Detailed information for compound 1527378

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 240.256 | Formula: C11H16N2O4
  • H donors: 1 H acceptors: 2 LogP: 1.45 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc([N+](=O)[O-])c(cc1C[C@H](N)C)OC
  • InChi: 1S/C11H16N2O4/c1-7(12)4-8-5-11(17-3)9(13(14)15)6-10(8)16-2/h5-7H,4,12H2,1-3H3/t7-/m1/s1
  • InChiKey: JQJRESSXOVAECC-SSDOTTSWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Serotonin 1 (5-HT1) receptor Starlite/ChEMBL References
Rattus norvegicus Serotonin 2 (5-HT2) receptor Starlite/ChEMBL References
Rattus norvegicus Serotonin (5-HT) receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Serotonin (5-HT) receptor   386 aa 381 aa 30.2 %
Echinococcus granulosus g protein coupled receptor Serotonin 2 (5-HT2) receptor   460 aa 412 aa 19.7 %
Echinococcus granulosus thyrotropin releasing hormone receptor Serotonin (5-HT) receptor   386 aa 355 aa 24.2 %
Echinococcus granulosus dro:myosuppressin receptor Serotonin (5-HT) receptor   386 aa 349 aa 18.6 %
Onchocerca volvulus Serotonin 1 (5-HT1) receptor   366 aa 358 aa 22.3 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Serotonin 1 (5-HT1) receptor   366 aa 378 aa 27.5 %
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Serotonin (5-HT) receptor   386 aa 363 aa 24.0 %
Echinococcus granulosus orexin receptor type 2 Serotonin (5-HT) receptor   386 aa 328 aa 22.3 %
Schistosoma mansoni amine GPCR Serotonin (5-HT) receptor   386 aa 392 aa 26.0 %
Onchocerca volvulus E3 ubiquitin-protein ligase rpm-1 homolog Serotonin 1 (5-HT1) receptor   366 aa 324 aa 21.9 %
Loa Loa (eye worm) hypothetical protein Serotonin 2 (5-HT2) receptor   460 aa 417 aa 21.3 %
Onchocerca volvulus Serotonin 1 (5-HT1) receptor   366 aa 356 aa 30.9 %
Echinococcus multilocularis g protein coupled receptor Serotonin 1 (5-HT1) receptor   366 aa 371 aa 20.2 %
Onchocerca volvulus Serotonin 1 (5-HT1) receptor   366 aa 327 aa 20.8 %
Onchocerca volvulus 26S proteasome non-ATPase regulatory subunit 1 homolog Serotonin (5-HT) receptor   386 aa 371 aa 26.1 %
Echinococcus multilocularis orexin receptor type 2 Serotonin (5-HT) receptor   386 aa 328 aa 22.9 %
Onchocerca volvulus Phospholipase d-related homolog Serotonin (5-HT) receptor   386 aa 350 aa 18.6 %
Schistosoma japonicum ko:K04207 neuropeptide Y receptor Y5, putative Serotonin (5-HT) receptor   386 aa 320 aa 23.1 %
Echinococcus granulosus g protein coupled receptor Serotonin 2 (5-HT2) receptor   460 aa 409 aa 21.8 %
Echinococcus multilocularis g protein coupled receptor Serotonin 2 (5-HT2) receptor   460 aa 409 aa 21.5 %
Echinococcus multilocularis neuropeptides capa receptor Serotonin 2 (5-HT2) receptor   460 aa 408 aa 20.8 %
Schistosoma japonicum ko:K04134 cholinergic receptor, invertebrate, putative Serotonin (5-HT) receptor   386 aa 331 aa 30.8 %
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Serotonin (5-HT) receptor   386 aa 310 aa 21.6 %
Echinococcus granulosus neuropeptide receptor Serotonin (5-HT) receptor   386 aa 331 aa 21.8 %
Echinococcus multilocularis serotonin receptor Serotonin (5-HT) receptor   386 aa 393 aa 32.3 %
Onchocerca volvulus Forkhead box protein biniou homolog Serotonin (5-HT) receptor   386 aa 333 aa 21.3 %
Loa Loa (eye worm) hypothetical protein Serotonin 1 (5-HT1) receptor   366 aa 331 aa 22.4 %
Echinococcus multilocularis g protein coupled receptor Serotonin 2 (5-HT2) receptor   460 aa 412 aa 19.9 %
Echinococcus multilocularis somatostatin receptor Serotonin 1 (5-HT1) receptor   366 aa 299 aa 19.1 %
Brugia malayi GnHR receptor homolog Serotonin (5-HT) receptor   386 aa 335 aa 21.8 %
Echinococcus multilocularis dro:myosuppressin receptor Serotonin (5-HT) receptor   386 aa 349 aa 18.6 %
Brugia malayi sulfakinin receptor protein Serotonin (5-HT) receptor   386 aa 344 aa 23.3 %
Onchocerca volvulus Serotonin (5-HT) receptor   386 aa 363 aa 34.4 %
Schistosoma mansoni adenoreceptor Serotonin 1 (5-HT1) receptor   366 aa 341 aa 29.9 %
Onchocerca volvulus Serotonin (5-HT) receptor   386 aa 368 aa 20.7 %
Onchocerca volvulus Serotonin 1 (5-HT1) receptor   366 aa 341 aa 20.5 %
Echinococcus multilocularis serotonin receptor Serotonin 1 (5-HT1) receptor   366 aa 413 aa 24.5 %
Schistosoma japonicum ko:K04255 opsin 4 (melanopsin), putative Serotonin (5-HT) receptor   386 aa 359 aa 22.0 %
Loa Loa (eye worm) neuropeptide F receptor Serotonin 1 (5-HT1) receptor   366 aa 337 aa 22.8 %
Echinococcus multilocularis neuropeptide receptor Serotonin (5-HT) receptor   386 aa 331 aa 21.4 %
Echinococcus multilocularis rhodopsin orphan GPCR Serotonin 1 (5-HT1) receptor   366 aa 335 aa 20.3 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Serotonin 2 (5-HT2) receptor   460 aa 405 aa 31.1 %
Echinococcus granulosus biogenic amine 5HT receptor Serotonin 1 (5-HT1) receptor   366 aa 403 aa 34.0 %
Brugia malayi Serotonin/octopamine receptor family protein 7 Serotonin (5-HT) receptor   386 aa 355 aa 34.6 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Serotonin (5-HT) receptor   386 aa 332 aa 21.7 %
Onchocerca volvulus Serotonin 1 (5-HT1) receptor   366 aa 410 aa 24.1 %
Onchocerca volvulus Serotonin (5-HT) receptor   386 aa 338 aa 34.0 %
Onchocerca volvulus Mitochondrial inner membrane protein homolog Serotonin (5-HT) receptor   386 aa 333 aa 37.2 %
Loa Loa (eye worm) hypothetical protein Serotonin 1 (5-HT1) receptor   366 aa 350 aa 35.7 %
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor Serotonin (5-HT) receptor   386 aa 337 aa 34.7 %
Schistosoma mansoni biogenic amine (5HT) receptor Serotonin (5-HT) receptor   386 aa 344 aa 33.4 %
Onchocerca volvulus Serotonin (5-HT) receptor   386 aa 354 aa 20.1 %
Echinococcus multilocularis thyrotropin releasing hormone receptor Serotonin (5-HT) receptor   386 aa 355 aa 24.2 %
Schistosoma mansoni dro/myosuppressin receptor Serotonin (5-HT) receptor   386 aa 334 aa 24.0 %
Onchocerca volvulus Serotonin 1 (5-HT1) receptor   366 aa 360 aa 21.4 %
Onchocerca volvulus Serotonin (5-HT) receptor   386 aa 333 aa 21.0 %
Echinococcus granulosus somatostatin receptor Serotonin 1 (5-HT1) receptor   366 aa 297 aa 19.9 %
Echinococcus granulosus rhodopsin orphan GPCR Serotonin 1 (5-HT1) receptor   366 aa 335 aa 20.6 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Serotonin 2 (5-HT2) receptor   460 aa 427 aa 28.3 %
Schistosoma japonicum Rhodopsin, putative Serotonin 1 (5-HT1) receptor   366 aa 364 aa 20.1 %
Schistosoma japonicum ko:K04165 Oamb gene product from transcript, putative Serotonin 1 (5-HT1) receptor   366 aa 331 aa 26.0 %
Schistosoma japonicum ko:K04153 5-hydroxytryptamine (serotonin) receptor 1A, putative Serotonin 1 (5-HT1) receptor   366 aa 325 aa 32.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum DNA topoisomerase 3, putative 0.0063 0.0069 0.0053
Loa Loa (eye worm) hypothetical protein 0.0097 0.029 0.045
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0151 0.0634 0.0619
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0068 0.0101 0.0197
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.092 0.3829
Echinococcus granulosus cyclin dependent kinase 1 0.0132 0.0509 0.0732
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0504 0.2893 0.4478
Loa Loa (eye worm) hypothetical protein 0.0399 0.222 0.3437
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0093 0.0262 0.1023
Brugia malayi Protein kinase domain containing protein 0.0258 0.1316 0.2038
Trypanosoma cruzi prenyl protein specific carboxyl methyltransferase, putative 0.012 0.0435 0.1059
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0136 0.0534 0.0826
Schistosoma mansoni GTPase activating protein 0.0056 0.0027 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0384 0.0746
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0443 0.25 0.4322
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0243 0.1223 0.1893
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0056 0.0027 0.0052
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0374 0.1514
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0095 0.0272 0.047
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0857 0.5145 1
Leishmania major protein kinase, putative 0.0111 0.0379 0.0918
Entamoeba histolytica protein kinase, putative 0.032 0.1712 0.7067
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0136 0.0534 0.1309
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0174 0.0782 0.1353
Schistosoma mansoni tyrosine kinase 0.0232 0.1152 0.224
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1062 0.6461 1
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0143 0.058 0.1128
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.0296 0.1166
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0098 0.0295 0.1161
Trichomonas vaginalis AGC family protein kinase 0.0098 0.0295 0.118
Schistosoma mansoni serine/threonine protein kinase 0.0396 0.2199 0.4274
Brugia malayi Protein kinase domain containing protein 0.0069 0.0108 0.0167
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0056 0.0027 0.0046
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0197 0.0926 0.1332
Echinococcus multilocularis nervana 2 0.014 0.0561 0.0971
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0111 0.0379 0.0363
Echinococcus granulosus Glutaredoxin protein 5 0.014 0.0561 0.0807
Loa Loa (eye worm) AGC/AKT protein kinase 0.032 0.1712 0.2649
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0488 0.2787 0.4007
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0125 0.0467 0.1141
Echinococcus granulosus transcription factor btf3 0.0076 0.0152 0.0219
Plasmodium vivax calcium-dependent protein kinase, putative 0.0111 0.0379 0.0363
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0396 0.2199 0.3404
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0068 0.0101 0.0215
Brugia malayi intracellular kinase 0.0143 0.058 0.0898
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.1115 0.2167
Echinococcus granulosus tyrosine protein kinase Src42A 0.0158 0.0677 0.0973
Schistosoma mansoni tensin 0.0056 0.0027 0.0052
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0171 0.0761 0.1884
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0336 0.1815 0.3139
Toxoplasma gondii CMGC kinase, CK2 family 0.011 0.0374 0.0358
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0017 0.0032
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0857 0.5145 0.8895
Echinococcus granulosus serine:threonine kinase SAD 1 0.0098 0.0296 0.0426
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0103 0.0329 0.0639
Entamoeba histolytica protein kinase, putative 0.0141 0.0567 0.2295
Entamoeba histolytica protein kinase, putative 0.0079 0.017 0.0638
Echinococcus multilocularis insulin receptor 0.0443 0.2501 0.4323
Schistosoma mansoni vam6/vps39 related 0.0098 0.0293 0.0569
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0063 0.0069 0.0119
Mycobacterium ulcerans hypothetical protein 0.0115 0.0402 0.04
Giardia lamblia Aurora kinase 0.0098 0.0295 0.1276
Brugia malayi hypothetical protein 0.0115 0.04 0.0619
Trypanosoma brucei protein kinase, putative 0.0076 0.0152 0.0343
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0655 0.2706
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0763 0.1483
Echinococcus granulosus casein kinase I alpha 0.012 0.0435 0.0626
Entamoeba histolytica casein kinase, putative 0.011 0.0374 0.1489
Entamoeba histolytica prolyl oligopeptidase family protein 0.0068 0.0101 0.0354
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0239 0.0943
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0249 0.1257 0.2172
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.026 0.1328 0.2055
Loa Loa (eye worm) TOPoisomerase family member 0.0423 0.2375 0.3676
Brugia malayi prolyl oligopeptidase family protein 0.0857 0.5145 0.7964
Echinococcus granulosus CDC7 cell division cycle 7 0.0099 0.0299 0.043
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0056 0.0027 0.0046
Brugia malayi Furin-like cysteine rich region family protein 0.0512 0.2938 0.4548
Schistosoma mansoni tensin 0.0056 0.0027 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0152 0.0576
Plasmodium vivax basic transcription factor 3b, putative 0.0076 0.0152 0.0136
Onchocerca volvulus 0.0097 0.029 0.0515
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0013 0.0021
Brugia malayi Protein kinase domain containing protein 0.0097 0.029 0.045
Plasmodium vivax serine/threonine kinase-1, putative 0.0171 0.0761 0.0745
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0161 0.0697 0.1205
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0136 0.0534 0.1309
Entamoeba histolytica protein kinase, putative 0.0136 0.0534 0.2156
Echinococcus multilocularis PAK box P21 Rho binding 0.007 0.0115 0.0199
Trypanosoma brucei oligopeptidase b 0.0068 0.0101 0.0215
Schistosoma mansoni kinase 0.027 0.1391 0.2703
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0068 0.0101 0.0215
Trichomonas vaginalis AGC family protein kinase 0.032 0.1712 0.7187
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0056 0.0027 0.0038
Giardia lamblia Kinase, NEK 0.0151 0.0634 0.2831
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0374 0.1514
Brugia malayi p70 ribosomal S6 kinase beta 0.0311 0.1657 0.2565
Echinococcus multilocularis prolyl endopeptidase 0.0068 0.0101 0.0175
Loa Loa (eye worm) hypothetical protein 0.0056 0.0027 0.0041
Echinococcus granulosus protein kinase c epsilon type 0.022 0.1074 0.1545
Echinococcus granulosus protein kinase C gamma type 0.0218 0.1059 0.1522
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0089 0.0236 0.0219
Brugia malayi Protein kinase domain containing protein 0.0132 0.0509 0.0788
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0379 0.0737
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0068 0.0101 0.0354
Echinococcus granulosus snurportin 1 0.0334 0.1805 0.2596
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.029 0.045
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0098 0.0296 0.0708
Brugia malayi prolyl oligopeptidase family protein 0.0068 0.0101 0.0157
Entamoeba histolytica protein kinase, putative 0.0154 0.0655 0.266
Giardia lamblia Kinase, CDC7 0.0099 0.0299 0.1294
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0125 0.0467 0.1141
Trypanosoma brucei DNA topoisomerase IA, putative 0.0063 0.0069 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.0467 0.0908
Echinococcus multilocularis cyclin dependent kinase 1 0.0132 0.0509 0.088
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0068 0.0101 0.0099
Echinococcus multilocularis titin 0.0066 0.0089 0.0153
Schistosoma mansoni SH2A 0.0056 0.0027 0.0052
Trichomonas vaginalis AGC family protein kinase 0.0151 0.0634 0.2619
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.014 0.0561 0.0971
Loa Loa (eye worm) hypothetical protein 0.0098 0.0293 0.0453
Giardia lamblia Kinase, CMGC GSK 0.0143 0.058 0.2583
Echinococcus multilocularis geminin 0.056 0.325 0.562
Onchocerca volvulus 0.0365 0.2001 0.3857
Onchocerca volvulus 0.0086 0.0215 0.0367
Plasmodium vivax hypothetical protein, conserved 0.0068 0.0101 0.0085
Schistosoma mansoni tyrosine kinase 0.0443 0.2501 0.486
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0151 0.0634 0.0619
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0098 0.0296 0.0512
Onchocerca volvulus 0.0099 0.0299 0.0532
Giardia lamblia Kinase, CMGC GSK 0.0143 0.058 0.2583
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.012 0.0435 0.1773
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0132 0.0514 0.0739
Brugia malayi Protein kinase domain containing protein 0.0504 0.2893 0.4478
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0092 0.0255 0.0604
Brugia malayi Stress-activated protein kinase jnk-1 0.0296 0.1561 0.2416
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0404 0.0785
Echinococcus granulosus suppressor of cytokine signaling 6 0.0056 0.0027 0.0038
Echinococcus granulosus mitogen activated protein kinase 11 0.0177 0.08 0.1151
Trypanosoma brucei aurora B kinase 0.0098 0.0295 0.0705
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0132 0.0514 0.0888
Echinococcus granulosus twitchin 0.0153 0.0648 0.0932
Brugia malayi Protein kinase domain containing protein 0.0089 0.0239 0.037
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0056 0.0027 0.0041
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0063 0.0069 0.0134
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0111 0.0379 0.0545
Giardia lamblia Kinase, CMGC MAPK 0.0092 0.0255 0.1094
Echinococcus granulosus geminin 0.056 0.325 0.4673
Loa Loa (eye worm) hypothetical protein 0.0136 0.054 0.0835
Leishmania major DNA topoisomerase III, putative 0.0063 0.0069 0.0133
Brugia malayi SH2 domain containing protein 0.0056 0.0027 0.0041
Echinococcus multilocularis casein kinase I delta 0.012 0.0435 0.0753
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0013 0.0021
Brugia malayi SH2 domain containing protein 0.0441 0.2484 0.3845
Trichomonas vaginalis CK1 family protein kinase 0.012 0.0435 0.1776
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0092 0.0253 0.0391
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0094 0.027 0.0526
Trypanosoma cruzi p21-activated kinase 3, putative 0.0059 0.0045 0.0072
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0161 0.0697 0.1002
Schistosoma mansoni protein kinase 0.0215 0.1044 0.2029
Schistosoma mansoni tyrosine kinase 0.0355 0.1935 0.3761
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0132 0.0509 0.0493
Echinococcus multilocularis 0.0056 0.0027 0.0046
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0441 0.2484 0.4295
Brugia malayi P38 map kinase family protein 2 0.0177 0.08 0.1239
Brugia malayi SRC-1 0.0232 0.1152 0.1784
Entamoeba histolytica transcription factor BTF3, putative 0.0076 0.0152 0.0566
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0063 0.0069 0.0222
Echinococcus granulosus serine:threonine protein kinase 0.008 0.0182 0.0261
Echinococcus multilocularis SHC transforming protein 3 0.0056 0.0027 0.0046
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0098 0.0295 0.051
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.0467 0.0908
Brugia malayi Protein kinase domain containing protein 0.0097 0.029 0.045
Schistosoma mansoni serine/threonine protein kinase 0.022 0.1074 0.2088
Trichomonas vaginalis STE family protein kinase 0.0151 0.0634 0.2619
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0296 0.0576
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0207 0.0993 0.1537
Entamoeba histolytica PH domain containing protein kinase, putative 0.0134 0.0522 0.2106
Trypanosoma cruzi casein kinase, putative 0.012 0.0435 0.1061
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0207 0.0993 0.1717
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0226 0.0888
Loa Loa (eye worm) hypothetical protein 0.0101 0.0314 0.0486
Echinococcus granulosus casein kinase I alpha 0.012 0.0435 0.0626
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0063 0.0069 0.0099
Onchocerca volvulus 0.0063 0.0069 0.0083
Giardia lamblia Kinase, AGC PKA 0.0125 0.0467 0.2065
Echinococcus granulosus serine:threonine protein kinase 0.008 0.0182 0.0261
Entamoeba histolytica DNA topoisomerase III, putative 0.0063 0.0069 0.0219
Leishmania major casein kinase II, putative 0.011 0.0374 0.0904
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0111 0.0379 0.0587
Echinococcus multilocularis mitogen activated protein kinase 14 0.0177 0.08 0.1384
Trypanosoma brucei prenyl protein specific carboxyl methyltransferase 0.012 0.0435 0.1059
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.1616 1 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0066 0.0088 0.0126
Toxoplasma gondii NAC domain-containing protein 0.0076 0.0152 0.0136
Loa Loa (eye worm) hypothetical protein 0.0056 0.0027 0.0041
Entamoeba histolytica protein kinase, putative 0.0098 0.0295 0.1161
Brugia malayi Protein kinase domain containing protein 0.0171 0.0763 0.1181
Entamoeba histolytica protein kinase, putative 0.0111 0.0379 0.1511
Loa Loa (eye worm) hypothetical protein 0.006 0.0051 0.0079
Trypanosoma cruzi polo-like protein kinase, putative 0.0196 0.092 0.2286
Echinococcus multilocularis Glutaredoxin protein 5 0.014 0.0561 0.0971
Brugia malayi hypothetical protein 0.0064 0.0075 0.0117
Schistosoma mansoni atypical protein kinase C 0.0319 0.1709 0.3321
Giardia lamblia Kinase, STE STE20 0.0095 0.0272 0.117
Loa Loa (eye worm) hypothetical protein 0.0081 0.0183 0.0283
Entamoeba histolytica hypothetical protein 0.0076 0.0152 0.0566
Schistosoma mansoni shc transforming protein 0.0056 0.0027 0.0052
Onchocerca volvulus 0.0157 0.0671 0.1258
Brugia malayi Hr1 repeat family protein 0.0318 0.17 0.2632
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0232 0.1152 0.1992
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0177 0.08 0.1985
Echinococcus multilocularis mitogen activated protein kinase 11 0.0177 0.08 0.1384
Echinococcus granulosus epidermal growth factor receptor 0.0512 0.2938 0.4225
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0226 0.0888
Echinococcus granulosus SH2 domain containing protein 7 0.0056 0.0027 0.0038
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0091 0.0248 0.0963
Entamoeba histolytica cell division protein kinase 2, putative 0.0132 0.0509 0.2052
Loa Loa (eye worm) TK/ROR protein kinase 0.0066 0.0088 0.0136
Mycobacterium leprae Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0764 0.455 1
Trypanosoma cruzi prolyl endopeptidase 0.0068 0.0101 0.0215
Brugia malayi Immunoglobulin I-set domain containing protein 0.0055 0.0019 0.003
Entamoeba histolytica protein kinase, putative 0.0091 0.0251 0.0976
Loa Loa (eye worm) hypothetical protein 0.0064 0.0075 0.0117
Echinococcus granulosus growth factor receptor bound protein 2 0.0094 0.0267 0.0384
Schistosoma mansoni nck2/grb4 0.0092 0.0253 0.0491
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0098 0.0296 0.0708
Loa Loa (eye worm) hypothetical protein 0.0111 0.0379 0.0587
Leishmania major DNA topoisomerase ii 0.0361 0.1973 0.4954
Onchocerca volvulus Serine\/threonine kinase homolog 0.0183 0.0836 0.1582
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0045 0.0088
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0111 0.0379 0.0545
Loa Loa (eye worm) hypothetical protein 0.0133 0.0518 0.0802
Loa Loa (eye worm) hypothetical protein 0.0161 0.07 0.1083
Echinococcus multilocularis 0.0144 0.0587 0.1015
Loa Loa (eye worm) hypothetical protein 0.0159 0.0684 0.1059
Echinococcus multilocularis expressed conserved protein 0.0149 0.0623 0.1077
Echinococcus multilocularis serine:threonine protein kinase 3 0.0288 0.1507 0.2605
Trypanosoma cruzi casein kinase, putative 0.012 0.0435 0.1061
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0111 0.0379 0.0587
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0068 0.0101 0.0085
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0091 0.0251 0.0235
Loa Loa (eye worm) hypothetical protein 0.0218 0.1061 0.1643
Loa Loa (eye worm) TK protein kinase 0.0197 0.0926 0.1434
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.011 0.0374 0.0358
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0311 0.1657 0.2565
Schistosoma mansoni hypothetical protein 0.0056 0.0027 0.0052
Loa Loa (eye worm) hypothetical protein 0.0159 0.0684 0.1059
Schistosoma mansoni protein kinase 0.0076 0.0152 0.0295
Loa Loa (eye worm) hypothetical protein 0.0068 0.0101 0.0157
Schistosoma mansoni DNA topoisomerase II 0.0423 0.2375 0.4616
Brugia malayi SH2 domain containing protein 0.0097 0.029 0.045
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0103 0.0329 0.0509
Onchocerca volvulus 0.0097 0.029 0.0515
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.0467 0.0908
Plasmodium falciparum protein-S-isoprenylcysteine O-methyltransferase, putative 0.012 0.0435 0.0419
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0197 0.0926 0.1602
Brugia malayi serine/threonine-protein kinase plk-2 0.0196 0.092 0.1423
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0295 0.0573
Echinococcus granulosus casein kinase I delta 0.012 0.0435 0.0626
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0423 0.2375 0.3415
Echinococcus granulosus serine:threonine protein kinase 3 0.0288 0.1507 0.2167
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0471 0.2677 0.2665
Giardia lamblia Kinase, CMGC DYRK 0.0154 0.0655 0.2924
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0796 0.4756 0.4719
Trypanosoma cruzi DNA topoisomerase II, putative 0.0361 0.1973 0.4954
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0288 0.1509 0.3779
Schistosoma mansoni hypothetical protein 0.056 0.325 0.6317
Trypanosoma cruzi casein kinase, putative 0.012 0.0435 0.1061
Brugia malayi Tyrosine-protein kinase abl-1 0.0222 0.109 0.1687
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0068 0.0101 0.0215
Plasmodium vivax DNA gyrase subunit A, putative 0.1616 1 1
Entamoeba histolytica hypothetical protein 0.0136 0.0534 0.2156
Trypanosoma cruzi cdc2-related kinase 1 0.0132 0.0509 0.1247
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.012 0.0435 0.0674
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0063 0.0069 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0404 0.0785
Schistosoma mansoni hypothetical protein 0.0098 0.0293 0.0569
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0697 0.1355
Echinococcus granulosus expressed conserved protein 0.0056 0.0027 0.0038
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0056 0.0027 0.0046
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0265 0.1365 0.1962
Entamoeba histolytica prenyl cysteine carboxyl methyltransferase, putative 0.012 0.0435 0.1744
Mycobacterium ulcerans DNA topoisomerase I 0.0063 0.0069 0.0067
Trypanosoma cruzi DNA topoisomerase III, putative 0.0063 0.0069 0.0133
Echinococcus multilocularis acylamino acid releasing enzyme 0.0068 0.0101 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0068 0.0101 0.0215
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Schistosoma mansoni protein kinase 0.0488 0.2787 0.5418
Trichomonas vaginalis CAMK family protein kinase 0.0208 0.0998 0.416
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.029 0.045
Loa Loa (eye worm) hypothetical protein 0.0056 0.0027 0.0041
Brugia malayi prolyl oligopeptidase family protein 0.0068 0.0101 0.0157
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.012 0.0435 0.0674
Brugia malayi tRNA modification GTPase TrmE family protein 0.0056 0.0027 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0691 0.1343
Echinococcus granulosus titin 0.0066 0.0089 0.0127
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0255 0.1012
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0239 0.0943
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0174 0.0782 0.1939
Echinococcus multilocularis rho GTPase activating protein 20 0.0063 0.0069 0.0119
Entamoeba histolytica protein kinase domain containing protein 0.0143 0.058 0.235
Entamoeba histolytica protein kinase, putative 0.0089 0.0239 0.0927
Leishmania major protein kinase, putative 0.0171 0.0761 0.1884
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0183 0.0836 0.1446
Schistosoma mansoni tyrosine kinase 0.0276 0.1431 0.2781
Echinococcus multilocularis netrin receptor unc 5 0.0055 0.0019 0.0033
Onchocerca volvulus 0.007 0.0114 0.0171
Schistosoma mansoni tyrosine kinase 0.0355 0.1935 0.3761
Brugia malayi hypothetical protein 0.0249 0.1257 0.1945
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0091 0.0251 0.0593
Echinococcus multilocularis casein kinase I alpha 0.012 0.0435 0.0753
Loa Loa (eye worm) hypothetical protein 0.0098 0.0293 0.0453
Echinococcus granulosus neuroglian 0.0119 0.0427 0.0614
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0171 0.0763 0.1097
Mycobacterium tuberculosis Probable peptidase 0.0068 0.0101 0.0099
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0255 0.1012
Brugia malayi Temporarily assigned gene name protein 59 0.0098 0.0293 0.0453
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0063 0.0069 0.0222
Schistosoma mansoni hypothetical protein 0.0334 0.1805 0.3509
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.1361 0.2645
Trichomonas vaginalis AGC family protein kinase 0.0098 0.0295 0.118
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Trypanosoma cruzi casein kinase, putative 0.012 0.0435 0.1061
Brugia malayi hypothetical protein 0.0097 0.029 0.045
Trichomonas vaginalis STE family protein kinase 0.0095 0.0272 0.1082
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0086 0.0215 0.0501
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0763 0.1483
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0676 0.3988 0.6173
Schistosoma mansoni tyrosine kinase 0.0339 0.1835 0.3567
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.029 0.045
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.1361 0.2645
Schistosoma mansoni serine/threonine kinase 0.0171 0.0763 0.1483
Schistosoma mansoni cell adhesion molecule 0.0122 0.0446 0.0867
Leishmania major protein kinase A catalytic subunit isoform 1 0.0125 0.0467 0.1141
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0196 0.092 0.1322
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.1616 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.092 0.3829
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0111 0.0379 0.0363
Echinococcus multilocularis signal transduction protein lnk realted 0.0056 0.0027 0.0046
Trichomonas vaginalis AGC family protein kinase 0.032 0.1712 0.7187
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0171 0.0761 0.1884
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0655 0.2706
Schistosoma mansoni tyrosine kinase 0.0512 0.2938 0.5711
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0063 0.0069 0.0053
Echinococcus multilocularis Immunoglobulin 0.0094 0.027 0.0468
Trichomonas vaginalis AGC family protein kinase 0.0098 0.0295 0.118
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.012 0.0435 0.0674
Echinococcus granulosus tyrosine protein kinase Fyn 0.0232 0.1152 0.1657
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0115 0.0403 0.0579
Entamoeba histolytica protein kinase, putative 0.0171 0.0763 0.3111
Loa Loa (eye worm) hypothetical protein 0.0092 0.0253 0.0391
Leishmania major protein kinase A catalytic subunit 0.0125 0.0467 0.1141
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0089 0.0236 0.0219
Loa Loa (eye worm) CDC7 protein kinase 0.0099 0.0299 0.0463
Echinococcus granulosus serine threonine protein kinase nrc 0.0174 0.0782 0.1125
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.1167 0.2267
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0232 0.1152 0.1992
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0288 0.1509 0.2609
Schistosoma mansoni serine/threonine protein kinase 0.0296 0.1561 0.3033
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.092 0.3829
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0288 0.1509 0.3779
Entamoeba histolytica hypothetical protein 0.0115 0.04 0.1598
Trypanosoma cruzi DNA topoisomerase III, putative 0.0063 0.0069 0.0133
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0125 0.0467 0.1141
Loa Loa (eye worm) hypothetical protein 0.0064 0.0075 0.0117
Loa Loa (eye worm) casein kinase 0.0204 0.0971 0.1502
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.092 0.3829
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.029 0.045
Trypanosoma brucei Casein kinase II 0.011 0.0374 0.0904
Echinococcus granulosus dual specificity 0.0136 0.0534 0.0767
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0111 0.0379 0.0587
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.029 0.045
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0132 0.0509 0.0788
Brugia malayi Protein kinase domain containing protein 0.0238 0.1192 0.1844
Mycobacterium ulcerans DNA gyrase subunit A 0.1616 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0299 0.0581
Echinococcus granulosus tyrosine protein kinase ABL1 0.0332 0.179 0.2574
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0063 0.0069 0.0134
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0059 0.0045 0.007
Trichomonas vaginalis AGC family protein kinase 0.032 0.1712 0.7187
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.045 0.2544 0.4399
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0171 0.0761 0.1884
Trypanosoma cruzi DNA topoisomerase II, putative 0.0361 0.1973 0.4954
Brugia malayi serine/threonine-protein kinase 6 0.0098 0.0295 0.0457
Schistosoma mansoni serine/threonine kinase 0.0208 0.0998 0.1939
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0125 0.0467 0.0808
Leishmania major protein kinase A catalytic subunit isoform 2 0.0125 0.0467 0.1141
Echinococcus granulosus casein kinase ii subunit alpha 0.011 0.0374 0.0537
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0076 0.0152 0.0343
Brugia malayi Protein kinase domain containing protein 0.008 0.0182 0.0281
Entamoeba histolytica PH domain containing protein kinase, putative 0.0183 0.0837 0.342
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0095 0.0272 0.047
Trypanosoma cruzi cdc2-related kinase 3 0.0132 0.0509 0.1247
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0224 0.1101 0.1705
Entamoeba histolytica protein kinase domain containing protein 0.0076 0.0152 0.0564
Plasmodium falciparum glycogen synthase kinase 3 0.0143 0.058 0.0565
Trypanosoma brucei DNA topoisomerase III, putative 0.0063 0.0069 0.0133
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0232 0.1152 0.1992
Schistosoma mansoni titin 0.0066 0.0089 0.0172
Echinococcus multilocularis neuroglian 0.0119 0.0427 0.0739
Giardia lamblia Isoprenylcysteine carboxyl methyltransferase 0.012 0.0435 0.1917
Brugia malayi serine/threonine-protein kinase PAK 7 0.026 0.1328 0.2055
Loa Loa (eye worm) hypothetical protein 0.0157 0.0671 0.1038
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0068 0.0101 0.0354
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.022 0.1074 0.1663
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0092 0.0255 0.0604
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0377 0.2075 0.3213
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0098 0.0293 0.0421
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0372 0.2046 0.3167
Trypanosoma brucei prolyl endopeptidase 0.0068 0.0101 0.0215
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0095 0.0272 0.047
Onchocerca volvulus 0.0097 0.029 0.0515
Echinococcus multilocularis serine threonine protein kinase 0.0218 0.1059 0.183
Plasmodium vivax DNA gyrase subunit B, putative 0.0796 0.4756 0.4747
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0296 0.0576
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0066 0.0088 0.0152
Trypanosoma cruzi casein kinase II, putative 0.011 0.0374 0.0904
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0288 0.1509 0.3779
Schistosoma mansoni serine/threonine-protein kinase 0.0183 0.0837 0.1627
Brugia malayi Temporarily assigned gene name protein 59 0.0146 0.06 0.0929
Leishmania major basic transcription factor 3a, putative 0.0076 0.0152 0.0344
Trichomonas vaginalis STE family protein kinase 0.0095 0.0272 0.1082
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0296 0.0576
Toxoplasma gondii hypothetical protein 0.0068 0.0101 0.0085
Trypanosoma cruzi aurora B kinase, putative 0.0098 0.0295 0.0705
Giardia lamblia Kinase, CK1 Casein kinase 0.012 0.0435 0.192
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0796 0.4756 0.4755
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0132 0.0509 0.0732
Echinococcus granulosus nuclear factor of activated T cells 5 0.0336 0.1815 0.261
Plasmodium vivax protein-S-isoprenylcysteine O-methyltransferase, putative 0.012 0.0435 0.0419
Brugia malayi serine/threonine protein kinase 6 0.0098 0.0295 0.0457
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0255 0.1012
Trichomonas vaginalis AGC family protein kinase 0.032 0.1712 0.7187
Toxoplasma gondii prolyl endopeptidase 0.0068 0.0101 0.0085
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Echinococcus granulosus roundabout 2 0.0146 0.0603 0.0867
Brugia malayi casein kinase I 0.012 0.0435 0.0674
Leishmania major protein kinase, putative 0.0076 0.0152 0.0343
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0836 0.1625
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.1616 1 1
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0215 0.1044 0.1616
Echinococcus multilocularis protein kinase shaggy 0.0143 0.058 0.1003
Echinococcus granulosus raf serine:threonine protein kinase 0.0089 0.0233 0.0336
Brugia malayi Protein kinase c protein 2 0.0128 0.0486 0.0753
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0296 0.1561 0.2698
Brugia malayi Immunoglobulin I-set domain containing protein 0.0057 0.0031 0.0048
Echinococcus granulosus casein kinase I alpha 0.012 0.0435 0.0626
Loa Loa (eye worm) hypothetical protein 0.0161 0.07 0.1083
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0234 0.1167 0.2017
Loa Loa (eye worm) TK/EPH protein kinase 0.0133 0.0521 0.0806
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0092 0.0255 0.0395
Brugia malayi Protein kinase domain containing protein 0.0091 0.0251 0.0388
Echinococcus granulosus casein kinase i 0.012 0.0435 0.0626
Trypanosoma cruzi transcription factor btf3, putative 0.0076 0.0152 0.0344
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0174 0.0782 0.1125
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.029 0.045
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.0496 0.0768
Plasmodium falciparum protein kinase, putative 0.0076 0.0152 0.0136
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0154 0.0655 0.1616
Onchocerca volvulus 0.0143 0.058 0.1082
Trypanosoma cruzi oligopeptidase b 0.0068 0.0101 0.0215
Echinococcus granulosus hypothetical protein 0.0056 0.0027 0.0038
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0097 0.029 0.1142
Schistosoma mansoni suppressor of cytokine signaling 0.0056 0.0027 0.0052
Brugia malayi Protein kinase domain containing protein 0.0224 0.1101 0.1705
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0509 0.0989
Echinococcus granulosus SH2 domain containing adapter protein F 0.0056 0.0027 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0435 0.0846
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.1257 0.2442
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.0299 0.1197
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0284 0.1481 0.2129
Schistosoma mansoni hypothetical protein 0.056 0.325 0.6317
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0125 0.0467 0.0451
Plasmodium falciparum calcium-dependent protein kinase 4 0.0111 0.0379 0.0363
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0396 0.2199 0.3404
Leishmania major protein kinase, putative 0.0098 0.0295 0.0705
Echinococcus multilocularis epidermal growth factor receptor 0.0355 0.1935 0.3345
Brugia malayi Egg laying defective protein 4 0.0149 0.0623 0.0964
Brugia malayi SH2 domain containing protein 0.0056 0.0027 0.0041
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0143 0.058 0.0898
Trichomonas vaginalis CAMK family protein kinase 0.008 0.0182 0.07
Brugia malayi Variant SH3 domain containing protein 0.0092 0.0253 0.0391
Echinococcus granulosus c src tyrosine kinase 0.0133 0.0516 0.0742
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0258 0.1316 0.2038
Echinococcus granulosus tyrosine protein kinase Fyn 0.0232 0.1152 0.1657
Schistosoma mansoni transcription factor btf3 0.0076 0.0152 0.0296
Schistosoma mansoni tyrosine kinase 0.0265 0.1365 0.2652
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0103 0.0329 0.0473
Echinococcus multilocularis ephrin type A receptor 4 A 0.0114 0.0394 0.0681
Echinococcus multilocularis dual specificity protein kinase clk2 0.0171 0.0761 0.1315
Plasmodium falciparum calcium-dependent protein kinase 2 0.0111 0.0379 0.0363
Loa Loa (eye worm) hypothetical protein 0.0056 0.0024 0.0038
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0068 0.0101 0.0215
Entamoeba histolytica prenyl cysteine carboxyl methyltransferase, putative 0.012 0.0435 0.1744
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0149 0.0623 0.0607
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0374 0.1514
Schistosoma mansoni serine/threonine protein kinase 0.0537 0.3099 0.6023
Brugia malayi protein kinase C II. 0.022 0.1074 0.1663
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0091 0.0246 0.0426
Loa Loa (eye worm) hypothetical protein 0.0092 0.0256 0.0397
Loa Loa (eye worm) hypothetical protein 0.0209 0.1002 0.1551
Trichomonas vaginalis AGC family protein kinase 0.0171 0.0763 0.3164
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0232 0.1152 0.1992
Loa Loa (eye worm) hypothetical protein 0.0101 0.0314 0.0486
Trypanosoma brucei cdc2-related kinase 3 0.0132 0.0509 0.1247
Entamoeba histolytica protein kinase, putative 0.0077 0.0162 0.0607
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0125 0.0467 0.0808
Trichomonas vaginalis AGC family protein kinase 0.0098 0.0295 0.118
Onchocerca volvulus 0.012 0.0435 0.0799
Echinococcus granulosus rho-associated protein kinase 1 0.0365 0.2001 0.2877
Entamoeba histolytica prolyl oligopeptidase family protein 0.0068 0.0101 0.0354
Giardia lamblia Kinase, STE STE20 0.0093 0.0262 0.1125
Trypanosoma cruzi cdc2-related kinase 1 0.0132 0.0509 0.1247
Schistosoma mansoni serine/threonine-protein kinase 0.0183 0.0837 0.1627
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0196 0.0921 0.1425
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0152 0.0576
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0161 0.0697 0.1205
Loa Loa (eye worm) hypothetical protein 0.0125 0.0467 0.0723
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0076 0.0152 0.0263
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0697 0.1355
Echinococcus multilocularis rac serine:threonine kinase 0.0183 0.0837 0.1447
Brugia malayi Protein kinase domain containing protein 0.0097 0.029 0.045
Plasmodium falciparum calcium-dependent protein kinase 1 0.0111 0.0379 0.0363
Schistosoma mansoni tyrosine kinase 0.0077 0.0158 0.0307
Leishmania major mitochondrial DNA topoisomerase II 0.0672 0.3966 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0081 0.0126
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0103 0.0329 0.0569
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0056 0.0027 0.0038
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0125 0.0467 0.1141
Loa Loa (eye worm) hypothetical protein 0.0131 0.0504 0.0781
Schistosoma mansoni tyrosine kinase 0.0443 0.2501 0.486
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.012 0.0435 0.1773
Loa Loa (eye worm) SH2 domain-containing protein 0.0056 0.0027 0.0041
Plasmodium vivax protein kinase Crk2 0.0132 0.0509 0.0493
Echinococcus multilocularis raf serine:threonine protein kinase 0.0089 0.0233 0.0404
Schistosoma mansoni tyrosine kinase 0.0133 0.0516 0.1004
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0177 0.08 0.1239
Giardia lamblia Kinase, CMGC CDK 0.0132 0.0509 0.2256
Leishmania major protein kinase, putative 0.0171 0.0761 0.1884
Brugia malayi Protein kinase domain containing protein 0.0136 0.0534 0.0826
Entamoeba histolytica protein kinase, putative 0.032 0.1712 0.7067
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0171 0.0761 0.0745
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0115 0.04 0.0691
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0258 0.1316 0.1893
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0059 0.0045 0.012
Echinococcus granulosus Immunoglobulin 0.0094 0.027 0.0389
Chlamydia trachomatis DNA gyrase subunit B 0.0796 0.4756 0.4719
Entamoeba histolytica serine/threonine protein kinase, putative 0.0196 0.092 0.3764
Echinococcus granulosus Vam6:Vps39 protein 0.0098 0.0293 0.0421
Brugia malayi Cam kinase protein 1 0.0111 0.0379 0.0587
Toxoplasma gondii AGC kinase 0.0125 0.0467 0.0451
Brugia malayi ephrin receptor 1 precursor 0.0075 0.0149 0.0231
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0224 0.1101 0.1583
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.029 0.045
Echinococcus multilocularis death associated protein kinase 1 0.0957 0.5784 1
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0243 0.1223 0.1893
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0115 0.04 0.0575
Trypanosoma brucei polo-like protein kinase 0.0196 0.092 0.2286
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0154 0.0655 0.1013
Brugia malayi DNA topoisomerase III 0.0063 0.0069 0.0107
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0137 0.0542 0.2227
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0288 0.1509 0.2933
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0111 0.0379 0.0545
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.092 0.1787
Trypanosoma cruzi oligopeptidase b 0.0068 0.0101 0.0215
Entamoeba histolytica protein kinase, putative 0.007 0.0115 0.041
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0296 0.1561 0.2416
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0177 0.08 0.1985
Plasmodium falciparum casein kinase 2, alpha subunit 0.011 0.0374 0.0358
Brugia malayi Protein kinase domain containing protein 0.0097 0.029 0.045
Entamoeba histolytica protein kinase domain containing protein 0.0154 0.0655 0.266
Brugia malayi Protein kinase domain containing protein 0.0208 0.0998 0.1544
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0056 0.0027 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.0365 0.2001 0.3889
Echinococcus multilocularis casein kinase i 0.012 0.0435 0.0753
Onchocerca volvulus Netrin receptor homolog 0.0059 0.0044 0.0034
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0056 0.0027 0.0038
Entamoeba histolytica protein kinase, putative 0.0143 0.058 0.235
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0224 0.1101 0.1904
Echinococcus granulosus NCK adaptor protein 0.0092 0.0253 0.0363
Trypanosoma cruzi prenyl protein specific carboxyl methyltransferase, putative 0.012 0.0435 0.1059
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0098 0.0293 0.0699
Echinococcus multilocularis serine:threonine protein kinase 0.008 0.0182 0.0314
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0509 0.0989
Brugia malayi beta-NAC-like protein 0.0076 0.0152 0.0236
Trypanosoma brucei prolyl oligopeptidase, putative 0.0068 0.0101 0.0215
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0068 0.0101 0.036
Brugia malayi Immunoglobulin I-set domain containing protein 0.0705 0.4179 0.6468
Onchocerca volvulus 0.0549 0.3179 0.616
Loa Loa (eye worm) hypothetical protein 0.0399 0.222 0.3437
Loa Loa (eye worm) hypothetical protein 0.0157 0.0671 0.1038
Trypanosoma cruzi transcription factor btf3, putative 0.0076 0.0152 0.0344
Echinococcus multilocularis 0.0136 0.054 0.0933
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0125 0.0467 0.0451
Loa Loa (eye worm) hypothetical protein 0.022 0.1075 0.1664
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0068 0.0101 0.0197
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0177 0.08 0.1985
Echinococcus multilocularis casein kinase ii subunit alpha 0.011 0.0374 0.0646
Loa Loa (eye worm) prolyl oligopeptidase 0.0068 0.0101 0.0157
Schistosoma mansoni hypothetical protein 0.0081 0.0183 0.0355
Schistosoma mansoni hypothetical protein 0.0115 0.04 0.0777
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0076 0.0152 0.0343
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0133 0.0516 0.1004
Brugia malayi Kinase associated domain 1 family protein 0.0081 0.0183 0.0283
Echinococcus multilocularis casein kinase I delta 0.012 0.0435 0.0753
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0111 0.0379 0.0363
Echinococcus multilocularis 0.012 0.0435 0.0752
Giardia lamblia Kinase, CMGC CDK 0.0132 0.0509 0.2256
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0226 0.1115 0.1726
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.092 0.3829
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0056 0.0027 0.0046
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0284 0.1481 0.256
Brugia malayi Protein kinase domain containing protein 0.0099 0.0299 0.0463
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0057 0.0031 0.0048
Schistosoma mansoni tensin 0.0056 0.0027 0.0052
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0063 0.0069 0.0099
Echinococcus granulosus X box binding protein 1 0.0313 0.1668 0.2399
Echinococcus multilocularis Immunoglobulin 0.0094 0.027 0.0468
Echinococcus multilocularis tyrosine protein kinase Blk 0.0197 0.0926 0.1602
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0482 0.1973
Trypanosoma brucei DNA topoisomerase III, putative 0.0063 0.0069 0.0133
Brugia malayi protein-S isoprenylcysteine O-methyltransferase, putative 0.012 0.0435 0.0673
Trichomonas vaginalis STE family protein kinase 0.007 0.0115 0.0417
Brugia malayi SH2 domain containing protein 0.0056 0.0027 0.0041
Brugia malayi protein-tyrosine kinase 0.0197 0.0926 0.1434
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0143 0.058 0.1427
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0152 0.0576
Plasmodium vivax serine/threonine protein kinase, putative 0.0091 0.0251 0.0235
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0655 0.2706
Echinococcus granulosus calcium dependent protein kinase 0.0077 0.0158 0.0227
Giardia lamblia Alanyl dipeptidyl peptidase 0.0068 0.0101 0.0389
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0125 0.0467 0.0808
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0093 0.0262 0.0621
Trichomonas vaginalis AGC family protein kinase 0.0171 0.0763 0.3164
Entamoeba histolytica cell division protein kinase 2, putative 0.0132 0.0509 0.2052
Trichomonas vaginalis AGC family protein kinase 0.018 0.0817 0.3396
Echinococcus granulosus prolyl endopeptidase 0.0068 0.0101 0.0146
Loa Loa (eye worm) hypothetical protein 0.0218 0.1061 0.1643
Schistosoma mansoni tyrosine kinase 0.0232 0.1152 0.224
Brugia malayi RhoGAP domain containing protein 0.0103 0.0329 0.0509
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0056 0.0027 0.0052
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0056 0.0027 0.0046
Brugia malayi Immunoglobulin I-set domain containing protein 0.0066 0.0089 0.0137
Brugia malayi protein kinase C3,putative 0.0176 0.079 0.1223
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0509 0.2087
Brugia malayi ribosomal protein S6 kinase alpha 3 0.013 0.0496 0.0768
Echinococcus granulosus expressed protein 0.0091 0.0251 0.036
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0396 0.2199 0.3802
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0239 0.0464
Echinococcus granulosus dual specificity 0.0154 0.0655 0.0941
Echinococcus granulosus dual specificity 0.0154 0.0655 0.0941
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0095 0.0272 0.0391
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0092 0.0253 0.0391
Echinococcus granulosus serine/threonine protein kinase 0.0183 0.0837 0.1203
Trypanosoma brucei cdc2-related kinase 1 0.0132 0.0509 0.1247
Brugia malayi cell division control protein 2 homolog 0.0132 0.0509 0.0788
Toxoplasma gondii AGC kinase 0.0311 0.1657 0.1643
Plasmodium falciparum serine/threonine protein kinase 0.0091 0.0251 0.0235
Brugia malayi Fes/CIP4 homology domain containing protein 0.0121 0.0442 0.0684
Onchocerca volvulus Huntingtin homolog 0.0133 0.0518 0.096
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0051 0.0145
Brugia malayi Variant SH3 domain containing protein 0.0103 0.0329 0.0509
Plasmodium falciparum DNA topoisomerase 2 0.0423 0.2375 0.2362
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0161 0.0697 0.1002
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0288 0.1507 0.2332
Schistosoma mansoni vesicular amine transporter 0.0094 0.027 0.0526
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0265 0.1365 0.2359
Brugia malayi Protein kinase domain containing protein 0.0204 0.0969 0.15
Trypanosoma cruzi casein kinase, delta isoform, putative 0.012 0.0435 0.1061
Toxoplasma gondii DNA topoisomerase family protein 0.0063 0.0069 0.0053
Entamoeba histolytica protein kinase domain containing protein 0.0136 0.0534 0.2156
Schistosoma mansoni protein kinase 0.0488 0.2787 0.5418
Loa Loa (eye worm) hypothetical protein 0.0056 0.0027 0.0041
Onchocerca volvulus Huntingtin homolog 0.0133 0.0518 0.096
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0077 0.0162 0.028
Echinococcus multilocularis protein kinase c epsilon type 0.022 0.1074 0.1857
Brugia malayi phosphoinositide-dependent protein kinase I 0.0089 0.0239 0.037
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0059 0.0045 0.0072
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0332 0.179 0.3095
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0092 0.0255 0.0239
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0127 0.0482 0.0693
Echinococcus granulosus activin receptor type 0.0076 0.0152 0.0218
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0125 0.0467 0.0672
Loa Loa (eye worm) TK protein kinase 0.029 0.1521 0.2355
Loa Loa (eye worm) hypothetical protein 0.0094 0.027 0.0419
Entamoeba histolytica protein kinase domain containing protein 0.011 0.0374 0.1489
Echinococcus granulosus nervana 2 0.014 0.0561 0.0807
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0796 0.4756 0.4719
Echinococcus multilocularis tensin 0.0056 0.0027 0.0046
Echinococcus granulosus tyrosine protein kinase Src64B 0.0232 0.1152 0.1657
Schistosoma mansoni serine/threonine protein kinase 0.0238 0.1192 0.2316
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0265 0.1361 0.2353
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0402 0.2239 0.4323
Echinococcus granulosus c-Jun N-terminal kinases 0.0296 0.1561 0.2244
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0488 0.2787 0.4819
Loa Loa (eye worm) hypothetical protein 0.0522 0.3003 0.4649
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0063 0.0069 0.0133
Brugia malayi Probable DNA topoisomerase II 0.0423 0.2375 0.3676
Echinococcus multilocularis calcium dependent protein kinase 0.0077 0.0158 0.0273
Loa Loa (eye worm) hypothetical protein 0.0056 0.0027 0.0041
Echinococcus multilocularis serine:threonine protein kinase 38 0.0171 0.0763 0.1319
Loa Loa (eye worm) DNA topoisomerase III 0.0063 0.0069 0.0107
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0158 0.0677 0.1171
Brugia malayi Protein kinase domain containing protein 0.1062 0.6461 1
Echinococcus multilocularis tyrosine protein kinase HCK 0.0141 0.0567 0.098
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0092 0.0253 0.0491
Onchocerca volvulus 0.0217 0.1057 0.2013
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0672 0.3966 1
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0098 0.0293 0.0506
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0013 0.0021
Entamoeba histolytica SH2 domain containing protein 0.0056 0.0027 0.0042
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0265 0.1363 0.2888
Schistosoma mansoni netrin receptor unc5 0.0055 0.0019 0.0037
Echinococcus granulosus insulin growth factor 1 receptor beta 0.045 0.2544 0.3658
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0143 0.058 0.1003
Schistosoma mansoni tyrosine kinase 0.0313 0.1671 0.3248
Brugia malayi Tensin 0.0056 0.0027 0.0041
Brugia malayi DNA topoisomerase III beta-1 0.0063 0.0069 0.0107
Echinococcus multilocularis tyrosine kinase 0.0097 0.029 0.0502
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0066 0.009 0.014
Leishmania major DNA topoisomerase III, putative 0.0063 0.0069 0.0133
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0125 0.0467 0.1141
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0111 0.0379 0.0655
Loa Loa (eye worm) TK/ABL protein kinase 0.0332 0.179 0.2771
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0143 0.058 0.0898
Trichomonas vaginalis CK1 family protein kinase 0.012 0.0435 0.1776
Loa Loa (eye worm) hypothetical protein 0.0234 0.1162 0.1798
Brugia malayi SH2 domain containing protein 0.0056 0.0027 0.0041
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0207 0.0993 0.1537
Loa Loa (eye worm) AGC/PKA protein kinase 0.0125 0.0467 0.0723
Giardia lamblia Kinase, PLK 0.0196 0.092 0.4138
Echinococcus granulosus insulin receptor 0.0443 0.2501 0.3595
Brugia malayi prolyl oligopeptidase family protein 0.0068 0.0101 0.0157
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0423 0.2375 0.3676
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0077 0.0162 0.0233
Loa Loa (eye worm) thyroid receptor interactor 0.0121 0.0442 0.0684
Schistosoma mansoni suppressor of cytokine signaling 0.0056 0.0027 0.0052
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0111 0.0379 0.0655
Schistosoma mansoni protein kinase 0.007 0.0115 0.0223
Loa Loa (eye worm) hypothetical protein 0.014 0.056 0.0866
Loa Loa (eye worm) hypothetical protein 0.0068 0.0101 0.0157
Echinococcus granulosus Protein kinase C brain isozyme 0.0265 0.1361 0.1957
Echinococcus multilocularis SH2 motif 0.0056 0.0027 0.0046
Echinococcus multilocularis tyrosine protein kinase Srms 0.0197 0.0926 0.1602
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0056 0.0027 0.0046
Schistosoma mansoni protein kinase 0.0488 0.2787 0.5418
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0423 0.2375 0.3676
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0125 0.0467 0.0451
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0233 0.0454
Schistosoma mansoni protein kinase 0.0095 0.0272 0.0528
Brugia malayi cytokine inducible SH2-containing protein 5 0.0056 0.0027 0.0041
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0168 0.074 0.1146
Onchocerca volvulus 0.0098 0.0293 0.052
Brugia malayi Protein kinase domain containing protein 0.0171 0.0763 0.1181
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0149 0.0623 0.1077
Loa Loa (eye worm) SH2 domain-containing protein 0.0056 0.0027 0.0041
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0076 0.0152 0.0343
Echinococcus multilocularis 0.017 0.0757 0.1309
Trichomonas vaginalis AGC family protein kinase 0.032 0.1712 0.7187
Entamoeba histolytica protein kinase domain containing protein 0.0143 0.058 0.235
Echinococcus granulosus suppressor of cytokine signaling 7 0.0056 0.0027 0.0038
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.008 0.0182 0.0281
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0761 0.1479
Giardia lamblia Kinase, CAMK CAMKL 0.0098 0.0296 0.1282
Echinococcus multilocularis myotubularin protein 13 0.0056 0.0024 0.0042
Toxoplasma gondii DNA topoisomerase 2, putative 0.0423 0.2375 0.2362
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0441 0.2484 0.3572
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0509 0.2087
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Onchocerca volvulus 0.0099 0.0299 0.0532
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0068 0.0101 0.0099
Plasmodium falciparum casein kinase 1 0.012 0.0435 0.042
Echinococcus multilocularis hypothetical protein 0.0081 0.0183 0.0316
Brugia malayi prolyl oligopeptidase family protein 0.0288 0.1509 0.2336
Toxoplasma gondii aurora kinase 0.0098 0.0295 0.0279
Plasmodium falciparum serine/threonine protein kinase KIN 0.0098 0.0296 0.028
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Entamoeba histolytica protein kinase , putative 0.0098 0.0295 0.1161
Loa Loa (eye worm) hypothetical protein 0.0217 0.1057 0.1636
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0288 0.1509 0.1495
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0066 0.0089 0.0137
Schistosoma mansoni ephrin receptor 0.0114 0.0394 0.0766
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0068 0.0101 0.0197
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0266 0.1371 0.2122
Echinococcus granulosus NDR protein kinase 0.0171 0.0763 0.1097
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.029 0.045
Echinococcus granulosus titin 0.0066 0.0089 0.0127
Plasmodium vivax tyrosine kinase-like protein, putative 0.0089 0.0236 0.0219
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0089 0.0239 0.0413
Leishmania major protein kinase, putative 0.0093 0.0262 0.0621
Trypanosoma cruzi hypothetical protein, conserved 0.0068 0.0101 0.0215
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0093 0.0262 0.0621
Echinococcus multilocularis growth factor receptor bound protein 2 0.0092 0.0253 0.0437
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0183 0.0837 0.2078
Brugia malayi Tyrosine-protein kinase abl-1 0.0145 0.0593 0.0919
Loa Loa (eye worm) hypothetical protein 0.0056 0.0027 0.0041
Onchocerca volvulus Prolyl endopeptidase homolog 0.0068 0.0101 0.0146
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0266 0.1371 0.237
Brugia malayi Sex muscle abnormal protein 5 0.0092 0.0253 0.0391
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.0162 0.0315
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0423 0.2375 0.4106
Giardia lamblia Kinase, AGC AKT 0.013 0.0496 0.2199
Echinococcus multilocularis epidermal growth factor receptor 0.0512 0.2938 0.508
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0093 0.0262 0.0621
Entamoeba histolytica protein kinase, putative 0.0113 0.0388 0.1549
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0089 0.0239 0.037
Echinococcus multilocularis mitogen activated protein kinase 0.0092 0.0255 0.0441
Loa Loa (eye worm) hypothetical protein 0.008 0.0182 0.0281
Onchocerca volvulus 0.0072 0.013 0.0202
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0265 0.1365 0.2359
Brugia malayi hypothetical protein 0.022 0.1075 0.1664
Brugia malayi MAP kinase sur-1 0.0092 0.0255 0.0395
Plasmodium vivax unspecified product 0.011 0.0374 0.0358
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0068 0.0101 0.0215
Schistosoma mansoni tyrosine kinase 0.0251 0.1269 0.2467
Echinococcus multilocularis mitogen activated protein kinase 14 0.0177 0.08 0.1384
Loa Loa (eye worm) hypothetical protein 0.0056 0.0027 0.0041
Brugia malayi putative serine/threonine kinase SADA gamma 0.0098 0.0296 0.0459
Loa Loa (eye worm) protein kinase domain-containing protein 0.0238 0.1192 0.1844
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0396 0.2199 0.3162
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0045 0.0087
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0232 0.1152 0.1657
Echinococcus multilocularis serine:threonine protein kinase 0.008 0.0182 0.0314
Echinococcus granulosus defective proboscis extension response 0.0094 0.027 0.0389
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0091 0.0251 0.0593
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0138 0.0551 0.1353
Toxoplasma gondii casein kinase I 0.012 0.0435 0.042
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Echinococcus multilocularis myosin iiia 0.0093 0.0262 0.0453
Brugia malayi STE20-like kinase MST 0.0288 0.1507 0.2332
Loa Loa (eye worm) hypothetical protein 0.0676 0.3988 0.6173
Loa Loa (eye worm) hypothetical protein 0.0204 0.0973 0.1506
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0251 0.0487
Echinococcus multilocularis dual specificity 0.0154 0.0655 0.1132
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0077 0.0162 0.0233
Giardia lamblia Kinase, CMGC SRPK 0.0091 0.0251 0.1073
Echinococcus granulosus protein kinase shaggy 0.0143 0.058 0.0834
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0098 0.0296 0.028
Brugia malayi hypothetical protein 0.0056 0.0027 0.0041
Trichomonas vaginalis STE family protein kinase 0.0095 0.0272 0.1082
Schistosoma mansoni protein kinase 0.0268 0.1383 0.2687
Echinococcus multilocularis nervana 2 0.014 0.0561 0.0971
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0087 0.0221 0.0342
Schistosoma mansoni serine/threonine protein kinase 0.0266 0.1371 0.2665
Loa Loa (eye worm) hypothetical protein 0.0328 0.1766 0.2734
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0556 0.3224 0.4636
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.092 0.3829
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0171 0.0761 0.1884
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0377 0.2075 0.3213
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.017 0.0757 0.1172
Loa Loa (eye worm) hypothetical protein 0.0162 0.0705 0.1092
Loa Loa (eye worm) TK/INSR protein kinase 0.0443 0.2501 0.3871
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0266 0.1371 0.1971
Giardia lamblia DNA topoisomerase II 0.0396 0.2199 1
Trichomonas vaginalis AGC family protein kinase 0.0171 0.0763 0.3164
Echinococcus multilocularis NCK adaptor protein 0.0094 0.0267 0.0462
Onchocerca volvulus Serine\/threonine kinase homolog 0.0196 0.092 0.1744
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.014 0.0561 0.0807
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0092 0.0255 0.0604
Loa Loa (eye worm) hypothetical protein 0.014 0.056 0.0866
Loa Loa (eye worm) SRC-1 0.0232 0.1152 0.1784
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0171 0.0763 0.1319
Loa Loa (eye worm) hypothetical protein 0.0097 0.0288 0.0446
Echinococcus granulosus fibroblast growth factor receptor 4 0.0265 0.1365 0.1962
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0111 0.0379 0.0918
Schistosoma mansoni tyrosine kinase 0.0133 0.0516 0.1004
Entamoeba histolytica protein kinase, putative 0.0098 0.0295 0.1161
Plasmodium vivax DNA topoisomerase II, putative 0.0423 0.2375 0.2362
Loa Loa (eye worm) ICD-1 protein 0.0076 0.0152 0.0236
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0089 0.0172
Brugia malayi Pleckstrin Homology Domain 0.0056 0.0024 0.0038
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0171 0.0761 0.1884
Echinococcus multilocularis cyclin dependent kinase 5 0.0132 0.0509 0.088
Echinococcus multilocularis calcium activated potassium channel 0.0115 0.0404 0.0698
Schistosoma mansoni protein-s-isoprenylcysteine o-methyltransferase 0.012 0.0435 0.0845
Brugia malayi Protein kinase domain 0.0095 0.0272 0.0421
Loa Loa (eye worm) hypothetical protein 0.0101 0.0314 0.0486
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0098 0.0295 0.1161
Echinococcus granulosus casein kinase I delta 0.012 0.0435 0.0626
Schistosoma mansoni protein kinase 0.0076 0.0152 0.0295
Trichomonas vaginalis CMGC family protein kinase 0.0171 0.0761 0.3155
Echinococcus granulosus dual specificity protein kinase clk2 0.0171 0.0761 0.1094
Schistosoma mansoni serine/threonine protein kinase 0.0207 0.0993 0.193
Entamoeba histolytica hypothetical protein 0.0115 0.04 0.1598
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0171 0.0763 0.1181
Giardia lamblia Kinase, AGC PKA 0.0174 0.0782 0.3509
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0111 0.0379 0.0655
Entamoeba histolytica hypothetical protein 0.043 0.2415 1
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0857 0.5145 1
Echinococcus multilocularis activin receptor type 0.0076 0.0152 0.0263
Loa Loa (eye worm) hypothetical protein 0.0054 0.0013 0.0021
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0288 0.1509 0.3779
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0081 0.0184 0.0285
Brugia malayi Protein kinase domain containing protein 0.0171 0.0761 0.1178
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0077 0.0162 0.028
Schistosoma mansoni growth factor receptor-bound protein 0.0092 0.0253 0.0491
Echinococcus multilocularis transcription factor btf3 0.0076 0.0152 0.0263
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0092 0.0255 0.0604
Trichomonas vaginalis STE family protein kinase 0.0093 0.0262 0.104
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0089 0.0239 0.0344
Echinococcus granulosus SH2 motif 0.0056 0.0027 0.0038
Brugia malayi Immunoglobulin I-set domain containing protein 0.0101 0.0314 0.0486
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0361 0.1973 0.4954
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0379 0.1537
Giardia lamblia DNA topoisomerase III 0.0063 0.0069 0.024
Plasmodium falciparum cGMP-dependent protein kinase 0.0149 0.0623 0.0607
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.1101 0.2141
Onchocerca volvulus Tyrosine kinase homolog 0.0615 0.36 0.6982
Plasmodium falciparum protein kinase 5 0.0132 0.0509 0.0493
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0136 0.0534 0.1309
Schistosoma mansoni tyrosine kinase 0.0313 0.1671 0.3248
Entamoeba histolytica p21-activated kinase 0.0103 0.0326 0.1292
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0232 0.1152 0.1992
Loa Loa (eye worm) hypothetical protein 0.0157 0.0671 0.1038
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0103 0.0329 0.0639
Plasmodium vivax glycogen synthase kinase 3, putative 0.0143 0.058 0.0565
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0655 0.2706
Loa Loa (eye worm) hypothetical protein 0.0056 0.0027 0.0041
Echinococcus granulosus SH2 motif 0.0056 0.0027 0.0038
Trypanosoma cruzi polo-like protein kinase, putative 0.0196 0.092 0.2286
Leishmania major oligopeptidase b 0.0068 0.0101 0.0215
Trypanosoma cruzi hypothetical protein, conserved 0.0068 0.0101 0.0215
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0196 0.092 0.2286
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0296 0.0576
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0232 0.1152 0.1992
Onchocerca volvulus 0.033 0.178 0.3425
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0091 0.0251 0.0593
Brugia malayi SH2 domain containing protein 0.0056 0.0027 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0655 0.1273
Mycobacterium ulcerans DNA gyrase subunit B 0.0796 0.4756 0.4755
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0094 0.027 0.0468
Loa Loa (eye worm) hypothetical protein 0.0056 0.0027 0.0041
Schistosoma mansoni protein kinase 0.0258 0.1316 0.2559
Echinococcus granulosus epidermal growth factor receptor 0.0355 0.1935 0.2782
Loa Loa (eye worm) prolyl oligopeptidase 0.0857 0.5145 0.7964
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.011 0.0374 0.0578
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0655 0.2706
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0125 0.0467 0.0672
Brugia malayi serine/threonine kinase 12 0.0098 0.0295 0.0457
Loa Loa (eye worm) AGC/NDR protein kinase 0.0171 0.0763 0.1181
Echinococcus multilocularis N chimaerin 0.0103 0.0329 0.0569
Echinococcus multilocularis twitchin 0.0059 0.0045 0.0078
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0443 0.25 0.3595
Plasmodium falciparum calcium-dependent protein kinase 5 0.0111 0.0379 0.0363
Loa Loa (eye worm) hypothetical protein 0.0101 0.0313 0.0484
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0676 0.3988 0.6173
Trichomonas vaginalis DNA topoisomerase II, putative 0.0423 0.2375 1
Entamoeba histolytica protein kinase, putative 0.0077 0.0162 0.0607
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0125 0.0467 0.0723
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0149 0.0623 0.1077
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0094 0.027 0.0526
Brugia malayi Variant SH3 domain containing protein 0.0066 0.009 0.014
Plasmodium falciparum NIMA related kinase 1 0.0151 0.0634 0.0619
Echinococcus granulosus tyrosine protein kinase Fyn 0.0232 0.1152 0.1657
Loa Loa (eye worm) TK/EGFR protein kinase 0.0512 0.2938 0.4548
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0098 0.0295 0.0279
Trichomonas vaginalis AGC family protein kinase 0.0125 0.0467 0.191
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0125 0.0467 0.1141
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0111 0.0379 0.0363
Schistosoma mansoni adapter molecule crk 0.0092 0.0253 0.0491
Brugia malayi SH2 domain containing protein 0.0056 0.0027 0.0041
Schistosoma mansoni hypothetical protein 0.0313 0.1668 0.3243
Entamoeba histolytica protein kinase, putative 0.0095 0.0272 0.1064
Toxoplasma gondii histone kinase SNF1, putative 0.0098 0.0296 0.028
Echinococcus granulosus aurora kinase A 0.0098 0.0295 0.0424
Echinococcus granulosus N chimaerin 0.0103 0.0329 0.0473
Loa Loa (eye worm) hypothetical protein 0.0068 0.0101 0.0157
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0234 0.1167 0.1677
Entamoeba histolytica protein kinase, putative 0.0091 0.0248 0.0963
Loa Loa (eye worm) SH2 domain-containing protein 0.0056 0.0027 0.0041
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0171 0.0761 0.1178
Echinococcus granulosus tyrosine kinase 0.0097 0.029 0.0418
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0705 0.4179 0.6468
Echinococcus granulosus calcium activated potassium channel 0.0115 0.0404 0.0581
Giardia lamblia Kinase, NEK 0.0151 0.0634 0.2831
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0091 0.0251 0.0388
Loa Loa (eye worm) TK/FER protein kinase 0.0441 0.2484 0.3845
Echinococcus granulosus mitogen activated protein kinase 14 0.0177 0.08 0.1151
Brugia malayi Protein kinase domain containing protein 0.0215 0.1044 0.1616
Schistosoma mansoni nephrin 0.0126 0.0471 0.0915
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0132 0.0509 0.1247
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0154 0.0655 0.1616
Toxoplasma gondii AGC kinase 0.0125 0.0467 0.0451
Schistosoma mansoni protein kinase 0.017 0.0757 0.1472
Loa Loa (eye worm) hypothetical protein 0.0133 0.0518 0.0802
Loa Loa (eye worm) AGC/PKA protein kinase 0.0125 0.0467 0.0723
Brugia malayi Protein kinase domain containing protein 0.0676 0.3988 0.6173
Entamoeba histolytica hypothetical protein 0.0115 0.04 0.1598
Schistosoma mansoni protein kinase 0.0076 0.0152 0.0295
Echinococcus granulosus acylamino acid releasing enzyme 0.0068 0.0101 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0101 0.036
Brugia malayi map kinase activated protein kinase protein 2 0.0443 0.25 0.387
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0143 0.058 0.0834
Brugia malayi C1-like domain containing protein 0.0243 0.1223 0.1893
Loa Loa (eye worm) CAMK protein kinase 0.0066 0.0089 0.0137
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0234 0.1162 0.167
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0183 0.0836 0.1202
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0092 0.0255 0.0604
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0482 0.1973
Schistosoma mansoni tyrosine kinase 0.0313 0.1671 0.3248
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.114 0.6955 1
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0171 0.0763 0.1319
Leishmania major casein kinase, putative 0.012 0.0435 0.1061
Brugia malayi casein kinase 1, delta 0.012 0.0435 0.0674
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0098 0.0296 0.0708
Schistosoma mansoni signal transduction protein lnk-related 0.0056 0.0027 0.0052
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0196 0.092 0.1423
Loa Loa (eye worm) hypothetical protein 0.0098 0.0293 0.0453
Loa Loa (eye worm) AUR protein kinase 0.0098 0.0295 0.0457
Echinococcus granulosus cGMP dependent protein kinase 1 0.0149 0.0623 0.0896
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0098 0.0293 0.0699
Plasmodium vivax protein kinase, putative 0.0058 0.004 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.1167 0.2267
Echinococcus granulosus nervana 2 0.014 0.0561 0.0807
Echinococcus multilocularis SH2 motif 0.0056 0.0027 0.0046
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0672 0.3966 1
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0111 0.0379 0.0363
Echinococcus multilocularis SH2 domain containing protein 7 0.0056 0.0027 0.0046
Brugia malayi SH2 domain containing protein 0.0056 0.0027 0.0041
Brugia malayi hypothetical protein 0.0133 0.0518 0.0802
Trypanosoma cruzi DNA topoisomerase III, putative 0.0063 0.0069 0.0133
Echinococcus granulosus serine:threonine protein kinase N2 0.0318 0.17 0.2445
Schistosoma mansoni tensin-related 0.0056 0.0027 0.0052
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0068 0.0101 0.0197
Brugia malayi Protein kinase domain containing protein 0.0216 0.1051 0.1626
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0361 0.1973 0.4954
Loa Loa (eye worm) hypothetical protein 0.0094 0.027 0.0419
Echinococcus granulosus serine:threonine protein kinase N2 0.0147 0.0605 0.0869
Loa Loa (eye worm) TK protein kinase 0.0141 0.0567 0.0878
Onchocerca volvulus 0.0209 0.1002 0.1906
Schistosoma mansoni tensin-related 0.0056 0.0027 0.0052
Schistosoma mansoni hypothetical protein 0.0081 0.0183 0.0355
Entamoeba histolytica protein kinase 2, putative 0.0174 0.0782 0.3192
Loa Loa (eye worm) AUR protein kinase 0.0098 0.0295 0.0457
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0288 0.1509 0.3779
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0171 0.0761 0.1884
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0091 0.0246 0.0354
Entamoeba histolytica protein kinase domain containing protein 0.0098 0.0295 0.1161
Echinococcus multilocularis casein kinase I gamma 0.0238 0.1192 0.206
Echinococcus multilocularis dual specificity 0.0154 0.0655 0.1132
Echinococcus multilocularis dual specificity 0.0136 0.0534 0.0923
Onchocerca volvulus 0.0097 0.029 0.0515
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0076 0.0152 0.0218
Onchocerca volvulus 0.0097 0.029 0.0515
Entamoeba histolytica protein kinase, putative 0.0311 0.1657 0.6839
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0232 0.1152 0.1992
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0045 0.0087
Plasmodium falciparum peptidase, putative 0.0068 0.0101 0.0085
Brugia malayi Protein kinase domain containing protein 0.0676 0.3988 0.6173
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0249 0.1257 0.1807
Trichomonas vaginalis STE family protein kinase 0.0095 0.0272 0.1082
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.0299 0.1197
Loa Loa (eye worm) hypothetical protein 0.0095 0.0273 0.0422
Leishmania major prenyl protein specific carboxyl methyltransferase, putative 0.012 0.0435 0.1059
Brugia malayi protein unc-22 0.0066 0.0089 0.0137
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0068 0.0101 0.0072
Echinococcus granulosus netrin receptor unc 5 0.0055 0.0019 0.0028
Trichomonas vaginalis AGC family protein kinase 0.032 0.1712 0.7187
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.058 0.239
Loa Loa (eye worm) protein-S isoprenylcysteine O-methyltransferase 0.012 0.0435 0.0673
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.0496 0.0768
Echinococcus granulosus tyrosine protein kinase Src42A 0.0232 0.1152 0.1657
Echinococcus granulosus SHC transforming protein 3 0.0056 0.0027 0.0038
Giardia lamblia Kinase, CMGC CLK 0.0171 0.0761 0.341
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0232 0.1152 0.1992
Schistosoma mansoni vav2 0.0112 0.0384 0.0746
Brugia malayi Protein kinase domain containing protein 0.032 0.1712 0.2649
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0056 0.0027 0.0041
Trypanosoma cruzi Protein kinase B 0.0183 0.0837 0.2078
Echinococcus multilocularis cyclin dependent kinase 0.0132 0.0509 0.088
Plasmodium falciparum DNA gyrase subunit A 0.1616 1 1
Schistosoma mansoni protein kinase 0.0095 0.0272 0.0528
Brugia malayi Protein kinase domain containing protein 0.0097 0.029 0.045
Entamoeba histolytica prolyl oligopeptidase family protein 0.0068 0.0101 0.0354
Brugia malayi Serine/threonine-protein kinase SULU 0.0249 0.1257 0.1945
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.012 0.0435 0.1773
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Loa Loa (eye worm) AUR protein kinase 0.0098 0.0295 0.0457
Echinococcus multilocularis SH2 motif 0.0056 0.0027 0.0046
Trypanosoma brucei casein kinase I, isoform 2 0.012 0.0435 0.1061
Echinococcus multilocularis snurportin 1 0.0334 0.1805 0.3121
Echinococcus multilocularis casein kinase I alpha 0.012 0.0435 0.0753
Echinococcus granulosus tyrosine protein kinase shark 0.0339 0.1835 0.2638
Brugia malayi Doublecortin family protein 0.0168 0.074 0.1146
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0258 0.1316 0.2276
Echinococcus multilocularis casein kinase I alpha 0.012 0.0435 0.0753
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0226 0.1115 0.1603
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0255 0.0496
Schistosoma mansoni rap gtpase-activating protein 0.0098 0.0293 0.0569
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0255 0.1012
Loa Loa (eye worm) TK protein kinase 0.0384 0.2125 0.3289
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0857 0.5145 0.7397
Trypanosoma brucei DNA topoisomerase ii 0.0672 0.3966 1
Echinococcus granulosus cGMP dependent protein kinase 1 0.0149 0.0623 0.0896
Echinococcus multilocularis X box binding protein 1 0.0313 0.1668 0.2884
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0402 0.2239 0.4323
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0249 0.1257 0.1945
Trypanosoma brucei protein kinase, putative 0.0092 0.0255 0.0604
Schistosoma mansoni transcription factor LCR-F1 0.0115 0.04 0.0777
Brugia malayi STAT protein, DNA binding domain containing protein 0.0056 0.0027 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0239 0.0943
Schistosoma mansoni ste20-related kinase 0.0229 0.1133 0.2202
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0098 0.0295 0.1161
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0396 0.2199 0.3404
Entamoeba histolytica casein kinase, putative 0.012 0.0435 0.1747
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0556 0.3224 0.5575
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0443 0.25 0.387
Brugia malayi Protein kinase domain containing protein 0.0443 0.2501 0.3871
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0076 0.0152 0.0136
Trypanosoma cruzi cdc2-related kinase 3 0.0132 0.0509 0.1247
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0171 0.0763 0.1097
Entamoeba histolytica DNA topoisomerase III, putative 0.0063 0.0069 0.0219
Loa Loa (eye worm) hypothetical protein 0.0101 0.0313 0.0484
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.029 0.045
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0208 0.0998 0.1544
Schistosoma mansoni serine/threonine protein kinase 0.0443 0.25 0.4859
Loa Loa (eye worm) hypothetical protein 0.0056 0.0027 0.0041
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0182 0.0834 0.1291
Echinococcus multilocularis tyrosine protein kinase Abl 0.0222 0.109 0.1884
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0092 0.0255 0.0604
Schistosoma mansoni protein kinase 0.011 0.0374 0.0726
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0177 0.08 0.1985
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0226 0.1115 0.1928
Entamoeba histolytica PH domain containing protein kinase, putative 0.0134 0.0522 0.2106
Schistosoma mansoni tyrosine kinase 0.0086 0.022 0.0428
Brugia malayi Variant SH3 domain containing protein 0.0092 0.0253 0.0391
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0174 0.0782 0.0767
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0655 0.2706
Loa Loa (eye worm) hypothetical protein 0.0072 0.013 0.0201
Schistosoma mansoni protein kinase 0.012 0.0435 0.0846
Echinococcus granulosus tyrosine kinase 0.0197 0.0926 0.1332
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0226 0.1115 0.1726
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0232 0.1152 0.1992
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0056 0.0027 0.0046
Trypanosoma cruzi casein kinase, putative 0.012 0.0435 0.1061
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0095 0.0272 0.0391
Brugia malayi hypothetical protein 0.0101 0.0314 0.0486
Giardia lamblia DNA topoisomerase III 0.0063 0.0069 0.024
Loa Loa (eye worm) hypothetical protein 0.0115 0.0403 0.0623
Loa Loa (eye worm) hypothetical protein 0.0098 0.0296 0.0459
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0092 0.0255 0.0604
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Echinococcus granulosus myotubularin protein 13 0.0056 0.0024 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Echinococcus multilocularis aurora kinase A 0.0098 0.0295 0.051
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.0299 0.1197
Echinococcus multilocularis serine:threonine protein kinase N2 0.0318 0.17 0.294
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0068 0.0101 0.036
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0127 0.0482 0.0833
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0059 0.0045 0.007
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0136 0.0534 0.1309
Onchocerca volvulus 0.0097 0.029 0.0515
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0404 0.0785
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0154 0.0655 0.1616
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0089 0.0239 0.037
Echinococcus granulosus tyrosine protein kinase HCK 0.0141 0.0567 0.0815
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.058 0.239
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0098 0.0293 0.0699
Schistosoma mansoni hypothetical protein 0.0056 0.0027 0.0052
Echinococcus multilocularis mitogen activated protein kinase 11 0.0177 0.08 0.1384
Brugia malayi Protein kinase domain containing protein 0.0183 0.0836 0.1294
Loa Loa (eye worm) STAT protein 0.0056 0.0027 0.0041
Giardia lamblia Kinase, CAMK CAMKL 0.0098 0.0296 0.1282
Schistosoma mansoni growth factor receptor-bound protein 0.0094 0.0267 0.0519
Loa Loa (eye worm) hypothetical protein 0.0056 0.0027 0.0041
Echinococcus granulosus protein kinase 0.017 0.0757 0.1089
Brugia malayi GRF zinc finger family protein 0.0063 0.0069 0.0107
Entamoeba histolytica hypothetical protein, conserved 0.0068 0.0101 0.0354
Brugia malayi Fibronectin type III domain containing protein 0.0101 0.0314 0.0486
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0098 0.0296 0.0708
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0183 0.0836 0.1294
Echinococcus multilocularis rho associated protein kinase 0.0365 0.2001 0.3459
Echinococcus granulosus cyclin dependent kinase 0.0132 0.0509 0.0732
Echinococcus granulosus tyrosine protein kinase Srms 0.0558 0.3238 0.4656
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0232 0.1152 0.1657
Echinococcus multilocularis tyrosine protein kinase shark 0.0339 0.1835 0.3173
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0154 0.0655 0.1013
Entamoeba histolytica DNA topoisomerase II, putative 0.0423 0.2375 0.9832
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0334 0.1805 0.2794
Echinococcus multilocularis dual specificity 0.0154 0.0655 0.1132
Trypanosoma brucei transcription factor BTF3, putative 0.0076 0.0152 0.0344
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0111 0.0379 0.0363
Trypanosoma brucei rac serine-threonine kinase, putative 0.032 0.1712 0.4292
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0098 0.0293 0.0569
Giardia lamblia Kinase, NEK 0.0151 0.0634 0.2831
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0059 0.0045 0.007
Plasmodium vivax DNA topoisomerase 3, putative 0.0063 0.0069 0.0053
Entamoeba histolytica hypothetical protein 0.0115 0.04 0.1598
Echinococcus granulosus tensin 0.0056 0.0027 0.0038
Echinococcus granulosus tyrosine protein kinase Lyn 0.0267 0.1373 0.1975
Entamoeba histolytica protein kinase domain containing protein 0.0226 0.1115 0.4579
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0093 0.0262 0.1023
Onchocerca volvulus 0.0161 0.07 0.1316
Echinococcus multilocularis roundabout 2 0.0146 0.0603 0.1043
Plasmodium falciparum protein serine/threonine kinase-1 0.0171 0.0761 0.0745
Echinococcus multilocularis serine:threonine protein kinase N2 0.0171 0.0763 0.1319
Plasmodium falciparum serine/threonine protein kinase, putative 0.0098 0.0295 0.0279
Echinococcus granulosus mitogen activated protein kinase 3 0.0092 0.0255 0.0367
Entamoeba histolytica protein kinase, putative 0.0136 0.0534 0.2156
Echinococcus granulosus protein kinase c iota type 0.0312 0.1665 0.2393
Echinococcus granulosus signal transduction protein lnk realted 0.0056 0.0027 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.17 0.3305
Echinococcus multilocularis protein kinase c iota type 0.0312 0.1665 0.2878
Echinococcus granulosus mitogen activated protein kinase 0.0092 0.0255 0.0367
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0132 0.0509 0.0788
Echinococcus multilocularis cyclin dependent kinase 1 0.0132 0.0509 0.088
Echinococcus granulosus ephrin type A receptor 4 A 0.0114 0.0394 0.0566
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0143 0.058 0.0565
Echinococcus multilocularis tensin 0.0056 0.0027 0.0046
Echinococcus granulosus protein S isoprenylcysteine O methyltransferase 0.012 0.0435 0.0625
Echinococcus multilocularis serine:threonine protein kinase N2 0.0147 0.0605 0.1045
Toxoplasma gondii isoprenylcysteine carboxyl methyltransferase (icmt) family protein 0.012 0.0435 0.0419
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0355 0.1935 0.2782
Loa Loa (eye worm) AGC/PKN protein kinase 0.0318 0.17 0.2632
Loa Loa (eye worm) AGC/PKG protein kinase 0.0149 0.0623 0.0964
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0374 0.1514
Echinococcus granulosus Dipeptidyl peptidase 9 0.0288 0.1509 0.2169
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0374 0.1514
Schistosoma mansoni serine/threonine protein kinase 0.0136 0.0534 0.1037
Trypanosoma brucei protein kinase, putative 0.0143 0.058 0.1427
Chlamydia trachomatis DNA gyrase subunit B 0.0547 0.3165 0.3118
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0402 0.2239 0.4323
Trichomonas vaginalis CAMK family protein kinase 0.0196 0.092 0.3829
Trypanosoma brucei SNF1-related protein kinases, putative 0.0098 0.0296 0.0708
Entamoeba histolytica protein kinase, putative 0.0091 0.0251 0.0976
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0761 0.1479
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0396 0.2199 0.4244
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0207 0.0993 0.1428
Onchocerca volvulus 0.0066 0.0089 0.0121
Leishmania major DNA topoisomerase 1A 0.0063 0.0069 0.0133
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0063 0.0069 0.0107
Brugia malayi RNA, U transporter 1 0.0089 0.0237 0.0366
Echinococcus multilocularis CDC7 cell division cycle 7 0.0099 0.0299 0.0517
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0374 0.1514
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0161 0.0697 0.1002
Plasmodium falciparum calcium-dependent protein kinase 3 0.0111 0.0379 0.0363
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0098 0.0293 0.0569
Schistosoma mansoni protein kinase 0.0098 0.0295 0.0573
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.1616 1 1
Brugia malayi hypothetical protein 0.0098 0.0293 0.0453
Schistosoma mansoni tyrosine kinase 0.0283 0.1475 0.2866
Trichomonas vaginalis AGC family protein kinase 0.032 0.1712 0.7187
Entamoeba histolytica protein kinase, putative 0.0079 0.017 0.0638
Plasmodium falciparum basic transcription factor 3b, putative 0.0076 0.0152 0.0136
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0125 0.0467 0.1141
Schistosoma mansoni protein kinase C mu 0.0243 0.1223 0.2378
Plasmodium vivax casein kinase 1, putative 0.012 0.0435 0.042
Echinococcus granulosus dual specificity 0.0154 0.0655 0.0941
Echinococcus multilocularis expressed protein 0.0091 0.0251 0.0433
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0125 0.0467 0.0672
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0098 0.0296 0.0459
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0098 0.0296 0.0708
Entamoeba histolytica casein kinase 1, putative 0.012 0.0435 0.1747
Chlamydia trachomatis DNA gyrase subunit A 0.018 0.0821 0.0757
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0098 0.0295 0.0424
Brugia malayi Immunoglobulin I-set domain containing protein 0.029 0.1521 0.2355
Echinococcus granulosus casein kinase I gamma 0.0238 0.1192 0.1713
Echinococcus granulosus hypothetical protein 0.0136 0.054 0.0776
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0623 0.1211
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0095 0.0272 0.0391
Giardia lamblia Kinase, CMGC CK2 0.011 0.0374 0.1637
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0125 0.0467 0.0808
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0132 0.0509 0.0788
Brugia malayi probable protein kinase 0.0268 0.1383 0.214
Echinococcus multilocularis mitogen activated protein kinase 3 0.0092 0.0255 0.0441
Brugia malayi MH2 domain containing protein 0.013 0.0496 0.0768
Echinococcus multilocularis c src tyrosine kinase 0.0133 0.0516 0.0893
Plasmodium falciparum DNA gyrase subunit B 0.0796 0.4756 0.4747
Loa Loa (eye worm) hypothetical protein 0.0135 0.0527 0.0816
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0056 0.0027 0.0038
Entamoeba histolytica PH domain containing protein kinase, putative 0.0183 0.0837 0.342
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0154 0.0655 0.0639
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0374 0.1514
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0161 0.0697 0.1205
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0623 0.1211
Brugia malayi Protein kinase domain containing protein 0.0396 0.2199 0.3404
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0174 0.0782 0.0767
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0132 0.0509 0.1247
Giardia lamblia Alanyl dipeptidyl peptidase 0.0068 0.0101 0.0389
Brugia malayi Casein kinase II, alpha chain 0.011 0.0374 0.0578
Echinococcus granulosus cyclin dependent kinase 5 0.0132 0.0509 0.0732
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0196 0.092 0.159
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0509 0.2087
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0296 0.1186
Trichomonas vaginalis CK1 family protein kinase 0.012 0.0435 0.1776
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0143 0.058 0.1427
Echinococcus granulosus cGMP dependent protein kinase 0.0149 0.0623 0.0896
Echinococcus granulosus tyrosine protein kinase Blk 0.0197 0.0926 0.1332

Activities

Activity type Activity value Assay description Source Reference
Kd (binding) = 7.49 Binding affinity at rat 5-hydroxytryptamine receptor. ChEMBL. 7143352
Ki (binding) = 210 nM Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]-KET as a radioligand ChEMBL. 3543362
Ki (binding) = 13200 nM Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand. ChEMBL. 3543362

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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