
Echinococcus granulosus transient receptor potential gamma protein 0.0187 0.0221 0.022
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis short transient receptor potential channel 6 0.0187 0.0221 0.022
Echinococcus granulosus cyclin dependent kinase 0.009 0.0088 0.0087
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0518 0.0515
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.011 0.0408
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0054 0.0039 0.0136
Echinococcus granulosus peregrin 0.0041 0.0021 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.0049 0.0183
Onchocerca volvulus 0.0214 0.0258 0.095
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0017 0.005
Brugia malayi AMP-binding enzyme family protein 0.0054 0.0038 0.0055
Echinococcus multilocularis cpg binding protein 0.0234 0.0285 0.0284
Brugia malayi GnHR receptor homolog 0.0027 0.0002 0.0002
Toxoplasma gondii NADPH-glutathione reductase 0.0029 0.0004 0.0059
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0027 0.0483
Echinococcus granulosus potassium voltage gated channel protein 0.0187 0.0221 0.022
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0292 0.0365 0.1433
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.011 0.0408
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0054 0.0078
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0344 0.0436 0.0434
Echinococcus multilocularis protein dispatched 1 0.0052 0.0036 0.0035
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0054 0.0039 0.0143
Echinococcus multilocularis aryl hydrocarbon receptor 0.0028 0.0004 0.0003
Brugia malayi Bromodomain containing protein 0.0041 0.0021 0.003
Loa Loa (eye worm) hypothetical protein 0.0054 0.0039 0.0056
Schistosoma mansoni acetylcholinesterase 0.0054 0.004 0.0037
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.001 0.0013
Schistosoma mansoni o-methyltransferase 0.0184 0.0217 0.0215
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0747 0.0988 1
Brugia malayi putative neuropeptide receptor 0.0027 0.0002 0.0002
Schistosoma mansoni BC026374 protein (S09 family) 0.0054 0.004 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0004 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0033 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0043 0.0024 0.0033
Mycobacterium ulcerans O-methyltransferase 0.1772 0.2393 1
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.003 0.0334
Echinococcus granulosus snurportin 1 0.0344 0.0436 0.0435
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0212 0.0255 0.0254
Schistosoma mansoni bromodomain containing protein 0.0271 0.0337 0.0334
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0012 0.0011
Schistosoma mansoni transient receptor potential channel 0.0187 0.0221 0.0219
Brugia malayi Latrophilin receptor protein 2 0.0202 0.0242 0.0356
Schistosoma mansoni polycystin 1-related 0.0089 0.0087 0.0085
Entamoeba histolytica heat shock transcription factor, putative 0.0114 0.0121 0.1377
Echinococcus multilocularis histone acetyltransferase MYST2 0.0119 0.0128 0.0127
Loa Loa (eye worm) hypothetical protein 0.004 0.002 0.0028
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.003 0.08
Schistosoma mansoni voltage-gated potassium channel 0.4957 0.6757 0.6756
Echinococcus multilocularis two pore calcium channel protein 2 0.0187 0.0221 0.022
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Toxoplasma gondii transporter, cation channel family protein 0.0187 0.0221 0.4034
Echinococcus multilocularis somatostatin receptor 0.0027 0.0002 0.0001
Brugia malayi ecdysteroid receptor 0.0033 0.001 0.0013
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0002 0.0001
Trichomonas vaginalis set domain proteins, putative 0.1992 0.2694 1
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0149 0.017 0.0168
Loa Loa (eye worm) hypothetical protein 0.0951 0.1267 0.1874
Loa Loa (eye worm) hypothetical protein 0.0029 0.0004 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0248 0.0305 0.0302
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0518 0.0515
Loa Loa (eye worm) glutaminase 2 0.0306 0.0384 0.0567
Brugia malayi G-protein coupled receptor 0.0027 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0044 0.0025 0.0023
Echinococcus granulosus neuropeptide receptor 0.0027 0.0002 0.0001
Onchocerca volvulus Alhambra homolog 0.0031 0.0008 0.0021
Loa Loa (eye worm) hypothetical protein 0.004 0.002 0.0028
Plasmodium vivax thioredoxin reductase, putative 0.0083 0.0079 0.2133
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.003 0.0028
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0027 0.0002 0.0002
Echinococcus granulosus beta LACTamase domain containing family member 0.0292 0.0365 0.0363
Loa Loa (eye worm) hypothetical protein 0.0123 0.0133 0.0196
Echinococcus multilocularis transcription factor btf3 0.0039 0.0018 0.0017
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0471 0.061 0.0902
Echinococcus multilocularis chromobox protein 1 0.008 0.0075 0.0073
Entamoeba histolytica hypothetical protein 0.01 0.0102 0.1168
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Schistosoma mansoni protein kinase 0.0149 0.017 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0004 0.0014
Brugia malayi K+ channel tetramerisation domain containing protein 0.0217 0.0262 0.0386
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0104 0.0108 0.0106
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0012 0.0011
Echinococcus multilocularis protein patched 0.0045 0.0027 0.0026
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0187 0.0221 0.0219
Onchocerca volvulus 0.0054 0.004 0.0139
Echinococcus granulosus acetylcholinesterase 0.0322 0.0407 0.0406
Loa Loa (eye worm) glutaminase 0.0306 0.0384 0.0567
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Schistosoma mansoni loxhd1 0.0089 0.0087 0.0085
Schistosoma mansoni voltage-gated potassium channel 0.0217 0.0262 0.0259
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0009 0.014
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0002 0.0001
Plasmodium vivax K+ channel tetramerisation domain containing protein 0.0217 0.0262 0.7168
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.0004 0.0066
Loa Loa (eye worm) RNA binding protein 0.0471 0.061 0.0902
Mycobacterium ulcerans aldehyde dehydrogenase 0.0137 0.0153 0.0621
Echinococcus multilocularis orexin receptor type 2 0.0027 0.0002 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0088 0.0327
Leishmania major 4-coumarate:coa ligase-like protein 0.0054 0.0038 0.1037
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0002 0.0002
Mycobacterium ulcerans methyltransferase 0.0048 0.0031 0.0113
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Toxoplasma gondii ABC1 family protein 0.0292 0.0365 0.6669
Brugia malayi glutathione reductase 0.0083 0.0079 0.0115
Echinococcus granulosus voltage gated potassium channel 0.0403 0.0518 0.0517
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0018 0.0069
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0187 0.0221 0.4028
Entamoeba histolytica heat shock transcription factor, putative 0.0114 0.0121 0.1377
Loa Loa (eye worm) cytochrome P450 family protein 0.0082 0.0078 0.0114
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) bromodomain containing protein 0.0072 0.0064 0.0093
Echinococcus granulosus g protein coupled receptor 0.0027 0.0002 0.0001
Echinococcus granulosus neuropeptide FF receptor 2 0.0027 0.0002 0.0001
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0002 0.0001
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0403 0.0518 0.0517
Plasmodium vivax hypothetical protein, conserved 0.0292 0.0365 1
Trypanosoma cruzi ISWI complex protein 0.0063 0.0051 0.0914
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Trypanosoma cruzi cytochrome P450, putative 0.0082 0.0078 0.1413
Loa Loa (eye worm) hypothetical protein 0.008 0.0075 0.0109
Echinococcus multilocularis glutamate receptor 2 0.0149 0.017 0.0168
Echinococcus multilocularis survival motor neuron protein 1 0.1546 0.2084 0.2083
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0187 0.0221 0.6049
Echinococcus multilocularis Protein lozenge 0.0117 0.0125 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.003 0.0111
Schistosoma mansoni steroid hormone receptor ad4bp 0.0033 0.001 0.0007
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0029 0.0004 0.0088
Leishmania major cytochrome p450-like protein 0.0054 0.0039 0.1039
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0187 0.0221 0.0219
Onchocerca volvulus 0.0035 0.0013 0.004
Echinococcus granulosus sodium:glucose cotransporter 0.0043 0.0024 0.0023
Plasmodium falciparum glutathione reductase 0.0029 0.0004 0.0123
Trypanosoma cruzi potassium voltage-gated channel 0.0217 0.0262 0.4772
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0027 0.0002 0.0001
Echinococcus multilocularis methyl CpG binding domain protein 2 0.007 0.0061 0.0059
Trypanosoma brucei trypanothione reductase 0.0083 0.0079 0.2133
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0662 0.0871 1
Loa Loa (eye worm) hypothetical protein 0.0292 0.0365 0.0538
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0518 0.0515
Trypanosoma brucei hypothetical protein, conserved 0.0292 0.0365 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Brugia malayi hypothetical protein 0.0114 0.0122 0.0178
Brugia malayi hypothetical protein 0.0054 0.004 0.0057
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0017 0.0426
Schistosoma mansoni hypothetical protein 0.0202 0.0242 0.024
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Loa Loa (eye worm) hypothetical protein 0.0214 0.0259 0.0381
Echinococcus multilocularis GPCR, family 2 0.0202 0.0242 0.0241
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0187 0.0221 0.082
Onchocerca volvulus 0.0029 0.0005 0.0011
Loa Loa (eye worm) carboxylesterase 0.0054 0.004 0.0057
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0083 0.0079 0.0296
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.0009 0.0145
Brugia malayi mKIAA0176 protein 0.0217 0.0262 0.0386
Schistosoma mansoni coup transcription factor 0.0033 0.001 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0441 0.0569 0.0568
Echinococcus multilocularis potassium voltage gated channel protein 0.4957 0.6757 0.6756
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) latrophilin receptor protein 2 0.0202 0.0242 0.0356
Schistosoma mansoni glutamate receptor kainate 0.0291 0.0364 0.0362
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0027 0.0002 0.0001
Echinococcus multilocularis lipoxygenase domain containing protein 0.0089 0.0087 0.0086
Onchocerca volvulus 0.0089 0.0087 0.0316
Brugia malayi Bromodomain containing protein 0.0157 0.018 0.0264
Onchocerca volvulus 0.0054 0.004 0.0139
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0106 0.011 0.1998
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0106 0.011 0.1998
Giardia lamblia Fructose-bisphosphate aldolase 0.0662 0.0871 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0033 0.001 0.0009
Giardia lamblia DNA repair protein RAD52 0.0353 0.0448 0.5136
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0002 0.0001
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0029 0.0004 0.0123
Loa Loa (eye worm) beta-lactamase 0.0292 0.0365 0.0538
Echinococcus granulosus lysine specific demethylase 5A 0.0058 0.0044 0.0043
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0441 0.0569 0.0568
Schistosoma mansoni hypothetical protein 0.0029 0.0005 0.0003
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0149 0.017 0.0168
Echinococcus granulosus methyl CpG binding domain protein 2 0.007 0.0061 0.0059
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0002 0.0002
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0187 0.0221 0.022
Plasmodium falciparum acyl-CoA synthetase 0.004 0.002 0.072
Trypanosoma brucei potassium voltage-gated channel, putative 0.0217 0.0262 0.7168
Brugia malayi O-methyltransferase family protein 0.0184 0.0217 0.0319
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0747 0.0988 0.4119
Schistosoma mansoni hypothetical protein 0.0045 0.0027 0.0024
Schistosoma mansoni zinc finger protein 0.0063 0.0051 0.0048
Schistosoma mansoni glutamate receptor NMDA 0.239 0.324 0.3239
Mycobacterium tuberculosis Probable hydrolase 0.0292 0.0365 0.1433
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0012 0.0016
Echinococcus multilocularis SAM and MBT domain containing protein 0.0104 0.0108 0.0107
Onchocerca volvulus 0.0029 0.0005 0.0011
Echinococcus granulosus arachidonate 5 lipoxygenase 0.039 0.0499 0.0498
Trypanosoma brucei protein kinase, putative 0.0106 0.011 0.2995
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0009 0.0221
Treponema pallidum bacterioferrin (TpF1) 0.0107 0.0112 0.1096
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0012 0.0011
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0027 0.0002 0.0002
Echinococcus multilocularis short transient receptor potential channel 6 0.0187 0.0221 0.022
Brugia malayi MH2 domain containing protein 0.05 0.065 0.0961
Echinococcus granulosus SAM and MBT domain containing protein 0.0104 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Brugia malayi hypothetical protein 0.0123 0.0133 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Mycobacterium ulcerans beta-lactamase 0.0292 0.0365 0.1508
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0027 0.0101
Loa Loa (eye worm) MH2 domain-containing protein 0.05 0.065 0.0961
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0017 0.0436
Brugia malayi Doublecortin family protein 0.0089 0.0087 0.0128
Entamoeba histolytica hypothetical protein 0.0114 0.0122 0.1388
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0187 0.0221 0.0219
Echinococcus multilocularis para nitrobenzyl esterase 0.0054 0.004 0.0038
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0187 0.0221 0.6053
Schistosoma mansoni ferritin 0.0107 0.0112 0.011
Echinococcus granulosus thioredoxin glutathione reductase 0.0084 0.008 0.0079
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0033 0.001 0.0009
Plasmodium falciparum protein kinase 5 0.009 0.0088 0.3339
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Trypanosoma brucei Thiopurine S-methyltransferase (TPMT), putative 0.0048 0.0031 0.0831
Echinococcus granulosus Smad4 0.0034 0.0012 0.0011
Echinococcus multilocularis geminin 0.0886 0.1179 0.1178
Trichomonas vaginalis esterase, putative 0.0292 0.0365 0.1353
Echinococcus granulosus nmda type glutamate receptor 0.2988 0.4059 0.4058
Echinococcus granulosus glutamate receptor 2 0.0441 0.0569 0.0568
Brugia malayi Importin beta-1 subunit 0.0032 0.0009 0.0012
Echinococcus multilocularis dro:myosuppressin receptor 0.0027 0.0002 0.0001
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0029 0.0004 0.0059
Echinococcus granulosus transient receptor potential cation channel 0.0187 0.0221 0.022
Schistosoma mansoni calcium-activated potassium channel 0.0428 0.0551 0.0549
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0002 0.0001
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0048 0.0031 0.0107
Echinococcus multilocularis neuropeptide FF receptor 2 0.0027 0.0002 0.0001
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0257 0.0316 0.0315
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0187 0.0221 0.0219
Trypanosoma cruzi PAB1-binding protein , putative 0.01 0.0103 0.1862
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0187 0.0221 0.0325
Echinococcus granulosus lipoxygenase domain containing protein 0.0089 0.0087 0.0086
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0054 0.0039 0.0143
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0104 0.0108 0.0106
Echinococcus multilocularis dnaJ subfamily B 0.2636 0.3576 0.3575
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0189 0.0224 0.0875
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0403 0.0518 0.0517
Echinococcus granulosus cyclin dependent kinase 5 0.009 0.0088 0.0087
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.003 0.0029
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0187 0.0221 0.0219
Schistosoma mansoni methyl-cpg binding protein mbd 0.007 0.0061 0.0058
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0009 0.021
Trypanosoma brucei cdc2-related kinase 3 0.009 0.0088 0.2393
Schistosoma mansoni hypothetical protein 0.0044 0.0025 0.0023
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0248 0.0305 0.0304
Brugia malayi Steroid receptor seven-up type 2 0.0033 0.001 0.0013
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0103 0.0106 0.0105
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0322 0.0407 0.0405
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.011 0.0108
Loa Loa (eye worm) voltage-gated potassium channel 0.0403 0.0518 0.0765
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0026 0.0098
Echinococcus granulosus para nitrobenzyl esterase 0.0054 0.004 0.0038
Echinococcus granulosus cpg binding protein 0.0234 0.0285 0.0284
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0187 0.0221 0.0812
Echinococcus granulosus voltage dependent calcium channel 0.0187 0.0221 0.022
Schistosoma mansoni smad1 5 8 and 0.0034 0.0012 0.0009
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0029 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Schistosoma mansoni metabotropic glutamate receptor 0.0149 0.017 0.0167
Brugia malayi metabotropic glutamate receptor type 2 0.0149 0.017 0.0249
Plasmodium vivax acyl-CoA synthetase, putative 0.004 0.002 0.0516
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0043 0.0024 0.0023
Schistosoma mansoni intermediate filament proteins 0.0172 0.0201 0.0199
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0025 0.0024
Mycobacterium tuberculosis Probable dehydrogenase 0.0189 0.0224 0.0875
Echinococcus granulosus orexin receptor type 2 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0027 0.0002 0.0001
Loa Loa (eye worm) heterochromatin protein 1 0.008 0.0075 0.0109
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0027 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0187 0.0221 0.0219
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Echinococcus multilocularis voltage dependent calcium channel 0.0187 0.0221 0.022
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0029 0.0005 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Loa Loa (eye worm) steroid hormone receptor 0.0033 0.001 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0054 0.0039 0.0136
Brugia malayi nuclear hormone receptor 0.0033 0.001 0.0013
Echinococcus granulosus ryanodine receptor 44f 0.0187 0.0221 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0008 0.0032
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.003 0.08
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.003 0.0532
Loa Loa (eye worm) hypothetical protein 0.0389 0.0498 0.0736
Leishmania major hypothetical protein, conserved 0.0292 0.0365 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0002 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.002 0.0076
Brugia malayi MH1 domain containing protein 0.0034 0.0012 0.0016
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0114 0.0122 0.012
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0029 0.0005 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0062
Loa Loa (eye worm) transcription factor SMAD2 0.05 0.065 0.0961
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0033 0.001 0.0013
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0062 0.0049 0.0183
Loa Loa (eye worm) hypothetical protein 0.0119 0.0128 0.0187
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0054 0.0039 0.0691
Plasmodium vivax basic transcription factor 3b, putative 0.0039 0.0018 0.0477
Echinococcus granulosus mitogen activated protein kinase 0.0106 0.011 0.0109
Brugia malayi Dopamine receptor protein 1 0.0027 0.0002 0.0002
Echinococcus multilocularis low density lipoprotein receptor protein 0.0029 0.0005 0.0004
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0054 0.0039 0.103
Echinococcus multilocularis transient receptor potential cation channel 0.0187 0.0221 0.022
Echinococcus multilocularis muscleblind protein 0.0951 0.1267 0.1266
Trypanosoma cruzi major cysteine proteinase, putative 0.0052 0.0036 0.0651
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0099
Toxoplasma gondii hypothetical protein 0.0187 0.0221 0.4034
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0518 0.0515
Trypanosoma brucei btb/poz domain containing protein, putative 0.0217 0.0262 0.7168
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0187 0.0221 0.0812
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Brugia malayi G protein-coupled receptor F59B2.13 0.0027 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0291 0.0364 0.0362
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0212 0.0255 0.2921
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0033 0.001 0.0013
Brugia malayi TAR-binding protein 0.0471 0.061 0.0902
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) MBCTL1 0.0119 0.0128 0.0187
Mycobacterium leprae PROBABLE METHYLTRANSFERASE 0.0184 0.0217 0.4831
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0747 0.0988 1
Brugia malayi neuropeptide F receptor 0.0027 0.0002 0.0002
Schistosoma mansoni chromobox protein 0.008 0.0075 0.0072
Trypanosoma cruzi cdc2-related kinase 1 0.009 0.0088 0.1598
Loa Loa (eye worm) cytochrome P450 family protein 0.0082 0.0078 0.0114
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Brugia malayi ImpB/MucB/SamB family protein 0.0045 0.0027 0.0039
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0403 0.0518 0.0765
Echinococcus multilocularis muscleblind protein 1 0.0951 0.1267 0.1266
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Toxoplasma gondii transporter, cation channel family protein 0.0187 0.0221 0.4034
Echinococcus granulosus cytochrome P450 2K1 0.0054 0.0039 0.0037
Schistosoma mansoni lamin 0.0172 0.0201 0.0199
Brugia malayi SET domain containing protein 0.0034 0.0011 0.0015
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Brugia malayi CHD4 protein 0.0033 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0322 0.0407 0.06
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0054 0.0039 0.0136
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0114 0.0121 0.044
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0212 0.0255 0.0254
Brugia malayi Protein kinase domain containing protein 0.009 0.0088 0.0129
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0033 0.001 0.0009
Onchocerca volvulus 0.0172 0.0201 0.0738
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0062
Loa Loa (eye worm) ion channel NompC 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Brugia malayi basement membrane proteoglycan precursor 0.0029 0.0005 0.0006
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0083 0.0079 0.0078
Brugia malayi photoreceptor-specific nuclear receptor 0.0033 0.001 0.0013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0066
Echinococcus granulosus chromobox protein 1 0.008 0.0075 0.0073
Echinococcus multilocularis dna polymerase eta 0.0045 0.0027 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0325 0.041 0.0408
Trypanosoma brucei cdc2-related kinase 1 0.009 0.0088 0.2393
Schistosoma mansoni voltage-dependent calcium channel 0.0187 0.0221 0.0219
Loa Loa (eye worm) cytochrome P450 0.0054 0.0039 0.0055
Loa Loa (eye worm) hypothetical protein 0.0028 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Echinococcus granulosus hypothetical protein 0.0027 0.0002 0.0001
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0114 0.0121 0.0177
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0255 0.0314 0.5751
Brugia malayi K+ channel tetramerisation domain containing protein 0.0217 0.0262 0.0386
Echinococcus granulosus ecdysone induced protein 78C 0.0033 0.001 0.0009
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0271 0.0336 0.0334
Schistosoma mansoni hypothetical protein 0.0202 0.0242 0.024
Schistosoma mansoni two-pore calcium channel 0.0187 0.0221 0.0219
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0054 0.0039 0.0136
Loa Loa (eye worm) hypothetical protein 0.0054 0.0038 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0003 0.0012
Schistosoma mansoni aldehyde dehydrogenase 0.0137 0.0153 0.015
Echinococcus granulosus expressed conserved protein 0.0099 0.0101 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0018 0.0069
Schistosoma mansoni apoferritin-2 0.0107 0.0112 0.011
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0029 0.0005 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.001 0.0009
Loa Loa (eye worm) TYRA-2 protein 0.0027 0.0002 0.0002
Plasmodium falciparum thioredoxin reductase 0.0083 0.0079 0.2976
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0054 0.0039 0.0136
Brugia malayi Cytochrome P450 family protein 0.0082 0.0078 0.0114
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0056 0.1006
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0187 0.0221 0.022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0014 0.0051
Plasmodium falciparum LCCL domain-containing protein 0.0089 0.0087 0.3309
Schistosoma mansoni ferritin 0.0107 0.0112 0.011
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0033 0.001 0.0013
Brugia malayi beta-NAC-like protein 0.0039 0.0018 0.0026
Loa Loa (eye worm) hypothetical protein 0.0403 0.0518 0.0765
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0054 0.0039 0.0143
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0106 0.011 0.1998
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0029 0.0004 0.0088
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0033 0.001 0.0009
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0403 0.0518 0.0517
Schistosoma mansoni hypothetical protein 0.0031 0.0008 0.0006
Brugia malayi Carboxylesterase family protein 0.0322 0.0407 0.06
Loa Loa (eye worm) PHD-finger family protein 0.0084 0.0081 0.0118
Echinococcus multilocularis sodium channel protein 0.0187 0.0221 0.022
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0054 0.004 0.014
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0002 0.0001
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0344 0.0436 0.0644
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.001 0.0013
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0044 0.0064
Schistosoma mansoni calcium-activated potassium channel 0.0187 0.0221 0.0219
Brugia malayi beta-lactamase 0.0292 0.0365 0.0538
Brugia malayi Pre-SET motif family protein 0.0255 0.0314 0.0464
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0187 0.0221 0.022
Brugia malayi Transient-receptor-potential like protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0202 0.0242 0.0356
Leishmania major basic transcription factor 3a, putative 0.0039 0.0018 0.0488
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.009 0.0088 0.0087
Loa Loa (eye worm) Smad1 0.0034 0.0012 0.0016
Echinococcus multilocularis serotonin receptor 0.0027 0.0002 0.0001
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0187 0.0221 0.0325
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.0049 0.0183
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0033 0.001 0.0007
Echinococcus multilocularis BTB:POZ domain containing protein KCTD16 0.0217 0.0262 0.0261
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.021 0.0253 0.099
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0033 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0088 0.0086 0.0125
Brugia malayi hypothetical protein 0.0929 0.1238 0.1831
Brugia malayi O-methyltransferase 0.0184 0.0217 0.0319
Schistosoma mansoni calcium-activated potassium channel 0.0407 0.0523 0.052
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0002 0.0001
Schistosoma mansoni 60S ribosomal protein L21 0.0187 0.0221 0.0219
Echinococcus multilocularis tar DNA binding protein 0.0471 0.061 0.0609
Brugia malayi neuropeptide F receptor 0.0027 0.0002 0.0002
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0291 0.0364 0.0363
Echinococcus granulosus potassium voltage gated channel protein 0.0403 0.0518 0.0517
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus Protein patched homolog 1 0.0045 0.0027 0.0026
Entamoeba histolytica cell division protein kinase 2, putative 0.009 0.0088 0.1003
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0027 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0214 0.0258 0.0256
Echinococcus multilocularis expressed conserved protein 0.0099 0.0101 0.01
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0187 0.0221 0.0219
Echinococcus multilocularis expressed protein 0.0107 0.0112 0.0111
Schistosoma mansoni rab6-interacting 0.0089 0.0087 0.0085
Trypanosoma cruzi cdc2-related kinase 3 0.009 0.0088 0.1598
Echinococcus granulosus g protein coupled receptor 0.0027 0.0002 0.0001
Echinococcus multilocularis polycomb protein SCMH1 0.0104 0.0108 0.0107
Trichomonas vaginalis hypothetical protein 0.0026 0.0001 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.009 0.0088 0.0129
Onchocerca volvulus 0.0028 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Brugia malayi hypothetical protein 0.0089 0.0087 0.0128
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.6171 0.842 0.842
Echinococcus granulosus small conductance calcium activated potassium 0.0428 0.0551 0.055
Leishmania major hypothetical protein, conserved 0.0187 0.0221 0.6053
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0027 0.0002 0.0002
Plasmodium vivax protein kinase Crk2 0.009 0.0088 0.2393
Schistosoma mansoni gliotactin 0.0054 0.004 0.0037
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.004 0.002 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0019 0.0069
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0009 0.0006
Echinococcus granulosus BC026374 protein S09 family 0.0054 0.004 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0217 0.0262 0.4772
Loa Loa (eye worm) melatonin receptor type 1A 0.0027 0.0002 0.0002
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0043 0.0024 0.0023
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Schistosoma mansoni hypothetical protein 0.0054 0.0039 0.0036
Echinococcus granulosus atrial natriuretic peptide receptor 0.0149 0.017 0.0168
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0147 0.0166 0.0165
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.009 0.0088 0.1596
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Schistosoma mansoni jumonji domain containing protein 0.0082 0.0077 0.0075
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0066
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0054 0.0038 0.0143
Brugia malayi Receptor family ligand binding region containing protein 0.0149 0.017 0.0249
Mycobacterium tuberculosis Probable lipase LipD 0.0292 0.0365 0.1433
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0054 0.0039 0.0143
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Conserved protein 0.0292 0.0365 0.1433
Brugia malayi GH02984p 0.0389 0.0498 0.0736
Echinococcus granulosus hypothetical protein 0.0187 0.0221 0.022
Entamoeba histolytica hypothetical protein 0.0033 0.001 0.0109
Echinococcus granulosus two pore calcium channel protein 2 0.0187 0.0221 0.022
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0137 0.0153 0.0152
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0054 0.0038 0.0136
Brugia malayi Carboxylesterase family protein 0.0322 0.0407 0.06
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0001 0.0003
Schistosoma mansoni ferritin light chain 0.0107 0.0112 0.011
Schistosoma mansoni lamin 0.0172 0.0201 0.0199
Echinococcus granulosus somatostatin receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) cytochrome P450 family protein 0.0178 0.0209 0.0307
Onchocerca volvulus 0.0104 0.0108 0.0392
Mycobacterium ulcerans glutaminase 0.0306 0.0384 0.1591
Echinococcus granulosus potassium large conductance calcium activated 0.0187 0.0221 0.022
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0104 0.0108 0.0392
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0009 0.0011
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0441 0.0569 0.0568
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0217 0.0262 0.0386
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0187 0.0221 0.022
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0187 0.0221 0.022
Schistosoma mansoni hypothetical protein 0.0886 0.1179 0.1177
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0518 0.0515
Onchocerca volvulus 0.0149 0.017 0.0621
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0027 0.0002 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0325 0.041 0.0408
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0002 0.0001
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0187 0.0221 0.022
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0441 0.0569 0.0568
Schistosoma mansoni hypothetical protein 0.0202 0.0242 0.024
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0004 0.0066
Schistosoma mansoni sex comb on midleg homolog 0.0104 0.0108 0.0106
Loa Loa (eye worm) hypothetical protein 0.0045 0.0026 0.0037
Brugia malayi CXXC zinc finger family protein 0.0214 0.0258 0.038
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0009 0.0008
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0104 0.0108 0.0107
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0187 0.0221 0.0219
Loa Loa (eye worm) hypothetical protein 0.0083 0.0079 0.0115
Echinococcus granulosus sodium leak channel non selective protein 0.0187 0.0221 0.022
Schistosoma mansoni ryanodine receptor related 0.0187 0.0221 0.0219
Brugia malayi G protein-coupled receptor 0.0027 0.0002 0.0002
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0027 0.0002 0.0001
Echinococcus granulosus voltage gated potassium channel 0.0187 0.0221 0.022
Echinococcus granulosus transient receptor potential cation channel 0.0187 0.0221 0.022
Plasmodium vivax glutathione reductase, putative 0.0083 0.0079 0.2133
Echinococcus granulosus histone acetyltransferase MYST2 0.0119 0.0128 0.0127
Brugia malayi K+ channel tetramerisation domain containing protein 0.0217 0.0262 0.0386
Brugia malayi O-methyltransferase family protein 0.0184 0.0217 0.0319
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0029 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0217 0.0262 0.0386
Mycobacterium ulcerans methyltransferase 0.0184 0.0217 0.089
Echinococcus multilocularis hyperpolarization activated cyclic 0.0187 0.0221 0.022
Echinococcus granulosus two pore calcium channel protein 1 0.0187 0.0221 0.022
Loa Loa (eye worm) mbt repeat family protein 0.0104 0.0108 0.0158
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0033 0.001 0.0009
Trypanosoma cruzi cruzipain precursor, putative 0.0066 0.0056 0.1006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) doublecortin family protein 0.0089 0.0087 0.0128
Echinococcus multilocularis transcription factor Dp 1 0.0123 0.0133 0.0132
Trypanosoma brucei cytochrome P450, putative 0.0082 0.0078 0.2115
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0212 0.0255 0.4652
Echinococcus multilocularis carboxylesterase 5A 0.0322 0.0407 0.0406
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0002 0.0001
Onchocerca volvulus 0.0292 0.0365 0.1346
Echinococcus granulosus fmrfamide receptor 0.0027 0.0002 0.0001
Brugia malayi G-protein coupled receptor 0.0027 0.0002 0.0002
Echinococcus granulosus nmda type glutamate receptor 0.2099 0.2841 0.284
Echinococcus multilocularis hyperpolarization activated cyclic 0.0187 0.0221 0.022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.001 0.0013
Brugia malayi Carboxylesterase family protein 0.0054 0.004 0.0057
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Onchocerca volvulus 0.0184 0.0217 0.0797
Trypanosoma cruzi hypothetical protein, conserved 0.0292 0.0365 0.6654
Echinococcus multilocularis transient receptor potential cation channel 0.0187 0.0221 0.022
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0009 0.0008
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0028 0.0004 0.0004
Echinococcus granulosus intermediate filament protein 0.0172 0.0201 0.02
Onchocerca volvulus 0.0172 0.0201 0.0738
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0323 0.0408 0.1605
Loa Loa (eye worm) hypothetical protein 0.0056 0.0041 0.0059
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0149 0.017 0.0249
Echinococcus granulosus potassium voltage gated channel subfamily A 0.4957 0.6757 0.6756
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0187 0.0221 0.0325
Echinococcus granulosus sodium:myo inositol cotransporter 0.0043 0.0024 0.0023
Mycobacterium ulcerans hypothetical protein 0.0292 0.0365 0.1508
Onchocerca volvulus 0.0217 0.0262 0.0965
Schistosoma mansoni glutamate receptor kainate 0.0291 0.0364 0.0362
Echinococcus multilocularis tyrosine kinase 0.0149 0.017 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0088 0.0086
Brugia malayi Cytochrome P450 family protein 0.0082 0.0078 0.0114
Loa Loa (eye worm) hypothetical protein 0.0217 0.0262 0.0386
Echinococcus multilocularis Smad4 0.0034 0.0012 0.0011
Brugia malayi Serotonin receptor 0.0027 0.0002 0.0002
Echinococcus granulosus tachykinin peptides receptor 99D 0.0027 0.0002 0.0001
Brugia malayi Serotonin receptor 0.0027 0.0002 0.0002
Echinococcus multilocularis g-protein coupled receptor 0.0027 0.0002 0.0001
Schistosoma mansoni tyrosine kinase 0.0149 0.017 0.0167
Echinococcus multilocularis conserved hypothetical protein 0.0187 0.0221 0.022
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0027 0.0002 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Echinococcus granulosus tyrosine kinase 0.0149 0.017 0.0168
Brugia malayi hypothetical protein 0.1546 0.2084 0.3083
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0187 0.0221 0.0325
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0187 0.0221 0.022
Trypanosoma brucei btb/poz domain containing protein, putative 0.0217 0.0262 0.7168
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0212 0.0255 0.0376
Echinococcus multilocularis FTZ F1 alpha 0.0033 0.001 0.0009
Brugia malayi RNA recognition motif domain containing protein 0.0471 0.061 0.0902
Loa Loa (eye worm) hypothetical protein 0.0169 0.0197 0.029
Brugia malayi hypothetical protein 0.0028 0.0004 0.0004
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0187 0.0221 0.022
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0045 0.0027 0.0026
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0107 0.0112 0.011
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.0027 0.0026
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0029 0.0005 0.0006
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0029 0.0004 0.0002
Onchocerca volvulus 0.0054 0.0038 0.0134
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Toxoplasma gondii cytochrome p450 superfamily protein 0.0054 0.0039 0.0687
Onchocerca volvulus 0.0292 0.0365 0.1346
Echinococcus multilocularis Polycystic kidney disease protein 0.0089 0.0087 0.0086
Brugia malayi Bromodomain containing protein 0.0319 0.0402 0.0594
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0202 0.0242 0.0241
Echinococcus multilocularis smad 0.0034 0.0012 0.0011
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0054 0.0039 0.0143
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0202 0.0242 0.0241
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Leishmania major hypothetical protein, conserved 0.0217 0.0262 0.7171
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0082 0.0078 0.0308
Echinococcus multilocularis neuropeptide s receptor 0.0027 0.0002 0.0001
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0291 0.0364 0.0363
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0187 0.0221 0.022
Leishmania major cathepsin L-like protease 0.0066 0.0056 0.1513
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0187 0.0221 0.0219
Echinococcus granulosus carboxylesterase 5A 0.0322 0.0407 0.0406
Onchocerca volvulus Arrow homolog 0.0029 0.0005 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Onchocerca volvulus 0.0054 0.004 0.0139
Echinococcus granulosus importin subunit beta 1 0.0032 0.0009 0.0008
Echinococcus granulosus g protein coupled receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Brugia malayi Muscleblind-like protein 0.0951 0.1267 0.1874
Brugia malayi MAP kinase sur-1 0.0106 0.011 0.0161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Entamoeba histolytica cell division protein kinase 2, putative 0.009 0.0088 0.1003
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0002 0.0001
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0187 0.0221 0.022
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Loa Loa (eye worm) CYP4Cod1 0.0082 0.0078 0.0114
Brugia malayi Glutamate receptor 1 precursor 0.0291 0.0364 0.0537
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Trypanosoma brucei BTB/POZ domain/Regulator of chromosome condensation (RCC1) repeat, putative 0.0217 0.0262 0.7168
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0012 0.0016
Brugia malayi CHE-14 protein 0.0045 0.0027 0.0038
Echinococcus granulosus transient receptor potential cation channel 0.0187 0.0221 0.022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.0049 0.0183
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0403 0.0518 0.0765
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0008 0.0031
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0033 0.001 0.0009
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0001 0.0004
Echinococcus granulosus g-protein coupled receptor 0.0027 0.0002 0.0001
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0187 0.0221 0.022
Mycobacterium ulcerans fatty-acid-CoA ligase 0.004 0.002 0.0065
Echinococcus multilocularis snurportin 1 0.0344 0.0436 0.0435
Brugia malayi Smad1 0.0034 0.0012 0.0016
Trichomonas vaginalis ferritin, putative 0.0107 0.0112 0.0416
Echinococcus multilocularis potassium voltage gated channel protein 0.0403 0.0518 0.0517
Loa Loa (eye worm) hypothetical protein 0.0289 0.0362 0.0533
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0033 0.001 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0029 0.0005 0.0003
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0291 0.0364 0.0363
Onchocerca volvulus 0.0034 0.0011 0.0034
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0029 0.0005 0.0003
Brugia malayi cation channel family protein 0.0187 0.0221 0.0325
Brugia malayi Heterochromatin protein 1 0.008 0.0075 0.0109
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0119 0.0128 0.0127
Toxoplasma gondii thioredoxin reductase 0.0083 0.0079 0.1423
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Loa Loa (eye worm) glutamate receptor 0.0149 0.017 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0033 0.001 0.0013
Loa Loa (eye worm) potassium channel tetramerisation domain containing 3 0.0217 0.0262 0.0386
Brugia malayi intermediate filament protein 0.0172 0.0201 0.0296
Leishmania major cathepsin L-like protease 0.0066 0.0056 0.1513
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.003 0.0006 0.0005
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0292 0.0365 0.0538
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0026 0.0098
Echinococcus multilocularis chromobox protein 1 0.008 0.0075 0.0073
Schistosoma mansoni microtubule-associated protein tau 0.7324 1 1
Trypanosoma cruzi ISWI complex protein 0.0063 0.0051 0.0914
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0005 0.0003
Mycobacterium ulcerans lipase LipD 0.0292 0.0365 0.1508
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.009 0.0088 0.2402
Schistosoma mansoni hypothetical protein 0.0063 0.0051 0.0048
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Probable catechol-O-methyltransferase 0.1588 0.2141 0.8499
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0009 0.014
Trypanosoma brucei Thiopurine S-methyltransferase (TPMT), putative 0.0048 0.0031 0.0831
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0038 0.0017 0.005
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) intermediate filament protein 0.0172 0.0201 0.0296
Loa Loa (eye worm) runx1 0.0117 0.0125 0.0183
Brugia malayi Sodium:solute symporter family protein 0.0043 0.0024 0.0033
Loa Loa (eye worm) hypothetical protein 0.0149 0.017 0.0249
Schistosoma mansoni high-affinity choline transporter 0.0389 0.0498 0.0496
Trypanosoma brucei DNA polymerase eta, putative 0.0045 0.0027 0.0716
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Onchocerca volvulus Huntingtin homolog 0.0123 0.0133 0.0487
Loa Loa (eye worm) hypothetical protein 0.0929 0.1238 0.1831
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0441 0.0569 0.0568
Schistosoma mansoni hypothetical protein 0.0638 0.084 0.0838
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0054 0.0039 0.0136
Entamoeba histolytica hypothetical protein 0.0114 0.0122 0.1388
Schistosoma mansoni smad1 5 8 and 0.0034 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Echinococcus multilocularis RUN 0.0089 0.0087 0.0086
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0268 0.0332 0.033
Schistosoma mansoni RAR-like nuclear receptor 0.0033 0.001 0.0007
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0212 0.0255 0.6992
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0217 0.0262 0.4772
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0639 0.084 0.1242
Schistosoma mansoni sex comb on midleg homolog 0.0104 0.0108 0.0106
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0212 0.0255 0.0253
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0187 0.0221 0.022
Plasmodium vivax SET domain protein, putative 0.0255 0.0314 0.8623
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0248 0.0305 0.0304
Onchocerca volvulus 0.0058 0.0044 0.0155
Brugia malayi ion channel NompC 0.0187 0.0221 0.0325
Entamoeba histolytica transcription factor BTF3, putative 0.0039 0.0018 0.0204
Echinococcus granulosus zinc finger protein 0.0092 0.0091 0.009
Echinococcus multilocularis transient receptor potential gamma protein 0.0187 0.0221 0.022
Schistosoma mansoni methyl-cpg binding protein mbd 0.007 0.0061 0.0058
Loa Loa (eye worm) hypothetical protein 0.0428 0.0551 0.0814
Echinococcus multilocularis cyclin dependent kinase 1 0.009 0.0088 0.0087
Leishmania major 4-coumarate:coa ligase-like protein 0.0054 0.0038 0.1037
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0187 0.0221 0.022
Schistosoma mansoni hypothetical protein 0.2636 0.3576 0.3575
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus tumor protein p63 0.1482 0.1995 0.1995
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0187 0.0221 0.4034
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0292 0.0365 0.0538
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0403 0.0518 0.0517
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0403 0.0518 0.0517
Brugia malayi PHD-finger family protein 0.0114 0.0121 0.0178
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0054 0.0039 0.0136
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0257 0.0316 0.0315
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0114 0.0122 0.0119
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0008 0.0188
Onchocerca volvulus 0.0058 0.0044 0.0155
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0292 0.0365 0.1508
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0441 0.0569 0.0568
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0323 0.0408 0.1689
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Brugia malayi jmjC domain containing protein 0.0058 0.0044 0.0064
Loa Loa (eye worm) Kv4.2 voltage-gated potassium channel 0.0217 0.0262 0.0386
Echinococcus granulosus alpha 1A adrenergic receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0437 0.0563 0.0561
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Brugia malayi voltage-dependent calcium channel 0.0187 0.0221 0.0325
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0001 0.0007
Loa Loa (eye worm) glutamate receptor 1 0.0291 0.0364 0.0537
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0187 0.0221 0.0325
Echinococcus granulosus 7tm_1 domain containing protein 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0054 0.0039 0.0136
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0029 0.0005 0.0006
Brugia malayi MH1 domain containing protein 0.0034 0.0012 0.0016
Leishmania major hypothetical protein, conserved 0.0063 0.0051 0.1374
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0009 0.0146
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0292 0.0365 0.6654
Loa Loa (eye worm) calcium binding EGF domain-containing protein 0.0029 0.0005 0.0006
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0054 0.004 0.0037
Echinococcus granulosus short transient receptor potential channel 6 0.0187 0.0221 0.022
Echinococcus multilocularis cyclin dependent kinase 1 0.009 0.0088 0.0087
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0217 0.0262 1
Loa Loa (eye worm) hypothetical protein 0.0929 0.1238 0.1831
Echinococcus multilocularis transfer RNA-Gly 0.0403 0.0518 0.0517
Toxoplasma gondii transporter, cation channel family protein 0.0187 0.0221 0.4034
Loa Loa (eye worm) hypothetical protein 0.0639 0.084 0.1242
Brugia malayi cation channel family protein 0.0187 0.0221 0.0325
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0292 0.0365 0.0538
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0189 0.0224 0.0875
Echinococcus multilocularis small conductance calcium activated potassium 0.0428 0.0551 0.055
Brugia malayi beta-lactamase family protein 0.0292 0.0365 0.0538
Brugia malayi PHD-finger family protein 0.003 0.0006 0.0008
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0054 0.0039 0.0143
Schistosoma mansoni hypothetical protein 0.0315 0.0397 0.0395
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0004 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0033 0.001 0.0013
Onchocerca volvulus 0.0029 0.0005 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0054 0.0039 0.0136
Echinococcus granulosus low density lipoprotein receptor ldl 0.0029 0.0005 0.0004
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0054 0.0039 0.0143
Echinococcus granulosus calcium activated potassium channel 0.0189 0.0224 0.0222
Loa Loa (eye worm) hypothetical protein 0.0106 0.011 0.0161
Schistosoma mansoni tar DNA-binding protein 0.0471 0.061 0.0608
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Echinococcus multilocularis nmda type glutamate receptor 0.2988 0.4059 0.4058
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.01 0.0103 0.015
Schistosoma mansoni voltage-gated potassium channel 0.0403 0.0518 0.0515
Trichomonas vaginalis spcc417.12 protein, putative 0.0054 0.004 0.0147
Plasmodium falciparum zinc finger protein, putative 0.0033 0.001 0.0349
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0018 0.0069
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.011 0.0408
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0009 0.0219
Loa Loa (eye worm) hypothetical protein 0.0058 0.0044 0.0064
Echinococcus granulosus dro:myosuppressin receptor 0.0027 0.0002 0.0001
Trichomonas vaginalis helicase, putative 0.0048 0.0031 0.0116
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0054 0.0039 0.0136
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0189 0.0224 0.0875
Brugia malayi Intermediate filament tail domain containing protein 0.0172 0.0201 0.0296
Schistosoma mansoni ferritin light chain 0.0107 0.0112 0.011
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0137 0.0153 0.4177
Schistosoma mansoni sodium/solute symporter 0.0043 0.0024 0.0021
Trypanosoma cruzi Thiopurine S-methyltransferase (TPMT), putative 0.0048 0.0031 0.0559
Schistosoma mansoni smad1 5 8 and 0.0034 0.0012 0.0009
Leishmania major cathepsin L-like protease 0.0066 0.0056 0.1513
Brugia malayi RNA, U transporter 1 0.0092 0.0091 0.0132
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0009 0.0011
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0106 0.011 0.2995
Echinococcus multilocularis transient receptor potential cation channel 0.0187 0.0221 0.022
Brugia malayi Cyclic-nucleotide gated cation channel 0.0187 0.0221 0.0325
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0292 0.0365 0.0362
Loa Loa (eye worm) TAR-binding protein 0.0471 0.061 0.0902
Echinococcus multilocularis lipoxygenase domain containing protein 0.0089 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0187 0.0221 0.0325
Echinococcus granulosus GPCR family 2 0.0202 0.0242 0.0241
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0107 0.0112 0.1995
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus transcription factor Dp 1 0.0123 0.0133 0.0132
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0004 0.0088
Onchocerca volvulus 0.0054 0.004 0.0139
Loa Loa (eye worm) hypothetical protein 0.0089 0.0087 0.0128
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0029 0.0005 0.0004
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0187 0.0221 0.0325
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0217 0.0262 0.4772
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0187 0.0221 0.4028
Schistosoma mansoni potassium channel tetramerization domain-containing 0.0217 0.0262 0.0259
Schistosoma mansoni hypothetical protein 0.0089 0.0087 0.0085
Brugia malayi AMP-binding enzyme family protein 0.0054 0.0038 0.0055
Brugia malayi MH2 domain containing protein 0.0034 0.0012 0.0016
Echinococcus multilocularis glutamate receptor 2 0.0291 0.0364 0.0363
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0403 0.0518 0.0517
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.003 0.0042
Schistosoma mansoni voltage-gated potassium channel 0.0217 0.0262 0.0259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.003 0.0111
Brugia malayi PHD-finger family protein 0.0031 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0292 0.0365 0.0538
Echinococcus granulosus potassium voltage gated channel protein 0.0403 0.0518 0.0517
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0103 0.0106 0.0105
Echinococcus granulosus dnaJ subfamily B 0.2636 0.3576 0.3575
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1863 0.2518 1
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Brugia malayi Cation transporter family protein 0.0058 0.0044 0.0064
Schistosoma mansoni nuclear hormone receptor 0.0033 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Trypanosoma cruzi PAB1-binding protein , putative 0.01 0.0103 0.1862
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0291 0.0364 0.0363
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0255 0.0314 0.0313
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0009 0.0008
Echinococcus multilocularis transient receptor potential cation channel 0.0187 0.0221 0.022
Echinococcus granulosus muscleblind protein 0.0951 0.1267 0.1266
Echinococcus granulosus transient receptor potential cation channel 0.0187 0.0221 0.022
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0325 0.041 0.0605
Plasmodium vivax ataxin-2 like protein, putative 0.01 0.0103 0.279
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0187 0.0221 0.0325
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0187 0.0221 0.0219
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0033 0.001 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0033 0.001 0.0013
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0029 0.0005 0.0006
Echinococcus granulosus TRP transient receptor potential channel 0.0187 0.0221 0.022
Plasmodium falciparum thioredoxin reductase 0.0029 0.0004 0.0123
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0018
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0325 0.041 0.0409
Echinococcus granulosus low density lipoprotein receptor ldl 0.0029 0.0005 0.0004
Brugia malayi hypothetical protein 0.0065 0.0054 0.0078
Echinococcus multilocularis cyclin dependent kinase 0.009 0.0088 0.0087
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0029 0.0005 0.0004
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0054 0.0039 0.0136
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0026 0.009
Echinococcus granulosus Polycystic kidney disease protein 0.0089 0.0087 0.0086
Brugia malayi hypothetical protein 0.01 0.0103 0.015
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.003 0.0006 0.0005
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0107 0.0112 0.0429
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1751 0.2364 0.3497
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0054 0.004 0.0037
Brugia malayi SET domain containing protein 0.0027 0.0002 0.0001
Echinococcus granulosus hyperpolarization activated cyclic 0.0187 0.0221 0.022
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0002 0.0001
Schistosoma mansoni retinoic acid receptor RXR 0.0033 0.001 0.0007
Schistosoma mansoni neuroligin 3 (S09 family) 0.0054 0.004 0.0037
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0187 0.0221 0.0325
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0029 0.0004 0.0003
Schistosoma mansoni ATP-binding cassette transporter 0.0291 0.0364 0.0362
Loa Loa (eye worm) histone methyltransferase 0.0075 0.0068 0.0099
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0066
Schistosoma mansoni zinc finger protein 0.0092 0.0091 0.0089
Loa Loa (eye worm) hypothetical protein 0.1546 0.2084 0.3083
Leishmania major trypanothione reductase 0.0083 0.0079 0.2142
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0639 0.084 0.1242
Mycobacterium ulcerans bacterioferritin BfrA 0.0107 0.0112 0.0451
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0009 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0054 0.0038 0.0143
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0463 0.0599 0.0597
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0187 0.0221 0.0219
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0187 0.0221 0.0325
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0088 0.0327
Echinococcus granulosus receptor type guanylyl cyclase 0.0149 0.017 0.0168
Plasmodium falciparum importin beta, putative 0.0032 0.0009 0.0306
Plasmodium falciparum ataxin-2 like protein, putative 0.01 0.0103 0.3892
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0013 0.0222
Echinococcus multilocularis cyclin dependent kinase 5 0.009 0.0088 0.0087
Echinococcus granulosus metabotropic glutamate receptor 2 0.0149 0.017 0.0168
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0008 0.0007
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0747 0.0988 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0066
Echinococcus granulosus Niemann Pick C1 protein 0.0151 0.0172 0.0171
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0106 0.011 0.1998
Brugia malayi CUB domain containing protein 0.0029 0.0005 0.0006
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0099
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.001 0.0009
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0187 0.0221 0.022
Brugia malayi Metabotropic glutamate receptor precursor. 0.0149 0.017 0.0249
Echinococcus granulosus short transient receptor potential channel 6 0.0187 0.0221 0.022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0062 0.0049 0.0183
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0043 0.0024 0.0415
Echinococcus granulosus glutamate NMDA receptor subunit 0.0291 0.0364 0.0363
Schistosoma mansoni cpg binding protein 0.0234 0.0285 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0062
Echinococcus granulosus neuroligin 0.0054 0.004 0.0038
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0054 0.0039 0.0143
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus multilocularis shaker cognate 0.0403 0.0518 0.0517
Echinococcus multilocularis voltage gated potassium channel 0.0187 0.0221 0.022
Leishmania major DNA polymerase eta, putative 0.0032 0.0009 0.0218
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0187 0.0221 0.022
Echinococcus multilocularis G protein coupled receptor 139 0.0027 0.0002 0.0001
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0662 0.0871 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0033 0.001 0.0013
Echinococcus granulosus glutamate receptor subunit protein glur 0.0291 0.0364 0.0363
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.001 0.0009
Echinococcus granulosus low density lipoprotein receptor protein 0.0029 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Echinococcus granulosus glutamate receptor NMDA 0.195 0.2636 0.2635
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Mycobacterium tuberculosis Probable esterase LipL 0.0292 0.0365 0.1433
Echinococcus granulosus metabotropic glutamate receptor 5 0.0149 0.017 0.0168
Echinococcus granulosus neuropeptide s receptor 0.0027 0.0002 0.0001
Echinococcus multilocularis acetylcholinesterase 0.0322 0.0407 0.0406
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0054 0.0039 0.0136
Echinococcus multilocularis lamin 0.0172 0.0201 0.02
Onchocerca volvulus 0.0054 0.004 0.0139
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0062 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0104 0.0108 0.0158
Onchocerca volvulus 0.0187 0.0221 0.0812
Echinococcus multilocularis transient receptor potential cation channel 0.0187 0.0221 0.022
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Onchocerca volvulus 0.0217 0.0262 0.0963
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0056 0.1006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Mycobacterium leprae Conserved hypothetical protein 0.0054 0.0039 0.0002
Schistosoma mansoni hypothetical protein 0.0428 0.0551 0.0549
Entamoeba histolytica acyl-coA synthetase, putative 0.0054 0.0038 0.0433
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0187 0.0221 0.0219
Schistosoma mansoni transient receptor potential channel 4 0.0187 0.0221 0.0219
Leishmania major cytochrome p450-like protein 0.0054 0.0039 0.1039
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.0049 0.0183
Trichomonas vaginalis penicillin-binding protein, putative 0.0292 0.0365 0.1353
Mycobacterium tuberculosis Probable lipase LipE 0.0292 0.0365 0.1433
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0221 0.0219
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0217 0.0262 0.4772
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0018 0.0324
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0149 0.017 0.0168
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0009 0.0018
Echinococcus granulosus acetylcholinesterase 0.0322 0.0407 0.0406
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0009 0.0294
Brugia malayi Carboxylesterase family protein 0.0054 0.004 0.0057
Loa Loa (eye worm) RGC/RGC protein kinase 0.0149 0.017 0.0249
Echinococcus multilocularis potassium voltage gated channel protein 0.0187 0.0221 0.022
Schistosoma mansoni tar DNA-binding protein 0.0471 0.061 0.0608
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0017 0.0062
Leishmania major hypothetical protein, conserved 0.01 0.0103 0.2798
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0217 0.0262 0.4772
Brugia malayi MH2 domain containing protein 0.0034 0.0012 0.0016
Schistosoma mansoni glutamate receptor NMDA 0.0291 0.0364 0.0362
Brugia malayi Calcitonin receptor-like protein seb-1 0.0639 0.084 0.1242
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.003 0.0042
Loa Loa (eye worm) RGC/RGC protein kinase 0.0149 0.017 0.0249
Echinococcus granulosus BTB:POZ domain containing protein 0.0217 0.0262 0.0261
Loa Loa (eye worm) hypothetical protein 0.004 0.002 0.0028
Loa Loa (eye worm) hypothetical protein 0.0157 0.018 0.0265
Echinococcus multilocularis mitogen activated protein kinase 3 0.0106 0.011 0.0109
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0009 0.0138
Echinococcus multilocularis solute carrier family 5 0.0043 0.0024 0.0023
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0119 0.0128 0.0127
Echinococcus multilocularis voltage gated potassium channel 0.0403 0.0518 0.0517
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0009 0.0147
Loa Loa (eye worm) calcium channel 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Schistosoma mansoni SET domain protein 0.0034 0.0011 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0031 0.0115
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0106 0.011 0.0161
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0002 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0471 0.061 0.0608
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0002 0.0001
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0027 0.0002 0.0001
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0054 0.0039 0.0143
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0149 0.017 0.0249
Loa Loa (eye worm) hypothetical protein 0.4957 0.6757 1
Loa Loa (eye worm) ICD-1 protein 0.0039 0.0018 0.0026
Schistosoma mansoni voltage-gated cation channel 0.0187 0.0221 0.0219
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0187 0.0221 0.0325
Plasmodium falciparum phd finger protein, putative 0.0031 0.0008 0.0262
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.1038 0.1387 0.1386
Echinococcus multilocularis serotonin receptor 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.0013
Trypanosoma brucei btb/poz domain containing protein, putative 0.0217 0.0262 0.7168
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0054 0.0038 0.0136
Trichomonas vaginalis D-aminoacylase, putative 0.0292 0.0365 0.1353
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0054 0.0039 0.0143
Schistosoma mansoni tar DNA-binding protein 0.0471 0.061 0.0608
Schistosoma mansoni thyroid hormone receptor 0.0033 0.001 0.0007
Loa Loa (eye worm) acetylcholinesterase 1 0.0322 0.0407 0.06
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0441 0.0569 0.0568
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Loa Loa (eye worm) hypothetical protein 0.004 0.002 0.0028
Echinococcus granulosus geminin 0.0886 0.1179 0.1178
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0013 0.0049
Echinococcus granulosus histone lysine methyltransferase setb 0.0325 0.041 0.0409
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0056 0.1503
Brugia malayi Thioredoxin reductase 0.0083 0.0079 0.0115
Plasmodium falciparum basic transcription factor 3b, putative 0.0039 0.0018 0.0666
Schistosoma mansoni chromobox protein 0.008 0.0075 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0033 0.001 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0033 0.001 0.0013
Brugia malayi steroid hormone receptor 0.0033 0.001 0.0013
Trichomonas vaginalis penicillin-binding protein, putative 0.0292 0.0365 0.1353
Loa Loa (eye worm) CHromoDomain protein family member 0.0033 0.001 0.0014
Loa Loa (eye worm) voltage-gated calcium channel 0.0187 0.0221 0.0325
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0662 0.0871 0.3235
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0006
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0187 0.0221 0.082
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0033 0.001 0.0013
Onchocerca volvulus 0.0029 0.0005 0.0011
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0054 0.0039 0.0143
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.001 0.0007
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0054 0.0039 0.0136
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0187 0.0221 0.022
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0189 0.0224 0.5033
Onchocerca volvulus Bile acid receptor homolog 0.0033 0.001 0.0028
Echinococcus granulosus high affinity choline transporter 1 0.0389 0.0498 0.0497
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0033 0.001 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0002 0.0001
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0187 0.0221 0.0325
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.009 0.0088 0.0129
Brugia malayi cell division control protein 2 homolog 0.009 0.0088 0.0129
Loa Loa (eye worm) glutathione reductase 0.0083 0.0079 0.0115
Schistosoma mansoni aldehyde dehydrogenase 0.0137 0.0153 0.015
Loa Loa (eye worm) hypothetical protein 0.0031 0.0008 0.001
Onchocerca volvulus 0.0315 0.0397 0.1467
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0054 0.0039 0.0143
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0009 0.0008
Brugia malayi Tachykinin-like peptides receptor 99D 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0089 0.0087 0.0128
Schistosoma mansoni hypothetical protein 0.0084 0.0081 0.0078
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0009 0.0147
Leishmania major hypothetical protein, unknown function 0.0187 0.0221 0.6053
Brugia malayi ORL1-like opioid receptor 0.0027 0.0002 0.0002
Loa Loa (eye worm) thioredoxin reductase 0.0083 0.0079 0.0115
Trypanosoma cruzi cdc2-related kinase 3 0.009 0.0088 0.1598
Schistosoma mansoni hypothetical protein 0.0044 0.0025 0.0023
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0029 0.0004 0.0088
Brugia malayi Melatonin receptor type 1A 0.0027 0.0002 0.0002
Schistosoma mansoni myst-related protein 0.0033 0.001 0.0008
Echinococcus granulosus tar DNA binding protein 0.0471 0.061 0.0609
Onchocerca volvulus 0.0184 0.0217 0.0797
Brugia malayi RNA binding protein 0.0471 0.061 0.0902
Echinococcus granulosus FTZ F1 alpha 0.0033 0.001 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0471 0.061 0.0608
Treponema pallidum fructose-bisphosphate aldolase 0.0662 0.0871 0.8814
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0292 0.0365 0.0362
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.0027 0.0026
Echinococcus granulosus serotonin receptor 0.0027 0.0002 0.0001
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0033 0.001 0.0007
Toxoplasma gondii kelch repeat and K+ channel tetramerisation domain containing protein 0.0217 0.0262 0.4781
Brugia malayi Calcium binding EGF domain containing protein 0.0029 0.0005 0.0006
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0187 0.0221 0.4034
Trichomonas vaginalis chromobox protein, putative 0.008 0.0075 0.0277
Echinococcus granulosus neuropeptide receptor 0.0027 0.0002 0.0001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0054 0.0038 0.0433
Loa Loa (eye worm) hypothetical protein 0.0167 0.0193 0.0285
Schistosoma mansoni Smad4 0.0034 0.0012 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0056 0.1006
Brugia malayi cytochrome P450 0.0054 0.0039 0.0055
Loa Loa (eye worm) hypothetical protein 0.0054 0.0039 0.0055
Echinococcus granulosus ferritin 0.0107 0.0112 0.0111
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0058 0.0044 0.0042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0004 0.0066
Trichomonas vaginalis D-aminoacylase, putative 0.0292 0.0365 0.1353
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0248 0.0305 0.0304
Mycobacterium ulcerans acyl-CoA synthetase 0.0054 0.0038 0.0143
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0031 0.0116
Mycobacterium leprae conserved hypothetical protein 0.0292 0.0365 0.8829
Mycobacterium ulcerans acyl-CoA synthetase 0.0054 0.0038 0.0143
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0054 0.0039 0.0136
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0441 0.0569 0.0568
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0007 0.0026
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0172 0.0201 0.0296
Chlamydia trachomatis glutamine binding protein 0.0747 0.0988 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.0038 0.0143
Brugia malayi Carboxylesterase family protein 0.0054 0.004 0.0057
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.0049 0.0183
Loa Loa (eye worm) hypothetical protein 0.0187 0.0221 0.0325
Loa Loa (eye worm) hypothetical protein 0.0032 0.0009 0.0012
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0147 0.0166 0.0165
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0017 0.0016
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0291 0.0364 0.0363
Mycobacterium leprae putative cytochrome p450 0.0054 0.0039 0.0002
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0187 0.0221 0.0219
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0054 0.0039 0.0143
Echinococcus granulosus survival motor neuron protein 1 0.1546 0.2084 0.2083
Brugia malayi glutaminase DH11.1 0.0306 0.0384 0.0567
Onchocerca volvulus 0.0058 0.0044 0.0155
Plasmodium falciparum glutathione reductase 0.0083 0.0079 0.2976
Brugia malayi K+ channel tetramerisation domain containing protein 0.0217 0.0262 0.0386
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0033 0.001 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0088 0.0327
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0054 0.0039 0.0136
Loa Loa (eye worm) hypothetical protein 0.0292 0.0365 0.0538
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.003 0.0532
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.021 0.0253 0.099
Echinococcus granulosus polycomb protein SCMH1 0.0104 0.0108 0.0107
Brugia malayi latrophilin 2 splice variant baaae 0.0437 0.0563 0.0832
Onchocerca volvulus 0.0292 0.0365 0.1346
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0043 0.0024 0.0023
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0073 0.0064 0.0062
Entamoeba histolytica acyl-CoA synthetase, putative 0.0054 0.0038 0.0433
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0044 0.0042
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Schistosoma mansoni glutaminase 0.0306 0.0384 0.0382
Trypanosoma brucei potassium voltage-gated channel, putative 0.0217 0.0262 0.7168
Brugia malayi beta-lactamase family protein 0.0292 0.0365 0.0538
Brugia malayi hypothetical protein 0.0187 0.0221 0.0325
Echinococcus granulosus solute carrier family 5 0.0043 0.0024 0.0023
Brugia malayi larval opioid receptor 0.0027 0.0002 0.0002
Schistosoma mansoni apoferritin-2 0.0107 0.0112 0.011
Brugia malayi chromobox protein homolog 3 0.0045 0.0026 0.0037
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.003 0.0006 0.0008
Brugia malayi Cytochrome P450 family protein 0.0054 0.0039 0.0055
Echinococcus multilocularis BTB:POZ domain containing protein 0.0217 0.0262 0.0261
Echinococcus granulosus sodium channel protein 0.0187 0.0221 0.022
Echinococcus granulosus allatostatin A receptor 0.0027 0.0002 0.0001
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0058 0.0044 0.0042
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.003 0.0334
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.001 0.0013

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) 0 Analgesic activity in iv dosed SHR mouse by tail clip assay ChEMBL. 16650985
ED50 (functional) = 47.4 ug/kg Analgesic activity in iv dosed SHR mouse by writhing assay ChEMBL. 16650985
ED50 (functional) = 80.3 ug/kg Analgesic activity in iv dosed SHR mouse by tail flick assay ChEMBL. 16650985
ED50 (functional) = 190.3 ug/kg Analgesic activity in iv dosed SHR mouse by hot plate assay ChEMBL. 16650985
Efficacy (functional) = 44.4 % Analgesic activity in iv dosed SHR mouse by tail clip assay ChEMBL. 16650985
Efficacy (functional) = 81 % Analgesic activity in iv dosed SHR mouse by tail flick assay ChEMBL. 16650985
Efficacy (functional) = 100 % Analgesic activity in iv dosed SHR mouse by writhing assay ChEMBL. 16650985
Efficacy (functional) = 100 % Analgesic activity in iv dosed SHR mouse by hot plate assay ChEMBL. 16650985

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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