Detailed information for compound 619550

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 343.349 | Formula: C14H15F2N3O3S
  • H donors: 1 H acceptors: 2 LogP: 2.19 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: C/N=C\1/SC(C(=O)N1C)CC(=O)Nc1ccccc1OC(F)F
  • InChi: 1S/C14H15F2N3O3S/c1-17-14-19(2)12(21)10(23-14)7-11(20)18-8-5-3-4-6-9(8)22-13(15)16/h3-6,10,13H,7H2,1-2H3,(H,18,20)/b17-14+
  • InChiKey: UEPRAXTWCPGZBP-SAPNQHFASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0313 0.098 0.098
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0042 0.0085 0.0134
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0101 0.0281 0.0281
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0111 0.0314 0.2217
Brugia malayi Cytochrome P450 family protein 0.0165 0.0491 0.0491
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Leishmania major hypothetical protein, conserved 0.0262 0.0813 0.5748
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0108 0.017
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0042 0.0085 0.0586
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0034 0.0058 0.0058
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0003 0.0026
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0104 0.0104
Echinococcus granulosus mixed lineage leukemia protein mll 0.0034 0.0058 0.0058
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0041 0.0081 0.0081
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0013 0.004
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0296 0.0924 0.1489
Loa Loa (eye worm) hypothetical protein 0.0496 0.1587 0.1587
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0022 0.0018 0.0108
Schistosoma mansoni cpg binding protein 0.0117 0.0333 0.0333
Schistosoma mansoni microtubule-associated protein tau 0.1463 0.4782 0.4782
Echinococcus multilocularis thyroid hormone receptor alpha 0.0082 0.0218 0.0218
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0108 0.1167
Echinococcus granulosus ecdysone induced protein 78C 0.0082 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0013
Mycobacterium tuberculosis Conserved protein 0.0296 0.0924 0.1489
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0317 0.0995 0.0995
Mycobacterium leprae conserved hypothetical protein 0.0296 0.0924 1
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0262 0.0813 0.3721
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0444 0.1415 0.2282
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.02 0.0606 0.6159
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0026 0.0082
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0024 0.0027 0.0194
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0262 0.0813 0.0813
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0108 0.1095
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0314 0.0985 1
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0024 0.0027 0.0194
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.02 0.0606 0.0606
Leishmania major glycerol uptake protein, putative 0.0262 0.0813 0.5748
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.0356 0.0356
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.002 0.0013 0.0013
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.002 0.0013 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0042 0.0085 0.0134
Schistosoma mansoni hypothetical protein 0.0317 0.0995 0.0995
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0093 0.0941
Schistosoma mansoni lipoxygenase 0.0188 0.057 0.057
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0151 0.0447 0.0718
Echinococcus multilocularis muscleblind protein 1 0.1094 0.3563 0.3563
Loa Loa (eye worm) glutathione reductase 0.0049 0.0108 0.0108
Plasmodium falciparum ornithine aminotransferase 0.0022 0.0018 0.0219
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.0813 0.2522
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0086 0.0086
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0019 0.0019
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.002 0.0013 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0042 0.0085 0.0134
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0042 0.0085 0.0134
Entamoeba histolytica protein kinase, putative 0.0094 0.0256 0.1173
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0012 0.0126
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0024 0.0027 0.0177
Trichomonas vaginalis penicillin-binding protein, putative 0.0296 0.0924 0.2866
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0012 0.0126
Brugia malayi hypothetical protein 0.0079 0.0207 0.0207
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.002 0.0013 0.0013
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0207 0.2102
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0111 0.0314 0.3185
Brugia malayi nuclear hormone receptor family member nhr-6 0.0039 0.0075 0.0075
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0024 0.0027 0.0027
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.02 0.0606 0.4287
Loa Loa (eye worm) MBOAT family protein 0.0262 0.0813 0.0813
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0082 0.0218 0.0218
Mycobacterium tuberculosis Probable lipase LipE 0.0296 0.0924 0.1489
Echinococcus granulosus intermediate filament protein 0.0026 0.0034 0.0034
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0262 0.0813 0.0813
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0012 0.0126
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0042 0.0085 0.0134
Loa Loa (eye worm) histone methyltransferase 0.0041 0.0081 0.0081
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.02 0.0606 0.6159
Schistosoma mansoni cpg binding protein 0.0125 0.0361 0.0361
Giardia lamblia DINP protein human, muc B family 0.002 0.0012 0.0057
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0026
Schistosoma mansoni GTP-binding protein alpha subunit 0.002 0.0013 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0012 0.0126
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0064 0.0295
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0019 0.0193
Echinococcus granulosus RUN 0.0042 0.0086 0.0086
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0444 0.1415 0.1415
Loa Loa (eye worm) hypothetical protein 0.0253 0.0782 0.0782
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0022 0.0018 0.5606
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.002 0.0013 0.004
Brugia malayi beta-lactamase family protein 0.0296 0.0924 0.0924
Brugia malayi RNA binding protein 0.0061 0.0149 0.0149
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0012 0.0126
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.002 0.0013 0.004
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0871 0.2827 0.2827
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0024 0.0027 0.0279
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0262 0.0813 0.0813
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0022 0.0018 0.0126
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0111 0.0314 0.327
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0013 0.004
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0024 0.0027 0.0027
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0104 0.0104
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0012 0.0126
Schistosoma mansoni nuclear receptor nhr-48 0.0039 0.0075 0.0075
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0151 0.0444 0.0444
Echinococcus granulosus beta LACTamase domain containing family member 0.0296 0.0924 0.0924
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0188 0.057 0.057
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.003 0.0136
Entamoeba histolytica Ran family GTPase 0.0022 0.0019 0.0087
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0091 0.0247 0.0765
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0003 0.0003
Schistosoma mansoni importin beta-1 0.003 0.0045 0.0045
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.02 0.0606 0.2775
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0013 0.0013
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.002 0.0013 0.0013
Leishmania major GTP-binding protein, putative 0.0022 0.0019 0.0134
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0024 0.0027 0.0027
Brugia malayi hypothetical protein 0.0253 0.0782 0.0782
Schistosoma mansoni thyroid hormone receptor 0.0082 0.0218 0.0218
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0066 0.0066
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0003
Loa Loa (eye worm) hhat protein 0.0262 0.0813 0.0813
Brugia malayi CXXC zinc finger family protein 0.0117 0.0333 0.0333
Schistosoma mansoni eyes absent homolog 0.0094 0.0258 0.0258
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0012 0.0126
Toxoplasma gondii exonuclease III APE 0.0059 0.0142 0.1005
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0003 0.0027
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0019 0.0193
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0013 0.004
Loa Loa (eye worm) hypothetical protein 0.0056 0.0133 0.0133
Brugia malayi Hhat protein 0.0262 0.0813 0.0813
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0082 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0013
Brugia malayi steroid hormone receptor 0.0082 0.0218 0.0218
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0059 0.0142 0.1444
Echinococcus multilocularis sentrin specific protease 7 0.0025 0.003 0.003
Trypanosoma brucei SUMO1/Ulp2, putative 0.0025 0.003 0.0302
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.003 0.0136
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0024 0.0027 0.0279
Schistosoma mansoni zinc finger protein 0.0039 0.0075 0.0075
Trypanosoma brucei glycerol uptake protein, putative 0.0262 0.0813 0.8257
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0012 0.0012
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0024 0.0027 0.0279
Onchocerca volvulus 0.0026 0.0034 0.0105
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0296 0.0924 0.1489
Mycobacterium leprae Conserved hypothetical protein 0.0042 0.0085 0.0745
Entamoeba histolytica hypothetical protein 0.0299 0.0935 0.4277
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0024 0.0027 0.004
Schistosoma mansoni nuclear hormone receptor 0.0082 0.0218 0.0218
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0296 0.0924 0.1489
Mycobacterium ulcerans aldehyde dehydrogenase 0.0444 0.1415 1
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0314 0.0973
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0252 0.0781 0.0781
Loa Loa (eye worm) hypothetical protein 0.0082 0.0218 0.0218
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0024 0.0027 0.0194
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0024 0.0027 0.0177
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0012 0.0012
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0042 0.0085 0.0586
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0018 0.0108
Trypanosoma brucei unspecified product 0.002 0.0012 0.0126
Brugia malayi Nuclear hormone receptor-like 1 0.0082 0.0218 0.0218
Echinococcus granulosus guanine nucleotide binding protein G protein 0.002 0.0013 0.0013
Trichomonas vaginalis porcupine, putative 0.0262 0.0813 0.2522
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0003 0.0031
Echinococcus multilocularis tumor protein p63 0.1367 0.4466 0.4466
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0034 0.0058 0.0058
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0299 0.0935 0.0935
Schistosoma mansoni zinc finger protein 0.0034 0.0058 0.0058
Mycobacterium ulcerans beta-lactamase 0.0296 0.0924 0.6525
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0106
Schistosoma mansoni DNA polymerase eta 0.002 0.0012 0.0012
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0019 0.0134
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0008
Schistosoma mansoni ran 0.0022 0.0019 0.0019
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0024 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0106
Schistosoma mansoni hypothetical protein 0.0042 0.0085 0.0085
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0082 0.0218 0.0218
Schistosoma mansoni inositol monophosphatase 0.0036 0.0066 0.0066
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0039 0.0075 0.0075
Schistosoma mansoni bromodomain containing protein 0.0018 0.0008 0.0008
Mycobacterium tuberculosis Conserved protein 0.0296 0.0924 0.1489
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0024 0.0027 0.004
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0066 0.0205
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0043 0.009 0.009
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0082 0.0218 0.0218
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0024 0.0027 0.0126
Toxoplasma gondii histone lysine methyltransferase SET1 0.0236 0.0727 0.5137
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0082 0.0218 0.0218
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0082 0.0218 0.0218
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0066 0.4547
Schistosoma mansoni thyroid hormone receptor 0.0082 0.0218 0.0218
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0082 0.0218 0.0218
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0111 0.0314 0.2217
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.002 0.0013 0.0013
Echinococcus multilocularis sentrin specific protease 8 0.0025 0.003 0.003
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0108 0.0108
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0022 0.0018 0.0025
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0094 0.0256 0.181
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0082 0.0218 0.0218
Trichomonas vaginalis penicillin-binding protein, putative 0.0296 0.0924 0.2866
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0151 0.0447 0.1386
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0104 0.0104
Schistosoma mansoni ran 0.0022 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0048 0.0104 0.0104
Schistosoma mansoni GTP-binding protein alpha subunit 0.002 0.0013 0.0013
Echinococcus multilocularis sterol O acyltransferase 1 0.0262 0.0813 0.0813
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0024 0.0027 0.0177
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0059 0.0142 0.0989
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.003 0.0092
Brugia malayi G-protein alpha subunit 0.002 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0082 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0082 0.0218 0.0218
Brugia malayi hypothetical protein 0.0299 0.0935 0.0935
Onchocerca volvulus 0.0262 0.0813 0.2522
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0082 0.0218 0.0218
Loa Loa (eye worm) beta-lactamase 0.0296 0.0924 0.0924
Schistosoma mansoni hypothetical protein 0.0101 0.0281 0.0281
Trypanosoma cruzi GUP1, putative 0.0262 0.0813 0.8257
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0466 0.1488 0.1488
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0262 0.0813 0.0813
Loa Loa (eye worm) hypothetical protein 0.0025 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0106
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0262 0.0813 0.0813
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0024 0.0027 0.0177
Giardia lamblia Sentrin specific protease, putative 0.0025 0.003 0.0136
Mycobacterium ulcerans L-lysine aminotransferase 0.0022 0.0018 0.0108
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0013 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0149 0.0149
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0066 0.0671
Echinococcus multilocularis neuropeptide s receptor 0.099 0.3219 0.3219
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0024 0.0027 0.0027
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0082 0.0218 0.0218
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0012 0.0126
Mycobacterium tuberculosis Conserved hypothetical protein 0.0165 0.0493 0.0793
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0012 0.0126
Trypanosoma cruzi hypothetical protein, conserved 0.0296 0.0924 0.9382
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0677 0.2185 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0034 0.0106
Leishmania major aldehyde dehydrogenase, putative 0.0024 0.0027 0.0194
Echinococcus granulosus histone acetyltransferase KAT2B 0.0302 0.0943 0.0943
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0064 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0106
Loa Loa (eye worm) hypothetical protein 0.0079 0.0207 0.0207
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0086 0.0086
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.003 0.0136
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0082 0.0218 0.0218
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0042 0.0085 0.0586
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0064 0.02
Trichomonas vaginalis sentrin/sumo-specific protease, senp8, putative 0.0025 0.003 0.0092
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0042 0.0085 0.0134
Schistosoma mansoni aldehyde dehydrogenase 0.0444 0.1415 0.1415
Brugia malayi Calcitonin receptor-like protein seb-1 0.0151 0.0444 0.0444
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0142 0.1749
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0042 0.0085 0.0586
Brugia malayi Cytochrome P450 family protein 0.0061 0.0149 0.0149
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0024 0.0027 0.0027
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0012 0.0088
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0151 0.0447 0.3146
Trypanosoma cruzi GUP1, putative 0.0262 0.0813 0.8257
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0111 0.0314 0.0314
Chlamydia trachomatis deubiquitinase/deneddylase Dub2 0.0025 0.003 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0003
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0003 0.0018
Echinococcus multilocularis mitogen activated protein kinase 3 0.0111 0.0314 0.0314
Schistosoma mansoni lamin 0.0026 0.0034 0.0034
Echinococcus granulosus dnaJ subfamily B 0.1261 0.4115 0.4115
Echinococcus granulosus ubiquitin specific protease 41 0.02 0.0606 0.0606
Mycobacterium tuberculosis Probable hydrolase 0.0296 0.0924 0.1489
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0022 0.0018 0.0025
Onchocerca volvulus 0.0991 0.3223 1
Leishmania major hypothetical protein, conserved 0.0079 0.0207 0.1463
Echinococcus multilocularis FTZ F1 alpha 0.0082 0.0218 0.0218
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0034 0.0106
Mycobacterium ulcerans hypothetical protein 0.0151 0.0447 0.3146
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0106
Schistosoma mansoni hypothetical protein 0.0262 0.0813 0.0813
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0104 0.0104
Plasmodium vivax SET domain protein, putative 0.0127 0.0367 0.3973
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0042 0.0085 0.0134
Brugia malayi follicle stimulating hormone receptor 0.0478 0.1526 0.1526
Echinococcus granulosus tar DNA binding protein 0.0061 0.0149 0.0149
Trypanosoma brucei cytochrome P450, putative 0.0061 0.0149 0.151
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0142 0.0441
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0012 0.0126
Schistosoma mansoni hypothetical protein 0.0176 0.0528 0.0528
Onchocerca volvulus 0.0025 0.003 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.0813 0.2522
Brugia malayi photoreceptor-specific nuclear receptor 0.0082 0.0218 0.0218
Mycobacterium leprae PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDE 0.0024 0.0027 0.0107
Echinococcus granulosus guanine nucleotide binding protein G protein 0.002 0.0013 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0082 0.0218 0.0218
Plasmodium vivax glutathione reductase, putative 0.0049 0.0108 0.1167
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0111 0.0314 0.0504
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0149 0.0438 0.4448
Loa Loa (eye worm) hypothetical protein 0.0024 0.0027 0.0027
Echinococcus granulosus o acyltransferase membrane bound domain 0.0262 0.0813 0.0813
Echinococcus multilocularis expressed protein 0.002 0.0013 0.0013
Brugia malayi hypothetical protein 0.0043 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0024 0.0027 0.0027
Trypanosoma cruzi cytochrome P450, putative 0.0061 0.0149 0.151
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0064 0.0064
Echinococcus multilocularis survival motor neuron protein 1 0.0496 0.1587 0.1587
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0108 0.0108
Schistosoma mansoni hypothetical protein 0.0176 0.0528 0.0528
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0025 0.003 0.003
Brugia malayi aldehyde dehydrogenase 0.0024 0.0027 0.0027
Loa Loa (eye worm) RNA binding protein 0.0061 0.0149 0.0149
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0019 0.0234
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0059 0.0142 0.1005
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0296 0.0924 0.0924
Loa Loa (eye worm) CXXC zinc finger family protein 0.0117 0.0333 0.0333
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0002 0.0002
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0043 0.009 0.009
Schistosoma mansoni sterol O-acyltransferase 1 0.0262 0.0813 0.0813
Brugia malayi nuclear receptor NHR-67 0.0039 0.0075 0.0075
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1889 0.619 1
Echinococcus granulosus FTZ F1 alpha 0.0082 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0042 0.0086 0.0086
Echinococcus granulosus o acyltransferase membrane bound domain 0.0262 0.0813 0.0813
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0022 0.0018 0.0018
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.0256 0.1173
Echinococcus multilocularis geminin 0.0176 0.0528 0.0528
Echinococcus multilocularis ubiquitin specific protease 41 0.02 0.0606 0.0606
Wolbachia endosymbiont of Brugia malayi bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 0.0024 0.0027 0.1787
Brugia malayi hypothetical protein 0.0094 0.0258 0.0258
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.003 0.003
Brugia malayi hypothetical protein 0.0039 0.0075 0.0075
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0042 0.0085 0.0134
Brugia malayi Pre-SET motif family protein 0.0871 0.2827 0.2827
Loa Loa (eye worm) hypothetical protein 0.0043 0.009 0.009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0082 0.0218 0.0218
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0042 0.0085 0.0586
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0042 0.0085 0.0134
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0082 0.0218 0.0676
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0042 0.0085 0.0586
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0091 0.0247 0.0247
Onchocerca volvulus 0.0117 0.0333 0.1033
Entamoeba histolytica hypothetical protein 0.0299 0.0935 0.4277
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0059 0.0142 0.0142
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0314 0.0985 1
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.002 0.0013 0.0013
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0064 0.0064
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0012 0.0012
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0314 0.0985 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0296 0.0924 0.0924
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0466 0.1488 0.1488
Schistosoma mansoni transcription factor LCR-F1 0.0299 0.0935 0.0935
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0024 0.0027 0.004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0144 0.0423 0.0423
Trypanosoma brucei glucosidase, putative 0.0036 0.0064 0.0654
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.002 0.0013 0.0013
Plasmodium vivax importin-beta 2, putative 0.003 0.0045 0.0486
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.009 0.009
Brugia malayi Pre-SET motif family protein 0.0127 0.0367 0.0367
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0091 0.0247 0.0247
Plasmodium vivax ornithine aminotransferase, putative 0.0022 0.0018 0.0193
Schistosoma mansoni cpg binding protein 0.0125 0.0361 0.0361
Echinococcus multilocularis dual specificity 0.0094 0.0256 0.0256
Trypanosoma brucei protein kinase, putative 0.0111 0.0314 0.3185
Loa Loa (eye worm) acetyltransferase 0.0313 0.098 0.098
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0024 0.0027 0.0027
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0082 0.0218 0.0218
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0034 0.0106
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0042 0.0085 0.0134
Loa Loa (eye worm) CYP4Cod1 0.0061 0.0149 0.0149
Schistosoma mansoni hypothetical protein 0.1261 0.4115 0.4115
Brugia malayi hypothetical protein 0.0496 0.1587 0.1587
Trichomonas vaginalis esterase, putative 0.0296 0.0924 0.2866
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0018 0.0018
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.003 0.0092
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0144 0.0423 0.0423
Mycobacterium ulcerans acetylornithine aminotransferase 0.0022 0.0018 0.0108
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0082 0.0218 0.0218
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.02 0.0606 0.2775
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0075 0.0075
Onchocerca volvulus 0.0296 0.0924 0.2866
Leishmania major glycerol uptake protein, putative 0.0262 0.0813 0.5748
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0019 0.0206
Loa Loa (eye worm) hypothetical protein 0.02 0.0608 0.0608
Brugia malayi beta-lactamase family protein 0.0296 0.0924 0.0924
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0262 0.0813 0.0813
Trypanosoma cruzi glycerol uptake protein, putative 0.0262 0.0813 0.8257
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0064 0.02
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0438 0.3096
Schistosoma mansoni retinoic acid receptor RXR 0.0082 0.0218 0.0218
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0477 0.0477
Brugia malayi nuclear hormone receptor family member odr-7 0.0039 0.0075 0.0075
Mycobacterium leprae PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT 0.0024 0.0027 0.0107
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0024 0.0027 0.0279
Loa Loa (eye worm) aldehyde dehydrogenase 0.0024 0.0027 0.0027
Schistosoma mansoni aldehyde dehydrogenase 0.0024 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.02 0.0606 0.1881
Schistosoma mansoni zinc finger protein 0.3041 1 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0094 0.0256 0.2771
Schistosoma mansoni polycystin 1-related 0.0042 0.0086 0.0086
Echinococcus multilocularis lamin dm0 0.0026 0.0034 0.0034
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0024 0.0027 0.0177
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0024 0.0027 0.0177
Loa Loa (eye worm) hypothetical protein 0.02 0.0606 0.0606
Echinococcus multilocularis neuropeptide receptor A26 0.099 0.3219 0.3219
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0026
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Plasmodium falciparum thioredoxin reductase 0.0049 0.0108 0.1326
Brugia malayi MBOAT family protein 0.0262 0.0813 0.0813
Plasmodium falciparum glutathione reductase 0.0017 0.0003 0.0031
Brugia malayi ecdysone receptor 0.0039 0.0075 0.0075
Brugia malayi Inositol-1 0.0036 0.0066 0.0066
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.003 0.0092
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0149 0.0149
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.002 0.0013 0.0013
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0064 0.02
Trypanosoma cruzi glycerol uptake protein, putative 0.0262 0.0813 0.8257
Leishmania major glycerol uptake protein, putative 0.0262 0.0813 0.5748
Trypanosoma cruzi cytochrome P450, putative 0.0061 0.0149 0.151
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0262 0.0813 0.0813
Echinococcus granulosus o acyltransferase membrane bound domain 0.0262 0.0813 0.0813
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0024 0.0027 0.0279
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0093 0.0941
Echinococcus multilocularis Aminotransferase class III 0.0022 0.0018 0.0018
Brugia malayi exodeoxyribonuclease III family protein 0.0059 0.0142 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0082 0.0218 0.0218
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0082 0.0218 0.0218
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0019 0.0019
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0082 0.0218 0.0218
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0262 0.0813 0.0813
Schistosoma mansoni alpha-glucosidase 0.0138 0.0403 0.0403
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0082 0.0218 0.0218
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0024 0.0027 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0256 0.0256
Loa Loa (eye worm) hypothetical protein 0.0091 0.0247 0.0247
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0024 0.0027 0.004
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0025 0.003 0.0211
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0207 0.2546
Trypanosoma cruzi hypothetical protein, conserved 0.0296 0.0924 0.9382
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0477 0.0477
Onchocerca volvulus 0.0296 0.0924 0.2866
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0042 0.0085 0.0866
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0466 0.1488 0.1488
Loa Loa (eye worm) hypothetical protein 0.0296 0.0924 0.0924
Plasmodium vivax sentrin-specific protease 2, putative 0.0025 0.003 0.0322
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0106
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0094 0.0256 0.0794
Loa Loa (eye worm) hypothetical protein 0.0048 0.0104 0.0104
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0042 0.0085 0.0586
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0024 0.0027 0.0194
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0262 0.0813 0.0813
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0034 0.0034
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0024 0.0027 0.0279
Plasmodium falciparum glutathione reductase 0.0049 0.0108 0.1326
Brugia malayi Thioredoxin reductase 0.0049 0.0108 0.0108
Onchocerca volvulus Protein ultraspiracle homolog 0.0082 0.0218 0.0676
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0013 0.0013
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0064 0.0455
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0024 0.0027 0.0085
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0438 0.4448
Schistosoma mansoni alpha-glucosidase 0.0138 0.0403 0.0403
Echinococcus granulosus mitogen activated protein kinase 0.0111 0.0314 0.0314
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0039 0.0075 0.0075
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.0188 0.0188
Entamoeba histolytica acetyltransferase, GNAT family 0.0084 0.0223 0.1021
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0026
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0019 0.0087
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.002 0.0013 0.0013
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0024 0.0027 0.0279
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0019 0.0019
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0024 0.0027 0.0279
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0034 0.0106
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0066 0.0467
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0024 0.0027 0.0177
Brugia malayi conserved hypotetical protein 0.0039 0.0075 0.0075
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0045 0.0456
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0042 0.0085 0.0134
Plasmodium vivax hypothetical protein, conserved 0.0296 0.0924 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0084 0.0223 0.2745
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0042 0.0042
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0024 0.0027 0.0279
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0082 0.0218 0.0218
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.0149 0.0149
Trypanosoma brucei PAB1-binding protein , putative 0.0079 0.0207 0.2102
Trichomonas vaginalis bromodomain-containing protein, putative 0.0094 0.0256 0.0794
Echinococcus granulosus mitogen activated protein kinase 3 0.0111 0.0314 0.0314
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0059 0.0142 0.0142
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0061 0.0149 0.1035
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0024 0.0027 0.0279
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0094 0.0256 0.181
Mycobacterium leprae putative cytochrome p450 0.0042 0.0085 0.0745
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0042 0.0085 0.0866
Echinococcus multilocularis importin subunit beta 1 0.003 0.0045 0.0045
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0024 0.0027 0.0177
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0149 0.0149
Echinococcus multilocularis GPCR, family 2 0.0048 0.0104 0.0104
Entamoeba histolytica hypothetical protein, conserved 0.0262 0.0813 0.3721
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0188 0.057 0.057
Loa Loa (eye worm) hypothetical protein 0.0025 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0092 0.0251 0.0251
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0024 0.0027 0.0279
Echinococcus granulosus muscleblind protein 0.1094 0.3563 0.3563
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.009 0.009
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0086 0.106
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0086 0.0086
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0012 0.0126
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0042 0.0085 0.0134
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0262 0.0813 0.0813
Toxoplasma gondii cytochrome p450 superfamily protein 0.0042 0.0085 0.0603
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.003 0.0136
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.003 0.0092
Loa Loa (eye worm) MBOAT family protein 0.3041 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0082 0.0218 0.0218
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0064 0.02
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.003 0.0092
Echinococcus multilocularis musashi 0.0026 0.0034 0.0034
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0042 0.0042
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.002 0.0013 0.0013
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0314 0.3185
Trichomonas vaginalis D-aminoacylase, putative 0.0296 0.0924 0.2866
Schistosoma mansoni steroid hormone receptor ad4bp 0.0082 0.0218 0.0218
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0025 0.003 0.0302
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.002 0.0013 0.0013
Trypanosoma cruzi hypothetical protein 0.0025 0.003 0.0302
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0024 0.0027 0.0027
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0012 0.0012
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0207 0.2102
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0086 0.0086
Schistosoma mansoni nuclear receptor 0.0039 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0013
Onchocerca volvulus 0.02 0.0608 0.1887
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0042 0.0085 0.0586
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0262 0.0813 0.0813
Brugia malayi diacylglycerol acyltransferase 0.0262 0.0813 0.0813
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0012 0.0039
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0059 0.0142 0.1444
Echinococcus granulosus thyroid hormone receptor alpha 0.0039 0.0075 0.0075
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0059 0.0142 0.0651
Schistosoma mansoni cytochrome P450 0.0042 0.0085 0.0085
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0064 0.0064
Schistosoma mansoni rab6-interacting 0.0042 0.0086 0.0086
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0022 0.0018 0.0108
Echinococcus granulosus sterol O acyltransferase 1 0.0262 0.0813 0.0813
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0296 0.0924 0.0924
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0094 0.0256 0.2603
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0104 0.0104
Schistosoma mansoni ap endonuclease 0.0059 0.0142 0.0142
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0466 0.1488 0.1488
Brugia malayi intermediate filament protein 0.0026 0.0034 0.0034
Loa Loa (eye worm) MBOAT family protein 0.0262 0.0813 0.0813
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0149 0.0149
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0034 0.0034
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0262 0.0813 0.0813
Mycobacterium tuberculosis Probable lipase LipD 0.0296 0.0924 0.1489
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0075 0.0075
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.002 0.0013 0.0013
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.02 0.0606 0.0606
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0045 0.0456
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0013
Schistosoma mansoni bromodomain containing protein 0.0077 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0072
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0082 0.0218 0.0218
Schistosoma mansoni alpha glucosidase 0.0036 0.0064 0.0064
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0024 0.0027 0.004
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0299 0.0935 0.0935
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.003 0.0092
Onchocerca volvulus 0.002 0.0013 0.004
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0444 0.1415 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0032
Echinococcus granulosus tumor protein p63 0.1367 0.4466 0.4466
Brugia malayi beta-lactamase 0.0296 0.0924 0.0924
Schistosoma mansoni cellular tumor antigen P53 0.02 0.0608 0.0608
Loa Loa (eye worm) hypothetical protein 0.0144 0.0423 0.0423
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0082 0.0218 0.0218
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0059 0.0142 0.0651
Trichomonas vaginalis D-aminoacylase, putative 0.0296 0.0924 0.2866
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0026
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.002 0.0013 0.004
Toxoplasma gondii thioredoxin reductase 0.0049 0.0108 0.0762
Trichomonas vaginalis helicase, putative 0.0026 0.0034 0.0106
Loa Loa (eye worm) bromodomain containing protein 0.0025 0.0029 0.0029
Brugia malayi Importin beta-1 subunit 0.003 0.0045 0.0045
Echinococcus multilocularis dnaJ subfamily B 0.1261 0.4115 0.4115
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0082 0.0218 0.0218
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0262 0.0813 1
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0314 0.0314
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0296 0.0924 0.0924
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0026
Leishmania major aldehyde dehydrogenase, putative 0.0024 0.0027 0.0194
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0024 0.0027 0.004
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0024 0.0027 0.004
Echinococcus granulosus microtubule associated protein 2 0.1463 0.4782 0.4782
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0142 0.0441
Loa Loa (eye worm) hypothetical protein 0.0048 0.0104 0.0104
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0082 0.0218 0.0218
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0477 0.0477
Loa Loa (eye worm) inositol-1 0.0036 0.0066 0.0066
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0042 0.0085 0.0586
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.002 0.0013 0.0013
Echinococcus granulosus snurportin 1 0.0317 0.0995 0.0995
Toxoplasma gondii hypothetical protein 0.0262 0.0813 0.5748
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0108 0.0108
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0064 0.02
Schistosoma mansoni hypothetical protein 0.0048 0.0104 0.0104
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0075 0.0075
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.02 0.0606 0.0606
Toxoplasma gondii ABC1 family protein 0.0296 0.0924 0.6531
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0022 0.0018 0.1094
Leishmania major cytochrome p450-like protein 0.0042 0.0085 0.0603
Schistosoma mansoni survival motor neuron protein 0.0101 0.0281 0.0281
Mycobacterium ulcerans aldehyde dehydrogenase 0.0444 0.1415 1
Treponema pallidum gamma-glutamyl phosphate reductase 0.0024 0.0027 0.0308
Brugia malayi TAR-binding protein 0.0061 0.0149 0.0149
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0066 0.0205
Brugia malayi MBOAT family protein 0.0262 0.0813 0.0813
Mycobacterium ulcerans aldehyde dehydrogenase 0.0024 0.0027 0.0177
Brugia malayi Muscleblind-like protein 0.1094 0.3563 0.3563
Entamoeba histolytica hypothetical protein 0.0193 0.0584 0.2671
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0299 0.0935 0.0935
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0066 0.0302
Brugia malayi hypothetical protein 0.0043 0.009 0.009
Entamoeba histolytica hypothetical protein 0.0299 0.0935 0.4277
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0012 0.0126
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0024 0.0027 0.0027
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0039 0.0075 0.0075
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0018 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0466 0.1488 0.1488
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0035 0.0063 0.0063
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0012 0.0016
Mycobacterium ulcerans hypothetical protein 0.0165 0.0493 0.3477
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0091 0.0247 0.0247
Entamoeba histolytica hypothetical protein 0.0299 0.0935 0.4277
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0082 0.0218 0.0218
Echinococcus multilocularis beta LACTamase domain containing family member 0.0296 0.0924 0.0924
Schistosoma mansoni lipoxygenase 0.0112 0.0318 0.0318
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0042 0.0085 0.0134
Toxoplasma gondii hypothetical protein 0.0051 0.0114 0.0807
Mycobacterium ulcerans aldehyde dehydrogenase 0.0444 0.1415 1
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0042 0.0085 0.0866
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.0024 0.0027 0.0107
Onchocerca volvulus 0.0026 0.0034 0.0105
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0313 0.098 0.098
Brugia malayi Cytochrome P450 family protein 0.0061 0.0149 0.0149
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0296 0.0924 0.0924
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0466 0.1488 0.1488
Echinococcus granulosus guanine nucleotide binding protein subunit 0.002 0.0013 0.0013
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0024 0.0027 0.0027
Brugia malayi hypothetical protein 0.0051 0.0115 0.0115
Schistosoma mansoni hypothetical protein 0.0048 0.0104 0.0104
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0149 0.0149
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.002 0.0013 0.0013
Schistosoma mansoni rab6-interacting 0.0042 0.0086 0.0086
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0091 0.0247 0.1744
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0025 0.003 0.0211
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0262 0.0813 0.3721
Echinococcus granulosus ornithine aminotransferase 0.0022 0.0018 0.0018
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0066 0.0671
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0034 0.0034
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0025 0.003 0.0211
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0003 0.0012
Plasmodium vivax ataxin-2 like protein, putative 0.0079 0.0207 0.224
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0024 0.0027 0.0027
Leishmania major glycerol uptake protein, putative 0.0262 0.0813 0.5748
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0064 0.0064
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0124 0.0355 0.3723
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0013 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0042 0.0085 0.0134
Mycobacterium tuberculosis Probable oxidoreductase 0.0124 0.0355 0.057
Schistosoma mansoni lamin 0.0026 0.0034 0.0034
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0262 0.0813 0.0813
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0149 0.0149
Schistosoma mansoni loxhd1 0.0042 0.0086 0.0086
Echinococcus multilocularis 0.0042 0.0085 0.0085
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0042 0.0085 0.0586
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0018
Loa Loa (eye worm) hypothetical protein 0.0082 0.0218 0.0218
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0093 0.0941
Echinococcus granulosus GPCR family 2 0.0048 0.0104 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0082 0.0218 0.0218
Schistosoma mansoni hypothetical protein 0.0024 0.0027 0.0027
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0026 0.0082
Echinococcus multilocularis dna polymerase kappa 0.002 0.0012 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0149 0.0149
Brugia malayi MBOAT family protein 0.0262 0.0813 0.0813
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0026
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0262 0.0813 0.0813
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0082 0.0218 0.0218
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0082 0.0218 0.0218
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0142 0.1539
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0043 0.009 0.009
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0094 0.0258 0.0258
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.003 0.003
Mycobacterium ulcerans esterase/lipase LipP 0.0296 0.0924 0.6525
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0034 0.0058 0.0058
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0018 0.0108
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0024 0.0027 0.004
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0124 0.0355 0.057
Leishmania major DNA polymerase kappa, putative 0.002 0.0012 0.0088
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0003 0.0008
Echinococcus granulosus zinc finger protein 0.0034 0.0058 0.0058
Brugia malayi PHD-finger family protein 0.0039 0.0075 0.0075
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0262 0.0813 0.0813
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0059 0.0142 0.0226
Onchocerca volvulus 0.002 0.0013 0.004
Echinococcus granulosus guanine nucleotide binding protein subunit 0.002 0.0013 0.0013
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0024 0.0027 0.0177
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0262 0.0813 0.8801
Brugia malayi hypothetical protein 0.002 0.0013 0.0013
Echinococcus granulosus neuropeptide s receptor 0.099 0.3219 0.3219
Plasmodium vivax SET domain containing protein 0.0017 0.0003 0.0034
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0012 0.0012
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.002 0.0013 0.0013
Brugia malayi Doublecortin family protein 0.0042 0.0086 0.0086
Schistosoma mansoni aldehyde dehydrogenase 0.0444 0.1415 0.1415
Echinococcus multilocularis sentrin specific protease 1 0.0091 0.0247 0.0247
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0262 0.0813 0.0813
Plasmodium vivax sentrin-specific protease 1, putative 0.0091 0.0247 0.267
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0144 0.0423 0.0423
Onchocerca volvulus 0.0082 0.0218 0.0676
Brugia malayi nuclear receptor NHR-88 0.0039 0.0075 0.0075
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.3041 1 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0034 0.0058 0.0058
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0091 0.0247 0.1129
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0054 0.0082
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0012 0.0057
Echinococcus multilocularis RUN 0.0042 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0048 0.0104 0.0104
Echinococcus multilocularis mitogen activated protein kinase 0.0111 0.0314 0.0314
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0064 0.0064
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0012 0.007
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0082 0.0218 0.0218
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0024 0.0027 0.004
Schistosoma mansoni aldehyde dehydrogenase 0.0024 0.0027 0.0027
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0042 0.0085 0.0586
Echinococcus granulosus expressed protein 0.002 0.0013 0.0013
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0024 0.0027 0.0194
Echinococcus granulosus nuclear receptor nhr 48 0.0039 0.0075 0.0075
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0314 0.3185
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0013 0.0013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0034 0.0106
Brugia malayi nuclear receptor RXR 0.0039 0.0075 0.0075
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.003 0.0092
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0111 0.0314 0.3185
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0043 0.009 0.009
Echinococcus multilocularis cpg binding protein 0.0125 0.0361 0.0361
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0149 0.0149
Onchocerca volvulus Huntingtin homolog 0.0253 0.0782 0.2427
Leishmania major aldehyde dehydrogenase, putative 0.0024 0.0027 0.0194
Trypanosoma brucei glycerol uptake protein, putative 0.0262 0.0813 0.8257
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0012 0.0126
Echinococcus granulosus sentrin specific protease 8 0.0025 0.003 0.003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0003 0.0026
Schistosoma mansoni RAR-like nuclear receptor 0.0082 0.0218 0.0218
Onchocerca volvulus 0.0039 0.0075 0.0232
Brugia malayi Aldehyde dehydrogenase protein 4 0.0024 0.0027 0.0027
Onchocerca volvulus Huntingtin homolog 0.0253 0.0782 0.2427
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0024 0.0027 0.0027
Mycobacterium tuberculosis Probable esterase LipL 0.0296 0.0924 0.1489
Giardia lamblia DNA repair protein RAD52 0.0677 0.2185 1
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.002 0.0013 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0082 0.0218 0.0218
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0024 0.0027 0.0177
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0024 0.0027 0.0279
Schistosoma mansoni aldehyde dehydrogenase 0.0024 0.0027 0.0027
Brugia malayi nuclear hormone receptor 0.0039 0.0075 0.0075
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0012 0.0016
Echinococcus multilocularis ecdysone induced protein 78C 0.0082 0.0218 0.0218
Loa Loa (eye worm) DR-78 0.0039 0.0075 0.0075
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0002 0.0002
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0111 0.0314 0.3185
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0024 0.0027 0.0126
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0024 0.0027 0.0194
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0444 0.1415 0.1415
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0039 0.0075 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0012 0.0126
Mycobacterium ulcerans hypothetical protein 0.0296 0.0924 0.6525
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0018
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.02 0.0606 0.1881
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0262 0.0813 0.0813
Brugia malayi nuclear receptor NHR-88 0.0082 0.0218 0.0218
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0094 0.0256 0.0256
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0059 0.0142 0.0142
Schistosoma mansoni hypothetical protein 0.002 0.0014 0.0014
Brugia malayi RNA, U transporter 1 0.0084 0.0226 0.0226
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.002 0.0013 0.0013
Loa Loa (eye worm) steroid hormone receptor 0.0082 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0066 0.0671
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.003 0.0092
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0042 0.0085 0.0134
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0093 0.0941
Echinococcus granulosus zinc finger protein 0.2779 0.9134 0.9134
Brugia malayi orphan nuclear receptor NR2E1 0.0039 0.0075 0.0075
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0478 0.1526 0.1526
Onchocerca volvulus 0.0127 0.0367 0.1139
Loa Loa (eye worm) hypothetical protein 0.0262 0.0813 0.0813
Mycobacterium ulcerans lipase LipD 0.0296 0.0924 0.6525
Loa Loa (eye worm) hypothetical protein 0.1094 0.3563 0.3563
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0207 0.2546
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0024 0.0027 0.0279
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0003 0.0018
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.02 0.0606 0.6159
Loa Loa (eye worm) nuclear receptor NHR-67 0.0039 0.0075 0.0075
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0026 0.0082
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0042 0.0085 0.0586
Trypanosoma brucei hypothetical protein, conserved 0.0296 0.0924 0.9382
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0024 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0106
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.002 0.0013 0.0013
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0082 0.0218 0.0218
Treponema pallidum alginate O-acetylation protein (algI) 0.0262 0.0813 1
Giardia lamblia Kinase, CMGC MAPK 0.0111 0.0314 0.1435
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0045 0.0318
Loa Loa (eye worm) hypothetical protein 0.0262 0.0813 0.0813
Echinococcus multilocularis snurportin 1 0.0317 0.0995 0.0995
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0039 0.0075 0.0075
Leishmania major hypothetical protein, conserved 0.0296 0.0924 0.6531
Trichomonas vaginalis Sentrin-specific protease, putative 0.0025 0.003 0.0092
Mycobacterium tuberculosis Probable dehydrogenase 0.0111 0.0314 0.0504
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0314 0.0973
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0075 0.0075
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0003 0.0026
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0024 0.0027 0.0177
Loa Loa (eye worm) hypothetical protein 0.0296 0.0924 0.0924
Loa Loa (eye worm) Ulp1 protease 0.0025 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0296 0.0924 0.0924
Brugia malayi MH2 domain containing protein 0.0124 0.0356 0.0356
Echinococcus granulosus Aminotransferase class III 0.0022 0.0018 0.0018
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0082 0.0218 0.0218
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.02 0.0606 0.0606
Trichomonas vaginalis transmembrane protein nessy, putative 0.0262 0.0813 0.2522
Plasmodium falciparum importin beta, putative 0.003 0.0045 0.0553
Chlamydia trachomatis deubiquitinase/deneddylase Dub1 0.0025 0.003 1
Echinococcus multilocularis muscleblind protein 0.1094 0.3563 0.3563
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0024 0.0027 0.0027
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.012 0.0343 0.0343
Onchocerca volvulus 0.002 0.0013 0.004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0127 0.0367 0.0367
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0024 0.0027 0.0177
Entamoeba histolytica hypothetical protein 0.0094 0.0256 0.1173
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0042 0.0085 0.0134
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0014 0.0014
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.002 0.0013 0.0013
Echinococcus granulosus importin subunit beta 1 0.003 0.0045 0.0045
Onchocerca volvulus 0.0039 0.0075 0.0232
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0151 0.0444 0.0444
Schistosoma mansoni ap endonuclease 0.0059 0.0142 0.0142
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0064 0.02
Entamoeba histolytica hypothetical protein 0.0024 0.0026 0.0121
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0086 0.0933
Brugia malayi Bromodomain containing protein 0.0045 0.0097 0.0097
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0054 0.0394
Giardia lamblia Alcohol dehydrogenase 0.0024 0.0027 0.0126
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0094 0.0256 0.2603
Brugia malayi MAP kinase sur-1 0.0111 0.0314 0.0314
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0042 0.0085 0.0586
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.0813 0.2522
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0064 0.0455
Entamoeba histolytica vacuolar protein sorting 26 0.0262 0.0813 0.3721
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0094 0.0256 0.2603
Loa Loa (eye worm) hypothetical protein 0.0262 0.0813 0.0813
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0042 0.0085 0.0586
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.003 0.0136
Mycobacterium tuberculosis Probable reductase 0.0111 0.0314 0.0504
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0296 0.0924 0.6525
Onchocerca volvulus 0.0042 0.0086 0.0267
Brugia malayi MBOAT family protein 0.0262 0.0813 0.0813
Leishmania major mitochondrial DNA polymerase beta 0.0314 0.0985 0.6961
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0082 0.0218 0.0218
Leishmania major glycerol uptake protein, putative 0.0262 0.0813 0.5748
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0034 0.0106
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.248 0.8145 0.8145
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0193 0.0584 0.2671
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0262 0.0813 0.5748
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0066 0.045
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0094 0.0256 0.1812
Echinococcus multilocularis zinc finger protein 0.2779 0.9134 0.9134
Brugia malayi Steroid receptor seven-up type 2 0.0082 0.0218 0.0218
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0042 0.0085 0.0586
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0041 0.0081 0.0081
Schistosoma mansoni hypothetical protein 0.0103 0.0287 0.0287
Mycobacterium tuberculosis Probable aminotransferase 0.0151 0.0447 0.0718
Brugia malayi ecdysteroid receptor 0.0082 0.0218 0.0218
Echinococcus granulosus geminin 0.0176 0.0528 0.0528
Echinococcus multilocularis lamin 0.0026 0.0034 0.0034
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0042 0.0085 0.0586
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0012 0.0126
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.002 0.0013 0.0013
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0082 0.0218 0.0218
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0477 0.0477
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0064 0.0654
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0024 0.0027 0.0279
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0022 0.0018 0.0025
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0039 0.0075 0.0075
Brugia malayi nuclear hormone receptor 0.0082 0.0218 0.0218
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.0188 0.0188
Toxoplasma gondii aldehyde dehydrogenase 0.0444 0.1415 1
Trichomonas vaginalis D-aminoacylase, putative 0.0296 0.0924 0.2866
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0064 0.02
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0042 0.0085 0.0586
Loa Loa (eye worm) hypothetical protein 0.0262 0.0813 0.0813
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0466 0.1488 0.1488
Loa Loa (eye worm) hypothetical protein 0.0026 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0043 0.009 0.009
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.02 0.0606 0.0606
Trichomonas vaginalis ran, putative 0.0022 0.0019 0.0059
Entamoeba histolytica G protein alpha subunit, putative 0.002 0.0013 0.0059
Trypanosoma brucei trypanothione reductase 0.0049 0.0108 0.1095
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0149 0.0149
Mycobacterium tuberculosis Conserved protein 0.0296 0.0924 0.1489
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.003 0.003
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0012 0.0012
Onchocerca volvulus Bile acid receptor homolog 0.0082 0.0218 0.0676
Brugia malayi glutathione reductase 0.0049 0.0108 0.0108
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0024 0.0027 0.0126
Echinococcus granulosus cytochrome P450 2K1 0.0042 0.0085 0.0085
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.002 0.0013 0.0013
Giardia lamblia Histone acetyltransferase GCN5 0.0084 0.0223 0.1021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0075 0.0075
Leishmania major DNA polymerase eta, putative 0.002 0.0012 0.0088
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0012 0.0126
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.02 0.0606 0.1881
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0075 0.0075
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0127 0.0367 0.2594
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0042 0.0085 0.0603
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0024 0.0027 0.0279
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0003 0.0027
Echinococcus granulosus histone acetyltransferase KAT2B 0.0094 0.0256 0.0256
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0024 0.0027 0.0279
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.002 0.0013 0.0013
Brugia malayi tailless protein 0.0039 0.0075 0.0075
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0059 0.0142 1
Plasmodium falciparum thioredoxin reductase 0.0017 0.0003 0.0031
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0024 0.0027 0.0279
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0262 0.0813 0.5748
Loa Loa (eye worm) cytochrome P450 family protein 0.0165 0.0491 0.0491
Loa Loa (eye worm) hypothetical protein 0.0043 0.009 0.009
Entamoeba histolytica hypothetical protein 0.0262 0.0813 0.3721
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0082 0.0218 0.0218
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0013 0.0013
Loa Loa (eye worm) cytochrome P450 0.0042 0.0085 0.0085
Leishmania major trypanothione reductase 0.0049 0.0108 0.0762
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.3041 1 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0111 0.0314 0.0504
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0025 0.003 0.003
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0024 0.0027 0.0177
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.003 0.0092
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0013
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0059 0.0142 0.1444
Echinococcus granulosus dual specificity 0.0094 0.0256 0.0256
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0017 0.0017
Echinococcus granulosus sentrin specific protease 7 0.0025 0.003 0.003
Schistosoma mansoni nuclear receptor 0.0039 0.0075 0.0075
Onchocerca volvulus 0.0296 0.0924 0.2866
Brugia malayi Cytochrome P450 family protein 0.0042 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.1094 0.3563 0.3563
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Leishmania major cytochrome p450-like protein 0.0061 0.0149 0.1051
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0314 0.0973
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0064 0.0654
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.02 0.0606 0.0606
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0003 0.0018
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0002 0.0002
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0262 0.0813 0.3721
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0287 0.0287
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0063 0.0063
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0026 0.0268
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0104 0.0104
Loa Loa (eye worm) hhat protein 0.0262 0.0813 0.0813
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0082 0.0218 0.0218
Schistosoma mansoni inositol monophosphatase 0.0036 0.0066 0.0066
Trypanosoma cruzi glycerol uptake protein, putative 0.0262 0.0813 0.8257
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0082 0.0218 0.0218
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0104 0.0104
Echinococcus granulosus sentrin specific protease 1 0.0091 0.0247 0.0247
Brugia malayi hypothetical protein 0.0042 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0043 0.009 0.009
Schistosoma mansoni trimeric G-protein alpha o subunit 0.002 0.0013 0.0013
Loa Loa (eye worm) nuclear hormone receptor 0.0039 0.0075 0.0075
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0042 0.0085 0.0866
Brugia malayi acetyltransferase, GNAT family protein 0.0313 0.098 0.098
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0024 0.0027 0.0126
Echinococcus multilocularis microtubule associated protein 2 0.1463 0.4782 0.4782
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0003 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0127 0.0367 0.0367
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0066 0.0205
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0042 0.0085 0.0586
Loa Loa (eye worm) Ulp1 protease 0.0025 0.003 0.003
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0024 0.0027 0.0085
Loa Loa (eye worm) hypothetical protein 0.0103 0.0287 0.0287
Trichomonas vaginalis set domain proteins, putative 0.0991 0.3223 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.02 0.0606 0.0606
Schistosoma mansoni aldehyde dehydrogenase 0.0024 0.0027 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0082 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0094 0.0258 0.0258
Schistosoma mansoni peptidase 0.0018 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0082 0.0218 0.0218
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0042 0.0085 0.0134
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0003 0.0031
Brugia malayi Protein kinase domain containing protein 0.0094 0.0256 0.0256
Entamoeba histolytica protein kinase, putative 0.0094 0.0256 0.1173
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0042 0.0085 0.0134
Schistosoma mansoni hypothetical protein 0.0042 0.0086 0.0086
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0042 0.0085 0.0586
Echinococcus granulosus survival motor neuron protein 1 0.0496 0.1587 0.1587
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0034 0.0106
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0064 0.02
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.002 0.0013 0.004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0002 0.0002
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0063 0.0063
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0082 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0253 0.0782 0.0782
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0034 0.0106
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0064 0.0295
Echinococcus multilocularis dna polymerase eta 0.002 0.0012 0.0012
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0151 0.0447 0.4734
Loa Loa (eye worm) hypothetical protein 0.0296 0.0924 0.0924
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0042 0.0086 0.0267
Leishmania major importin beta-1 subunit, putative 0.0024 0.0026 0.0186
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0075 0.0232
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0042 0.0085 0.0134
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0012 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0106
Loa Loa (eye worm) hypothetical protein 0.0151 0.0444 0.0444
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0012 0.0012
Schistosoma mansoni intermediate filament proteins 0.0026 0.0034 0.0034
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0466 0.1488 0.1488
Echinococcus granulosus cpg binding protein 0.0125 0.0361 0.0361
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0111 0.0314 0.0504
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0012 0.0126
Schistosoma mansoni coup transcription factor 0.0082 0.0218 0.0218
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.0149 0.0149
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0042 0.0085 0.0134
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0012 0.0039
Loa Loa (eye worm) hypothetical protein 0.007 0.0177 0.0177
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0012 0.0126
Treponema pallidum exodeoxyribonuclease (exoA) 0.0059 0.0142 0.1723
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.001
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0111 0.0314 0.2217
Brugia malayi hypothetical protein 0.0042 0.0086 0.0086
Brugia malayi Bromodomain containing protein 0.0088 0.0238 0.0238
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0086 0.0086
Echinococcus granulosus lamin dm0 0.0026 0.0034 0.0034
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0477 0.0477
Onchocerca volvulus 0.0093 0.0253 0.0786
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0124 0.0355 0.057
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0019 0.0193
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0082 0.0218 0.0218
Brugia malayi cytochrome P450 0.0042 0.0085 0.0085
Onchocerca volvulus 0.0101 0.0281 0.0873
Echinococcus granulosus histone lysine methyltransferase setb 0.0144 0.0423 0.0423
Brugia malayi F/Y-rich N-terminus family protein 0.0042 0.0086 0.0086
Echinococcus multilocularis nuclear receptor nhr 48 0.0039 0.0075 0.0075
Echinococcus granulosus dna polymerase kappa 0.002 0.0012 0.0012
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0075 0.0075
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0066 0.0066
Loa Loa (eye worm) G protein alpha subunit 3 0.002 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0043 0.009 0.009
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0066 0.0467
Echinococcus granulosus dna polymerase eta 0.002 0.0012 0.0012
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0003 0.0018
Brugia malayi hypothetical protein 0.0039 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0042 0.0086 0.0086
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0314 0.0973
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0262 0.0813 0.0813
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0022 0.0018 0.0025
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0262 0.0813 0.0813
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0106
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0082 0.0218 0.0218
Echinococcus granulosus neuropeptide receptor A26 0.099 0.3219 0.3219
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0466 0.1488 0.1488
Mycobacterium leprae Probable lipase LipE 0.0296 0.0924 1
Leishmania major cytochrome p450-like protein 0.0042 0.0085 0.0603
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0012 0.007
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0003 0.0026
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.002 0.0013 0.004
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0019 0.0019
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0039 0.0075 0.0075
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0025 0.003 0.0302
Loa Loa (eye worm) hypothetical protein 0.0092 0.0251 0.0251
Echinococcus granulosus lamin 0.0026 0.0034 0.0034
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.0356 0.0356
Brugia malayi nuclear receptor RXR 0.0043 0.009 0.009
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0042 0.0085 0.0586
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0075 0.0232
Loa Loa (eye worm) hypothetical protein 0.0296 0.0924 0.0924
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0111 0.0314 0.0504
Schistosoma mansoni aldehyde dehydrogenase 0.0024 0.0027 0.0027
Toxoplasma gondii LsmAD domain-containing protein 0.0079 0.0207 0.1463
Plasmodium falciparum sentrin-specific protease 1 0.0091 0.0247 0.3034
Echinococcus multilocularis zinc finger protein 0.0034 0.0058 0.0058
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0127 0.0367 0.0367
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0125 0.1265

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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