Detailed information for compound 522722

Basic information

Technical information
  • TDR Targets ID: 522722
  • Name: N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)pro pan-2-yl]-16-pyridin-1-ium-1-ylhexadecanamide bromide
  • MW: 608.607 | Formula: C30H46BrN3O5
  • H donors: 3 H acceptors: 5 LogP: 7.68 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC[C@H]([C@@H](c1ccc(cc1)[N+](=O)[O-])O)NC(=O)CCCCCCCCCCCCCCC[n+]1ccccc1.[Br-]
  • InChi: 1S/C30H45N3O5.BrH/c34-25-28(30(36)26-18-20-27(21-19-26)33(37)38)31-29(35)17-13-10-8-6-4-2-1-3-5-7-9-11-14-22-32-23-15-12-16-24-32;/h12,15-16,18-21,23-24,28,30,34,36H,1-11,13-14,17,22,25H2;1H/t28-,30-;/m1./s1
  • InChiKey: XHPOCLVAZXCXLW-XDSAXFAGSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-16-pyridin-1-ium-1-yl-hexadecanamide bromide
  • N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-16-(1-pyridin-1-iumyl)hexadecanamide bromide
  • N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]-16-pyridin-1-ium-1-yl-hexadecanamide bromide
  • N-[(1R,2R)-2-hydroxy-1-methylol-2-(4-nitrophenyl)ethyl]-16-pyridin-1-ium-1-yl-palmitamide bromide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei sugar transporter, putative 0.0032 0.0117 0.0272
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0028 0.0087 0.0119
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.1336 0.3605
Echinococcus granulosus mitogen activated protein kinase 0.006 0.0329 0.0329
Brugia malayi major facilitator superfamily protein 0.0032 0.0117 0.016
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0029 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0127
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0056 0.0299 0.0861
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.1336 0.3605
Leishmania major oxidoreductase-like protein 0.0029 0.0093 0.025
Toxoplasma gondii oxidoreductase, putative 0.0029 0.0093 0.0197
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0025 0.0065 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0511 0.3705 1
Loa Loa (eye worm) oxidoreductase 0.0029 0.0093 0.0127
Plasmodium vivax hypothetical protein, conserved 0.0511 0.3705 0.5201
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.008 0.0473 0.1278
Echinococcus multilocularis mitogen activated protein kinase 3 0.006 0.0329 0.0329
Loa Loa (eye worm) hypothetical protein 0.007 0.0403 0.0554
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.007 0.0403 0.0858
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1414 0.3817
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0093 0.0093
Schistosoma mansoni aldehyde dehydrogenase 0.0457 0.3304 0.3304
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Trypanosoma brucei glucose transporter, putative 0.0071 0.0406 0.1056
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0428 0.3086 0.3086
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0056 0.0299 0.0861
Echinococcus multilocularis Glycoside hydrolase, family 27 0.011 0.0705 0.0705
Toxoplasma gondii melibiase subfamily protein 0.011 0.0705 0.1499
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.007 0.0403 0.0566
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0056 0.0299 0.0861
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0025 0.0065 0.0065
Loa Loa (eye worm) dehydrogenase 0.0029 0.0093 0.0127
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0511 0.3705 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0025 0.0065 0.0148
Brugia malayi Dehydrogenases, short chain protein 30 0.0029 0.0093 0.0127
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0016 0.0016
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0511 0.3705 1
Leishmania major pteridine reductase 1 0.0029 0.0093 0.025
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0025 0.0065 0.009
Brugia malayi Cam kinase protein 1 0.007 0.0403 0.0554
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0083 0.0499 0.1061
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0042 0.0188 0.0509
Echinococcus multilocularis caspase 8 0.0511 0.3705 0.3705
Mycobacterium ulcerans oxidoreductase 0.0029 0.0093 0.0232
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Leishmania major aldehyde dehydrogenase, putative 0.0025 0.0065 0.0176
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0068 0.0389 0.8771
Schistosoma mansoni inositol monophosphatase 0.0083 0.0499 0.0499
Onchocerca volvulus 0.0032 0.0117 0.016
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0068 0.0389 0.0389
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0029 0.0093 0.0207
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0093 0.025
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0511 0.3705 1
Plasmodium falciparum calcium-dependent protein kinase 4 0.007 0.0403 0.0566
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0029 0.0093 0.0232
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0065 0.0176
Mycobacterium ulcerans carveol-like dehydrogenase 0.0029 0.0093 0.0232
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0029 0.0093 0.025
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0093 0.025
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0065 0.0176
Mycobacterium leprae putative cytochrome p450 0.0056 0.0299 0.635
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0029 0.0093 0.0127
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0029 0.0093 0.0093
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0202 0.1429
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0347 0.0896
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0329 0.0889
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0029 0.0093 0.0127
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0029 0.0093 0.0093
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0025 0.0065 0.0148
Plasmodium falciparum steroid dehydrogenase, putative 0.0029 0.0093 0.013
Trypanosoma cruzi hexose transporter 0.0071 0.0406 0.1095
Schistosoma mansoni carbonyl reductase 0.0029 0.0093 0.0093
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.007 0.0403 0.0554
Onchocerca volvulus 0.0029 0.0093 0.0127
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0232 0.0326
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0029 0.0093 0.0745
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0083 0.0499 0.1469
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Echinococcus granulosus hypothetical protein 0.0029 0.0093 0.0093
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0347 0.0936
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0029 0.0093 0.0745
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0188 0.0509
Schistosoma mansoni hypothetical protein 0.0228 0.1583 0.1583
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Echinococcus granulosus steroid dehydrogenase 0.0029 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0074 0.0434 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0428 0.3086 0.9338
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Plasmodium vivax steroid dehydrogenase, putative 0.0029 0.0093 0.013
Toxoplasma gondii protein kinase, putative 0.0644 0.4703 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Toxoplasma gondii transporter, major facilitator family protein 0.0032 0.0117 0.0248
Schistosoma mansoni ap endonuclease 0.0019 0.0016 0.0016
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.011 0.0705 0.0705
Giardia lamblia Lysyl-tRNA synthetase 0.0051 0.0258 0.1852
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0347 0.0896
Entamoeba histolytica hypothetical protein 0.0029 0.0093 0.0702
Trypanosoma brucei protein kinase, putative 0.006 0.0329 0.0848
Brugia malayi PAS domain containing protein 0.016 0.1077 0.1481
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.007 0.0403 0.0403
Schistosoma mansoni hypothetical protein 0.0476 0.3443 0.3443
Brugia malayi Cytochrome P450 family protein 0.0095 0.059 0.0812
Entamoeba histolytica protein kinase, putative 0.007 0.0403 0.3056
Loa Loa (eye worm) hypothetical protein 0.0074 0.0429 0.059
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0093 0.025
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0029 0.0093 0.0232
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Trypanosoma brucei glucose transporter 2A 0.0071 0.0406 0.1056
Loa Loa (eye worm) hypothetical protein 0.0068 0.0389 0.0534
Schistosoma mansoni glucose transport protein 0.0228 0.1583 0.1583
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.007 0.0403 0.0403
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0056 0.0299 0.0808
Trypanosoma brucei short-chain dehydrogenase, putative 0.0029 0.0093 0.0207
Plasmodium vivax proline--tRNA ligase, putative 0.008 0.0473 0.0665
Schistosoma mansoni protein kinase 0.007 0.0403 0.0403
Echinococcus granulosus WW domain containing oxidoreductase 0.0029 0.0093 0.0093
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0065 0.0065
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0511 0.3705 1
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0056 0.0299 0.0861
Trypanosoma brucei glucose transporter, putative 0.0071 0.0406 0.1056
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0093 0.025
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0029 0.0093 0.025
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0745
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0025 0.0065 0.0065
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0025 0.0065 0.0176
Plasmodium falciparum metacaspase 1 0.0511 0.3705 0.5201
Trypanosoma cruzi metacaspase, putative 0.0511 0.3705 1
Onchocerca volvulus Putative transporter 0.0032 0.0117 0.016
Echinococcus multilocularis caspase 0.135 1 1
Echinococcus multilocularis caspase 2 0.0986 0.7271 0.7271
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Trypanosoma cruzi metacaspase, putative 0.0511 0.3705 1
Onchocerca volvulus 0.0029 0.0093 0.0127
Loa Loa (eye worm) oxidoreductase 0.0029 0.0093 0.0127
Echinococcus multilocularis conserved hypothetical protein 0.0029 0.0093 0.0093
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0029 0.0093 0.025
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0117 0.0315
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0228 0.1583 0.1583
Echinococcus granulosus apoptotic protease activating factor 1 0.0476 0.3443 0.3443
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0093 0.025
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.006 0.0329 0.0848
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Leishmania major aldehyde dehydrogenase, putative 0.0025 0.0065 0.0176
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0025 0.0065 0.0176
Schistosoma mansoni sugar transporter 0.0032 0.0117 0.0117
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0029 0.0093 0.013
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0192 0.1319 0.1319
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0029 0.0093 0.0197
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0043 0.02 0.0559
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0117 0.0315
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0093 0.0232
Brugia malayi major facilitator superfamily protein 0.0032 0.0117 0.016
Onchocerca volvulus 0.0032 0.0117 0.016
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0192 0.1319 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0457 0.3304 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.008 0.0473 0.1278
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.007 0.0403 0.0566
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0042 0.0188 0.0259
Brugia malayi bHLH-PAS transcription factor 0.0118 0.0765 0.1052
Trypanosoma cruzi short chain dehydrogenase, putative 0.0029 0.0093 0.025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0457 0.3304 1
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0032 0.0117 0.2075
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0046 0.0225 0.0607
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0042 0.0188 0.6549
Leishmania major glucose transporter, lmgt2 0.0071 0.0406 0.1095
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0093 0.025
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0117 0.0315
Mycobacterium ulcerans aldehyde dehydrogenase 0.0457 0.3304 1
Loa Loa (eye worm) major facilitator superfamily transporter 0.0032 0.0117 0.016
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0029 0.0093 0.0232
Mycobacterium ulcerans putative regulatory protein 0.0118 0.0765 0.2277
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.007 0.0403 0.1048
Trypanosoma brucei short-chain dehydrogenase, putative 0.0029 0.0093 0.0207
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0093 0.025
Schistosoma mansoni serine/threonine protein kinase 0.007 0.0403 0.0403
Echinococcus multilocularis steroid dehydrogenase 0.0029 0.0093 0.0093
Loa Loa (eye worm) oxidoreductase 0.0029 0.0093 0.0127
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Trypanosoma brucei oxidoreductase-like protein 0.0029 0.0093 0.0207
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0093 0.0093
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0056 0.0299 0.0861
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0056 0.0299 0.0861
Mycobacterium ulcerans short-chain dehydrogenase 0.0029 0.0093 0.0232
Leishmania major hypothetical protein, conserved 0.0029 0.0093 0.025
Schistosoma mansoni caspase-7 (C14 family) 0.0986 0.7271 0.7271
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0127
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0511 0.3705 0.3705
Loa Loa (eye worm) oxidoreductase 0.0029 0.0093 0.0127
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0025 0.0065 0.0148
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.006 0.0329 0.0889
Echinococcus multilocularis retinol dehydrogenase 11 0.0029 0.0093 0.0093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0347 0.0896
Echinococcus multilocularis synaptic vesicle 2 protein 0.0032 0.0117 0.0117
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0329 0.0889
Brugia malayi oxidoreductase 0.0029 0.0093 0.0127
Trypanosoma cruzi metacaspase, putative 0.0511 0.3705 1
Echinococcus multilocularis transfer RNA-Lys 0.0118 0.0765 0.0765
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1414 0.3817
Giardia lamblia Hypothetical protein 0.0029 0.0093 0.0586
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.006 0.0329 0.07
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.007 0.0403 0.0858
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0025 0.0065 0.0176
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0202 0.1535
Giardia lamblia Prolyl-tRNA synthetase 0.0068 0.0389 0.2858
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0083 0.0499 0.1347
Mycobacterium ulcerans ketoacyl reductase 0.0029 0.0093 0.0232
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0065 0.0176
Loa Loa (eye worm) hypothetical protein 0.0025 0.0065 0.009
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0511 0.3705 1
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0065 0.0065
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.007 0.0403 0.0554
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0192 0.1319 0.353
Trichomonas vaginalis adenylate cyclase, putative 0.0042 0.0188 0.0509
Brugia malayi Cytochrome P450 family protein 0.0056 0.0299 0.0412
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0457 0.3304 0.8916
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0329 0.0329
Leishmania major metacaspase, putative 0.0511 0.3705 1
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0056 0.0299 0.0861
Schistosoma mansoni sugar transporter 0.0032 0.0117 0.0117
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0025 0.0065 0.0176
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0399 0.287 0.3947
Onchocerca volvulus 0.0029 0.0093 0.0127
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0056 0.0299 0.0861
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0297 0.2101 0.2889
Echinococcus multilocularis steroid dehydrogenase 0.0029 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0127
Onchocerca volvulus 0.0032 0.0117 0.016
Schistosoma mansoni glucose transport protein 0.0228 0.1583 0.1583
Loa Loa (eye worm) oxidoreductase 0.0029 0.0093 0.0127
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0093 0.013
Brugia malayi Retinol dehydrogenase 12 0.0029 0.0093 0.0127
Brugia malayi hypothetical protein 0.0476 0.3443 0.4734
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0029 0.0093 0.0207
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0511 0.3705 0.788
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0228 0.1583 0.1583
Trypanosoma cruzi hexose transporter, putative 0.0039 0.0166 0.0448
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0093 0.0232
Echinococcus multilocularis aryl hydrocarbon receptor 0.0042 0.0188 0.0188
Brugia malayi MAP kinase sur-1 0.006 0.0329 0.0453
Trypanosoma cruzi sugar transporter, putative 0.0032 0.0117 0.0315
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0029 0.0093 0.0093
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0025 0.0065 0.0148
Plasmodium falciparum hexose transporter 0.0228 0.1583 0.2222
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0117 0.0315
Loa Loa (eye worm) hypothetical protein 0.0055 0.0293 0.0402
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0029 0.0093 0.0232
Schistosoma mansoni sugar transporter 0.0032 0.0117 0.0117
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0025 0.0065 0.009
Entamoeba histolytica hypothetical protein, conserved 0.0029 0.0093 0.0702
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0068 0.0389 0.1049
Leishmania major glucose transporter/membrane transporter D2, putative 0.0071 0.0406 0.1095
Brugia malayi Cell death protein 3 precursor 0.0986 0.7271 1
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0025 0.0065 0.0494
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0056 0.0299 0.0861
Schistosoma mansoni lysyl-tRNA synthetase 0.0051 0.0258 0.0258
Trypanosoma brucei Metacaspase-4 0.0511 0.3705 1
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0025 0.0065 0.0132
Treponema pallidum prolyl-tRNA synthetase 0.0024 0.0057 0.8417
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0025 0.0065 0.0139
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0016 0.0023
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0016 0.0044
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Trypanosoma brucei glucose transporter, putative 0.0071 0.0406 0.1056
Trypanosoma brucei metacaspase 0.0511 0.3705 1
Trypanosoma brucei glucose transporter, putative 0.0071 0.0406 0.1056
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0029 0.0093 0.025
Brugia malayi Aldehyde dehydrogenase protein 4 0.0025 0.0065 0.009
Plasmodium falciparum calcium-dependent protein kinase 5 0.007 0.0403 0.0566
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Loa Loa (eye worm) major facilitator superfamily transporter 0.0032 0.0117 0.016
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0029 0.0093 0.0702
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Onchocerca volvulus 0.0029 0.0093 0.0127
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.006 0.0329 0.0889
Schistosoma mansoni protein kinase 0.007 0.0403 0.0403
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0051 0.0258 0.5217
Plasmodium falciparum metacaspase-like protein 0.0511 0.3705 0.5201
Onchocerca volvulus 0.0032 0.0117 0.016
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0056 0.0299 0.0861
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0297 0.2101 0.2889
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0428 0.3086 0.3086
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0745
Echinococcus multilocularis oxidoreductase 0.0029 0.0093 0.0093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0347 0.0896
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.006 0.0329 0.0889
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0197
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.011 0.0705 0.0705
Mycobacterium leprae Probable oxidoreductase 0.0029 0.0093 0.0745
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Wolbachia endosymbiont of Brugia malayi bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 0.0025 0.0065 0.101
Trypanosoma cruzi hexose transporter, putative 0.0071 0.0406 0.1095
Echinococcus granulosus caspase 2 0.0986 0.7271 0.7271
Loa Loa (eye worm) oxidoreductase 0.0029 0.0093 0.0127
Schistosoma mansoni ap endonuclease 0.0019 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0056 0.0299 0.0808
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0074 0.0429 0.1157
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0127
Toxoplasma gondii exonuclease III APE 0.0019 0.0016 0.0035
Echinococcus granulosus single minded 2 0.0118 0.0765 0.0765
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0056 0.0299 0.0861
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0029 0.0093 0.0586
Echinococcus granulosus cytochrome P450 2K1 0.0056 0.0299 0.0299
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0065 0.0176
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0029 0.0093 0.025
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0029 0.0093 0.025
Plasmodium falciparum lysine--tRNA ligase 0.0051 0.0258 0.0361
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0025 0.0065 0.0176
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0192 0.1319 1
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0511 0.3705 0.5096
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0029 0.0093 0.0197
Echinococcus granulosus carbonyl reductase 1 0.0029 0.0093 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.2101 0.5669
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.008 0.0473 0.1239
Echinococcus granulosus retinol dehydrogenase 11 0.0029 0.0093 0.0093
Trypanosoma brucei metacaspase 5, putative 0.0511 0.3705 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0025 0.0065 0.0065
Trypanosoma cruzi cytochrome P450, putative 0.0066 0.0371 0.1002
Plasmodium falciparum calcium-dependent protein kinase 1 0.007 0.0403 0.0566
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0042 0.0188 0.0509
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0428 0.3086 0.9338
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0029 0.0093 0.0232
Toxoplasma gondii lysine-tRNA ligase 0.0051 0.0258 0.0548
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0093 0.025
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0032 0.0117 0.0305
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0368 0.2638 0.3703
Trichomonas vaginalis conserved hypothetical protein 0.0228 0.1583 0.4273
Mycobacterium tuberculosis Possible oxidoreductase 0.0029 0.0093 0.0232
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0029 0.0093 0.0093
Onchocerca volvulus 0.0032 0.0117 0.016
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0016 0.0023
Onchocerca volvulus 0.0029 0.0093 0.0127
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0074 0.0429 0.0429
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0232 0.0232
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Echinococcus granulosus carbonyl reductase 1 0.0029 0.0093 0.0093
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0024 0.0057 0.0125
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0202 0.0284
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.1336 0.3605
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0042 0.0188 0.0509
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0368 0.2638 0.561
Mycobacterium ulcerans dehydrogenase 0.0029 0.0093 0.0232
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0228 0.1583 0.1583
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0347 0.0896
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0051 0.0258 0.0695
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0117 0.0315
Mycobacterium leprae Conserved hypothetical protein 0.0056 0.0299 0.635
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0056 0.0299 0.0808
Loa Loa (eye worm) oxidoreductase 0.0029 0.0093 0.0127
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0025 0.0065 0.0132
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0065 0.0065
Leishmania major hypothetical protein, conserved 0.0029 0.0093 0.025
Brugia malayi Sugar transporter family protein 0.0228 0.1583 0.2177
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0074 0.0429 0.0429
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0056 0.0299 0.0861
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0127
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Echinococcus granulosus calcium dependent protein kinase 0.0065 0.0367 0.0367
Onchocerca volvulus 0.0032 0.0117 0.016
Loa Loa (eye worm) hypoxia-induced factor 1 0.0495 0.3591 0.4938
Mycobacterium ulcerans aldehyde dehydrogenase 0.0025 0.0065 0.0148
Brugia malayi dehydrogenases, short chain protein 9 0.0029 0.0093 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0511 0.3705 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Onchocerca volvulus 0.0029 0.0093 0.0127
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0347 0.0936
Trypanosoma cruzi glucose transporter, putative 0.0032 0.0117 0.0315
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0029 0.0093 0.0207
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0511 0.3705 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Onchocerca volvulus 0.0032 0.0117 0.016
Schistosoma mansoni single-minded 0.016 0.1077 0.1077
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0329 0.0889
Echinococcus multilocularis solute carrier family 22 0.0032 0.0117 0.0117
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0083 0.0499 0.1347
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0093 0.025
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Schistosoma mansoni aldehyde dehydrogenase 0.0457 0.3304 0.3304
Trypanosoma brucei metacaspase MCA2 0.0511 0.3705 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0068 0.0389 0.0389
Echinococcus granulosus carbonyl reductase 1 0.0029 0.0093 0.0093
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0025 0.0065 0.0139
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0093 0.0093
Trypanosoma brucei metacaspase MCA3 0.0511 0.3705 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0192 0.1319 0.1319
Trypanosoma brucei glucose transporter, putative 0.0071 0.0406 0.1056
Brugia malayi hypothetical protein 0.0029 0.0093 0.0127
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0025 0.0065 0.0148
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0025 0.0065 0.0065
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0056 0.0299 0.0861
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0093 0.0232
Echinococcus granulosus histone acetyltransferase KAT2B 0.0157 0.1051 0.1051
Onchocerca volvulus 0.0032 0.0117 0.016
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0029 0.0093 0.025
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.1336 0.3605
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0046 0.0225 0.0607
Onchocerca volvulus 0.0029 0.0093 0.0127
Brugia malayi hypothetical protein 0.0032 0.0117 0.016
Schistosoma mansoni carbonyl reductase 0.0029 0.0093 0.0093
Trichomonas vaginalis inositol monophosphatase, putative 0.0083 0.0499 0.1347
Loa Loa (eye worm) hypothetical protein 0.0068 0.0389 0.0534
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0093 0.0093
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0029 0.0093 0.0702
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0127
Schistosoma mansoni glucose transporter 0.0032 0.0117 0.0117
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0029 0.0093 0.0232
Mycobacterium tuberculosis Probable dehydrogenase 0.0029 0.0093 0.0232
Onchocerca volvulus 0.0032 0.0117 0.016
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0127
Loa Loa (eye worm) oxidoreductase 0.0029 0.0093 0.0127
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0093 0.025
Giardia lamblia Reductase, putative 0.0029 0.0093 0.0586
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.006 0.0329 0.0889
Echinococcus multilocularis 0.0056 0.0299 0.0299
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0029 0.0093 0.0093
Echinococcus granulosus caspase 0.135 1 1
Mycobacterium ulcerans ketoacyl reductase 0.0029 0.0093 0.0232
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0029 0.0093 0.0127
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0025 0.0065 0.0148
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0042 0.0188 0.0509
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0117 0.0315
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0117 0.0315
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0511 0.3705 0.788
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Leishmania major aldehyde dehydrogenase, putative 0.0025 0.0065 0.0176
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.008 0.0473 0.1278
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0042 0.0188 0.0509
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Plasmodium falciparum calcium-dependent protein kinase 2 0.007 0.0403 0.0566
Schistosoma mansoni hypothetical protein 0.0056 0.0299 0.0299
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0025 0.0065 0.0176
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Onchocerca volvulus 0.0029 0.0093 0.0127
Trypanosoma brucei glucose transporter 1E 0.0071 0.0406 0.1056
Echinococcus multilocularis transient receptor potential cation channel 0.0029 0.0093 0.0093
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0029 0.0093 0.0207
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0029 0.0093 0.0127
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0066 0.0371 0.108
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0025 0.0065 0.0176
Loa Loa (eye worm) hypothetical protein 0.0537 0.3903 0.5367
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0161 0.1085 0.1085
Schistosoma mansoni cytochrome P450 0.0056 0.0299 0.0299
Plasmodium vivax metacaspase 1, putative 0.0511 0.3705 0.5201
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0428 0.3086 0.4244
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0016 0.0044
Echinococcus granulosus solute carrier family 22 0.0032 0.0117 0.0117
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0029 0.0093 0.0232
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0029 0.0093 0.0232
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0093 0.0093
Echinococcus granulosus lysyl tRNA synthetase 0.0051 0.0258 0.0258
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.2101 0.5669
Loa Loa (eye worm) cytochrome P450 family protein 0.0066 0.0371 0.0511
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Trichomonas vaginalis sugar transport protein, putative 0.0032 0.0117 0.0315
Brugia malayi hypothetical protein 0.0029 0.0093 0.0127
Trichomonas vaginalis glucose transporter, putative 0.0071 0.0406 0.1095
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Brugia malayi Dehydrogenases, short chain protein 2 0.0029 0.0093 0.0127
Brugia malayi hypothetical protein 0.0032 0.0117 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0511 0.3705 1
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0093 0.025
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0192 0.1319 0.1319
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0029 0.0093 0.025
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0347 0.0936
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0093 0.0093
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0192 0.1319 0.3558
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0056 0.0299 0.0861
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0056 0.0299 0.0861
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0025 0.0065 0.0148
Trypanosoma brucei short-chain dehydrogenase, putative 0.0029 0.0093 0.0207
Brugia malayi cytochrome P450 0.0056 0.0299 0.0412
Entamoeba histolytica short chain dehydrogenase family protein 0.0029 0.0093 0.0702
Echinococcus multilocularis retinol dehydrogenase 11 0.0029 0.0093 0.0093
Leishmania major cathepsin L-like protease 0.0063 0.0347 0.0936
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0068 0.0389 0.2947
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0032 0.0117 0.0305
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0025 0.0065 0.009
Schistosoma mansoni hypothetical protein 0.0025 0.0065 0.0065
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Trypanosoma brucei THT1 - hexose transporter, putative 0.0071 0.0406 0.1056
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0068 0.0389 0.0389
Echinococcus multilocularis General substrate transporter 0.0196 0.1343 0.1343
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0074 0.0434 0.127
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0032 0.0117 0.0117
Echinococcus granulosus solute carrier family 22 0.0032 0.0117 0.0117
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0042 0.0188 0.0509
Loa Loa (eye worm) hypothetical protein 0.0051 0.0258 0.0354
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Brugia malayi Sugar transporter family protein 0.0032 0.0117 0.016
Loa Loa (eye worm) CYP4Cod1 0.0066 0.0371 0.0511
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0029 0.0093 0.0093
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Brugia malayi Melibiase family protein 0.0074 0.0429 0.059
Brugia malayi follicle stimulating hormone receptor 0.0493 0.3569 0.4908
Trichomonas vaginalis sugar transporter, putative 0.0071 0.0406 0.1095
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0192 0.1319 0.1319
Loa Loa (eye worm) acetyltransferase 0.0161 0.1085 0.1493
Loa Loa (eye worm) sugar transporter 0.0032 0.0117 0.016
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0029 0.0093 0.025
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0029 0.0093 0.1579
Toxoplasma gondii sugar transporter ST2 0.0032 0.0117 0.0248
Trypanosoma cruzi metacaspase, putative 0.0511 0.3705 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0347 0.0896
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0228 0.1583 0.1583
Schistosoma mansoni retinal dehydrogenase 0.0029 0.0093 0.0093
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0511 0.3705 0.5096
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0083 0.0499 0.1347
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0029 0.0093 0.0232
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0029 0.0093 0.025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0347 0.0896
Trichomonas vaginalis glucose transporter, putative 0.0071 0.0406 0.1095
Echinococcus multilocularis calcium dependent protein kinase 0.0065 0.0367 0.0367
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0025 0.0065 0.0139
Onchocerca volvulus 0.0032 0.0117 0.016
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0232 0.0493
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0025 0.0065 0.0148
Brugia malayi Major Facilitator Superfamily protein 0.0032 0.0117 0.016
Entamoeba histolytica protein kinase, putative 0.007 0.0403 0.3056
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0192 0.1319 0.1319
Plasmodium falciparum calcium-dependent protein kinase 3 0.007 0.0403 0.0566
Echinococcus granulosus solute carrier family 22 0.0032 0.0117 0.0117
Giardia lamblia Kinase, CMGC MAPK 0.006 0.0329 0.2403
Echinococcus granulosus aryl hydrocarbon receptor 0.0042 0.0188 0.0188
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0065 0.0065
Echinococcus multilocularis lysyl tRNA synthetase 0.0051 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0192 0.1319 0.1813
Onchocerca volvulus Glucosylceramidase homolog 0.0195 0.1336 0.1837
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0042 0.0188 0.0509
Trypanosoma brucei short-chain dehydrogenase, putative 0.0029 0.0093 0.0207
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0016 0.0016
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0192 0.1319 0.3558
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0228 0.1583 0.1583
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0029 0.0093 0.025
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0228 0.1583 0.1583
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0192 0.1319 0.1319
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Onchocerca volvulus 0.0032 0.0117 0.016
Toxoplasma gondii oxidoreductase, putative 0.0029 0.0093 0.0197
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0025 0.0065 0.0148
Plasmodium vivax lysine--tRNA ligase, putative 0.0051 0.0258 0.0361
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0025 0.0065 0.0148
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.2101 0.5669
Leishmania major hypothetical protein, conserved 0.0029 0.0093 0.025
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0056 0.0299 0.0861
Onchocerca volvulus 0.0032 0.0117 0.016
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Plasmodium vivax hexose transporter 0.0228 0.1583 0.2222
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0347 0.0896
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0093 0.025
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0025 0.0065 0.0132
Brugia malayi acetyltransferase, GNAT family protein 0.0161 0.1085 0.1493
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0161 0.1085 0.1085
Trypanosoma brucei glucose transporter, putative 0.0071 0.0406 0.1056
Onchocerca volvulus 0.0042 0.0188 0.0259
Plasmodium falciparum proline--tRNA ligase 0.008 0.0473 0.0665
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0046 0.0225 0.0607
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0025 0.0065 0.009
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0428 0.3086 0.9338
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.007 0.0403 0.0858
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Onchocerca volvulus 0.0032 0.0117 0.016
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0032 0.0117 0.0117
Leishmania major hypothetical protein, conserved 0.0032 0.0117 0.0315
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Echinococcus granulosus synaptic vesicle 2 protein 0.0032 0.0117 0.0117
Trypanosoma cruzi short chain dehydrogenase, putative 0.0029 0.0093 0.025
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0016 0.0044
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0197
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0306 0.0826
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0232 0.0493
Trypanosoma cruzi metacaspase 5, putative 0.0511 0.3705 1
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0025 0.0065 0.0132
Onchocerca volvulus 0.0029 0.0093 0.0127
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0056 0.0299 0.0861
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0029 0.0093 0.013
Echinococcus granulosus solute carrier family 22 0.0032 0.0117 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0188 0.0509
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0029 0.0093 0.0232
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0025 0.0065 0.0176
Toxoplasma gondii carbonyl reductase 1, putative 0.0029 0.0093 0.0197
Leishmania major protein kinase, putative 0.0046 0.0225 0.0607
Onchocerca volvulus 0.0032 0.0117 0.016
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0056 0.0299 0.0861
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Echinococcus granulosus mitogen activated protein kinase 3 0.006 0.0329 0.0329
Trypanosoma cruzi metacaspase 5, putative 0.0511 0.3705 1
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0329 0.0889
Onchocerca volvulus 0.0476 0.3443 0.4734
Onchocerca volvulus Cell death protein 3 homolog 0.0986 0.7271 1
Trichomonas vaginalis conserved hypothetical protein 0.0511 0.3705 1
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Brugia malayi dehydrogenases, short chain protein 2 0.0029 0.0093 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0406 0.1095
Leishmania major dehydrogenase-like protein 0.0029 0.0093 0.025
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0043 0.02 0.0559
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0056 0.0299 0.0861
Entamoeba histolytica short chain dehydrogenase family protein 0.0029 0.0093 0.0702
Onchocerca volvulus 0.0032 0.0117 0.016
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.007 0.0403 0.0403
Schistosoma mansoni lysyl-tRNA synthetase 0.0051 0.0258 0.0258
Plasmodium vivax CDK-related protein kinase 6, putative 0.0967 0.7124 1
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0056 0.0299 0.0861
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0093 0.025
Echinococcus granulosus hypothetical protein 0.0029 0.0093 0.0093
Toxoplasma gondii sugar transporter ST3 0.0032 0.0117 0.0248
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0025 0.0065 0.0148
Echinococcus multilocularis carbonyl reductase 1 0.0029 0.0093 0.0093
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0403 0.1088
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0083 0.0499 0.1347
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0042 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Trypanosoma brucei THT1 - hexose transporter, putative 0.0071 0.0406 0.1056
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Leishmania major cytochrome p450-like protein 0.0066 0.0371 0.1002
Schistosoma mansoni sugar transporter 0.0032 0.0117 0.0117
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0511 0.3705 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0056 0.0299 0.0861
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0025 0.0065 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0192 0.1319 0.3558
Echinococcus multilocularis caspase 3 0.084 0.6171 0.6171
Leishmania major lysyl-tRNA synthetase, putative 0.0051 0.0258 0.0695
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0029 0.0093 0.0702
Schistosoma mansoni glucose transport protein 0.0228 0.1583 0.1583
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0025 0.0065 0.0065
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0025 0.0065 0.0065
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0032 0.0117 0.0272
Loa Loa (eye worm) hypothetical protein 0.0025 0.0065 0.009
Entamoeba histolytica hypothetical protein, conserved 0.0029 0.0093 0.0702
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0493 0.3569 0.4908
Brugia malayi hypothetical protein 0.0032 0.0117 0.016
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0056 0.0299 0.0861
Chlamydia trachomatis lysine--tRNA ligase 0.0051 0.0258 1
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0051 0.0258 0.0654
Schistosoma mansoni protein kinase 0.007 0.0403 0.0403
Echinococcus granulosus caspase 3 0.084 0.6171 0.6171
Echinococcus multilocularis apoptotic protease activating factor 1 0.0476 0.3443 0.3443
Loa Loa (eye worm) aldehyde dehydrogenase 0.0025 0.0065 0.009
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0329 0.0889
Echinococcus multilocularis retinol dehydrogenase 13 0.0029 0.0093 0.0093
Echinococcus granulosus Sugar transporter ERD6 protein 0.0032 0.0117 0.0117
Schistosoma mansoni aryl hydrocarbon receptor 0.016 0.1077 0.1077
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0032 0.0117 0.0305
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0246 0.0664
Leishmania major cathepsin L-like protease 0.0063 0.0347 0.0936
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0025 0.0065 0.0065
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0029 0.0093 0.0232
Echinococcus granulosus General substrate transporter 0.0196 0.1343 0.1343
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0127
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.007 0.0403 0.0554
Schistosoma mansoni inositol monophosphatase 0.0083 0.0499 0.0499
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0232 0.0626
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0093 0.025
Loa Loa (eye worm) cytochrome P450 family protein 0.0066 0.0371 0.0511
Onchocerca volvulus 0.0029 0.0093 0.0127
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0093 0.025
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Toxoplasma gondii facilitative glucose transporter GT1 0.0228 0.1583 0.3367
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0025 0.0065 0.0176
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0025 0.0065 0.0148
Giardia lamblia Short-chain dehydrogenase, putative 0.0029 0.0093 0.0586
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.007 0.0403 0.0566
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0029 0.0093 0.0702
Trypanosoma cruzi cytochrome P450, putative 0.0066 0.0371 0.1002
Trichomonas vaginalis conserved hypothetical protein 0.0511 0.3705 1
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0025 0.0065 0.0494
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Brugia malayi hypothetical protein 0.0537 0.3903 0.5367
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0025 0.0065 0.0494
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.1336 0.3605
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0029 0.0093 0.025
Echinococcus multilocularis solute carrier family 22 0.0032 0.0117 0.0117
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0228 0.1583 0.1583
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0056 0.0299 0.0808
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0056 0.0299 0.0861
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0056 0.0299 0.0861
Trypanosoma brucei cytochrome P450, putative 0.0066 0.0371 0.0962
Leishmania major short chain dehydrogenase-like protein 0.0029 0.0093 0.025
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0056 0.0299 0.0861
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0406 0.1095
Treponema pallidum gamma-glutamyl phosphate reductase 0.0025 0.0065 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0083 0.0499 0.1309
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0029 0.0093 0.025
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Onchocerca volvulus Sepiapterin reductase homolog 0.0029 0.0093 0.0127
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0051 0.0258 0.0695
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0056 0.0299 0.0861
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.2101 0.5669
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0232 0.0626
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0056 0.0299 0.0861
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Brugia malayi Major Facilitator Superfamily protein 0.0032 0.0117 0.016
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0228 0.1583 0.1583
Leishmania major short chain dehydrogenase/reductase, putative 0.0029 0.0093 0.025
Onchocerca volvulus 0.0029 0.0093 0.0127
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0093 0.0232
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Loa Loa (eye worm) sugar transporter 0.0228 0.1583 0.2177
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0428 0.3086 0.8329
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0029 0.0093 0.025
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0025 0.0065 0.0148
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0093 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.1336 0.3605
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0025 0.0065 0.0139
Leishmania major short chain dehydrogenase, putative 0.0029 0.0093 0.025
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0029 0.0093 0.0232
Schistosoma mansoni peptidase 0.002 0.0029 0.0029
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.007 0.0403 0.0403
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0029 0.0093 0.0232
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.007 0.0403 0.0403
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0056 0.0299 0.0861
Leishmania major myo-inositol/proton symporter (MIT) 0.0032 0.0117 0.0315
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.007 0.0403 0.0403
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0025 0.0065 0.0065
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0029 0.0093 0.025
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0056 0.0299 0.0861
Trypanosoma brucei glucose transporter, putative 0.0071 0.0406 0.1056
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0029 0.0093 0.0232
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0511 0.3705 1
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0029 0.0093 0.025
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0083 0.0499 0.1347
Schistosoma mansoni caspase-3 (C14 family) 0.135 1 1
Giardia lamblia Sugar-proton symporter 0.0032 0.0117 0.0769
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0051 0.0258 0.0734
Leishmania major protein kinase, putative 0.0046 0.0225 0.0607
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.007 0.0403 0.0403
Plasmodium falciparum protein kinase 6 0.0967 0.7124 1
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0347 0.0936
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Leishmania major protein kinase, putative 0.007 0.0403 0.1088
Brugia malayi Sugar transporter family protein 0.0032 0.0117 0.016
Plasmodium falciparum protein kinase 7 0.0644 0.4703 0.6601
Echinococcus multilocularis carbonyl reductase 1 0.0029 0.0093 0.0093
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0016 0.0023
Echinococcus multilocularis mitogen activated protein kinase 0.006 0.0329 0.0329
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0083 0.0499 0.3786
Brugia malayi Cytochrome P450 family protein 0.0066 0.0371 0.0511
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0056 0.0299 0.0861
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0029 0.0093 0.0093
Schistosoma mansoni aldehyde dehydrogenase 0.0025 0.0065 0.0065
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0457 0.3304 0.3304
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0025 0.0065 0.0148
Echinococcus granulosus retinol dehydrogenase 11 0.0029 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0127
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Trichomonas vaginalis guanylate cyclase, putative 0.0042 0.0188 0.0509
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0192 0.1319 0.1319
Giardia lamblia Hexose transporter 0.0032 0.0117 0.0769
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0025 0.0065 0.0494
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0197
Schistosoma mansoni short chain dehydrogenase 0.0029 0.0093 0.0093
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0025 0.0065 0.0148
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0029 0.0093 0.025
Loa Loa (eye worm) hypothetical protein 0.0042 0.0188 0.0259
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.006 0.0329 0.0453
Onchocerca volvulus 0.0118 0.0765 0.1052
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0016 0.0044
Leishmania major cytochrome p450-like protein 0.0056 0.0299 0.0808
Leishmania major glucose transporter, lmgt3 0.0071 0.0406 0.1095
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0093 0.025
Leishmania major glucose transporter, lmgt1 0.0071 0.0406 0.1095
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0043 0.02 0.366
Trichomonas vaginalis guanylate cyclase, putative 0.0042 0.0188 0.0509
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0029 0.0093 0.0197
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0046 0.0225 0.0607
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0093 0.025
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0056 0.0299 0.0861
Trypanosoma cruzi hexose transporter, putative 0.0071 0.0406 0.1095
Mycobacterium ulcerans short-chain dehydrogenase 0.0029 0.0093 0.0232
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0029 0.0093 0.0232
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0068 0.0389 0.0389
Onchocerca volvulus 0.0029 0.0093 0.0127
Echinococcus multilocularis inositol monophosphatase 1 0.0083 0.0499 0.0499
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.011 0.0705 0.0705
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0025 0.0065 0.0148
Echinococcus multilocularis carbonyl reductase 1 0.0029 0.0093 0.0093
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0083 0.0499 1
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0032 0.0117 0.0164
Leishmania major cathepsin L-like protease 0.0063 0.0347 0.0936
Mycobacterium ulcerans dehydrogenase/reductase 0.0029 0.0093 0.0232
Plasmodium falciparum mitogen-activated protein kinase 2 0.0368 0.2638 0.3703
Mycobacterium ulcerans short-chain type oxidoreductase 0.0029 0.0093 0.0232
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0029 0.0093 0.0093
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0029 0.0093 0.025
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0025 0.0065 0.0065
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.2101 0.5669
Trypanosoma brucei THT1 - hexose transporter, putative 0.0071 0.0406 0.1056
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0093 0.0232
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Trypanosoma cruzi hexose transporter, putative 0.0071 0.0406 0.1095
Brugia malayi Inositol-1 0.0083 0.0499 0.0686
Loa Loa (eye worm) dehydrogenase 0.0029 0.0093 0.0127
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0016 0.0023
Loa Loa (eye worm) hypothetical protein 0.0476 0.3443 0.4734
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0127
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0025 0.0065 0.0148
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0029 0.0093 0.0127
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0025 0.0065 0.009
Echinococcus granulosus ubiquitin specific protease 41 0.0192 0.1319 0.1319
Mycobacterium leprae Possible regulatory protein 0.0042 0.0188 0.3344
Entamoeba histolytica hypothetical protein 0.0051 0.0258 0.1953
Mycobacterium tuberculosis Possible oxidoreductase 0.0029 0.0093 0.0232
Plasmodium vivax calcium-dependent protein kinase, putative 0.007 0.0403 0.0566
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0093 0.0093
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0329 0.0889
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.008 0.0473 0.1007
Toxoplasma gondii cytochrome p450 superfamily protein 0.0056 0.0299 0.0637
Loa Loa (eye worm) oxidoreductase 0.0029 0.0093 0.0127
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.008 0.0473 0.1278
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0192 0.1319 0.3558
Trichomonas vaginalis steroid dehydrogenase, putative 0.0029 0.0093 0.025
Leishmania major short chain dehydrogenase, putative 0.0029 0.0093 0.025
Leishmania major hypothetical protein, conserved 0.0029 0.0093 0.025
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Loa Loa (eye worm) cytochrome P450 family protein 0.0095 0.059 0.0812
Echinococcus granulosus caspase 8 0.0511 0.3705 0.3705
Brugia malayi aldehyde dehydrogenase 0.0025 0.0065 0.009
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0093 0.0232
Schistosoma mansoni carbonyl reductase 0.0029 0.0093 0.0093
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.011 0.0705 0.0705
Echinococcus granulosus oxidoreductase 0.0029 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0986 0.7271 1
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0029 0.0093 0.0702
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.2101 0.5669
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.135 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0347 0.0896
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0197
Schistosoma mansoni steroid dehydrogenase 0.0029 0.0093 0.0093
Echinococcus granulosus inositol monophosphatase 1 0.0083 0.0499 0.0499
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0032 0.0117 0.0305
Trypanosoma brucei glucose transporter, putative 0.0071 0.0406 0.1056
Leishmania major cytochrome p450-like protein 0.0056 0.0299 0.0808
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0056 0.0299 0.0861
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0056 0.0299 0.0767
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Brugia malayi lysyl-tRNA synthetase 0.0051 0.0258 0.0354
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0347 0.0896
Brugia malayi Major Facilitator Superfamily protein 0.0032 0.0117 0.016
Leishmania major short chain dehydrogenase/reductase, putative 0.0029 0.0093 0.025
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0192 0.1319 0.1813
Trichomonas vaginalis sugar transporter, putative 0.0071 0.0406 0.1095
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0051 0.0258 0.0734
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0347 0.0896
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0025 0.0065 0.0148
Mycobacterium ulcerans oxidoreductase 0.0029 0.0093 0.0232
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0029 0.0093 0.0745
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0056 0.0299 0.0861
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Mycobacterium ulcerans short-chain dehydrogenase 0.0029 0.0093 0.0232
Toxoplasma gondii aldehyde dehydrogenase 0.0457 0.3304 0.7025
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0127
Mycobacterium ulcerans integral membrane transport protein 0.0032 0.0117 0.0305
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0056 0.0299 0.0861
Echinococcus multilocularis solute carrier family 22 0.0032 0.0117 0.0117
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0025 0.0065 0.0148
Trichomonas vaginalis myo-inositol transporter, putative 0.0032 0.0117 0.0315
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0029 0.0093 0.025
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0056 0.0299 0.0861
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0428 0.3086 0.3086
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0056 0.0299 0.0861
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0029 0.0093 0.0093
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0042 0.0188 0.0188
Mycobacterium ulcerans short chain dehydrogenase 0.0029 0.0093 0.0232
Onchocerca volvulus 0.0032 0.0117 0.016
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0025 0.0065 0.0176
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0025 0.0065 0.0132
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0192 0.1319 0.3558
Giardia lamblia Alcohol dehydrogenase 0.0025 0.0065 0.0374
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Brugia malayi Cytochrome P450 family protein 0.0066 0.0371 0.0511
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.016
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0068 0.0389 0.0534
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0188 0.0509
Mycobacterium ulcerans aldehyde dehydrogenase 0.0457 0.3304 1
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0093 0.025
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0029 0.0093 0.0232
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Echinococcus multilocularis carbonyl reductase 1 0.0029 0.0093 0.0093
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0056 0.0299 0.0861
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0029 0.0093 0.0127
Plasmodium vivax sugar transporter, putative 0.0032 0.0117 0.0164
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0056 0.0299 0.0861
Mycobacterium ulcerans short-chain dehydrogenase 0.0029 0.0093 0.0232
Schistosoma mansoni caspase-7 (C14 family) 0.135 1 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0511 0.3705 1
Leishmania major hypothetical protein, conserved 0.0029 0.0093 0.025
Leishmania major 3-keto-dihydrosphingosine reductase 0.0029 0.0093 0.025
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Trichomonas vaginalis sugar transporter, putative 0.0071 0.0406 0.1095
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0093 0.025
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.007 0.0403 0.0403
Toxoplasma gondii sugar transporter ST1 0.0032 0.0117 0.0248
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0029 0.0093 0.0232
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0192 0.1319 0.3558
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315
Loa Loa (eye worm) inositol-1 0.0083 0.0499 0.0686
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0025 0.0065 0.0065
Echinococcus granulosus carbonyl reductase 1 0.0029 0.0093 0.0093
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0457 0.3304 0.3304
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0056 0.0299 0.0861
Echinococcus multilocularis solute carrier family 22 0.0032 0.0117 0.0117
Loa Loa (eye worm) cytochrome P450 0.0056 0.0299 0.0412
Onchocerca volvulus 0.0029 0.0093 0.0127
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0025 0.0065 0.0148
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0511 0.3705 1
Leishmania major quinonoid dihydropteridine reductase 0.0029 0.0093 0.025
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0068 0.0389 0.0534
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0127
Trypanosoma brucei short-chain dehydrogenase, putative 0.0029 0.0093 0.0207
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.011 0.0705 0.0705
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0056 0.0299 0.0861
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0042 0.0188 0.0509
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.011 0.0705 0.0705
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0093 0.0197
Mycobacterium ulcerans ketoacyl reductase 0.0029 0.0093 0.0232
Brugia malayi hypoxia-induced factor 1 0.0495 0.3591 0.4938
Mycobacterium ulcerans sugar transporter 0.0032 0.0117 0.0305
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0025 0.0065 0.0176
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0511 0.3705 0.788
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0025 0.0065 0.0148
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0016 0.0124
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0029 0.0093 0.0207
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.1336 0.3605
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0045 0.0211 0.0568
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0117 0.0315

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 Increase in endogenous C16-ceramide level in human MCF7 cells at 10 uM upto 0.5 hrs ChEMBL. 17881234
Activity (functional) 0 Increase in endogenous C24-ceramide level in human MCF7 cells at 10 uM upto 0.5 hrs ChEMBL. 17881234
Activity (functional) 0 Increase in endogenous C24:1-ceramide level in human MCF7 cells at 10 uM upto 0.5 hrs ChEMBL. 17881234
Activity (functional) 0 Decrease in endogenous sphingosine level in human MCF7 cells at 10 uM upto 0.5 hrs ChEMBL. 17881234
Activity (functional) 0 Increase in endogenous sphingosine-1-phosphate level in human MCF7 cells after 5 to 10 hrs ChEMBL. 17881234
Activity (functional) = 130 % Increase in endogenous C24-ceramide level in human MCF7 cells upto 24 hrs ChEMBL. 17881234
Activity (functional) = 130 % Increase in endogenous C24-ceramide level in human MCF7 cells upto 24 hrs ChEMBL. 17881234
Activity (functional) = 140 % Increase in endogenous C24-ceramide level in human MCF7 cells after 24 hrs ChEMBL. 17881234
Activity (functional) = 140 % Increase in endogenous C24-ceramide level in human MCF7 cells after 24 hrs ChEMBL. 17881234
Activity (functional) = 260 % Increase in endogenous C24:1-ceramide level in human MCF7 cells upto 24 hrs ChEMBL. 17881234
Activity (functional) = 260 % Increase in endogenous C24:1-ceramide level in human MCF7 cells upto 24 hrs ChEMBL. 17881234
Activity (functional) = 270 % Increase in endogenous C24:1-ceramide level in human MCF7 cells after 24 hrs ChEMBL. 17881234
Activity (functional) = 270 % Increase in endogenous C24:1-ceramide level in human MCF7 cells after 24 hrs ChEMBL. 17881234
Activity (functional) = 350 % Increase in endogenous sphingosine level in human MCF7 cells after 24 hrs ChEMBL. 17881234
Activity (functional) = 350 % Increase in endogenous sphingosine level in human MCF7 cells after 24 hrs ChEMBL. 17881234
Activity (functional) = 760 % Increase in endogenous C14-ceramide level in human MCF7 cells at 10 uM upto 24 hrs ChEMBL. 17881234
Activity (functional) = 760 % Increase in endogenous C14-ceramide level in human MCF7 cells at 10 uM upto 24 hrs ChEMBL. 17881234
Activity (functional) = 800 % Increase in endogenous C16-ceramide level in human MCF7 cells after 24 hrs ChEMBL. 17881234
Activity (functional) = 800 % Increase in endogenous C14-ceramide level in human MCF7 cells after 24 hrs ChEMBL. 17881234
Activity (functional) = 800 % Increase in endogenous C16-ceramide level in human MCF7 cells after 24 hrs ChEMBL. 17881234
Activity (functional) = 800 % Increase in endogenous C14-ceramide level in human MCF7 cells after 24 hrs ChEMBL. 17881234
Activity (functional) = 820 % Increase in endogenous C16-ceramide level in human MCF7 cells upto 24 hrs ChEMBL. 17881234
Activity (functional) = 820 % Increase in endogenous C16-ceramide level in human MCF7 cells upto 24 hrs ChEMBL. 17881234

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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