Detailed information for compound 1598326

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 449.34 | Formula: C19H14F3N5O5
  • H donors: 1 H acceptors: 5 LogP: 3.01 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(cc1)c1ccc(nc1)C(F)(F)F)O[C@@H]1COc2n(C1)cc(n2)[N+](=O)[O-]
  • InChi: 1S/C19H14F3N5O5/c20-19(21,22)15-6-3-12(7-23-15)11-1-4-13(5-2-11)24-18(28)32-14-8-26-9-16(27(29)30)25-17(26)31-10-14/h1-7,9,14H,8,10H2,(H,24,28)/t14-/m0/s1
  • InChiKey: RNOPUWJORKDLQS-AWEZNQCLSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Onchocerca volvulus 0.001 0.0005 0.0018
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0018 0.0052 0.0299
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0044 0.0044
Echinococcus granulosus low density lipoprotein receptor ldl 0.0028 0.011 0.0133
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.001 0.0005 0.0006
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0074 0.1084
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0074 0.1154
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0045 0.021 0.1206
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0072 0.0087
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.0129 0.0369
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0065 0.0323 0.0389
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0019 0.0058 0.0334
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0066 0.008
Echinococcus multilocularis tyrosine protein kinase Fyn 0.001 0.0005 0.0006
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0019 0.0058 0.0334
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0249 0.0249
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0199 0.024
Echinococcus granulosus caspase 2 0.0098 0.0517 0.0623
Onchocerca volvulus 0.0071 0.036 0.1296
Trypanosoma cruzi Macro domain containing protein, putative 0.0014 0.0027 0.0422
Echinococcus multilocularis dna polymerase eta 0.0035 0.0154 0.0185
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0012 0.0015 0.0018
Schistosoma mansoni steroid hormone receptor ad4bp 0.0043 0.0199 0.024
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.001 0.0005 0.0006
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0005 0.0005
Onchocerca volvulus Protein ultraspiracle homolog 0.0043 0.0199 0.0717
Schistosoma mansoni thyroid hormone receptor 0.0182 0.1002 0.1207
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0019 0.0058 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Onchocerca volvulus Bile acid receptor homolog 0.0043 0.0199 0.0717
Brugia malayi CXXC zinc finger family protein 0.0028 0.0112 0.0112
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0641 0.184
Echinococcus granulosus tyrosine protein kinase Src64B 0.001 0.0005 0.0006
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.007 0.0084
Echinococcus multilocularis expressed protein 0.041 0.233 0.2807
Brugia malayi nuclear receptor NHR-67 0.002 0.0066 0.0066
Schistosoma mansoni hypothetical protein 0.0028 0.011 0.0133
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.0683 0.0822
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0035 0.0149 0.018
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.0641 0.0772
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0081 0.0419 0.0505
Loa Loa (eye worm) hypothetical protein 0.0045 0.021 0.021
Echinococcus granulosus bloom syndrome protein 0.0022 0.0074 0.0089
Echinococcus multilocularis muscleblind protein 0.0164 0.0901 0.1085
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0061 0.03 0.0361
Brugia malayi SH2 domain containing protein 0.001 0.0005 0.0005
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0332 0.04
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0057 0.0069
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Plasmodium vivax glutathione reductase, putative 0.0052 0.0249 0.4818
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0199
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Echinococcus granulosus basement membrane specific heparan sulfate 0.0028 0.011 0.0133
Schistosoma mansoni netrin receptor unc5 0.0028 0.011 0.0133
Brugia malayi conserved hypotetical protein 0.002 0.0066 0.0066
Leishmania major trypanothione reductase 0.0052 0.0249 0.3652
Echinococcus multilocularis musashi 0.003 0.012 0.0144
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0129 0.0129
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.0129 0.0369
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0012 0.0015 0.0018
Trypanosoma brucei hypothetical protein, conserved 0.0011 0.0011 0.0178
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0019 0.0058 0.0334
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0102 0.0294
Trypanosoma brucei prostaglandin f synthase 0.0031 0.0129 0.2008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0021 0.007 0.007
Brugia malayi SH2 domain containing protein 0.001 0.0005 0.0005
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.0012 0.0014
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0127 0.0683 0.3926
Echinococcus granulosus caspase 8 0.0098 0.0517 0.0623
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0043 0.0199 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0044 0.0125
Echinococcus granulosus aldo keto reductase 0.0031 0.0129 0.0155
Schistosoma mansoni nephrin related 0.0028 0.011 0.0133
Loa Loa (eye worm) oxidoreductase 0.0031 0.0129 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0043 0.0199 0.0199
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0052 0.0812
Trichomonas vaginalis FMN-dependent NADH-azoreductase, putative 0.0022 0.0075 0.0214
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0154 0.0883
Loa Loa (eye worm) hypothetical protein 0.0101 0.0532 0.0532
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0037 0.0164 0.0944
Schistosoma mansoni lipoxygenase 0.0061 0.03 0.0361
Schistosoma mansoni peroxidasin 0.0028 0.011 0.0133
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0066 0.0066
Echinococcus multilocularis neuropeptide receptor A26 0.0513 0.293 0.3529
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0066 0.0238
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0199 0.0199
Echinococcus multilocularis aldo keto reductase 0.0031 0.0129 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0044 0.0125
Echinococcus granulosus protein tyrosine phosphatase n9 0.0012 0.0015 0.0018
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Trypanosoma brucei metacaspase MCA3 0.0098 0.0517 0.8068
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0154 0.2394
Brugia malayi cytokine inducible SH2-containing protein 5 0.001 0.0005 0.0005
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0239 0.0288
Schistosoma mansoni netrin receptor unc5 0.0063 0.0312 0.0376
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0239 0.3729
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0043 0.0199 0.0199
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0009 0.0002 0.0002
Brugia malayi STAT protein, DNA binding domain containing protein 0.001 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0017 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0035 0.015 0.015
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0268 0.4178
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0012 0.0015 0.0018
Schistosoma mansoni pol-related 0.0031 0.0129 0.0155
Loa Loa (eye worm) hypothetical protein 0.0021 0.007 0.007
Trichomonas vaginalis pten, drome, putative 0.0012 0.0015 0.0044
Schistosoma mansoni GTPase activating protein 0.001 0.0005 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0019 0.0058 0.0334
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0048 0.0048
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.0129 0.0369
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0019 0.0058 0.0334
Giardia lamblia NADPH oxidoreductase, putative 0.0022 0.0075 0.0207
Schistosoma mansoni DNA polymerase eta 0.0035 0.0154 0.0185
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0166 0.02
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0199
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0009 0.0002 0.0008
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0601 0.0724
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.011 0.011
Trypanosoma cruzi metacaspase, putative 0.0098 0.0517 0.8068
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0029 0.0114 0.1085
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.0546 0.0658
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0031 0.0129 0.0768
Trichomonas vaginalis spcc417.12 protein, putative 0.0045 0.021 0.0602
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0012 0.0015 0.0018
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0019 0.0058 0.0334
Brugia malayi Protein kinase domain containing protein 0.001 0.0005 0.0005
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0239 0.0239
Echinococcus granulosus SHC transforming protein 3 0.001 0.0005 0.0006
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.004 0.004
Schistosoma mansoni cytochrome P450 0.0019 0.0058 0.007
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0048 0.0742
Echinococcus multilocularis lachesin 0.0028 0.011 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0161 0.0461
Brugia malayi Protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Plasmodium falciparum Appr-1-p processing domain protein 0.0014 0.0027 0.0523
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0012 0.0015 0.0018
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0028 0.011 0.0133
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0234 0.3654
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0142 0.0171
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0609 0.3486 1
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0035 0.0149 0.018
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0052 0.0763
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0074 0.0706
Schistosoma mansoni gliotactin 0.0045 0.021 0.0253
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.0234 0.3433
Schistosoma mansoni hypothetical protein 0.0081 0.0419 0.0505
Echinococcus granulosus suppressor of cytokine signaling 7 0.001 0.0005 0.0006
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0012 0.0015 0.0238
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0017 0.0044 0.0681
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0159 0.0912
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0066 0.008
Schistosoma mansoni hypothetical protein 0.0022 0.0073 0.0088
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0005 0.0005
Brugia malayi hypothetical protein 0.0022 0.0073 0.0073
Onchocerca volvulus 0.001 0.0005 0.0018
Echinococcus multilocularis voltage gated potassium channel 0.0012 0.0016 0.0019
Echinococcus multilocularis N chimaerin 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0012 0.0015 0.0018
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.007 0.02
Onchocerca volvulus 0.0012 0.0015 0.0055
Echinococcus multilocularis hemicentin 1 0.0109 0.0582 0.0701
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0129 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Plasmodium falciparum thioredoxin reductase 0.0052 0.0249 0.4818
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.008
Echinococcus granulosus expressed protein 0.0037 0.0161 0.0194
Brugia malayi Variant SH3 domain containing protein 0.001 0.0005 0.0005
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0601 0.0724
Echinococcus multilocularis netrin receptor unc 5 0.0063 0.0312 0.0376
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0028 0.011 0.0133
Brugia malayi hypothetical protein 0.026 0.1457 0.1457
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0043 0.0199 0.0199
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0129 0.0155
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Echinococcus multilocularis c src tyrosine kinase 0.001 0.0005 0.0006
Plasmodium falciparum glutathione reductase 0.0018 0.0052 0.1006
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0073 0.0088
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0045 0.021 0.0253
Echinococcus granulosus MACRO domain containing protein 2 0.0014 0.0027 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Giardia lamblia GTOR 0.0049 0.0234 0.0666
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0195 0.1081 0.1081
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0025 0.0092 0.0092
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0044 0.0681
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0031 0.0129 0.1887
Trypanosoma brucei unspecified product 0.0024 0.009 0.1397
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0048 0.0048
Entamoeba histolytica modulator of drug activity B homolog, putative 0.0022 0.0075 0.0214
Brugia malayi hypothetical protein 0.0109 0.0582 0.0582
Plasmodium vivax DNA repair protein REV1, putative 0.0011 0.0011 0.0221
Schistosoma mansoni tensin 0.001 0.0005 0.0006
Loa Loa (eye worm) cytochrome P450 0.0019 0.0058 0.0058
Echinococcus granulosus roundabout 2 0.0028 0.011 0.0133
Echinococcus granulosus FTZ F1 alpha 0.0043 0.0199 0.024
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0012 0.0015 0.0018
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0073 0.1417
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0129 0.0155
Trypanosoma brucei chrX additional, unordered contigs 0.0011 0.0011 0.0178
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0074 0.0074
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0325 0.5073
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0183 0.0526
Loa Loa (eye worm) hypothetical protein 0.0103 0.0546 0.0546
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Schistosoma mansoni suppressor of cytokine signaling 0.001 0.0005 0.0006
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.007 0.0084
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0052 0.0812
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0129 0.0155
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0332 0.04
Echinococcus granulosus neuropeptide s receptor 0.0513 0.293 0.3529
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Brugia malayi Pre-SET motif family protein 0.0229 0.128 0.128
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0043 0.0199 0.0199
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0092 0.0265
Schistosoma mansoni regulator of G protein signaling 0.0021 0.007 0.0084
Toxoplasma gondii melibiase subfamily protein 0.0113 0.0601 0.5737
Onchocerca volvulus 0.0012 0.0015 0.0055
Brugia malayi ImpB/MucB/SamB family protein 0.0035 0.0154 0.0154
Echinococcus multilocularis SH2 domain containing adapter protein F 0.001 0.0005 0.0006
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0043 0.0199 0.024
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0012 0.0015 0.0018
Brugia malayi Carboxylesterase family protein 0.0045 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0021 0.007 0.007
Brugia malayi Immunoglobulin domain containing protein 0.0028 0.011 0.011
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0012 0.0015 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Onchocerca volvulus 0.0261 0.1464 0.5276
Schistosoma mansoni signal transduction protein lnk-related 0.001 0.0005 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0098 0.0517 1
Echinococcus multilocularis aldo keto reductase 0.0031 0.0129 0.0155
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0135 0.2608
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0092 0.0111
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0127 0.0683 0.0822
Schistosoma mansoni survival motor neuron protein 0.0053 0.0255 0.0308
Schistosoma mansoni nephrin 0.0028 0.011 0.0133
Schistosoma mansoni inositol monophosphatase 0.0041 0.0183 0.0221
Mycobacterium ulcerans arylsulfatase AtsD 0.0009 0.0002 0.0013
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0021 0.0067 0.1039
Echinococcus multilocularis 0.001 0.0005 0.0006
Brugia malayi Variant SH3 domain containing protein 0.001 0.0005 0.0005
Echinococcus multilocularis suppressor of cytokine signaling 7 0.001 0.0005 0.0006
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0035 0.015 0.0181
Schistosoma mansoni inositol monophosphatase 0.0041 0.0183 0.0221
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Onchocerca volvulus 0.001 0.0005 0.0018
Schistosoma mansoni vav2 0.001 0.0005 0.0006
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0129 0.0155
Loa Loa (eye worm) hypothetical protein 0.0101 0.0532 0.0532
Echinococcus granulosus peroxidasin 0.0028 0.011 0.0133
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0233 0.1301 0.1567
Leishmania major tyrosine specific protein phosphatase, putative 0.0012 0.0015 0.0224
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0052 0.0497
Brugia malayi nuclear receptor NHR-88 0.002 0.0066 0.0066
Echinococcus granulosus lachesin 0.0028 0.011 0.0133
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.0058 0.0906
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0183 0.1054
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0303 0.0365
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0073 0.0088
Giardia lamblia NADPH oxidoreductase, putative 0.0022 0.0075 0.0207
Loa Loa (eye worm) CYP4Cod1 0.0037 0.0164 0.0164
Onchocerca volvulus 0.0081 0.0419 0.1511
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0161 0.0461
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0028 0.011 0.0133
Schistosoma mansoni ferritin light chain 0.0009 0.0002 0.0002
Onchocerca volvulus 0.001 0.0005 0.0018
Echinococcus granulosus SH2 motif 0.001 0.0005 0.0006
Brugia malayi Immunoglobulin domain containing protein 0.0028 0.011 0.011
Schistosoma mansoni tyrosine-protein kinase zap-70 0.001 0.0005 0.0006
Echinococcus multilocularis tumor protein p63 0.0704 0.4039 0.4864
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0019 0.0058 0.0334
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0164 0.0164
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0249 0.03
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0131 0.0158
Echinococcus granulosus tyrosine protein kinase Srms 0.001 0.0005 0.0006
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0129 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0022 0.0075 0.0214
Echinococcus multilocularis tyrosine protein kinase Fgr 0.001 0.0005 0.0006
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0142 0.0171
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0016 0.0019
Echinococcus granulosus serine protein kinase ATM 0.0009 0.0002 0.0002
Onchocerca volvulus 0.003 0.012 0.0431
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.001 0.0005 0.0018
Giardia lamblia Fructose-bisphosphate aldolase 0.0609 0.3486 1
Schistosoma mansoni shc transforming protein 0.001 0.0005 0.0006
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0019 0.0058 0.0334
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0043 0.0199 0.0199
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0019 0.0058 0.0334
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0233 0.1301 0.1567
Onchocerca volvulus 0.001 0.0005 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.007 0.02
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0043 0.0199 0.024
Echinococcus granulosus para nitrobenzyl esterase 0.0045 0.021 0.0253
Trypanosoma brucei Macro domain containing protein, putative 0.0014 0.0027 0.0422
Brugia malayi hypothetical protein 0.002 0.0066 0.0066
Echinococcus granulosus axis inhibition protein axin 0.0021 0.007 0.0084
Schistosoma mansoni cell adhesion molecule 0.0028 0.011 0.0133
Echinococcus multilocularis ecdysone induced protein 78C 0.0043 0.0199 0.024
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0043 0.0199 0.024
Brugia malayi ecdysteroid receptor 0.0043 0.0199 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0199 0.024
Schistosoma mansoni cell adhesion molecule 0.0028 0.011 0.0133
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0052 0.0812
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0012 0.0015 0.0238
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0019 0.0058 0.0334
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0199 0.024
Schistosoma mansoni polycystin 1-related 0.0022 0.0073 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0161 0.0461
Schistosoma mansoni tyrosine kinase 0.001 0.0005 0.0006
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0135 0.2608
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0205 0.0246
Onchocerca volvulus Cell death protein 3 homolog 0.0098 0.0517 0.1865
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.0234 0.3433
Brugia malayi basement membrane proteoglycan precursor 0.0028 0.011 0.011
Brugia malayi glutathione reductase 0.0052 0.0249 0.0249
Onchocerca volvulus 0.0081 0.0419 0.1511
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0018
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0266 0.2538
Schistosoma mansoni nuclear receptor 0.002 0.0066 0.008
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0073 0.0073
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0306 0.4767
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0298 0.1676 1
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0233 0.1301 0.1567
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.011 0.011
Echinococcus granulosus microtubule associated protein 2 0.1438 0.8303 1
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.0517 0.1484
Schistosoma mansoni apoferritin-2 0.0009 0.0002 0.0002
Onchocerca volvulus 0.0487 0.2775 1
Entamoeba histolytica hypothetical protein, conserved 0.0014 0.0027 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0002 0.0005
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0183 0.2684
Entamoeba histolytica recQ family helicase, putative 0.0011 0.001 0.0027
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0249 0.3887
Trypanosoma cruzi aldo/keto reductase, putative 0.0031 0.0129 0.2008
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0019 0.0058 0.0334
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0127 0.0683 0.0822
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.007 0.007
Loa Loa (eye worm) intermediate filament protein 0.003 0.012 0.012
Echinococcus granulosus nuclear factor of activated T cells 5 0.034 0.1922 0.2315
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0138 0.0751 0.0905
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0239 0.0288
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0048 0.0057
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0043 0.0199 0.024
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Brugia malayi Sulfatase family protein 0.0009 0.0002 0.0002
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0129 0.0369
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.0052 0.1006
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0118 0.0636 0.3794
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0092 0.0265
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.001 0.0005 0.0006
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0012 0.0015 0.0015
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0183 0.0221
Echinococcus multilocularis tyrosine protein kinase Abl 0.001 0.0005 0.0006
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0298 0.1676 0.9639
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0035 0.0154 0.0185
Echinococcus multilocularis caspase 0.0098 0.0517 0.0623
Brugia malayi Carboxylesterase family protein 0.0101 0.0532 0.0532
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0048 0.0742
Giardia lamblia Protein LRP16 0.0014 0.0027 0.0071
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0641 0.184
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0019 0.0058 0.0334
Schistosoma mansoni flap endonuclease-1 0.0026 0.0098 0.0118
Onchocerca volvulus 0.003 0.012 0.0431
Schistosoma mansoni nuclear hormone receptor 0.002 0.0066 0.008
Onchocerca volvulus 0.0045 0.021 0.0756
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0019 0.0058 0.0334
Mycobacterium ulcerans bacterioferritin BfrB 0.0009 0.0002 0.0009
Echinococcus multilocularis flap endonuclease 1 0.0029 0.0114 0.0137
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.001 0.0005 0.0006
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0009 0.0002 0.0006
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0012 0.0015 0.0018
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0118 0.0636 0.3658
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0325 0.0325
Echinococcus multilocularis tyrosine protein kinase Fyn 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0075 0.0383 0.0383
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0325 0.0325
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0012 0.0015 0.0018
Mycobacterium tuberculosis Probable dehydrogenase 0.0118 0.0636 0.3658
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0183 0.1748
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Trypanosoma brucei metacaspase MCA2 0.0098 0.0517 0.8068
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0127 0.0683 1
Loa Loa (eye worm) inositol-1 0.0041 0.0183 0.0183
Echinococcus granulosus ecdysone induced protein 78C 0.0043 0.0199 0.024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0098 0.0517 0.1484
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0161 0.0461
Schistosoma mansoni basigin related 0.0028 0.011 0.0133
Leishmania major DNA damage repair protein, putative 0.0011 0.0011 0.0167
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.001 0.0005 0.0006
Echinococcus granulosus N chimaerin 0.001 0.0005 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0027 0.0523
Echinococcus granulosus aldehyde reductase 0.0022 0.0076 0.0092
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0045 0.021 0.021
Brugia malayi tailless protein 0.002 0.0066 0.0066
Leishmania major phosphatidylinositol 3-kinase, putative 0.0017 0.0044 0.064
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0073 0.0088
Echinococcus granulosus voltage gated potassium channel 0.0012 0.0016 0.0019
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.0058 0.007
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0074 0.0089
Loa Loa (eye worm) SH2 domain-containing protein 0.001 0.0005 0.0005
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0012 0.0015 0.0238
Loa Loa (eye worm) glutathione reductase 0.0052 0.0249 0.0249
Giardia lamblia Aldose reductase 0.0031 0.0129 0.0363
Echinococcus multilocularis tyrosine protein kinase Blk 0.001 0.0005 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0043 0.0199 0.0199
Echinococcus granulosus neuroglian 0.0028 0.011 0.0133
Brugia malayi hypothetical protein 0.001 0.0005 0.0005
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.004 0.0178 0.0215
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.021 0.0253
Treponema pallidum ATP-dependent DNA helicase 0.0011 0.0012 0.003
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0167 0.048
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0048 0.0057
Brugia malayi hypothetical protein 0.001 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Trypanosoma brucei metacaspase 0.0098 0.0517 0.8068
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0092 0.1351
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0012 0.0015 0.0018
Schistosoma mansoni regulator of G protein signaling 0.0021 0.007 0.0084
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0018
Onchocerca volvulus 0.0012 0.0015 0.0055
Plasmodium vivax SET domain protein, putative 0.0033 0.0142 0.2737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0119 0.0341
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0092 0.1438
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0199 0.024
Brugia malayi nuclear receptor RXR 0.002 0.0066 0.0066
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0383 0.0462
Echinococcus granulosus traf and tnf receptor associated protein 0.0195 0.1081 0.1302
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0601 0.0724
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0043 0.0199 0.024
Onchocerca volvulus 0.0012 0.0015 0.0055
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0098 0.0517 0.1484
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0075 0.0383 0.11
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0332 0.04
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0239 0.3729
Brugia malayi Flap endonuclease-1 0.0029 0.0114 0.0114
Brugia malayi MH2 domain containing protein 0.0131 0.071 0.071
Echinococcus granulosus tyrosine protein kinase Fyn 0.001 0.0005 0.0006
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0043 0.0199 0.0717
Echinococcus granulosus roundabout 2 0.0028 0.011 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0234 0.0672
Loa Loa (eye worm) hypothetical protein 0.0022 0.0074 0.0074
Plasmodium falciparum metacaspase 1 0.0098 0.0517 1
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0052 0.0052
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.008 0.0097
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0017 0.0044 0.0681
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0006
Brugia malayi Carboxylesterase family protein 0.0101 0.0532 0.0532
Trypanosoma brucei DNA damage repair protein, putative 0.0011 0.0011 0.0178
Loa Loa (eye worm) TK protein kinase 0.001 0.0005 0.0005
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0156 0.2427
Trypanosoma cruzi metacaspase 5, putative 0.0098 0.0517 0.8068
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0027
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0298 0.0359
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0074 0.0089
Schistosoma mansoni aldo-keto reductase 0.0031 0.0129 0.0155
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.007 0.0084
Brugia malayi Melibiase family protein 0.0075 0.0383 0.0383
Echinococcus granulosus SH2 domain containing adapter protein F 0.001 0.0005 0.0006
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0019 0.0058 0.0334
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Onchocerca volvulus 0.001 0.0005 0.0018
Brugia malayi Thioredoxin reductase 0.0052 0.0249 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.0641 0.3826
Loa Loa (eye worm) flap endonuclease-1 0.0029 0.0114 0.0114
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0129 0.0155
Schistosoma mansoni cpg binding protein 0.0028 0.0112 0.0135
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0031 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0044 0.0125
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0009 0.0002 0.0006
Onchocerca volvulus 0.001 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.0035 0.0149 0.0149
Giardia lamblia Flap structure-specific endonuclease 0.0029 0.0114 0.032
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Mycobacterium ulcerans arylsulfatase AtsB 0.0009 0.0002 0.0013
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0012 0.0015 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0002 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.3486 1
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.0058 0.0554
Loa Loa (eye worm) hypothetical protein 0.0164 0.0901 0.0901
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0298 0.0359
Brugia malayi Protein-tyrosine phosphatase 1 0.0012 0.0015 0.0015
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0641 0.184
Mycobacterium ulcerans hypothetical protein 0.0011 0.0011 0.0066
Toxoplasma gondii thioredoxin reductase 0.0052 0.0249 0.2379
Echinococcus multilocularis nuclear factor of activated T cells 5 0.034 0.1922 0.2315
Loa Loa (eye worm) hypothetical protein 0.0164 0.0901 0.0901
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0029 0.0114 0.1773
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.007 0.0084
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0052 0.0063
Echinococcus multilocularis muscleblind protein 1 0.0164 0.0901 0.1085
Schistosoma mansoni titin 0.0109 0.0582 0.0701
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0058 0.0906
Echinococcus multilocularis NCK adaptor protein 0.001 0.0005 0.0006
Trypanosoma brucei Metacaspase-4 0.0098 0.0517 0.8068
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0019 0.0058 0.0334
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Loa Loa (eye worm) acetylcholinesterase 1 0.0101 0.0532 0.0532
Schistosoma mansoni rotamase 0.0037 0.0161 0.0194
Brugia malayi SH2 domain containing protein 0.001 0.0005 0.0005
Brugia malayi PXA domain containing protein 0.0021 0.007 0.007
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0092 0.0265
Brugia malayi Tensin 0.001 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0019 0.0058 0.0334
Echinococcus granulosus expressed protein 0.0009 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0011 0.0012 0.059
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0021 0.007 0.007
Echinococcus granulosus survival motor neuron protein 1 0.026 0.1457 0.1755
Schistosoma mansoni growth factor receptor-bound protein 0.001 0.0005 0.0006
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0113 0.0601 0.0724
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0233 0.1301 0.1567
Onchocerca volvulus 0.0012 0.0015 0.0055
Trypanosoma brucei trypanothione reductase 0.0052 0.0249 0.3887
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0012 0.0015 0.0018
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0048 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0083 0.1296
Echinococcus granulosus BC026374 protein S09 family 0.0045 0.021 0.0253
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0028 0.011 0.0133
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0035 0.0154 0.0154
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0019 0.0058 0.0334
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0048 0.0057
Echinococcus multilocularis neuroligin 0.0045 0.021 0.0253
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0029 0.0114 0.1666
Onchocerca volvulus Putative titin 0.0081 0.0419 0.1511
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0129 0.0155
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.011 0.011
Brugia malayi protein-tyrosine kinase 0.001 0.0005 0.0005
Echinococcus multilocularis aldo keto reductase 0.0031 0.0129 0.0155
Echinococcus multilocularis tensin 0.001 0.0005 0.0006
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Schistosoma mansoni SH2A 0.001 0.0005 0.0006
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0043 0.0199 0.024
Brugia malayi Muscleblind-like protein 0.0164 0.0901 0.0901
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0005 0.0005
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0005 0.0006
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0005 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0164 0.0164
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Giardia lamblia Protein tyrosine phosphatase 0.0012 0.0015 0.0037
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0052 0.0812
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0066 0.0066
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0018
Echinococcus granulosus signal transduction protein lnk realted 0.001 0.0005 0.0006
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0129 0.0155
Loa Loa (eye worm) RGS-3 protein 0.0021 0.007 0.007
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0092 0.0111
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.3486 1
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0048 0.0057
Leishmania major hypothetical protein, conserved 0.0017 0.0048 0.0697
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Schistosoma mansoni cell adhesion molecule 0.0028 0.011 0.0133
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0233 0.1301 0.1301
Brugia malayi Protein kinase domain containing protein 0.001 0.0005 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.0683 0.0822
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0229 0.128 0.128
Loa Loa (eye worm) TK/ABL protein kinase 0.001 0.0005 0.0005
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0062 0.0306 0.0877
Schistosoma mansoni hypothetical protein 0.0606 0.3472 0.4181
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0072 0.0087
Entamoeba histolytica deoxycytidyl transferase, putative 0.0035 0.0154 0.044
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0048 0.0454
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0129 0.0369
Echinococcus granulosus SH2 motif 0.001 0.0005 0.0006
Echinococcus multilocularis SH2 motif 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0234 0.0234
Plasmodium vivax JmjC domain containing protein 0.0017 0.0048 0.092
Loa Loa (eye worm) hypothetical protein 0.0018 0.0054 0.0054
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0017 0.0048 0.0048
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0239 0.0686
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0043 0.0199 0.024
Leishmania major cytochrome p450-like protein 0.0037 0.0164 0.2405
Echinococcus granulosus MACRO domain containing protein 2 0.0014 0.0027 0.0033
Echinococcus granulosus tensin 0.001 0.0005 0.0006
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0074 0.143
Echinococcus multilocularis growth factor receptor bound protein 2 0.001 0.0005 0.0006
Mycobacterium tuberculosis Probable oxidoreductase 0.0031 0.0129 0.0741
Brugia malayi hypothetical protein 0.0021 0.007 0.007
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0018
Schistosoma mansoni nck2/grb4 0.001 0.0005 0.0006
Echinococcus granulosus roundabout 2 0.0028 0.011 0.0133
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0066 0.008
Echinococcus granulosus tumor protein p63 0.0704 0.4039 0.4864
Schistosoma mansoni terminal deoxycytidyl transferase 0.0035 0.0154 0.0185
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0199 0.024
Echinococcus multilocularis microtubule associated protein 2 0.1438 0.8303 1
Echinococcus granulosus expressed protein 0.041 0.233 0.2807
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0183 0.0526
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Schistosoma mansoni tensin 0.001 0.0005 0.0006
Schistosoma mansoni lamin 0.003 0.012 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0199 0.0199
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0129 0.0369
Brugia malayi Sex muscle abnormal protein 5 0.001 0.0005 0.0005
Echinococcus multilocularis survival motor neuron protein 1 0.026 0.1457 0.1755
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.0234 0.0672
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0011 0.0178
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0641 0.0772
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0135 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0035 0.0154 0.0185
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0072 0.0072
Brugia malayi hypoxia-induced factor 1 0.0297 0.1671 0.1671
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Schistosoma mansoni protein tyrosine phosphatase 0.0012 0.0015 0.0018
Mycobacterium ulcerans lipoprotein LppD 0.0014 0.0027 0.0156
Leishmania major aldo-keto reductase-like protein 0.0031 0.0129 0.1887
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0043 0.0199 0.024
Onchocerca volvulus 0.002 0.0066 0.0238
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0052 0.0812
Brugia malayi Death domain containing protein 0.0035 0.0149 0.0149
Brugia malayi SH2 domain containing protein 0.001 0.0005 0.0005
Echinococcus granulosus caspase 0.0098 0.0517 0.0623
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0066 0.008
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0019 0.0058 0.0334
Onchocerca volvulus 0.0031 0.0129 0.0464
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0113 0.0601 0.0724
Schistosoma mansoni tyrosine kinase 0.001 0.0005 0.0006
Onchocerca volvulus 0.001 0.0005 0.0018
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0044 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0043 0.0199 0.0199
Schistosoma mansoni tyrosine kinase 0.001 0.0006 0.0007
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.007 0.0084
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0138 0.0751 0.0905
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0048 0.0057
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0017 0.0044 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0073 0.0088
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0012 0.0015 0.0018
Onchocerca volvulus 0.0012 0.0015 0.0055
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0129 0.0155
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Echinococcus granulosus SH2 domain containing protein 7 0.001 0.0005 0.0006
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0012 0.0015 0.0018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0098 0.0517 0.1484
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0012
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0012 0.0015 0.0015
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0092 0.0265
Onchocerca volvulus 0.001 0.0005 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.3486 1
Onchocerca volvulus 0.0031 0.0129 0.0464
Brugia malayi Nuclear hormone receptor E75 0.002 0.0066 0.0066
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0192 0.1064 0.1064
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.011 0.011
Giardia lamblia NADH oxidase lateral transfer candidate 0.0018 0.0052 0.0143
Echinococcus granulosus neuropeptide receptor A26 0.0513 0.293 0.3529
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0016 0.004 0.0048
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0066 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0028 0.011 0.0133
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0052 0.1006
Onchocerca volvulus 0.0045 0.021 0.0756
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0192 0.0552
Schistosoma mansoni hypothetical protein 0.001 0.0005 0.0006
Schistosoma mansoni neuroglian 0.0028 0.011 0.0133
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0073 0.1417
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Schistosoma mansoni jumonji domain containing protein 0.0065 0.0323 0.0389
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Entamoeba histolytica hypothetical protein, conserved 0.0014 0.0027 0.0078
Brugia malayi Appr-1-p processing enzyme family protein 0.0014 0.0027 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0119 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0176 0.0504
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0021 0.007 0.007
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0.0011 0.0109
Schistosoma mansoni DNA helicase recq5 0.0022 0.0074 0.0089
Loa Loa (eye worm) SRC-1 0.001 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0048 0.0057
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0066 0.0066
Onchocerca volvulus 0.0012 0.0015 0.0055
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0641 0.184
Echinococcus granulosus RUN 0.0022 0.0073 0.0088
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0092 0.0265
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0135 0.1287
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0249 0.4818
Schistosoma mansoni cpg binding protein 0.003 0.0121 0.0146
Brugia malayi SH2 domain containing protein 0.001 0.0005 0.0005
Brugia malayi ecdysone receptor 0.002 0.0066 0.0066
Trypanosoma brucei unspecified product 0.0024 0.009 0.1397
Echinococcus granulosus expressed conserved protein 0.001 0.0005 0.0006
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0011 0.0012 0.0231
Onchocerca volvulus 0.0012 0.0015 0.0055
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0325 0.0392
Echinococcus granulosus tensin C1 domain containing phosphatase 0.001 0.0005 0.0006
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0052 0.0763
Onchocerca volvulus 0.0012 0.0015 0.0055
Schistosoma mansoni aldo-keto reductase 0.0031 0.0129 0.0155
Schistosoma mansoni microtubule-associated protein tau 0.1438 0.8303 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0134 0.0384
Loa Loa (eye worm) hypothetical protein 0.0017 0.0048 0.0048
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0183 0.2857
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Trypanosoma brucei protein tyrosine phosphatase 1 0.0012 0.0015 0.0238
Brugia malayi nuclear receptor NHR-88 0.0043 0.0199 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0048 0.0057
Brugia malayi PXA domain containing protein 0.0021 0.007 0.007
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0012 0.0015 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Onchocerca volvulus Tyrosine kinase homolog 0.0081 0.0419 0.1511
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.3486 1
Echinococcus granulosus tyrosine protein kinase Lyn 0.001 0.0008 0.0009
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0037 0.0161 0.0161
Echinococcus multilocularis MACRO domain containing protein 2 0.0014 0.0027 0.0033
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0018
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0066 0.008
Entamoeba histolytica recQ family DNA helicase 0.0011 0.0012 0.0034
Mycobacterium leprae Possible regulatory protein 0.0025 0.0092 0.055
Brugia malayi hypothetical protein 0.0134 0.0724 0.0724
Mycobacterium ulcerans sulfatase 0.0009 0.0002 0.0013
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0132 0.0713 0.4253
Echinococcus granulosus tyrosine kinase 0.001 0.0005 0.0006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0199 0.0199
Schistosoma mansoni ferritin 0.0009 0.0002 0.0002
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0159 0.0946
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0092 0.0265
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0135 0.0387
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0005 0.0005
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.007 0.0084
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0135 1
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0025 0.0095 0.1479
Leishmania major cytochrome p450-like protein 0.0019 0.0058 0.0851
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0233 0.1301 0.1567
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Echinococcus multilocularis tyrosine protein kinase Fyn 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0045 0.021 0.021
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0142 0.0171
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.008 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0142 0.0171
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.008 0.0097
Schistosoma mansoni hypothetical protein 0.0014 0.0027 0.0033
Treponema pallidum NADH oxidase 0.0018 0.0052 0.0145
Brugia malayi Cytochrome P450 family protein 0.0037 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0037 0.0164 0.0164
Echinococcus multilocularis lamin dm0 0.003 0.012 0.0144
Loa Loa (eye worm) hypothetical protein 0.003 0.012 0.012
Onchocerca volvulus 0.0012 0.0015 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0156 0.2427
Toxoplasma gondii target of rapamycin (TOR), putative 0.0037 0.0161 0.1535
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0166 0.02
Echinococcus multilocularis Immunoglobulin 0.0028 0.011 0.0133
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0306 0.1758
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.0052 0.0149
Entamoeba histolytica protein kinase rad3, putative 0.0009 0.0002 0.0005
Schistosoma mansoni hypothetical protein 0.0019 0.0058 0.007
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0012 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0028 0.011 0.0133
Schistosoma mansoni hypothetical protein 0.001 0.0005 0.0006
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.001 0.0005 0.0006
Loa Loa (eye worm) protein tyrosine phosphatase 0.0012 0.0015 0.0015
Loa Loa (eye worm) carboxylesterase 0.0045 0.021 0.021
Echinococcus granulosus tyrosine protein kinase Fyn 0.001 0.0005 0.0006
Mycobacterium ulcerans arylsulfatase AtsD 0.0009 0.0002 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.007 0.02
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0306 0.4767
Echinococcus granulosus neuroligin 0.0045 0.021 0.0253
Entamoeba histolytica aldose reductase, putative 0.0031 0.0129 0.0369
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0043 0.0199 0.0199
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.0641 0.0772
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0129 0.0369
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.001 0.0011
Brugia malayi ImpB/MucB/SamB family protein 0.0035 0.0154 0.0154
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0066 0.008
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0306 0.4767
Brugia malayi bHLH-PAS transcription factor 0.0071 0.036 0.036
Onchocerca volvulus 0.0012 0.0015 0.0055
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0183 0.0221
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Schistosoma mansoni nuclear hormone receptor 0.002 0.0066 0.008
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0098 0.0517 0.0623
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0019 0.0058 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Brugia malayi Peroxidasin 0.0028 0.011 0.011
Echinococcus granulosus netrin receptor unc 5 0.0063 0.0312 0.0376
Echinococcus granulosus tyrosine protein kinase Fyn 0.001 0.0005 0.0006
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0012 0.0016 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0164 0.2552
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Echinococcus multilocularis neuropeptide s receptor 0.0513 0.293 0.3529
Trypanosoma cruzi aldo-keto reductase 0.0031 0.0129 0.2008
Echinococcus multilocularis 0.0019 0.0058 0.007
Schistosoma mansoni basigin related 0.0028 0.011 0.0133
Onchocerca volvulus 4.1 G protein, putative homolog 0.0012 0.0015 0.0055
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Schistosoma mansoni regulator of G protein signaling 0.0021 0.007 0.0084
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.004 0.0178 0.0215
Loa Loa (eye worm) hypothetical protein 0.0045 0.021 0.021
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.0049 0.0469
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0119 0.0341
Loa Loa (eye worm) hypothetical protein 0.173 1 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0073 0.0073
Mycobacterium tuberculosis Possible lipoprotein LppD 0.0014 0.0027 0.0156
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Leishmania major DNA polymerase kappa, putative 0.0042 0.0191 0.2802
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0199 0.0199
Entamoeba histolytica aldose reductase, putative 0.0031 0.0129 0.0369
Schistosoma mansoni tensin 0.001 0.0005 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0234 0.0672
Onchocerca volvulus 0.0012 0.0015 0.0055
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0135 0.0387
Echinococcus multilocularis tyrosine protein kinase Srms 0.001 0.0005 0.0006
Echinococcus multilocularis SH2 motif 0.001 0.0005 0.0006
Brugia malayi 6-phosphofructokinase 0.0119 0.0641 0.0641
Loa Loa (eye worm) hypothetical protein 0.0035 0.0152 0.0152
Echinococcus multilocularis SH2 motif 0.001 0.0005 0.0006
Echinococcus multilocularis aldehyde reductase 0.0022 0.0076 0.0092
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0183 0.2857
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0018
Onchocerca volvulus 0.0081 0.0419 0.1511
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0066 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0074 0.0212
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0072 0.0087
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0074 0.143
Plasmodium falciparum glutathione reductase 0.0052 0.0249 0.4818
Echinococcus granulosus tyrosine protein kinase shark 0.001 0.0006 0.0007
Echinococcus multilocularis hemicentin 1 0.0028 0.011 0.0133
Entamoeba histolytica hypothetical protein 0.0022 0.0075 0.0214
Echinococcus granulosus hypothetical protein 0.0031 0.0129 0.0155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.3486 1
Schistosoma mansoni thyroid hormone receptor 0.0182 0.1002 0.1207
Schistosoma mansoni growth factor receptor-bound protein 0.001 0.0005 0.0006
Echinococcus granulosus tyrosine protein kinase Src42A 0.001 0.0005 0.0006
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0048 0.0048
Echinococcus multilocularis carboxylesterase 5A 0.0101 0.0532 0.0641
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0344 0.1947 0.5584
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0098 0.0517 0.1484
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0183 0.0526
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0052 0.0763
Trypanosoma cruzi metacaspase, putative 0.0098 0.0517 0.8068
Schistosoma mansoni ferritin light chain 0.0009 0.0002 0.0002
Mycobacterium tuberculosis Probable reductase 0.0118 0.0636 0.3658
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0012 0.0015 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0239 0.3729
Mycobacterium ulcerans putative regulatory protein 0.0071 0.036 0.2068
Echinococcus multilocularis tyrosine protein kinase otk 0.0028 0.011 0.0133
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.0234 0.0672
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0092 0.0265
Echinococcus multilocularis SH2 domain containing protein 7 0.001 0.0005 0.0006
Brugia malayi 6-phosphofructokinase 0.0119 0.0641 0.0641
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.008 0.008
Leishmania major DNA polymerase eta, putative 0.0011 0.0011 0.0167
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Echinococcus granulosus phd:f box containing protein 0.0017 0.0048 0.0057
Echinococcus multilocularis tyrosine protein kinase Src42A 0.001 0.0005 0.0006
Schistosoma mansoni protein tyrosine phosphatase 0.0012 0.0015 0.0018
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0344 0.1947 0.5584
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Schistosoma mansoni nuclear receptor 0.002 0.0066 0.008
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0189 0.1048 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Echinococcus multilocularis 0.0012 0.0015 0.0018
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0233 0.1301 0.1301
Echinococcus multilocularis tyrosine protein kinase Fyn 0.001 0.0005 0.0006
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0098 0.0517 0.1484
Brugia malayi Heparan sulfate 0.0028 0.011 0.011
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0325 0.4766
Brugia malayi Tyrosine-protein kinase abl-1 0.001 0.0005 0.0005
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.004 0.0178 0.0215
Echinococcus multilocularis serine protein kinase ATM 0.0009 0.0002 0.0002
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0031 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0117 0.0336
Schistosoma mansoni ankyrin 23/unc44 0.0035 0.0149 0.018
Echinococcus granulosus tyrosine protein kinase Blk 0.001 0.0005 0.0006
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.007 0.0084
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0298 0.4365
Echinococcus granulosus axis inhibition protein axin 0.0021 0.007 0.0084
Schistosoma mansoni hypothetical protein 0.0014 0.0027 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0199 0.0199
Schistosoma mansoni rab6-interacting 0.0022 0.0073 0.0088
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0012 0.0114
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Echinococcus granulosus acetylcholinesterase 0.0101 0.0532 0.0641
Schistosoma mansoni tyrosine kinase 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0199
Loa Loa (eye worm) histone methyltransferase 0.001 0.0005 0.0005
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0098 0.0517 0.4937
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.008 0.008
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0048 0.0057
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0332 0.0332
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0239 0.0686
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0043 0.0199 0.024
Onchocerca volvulus 0.0045 0.021 0.0756
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.0129 0.0369
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0066 0.008
Schistosoma mansoni pcd6 interacting protein-related 0.0012 0.0015 0.0018
Loa Loa (eye worm) oxidoreductase 0.0031 0.0129 0.0129
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0044 0.0681
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0306 0.4767
Toxoplasma gondii aldose reductase, putative 0.0031 0.0129 0.1229
Echinococcus multilocularis BC026374 protein (S09 family) 0.0045 0.021 0.0253
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0016 0.0019
Onchocerca volvulus 0.0012 0.0015 0.0055
Trichomonas vaginalis set domain proteins, putative 0.0261 0.1463 0.4197
Loa Loa (eye worm) phosphofructokinase 0.0119 0.0641 0.0641
Echinococcus granulosus dnaJ subfamily B 0.0403 0.2289 0.2757
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0129 0.0155
Brugia malayi RhoGAP domain containing protein 0.001 0.0005 0.0005
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Onchocerca volvulus 0.0045 0.021 0.0756
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.007 0.02
Brugia malayi jmjC domain containing protein 0.0017 0.0048 0.0048
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0298 0.1714
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0191 0.2802
Onchocerca volvulus 0.0012 0.0015 0.0055
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0061 0.03 0.0361
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0383 0.0462
Loa Loa (eye worm) LAD-2 short isoform 0.0028 0.011 0.011
Echinococcus multilocularis Immunoglobulin 0.0028 0.011 0.0133
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0052 0.0812
Leishmania major DNA polymerase eta, putative 0.0035 0.0154 0.2249
Brugia malayi hypothetical protein 0.0021 0.007 0.007
Entamoeba histolytica hypothetical protein 0.0021 0.007 0.02
Loa Loa (eye worm) hypoxia-induced factor 1 0.0297 0.1671 0.1671
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0019 0.0058 0.0334
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.004 0.004
Loa Loa (eye worm) carboxylesterase 0.0045 0.021 0.021
Plasmodium falciparum DNA repair protein REV1, putative 0.0011 0.0011 0.0221
Leishmania major prostaglandin f synthase, putative 0.0031 0.0129 0.1887
Loa Loa (eye worm) hypothetical protein 0.0045 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0045 0.021 0.021
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.0234 0.0282
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0058 0.0906
Schistosoma mansoni tensin-related 0.001 0.0005 0.0006
Onchocerca volvulus 0.0031 0.0129 0.0464
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0092 0.0265
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0012 0.0015 0.0018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.007 0.007
Toxoplasma gondii aldehyde dehydrogenase 0.0127 0.0683 0.6514
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0012 0.0192
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0092 0.0111
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.001 0.0005 0.0006
Brugia malayi Protein kinase domain containing protein 0.001 0.0005 0.0005
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.007 0.0084
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0028 0.011 0.011
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0641 0.0641
Plasmodium falciparum flap endonuclease 1 0.0029 0.0114 0.2197
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0239 0.3729
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0135 0.0383
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.0058 0.0906
Echinococcus multilocularis suppressor of cytokine signaling 6 0.001 0.0005 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0199 0.024
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0109 0.0582 0.2097
Schistosoma mansoni roundabout 0.0028 0.011 0.0133
Loa Loa (eye worm) oxidoreductase 0.0031 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.008
Schistosoma mansoni tyrosine kinase 0.001 0.0005 0.0006
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0025 0.0092 0.4845
Loa Loa (eye worm) hypothetical protein 0.0487 0.2775 0.2775
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0017 0.0044 0.064
Onchocerca volvulus 0.0043 0.0199 0.0717
Entamoeba histolytica Flap nuclease, putative 0.0029 0.0114 0.0326
Onchocerca volvulus 0.0012 0.0015 0.0055
Echinococcus granulosus carboxylesterase 5A 0.0101 0.0532 0.0641
Schistosoma mansoni intermediate filament proteins 0.003 0.012 0.0144
Echinococcus granulosus acetylcholinesterase 0.0101 0.0532 0.0641
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.007 0.0084
Schistosoma mansoni caspase-7 (C14 family) 0.0098 0.0517 0.0623
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0019 0.0058 0.0334
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0035 0.0154 0.0185
Brugia malayi MAP kinase sur-1 0.005 0.0239 0.0239
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0035 0.0149 0.0149
Onchocerca volvulus 0.0045 0.021 0.0756
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.0641 0.1836
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0005 0.0006
Brugia malayi Doublecortin family protein 0.0022 0.0073 0.0073
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0074 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.0517 0.1484
Echinococcus multilocularis tyrosine protein kinase shark 0.001 0.0006 0.0007
Loa Loa (eye worm) STAT protein 0.001 0.0005 0.0005
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.001 0.0005 0.0006
Entamoeba histolytica SH2-protein kinase domain containing protein 0.001 0.0008 0.0022
Echinococcus multilocularis transfer RNA-Lys 0.0071 0.036 0.0433
Schistosoma mansoni suppressor of cytokine signaling 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0074 0.0074
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0012 0.0015 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.007 0.02
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0066 0.008
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0092 0.0265
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0325 0.5073
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0066 0.008
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0074 0.0212
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0009 0.0002 0.0002
Onchocerca volvulus 0.001 0.0005 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.3486 1
Entamoeba histolytica iron-sulfur flavoprotein, putative 0.0022 0.0075 0.0214
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0005 0.0005
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0035 0.0149 0.018
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0012 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0135 0.1287
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.0517 0.1484
Schistosoma mansoni loxhd1 0.0022 0.0073 0.0088
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0641 1
Onchocerca volvulus 0.0012 0.0015 0.0055
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0018 0.0052 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.0517 0.1484
Loa Loa (eye worm) hypothetical protein 0.0033 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Brugia malayi Protein kinase domain containing protein 0.001 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0019 0.0058 0.0334
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0239 0.0686
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0325 0.0392
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.007 0.0084
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0254 0.0254
Schistosoma mansoni septate junction protein 0.0028 0.011 0.0133
Loa Loa (eye worm) hypothetical protein 0.0349 0.1973 0.1973
Echinococcus granulosus suppressor of cytokine signaling 6 0.001 0.0005 0.0006
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0028 0.011 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0255 0.0255
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0037 0.0161 0.0161
Echinococcus multilocularis aldo keto reductase 0.0031 0.0129 0.0155
Onchocerca volvulus 0.0033 0.0142 0.051
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0205 0.0246
Loa Loa (eye worm) SH2 domain-containing protein 0.001 0.0005 0.0005
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0043 0.0199 0.024
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0239 0.2282
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0118 0.0636 0.3658
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0012 0.0186
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0072 0.0072
Onchocerca volvulus 0.0031 0.0129 0.0464
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0012 0.0015 0.0018
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0028 0.011 0.0133
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.007 0.0084
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0298 0.0359
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0129 0.0155
Brugia malayi Cytochrome P450 family protein 0.0019 0.0058 0.0058
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0043 0.0199 0.024
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0176 0.2576
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Onchocerca volvulus 0.0012 0.0015 0.0055
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.001 0.0091
Mycobacterium leprae putative cytochrome p450 0.0019 0.0058 0.0347
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0102 0.0294
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0199
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0019 0.0058 0.0334
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.008
Trypanosoma brucei hypothetical protein, conserved 0.0011 0.0011 0.0178
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0306 0.4767
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0028 0.011 0.0133
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0019 0.0058 0.0334
Echinococcus granulosus lamin dm0 0.003 0.012 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0024 0.007
Loa Loa (eye worm) steroid hormone receptor 0.0043 0.0199 0.0199
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0048 0.0057
Loa Loa (eye worm) hypothetical protein 0.0322 0.1816 0.1816
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0072 0.0087
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.001 0.0005 0.0006
Echinococcus granulosus hemicentin 1 0.0109 0.0582 0.0701
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0012 0.0015 0.0015
Entamoeba histolytica SH2-protein kinase domain containing protein 0.001 0.0005 0.0014
Schistosoma mansoni DNA helicase recq1 0.0022 0.0074 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Brugia malayi jmjC domain containing protein 0.0017 0.0048 0.0048
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0028 0.011 0.0133
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0016
Trichomonas vaginalis ganglioside induced differentiation associated protein, putative 0.0014 0.0027 0.0078
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0129 0.0155
Loa Loa (eye worm) hypothetical protein 0.0098 0.0517 0.0517
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0306 0.4767
Brugia malayi SRC-1 0.001 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0325 0.0392
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0074 0.0706
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0129 0.0155
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0142 0.1351
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0028 0.011 0.0133
Echinococcus multilocularis ferritin 0.0009 0.0002 0.0002
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0129 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Echinococcus multilocularis thyroid hormone receptor alpha 0.0182 0.1002 0.1207
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Loa Loa (eye worm) RecQ helicase 0.0022 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Brugia malayi hypothetical protein 0.0012 0.0015 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0306 0.4767
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0074 0.0089
Loa Loa (eye worm) hypothetical protein 0.0029 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Onchocerca volvulus 0.0012 0.0015 0.0055
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0028 0.011 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0066 0.008
Entamoeba histolytica hypothetical protein 0.0021 0.007 0.02
Loa Loa (eye worm) hypothetical protein 0.026 0.1457 0.1457
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0129 0.0369
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0641 0.0772
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0048 0.0742
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Brugia malayi intermediate filament protein 0.003 0.012 0.012
Onchocerca volvulus 0.0012 0.0015 0.0055
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.0052 0.0149
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0019 0.0058 0.0334
Onchocerca volvulus 0.0028 0.0112 0.0403
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0135 0.0387
Onchocerca volvulus Netrin receptor homolog 0.0116 0.0621 0.2238
Mycobacterium ulcerans hydrolase 0.0009 0.0002 0.0013
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0052 0.0812
Schistosoma mansoni RAR-like nuclear receptor 0.0043 0.0199 0.024
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.0164 0.256
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0118 0.0636 0.3658
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0129 0.0155
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0129 0.0369
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.0129 0.0369
Echinococcus multilocularis signal transduction protein lnk realted 0.001 0.0005 0.0006
Echinococcus multilocularis traf and tnf receptor associated protein 0.0195 0.1081 0.1302
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0073 0.0088
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0019 0.0058 0.0334
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0135 0.0387
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0129 0.0369
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0127 0.1985
Echinococcus multilocularis Immunoglobulin subtype 0.0028 0.011 0.0133
Leishmania major DNA polymerase kappa, putative 0.0011 0.0011 0.0167
Plasmodium vivax metacaspase 1, putative 0.0098 0.0517 1
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0019 0.0058 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.0517 0.1484
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0132 0.0713 0.4099
Brugia malayi nuclear hormone receptor 0.0043 0.0199 0.0199
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.001 0.0005 0.0005
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0129 0.0369
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0239 0.0288
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0012 0.0015 0.0018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0074 0.0212
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0306 0.1758
Plasmodium falciparum metacaspase-like protein 0.0098 0.0517 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0135 0.2608
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0161 0.0461
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.004 0.0178 0.0215
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0048 0.092
Echinococcus multilocularis tensin 0.001 0.0005 0.0006
Trichomonas vaginalis flap endonuclease-1, putative 0.0029 0.0114 0.0326
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.007 0.0084
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0109 0.0582 0.0701
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0183 0.022
Schistosoma mansoni septate junction protein 0.0028 0.011 0.0133
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0239 0.3503
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0066 0.008
Loa Loa (eye worm) transcription factor SMAD2 0.0131 0.071 0.071
Loa Loa (eye worm) DR-78 0.002 0.0066 0.0066
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0098 0.0517 0.1484
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0129 0.0155
Mycobacterium ulcerans bacterioferritin BfrA 0.0009 0.0002 0.0009
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0092 0.1438
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0043 0.0199 0.0199
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0019 0.0058 0.0334
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0239 0.3729
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0012 0.0015 0.0018
Plasmodium falciparum thioredoxin reductase 0.0018 0.0052 0.1006
Onchocerca volvulus 0.002 0.0066 0.0238
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0191 0.11
Echinococcus multilocularis expressed protein 0.0037 0.0161 0.0194
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0183 0.022
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Trichomonas vaginalis rotamase, putative 0.0036 0.0156 0.0447
Loa Loa (eye worm) MH2 domain-containing protein 0.0131 0.071 0.071
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0028 0.011 0.0133
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0012 0.0015 0.0018
Mycobacterium tuberculosis Probable oxidoreductase 0.0132 0.0713 0.4099
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0012 0.0015 0.0018
Brugia malayi Protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0052 0.0812
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.007 0.02
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0306 0.4767
Schistosoma mansoni hypothetical protein 0.0403 0.2289 0.2757
Schistosoma mansoni lipoxygenase 0.0022 0.0073 0.0088
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0012 0.0015 0.0018
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0135 0.0387
Echinococcus granulosus flap endonuclease 1 0.0029 0.0114 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0306 0.4767
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0012 0.0015 0.0018
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0142 0.0171
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0066 0.008
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0012 0.0015 0.0015
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0176 0.2742
Mycobacterium tuberculosis Probable sulfatase 0.0009 0.0002 0.0013
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0239 0.0288
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0072 0.0072
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0019 0.0058 0.0334
Trypanosoma brucei aldo-keto reductase, putative 0.0031 0.0129 0.2008
Schistosoma mansoni caspase-3 (C14 family) 0.0098 0.0517 0.0623
Schistosoma mansoni axis inhibition protein axin 0.0021 0.007 0.0084
Schistosoma mansoni septate junction protein 0.0028 0.011 0.0133
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0028 0.0113 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0102 0.0293
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0102 0.0294
Trichomonas vaginalis DNA polymerase eta, putative 0.0062 0.0306 0.0877
Schistosoma mansoni fkbp-rapamycin associated protein 0.0009 0.0002 0.0002
Echinococcus granulosus Immunoglobulin 0.0028 0.011 0.0133
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0129 0.0155
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0012 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0161 0.0461
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0306 0.4767
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0298 0.0298
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.007 0.007
Schistosoma mansoni rab6-interacting 0.0022 0.0073 0.0088
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.001 0.0005 0.0006
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Brugia malayi nuclear receptor RXR 0.0023 0.008 0.008
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0066 0.0066
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0005 0.0005
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0052 0.0812
Loa Loa (eye worm) hypothetical protein 0.0023 0.008 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0161 0.0461
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0118 0.0636 0.3658
Schistosoma mansoni caspase-7 (C14 family) 0.0098 0.0517 0.0623
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Echinococcus multilocularis para nitrobenzyl esterase 0.0045 0.021 0.0253
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0135 0.0387
Brugia malayi hypothetical protein 0.0009 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0102 0.0293
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0012 0.0015 0.0018
Mycobacterium ulcerans arylsulfatase, AslA 0.0009 0.0002 0.0013
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0098 0.0517 0.1484
Brugia malayi Pre-SET motif family protein 0.0033 0.0142 0.0142
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0036 0.0156 0.0447
Loa Loa (eye worm) hypothetical protein 0.0022 0.0073 0.0073
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0683 0.3926
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.004 0.0178 0.0215
Brugia malayi SH2 domain containing protein 0.001 0.0005 0.0005
Onchocerca volvulus 0.0031 0.0129 0.0464
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0129 0.0155
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0142 0.0171
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0.0011 0.0109
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0098 0.0517 0.1484
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0129 0.0155
Brugia malayi Prion-like- 0.0028 0.011 0.011
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.007 0.007
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.001 0.0005 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0127 0.1985
Loa Loa (eye worm) hypothetical protein 0.0045 0.021 0.021
Entamoeba histolytica SH2 domain containing protein 0.001 0.0005 0.0014
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0129 0.0155
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.007 0.0084
Echinococcus granulosus tyrosine protein kinase Btk29A 0.001 0.0005 0.0006
Trypanosoma cruzi metacaspase, putative 0.0098 0.0517 0.8068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0044 0.0125
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0052 0.2779
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0012 0.0015 0.0224
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0098 0.0517 0.4937
Schistosoma mansoni apoferritin-2 0.0009 0.0002 0.0002
Echinococcus multilocularis Ankyrin 0.0035 0.015 0.0181
Giardia lamblia NADPH oxidoreductase, putative 0.0022 0.0075 0.0207
Echinococcus multilocularis neuroglian 0.0028 0.011 0.0133
Brugia malayi indoleamine 2,3-dioxygenase 0.0606 0.3472 0.3472
Brugia malayi Carboxylesterase family protein 0.0045 0.021 0.021
Brugia malayi Protein kinase domain containing protein 0.001 0.0005 0.0005
Brugia malayi photoreceptor-specific nuclear receptor 0.0043 0.0199 0.0199
Brugia malayi Variant SH3 domain containing protein 0.001 0.0005 0.0005
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0012 0.0015 0.0044
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0028 0.011 0.0133
Onchocerca volvulus 0.001 0.0005 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0164 0.2552
Brugia malayi SH2 domain containing protein 0.001 0.0005 0.0005
Echinococcus granulosus growth factor receptor bound protein 2 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0074 0.1154
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.007 0.007
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.012 0.012
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0043 0.0199 0.0199
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0092 0.0092
Echinococcus multilocularis peroxidasin 0.0028 0.011 0.0133
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0183 0.2857
Schistosoma mansoni regulator of G protein signaling 0.0021 0.007 0.0084
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0191 0.2983
Brugia malayi Nuclear hormone receptor E75 0.002 0.0066 0.0066
Brugia malayi jmjC domain containing protein 0.0066 0.0332 0.0332
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Entamoeba histolytica hypothetical protein 0.0009 0.0002 0.0005
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.0129 0.0369
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0135 0.1287
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.007 0.0084
Schistosoma mansoni tyrosine kinase 0.001 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0606 0.3472 0.4181
Schistosoma mansoni coup transcription factor 0.0043 0.0199 0.024
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0098 0.0517 0.4937
Echinococcus multilocularis cpg binding protein 0.003 0.0121 0.0146
Trypanosoma cruzi metacaspase 5, putative 0.0098 0.0517 0.8068
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Onchocerca volvulus 0.0081 0.0419 0.1511
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Toxoplasma gondii Alpha-galactosidase 0.0016 0.004 0.0382
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0052 0.0812
Loa Loa (eye worm) oxidoreductase 0.0031 0.0129 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Onchocerca volvulus 0.0053 0.0255 0.092
Leishmania major protein kinase, putative 0.0031 0.0126 0.1845
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0641 0.0641
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0011 0.0012 0.0192
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Loa Loa (eye worm) SH2 domain-containing protein 0.001 0.0005 0.0005
Trichomonas vaginalis rotamase, putative 0.0037 0.0161 0.0461
Echinococcus multilocularis lysine specific demethylase 5A 0.0065 0.0323 0.0389
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0135 0.0387
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0683 0.3926
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0073 0.0088
Echinococcus granulosus muscleblind protein 0.0164 0.0901 0.1085
Echinococcus multilocularis acetylcholinesterase 0.0101 0.0532 0.0641
Entamoeba histolytica hypothetical protein, conserved 0.0014 0.0027 0.0078
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.007 0.007
Schistosoma mansoni cpg binding protein 0.003 0.0121 0.0146
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.0234 0.3654
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0012 0.0192
Echinococcus granulosus geminin 0.0186 0.1029 0.124
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0306 0.4767
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0239 0.0686
Loa Loa (eye worm) variant SH3 domain-containing protein 0.001 0.0005 0.0005
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0028 0.011 0.011
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0606 0.3472 0.4181
Schistosoma mansoni tensin-related 0.001 0.0005 0.0006
Echinococcus granulosus tyrosine protein kinase Src42A 0.001 0.0005 0.0006
Echinococcus multilocularis tyrosine kinase 0.001 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0186 0.1029 0.124
Leishmania major protein kinase, putative 0.0025 0.0095 0.139
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0018 0.0052 0.0299
Brugia malayi tRNA modification GTPase TrmE family protein 0.001 0.0005 0.0005
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0012 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0234 0.0234
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0098 0.0517 0.0623
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0066 0.008
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0019 0.0058 0.0334
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Schistosoma mansoni regulator of G protein signaling 0.0021 0.007 0.0084
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0029 0.0114 0.1773
Brugia malayi hypothetical protein 0.0012 0.0015 0.0015
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0129 0.0369
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0019 0.0058 0.0334
Schistosoma mansoni retinoic acid receptor RXR 0.0043 0.0199 0.024
Brugia malayi jmjC domain containing protein 0.0065 0.0323 0.0323
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0641 0.184
Brugia malayi hypothetical protein 0.0023 0.008 0.008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0298 0.1714
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0012 0.0015 0.0018
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0009 0.0002 0.0027
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0043 0.0199 0.0199
Brugia malayi Protein kinase domain containing protein 0.0035 0.0152 0.0152
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Echinococcus multilocularis RUN 0.0022 0.0073 0.0088
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0076 0.0455
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0074 0.0089
Echinococcus multilocularis tyrosine protein kinase Src64B 0.001 0.0005 0.0006
Schistosoma mansoni ferritin 0.0009 0.0002 0.0002
Echinococcus multilocularis tyrosine protein kinase ABL1 0.001 0.0005 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0176 0.0504
Onchocerca volvulus 0.0103 0.0546 0.1969
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Toxoplasma gondii non-specific serine/threonine protein kinase 0.001 0.0008 0.0076
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0005 0.0005
Brugia malayi polk-prov protein 0.0037 0.0164 0.0164
Echinococcus multilocularis acetylcholinesterase 0.0101 0.0532 0.0641
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0176 0.0504
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.001 0.0005 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0234 0.0672
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0129 0.0369
Brugia malayi Carboxylesterase family protein 0.0045 0.021 0.021
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0043 0.0199 0.024
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0012 0.0015 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0176 0.0504
Echinococcus multilocularis FTZ F1 alpha 0.0043 0.0199 0.024
Echinococcus multilocularis MACRO domain containing protein 2 0.0014 0.0027 0.0033
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0891 0.5124 0.6171
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0102 0.0294
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0065 0.0323 0.0389
Echinococcus granulosus intermediate filament protein 0.003 0.012 0.0144
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0017 0.0044 0.0053
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0012 0.0015 0.0044
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0092 0.0265
Schistosoma mansoni zinc finger protein 0.002 0.0066 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0127 0.1985
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0117 0.0336
Trypanosoma brucei cytochrome P450, putative 0.0037 0.0164 0.256
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0028 0.011 0.0133
Schistosoma mansoni hypothetical protein 0.0028 0.011 0.0133
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0009 0.0002 0.001
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0601 0.0724
Loa Loa (eye worm) cytochrome P450 family protein 0.004 0.018 0.018
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.021 0.0253
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0009 0.0002 0.0009
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.0234 0.0282
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0183 0.0526
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0011 0.0178
Onchocerca volvulus 0.0012 0.0015 0.0055
Echinococcus multilocularis Protein lozenge 0.0061 0.0302 0.0364
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.007 0.0084
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0199
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0641 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0606 0.3472 0.4181
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Trypanosoma brucei metacaspase 5, putative 0.0098 0.0517 0.8068
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.008 0.008
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.007 0.007
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0135 0.2608
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0018
Toxoplasma gondii macro domain-containing protein 0.0014 0.0027 0.0258
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.007 0.0084
Echinococcus granulosus tyrosine protein kinase Fps85D 0.001 0.0005 0.0006
Echinococcus granulosus ferritin 0.0009 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0053 0.0255 0.0308
Echinococcus granulosus c src tyrosine kinase 0.001 0.0005 0.0006
Echinococcus granulosus death domain containing protein 0.0035 0.0149 0.018
Brugia malayi hypothetical protein 0.0012 0.0015 0.0015
Echinococcus multilocularis roundabout 2 0.0028 0.011 0.0133
Trichomonas vaginalis ganglioside induced differentiation associated protein, putative 0.0014 0.0027 0.0078
Brugia malayi Immunoglobulin domain containing protein 0.0028 0.011 0.011
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0019 0.0058 0.0334
Leishmania major cytochrome p450-like protein 0.0019 0.0058 0.0851
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.0058 0.0851
Brugia malayi cytochrome P450 0.0019 0.0058 0.0058
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0074 0.0212
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.0641 0.3688
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0019 0.0058 0.0334
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0022 0.0075 0.0214
Echinococcus multilocularis hypothetical protein 0.0012 0.0015 0.0018
Schistosoma mansoni aryl hydrocarbon receptor 0.0096 0.0504 0.0608
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0112 0.0112
Brugia malayi nuclear hormone receptor 0.002 0.0066 0.0066
Giardia lamblia DINP protein human, muc B family 0.0042 0.0191 0.0543
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0022 0.0075 0.0214
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0043 0.0199 0.024
Echinococcus granulosus aldo keto reductase 0.0031 0.0129 0.0155
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0025 0.0095 0.1479
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0012 0.0016 0.0019
Trypanosoma brucei protein kinase, putative 0.005 0.0239 0.3729
Loa Loa (eye worm) RhoGAP domain-containing protein 0.001 0.0005 0.0005
Brugia malayi basement membrane proteoglycan 0.0028 0.011 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.014 0.0401
Brugia malayi Steroid receptor seven-up type 2 0.0043 0.0199 0.0199
Echinococcus multilocularis expressed protein 0.0009 0.0002 0.0002
Onchocerca volvulus 0.0022 0.0073 0.0264
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0325 0.0933
Brugia malayi hypothetical protein 0.0487 0.2775 0.2775
Schistosoma mansoni protein tyrosine phosphatase 0.0012 0.0015 0.0018
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Plasmodium vivax flap endonuclease 1, putative 0.0029 0.0114 0.2197
Onchocerca volvulus 0.001 0.0005 0.0018
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Brugia malayi Carboxylesterase family protein 0.0045 0.021 0.021
Schistosoma mansoni DNA polymerase IV / kappa 0.0011 0.0011 0.0014
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0052 0.1006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.011 0.011
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0129 0.0155
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0043 0.0199 0.024
Loa Loa (eye worm) hypothetical protein 0.0021 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Echinococcus granulosus hypothetical protein 0.001 0.0005 0.0006
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0239 0.3503
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0012 0.0015 0.0018
Brugia malayi hypothetical protein 0.002 0.0066 0.0066
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0183 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0142 0.0171
Echinococcus granulosus low density lipoprotein receptor ldl 0.0081 0.0419 0.0505
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0019 0.0058 0.0334
Schistosoma mansoni hypothetical protein 0.0028 0.011 0.0133
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0048 0.0454
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0043 0.0199 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0008 0.0023
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0019 0.0058 0.0334
Schistosoma mansoni neuroligin 3 (S09 family) 0.0045 0.021 0.0253
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0101 0.0532 0.0641
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0098 0.0517 0.1484
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Trypanosoma cruzi Macro domain containing protein, putative 0.0014 0.0027 0.0422
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0052 0.0812
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0019 0.0058 0.0334
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0012 0.018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Schistosoma mansoni basigin related 0.0028 0.011 0.0133
Echinococcus granulosus cpg binding protein 0.003 0.0121 0.0146
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0176 0.2742
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0002 0.0005
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0041 0.0183 0.0183
Toxoplasma gondii FATC domain-containing protein 0.0009 0.0002 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0161 0.0461
Loa Loa (eye worm) hypothetical protein 0.0031 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0005 0.0005
Loa Loa (eye worm) variant SH3 domain-containing protein 0.001 0.0005 0.0005
Onchocerca volvulus 0.0025 0.0092 0.0332
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0306 0.4767
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0135 0.0387
Echinococcus granulosus dna polymerase kappa 0.0062 0.0306 0.0368
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0052 0.0763
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Brugia malayi Cytochrome P450 family protein 0.0037 0.0164 0.0164
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0031 0.0129 0.1887
Echinococcus granulosus contactin 0.0109 0.0582 0.0701
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0135 0.0381
Brugia malayi Cytochrome P450 family protein 0.004 0.018 0.018
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0009 0.0002 0.0013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.3486 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.0641 0.9395
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0002 0.0006
Mycobacterium ulcerans carboxylesterase, LipT 0.0308 0.1739 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.3486 1
Schistosoma mansoni lamin 0.003 0.012 0.0144
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Toxoplasma gondii peptidylprolyl isomerase 0.0036 0.0156 0.1485
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0066 0.0066
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.0683 0.3926
Onchocerca volvulus 0.0012 0.0015 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0044 0.0125
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0009 0.0002 0.0013
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0011 0.0012 0.0117
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0239 0.068
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.0234 0.0282
Schistosoma mansoni lozenge 0.0061 0.0302 0.0364
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.007 0.0084
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0306 0.4767
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0019 0.0058 0.0334
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0057 0.0069
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0045 0.021 0.1206
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0298 0.1676 0.9639
Schistosoma mansoni hypothetical protein 0.0186 0.1029 0.124
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0027
Brugia malayi steroid hormone receptor 0.0043 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Echinococcus granulosus tyrosine protein kinase ABL1 0.001 0.0005 0.0006
Entamoeba histolytica aldose reductase, putative 0.0031 0.0129 0.0369
Echinococcus granulosus aldo keto reductase 0.0031 0.0129 0.0155
Echinococcus granulosus Immunoglobulin subtype 0.0028 0.011 0.0133
Onchocerca volvulus 0.0012 0.0015 0.0055
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.0234 0.3654
Trypanosoma cruzi metacaspase, putative 0.0098 0.0517 0.8068
Brugia malayi PAS domain containing protein 0.0096 0.0504 0.0504
Brugia malayi hypothetical protein 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0043 0.0199 0.0199
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0012 0.0015 0.0018
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0129 0.0369
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0298 0.1714
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.001 0.0005 0.0006
Schistosoma mansoni ferritin 0.0009 0.0002 0.0002
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0012 0.0015 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0641 0.184
Onchocerca volvulus 0.0022 0.0073 0.0264
Trypanosoma cruzi DNA polymerase eta, putative 0.0011 0.0011 0.0178
Schistosoma mansoni cell adhesion molecule 0.0028 0.011 0.0133
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0009 0.0002 0.0002
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.001 0.0005 0.0006
Brugia malayi phosphofructokinase 0.0119 0.0641 0.0641
Loa Loa (eye worm) hypothetical protein 0.0487 0.2775 0.2775
Brugia malayi hypothetical protein 0.0322 0.1816 0.1816
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0249 0.03
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0041 0.0183 0.0183
Echinococcus multilocularis caspase 8 0.0098 0.0517 0.0623
Brugia malayi Inositol-1 0.0041 0.0183 0.0183
Trypanosoma cruzi DNA damage repair protein, putative 0.0011 0.0011 0.0178
Mycobacterium leprae Conserved hypothetical protein 0.0019 0.0058 0.0347
Brugia malayi hypothetical protein 0.0045 0.021 0.021
Mycobacterium ulcerans oxidoreductase 0.0031 0.0129 0.0741
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0072 0.0087
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0045 0.021 0.0602
Loa Loa (eye worm) sex muscle abnormal protein 5 0.001 0.0005 0.0005
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0009 0.0002 0.0027
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.0052 0.1006
Entamoeba histolytica protein kinase, putative 0.001 0.0008 0.0022
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Schistosoma mansoni cell adhesion molecule 0.0028 0.011 0.0133
Brugia malayi hypothetical protein 0.0023 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0028 0.011 0.0133
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0167 0.048
Giardia lamblia Aldose reductase 0.0031 0.0129 0.0363
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0102 0.0293
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0036 0.0156 0.2427
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0176 0.0504
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.001 0.0005 0.0006
Giardia lamblia DNA damage repair protein 0.0011 0.0011 0.0026
Schistosoma mansoni single-minded 0.0096 0.0504 0.0608
Echinococcus granulosus tyrosine protein kinase otk 0.0028 0.011 0.0133
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0074 0.0074
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0035 0.0154 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.0517 0.1484
Echinococcus granulosus dna polymerase eta 0.0035 0.0154 0.0185
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0005
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0025 0.0095 0.1479
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0012 0.0015 0.0015
Echinococcus granulosus Immunoglobulin 0.0028 0.011 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.007 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0092 0.0265
Trichomonas vaginalis ganglioside induced differentiation associated protein, putative 0.0014 0.0027 0.0078
Schistosoma mansoni acetylcholinesterase 0.0045 0.021 0.0253
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0306 0.4767
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Onchocerca volvulus 0.0031 0.0129 0.0464
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.0234 0.3654
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0009 0.0002 0.0005
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0012 0.0186
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0239 0.0288
Echinococcus multilocularis roundabout 2 0.0028 0.011 0.0133
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0028 0.011 0.0133
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0009 0.0002 0.0002
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.001 0.0005 0.0006
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0098 0.0517 0.0623
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0052 0.0063
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0074 0.0089
Echinococcus granulosus lamin 0.003 0.012 0.0144
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0052 0.0812
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Brugia malayi hypothetical protein 0.0022 0.0073 0.0073
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.008 0.0097
Treponema pallidum fructose-bisphosphate aldolase 0.0609 0.3486 1
Echinococcus multilocularis caspase 2 0.0098 0.0517 0.0623
Schistosoma mansoni septate junction protein 0.0028 0.011 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Echinococcus granulosus NCK adaptor protein 0.001 0.0005 0.0006
Schistosoma mansoni adapter molecule crk 0.001 0.0005 0.0006
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.012 0.012
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0012
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0249 0.1434
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0008
Mycobacterium tuberculosis Possible hydrolase 0.0009 0.0002 0.0013
Brugia malayi jmjC domain containing protein 0.0017 0.0048 0.0048
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0009 0.0002 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0075 0.0214
Trypanosoma brucei DNA polymerase eta, putative 0.0035 0.0154 0.2394
Echinococcus multilocularis geminin 0.0186 0.1029 0.124
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0012 0.0015 0.0018
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0052 0.0063
Trichomonas vaginalis ferritin, putative 0.0009 0.0002 0.0005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0009 0.0002 0.0002
Loa Loa (eye worm) TK/FER protein kinase 0.001 0.0005 0.0005
Brugia malayi Cell death protein 3 precursor 0.0098 0.0517 0.0517
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0092 0.0111
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.001 0.0005 0.0006
Mycobacterium tuberculosis Carboxylesterase LipT 0.0308 0.1739 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.011 0.011
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0018 0.0052 0.0299
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0036 0.0156 0.228
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0052 0.2779
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0325 0.5073
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0028 0.011 0.0133
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0025 0.0095 0.1479
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0.0074 0.0206
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0066 0.008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0306 0.4767
Trypanosoma cruzi DNA damage repair protein, putative 0.0011 0.0011 0.0178
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0606 0.3472 0.3472
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0113 0.0601 0.0724
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.021 0.0253
Echinococcus multilocularis lamin 0.003 0.012 0.0144
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0017 0.0044 0.0053
Schistosoma mansoni BC026374 protein (S09 family) 0.0045 0.021 0.0253
Schistosoma mansoni cell adhesion molecule 0.0028 0.011 0.0133
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0199
Entamoeba histolytica hypothetical protein 0.0021 0.007 0.02
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0132 0.0713 0.4099
Schistosoma mansoni hypothetical protein 0.0138 0.0751 0.0905
Schistosoma mansoni ferritin 0.0009 0.0002 0.0002
Echinococcus multilocularis roundabout 2 0.0028 0.011 0.0133
Schistosoma mansoni axis inhibition protein axin 0.0021 0.007 0.0084
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0609 0.3486 1
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.007 0.0084
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0028 0.011 0.0133
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0011 0.001 0.0184
Echinococcus granulosus Ankyrin 0.0035 0.015 0.0181
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0641 0.184
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0129 0.0369
Brugia malayi Uncoordinated protein 44 0.0035 0.0149 0.0149
Loa Loa (eye worm) runx1 0.0061 0.0302 0.0302
Echinococcus granulosus single minded 2 0.0075 0.0381 0.0459
Schistosoma mansoni hypothetical protein 0.0028 0.011 0.0133
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.007 0.0084
Echinococcus multilocularis dna polymerase kappa 0.0062 0.0306 0.0368
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0009 0.0002 0.0009
Echinococcus multilocularis dnaJ subfamily B 0.0403 0.2289 0.2757
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.0641 0.3688
Echinococcus multilocularis SHC transforming protein 3 0.001 0.0005 0.0006
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0045 0.021 0.0253
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0019 0.0058 0.0334
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0012 0.0015 0.0018
Onchocerca volvulus 0.0012 0.0015 0.0055
Loa Loa (eye worm) carboxylesterase 0.0101 0.0532 0.0532
Brugia malayi SH2 domain containing protein 0.001 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0199
Echinococcus multilocularis tyrosine protein kinase Src42A 0.001 0.0005 0.0006
Brugia malayi hypothetical protein 0.0012 0.0015 0.0015
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0052 0.0497
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0066
Leishmania major metacaspase, putative 0.0098 0.0517 0.758
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.0164 0.256
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0019 0.0058 0.0334
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0048 0.0057
Echinococcus multilocularis suppressor of cytokine signaling 7 0.001 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0066 0.0238
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0052 0.0812
Schistosoma mansoni tyrosine kinase 0.0028 0.011 0.0133
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0109 0.0582 0.0582
Brugia malayi SH2 domain containing protein 0.001 0.0005 0.0005
Trypanosoma brucei unspecified product 0.0055 0.0268 0.4178
Echinococcus granulosus tyrosine kinase 0.001 0.0005 0.0006
Trypanosoma brucei DNA damage repair protein, putative 0.0011 0.0011 0.0178
Trichomonas vaginalis modulator of drug activity B, putative 0.0022 0.0075 0.0214
Loa Loa (eye worm) oxidoreductase 0.0031 0.0129 0.0129
Brugia malayi Variant SH3 domain containing protein 0.001 0.0005 0.0005

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 0.25 uM Antimicrobial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 harboring pFCA-lux AB gene measured under aerobic condition after 8 days by luminescence analysis ChEMBL. 22148391
MIC (functional) = 4.1 uM Antimicrobial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 harboring pFCA-lux AB gene measured under anaerobic condition after 11 days by luminescence analysis ChEMBL. 22148391

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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