Detailed information for compound 107663

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 438.43 | Formula: C23H22N2O7
  • H donors: 1 H acceptors: 6 LogP: 2.98 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCc1c(OC(=O)C)c2cccnc2n(c1=O)c1ccc(c(c1)C(=O)O)OC(=O)C
  • InChi: 1S/C23H22N2O7/c1-4-5-7-17-20(32-14(3)27)16-8-6-11-24-21(16)25(22(17)28)15-9-10-19(31-13(2)26)18(12-15)23(29)30/h6,8-12H,4-5,7H2,1-3H3,(H,29,30)
  • InChiKey: BVRJTHYSGHBUEB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis importin beta-1, putative 0.0019 0.0086 0.0238
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Echinococcus multilocularis transcription factor Dp 1 0.0015 0.006 0.0059
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0008 0.0008 0.0199
Brugia malayi Pre-SET motif family protein 0.0078 0.0495 0.0494
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0015 0.0063 0.0062
Plasmodium vivax serine-repeat antigen (SERA) 0.0111 0.0724 0.3587
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0048 0.0125
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0016 0.0067 0.092
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0048 0.013
Trypanosoma brucei cytochrome P450, putative 0.0052 0.0315 0.0869
Entamoeba histolytica cysteine protease, putative 0.0113 0.0739 0.3664
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0009 0.002 0.0055
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.003 0.0163 0.016
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0028 0.0152 0.015
Leishmania major cytochrome p450-like protein 0.0052 0.0315 0.0869
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0103 0.0668 0.0667
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0021 0.0103 0.1431
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0063 0.039 0.1917
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0008 0.0008 0.0005
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0036 0.0208 0.0207
Schistosoma mansoni nAChR subunit 0.0079 0.0502 0.05
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0021 0.0103 0.2642
Loa Loa (eye worm) hypoxia-induced factor 1 0.0096 0.0622 0.0621
Onchocerca volvulus 0.0296 0.2004 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0047 0.0278 0.6969
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0085 0.0542 0.0541
Schistosoma mansoni nAChR subunit 0.0079 0.0502 0.05
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0017 0.0074 0.1008
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0034 0.0031
Echinococcus multilocularis transfer RNA-Lys 0.0023 0.0115 0.0114
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0034 0.0191 0.019
Entamoeba histolytica cysteine protease, putative 0.0113 0.0739 0.3664
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0008 0.0008 0.0006
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0048 0.0289 0.0282
Trypanosoma cruzi DNA polymerase kappa, putative 0.0013 0.0048 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0315 0.2135 0.5941
Loa Loa (eye worm) hypothetical protein 0.0122 0.0801 0.0799
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0056 0.0346 0.0942
Leishmania major hypothetical protein, conserved 0.0008 0.0011 0.0024
Echinococcus multilocularis heat shock protein 90 0.0052 0.0315 0.0314
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Brugia malayi N-terminal motif family protein 0.0008 0.0008 0.0006
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0525 0.3593 0.3591
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0076 0.0483 0.0476
Brugia malayi cathepsin L-like precursor 0.0293 0.1989 0.1988
Trypanosoma brucei heat shock protein 90, putative 0.0052 0.0315 0.087
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0013 0.0042 0.0041
Mycobacterium ulcerans aldehyde dehydrogenase 0.0047 0.0278 0.3934
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.003 0.0163 0.016
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0034 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0111 0.0724 0.2013
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0008 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0046
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0021 0.0103 0.1431
Brugia malayi Cation transporter family protein 0.0079 0.0502 0.0501
Trichomonas vaginalis heat shock protein, putative 0.0044 0.0259 0.072
Echinococcus granulosus lipoxygenase domain containing protein 0.0035 0.0197 0.0195
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0008 0.0008 0.0001
Brugia malayi cytosol aminopeptidase 0.0013 0.0042 0.0041
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0018 0.008 0.1876
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0047 0.0278 0.0277
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0111 0.0724 0.3586
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.145 1 1
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0079 0.0502 0.05
Loa Loa (eye worm) hypothetical protein 0.0027 0.0142 0.014
Echinococcus granulosus leucine aminopeptidase protein 0.0063 0.039 0.0389
Leishmania major hypothetical protein, unknown function 0.0008 0.0008 0.0014
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0017 0.0074 0.1008
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Echinococcus multilocularis ecdysone induced protein 78C 0.0103 0.0668 0.0667
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0008 0.0008 0.0005
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0136 0.0901 0.09
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0079 0.0506 0.0505
Echinococcus multilocularis cathepsin L 0.0113 0.0739 0.0738
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0248 0.1673 0.1672
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0009 0.002 0.0055
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0036 0.0208 0.0207
Mycobacterium ulcerans two component sensor kinase MprB 0.001 0.0024 0.0293
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0019 0.0088 0.2215
Schistosoma mansoni netrin receptor unc5 0.0009 0.0015 0.0012
Leishmania major protein kinase, putative 0.0009 0.0017 0.0038
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0079 0.0502 0.0501
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0054 0.0332 0.0331
Giardia lamblia Histone acetyltransferase GCN5 0.0013 0.0047 0.0123
Schistosoma mansoni hypothetical protein 0.0041 0.0237 0.0234
Mycobacterium ulcerans polyketide synthase 0.0021 0.0103 0.1431
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0724 0.2013
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.001 0.0024 0.0293
Mycobacterium leprae Conserved hypothetical protein 0.0017 0.0074 0.1884
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0079 0.0502 0.0501
Mycobacterium leprae conserved hypothetical protein 0.001 0.0025 0.0642
Brugia malayi Papain family cysteine protease containing protein 0.0111 0.0724 0.0723
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0017 0.0074 0.0197
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0008 0.0008 0.0005
Schistosoma mansoni heat shock protein 0.0052 0.0315 0.0312
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0012 0.0035 0.0032
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0008 0.0008 0.007
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0011 0.0034 0.0092
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.001 0.0024 0.0023
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.0292 0.0291
Loa Loa (eye worm) hypothetical protein 0.0023 0.0117 0.0115
Echinococcus multilocularis Protein lozenge 0.0021 0.0101 0.01
Onchocerca volvulus 0.0079 0.0502 0.2478
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0111 0.0724 0.2013
Loa Loa (eye worm) hypothetical protein 0.0035 0.0197 0.0195
Mycobacterium tuberculosis Conserved protein 0.0008 0.0008 0.0194
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0111 0.0724 0.3587
Mycobacterium ulcerans Type I modular polyketide synthase 0.002 0.0095 0.1308
Schistosoma mansoni cathepsin B (C01 family) 0.0111 0.0724 0.0721
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.001 0.0025 0.0315
Brugia malayi Doublecortin family protein 0.0035 0.0197 0.0195
Giardia lamblia Cathepsin B precursor 0.0525 0.3593 1
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0043 0.025 0.0249
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0074 0.0066
Schistosoma mansoni zinc finger protein 0.0049 0.0292 0.0289
Brugia malayi Cation transporter family protein 0.0122 0.0801 0.0799
Onchocerca volvulus Bile acid receptor homolog 0.0103 0.0668 0.3309
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0113 0.0739 0.0737
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0017 0.0074 0.1842
Loa Loa (eye worm) hypothetical protein 0.0034 0.0192 0.0191
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0111 0.0724 0.0721
Loa Loa (eye worm) fibroinase 0.0296 0.2004 0.2003
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0007 0.0003 0.0078
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0043 0.025 0.0247
Loa Loa (eye worm) ctsf protein 0.0296 0.2004 0.2003
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0008 0.0008 0.007
Loa Loa (eye worm) hypothetical protein 0.0035 0.0198 0.0197
Schistosoma mansoni ap endonuclease 0.0019 0.0087 0.0084
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0312 0.212 0.2114
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0103 0.0668 0.0667
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.001 0.0024 0.0303
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0094 0.061 0.1696
Trypanosoma cruzi cytochrome P450, putative 0.0052 0.0315 0.0307
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.007 0.0067
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0034 0.0191 0.4794
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0038 0.0218 0.5453
Trypanosoma brucei heat shock protein, putative 0.0052 0.0315 0.087
Plasmodium falciparum serine repeat antigen 5 0.0111 0.0724 0.3587
Schistosoma mansoni coup transcription factor 0.0103 0.0668 0.0666
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0147 0.0146
Mycobacterium ulcerans polyketide synthase Pks13 0.003 0.0163 0.229
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0057 0.035 0.0349
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0008 0.0008 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0048 0.0125
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0034 0.0033
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0048 0.0289 0.7396
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0103 0.0668 0.0667
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0111 0.0724 0.0723
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0739 0.2056
Giardia lamblia Cysteine protease 0.0111 0.0724 0.2009
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0056 0.0346 0.0344
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0057 0.035 0.0349
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0103 0.0668 0.0666
Echinococcus granulosus cathepsin b 0.145 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0724 0.2013
Plasmodium falciparum histone acetyltransferase GCN5 0.0013 0.0047 0.0196
Brugia malayi conserved hypotetical protein 0.0049 0.0292 0.0291
Echinococcus multilocularis snurportin 1 0.0248 0.1673 0.1672
Echinococcus granulosus cathepsin b 0.145 1 1
Entamoeba histolytica cysteine protease, putative 0.0113 0.0739 0.3664
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0048 0.0289 0.7231
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0008 0.0008 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0293 0.1989 0.5535
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0008 0.0011 0.0029
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0017 0.0074 0.1008
Echinococcus granulosus GTP binding nuclear protein Ran 0.0017 0.0074 0.0073
Brugia malayi Cathepsin L-like precursor 0.0296 0.2004 0.2003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0103 0.0668 0.0667
Schistosoma mansoni hypothetical protein 0.0256 0.1727 0.1725
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0056 0.0346 0.0345
Onchocerca volvulus 0.0296 0.2004 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0111 0.0724 0.3586
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0046 0.0275 0.7051
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0057 0.035 0.0349
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0122 0.0801 0.08
Onchocerca volvulus 0.0167 0.1112 0.5533
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0724 0.2013
Echinococcus granulosus heat shock protein 0.0052 0.0315 0.0314
Schistosoma mansoni lipoxygenase 0.0122 0.0802 0.0799
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0071 0.0316
Mycobacterium leprae Probable two-component sensor kinase 0.0008 0.0011 0.0289
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0056 0.0346 0.0955
Plasmodium vivax DNA gyrase subunit B, putative 0.0008 0.0011 0.0018
Giardia lamblia Cathepsin B precursor 0.0111 0.0724 0.2009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0724 0.2013
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0011 0.0034 0.0033
Brugia malayi isocitrate dehydrogenase 0.0017 0.0071 0.0069
Onchocerca volvulus 0.0036 0.0208 0.1002
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0292 0.0289
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0079 0.0502 0.0501
Brugia malayi follicle stimulating hormone receptor 0.0073 0.0459 0.0458
Brugia malayi Nuclear hormone receptor E75 0.0049 0.0292 0.0291
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Onchocerca volvulus 0.0049 0.0292 0.1423
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0017 0.0074 0.1008
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0122 0.0801 0.0799
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0074 0.0072
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0017 0.0074 0.1842
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0034 0.0191 0.4794
Loa Loa (eye worm) hypothetical protein 0.0178 0.1188 0.1187
Echinococcus multilocularis leucyl aminopeptidase 0.0013 0.0042 0.0041
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0011 0.0018
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.001 0.0024 0.0407
Giardia lamblia Cathepsin L precursor 0.0111 0.0724 0.2009
Schistosoma mansoni glutamate receptor NMDA 0.0053 0.0321 0.0318
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0071 0.0069
Mycobacterium ulcerans leucyl aminopeptidase 0.0063 0.039 0.5536
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0087 0.0085
Trypanosoma brucei heat shock protein, putative 0.0052 0.0315 0.087
Plasmodium vivax importin-beta 2, putative 0.0023 0.0117 0.0545
Trypanosoma cruzi oligopeptidase b 0.0013 0.0048 0.004
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0017 0.0074 0.1842
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Schistosoma mansoni lozenge 0.0021 0.0101 0.0098
Brugia malayi nuclear receptor RXR 0.0049 0.0292 0.0291
Brugia malayi Cytochrome P450 family protein 0.0052 0.0315 0.0314
Brugia malayi bHLH-PAS transcription factor 0.0023 0.0115 0.0114
Brugia malayi heat shock protein 90 0.0052 0.0315 0.0314
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0076 0.0483 0.048
Toxoplasma gondii cathepsin CPC1 0.0111 0.0724 0.1998
Mycobacterium tuberculosis Probable peptidase 0.0013 0.0048 0.119
Plasmodium falciparum serine repeat antigen 8 0.0111 0.0724 0.3587
Brugia malayi beta-lactamase family protein 0.001 0.0025 0.0024
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0103 0.0668 0.0667
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0076 0.0483 0.0482
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0008 0.0008 0.0005
Mycobacterium tuberculosis Probable reductase 0.0034 0.0191 0.4794
Schistosoma mansoni cathepsin S (C01 family) 0.0111 0.0724 0.0721
Onchocerca volvulus 0.0018 0.008 0.0362
Loa Loa (eye worm) hypothetical protein 0.0111 0.0724 0.0723
Plasmodium falciparum serine repeat antigen 6 0.0111 0.0724 0.3587
Trypanosoma brucei protein kinase A regulatory subunit 0.0008 0.0008 0.0014
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0016 0.0069 0.1733
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0048 0.0125
Loa Loa (eye worm) hypothetical protein 0.0049 0.0298 0.0297
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0008 0.0008 0.0005
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0071 0.0189
Leishmania major DNA topoisomerase ii 0.0008 0.0011 0.0024
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0063 0.039 0.0383
Echinococcus granulosus carbonic anhydrase II 0.0076 0.0483 0.0482
Brugia malayi hypothetical protein 0.0104 0.0678 0.0677
Toxoplasma gondii hypothetical protein 0.0013 0.0048 0.0111
Echinococcus multilocularis aryl hydrocarbon receptor 0.0008 0.0012 0.001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0071 0.007
Giardia lamblia Cathepsin L precursor 0.0111 0.0724 0.2009
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0046
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0087 0.0396
Brugia malayi Cation transporter family protein 0.0079 0.0502 0.0501
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0034 0.0031
Schistosoma mansoni hypothetical protein 0.0028 0.0152 0.0149
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.001
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0013 0.0042 0.0041
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0034 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0017 0.0074 0.1842
Plasmodium vivax ataxin-2 like protein, putative 0.0022 0.0109 0.0507
Echinococcus granulosus survival motor neuron protein 1 0.0093 0.0602 0.0601
Plasmodium falciparum DNA gyrase subunit B 0.0008 0.0011 0.0018
Brugia malayi kinase, mitochondrial precursor 0.0008 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0056 0.0346 0.0344
Mycobacterium tuberculosis Conserved protein 0.001 0.0025 0.0627
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0017 0.0074 0.1008
Trichomonas vaginalis guanylate cyclase, putative 0.0009 0.002 0.0055
Schistosoma mansoni voltage-gated potassium channel 0.0009 0.0018 0.0015
Plasmodium vivax glutathione reductase, putative 0.0015 0.0059 0.0257
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0502 0.0499
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0048 0.0199
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0013 0.001
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0111 0.0724 0.3587
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0008 0.0008 0.0001
Loa Loa (eye worm) hypothetical protein 0.0111 0.0724 0.0723
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0049 0.0292 0.0289
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0094 0.061 0.1696
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Echinococcus granulosus death domain containing protein 0.0009 0.0015 0.0014
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0008 0.0012 0.001
Entamoeba histolytica hypothetical protein 0.0111 0.0724 0.3586
Echinococcus multilocularis cathepsin L cysteine protease 0.0296 0.2004 0.2003
Brugia malayi intermediate filament protein 0.0014 0.0054 0.0053
Entamoeba histolytica DNA topoisomerase II, putative 0.0008 0.0011 0.0017
Plasmodium vivax endoplasmin, putative 0.0052 0.0315 0.1539
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0013 0.0048 0.004
Brugia malayi prolyl oligopeptidase family protein 0.0056 0.0346 0.0344
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0013 0.0047 0.0635
Trypanosoma cruzi oligopeptidase b 0.0013 0.0048 0.004
Schistosoma mansoni cathepsin C 0.0111 0.0724 0.0721
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0008 0.0008 0.0014
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0008 0.0011 0.0059
Chlamydia trachomatis glutamine binding protein 0.0011 0.0033 0.0655
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0002
Leishmania major mitochondrial DNA topoisomerase II 0.0008 0.0011 0.0024
Brugia malayi CXXC zinc finger family protein 0.0018 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0008 0.0008 0.0194
Loa Loa (eye worm) hypothetical protein 0.0111 0.0724 0.0723
Echinococcus multilocularis endoplasmin 0.0048 0.0289 0.0288
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0009 0.0017 0.0009
Loa Loa (eye worm) hypothetical protein 0.0054 0.0332 0.0331
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.003 0.0163 0.4088
Leishmania major hypothetical protein, conserved 0.0022 0.0109 0.0296
Schistosoma mansoni survival motor neuron protein 0.0019 0.0087 0.0084
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.002 0.0095 0.2367
Onchocerca volvulus 0.0079 0.0502 0.2478
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0296 0.2004 0.5578
Leishmania major cathepsin L-like protease 0.0315 0.2135 0.5941
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0373 0.2537 0.2536
Echinococcus granulosus dna polymerase kappa 0.0013 0.0048 0.0046
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0017 0.0074 0.1842
Schistosoma mansoni hypothetical protein 0.001 0.0024 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0013 0.001
Leishmania major mitochondrial DNA polymerase beta 0.0102 0.066 0.1832
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.002 0.0095 0.2367
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0008 0.002
Echinococcus granulosus cathepsin L cysteine protease 0.0113 0.0739 0.0738
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0013 0.0048 0.013
Mycobacterium ulcerans thioesterase TesA 0.0017 0.0071 0.0977
Giardia lamblia Cathepsin L-like protease 0.0111 0.0724 0.2009
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0525 0.3593 1
Onchocerca volvulus 0.0035 0.0198 0.0952
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0008 0.0011 0.001
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.005 0.0302 0.03
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0043 0.025 0.0247
Brugia malayi Latrophilin receptor protein 2 0.0056 0.0346 0.0344
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0111 0.0724 0.3587
Trypanosoma cruzi importin beta-1 subunit, putative 0.0019 0.0086 0.0078
Schistosoma mansoni hypothetical protein 0.0526 0.36 0.3598
Echinococcus granulosus beta LACTamase domain containing family member 0.001 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Brugia malayi Papain family cysteine protease containing protein 0.0296 0.2004 0.2003
Trichomonas vaginalis bromodomain-containing protein, putative 0.0014 0.0055 0.0151
Onchocerca volvulus 0.0079 0.0502 0.2478
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0008 0.0011 0.0018
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0026 0.0136 0.0135
Leishmania major cyclic nucleotide-binding protein-like protein 0.0008 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0076 0.0483 0.048
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.001 0.0024 0.0607
Schistosoma mansoni glutaminase 0.0108 0.0703 0.07
Trichomonas vaginalis esterase, putative 0.001 0.0025 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0103 0.0668 0.0667
Loa Loa (eye worm) ACC-1 protein 0.0079 0.0502 0.0501
Mycobacterium ulcerans hypothetical protein 0.001 0.0025 0.0315
Echinococcus granulosus prolyl endopeptidase 0.0013 0.0048 0.0046
Echinococcus granulosus microtubule associated protein 2 0.029 0.1965 0.1964
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0315 0.0875
Brugia malayi Steroid receptor seven-up type 2 0.0103 0.0668 0.0667
Schistosoma mansoni ran 0.0017 0.0074 0.0071
Echinococcus granulosus glycine receptor subunit beta 0.0122 0.0801 0.08
Brugia malayi hypothetical protein 0.0036 0.0208 0.0207
Trichomonas vaginalis CMGC family protein kinase 0.0079 0.0502 0.1396
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.001 0.0024 0.059
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0049 0.0292 0.0291
Giardia lamblia Encystation-specific protease 0.0111 0.0724 0.2009
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0011 0.0028 0.0077
Schistosoma mansoni hypothetical protein 0.0136 0.0901 0.0898
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0087 0.024
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0088 0.0087
Entamoeba histolytica cysteine protease, putative 0.0113 0.0739 0.3664
Echinococcus multilocularis dna polymerase kappa 0.0013 0.0048 0.0046
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0012 0.0035 0.0077
Trypanosoma brucei heat shock protein, putative 0.0052 0.0315 0.087
Giardia lamblia Cathepsin L precursor 0.0111 0.0724 0.2009
Echinococcus multilocularis survival motor neuron protein 1 0.0093 0.0602 0.0601
Echinococcus multilocularis prolyl endopeptidase 0.0013 0.0048 0.0046
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0079 0.0502 0.1391
Entamoeba histolytica cysteine protease, putative 0.0111 0.0724 0.3586
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.003 0.0163 0.0162
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0009 0.0015 0.0014
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0103 0.0668 0.0667
Trypanosoma cruzi cysteine peptidase, putative 0.0315 0.2135 0.2129
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0111 0.0724 0.0721
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Loa Loa (eye worm) hypothetical protein 0.0028 0.0152 0.015
Brugia malayi fibroinase precursor 0.0111 0.0724 0.0723
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0008 0.0008 0.0006
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.0292 0.1423
Plasmodium falciparum ataxin-2 like protein, putative 0.0022 0.0109 0.0507
Echinococcus multilocularis mitogen activated protein kinase 3 0.0079 0.0502 0.0501
Plasmodium vivax heat shock protein 86, putative 0.0052 0.0315 0.1539
Echinococcus multilocularis GPCR, family 2 0.0056 0.0346 0.0345
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0038 0.0219 0.0218
Loa Loa (eye worm) acyl carrier protein 0.0009 0.0019 0.0018
Brugia malayi Hsp90 protein 0.0034 0.0191 0.019
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0071 0.0316
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0296 0.2004 0.2003
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.002 0.0095 0.2421
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0111 0.0724 0.3587
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0315 0.0314
Mycobacterium leprae conserved hypothetical protein 0.0008 0.0008 0.0204
Trypanosoma cruzi cysteine proteinase, putative 0.0113 0.0739 0.0732
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0049 0.0292 0.0291
Loa Loa (eye worm) hypothetical protein 0.0103 0.0668 0.0667
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0008 0.0008 0.0006
Mycobacterium ulcerans transmembrane transport protein 0.0008 0.0008 0.0067
Echinococcus granulosus lamin 0.0014 0.0054 0.0053
Brugia malayi hypothetical protein 0.0049 0.0292 0.0291
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0019 0.0086 0.0238
Brugia malayi Death domain containing protein 0.0009 0.0015 0.0013
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Leishmania major regulatory subunit of protein kinase a-like protein 0.0008 0.0008 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0013 0.0048 0.004
Trypanosoma cruzi PAB1-binding protein , putative 0.0022 0.0109 0.0101
Brugia malayi Pre-SET motif family protein 0.0012 0.0035 0.0034
Brugia malayi bZIP transcription factor family protein 0.005 0.0302 0.03
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0049 0.0292 0.0291
Brugia malayi Cytochrome P450 family protein 0.0017 0.0074 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0315 0.2135 0.5941
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0056 0.0346 0.0955
Loa Loa (eye worm) thioredoxin reductase 0.0015 0.0059 0.0058
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0063 0.039 0.0383
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0079 0.0506 0.0505
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0724 0.2013
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.001 0.0025 0.0627
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0724 0.2013
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0087 0.0234
Echinococcus granulosus GPCR family 2 0.0056 0.0346 0.0345
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0087 0.2172
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0103 0.0668 0.0667
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0008 0.0011 0.0283
Loa Loa (eye worm) hypothetical protein 0.0103 0.0668 0.0667
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0111 0.0724 0.0723
Onchocerca volvulus 0.0008 0.0012 0.0019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Trypanosoma brucei heat shock protein, putative 0.0052 0.0315 0.087
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0167 0.1115 0.1114
Loa Loa (eye worm) heat shock protein 75 0.0034 0.0191 0.019
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0014 0.0055 0.0047
Leishmania major oligopeptidase b 0.0013 0.0048 0.0125
Trichomonas vaginalis heat shock protein, putative 0.0048 0.0289 0.0802
Brugia malayi glutaminase DH11.1 0.0108 0.0703 0.0701
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0063 0.039 0.108
Echinococcus multilocularis carbonic anhydrase 0.0028 0.0152 0.015
Loa Loa (eye worm) GABA receptor subunit 0.0086 0.0548 0.0547
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0034 0.0031
Echinococcus multilocularis voltage gated potassium channel 0.0017 0.007 0.0069
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0079 0.0502 0.0501
Schistosoma mansoni nAChR subunit 0.0079 0.0502 0.05
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0036 0.0208 0.0207
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0315 0.2135 0.5941
Echinococcus multilocularis cysteine protease 0.0296 0.2004 0.2003
Brugia malayi Importin beta-1 subunit 0.0023 0.0117 0.0115
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0019 0.009 0.2261
Brugia malayi Cathepsin L-like precursor 0.0296 0.2004 0.2003
Schistosoma mansoni transcription factor LCR-F1 0.0085 0.0542 0.054
Treponema pallidum heat shock protein 90 0.0048 0.0289 0.4666
Mycobacterium tuberculosis Probable hydrolase 0.001 0.0025 0.0627
Schistosoma mansoni nAChR subunit 0.0036 0.0208 0.0205
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0076 0.0483 0.0476
Trypanosoma cruzi Heat shock protein 83, putative 0.0052 0.0315 0.0307
Leishmania major cathepsin L-like protease 0.0296 0.2004 0.5575
Schistosoma mansoni nAChR subunit 0.0079 0.0502 0.05
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.001 0.0024 0.0293
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0034 0.0033
Onchocerca volvulus Cathepsin L homolog 0.0296 0.2004 1
Echinococcus granulosus cathepsin L 0.0111 0.0724 0.0723
Onchocerca volvulus 0.0079 0.0502 0.2478
Trypanosoma brucei hypothetical protein, conserved 0.0008 0.0008 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0103 0.0668 0.0667
Entamoeba histolytica cysteine proteinase, putative 0.0296 0.2004 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0009 0.002 0.0055
Trypanosoma brucei oligopeptidase b 0.0013 0.0048 0.0125
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0111 0.0724 0.3587
Onchocerca volvulus 0.0111 0.0724 0.3587
Mycobacterium ulcerans polyketide synthase 0.002 0.0095 0.1308
Plasmodium vivax SET domain protein, putative 0.0012 0.0035 0.0138
Brugia malayi polk-prov protein 0.001 0.0025 0.0024
Onchocerca volvulus 0.001 0.0025 0.0087
Brugia malayi nuclear hormone receptor 0.0049 0.0292 0.0291
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0017 0.007 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0315 0.2135 0.5941
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Mycobacterium leprae Polyketide synthase Pks13 0.003 0.0163 0.4181
Brugia malayi beta-lactamase family protein 0.001 0.0025 0.0024
Toxoplasma gondii heat shock protein 90, putative 0.0052 0.0315 0.0857
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0017 0.0071 0.1828
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0017 0.0074 0.0073
Trichomonas vaginalis DNA topoisomerase II, putative 0.0008 0.0011 0.0029
Echinococcus multilocularis RUN 0.0035 0.0197 0.0195
Trypanosoma cruzi heat shock protein 90, putative 0.0052 0.0315 0.0307
Trichomonas vaginalis heat shock protein, putative 0.003 0.0162 0.0449
Echinococcus granulosus cathepsin L cysteine proteinase 0.0296 0.2004 0.2003
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0048 0.0125
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0017 0.0074 0.1008
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0008 0.0008 0.0007
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0087 0.0086
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0122 0.0802 0.0801
Echinococcus granulosus snurportin 1 0.0248 0.1673 0.1672
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0087 0.1312
Entamoeba histolytica hypothetical protein 0.0085 0.0542 0.2677
Loa Loa (eye worm) glutathione reductase 0.0015 0.0059 0.0058
Entamoeba histolytica acetyltransferase, GNAT family 0.0013 0.0047 0.0195
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0034 0.0033
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.002 0.0095 0.2421
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0048 0.0125
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0011 0.0028 0.0077
Onchocerca volvulus 0.0036 0.0208 0.1002
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.001 0.0024 0.0293
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0012 0.003
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0011 0.0034 0.0033
Schistosoma mansoni nuclear hormone receptor 0.0103 0.0668 0.0666
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0014
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0079 0.0502 0.0501
Trichomonas vaginalis CMGC family protein kinase 0.0079 0.0502 0.1396
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0103 0.0668 0.0667
Toxoplasma gondii exonuclease III APE 0.0019 0.0087 0.022
Mycobacterium leprae putative cytochrome p450 0.0017 0.0074 0.1884
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0057 0.035 0.0349
Schistosoma mansoni hypothetical protein 0.0056 0.0346 0.0343
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0017 0.0074 0.0198
Plasmodium falciparum M17 leucyl aminopeptidase 0.0063 0.039 0.1917
Trypanosoma brucei hypothetical protein, conserved 0.001 0.0025 0.0062
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0071 0.0063
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0011 0.0034 0.0033
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0017 0.0074 0.1842
Entamoeba histolytica hypothetical protein 0.0085 0.0542 0.2677
Mycobacterium tuberculosis Conserved protein 0.001 0.0025 0.0627
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0167 0.1115 0.1114
Loa Loa (eye worm) nuclear hormone receptor 0.0049 0.0292 0.0291
Echinococcus multilocularis beta LACTamase domain containing family member 0.001 0.0025 0.0024
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0111 0.0724 0.0721
Mycobacterium tuberculosis Probable thioesterase TesA 0.0017 0.0071 0.1787
Toxoplasma gondii type I fatty acid synthase, putative 0.0014 0.0054 0.013
Onchocerca volvulus 0.0079 0.0502 0.2478
Mycobacterium tuberculosis Conserved hypothetical protein 0.0008 0.0008 0.0194
Echinococcus multilocularis carbonic anhydrase 0.0028 0.0152 0.015
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0111 0.0724 0.0721
Schistosoma mansoni cathepsin F (C01 family) 0.0293 0.1989 0.1986
Brugia malayi nuclear hormone receptor family member nhr-6 0.0049 0.0292 0.0291
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0017 0.0074 0.1842
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0094 0.061 0.1696
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0087 0.0086
Toxoplasma gondii aldehyde dehydrogenase 0.0047 0.0278 0.0755
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0048 0.0289 0.0797
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0013 0.0048 0.0045
Leishmania major protein kinase, putative 0.0016 0.0069 0.0184
Toxoplasma gondii DNA topoisomerase 2, putative 0.0008 0.0011 0.001
Brugia malayi Cathepsin L-like cysteine proteinase 0.0293 0.1989 0.1988
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0103 0.0668 0.0667
Echinococcus granulosus nuclear receptor nhr 48 0.0049 0.0292 0.0291
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0013 0.0042 0.011
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0525 0.3593 1
Schistosoma mansoni neurotransmitter gated ion channel 0.0043 0.025 0.0247
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0079 0.0502 0.0501
Trypanosoma cruzi PAB1-binding protein , putative 0.0022 0.0109 0.0101
Schistosoma mansoni hypothetical protein 0.0019 0.0087 0.0084
Mycobacterium ulcerans hypothetical protein 0.0008 0.0008 0.0067
Mycobacterium tuberculosis Probable two component sensor kinase 0.0008 0.0011 0.0283
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0079 0.0502 0.0501
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0103 0.0668 0.3309
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0008 0.002
Toxoplasma gondii cathepsin CPC2 0.0111 0.0724 0.1998
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0034 0.0033
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0008 0.0005
Plasmodium vivax unspecified product 0.0113 0.0739 0.3664
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0013 0.0046 0.0106
Schistosoma mansoni hypothetical protein 0.0526 0.36 0.3598
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0296 0.2004 0.5578
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0048 0.0289 0.0798
Echinococcus multilocularis musashi 0.0014 0.0054 0.0053
Trypanosoma cruzi cysteine peptidase, putative 0.0315 0.2135 0.2129
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0016 0.0067 0.1726
Mycobacterium ulcerans Type I modular polyketide synthase 0.002 0.0095 0.1308
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0008 0.0011 0.0283
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0017 0.0074 0.1008
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0044 0.0259 0.0258
Echinococcus granulosus cathepsin l cysteine peptidase 0.0296 0.2004 0.2003
Mycobacterium ulcerans transcriptional regulatory protein 0.0008 0.0008 0.0067
Onchocerca volvulus 0.0043 0.025 0.1214
Entamoeba histolytica heat shock protein 90, putative 0.0052 0.0315 0.1538
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0103 0.0668 0.0666
Loa Loa (eye worm) runx1 0.0021 0.0101 0.0099
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0094 0.061 0.1696
Schistosoma mansoni endoplasmin 0.0052 0.0315 0.0312
Trichomonas vaginalis penicillin-binding protein, putative 0.001 0.0025 0.0068
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Mycobacterium tuberculosis Two component sensor kinase MprB 0.001 0.0024 0.059
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0017 0.0074 0.1842
Entamoeba histolytica cysteine protease, putative 0.0113 0.0739 0.3664
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0026 0.0136 0.0128
Loa Loa (eye worm) ACC-1 protein 0.0079 0.0502 0.0501
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0008 0.0012 0.0004
Loa Loa (eye worm) CYP4Cod1 0.0052 0.0315 0.0314
Leishmania major trypanothione reductase 0.0015 0.0059 0.0157
Echinococcus granulosus cathepsin l1 0.0296 0.2004 0.2003
Plasmodium vivax hypothetical protein, conserved 0.001 0.0025 0.0087
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Entamoeba histolytica cysteine proteinase, putative 0.0113 0.0739 0.3664
Plasmodium falciparum thioredoxin reductase 0.0015 0.0059 0.0257
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0525 0.3593 0.3588
Loa Loa (eye worm) hypothetical protein 0.0035 0.0197 0.0195
Brugia malayi prolyl oligopeptidase family protein 0.0013 0.0048 0.0046
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0034 0.0031
Echinococcus multilocularis microtubule associated protein 2 0.029 0.1965 0.1964
Echinococcus multilocularis jun protein 0.005 0.0302 0.03
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0017 0.007 0.0069
Brugia malayi hypothetical protein 0.0085 0.0542 0.0541
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0008 0.0008 0.0005
Schistosoma mansoni cpg binding protein 0.0018 0.008 0.0077
Leishmania major cathepsin L-like protease 0.0296 0.2004 0.5575
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0078 0.0495 0.0494
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0111 0.0724 0.3587
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0296 0.2004 0.5578
Trypanosoma cruzi heat shock protein, putative 0.0034 0.0191 0.0184
Echinococcus granulosus cysteine protease 0.0113 0.0739 0.0738
Loa Loa (eye worm) hypothetical protein 0.0054 0.0332 0.0331
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0008 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0002
Trichomonas vaginalis sensor histidine kinase, putative 0.0011 0.0028 0.0077
Giardia lamblia Kinase, CMGC MAPK 0.0079 0.0502 0.1391
Brugia malayi nuclear hormone receptor family member odr-7 0.0049 0.0292 0.0291
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0079 0.0502 0.0501
Echinococcus multilocularis acylamino acid releasing enzyme 0.0013 0.0048 0.0046
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0008 0.0008 0.0007
Mycobacterium ulcerans beta-lactamase 0.001 0.0025 0.0315
Schistosoma mansoni thyroid hormone receptor 0.0239 0.1614 0.1611
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0013 0.0042 0.0035
Leishmania major cathepsin L-like protease 0.0296 0.2004 0.5575
Mycobacterium ulcerans Type I modular polyketide synthase 0.002 0.0095 0.1308
Echinococcus granulosus nmda type glutamate receptor 0.0062 0.0383 0.0382
Brugia malayi ecdysone receptor 0.0049 0.0292 0.0291
Plasmodium falciparum serine repeat antigen 7 0.0111 0.0724 0.3587
Brugia malayi nuclear hormone receptor 0.0103 0.0668 0.0667
Loa Loa (eye worm) LGC-31 protein 0.0079 0.0502 0.0501
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0079 0.0502 0.0501
Echinococcus multilocularis cathepsin b 0.145 1 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.025 0.0249
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0008 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0043 0.025 0.0249
Onchocerca volvulus 0.0039 0.0227 0.11
Schistosoma mansoni ap endonuclease 0.0019 0.0087 0.0084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0296 0.2004 0.5578
Echinococcus multilocularis lamin dm0 0.0014 0.0054 0.0053
Giardia lamblia Cathepsin L precursor 0.0111 0.0724 0.2009
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0013 0.0048 0.0111
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0026 0.0136 0.0371
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0017 0.0074 0.1008
Brugia malayi ecdysteroid receptor 0.0103 0.0668 0.0667
Onchocerca volvulus 0.0027 0.0142 0.0671
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.001 0.0024 0.0603
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0079 0.0502 0.0501
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0103 0.0668 0.0667
Loa Loa (eye worm) hypothetical protein 0.0111 0.0724 0.0723
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0122 0.0801 0.08
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0048 0.0125
Onchocerca volvulus 0.0296 0.2004 1
Entamoeba histolytica cysteine protease, putative 0.0113 0.0739 0.3664
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0087 0.0396
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0028 0.0152 0.015
Brugia malayi Endoplasmin precursor 0.0052 0.0315 0.0314
Loa Loa (eye worm) hypothetical protein 0.0011 0.0033 0.0032
Leishmania major cathepsin L-like protease 0.0296 0.2004 0.5575
Plasmodium falciparum endoplasmin, putative 0.0038 0.0218 0.1051
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Entamoeba histolytica cysteine protease, putative 0.0111 0.0724 0.3586
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0008 0.0011 0.001
Schistosoma mansoni lamin 0.0014 0.0054 0.0051
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0019 0.0088 0.0087
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0011 0.0029 0.0059
Trypanosoma cruzi cytochrome P450, putative 0.0052 0.0315 0.0307
Echinococcus multilocularis FTZ F1 alpha 0.0103 0.0668 0.0667
Leishmania major GTP-binding protein, putative 0.0017 0.0074 0.0198
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0071 0.007
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.003 0.0163 0.016
Mycobacterium ulcerans hypothetical protein 0.0008 0.0008 0.0067
Loa Loa (eye worm) hypothetical protein 0.0054 0.0332 0.0331
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0036 0.0208 0.0207
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0008 0.0008 0.0001
Loa Loa (eye worm) doublecortin family protein 0.0035 0.0197 0.0195
Schistosoma mansoni steroid hormone receptor ad4bp 0.0103 0.0668 0.0666
Plasmodium falciparum importin beta, putative 0.0023 0.0117 0.0545
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0315 0.2135 0.5941
Plasmodium falciparum DNA topoisomerase 2 0.0008 0.0011 0.0018
Chlamydia trachomatis DNA gyrase subunit B 0.0008 0.0011 0.0093
Onchocerca volvulus Cathepsin F homolog 0.0296 0.2004 1
Echinococcus granulosus Ankyrin 0.0009 0.0015 0.0014
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0036 0.0208 0.0206
Trypanosoma cruzi cysteine peptidase, putative 0.0113 0.0739 0.0732
Brugia malayi hypothetical protein 0.0036 0.0208 0.0207
Schistosoma mansoni heat shock protein 0.0052 0.0315 0.0312
Schistosoma mansoni retinoic acid receptor RXR 0.0103 0.0668 0.0666
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0008 0.0011 0.0087
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0008 0.0011 0.0004
Schistosoma mansoni cpg binding protein 0.0019 0.0087 0.0084
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0008 0.0013 0.0014
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.003 0.0163 0.016
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0008 0.0008 0.002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0047 0.0278 0.3934
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0017 0.0074 0.0073
Brugia malayi Cathepsin L-like precursor 0.0293 0.1989 0.1988
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0038 0.0222 0.0219
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0113 0.0739 0.0732
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0332 0.0331
Giardia lamblia Cysteine protease 0.0111 0.0724 0.2009
Schistosoma mansoni hypothetical protein 0.0008 0.0008 0.0005
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0013 0.0048 0.0045
Brugia malayi hypothetical protein 0.0043 0.0254 0.0252
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0111 0.0724 0.2009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0012 0.0035 0.0034
Brugia malayi Cathepsin L-like precursor 0.0296 0.2004 0.2003
Echinococcus granulosus glycine receptor subunit alpha 1 0.0122 0.0801 0.08
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0292 0.0291
Giardia lamblia Cathepsin B precursor 0.0111 0.0724 0.2009
Trichomonas vaginalis D-aminoacylase, putative 0.001 0.0025 0.0068
Loa Loa (eye worm) hypothetical protein 0.0167 0.1112 0.1111
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0017 0.0074 0.1842
Onchocerca volvulus 0.0103 0.0668 0.3309
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.002 0.0094 0.0091
Toxoplasma gondii hypothetical protein 0.0016 0.0069 0.0172
Loa Loa (eye worm) DR-78 0.0049 0.0292 0.0291
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0056 0.0346 0.0343
Onchocerca volvulus 0.0036 0.0208 0.1002
Mycobacterium ulcerans putative regultory protein 0.0008 0.0011 0.0118
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Brugia malayi Papain family cysteine protease containing protein 0.0113 0.0739 0.0738
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0017 0.0074 0.1008
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0017 0.0074 0.0332
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0013 0.0048 0.0636
Plasmodium falciparum cGMP-dependent protein kinase 0.0008 0.0013 0.0025
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0071 0.1773
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0008 0.0011 0.0024
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0087 0.0234
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0038 0.0218 0.5453
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0094 0.061 0.1696
Giardia lamblia Cathepsin B precursor 0.0525 0.3593 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0009 0.0015 0.0013
Onchocerca volvulus 0.0296 0.2004 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0122 0.0802 0.0801
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0024
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0111 0.0724 0.3587
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.001 0.0025 0.0627
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0315 0.2135 0.5941
Loa Loa (eye worm) hypothetical protein 0.0054 0.0332 0.0331
Onchocerca volvulus Putative nachr subunit 0.0079 0.0502 0.2478
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.145 1 1
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0079 0.0502 0.0501
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0008 0.0008 0.0007
Echinococcus granulosus cpg binding protein 0.0019 0.0087 0.0086
Trypanosoma cruzi heat shock protein 85, putative 0.0052 0.0315 0.0307
Echinococcus multilocularis heat shock protein 90 0.0044 0.0259 0.0258
Toxoplasma gondii cytochrome p450 superfamily protein 0.0017 0.0074 0.0184
Schistosoma mansoni endoplasmin 0.0052 0.0315 0.0312
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0013 0.001
Brugia malayi Thioredoxin reductase 0.0015 0.0059 0.0058
Loa Loa (eye worm) hypothetical protein 0.0103 0.0668 0.0667
Trypanosoma brucei DNA polymerase IV, putative 0.0013 0.0048 0.0125
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0102 0.066 0.0653
Trypanosoma cruzi trypanothione reductase, putative 0.0015 0.0059 0.0051
Brugia malayi Papain family cysteine protease containing protein 0.0111 0.0724 0.0723
Echinococcus multilocularis cathepsin L 0.0111 0.0724 0.0723
Echinococcus granulosus tumor protein p63 0.0239 0.1611 0.161
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) 0.0007 0.0003 0.0076
Mycobacterium ulcerans glutaminase 0.0108 0.0703 1
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.001 0.0024 0.0293
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0296 0.2004 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0076 0.0483 0.0482
Echinococcus granulosus single minded 2 0.0028 0.0151 0.015
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0026 0.0136 0.0135
Plasmodium vivax thioredoxin reductase, putative 0.0015 0.0059 0.0257
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0019 0.0086 0.0238
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0428 0.2919 0.2918
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0017 0.0074 0.0066
Trypanosoma brucei DNA polymerase IV, putative 0.0013 0.0048 0.0125
Echinococcus granulosus carbonic anhydrase 0.0028 0.0152 0.015
Trichomonas vaginalis D-aminoacylase, putative 0.001 0.0025 0.0068
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0017 0.0074 0.0073
Schistosoma mansoni thyroid hormone receptor 0.0239 0.1614 0.1611
Schistosoma mansoni pyruvate dehydrogenase 0.0008 0.0011 0.0008
Echinococcus granulosus Polycystic kidney disease protein 0.0035 0.0197 0.0195
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0024
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.002 0.0095 0.1308
Schistosoma mansoni importin beta-1 0.0023 0.0117 0.0114
Brugia malayi MAP kinase sur-1 0.0079 0.0502 0.0501
Echinococcus granulosus glycine receptor subunit beta 0.0122 0.0801 0.08
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0292 0.0289
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0054 0.0332 0.0329
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0019 0.009 0.2261
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0011 0.0033 0.0416
Mycobacterium tuberculosis Possible two component sensor kinase 0.0008 0.0011 0.0283
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0111 0.0724 0.0721
Toxoplasma gondii hypothetical protein 0.0028 0.0152 0.0401
Mycobacterium tuberculosis Probable sensor protein KdpD 0.001 0.0024 0.059
Brugia malayi PAS domain containing protein 0.0031 0.0171 0.017
Onchocerca volvulus 0.0035 0.0197 0.0946
Brugia malayi cytochrome P450 0.0017 0.0074 0.0072
Echinococcus multilocularis cathepsin L cysteine protease 0.0296 0.2004 0.2003
Brugia malayi hypothetical protein 0.0049 0.0292 0.0291
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0047 0.0278 0.0767
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0007 0.0003 0.0076
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0017 0.0074 0.1008
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0111 0.0724 0.0723
Brugia malayi Nuclear hormone receptor E75 0.0049 0.0292 0.0291
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Mycobacterium ulcerans hypothetical protein 0.0008 0.0008 0.0067
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0008 0.0011 0.001
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0103 0.0668 0.0667
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0011 0.0028 0.0535
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0079 0.0502 0.0501
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0103 0.0668 0.0667
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0012 0.003
Entamoeba histolytica hypothetical protein 0.0085 0.0542 0.2677
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0008 0.0011 0.0004
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0111 0.0724 0.0721
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Giardia lamblia Heat shock protein HSP 90-alpha 0.0044 0.0259 0.0714
Giardia lamblia Hypothetical protein 0.0111 0.0724 0.2009
Trypanosoma brucei DNA polymerase IV, putative 0.0011 0.0033 0.0084
Loa Loa (eye worm) hypothetical protein 0.0054 0.0332 0.0331
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0026 0.0136 0.0641
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0049 0.0294 0.0293
Giardia lamblia Cathepsin L precursor 0.0111 0.0724 0.2009
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.001 0.0025 0.0024
Entamoeba histolytica hypothetical protein, conserved 0.0013 0.0048 0.0198
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0012 0.0035 0.0034
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.001 0.0024 0.059
Loa Loa (eye worm) cytochrome P450 0.0017 0.0074 0.0072
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0014 0.0055 0.1387
Schistosoma mansoni neurotransmitter gated ion channel 0.0036 0.0208 0.0205
Mycobacterium ulcerans putative regulatory protein 0.0023 0.0115 0.1601
Schistosoma mansoni hypothetical protein 0.0056 0.0346 0.0343
Loa Loa (eye worm) acetylcholine receptor protein 0.0036 0.0208 0.0206
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0074 0.0066
Loa Loa (eye worm) hypothetical protein 0.0043 0.025 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0103 0.0668 0.0667
Schistosoma mansoni lamin 0.0014 0.0054 0.0051
Brugia malayi Melibiase family protein 0.002 0.0094 0.0093
Brugia malayi orphan nuclear receptor NR2E1 0.0049 0.0292 0.0291
Trichomonas vaginalis D-aminoacylase, putative 0.001 0.0025 0.0068
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0017 0.0074 0.1008
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0008 0.0011 0.0118
Giardia lamblia Cysteine protease 0.0111 0.0724 0.2009
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0079 0.0506 0.0505
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0008 0.0008 0.0014
Echinococcus granulosus voltage gated potassium channel 0.0017 0.007 0.0069
Entamoeba histolytica prolyl oligopeptidase family protein 0.0013 0.0048 0.0198
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0017 0.0074 0.1008
Echinococcus multilocularis importin subunit beta 1 0.0023 0.0117 0.0115
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0056 0.0346 0.0345
Trypanosoma brucei developmentally regulated phosphoprotein 0.0008 0.0011 0.0024
Entamoeba histolytica Ran family GTPase 0.0017 0.0074 0.0331
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0049 0.0292 0.0289
Trichomonas vaginalis glutaminase, putative 0.0108 0.0703 0.1954
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0049 0.0294 0.0291
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.145 1 1
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0011 0.0028 0.0077
Brugia malayi nuclear receptor RXR 0.0054 0.0332 0.0331
Brugia malayi hypothetical protein 0.0167 0.1112 0.1111
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0296 0.2004 0.5578
Trypanosoma cruzi DNA topoisomerase II, putative 0.0008 0.0011 0.0004
Entamoeba histolytica cysteine protease, putative 0.0113 0.0739 0.3664
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0034 0.0194 0.0191
Trichomonas vaginalis DNA polymerase eta, putative 0.0013 0.0048 0.013
Onchocerca volvulus 0.0296 0.2004 1
Brugia malayi Cytochrome P450 family protein 0.0052 0.0315 0.0314
Entamoeba histolytica cysteine proteinase, putative 0.0293 0.1989 0.9923
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0008 0.0011 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0103 0.0668 0.0667
Entamoeba histolytica cysteine protease, putative 0.0113 0.0739 0.3664
Toxoplasma gondii heat shock protein HSP90 0.0052 0.0315 0.0857
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0008 0.0008 0.0004
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0111 0.0724 0.3587
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0034 0.0191 0.092
Trypanosoma cruzi heat shock protein 90, putative 0.0044 0.0259 0.0252
Toxoplasma gondii melibiase subfamily protein 0.003 0.0163 0.0434
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0296 0.2004 0.2003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0315 0.2135 0.5941
Leishmania major developmentally regulated phosphoprotein-like protein 0.0008 0.0011 0.0024
Echinococcus multilocularis geminin 0.0526 0.36 0.3599
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0079 0.0502 0.0495
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0079 0.0502 0.0501
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0103 0.0668 0.0666
Onchocerca volvulus 0.0049 0.0292 0.1423
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0071 0.007
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Toxoplasma gondii cathepsin CPL 0.0296 0.2004 0.5569
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.001
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0008 0.0008 0.002
Entamoeba histolytica cysteine protease, putative 0.0111 0.0724 0.3586
Loa Loa (eye worm) hypothetical protein 0.0111 0.0724 0.0723
Echinococcus granulosus lamin dm0 0.0014 0.0054 0.0053
Plasmodium vivax heat shock protein 90, putative 0.0034 0.0191 0.092
Plasmodium vivax serine-repeat antigen (SERA) 0.0111 0.0724 0.3587
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0111 0.0724 0.3587
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0111 0.0724 0.0723
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0049 0.0292 0.0291
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0017 0.0074 0.1842
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0026 0.0136 0.0128
Trypanosoma brucei heat shock protein, putative 0.0052 0.0315 0.087
Brugia malayi cathepsin Z-like cysteine proteinase 0.0111 0.0724 0.0723
Loa Loa (eye worm) hypothetical protein 0.0043 0.0254 0.0252
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Leishmania major cathepsin L-like protease 0.0315 0.2135 0.5941
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0296 0.2004 0.5578
Schistosoma mansoni cathepsin F (C01 family) 0.0296 0.2004 0.2002
Plasmodium vivax DNA topoisomerase II, putative 0.0008 0.0011 0.0018
Mycobacterium tuberculosis Conserved protein 0.0008 0.0011 0.0283
Brugia malayi Cathepsin L-like precursor 0.0296 0.2004 0.2003
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.002 0.0095 0.0093
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0054 0.0332 0.0329
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0071 0.0189
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0008 0.0008 0.0005
Echinococcus multilocularis cpg binding protein 0.0019 0.0087 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0048 0.0125
Echinococcus multilocularis dnaJ subfamily B 0.0256 0.1727 0.1726
Schistosoma mansoni nAChR subunit 0.0079 0.0502 0.05
Trypanosoma cruzi heat shock protein 85, putative 0.0052 0.0315 0.0307
Toxoplasma gondii leucyl aminopeptidase LAP 0.0063 0.039 0.1067
Leishmania major protein kinase A regulatory subunit, putative 0.0008 0.0008 0.0014
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0013 0.0042 0.0039
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0017 0.0074 0.1008
Schistosoma mansoni cpg binding protein 0.0019 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0356 0.2424 0.2423
Entamoeba histolytica cysteine proteinase, putative 0.0113 0.0739 0.3664
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0011 0.0034 0.0092
Echinococcus multilocularis disco interacting protein 2 0.0007 0.0003 0.0002
Echinococcus granulosus lipoxygenase domain containing protein 0.0035 0.0197 0.0195
Loa Loa (eye worm) hypothetical protein 0.0035 0.0197 0.0196
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0048 0.0289 0.7342
Brugia malayi RNA, U transporter 1 0.0066 0.0413 0.0412
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0111 0.0724 0.2013
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.145 1 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Entamoeba histolytica cysteine proteinase, putative 0.0113 0.0739 0.3664
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0017 0.0074 0.1842
Schistosoma mansoni rab6-interacting 0.0035 0.0197 0.0194
Echinococcus multilocularis leucyl aminopeptidase 0.0013 0.0042 0.0041
Echinococcus granulosus patatin phospholipase domain containing protein 0.0008 0.0008 0.0007
Trichomonas vaginalis endoplasmin, putative 0.0038 0.0218 0.0604
Trypanosoma cruzi heat shock protein 85, putative 0.0052 0.0315 0.0307
Schistosoma mansoni acetylcholine receptor subunit beta 0.0036 0.0208 0.0205
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. 0.0007 0.0003 0.0076
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0014 0.0055 0.0047
Brugia malayi hypothetical protein 0.0054 0.0332 0.0331
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0011 0.0035 0.0866
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0015 0.0059 0.0057
Trichomonas vaginalis receptor histidine kinase, putative 0.0011 0.0028 0.0077
Plasmodium falciparum serine repeat antigen 4 0.0111 0.0724 0.3587
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0103 0.0668 0.0667
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0011 0.0028 0.0077
Brugia malayi cathepsin Z-like cysteine proteinase 0.0111 0.0724 0.0723
Schistosoma mansoni microtubule-associated protein tau 0.029 0.1965 0.1963
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0052 0.0315 0.4457
Trypanosoma brucei cAMP response protein 1, putative 0.0008 0.0008 0.0014
Schistosoma mansoni intermediate filament proteins 0.0014 0.0054 0.0051
Brugia malayi Protein kinase domain containing protein 0.0009 0.002 0.0018
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0008 0.0008 0.0007
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0013 0.0048 0.0125
Echinococcus multilocularis 0.0017 0.0074 0.0072
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.007 0.0067
Echinococcus multilocularis thyroid hormone receptor alpha 0.0239 0.1614 0.1613
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Onchocerca volvulus 0.0019 0.0088 0.0404
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0016 0.0067 0.092
Plasmodium vivax unspecified product 0.0111 0.0724 0.3587
Echinococcus granulosus leucyl aminopeptidase 0.0013 0.0042 0.0041
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0296 0.2004 0.2003
Onchocerca volvulus 0.0035 0.02 0.0965
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0079 0.0506 0.0505
Echinococcus granulosus cGMP dependent protein kinase 1 0.0008 0.0013 0.0012
Toxoplasma gondii histone lysine methyltransferase SET1 0.0036 0.0202 0.0543
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.001 0.0024 0.0293
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0079 0.0502 0.1391
Brugia malayi Immunoglobulin I-set domain containing protein 0.0009 0.0015 0.0013
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0017 0.0074 0.1008
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0284 0.0283
Leishmania major hypothetical protein, conserved 0.0008 0.0008 0.0014
Entamoeba histolytica cysteine proteinase, putative 0.0113 0.0739 0.3664
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0008 0.0011 0.0018
Echinococcus granulosus nAChR subunit 0.0079 0.0502 0.0501
Onchocerca volvulus 0.0014 0.0054 0.0232
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0315 0.2135 0.5941
Brugia malayi acetyltransferase, GNAT family protein 0.0049 0.0294 0.0293
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0008 0.0011 0.001
Trichomonas vaginalis set domain proteins, putative 0.0089 0.057 0.1584
Brugia malayi hypothetical protein 0.0035 0.0197 0.0195
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Echinococcus granulosus leucyl aminopeptidase 0.0013 0.0042 0.0041
Loa Loa (eye worm) hypothetical protein 0.002 0.0094 0.0093
Schistosoma mansoni hypothetical protein 0.0009 0.0015 0.0012
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.001 0.0025 0.0022
Brugia malayi hypothetical protein 0.0035 0.0197 0.0195
Loa Loa (eye worm) hypothetical protein 0.0167 0.1112 0.1111
Brugia malayi cathepsin L-like cysteine proteinase 0.0111 0.0724 0.0723
Echinococcus granulosus mitogen activated protein kinase 0.0079 0.0502 0.0501
Entamoeba histolytica cysteine protease, putative 0.0111 0.0724 0.3586
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0103 0.0668 0.0667
Trypanosoma brucei trypanothione reductase 0.0015 0.0059 0.0157
Toxoplasma gondii HEAT repeat-containing protein 0.0023 0.0117 0.0303
Echinococcus granulosus cGMP dependent protein kinase 0.0008 0.0013 0.0012
Schistosoma mansoni neurotransmitter gated ion channel 0.0036 0.0208 0.0205
Echinococcus granulosus netrin receptor unc 5 0.0009 0.0015 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0103 0.0668 0.0667
Brugia malayi latrophilin 2 splice variant baaae 0.0122 0.0798 0.0797
Entamoeba histolytica cysteine protease, putative 0.0113 0.0739 0.3664
Loa Loa (eye worm) hypothetical protein 0.0043 0.025 0.0249
Schistosoma mansoni carbonic anhydrase-related 0.0028 0.0152 0.0149
Trypanosoma brucei heat shock protein, putative 0.0052 0.0315 0.087
Trichomonas vaginalis receptor histidine kinase, putative 0.0011 0.0028 0.0077
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.002 0.0094 0.026
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0034 0.0031
Loa Loa (eye worm) CXXC zinc finger family protein 0.0018 0.008 0.0079
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0017 0.0074 0.1842
Brugia malayi Cathepsin L-like precursor 0.0296 0.2004 0.2003
Mycobacterium ulcerans two component regulator - sensor kinase 0.001 0.0024 0.0293
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0079 0.0502 0.0501
Trichomonas vaginalis penicillin-binding protein, putative 0.001 0.0025 0.0068
Entamoeba histolytica cysteine protease, putative 0.0296 0.2004 1
Trypanosoma cruzi prolyl endopeptidase 0.0013 0.0048 0.004
Onchocerca volvulus Cathepsin L homolog 0.0111 0.0724 0.3587
Toxoplasma gondii preprocathepsin c precursor, putative 0.0111 0.0724 0.1998
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0387 0.0384
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0024
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0102 0.066 0.0653
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0079 0.0502 0.0501
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0056 0.0346 0.0344
Giardia lamblia Pms1-like protein 0.0008 0.0011 0.0024
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0009 0.0017 0.0009
Loa Loa (eye worm) hypothetical protein 0.0103 0.0668 0.0667
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Brugia malayi small heat shock protein 0.0343 0.2335 0.2334
Echinococcus granulosus Dipeptidyl peptidase 9 0.0056 0.0346 0.0344
Brugia malayi Uncoordinated protein 44 0.0009 0.0015 0.0013
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0009 0.002 0.0055
Mycobacterium ulcerans hypothetical protein 0.0054 0.0327 0.4628
Echinococcus multilocularis nmda type glutamate receptor 0.0048 0.0291 0.029
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0008 0.0011 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0724 0.2013
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0015 0.0059 0.1477
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0036 0.0208 0.0207
Entamoeba histolytica cysteine protease, putative 0.0113 0.0739 0.3664
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0017 0.0074 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0739 0.2056
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0111 0.0724 0.2013
Schistosoma mansoni heat shock protein 0.0034 0.0191 0.0188
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0178 0.1188 0.1187
Echinococcus multilocularis leucine aminopeptidase protein 0.0063 0.039 0.0389
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0007 0.0003 0.0076
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0103 0.0668 0.0667
Loa Loa (eye worm) hypothetical protein 0.145 1 1
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0332 0.0331
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0056 0.0346 0.0345
Echinococcus multilocularis carbonic anhydrase II 0.0076 0.0483 0.0482
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0122 0.0801 0.08
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0013 0.0048 0.0125
Plasmodium falciparum carbonic anhydrase 0.0028 0.0152 0.072
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0063 0.039 1
Loa Loa (eye worm) beta-lactamase 0.001 0.0025 0.0024
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0079 0.0502 0.0501
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0013 0.0048 0.0198
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Toxoplasma gondii cathepsin B 0.0525 0.3593 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0014 0.0055 0.0047
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0036 0.0208 0.0207
Loa Loa (eye worm) hypothetical protein 0.0111 0.0724 0.0723
Echinococcus granulosus nAChR subunit 0.0043 0.025 0.0249
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0008 0.0012 0.0004
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.001 0.0025 0.0024
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0009 0.002 0.0055
Entamoeba histolytica cysteine protease, putative 0.0113 0.0739 0.3664
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0136 0.0901 0.09
Echinococcus granulosus cGMP dependent protein kinase 1 0.0008 0.0013 0.0012
Trypanosoma brucei protein kinase, putative 0.0079 0.0502 0.1391
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Schistosoma mansoni loxhd1 0.0035 0.0197 0.0194
Mycobacterium ulcerans hypothetical protein 0.0008 0.0008 0.0067
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0008 0.0011 0.001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0013 0.0048 0.004
Loa Loa (eye worm) nuclear receptor NHR-67 0.0049 0.0292 0.0291
Brugia malayi beta-lactamase 0.001 0.0025 0.0024
Leishmania major carbonic anhydrase-like protein 0.0076 0.0483 0.1339
Loa Loa (eye worm) carbonic anhydrase 3 0.0076 0.0483 0.0482
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0724 0.2013
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0038 0.0218 0.5578
Echinococcus granulosus disco interacting protein 2 0.0007 0.0003 0.0002
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0079 0.0502 0.0495
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0079 0.0502 0.0501
Giardia lamblia Cathepsin B precursor 0.0111 0.0724 0.2009
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0111 0.0724 0.2013
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0008 0.0008 0.0007
Onchocerca volvulus 0.001 0.0025 0.0087
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0094 0.061 0.3016
Brugia malayi MH2 domain containing protein 0.0037 0.0214 0.0213
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0103 0.0668 0.0667
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0079 0.0502 0.1391
Giardia lamblia Alanyl dipeptidyl peptidase 0.0013 0.0048 0.0125
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Loa Loa (eye worm) hypothetical protein 0.0104 0.0678 0.0677
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0296 0.2004 0.5578
Echinococcus multilocularis mitogen activated protein kinase 0.0079 0.0502 0.0501
Echinococcus multilocularis Ankyrin 0.0009 0.0015 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0017 0.0074 0.1842
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.0292 0.0291
Loa Loa (eye worm) hypothetical protein 0.0012 0.0035 0.0034
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0053 0.0324 0.0901
Onchocerca volvulus 0.0296 0.2004 1
Plasmodium falciparum heat shock protein 90, putative 0.0194 0.1301 0.6477
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0008 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0079 0.0502 0.0495
Echinococcus granulosus glycine receptor subunit alpha 1 0.0122 0.0801 0.08
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Trypanosoma cruzi cysteine peptidase, putative 0.0315 0.2135 0.2129
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0079 0.0502 0.0501
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0079 0.0502 0.0501
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0111 0.0724 0.2013
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0013 0.0048 0.0198
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0167 0.1115 0.1113
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0002
Plasmodium falciparum heat shock protein 90, putative 0.003 0.0162 0.0772
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0024
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0073 0.0459 0.0457
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0008 0.0011 0.0018
Loa Loa (eye worm) endoplasmin 0.0052 0.0315 0.0314
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0063 0.039 0.108
Loa Loa (eye worm) hypothetical protein 0.0008 0.0008 0.0006
Trypanosoma brucei prolyl endopeptidase 0.0013 0.0048 0.0125
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0079 0.0502 0.0501
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0008 0.0013 0.0012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0079 0.0502 0.0501
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0011 0.0033 0.0821
Trypanosoma cruzi heat shock protein 90, putative 0.0022 0.0109 0.0101
Loa Loa (eye worm) hypothetical protein 0.0122 0.0798 0.0797
Mycobacterium ulcerans esterase/lipase LipP 0.001 0.0025 0.0315
Echinococcus granulosus dnaJ subfamily B 0.0256 0.1727 0.1726
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0056 0.0346 0.0338
Entamoeba histolytica cysteine protease, putative 0.0113 0.0739 0.3664
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0021 0.0103 0.2642
Plasmodium falciparum heat shock protein 90 0.0052 0.0315 0.1539
Schistosoma mansoni hypothetical protein 0.0056 0.0346 0.0343
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0028 0.0152 0.015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0094 0.061 0.1696
Brugia malayi hypothetical protein 0.0036 0.0208 0.0207
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.001 0.0024 0.059
Trichomonas vaginalis heat shock protein, putative 0.0048 0.0289 0.0802
Mycobacterium ulcerans heat shock protein 90 0.0048 0.0289 0.4084
Echinococcus granulosus carbonic anhydrase 0.0028 0.0152 0.015
Trypanosoma brucei cAMP binding protein, putative 0.0008 0.0008 0.0014
Schistosoma mansoni RAR-like nuclear receptor 0.0103 0.0668 0.0666
Loa Loa (eye worm) cysteine protease 0.0296 0.2004 0.2003
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0017 0.0074 0.0066
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0111 0.0724 0.2009
Leishmania major phosphopantetheinyl transferase-like protein 0.0008 0.0008 0.0014
Echinococcus granulosus acylamino acid releasing enzyme 0.0013 0.0048 0.0046
Echinococcus multilocularis carbonic anhydrase 0.0028 0.0152 0.015
Loa Loa (eye worm) hypothetical protein 0.0017 0.007 0.0069
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0017 0.0074 0.0185
Loa Loa (eye worm) acetyltransferase 0.0049 0.0294 0.0293
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0008 0.0008 0.0194
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0008 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.001
Echinococcus granulosus nmda type glutamate receptor 0.0048 0.0291 0.029
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0044 0.0259 0.0258
Loa Loa (eye worm) hypothetical protein 0.0103 0.0668 0.0667
Echinococcus granulosus jun protein 0.005 0.0302 0.03
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.145 1 1
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0008 0.0008 0.0006
Echinococcus granulosus nuclear factor of activated T cells 5 0.0044 0.0259 0.0258
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0046 0.0275 0.6894
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0024
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0017 0.0074 0.0332
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0008 0.0012 0.0295
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0111 0.0724 0.2013
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.0292 0.0291
Schistosoma mansoni aldehyde dehydrogenase 0.0047 0.0278 0.0275
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.001 0.0024 0.0293
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0008 0.0005
Echinococcus multilocularis cysteine protease 0.0296 0.2004 0.2003
Trypanosoma brucei carbonic anhydrase-like protein 0.0076 0.0483 0.1339
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0315 0.2135 0.5941
Brugia malayi Cathepsin L-like precursor 0.0293 0.1989 0.1988
Leishmania major hypothetical protein, conserved 0.0008 0.0008 0.0014
Plasmodium falciparum serine repeat antigen 3 0.0111 0.0724 0.3587
Mycobacterium ulcerans lipase LipD 0.001 0.0025 0.0315
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Treponema pallidum fructose-bisphosphate aldolase 0.0094 0.061 1
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0008 0.0008 0.0005
Plasmodium falciparum glutathione reductase 0.0015 0.0059 0.0257
Schistosoma mansoni aldehyde dehydrogenase 0.0047 0.0278 0.0275
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0014 0.0055 0.0132
Loa Loa (eye worm) hypothetical protein 0.0043 0.025 0.0249
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0724 0.2013
Loa Loa (eye worm) glutaminase 0.0108 0.0703 0.0701
Echinococcus multilocularis lipoxygenase domain containing protein 0.0035 0.0197 0.0195
Loa Loa (eye worm) hypothetical protein 0.0103 0.0668 0.0667
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0014 0.0054 0.0053
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0071 0.0068
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0008 0.0012 0.0025
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0111 0.0724 0.3587
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0122 0.0801 0.08
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0103 0.0668 0.0667
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0034 0.0194 0.0193
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0103 0.0668 0.0667
Brugia malayi nuclear receptor NHR-88 0.0103 0.0668 0.0667
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0079 0.0502 0.0501
Mycobacterium tuberculosis Polyketide synthase Pks13 0.003 0.0163 0.4088
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Onchocerca volvulus 0.0043 0.025 0.1214
Trypanosoma brucei aminopeptidase, putative 0.0013 0.0042 0.011
Brugia malayi prolyl oligopeptidase family protein 0.0167 0.1115 0.1114
Echinococcus multilocularis thioredoxin glutathione reductase 0.0015 0.006 0.0059
Trichomonas vaginalis guanylate cyclase, putative 0.0009 0.002 0.0055
Echinococcus multilocularis tumor protein p63 0.0239 0.1611 0.161
Onchocerca volvulus 0.0089 0.057 0.2817
Echinococcus granulosus cathepsin l1 0.0293 0.1989 0.1988
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0013 0.0042 0.011
Onchocerca volvulus 0.0293 0.1989 0.9923
Mycobacterium leprae Probable polyketide synthase Pks1 0.0021 0.0103 0.2642
Brugia malayi nuclear receptor NHR-67 0.0049 0.0292 0.0291
Onchocerca volvulus Prolyl endopeptidase homolog 0.0013 0.0048 0.0199
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0085 0.0542 0.0541
Echinococcus granulosus heat shock protein 90 0.0044 0.0259 0.0258
Mycobacterium ulcerans thioesterase 0.0017 0.0071 0.0977
Schistosoma mansoni cytochrome P450 0.0017 0.0074 0.0071
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0014 0.0055 0.0145
Echinococcus granulosus heat shock protein 90 0.0052 0.0315 0.0314
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0054 0.0332 0.0331
Schistosoma mansoni rab6-interacting 0.0035 0.0197 0.0194
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.001 0.0024 0.0603
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0008 0.0011 0.0018
Entamoeba histolytica heat shock protein 90, putative 0.0052 0.0315 0.1538
Trichomonas vaginalis ran, putative 0.0017 0.0074 0.0204
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.0292 0.0291
Brugia malayi hypothetical protein 0.0036 0.0208 0.0207
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0034 0.0191 0.0919
Brugia malayi hypothetical protein 0.0039 0.0227 0.0226
Mycobacterium leprae Possible regulatory protein 0.0008 0.0012 0.0297
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0013 0.0048 0.004
Trypanosoma brucei importin beta-1 subunit, putative 0.0023 0.0117 0.0317
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0034 0.0194 0.2729
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0087 0.0079
Brugia malayi Egg laying defective protein 4 0.0008 0.0013 0.0011
Brugia malayi hypothetical protein 0.0093 0.0602 0.0601
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0103 0.0668 0.0667
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0025 0.0062
Giardia lamblia Cathepsin B precursor 0.0111 0.0724 0.2009
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0111 0.0724 0.3587
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0008 0.0012 0.001
Brugia malayi cathepsin L precursor 0.0111 0.0724 0.0723
Plasmodium falciparum peptidase, putative 0.0013 0.0048 0.0199
Onchocerca volvulus 0.001 0.0025 0.0087
Plasmodium falciparum LCCL domain-containing protein 0.0035 0.0197 0.0946
Trypanosoma brucei heat shock protein 90, putative 0.0052 0.0315 0.087
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0026 0.0136 0.0371
Brugia malayi hypoxia-induced factor 1 0.0096 0.0622 0.0621
Schistosoma mansoni nAChR subunit 0.0079 0.0502 0.05
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0079 0.0502 0.05
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0008 0.0008 0.0194
Loa Loa (eye worm) TOPoisomerase family member 0.0008 0.0011 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0025 0.0062
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0007 0.0003 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0012 0.0035 0.0032
Echinococcus granulosus thioredoxin glutathione reductase 0.0015 0.006 0.0059
Brugia malayi hypothetical protein 0.0036 0.0208 0.0207
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0048 0.0289 0.0798
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0017 0.0074 0.1842
Toxoplasma gondii Hsp90 domain-containing protein 0.0194 0.1301 0.3607
Schistosoma mansoni acetylcholine receptor-related 0.0036 0.0208 0.0205
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0017 0.0074 0.1008
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0007 0.0003 0.0076
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0063 0.039 0.9777
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0011 0.003 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0025 0.0017
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Leishmania major heat shock protein, putative 0.0034 0.0191 0.0525
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0087 0.024
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0009 0.0015 0.0014
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0079 0.0502 0.0501
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0111 0.0724 0.2013
Echinococcus multilocularis Glycoside hydrolase, family 27 0.003 0.0163 0.0162
Brugia malayi Intermediate filament tail domain containing protein 0.0014 0.0054 0.0053
Brugia malayi Disco-interacting protein 2 homolog 0.0007 0.0003 0.0002
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0017 0.0074 0.0197
Mycobacterium ulcerans DNA polymerase IV 0.0013 0.0048 0.0636
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0111 0.0724 0.0721
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0122 0.0801 0.0798
Loa Loa (eye worm) heat shock protein 90 0.0052 0.0315 0.0314
Onchocerca volvulus 0.0019 0.0087 0.0399
Mycobacterium tuberculosis Probable lipase LipD 0.001 0.0025 0.0627
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0017 0.0076 0.0069
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0103 0.0668 0.0666
Plasmodium falciparum cysteine proteinase falcipain 1 0.0113 0.0739 0.3664
Leishmania major cytochrome p450-like protein 0.0017 0.0074 0.0197
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0026 0.0136 0.0133
Trypanosoma brucei heat shock protein 84, putative 0.0034 0.0191 0.0525
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0027 0.0142 0.014
Entamoeba histolytica hypothetical protein 0.0019 0.0086 0.0391
Echinococcus granulosus thyroid hormone receptor alpha 0.0049 0.0292 0.0291
Entamoeba histolytica cysteine proteinase 2 0.0113 0.0739 0.3664
Loa Loa (eye worm) glutaminase 2 0.0108 0.0703 0.0701
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0034 0.0194 0.2729
Mycobacterium ulcerans aldehyde dehydrogenase 0.0047 0.0278 0.3934
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0014 0.0055 0.0151
Entamoeba histolytica cysteine protease, putative 0.0113 0.0739 0.3664
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Plasmodium falciparum serine repeat antigen 1 0.0111 0.0724 0.3587
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0017 0.0074 0.1008
Entamoeba histolytica prolyl oligopeptidase family protein 0.0013 0.0048 0.0198
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0053 0.0324 0.0901
Trypanosoma brucei PAB1-binding protein , putative 0.0022 0.0109 0.0296
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0028 0.0152 0.015
Trichomonas vaginalis CMGC family protein kinase 0.0079 0.0502 0.1396
Onchocerca volvulus 0.0035 0.0197 0.0946
Giardia lamblia Hypothetical protein 0.0111 0.0724 0.2009
Schistosoma mansoni jun-related protein 0.0041 0.0237 0.0234
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0122 0.0801 0.0798
Loa Loa (eye worm) hypothetical protein 0.0343 0.2335 0.2334
Toxoplasma gondii heat shock protein 75, putative 0.0034 0.0191 0.0512
Toxoplasma gondii LsmAD domain-containing protein 0.0022 0.0109 0.0283
Schistosoma mansoni carbonic anhydrase-related 0.0028 0.0152 0.0149
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0086 0.0548 0.0547
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Trypanosoma cruzi cysteine proteinase, putative 0.0113 0.0739 0.0732
Brugia malayi hypothetical protein 0.0022 0.0109 0.0108
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0034 0.0194 0.0193
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0296 0.2004 1
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0063 0.039 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0046
Onchocerca volvulus 0.0012 0.0035 0.0138
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0034 0.0194 0.0533
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0315 0.0314
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0008 0.0011 0.001
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0028 0.0152 0.015
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0026 0.0136 0.0135
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0087 0.206
Onchocerca volvulus 0.0023 0.0115 0.0537
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0111 0.0724 0.3587
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0113 0.0739 0.0737
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0387 0.0384
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0027 0.0142 0.0139
Schistosoma mansoni ankyrin 23/unc44 0.0009 0.0015 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0017 0.0074 0.1842
Schistosoma mansoni cellular tumor antigen P53 0.0035 0.0198 0.0195
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0036 0.0208 0.0207
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0103 0.0668 0.0667
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0008 0.0013 0.0012
Trichomonas vaginalis adenylate cyclase, putative 0.0009 0.002 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0017 0.0074 0.1842
Trypanosoma cruzi cysteine protease, putative 0.0113 0.0739 0.0732
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0011 0.0034 0.0033
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0111 0.0724 0.2009
Loa Loa (eye worm) hypothetical protein 0.0014 0.0054 0.0053
Onchocerca volvulus 0.0014 0.0054 0.0232
Leishmania major cysteine peptidase A (CPA) 0.0296 0.2004 0.5575
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0024
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0103 0.0668 0.0666
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0013 0.0048 0.1217
Echinococcus multilocularis nAChR subunit 0.0043 0.025 0.0249
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0076 0.0483 0.0482
Entamoeba histolytica cysteine proteinase, putative 0.0296 0.2004 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0008 0.0008 0.0194
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0009 0.0017 0.0009
Echinococcus multilocularis lamin 0.0014 0.0054 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0017 0.0074 0.1842
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0011 0.0033 0.0416
Loa Loa (eye worm) transcription factor SMAD2 0.0037 0.0214 0.0213
Echinococcus granulosus endoplasmin 0.0048 0.0289 0.0288
Schistosoma mansoni hypothetical protein 0.0122 0.0798 0.0796
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0013 0.0042 0.0041
Trypanosoma brucei importin beta-1 subunit, putative 0.0023 0.0117 0.0317
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0013 0.0042 0.0041
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Loa Loa (eye worm) MH2 domain-containing protein 0.0037 0.0214 0.0213
Giardia lamblia Grp94/Hsp90 0.0048 0.0289 0.0797
Echinococcus granulosus glutamate receptor NMDA 0.0046 0.0275 0.0274
Entamoeba histolytica hypothetical protein 0.0043 0.025 0.1213
Mycobacterium tuberculosis Probable esterase LipL 0.001 0.0025 0.0627
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0048 0.004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0103 0.0668 0.0667
Brugia malayi excitatory GABA receptor EXP-1A 0.0079 0.0502 0.0501
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.002 0.0095 0.2367
Echinococcus granulosus histone acetyltransferase KAT2B 0.0014 0.0055 0.0054
Loa Loa (eye worm) AGC/PKG protein kinase 0.0008 0.0013 0.0011
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0008 0.0008 0.0194
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0103 0.0668 0.0667
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0007 0.0003 0.0078
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0048 0.004
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0007 0.0003 0.007
Schistosoma mansoni hypothetical protein 0.0248 0.1673 0.1671
Toxoplasma gondii thioredoxin reductase 0.0015 0.0059 0.0143
Toxoplasma gondii ABC1 family protein 0.001 0.0025 0.0048
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0008 0.0008 0.0007
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0079 0.0502 0.1379
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0011 0.0034 0.0033
Plasmodium falciparum ataxin-2 like protein, putative 0.0022 0.0109 0.0507
Brugia malayi hypothetical protein 0.0014 0.0055 0.0053
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0113 0.0739 0.0737
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0048 0.0125
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0013 0.0042 0.011
Schistosoma mansoni nAChR subunit 0.0036 0.0208 0.0205
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0013 0.0042 0.011
Brugia malayi Cathepsin L-like precursor 0.0296 0.2004 0.2003
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0079 0.0502 0.05
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0017 0.0074 0.1008
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0008 0.0011 0.0004
Plasmodium vivax heat shock protein, putative 0.0194 0.1301 0.6477
Schistosoma mansoni ran 0.0017 0.0074 0.0071
Trichomonas vaginalis heat shock protein, putative 0.0038 0.0218 0.0604
Onchocerca volvulus Fatty acid synthase homolog 0.0036 0.0206 0.0993
Plasmodium vivax vivapain-3 0.0113 0.0739 0.3664
Trypanosoma cruzi cruzipain precursor, putative 0.0315 0.2135 0.2129
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0071 0.0176
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0167 0.1115 0.5548
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Trypanosoma cruzi cysteine peptidase, putative 0.0296 0.2004 0.1998
Loa Loa (eye worm) intermediate filament protein 0.0014 0.0054 0.0053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0296 0.2004 0.5578
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0021 0.0103 0.2583
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0013 0.0048 0.013
Loa Loa (eye worm) hypothetical protein 0.0103 0.0668 0.0667
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0007 0.0003 0.0078
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0079 0.0502 0.0501
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0071 0.0069
Onchocerca volvulus Protein ultraspiracle homolog 0.0103 0.0668 0.3309
Echinococcus multilocularis cathepsin b 0.145 1 1
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0008 0.0008 0.0006
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0111 0.0724 0.0721
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0031 0.0173 0.0172
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0013 0.0048 0.0125
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0008 0.0011 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0315 0.2135 0.5941
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0296 0.2004 0.5578
Brugia malayi hypothetical protein 0.0054 0.0332 0.0331
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0008 0.0007
Toxoplasma gondii type I fatty acid synthase, putative 0.0022 0.0106 0.0275
Schistosoma mansoni DNA topoisomerase II 0.0008 0.0011 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0017 0.0074 0.1842
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0008 0.0008 0.0005
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0007 0.0003 0.0002
Schistosoma mansoni nuclear receptor nhr-48 0.0049 0.0292 0.0289
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0079 0.0502 0.0501
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0019 0.0087 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0012 0.003
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0008 0.0008 0.0001
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0071 0.0063
Schistosoma mansoni nuclear receptor 0.0049 0.0292 0.0289
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0013 0.0048 0.0045
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0071 0.0176
Echinococcus multilocularis nmda type glutamate receptor 0.0062 0.0383 0.0382
Toxoplasma gondii prolyl endopeptidase 0.0013 0.0048 0.0111
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.001 0.0024 0.059
Schistosoma mansoni nAChR subunit 0.0079 0.0502 0.05
Onchocerca volvulus Netrin receptor homolog 0.0009 0.0015 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0293 0.1989 0.5535
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0008 0.0011 0.001
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0113 0.0739 0.2052
Entamoeba histolytica cysteine protease, putative 0.0111 0.0724 0.3586
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0071 0.007
Giardia lamblia Cathepsin L precursor 0.0111 0.0724 0.2009
Loa Loa (eye worm) latrophilin receptor protein 2 0.0056 0.0346 0.0344
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0087 0.1196
Plasmodium vivax vivapain-2 0.0296 0.2004 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0054 0.0327 0.8186
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0079 0.0502 0.0501
Brugia malayi prolyl oligopeptidase family protein 0.0013 0.0048 0.0046
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0028 0.0152 0.015
Loa Loa (eye worm) prolyl oligopeptidase 0.0167 0.1115 0.1114
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0017 0.0074 0.1008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Echinococcus granulosus glycine receptor subunit alpha 1 0.0122 0.0801 0.08
Loa Loa (eye worm) hypothetical protein 0.0103 0.0668 0.0667
Brugia malayi cytoplasmic intermediate filament protein 0.0008 0.0008 0.0007
Plasmodium vivax vivapain-1 0.0113 0.0739 0.3664
Echinococcus multilocularis lipoxygenase domain containing protein 0.0035 0.0197 0.0195
Brugia malayi prolyl oligopeptidase family protein 0.0013 0.0048 0.0046
Giardia lamblia Cysteine protease 0.0111 0.0724 0.2009
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0054 0.0332 0.0331
Schistosoma mansoni hypothetical protein 0.0017 0.0074 0.0071
Echinococcus granulosus L aminoadipate semialdehyde 0.0027 0.0142 0.0141
Giardia lamblia Fructose-bisphosphate aldolase 0.0094 0.061 0.1691
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0094 0.061 0.1696
Schistosoma mansoni carbonic anhydrase-related 0.0028 0.0152 0.0149
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0296 0.2004 0.2003
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0025 0.0017
Schistosoma mansoni polycystin 1-related 0.0035 0.0197 0.0194
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.003 0.0163 0.0162
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0724 0.2013
Mycobacterium tuberculosis Conserved protein 0.001 0.0025 0.0627
Echinococcus multilocularis nAChR subunit 0.0079 0.0502 0.0501
Onchocerca volvulus 0.0079 0.0502 0.2478
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.001 0.0024 0.0023
Loa Loa (eye worm) fatty acid synthase 0.002 0.0093 0.0091
Chlamydia trachomatis cytosol aminopeptidase 0.0063 0.039 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0034 0.0191 0.4794
Trypanosoma cruzi major cysteine proteinase, putative 0.013 0.0855 0.0848
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0009 0.0015 0.0012
Schistosoma mansoni hypothetical protein 0.0056 0.0346 0.0343
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0034 0.0191 0.4794
Giardia lamblia Cathepsin B precursor 0.0525 0.3593 1
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0079 0.0502 0.0501
Trypanosoma brucei DNA topoisomerase ii 0.0008 0.0011 0.0024
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0011 0.0033 0.0655
Plasmodium falciparum serine repeat antigen 2 0.0111 0.0724 0.3587
Trypanosoma brucei prolyl oligopeptidase, putative 0.0013 0.0048 0.0125
Entamoeba histolytica cysteine proteinase 1, putative 0.0113 0.0739 0.3664
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0079 0.0502 0.0501
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0014 0.0055 0.0132
Leishmania major cathepsin L-like protease 0.0296 0.2004 0.5575
Echinococcus granulosus aryl hydrocarbon receptor 0.0008 0.0012 0.001
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0079 0.0502 0.0501
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0013 0.0047 0.1216
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0021 0.0103 0.2583
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0017 0.0074 0.1008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0152 0.015
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0111 0.0724 0.0721
Loa Loa (eye worm) hypothetical protein 0.0293 0.1989 0.1988
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0008 0.0011 0.001
Echinococcus multilocularis Polycystic kidney disease protein 0.0035 0.0197 0.0195
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0071 0.0189
Loa Loa (eye worm) hypothetical protein 0.0086 0.0548 0.0547
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0056 0.0346 0.0338
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0079 0.0502 0.0495
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0007 0.0003 0.0076
Trypanosoma cruzi DNA polymerase kappa, putative 0.0013 0.0048 0.004
Plasmodium falciparum serine repeat antigen 9 0.0111 0.0724 0.3587
Plasmodium falciparum cysteine proteinase falcipain 3 0.0296 0.2004 1
Loa Loa (eye worm) prolyl oligopeptidase 0.0013 0.0048 0.0046
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0056 0.0346 0.0345
Echinococcus multilocularis glutamate receptor NMDA 0.0046 0.0275 0.0274
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0012 0.0035 0.0032
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0034 0.0033
Brugia malayi nuclear receptor NHR-88 0.0049 0.0292 0.0291
Echinococcus granulosus histone lysine methyltransferase setb 0.0012 0.0035 0.0034
Schistosoma mansoni lipoxygenase 0.006 0.0368 0.0365
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0056 0.0346 0.0955
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0047 0.0278 0.0277
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0103 0.0668 0.0667
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0094 0.061 0.1696
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0017 0.0074 0.1008
Echinococcus multilocularis nuclear receptor nhr 48 0.0049 0.0292 0.0291
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0013 0.0042 0.0035
Plasmodium vivax vivapain-2 0.0296 0.2004 1
Echinococcus multilocularis heat shock protein 0.0052 0.0315 0.0314
Mycobacterium tuberculosis Probable oxidoreductase 0.0038 0.0218 0.5453
Loa Loa (eye worm) hypothetical protein 0.0336 0.2285 0.2284
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.0292 0.1423
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0296 0.2004 0.5578
Loa Loa (eye worm) hypothetical protein 0.0022 0.0109 0.0108
Giardia lamblia Alanyl dipeptidyl peptidase 0.0013 0.0048 0.0125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0113 0.0739 0.2052
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0034 0.0032
Loa Loa (eye worm) hypothetical protein 0.0014 0.0052 0.0051
Schistosoma mansoni carbonic anhydrase 0.0028 0.0152 0.0149
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0103 0.0668 0.0667
Echinococcus multilocularis netrin receptor unc 5 0.0009 0.0015 0.0014
Mycobacterium ulcerans DNA gyrase subunit B 0.0008 0.0011 0.0118
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0012 0.0035 0.0032
Loa Loa (eye worm) hypothetical protein 0.0036 0.0208 0.0206
Loa Loa (eye worm) hypothetical protein 0.0373 0.2537 0.2536
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0008 0.002
Trypanosoma brucei heat shock protein, putative 0.0052 0.0315 0.087
Brugia malayi Probable DNA topoisomerase II 0.0008 0.0011 0.001
Trypanosoma cruzi DNA topoisomerase II, putative 0.0008 0.0011 0.0004
Schistosoma mansoni hypothetical protein 0.0085 0.0542 0.054
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0007 0.0003 0.0078
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0028 0.0152 0.015
Mycobacterium ulcerans DNA polymerase IV 0.0013 0.0048 0.0636
Schistosoma mansoni aryl hydrocarbon receptor 0.0031 0.0171 0.0168
Mycobacterium leprae Probable lipase LipE 0.001 0.0025 0.0642
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0046 0.0275 0.3891
Schistosoma mansoni hypothetical protein 0.0035 0.0197 0.0194
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0017 0.007 0.0069
Brugia malayi Calcitonin receptor-like protein seb-1 0.0178 0.1188 0.1187
Trypanosoma brucei unspecified product 0.0011 0.0033 0.0084
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.025 0.0249
Leishmania major hypothetical protein, conserved 0.001 0.0025 0.0062
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0017 0.0074 0.1842
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0079 0.0502 0.0501
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0034 0.0031
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0011 0.0033 0.0425
Loa Loa (eye worm) hypothetical protein 0.0093 0.0602 0.0601
Echinococcus granulosus transcription factor Dp 1 0.0015 0.006 0.0059
Echinococcus granulosus intermediate filament protein 0.0014 0.0054 0.0053
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0013 0.0042 0.011
Entamoeba histolytica hypothetical protein 0.0085 0.0542 0.2677
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0315 0.2135 0.5941
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0079 0.0502 0.0501
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0111 0.0724 0.3587
Entamoeba histolytica prolyl oligopeptidase family protein 0.0013 0.0048 0.0198
Loa Loa (eye worm) hypothetical protein 0.0079 0.0502 0.0501
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0178 0.1188 0.1187
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.001 0.0024 0.059
Brugia malayi cathepsin F-like cysteine proteinase 0.0111 0.0724 0.0723
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0102 0.066 0.1832
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0007 0.0003 0.0084
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0094 0.061 0.3016
Loa Loa (eye worm) cathepsin B 0.0525 0.3593 0.3592
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0008 0.0011 0.0004
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0014 0.0055 0.0237
Mycobacterium leprae Conserved hypothetical protein 0.0008 0.0008 0.0198
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0034 0.0191 0.4794
Echinococcus granulosus cathepsin L 0.0113 0.0739 0.0738
Onchocerca volvulus Cathepsin L homolog 0.0296 0.2004 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0525 0.3593 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0292 0.0291
Giardia lamblia Cathepsin B precursor 0.0111 0.0724 0.2009
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0087 0.0395
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0013 0.0048 0.013
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0087 0.0085
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.025 0.0249
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0111 0.0724 0.2009
Brugia malayi Papain family cysteine protease containing protein 0.0111 0.0724 0.0723
Loa Loa (eye worm) hypothetical protein 0.0293 0.1989 0.1988
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0071 0.007
Brugia malayi Cytochrome P450 family protein 0.0028 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0043 0.025 0.0249
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.002 0.0094 0.0091
Trypanosoma brucei Flagellar Member 6 0.0008 0.0008 0.0014
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0013 0.0048 0.119
Leishmania major heat shock protein 83-1 0.0052 0.0315 0.087
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0103 0.0668 0.0666
Entamoeba histolytica cysteine protease, putative 0.0111 0.0724 0.3586
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0103 0.0668 0.0667
Mycobacterium leprae Probable two component sensor kinase MprB 0.001 0.0024 0.0603
Trypanosoma brucei heat shock protein, putative 0.0052 0.0315 0.087
Brugia malayi photoreceptor-specific nuclear receptor 0.0103 0.0668 0.0667
Echinococcus granulosus ecdysone induced protein 78C 0.0103 0.0668 0.0667
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0036 0.0208 0.0207
Brugia malayi Papain family cysteine protease containing protein 0.0113 0.0739 0.0738
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0103 0.0668 0.0667
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0079 0.0502 0.0501
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.005 0.0302 0.03
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0013 0.0048 0.0125
Loa Loa (eye worm) hypothetical protein 0.0043 0.025 0.0249
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0296 0.2004 0.5578
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0017 0.0074 0.1842
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0087 0.0234
Leishmania major cytochrome p450-like protein 0.0017 0.0074 0.0197
Giardia lamblia Heat shock protein HSP 90-alpha 0.0052 0.0315 0.087
Trypanosoma brucei Heat shock protein 83, putative 0.0052 0.0315 0.087
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0064 0.0399 1
Brugia malayi Nuclear hormone receptor-like 1 0.0103 0.0668 0.0667
Schistosoma mansoni leucine aminopeptidase 0.0013 0.0042 0.0039
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0049 0.0292 0.0291
Plasmodium vivax multidomain scavenger receptor, putative 0.0035 0.0197 0.0946
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0034 0.0194 0.0193
Leishmania major importin beta-1 subunit, putative 0.0019 0.0086 0.0232
Loa Loa (eye worm) hypothetical protein 0.0009 0.0015 0.0013
Leishmania major protein kinase, putative 0.0008 0.0013 0.0028
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0034 0.0191 0.4904
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0013 0.0042 0.0041
Brugia malayi glutathione reductase 0.0015 0.0059 0.0058
Echinococcus multilocularis L aminoadipate semialdehyde 0.0027 0.0142 0.0141
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0292 0.0291
Onchocerca volvulus 0.0296 0.2004 1
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0009 0.0017 0.0009
Brugia malayi tailless protein 0.0049 0.0292 0.0291
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0017 0.0074 0.0198
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Schistosoma mansoni nuclear receptor 0.0049 0.0292 0.0289
Echinococcus granulosus geminin 0.0526 0.36 0.3599
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0087 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0048 0.0125
Echinococcus multilocularis leucyl aminopeptidase 0.0013 0.0042 0.0041
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0122 0.0801 0.0798
Echinococcus granulosus importin subunit beta 1 0.0023 0.0117 0.0115
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0021 0.0103 0.2583
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0103 0.0668 0.0667
Loa Loa (eye worm) hypothetical protein 0.0011 0.0034 0.0032
Schistosoma mansoni single-minded 0.0031 0.0171 0.0168
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.001 0.0025 0.0022
Echinococcus multilocularis glycine receptor subunit beta 0.0122 0.0801 0.08
Mycobacterium ulcerans polyketide synthase Pks9 0.0013 0.0047 0.0635
Leishmania major cathepsin L-like protease 0.0315 0.2135 0.5941
Loa Loa (eye worm) hypothetical protein 0.0293 0.1989 0.1988
Giardia lamblia Cathepsin L-like protease 0.0111 0.0724 0.2009
Loa Loa (eye worm) hypothetical protein 0.0296 0.2004 0.2003
Brugia malayi steroid hormone receptor 0.0103 0.0668 0.0667
Echinococcus multilocularis glycine receptor subunit beta 0.0122 0.0801 0.08
Loa Loa (eye worm) steroid hormone receptor 0.0103 0.0668 0.0667
Loa Loa (eye worm) hypothetical protein 0.0008 0.0008 0.0006
Schistosoma mansoni cathepsin F (C01 family) 0.0296 0.2004 0.2002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0103 0.0668 0.0667
Echinococcus granulosus carbonic anhydrase 0.0028 0.0152 0.015
Brugia malayi Cyclic-nucleotide gated cation channel 0.0011 0.0034 0.0032
Trypanosoma cruzi heat shock protein 85, putative 0.0044 0.0259 0.0252
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0079 0.0502 0.0501
Echinococcus granulosus RUN 0.0035 0.0197 0.0195
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0071 0.007
Mycobacterium tuberculosis Probable lipase LipE 0.001 0.0025 0.0627
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0122 0.0801 0.08
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0026 0.0136 0.0135
Trichomonas vaginalis CMGC family protein kinase 0.0079 0.0502 0.1396
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0013 0.0048 0.0045
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0034 0.0191 0.019
Echinococcus multilocularis expressed conserved protein 0.0008 0.0013 0.0012
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.001 0.0024 0.0607
Schistosoma mansoni 60S ribosomal protein L21 0.0009 0.0018 0.0015
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0079 0.0502 0.0501
Trypanosoma cruzi major cysteine proteinase, putative 0.0111 0.0724 0.0717
Chlamydia trachomatis DNA gyrase subunit B 0.0008 0.0011 0.0093
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0008 0.0011 0.001
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0007 0.0003 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.2004 0.5578
Mycobacterium tuberculosis Probable conserved lipoprotein 0.001 0.0025 0.0627
Echinococcus granulosus FTZ F1 alpha 0.0103 0.0668 0.0667
Leishmania major hypothetical protein, conserved 0.0008 0.0008 0.0014
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0034 0.0194 0.4857
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0724 0.2013
Echinococcus granulosus mitogen activated protein kinase 3 0.0079 0.0502 0.0501
Mycobacterium ulcerans regulatory protein 0.0008 0.0008 0.0067
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0008 0.0011 0.0024

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 17 % Percent inhibition of SRS-A release in vitro at a dose of 10 microM in guinea pig ChEMBL. 2903244

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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